Florent Soubrier

Florent Soubrier

UNVERIFIED PROFILE

Are you Florent Soubrier?   Register this Author

Register author
Florent Soubrier

Florent Soubrier

Publications by authors named "Florent Soubrier"

Are you Florent Soubrier?   Register this Author

80Publications

3509Reads

26Profile Views

Clinical implications of CTNNA1 germline mutations in asymptomatic carriers.

Gastric Cancer 2019 07 4;22(4):899-903. Epub 2018 Dec 4.

Laboratoire d'Oncogénétique, Unité fonctionnelle d'Oncogénétique, Département de Génétique, Groupe Hospitalier Pitié-Salpêtrière AP-HP, 75013, Paris, France.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10120-018-00907-7
Publisher Site
http://dx.doi.org/10.1007/s10120-018-00907-7DOI Listing
July 2019

Familial breast cancer and DNA repair genes: Insights into known and novel susceptibility genes from the GENESIS study, and implications for multigene panel testing.

Int J Cancer 2019 04 13;144(8):1962-1974. Epub 2018 Nov 13.

Inserm, Paris, France.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/ijc.31921
Publisher Site
http://dx.doi.org/10.1002/ijc.31921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587727PMC
April 2019

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.

Authors:
Christopher J Rhodes Ken Batai Marta Bleda Matthias Haimel Laura Southgate Marine Germain Michael W Pauciulo Charaka Hadinnapola Jurjan Aman Barbara Girerd Amit Arora Jo Knight Ken B Hanscombe Jason H Karnes Marika Kaakinen Henning Gall Anna Ulrich Lars Harbaum Inês Cebola Jorge Ferrer Katie Lutz Emilia M Swietlik Ferhaan Ahmad Philippe Amouyel Stephen L Archer Rahul Argula Eric D Austin David Badesch Sahil Bakshi Christopher Barnett Raymond Benza Nitin Bhatt Harm J Bogaard Charles D Burger Murali Chakinala Colin Church John G Coghlan Robin Condliffe Paul A Corris Cesare Danesino Stéphanie Debette C Gregory Elliott Jean Elwing Melanie Eyries Terry Fortin Andre Franke Robert P Frantz Adaani Frost Joe G N Garcia Stefano Ghio Hossein-Ardeschir Ghofrani J Simon R Gibbs John Harley Hua He Nicholas S Hill Russel Hirsch Arjan C Houweling Luke S Howard Dunbar Ivy David G Kiely James Klinger Gabor Kovacs Tim Lahm Matthias Laudes Rajiv D Machado Robert V MacKenzie Ross Keith Marsolo Lisa J Martin Shahin Moledina David Montani Steven D Nathan Michael Newnham Andrea Olschewski Horst Olschewski Ronald J Oudiz Willem H Ouwehand Andrew J Peacock Joanna Pepke-Zaba Zia Rehman Ivan Robbins Dan M Roden Erika B Rosenzweig Ghulam Saydain Laura Scelsi Robert Schilz Werner Seeger Christian M Shaffer Robert W Simms Marc Simon Olivier Sitbon Jay Suntharalingam Haiyang Tang Alexander Y Tchourbanov Thenappan Thenappan Fernando Torres Mark R Toshner Carmen M Treacy Anton Vonk Noordegraaf Quinten Waisfisz Anna K Walsworth Robert E Walter John Wharton R James White Jeffrey Wilt Stephen J Wort Delphine Yung Allan Lawrie Marc Humbert Florent Soubrier David-Alexandre Trégouët Inga Prokopenko Richard Kittles Stefan Gräf William C Nichols Richard C Trembath Ankit A Desai Nicholas W Morrell Martin R Wilkins

Lancet Respir Med 2019 Mar 5;7(3):227-238. Epub 2018 Dec 5.

Department of Medicine, Imperial College London, London, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2213-2600(18)30409-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391516PMC
March 2019

Pulmonary vascular remodeling patterns and expression of general control nonderepressible 2 (GCN2) in pulmonary veno-occlusive disease.

J Heart Lung Transplant 2018 05 4;37(5):647-655. Epub 2017 Oct 4.

