Florian A Karreth

Florian A Karreth

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Florian A Karreth

Florian A Karreth

Publications by authors named "Florian A Karreth"

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A Roadmap for the Computational Prediction and Experimental Validation of Competitive Endogenous RNAs.

Methods Mol Biol 2019 ;1970:237-250

Department of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.

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http://dx.doi.org/10.1007/978-1-4939-9207-2_13DOI Listing
September 2019

Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition.

Mol Cell 2017 Aug 27;67(3):512-527.e4. Epub 2017 Jul 27.

Department of Pharmacology, Meyer Cancer Center, Weill Cornell Medical College, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.06.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698809PMC
August 2017

The utility of transposon mutagenesis for cancer studies in the era of genome editing.

Genome Biol 2015 Oct 19;16:229. Epub 2015 Oct 19.

Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1HH, UK.

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http://dx.doi.org/10.1186/s13059-015-0794-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612416PMC
October 2015

The BRAF pseudogene functions as a competitive endogenous RNA and induces lymphoma in vivo.

Cell 2015 Apr 2;161(2):319-32. Epub 2015 Apr 2.

Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.02.043DOI Listing
April 2015

Pseudogenes as competitive endogenous RNAs: target prediction and validation.

Methods Mol Biol 2014 ;1167:199-212

Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, CLS-401, Boston, MA, 02215, USA.

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http://link.springer.com/10.1007/978-1-4939-0835-6_13
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http://dx.doi.org/10.1007/978-1-4939-0835-6_13DOI Listing
January 2015

Role of BRAFV600E in the first preclinical model of multifocal infiltrating myopericytoma development and microenvironment.

J Natl Cancer Inst 2014 Aug 25;106(8). Epub 2014 Jul 25.

Department of Pathology, Massachusetts General Hospital (PMS) and Department of Medicine, Brigham and Women's Hospital (CP, EPH), Harvard Medical School, Boston, MA; Unit of Endocrinology, Department of Medicine, A. Gemelli, Catholic University, Roma, Italy (SN, AP); Division of Cancer Genetics, Department of Medicine (FAK, JC, PPP) and Laboratory of Human Thyroid Cancers Preclinical and Translational Research, Division of Cancer Biology and Angiogenesis, Department of Pathology, Center for Vascular Biology Research (MD, CN), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA; Department of Medicine (RM, CVC) and Department of Pathology (AH, HD, JL), Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, MA; Dermatopathologische Gemeinschaftspraxis, Siemensstrasse, Friedri chshafen, Germany (HK, TM); National Research Council (CNR-IBCN) and Department of Experimental Oncology, Regina Elena Cancer Institute, Rome, Italy (AF); Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA (EP, LEM); MIT/Broad Institute, Cambridge, MA (EP, LEM); Department of Plastic and Reconstructive Surgery, National Health Insurance Service Ilsan Hospital, Ilsan, Korea (SC); Department of Pathology (GF) and Department of Surgery (CPL), A. Gemelli, Catholic University, Roma, Italy; Department of Experimental and Clinical Medicine (AMDA) and Unit of Radiotherapy (OD), University of Catanzaro, Italy; Department of Nuclear Medicine, Beth Israel Deaconess Medical Center (JAP); Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (CF).

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http://dx.doi.org/10.1093/jnci/dju182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155429PMC
August 2014

Characterization of dual PTEN and p53-targeting microRNAs identifies microRNA-638/Dnm2 as a two-hit oncogenic locus.

Cell Rep 2014 Aug 31;8(3):714-22. Epub 2014 Jul 31.

Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.06.064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128194PMC
August 2014

Aberrant ceRNA activity drives lung cancer.

Cell Res 2014 Mar 14;24(3):259-60. Epub 2014 Feb 14.

Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.

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http://dx.doi.org/10.1038/cr.2014.21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945890PMC
March 2014

ceRNA cross-talk in cancer: when ce-bling rivalries go awry.

Cancer Discov 2013 Oct 26;3(10):1113-21. Epub 2013 Sep 26.

Cancer Genetics Program, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

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http://cancerdiscovery.aacrjournals.org/cgi/doi/10.1158/2159
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http://dx.doi.org/10.1158/2159-8290.CD-13-0202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3801300PMC
October 2013

Integrated transcriptional and competitive endogenous RNA networks are cross-regulated in permissive molecular environments.

Proc Natl Acad Sci U S A 2013 Apr 27;110(18):7154-9. Epub 2013 Mar 27.

Cancer Genetics Program, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.

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http://dx.doi.org/10.1073/pnas.1222509110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645534PMC
April 2013

Cathepsin B promotes the progression of pancreatic ductal adenocarcinoma in mice.

Gut 2012 Jun 9;61(6):877-84. Epub 2011 Dec 9.

Li Ka Shing Centre, Cancer Research UK Cambridge Research Institute, Cambridge, UK.

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http://dx.doi.org/10.1136/gutjnl-2011-300850DOI Listing
June 2012

C-Raf is required for the initiation of lung cancer by K-Ras(G12D).

Cancer Discov 2011 Jul 11;1(2):128-36. Epub 2011 May 11.

Li Ka Shing Centre, Cambridge Research Institute, Cancer Research UK, Cambridge, United Kingdom.

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http://dx.doi.org/10.1158/2159-8290.CD-10-0044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203527PMC
July 2011

Germline Brca2 heterozygosity promotes Kras(G12D) -driven carcinogenesis in a murine model of familial pancreatic cancer.

Cancer Cell 2010 Nov 4;18(5):499-509. Epub 2010 Nov 4.

Department of Oncology and the Medical Research Council Cancer Cell Unit, University of Cambridge, Hills Road, Cambridge CB2 0XZ, UK.

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http://dx.doi.org/10.1016/j.ccr.2010.10.015DOI Listing
November 2010

C-Raf inhibits MAPK activation and transformation by B-Raf(V600E).

Mol Cell 2009 Nov;36(3):477-86

Li Ka Shing Centre, Cambridge Research Institute, Cancer Research UK, Robinson Way, Cambridge CB2 0RE, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S109727650900782
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http://dx.doi.org/10.1016/j.molcel.2009.10.017DOI Listing
November 2009

Modelling oncogenic Ras/Raf signalling in the mouse.

Curr Opin Genet Dev 2009 Feb 7;19(1):4-11. Epub 2009 Feb 7.

Li Ka Shing Centre, Cambridge Research Institute, Cancer Research UK, Robinson Way, Cambridge, United Kingdom.

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http://dx.doi.org/10.1016/j.gde.2008.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389704PMC
February 2009