Institut National de la Santé et de la Recherche Unités Mixtes de Recherche_S 999, Pulmonary Hypertension: Pathophysiology and Novel Therapies, Hôpital Marie Lannelongue, Le Plessis-Robinson, Paris, France; Faculty of Medicine, Paris-South University, Kremlin-Bicêtre, Paris, France; Department of Pathology, Hôpital Marie Lannelongue, Le Plessis-Robinson, Paris, France. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10532498173203
Publisher Site
http://dx.doi.org/10.1016/j.healun.2017.09.022DOI Listing
May 2018

Prenatal molecular diagnosis in RASA1-related disease.

Prenat Diagn 2017 12 21;37(12):1261-1264. Epub 2017 Nov 21.

Service de Génétique, Hôpital Ambroise Paré, Assistance Publique Hôpitaux de Paris, Boulogne-Billancourt, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pd.5165DOI Listing
December 2017

Clinical and genetic findings in children with central nervous system arteriovenous fistulas.

Ann Neurol 2017 Dec 12;82(6):972-980. Epub 2017 Dec 12.

Department of genetics, Hopital Pitié-Salpêtrière, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ana.25106DOI Listing
December 2017

Clinical phenotypes and outcomes of heritable and sporadic pulmonary veno-occlusive disease: a population-based study.

Lancet Respir Med 2017 02 11;5(2):125-134. Epub 2017 Jan 11.

University Paris-Sud, Faculté de Médecine, Paris, F-94270, France; AP-HP, Centre de Référence de l'Hypertension Pulmonaire Sévère, Département Hospitalo-Universitaire (DHU) Thorax Innovation (TORINO), Service de Pneumologie, Hôpital de Bicêtre, Le Kremlin Bicêtre, Paris, France; UMR_S 999, Univ. Paris-Sud, INSERM, Laboratoire d'Excellence (LabEx) en Recherche sur le Médicament et l'Innovation Thérapeutique (LERMIT), Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, Paris, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2213-2600(16)30438-6DOI Listing
February 2017

Molecular Genetic Diagnosis of Pulmonary Arterial Hypertension: An Increased Complexity.

Rev Esp Cardiol (Engl Ed) 2016 Nov 12;69(11):1003-1004. Epub 2016 Sep 12.

Department of Genetics, GH Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris; UMR_S 1166, Université Paris-Sorbonne UPMC, and INSERM, Paris, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rec.2016.05.026DOI Listing
November 2016

Genetic analyses in a cohort of children with pulmonary hypertension.

Eur Respir J 2016 10 1;48(4):1118-1126. Epub 2016 Sep 1.

Genetics Dept, GH Pitié-Salpêtrière, Assistance Publique Hôpitaux de Paris, Paris, France Sorbonne Universités, UPMC Univ Paris 06, INSERM, UMR_S 1166-ICAN, Paris, France ICAN Institute for Cardiometabolism and Nutrition, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1183/13993003.00211-2016DOI Listing
October 2016

Pulmonary veno-occlusive disease.

Eur Respir J 2016 05 23;47(5):1518-34. Epub 2016 Mar 23.

Univ Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin Bicêtre, France AP-HP, Service de Pneumologie, Hôpital Bicêtre, Le Kremlin Bicêtre, France Inserm UMR_S 999, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1183/13993003.00026-2016DOI Listing
May 2016

Resident PW1+ Progenitor Cells Participate in Vascular Remodeling During Pulmonary Arterial Hypertension.

Circ Res 2016 Mar 12;118(5):822-33. Epub 2016 Jan 12.

From the INSERM, Institute of Cardiometabolism and Nutrition, UMR_S 1166-ICAN (F.D., T.H., V.M., C.C., V.B., E.Y.-G., J.-S.H., G.M., D.S., F.S., S.N.), UMS-030 CyPS, Paris, France (B.H.-C.), PECMV UMS28 (N.M.), INSERM, CNRS, CR7, Centre d'Immunologie et des Maladies Infectieuses (CIMI), U1135, ERL 8255 (G.M.), Sorbonne Universités, UPMC Univ Paris 06, Paris, France; Erasmus MC Stem Cell Institute, Rotterdam, The Netherlands (M.C.); Univ Paris-Sud, Université Paris Saclay, INSERM UMR-S 999, Labex LERMIT, Le Plessis-Robinson, Paris, France (P.D., E.F., M.H.); Service d'Anatomie Pathologique, Centre Chirurgical Marie Lannelongue, Le Plessis-Robinson, Paris, France (P.D.); Service de Chirurgie Thoracique et Vasculaire, Centre Chirurgical Marie Lannelongue, Le Plessis-Robinson, France (E.F.); Univ Paris-Sud, Université Paris Saclay, Le Kremlin-Bicêtre, Paris, France (M.H.); and Assistance Publique Hôpitaux de Paris, Service de Pneumologie, Centre de Référence de l'Hypertension Pulmonaire Sévère, Hôpital Bicêtre, Le Kremlin Bicêtre, France (M.H.).

View Article

Download full-text PDF

Source
http://circres.ahajournals.org/content/118/5/822.full.pdf
Web Search
http://circres.ahajournals.org/lookup/doi/10.1161/CIRCRESAHA
Publisher Site
http://dx.doi.org/10.1161/CIRCRESAHA.115.307035DOI Listing
March 2016

Genetic counselling in a national referral centre for pulmonary hypertension.

Eur Respir J 2016 Feb 23;47(2):541-52. Epub 2015 Dec 23.

Université Paris Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin Bicêtre, France AP-HP, Centre de Référence de l'Hypertension Pulmonaire Sévère, Département Hospitalo-Universitaire (DHU) Thorax Innovation (TORINO), Service de Pneumologie, Hôpital de Bicêtre, Le Kremlin Bicêtre, France UMR_S999, Université Paris-Sud, INSERM, Laboratoire d'Excellence (LabEx) en Recherche sur le Médicament et l'Innovation Thérapeutique (LERMIT), Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France

View Article

Download full-text PDF

Source
http://erj.ersjournals.com/content/erj/early/2015/12/22/1399
Web Search
http://erj.ersjournals.com/lookup/doi/10.1183/13993003.00717
Publisher Site
http://dx.doi.org/10.1183/13993003.00717-2015DOI Listing
February 2016

GENESIS: a French national resource to study the missing heritability of breast cancer.

BMC Cancer 2016 Jan 12;16:13. Epub 2016 Jan 12.

Inserm, U900, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12885-015-2028-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711059PMC
January 2016

Occupational exposure to organic solvents: a risk factor for pulmonary veno-occlusive disease.

Eur Respir J 2015 Dec 5;46(6):1721-31. Epub 2015 Nov 5.

Université Paris-Sud, Faculté de Médecine, Le Kremlin Bicêtre, France AP-HP, Centre de Référence de l'Hypertension Pulmonaire Sévère, Département Hospitalo-Universitaire (DHU) Thorax Innovation (TORINO), Service de Pneumologie, Hôpital de Bicêtre, Le Kremlin Bicêtre, France UMR_S999, Université Paris-Sud, INSERM, Laboratoire d'Excellence (LabEx) en Recherche sur le Médicament et l'Innovation Thérapeutique (LERMIT), Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France.

View Article

Download full-text PDF

Source
http://erj.ersjournals.com/content/erj/46/6/1721.full.pdf
Web Search
http://erj.ersjournals.com/lookup/doi/10.1183/13993003.00814
Publisher Site
http://dx.doi.org/10.1183/13993003.00814-2015DOI Listing
December 2015

Somatic c.34G>T KRAS mutation: a new prescreening test for MUTYH-associated polyposis?

Cancer Genet 2015 Jul-Aug;208(7-8):390-5. Epub 2015 Apr 23.

Department of Digestive Surgery, Hôpital Saint Antoine (Assistance Publique-Hôpitaux de Paris), Paris VI University, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cancergen.2015.04.005DOI Listing
October 2015

Characteristics of pulmonary arterial hypertension in affected carriers of a mutation located in the cytoplasmic tail of bone morphogenetic protein receptor type 2.

Chest 2015 May;147(5):1385-1394

University Paris-Sud, Le Kremlin-Bicêtre, France; Assistance Publique-Hôpitaux de Paris (AP-HP), Service de Pneumologie, Centre de Référence de l'Hypertension Pulmonaire Sévère, DHU Thorax Innovation, Hôpital Bicêtre, Le Kremlin-Bicêtre, France; Institut National de la Santé et de la Recherche Médicale (INSERM) U999, LabEx LERMIT, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00123692153836
Publisher Site
http://dx.doi.org/10.1378/chest.14-0880DOI Listing
May 2015

Mechanisms of exertional dyspnoea in pulmonary veno-occlusive disease with EIF2AK4 mutations.

Eur Respir J 2014 Oct 19;44(4):1069-72. Epub 2014 Aug 19.

AP-HP, Hôpital Universitaire de Bicêtre, Service d'Explorations Fonctionnelles Respiratoires, Centre de Référence de l'Hypertension Pulmonaire Sévère, DHU TORINO "Thorax Innovation", Le Kremlin-Bicêtre, France Univ. Paris-Sud 11, Faculté de médecine, Le Kremlin-Bicêtre, France INSERM U999, LabEx LERMIT, Centre Chirurgical Marie Lannelongue, Le Plessis-Robinson, France

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1183/09031936.00088914DOI Listing
October 2014

Proteomic identification of target proteins in normal but nonfertilizing sperm.

Fertil Steril 2014 Aug 29;102(2):372-80. Epub 2014 May 29.

Department of Histology and Reproductive Biology, UMPC (Paris VI), Tenon Hospital, Assistance Publique des Hôpitaux de Paris, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fertnstert.2014.04.039DOI Listing
August 2014

EIF2AK4 mutations cause pulmonary veno-occlusive disease, a recessive form of pulmonary hypertension.

Nat Genet 2014 Jan 1;46(1):65-9. Epub 2013 Dec 1.

1] Unité Mixte de Recherche en Santé (UMR_S 956), Université Pierre and Marie Curie Université Paris 06 (UPMC) and Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France. [2] Genetics Department, Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France. [3] Institute for Cardiometabolism and Nutrition (ICAN), Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.2844DOI Listing
January 2014

Genetics and genomics of pulmonary arterial hypertension.

J Am Coll Cardiol 2013 Dec;62(25 Suppl):D13-21

Centre de Référence de l'Hypertension Pulmonaire Sévère, Service de Pneumologie, Hôpital de Bicêtre, APHP, Le Kremlin Bicêtre, Université Paris-Sud, Faculté de Médecine, Le Kremlin Bicêtre; Département Hospitalo-Universitaire (DHU) thorax Innovation, AP-HP, Le Kremlin Bicêtre; UMR_S 999, INSERM and Université Paris-Sud, LabEx LERMIT, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France.

View Article

Download full-text PDF

Source
http://content.onlinejacc.org/data/Journals/JAC/23615/04015.
Web Search
http://content.onlinejacc.org/data/Journals/JAC/929484/10035
Web Search
http://linkinghub.elsevier.com/retrieve/pii/S073510971305878
Publisher Site
http://dx.doi.org/10.1016/j.jacc.2013.10.035DOI Listing
December 2013

Bone morphogenetic proteins protect pulmonary microvascular endothelial cells from apoptosis by upregulating α-B-crystallin.

Arterioscler Thromb Vasc Biol 2013 Nov 26;33(11):2577-84. Epub 2013 Sep 26.

From the UMR_S 956; Univ Paris 06 (UPMC); Institut National de la Santé et de la Recherche Médicale (INSERM), F-75013, Paris (M.C., M.E., O.P., S.M., F.D., K.M., S.N., F.S.); ICAN Institute for Cardiometabolism and Nutrition, Paris, France (M.E., O.P., S.M., F.D., S.N., F.S.); and UMR_S 999; INSERM; Univ Paris-Sud; LabEx LERMIT, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France (N.G.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.113.301976DOI Listing
November 2013

Clinical and genetic characteristics of Chinese patients with hereditary haemorrhagic telangiectasia-associated pulmonary hypertension.

Eur J Clin Invest 2013 Oct 6;43(10):1016-24. Epub 2013 Aug 6.

Department of Cardiology, the 4th Affiliated Hospital, Harbin Medical University, Harbin, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/eci.12138DOI Listing
October 2013

A novel channelopathy in pulmonary arterial hypertension.

N Engl J Med 2013 Jul;369(4):351-361

Departments of Pediatrics (L.M., E.B.R., W.K.C.), Pharmacology (D.R.-C., K.S.S., R.S.K.), and Pathology (A.B.), Columbia University Medical Center, New York; the Departments of Pediatrics (E.D.A.) and Medicine (J.E.L.), Vanderbilt University Medical Center, Nashville; the Genetics Department, Hospital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (APHP), Institut National de la Santé et de la Recherche Médicale (INSERM), and Université Pierre et Marie Curie (UPMC) Unité Mixte de Recherche en Santé (UMRS) 956, Institute of Cardiometabolism and Nutrition (ICAN) (M.E., F.S.); and INSERM-UPMC UMRS 937, ICAN (M.G., D.-A.T.) - all in Paris; and APHP, Département Hospitalo-Universitaire Thorax Innovation (DHU TORINO), Service de Pneumologie, Hôpital Bicêtre; Université Paris-Sud, Laboratoire d'Excellence en Recherche sur le Médicament et Innovation Thérapeutique (LERMIT); and INSERM UMRS 999 - all in Le Kremlin-Bicêtre, France (B.G., D.M., M.H.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1211097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792227PMC
July 2013

Somatic mosaicism and double somatic hits can lead to MSI colorectal tumors.

Fam Cancer 2013 Mar;12(1):27-33

Department of Digestive Surgery, Hôpital Saint Antoine (AP-HP), Paris VI University, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10689-012-9568-9DOI Listing
March 2013

From an ACE polymorphism to genome-wide searches for eQTL.

Authors:
Florent Soubrier

J Clin Invest 2013 Jan 2;123(1):111-2. Epub 2013 Jan 2.

Genetics Department, Hospital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, and UMR_S 956 UPMC-INSERM. 91 bvd de l’hôpital, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/JCI66618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533308PMC
January 2013

Inhibition of apelin expression by BMP signaling in endothelial cells.

Am J Physiol Cell Physiol 2012 Dec 15;303(11):C1139-45. Epub 2012 Aug 15.

UMR_S 956 INSERM, 91 bvd de l'hôpital, F-75634 Paris cedex 13, France.

View Article

Download full-text PDF

Source
http://www.physiology.org/doi/10.1152/ajpcell.00168.2012
Publisher Site
http://dx.doi.org/10.1152/ajpcell.00168.2012DOI Listing
December 2012

Plasticity-related gene-1 inhibits lysophosphatidic acid-induced vascular smooth muscle cell migration and proliferation and prevents neointima formation.

Am J Physiol Cell Physiol 2012 Nov 26;303(10):C1104-14. Epub 2012 Sep 26.

INSERM, Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche UMR_S 956, Faculté de Médecine Pitié-Salpétrière, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpcell.00051.2012DOI Listing
November 2012

KRAS mutation detection in Tunisian sporadic coloractal cancer patients with direct sequencing, high resolution melting and denaturating high performance liquid chromatography.

Cancer Biomark 2010-2011;8(6):331-40

Laboratoire de Génétique, Immunologie et Pathologies Humaines, Faculté des Sciences de Tunis, Université de Tunis El Manar, Tunisia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/CBM-2011-0222DOI Listing
March 2012

Screening for Lynch syndrome in colorectal cancer: are we doing enough?

Ann Surg Oncol 2012 Mar 31;19(3):809-16. Epub 2011 Aug 31.

Department of Digestive Surgery, Hôpital Saint-Antoine, Université Pierre et Marie Curie, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1245/s10434-011-2014-7DOI Listing
March 2012

Pulmonary arterial hypertension in a patient with Cowden syndrome and anorexigen exposure.

Chest 2011 Oct;140(4):1066-1068

Faculté de Médecine, Université Paris-Sud, Kremlin-Bicêtre, France; Service de Pneumologie et Réanimation, Centre de Référence de l'Hypertension Pulmonaire Sévère, Hôpital Antoine Béclère, Assistance Publique-Hôpitaux de Paris, Clamart, France; INSERM U999, Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique, Centre Chirurgical Marie-Lannelongue, Le Plessis-Robinson, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1378/chest.10-2588DOI Listing
October 2011

The Wnt/beta-catenin pathway is activated during advanced arterial aging in humans.

Aging Cell 2011 Apr 29;10(2):220-32. Epub 2010 Dec 29.

INSERM UMRS_956; UPMC Univ Paris 06, 91 boulevard de l'Hôpital, Paris Cedex 13, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1474-9726.2010.00661.xDOI Listing
April 2011

Atorvastatin prevents Plasmodium falciparum cytoadherence and endothelial damage.

Malar J 2011 Feb 28;10:52. Epub 2011 Feb 28.

INSERM, UMR S945, Université Pierre et Marie Curie-Paris 6, CHU-Pitié-Salpêtrière, 91 bd de l'Hôpital, 75013 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1475-2875-10-52DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056843PMC
February 2011

MYH biallelic mutation can inactivate the two genetic pathways of colorectal cancer by APC or MLH1 transversions.

Fam Cancer 2010 Dec;9(4):589-94

Department of Digestive Surgery, Hôpital Saint-Antoine AP-HP, University Pierre et Marie Curie Paris VI, 184 rue du Faubourg Saint-Antoine, 75571 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10689-010-9367-0DOI Listing
December 2010

A one-step prescreening for point mutations and large rearrangement in BRCA1 and BRCA2 genes using quantitative polymerase chain reaction and high-resolution melting curve analysis.

Genet Test Mol Biomarkers 2010 Oct 21;14(5):677-90. Epub 2010 Sep 21.

Laboratoire d'Oncogénétique et Angiogénétique moléculaire, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hopitaux de Paris, Université Pierre et Marie Curie, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/gtmb.2009.0183DOI Listing
October 2010

Genetics and genomics of pulmonary arterial hypertension.

J Am Coll Cardiol 2009 Jun;54(1 Suppl):S32-42

Department of Medical and Molecular Genetics, King's College London School of Medicine, Guy's Hospital, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacc.2009.04.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725550PMC
June 2009

Prevalence of mutations in APC, CTNNB1, and BRAF in Tunisian patients with sporadic colorectal cancer.

Cancer Genet Cytogenet 2008 Nov;187(1):12-8

Laboratory of Human Genetics, Immunology, and Pathology, Faculty of Sciences-Tunis, University of Tunis, Campus Universitaire, El Manar I, Tunis 2092, Tunisia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cancergencyto.2008.06.016DOI Listing
November 2008

Hypoxia-induced apelin expression regulates endothelial cell proliferation and regenerative angiogenesis.

Circ Res 2008 Aug 10;103(4):432-40. Epub 2008 Jul 10.

INSERM UMRS 525, Université Pierre et Marie Curie, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCRESAHA.108.179333DOI Listing
August 2008

Hereditary hemorrhagic telangiectasia: evidence for regional founder effects of ACVRL1 mutations in French and Italian patients.

Eur J Hum Genet 2008 Jun 20;16(6):742-9. Epub 2008 Feb 20.

Service de Génétique Moléculaire et Clinique, Hôpital Edouard Herriot, Université de Lyon, Université Lyon 1, 5 Place d'Arsonval, Lyon, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ejhg.2008.3DOI Listing
June 2008

Clinical outcomes of pulmonary arterial hypertension in carriers of BMPR2 mutation.

Am J Respir Crit Care Med 2008 Jun 20;177(12):1377-83. Epub 2008 Mar 20.

Université Paris-Sud 11, Service de Pneumologie et Réanimation Respiratoire, Hôpital Antoine-Béclère, 157 rue de la Porte de Trivaux, 92140 Clamart, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.200712-1807OCDOI Listing
June 2008

First genetic analysis in Tunisian familial adenomatous polyposis probands.

Oncol Rep 2008 May;19(5):1213-8

Laboratoire de Génétique, Immunologie et Pathologies Humaines, Faculté des Sciences de Tunis, Tunis 2092, Tunisia.

View Article

Download full-text PDF

Source
May 2008

Somatic mutation of MutYH in Tunisian patients with sporadic colorectal cancer.

J Clin Lab Anal 2007 ;21(6):372-4

Laboratoire de Génétique, Immunologie et Pathologies Humaines, Faculté des Sciences de Tunis, Campus Universitaire 2092, Tunis, Tunisia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcla.20198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649000PMC
March 2008

Do we know all there is to know about Familial Adenomatous Polyposis?

Gastroenterol Clin Biol 2007 Dec;31(12):1062-6

Laboratoire de génétique, immunologie et pathologies humaines, Faculté des sciences de Tunis, Campus universitaire, Tunis, Tunisie.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0399-8320(07)78335-5DOI Listing
December 2007

Identification of hypoxia-response element in the human endothelial nitric-oxide synthase gene promoter.

J Biol Chem 2003 Nov 8;278(47):46230-40. Epub 2003 Sep 8.

INSERM, Unit 525, Université Pierre et Marie Curie, Faculté de Médecine Pitié-Salpêtrière, 91 Boulevard de l'Hôpital, 75013 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M305420200DOI Listing
November 2003

Phorbol ester induction of angiotensin-converting enzyme transcription is mediated by Egr-1 and AP-1 in human endothelial cells via ERK1/2 pathway.

Circ Res 2002 Nov;91(10):899-906

Institut National de la Santé et de la Recherche Médicale, Unit 525, Faculté de Médecine Pitié-Sapétrière, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/01.res.0000042703.39845.b4DOI Listing
November 2002

High-resolution genetic mapping of the ACE-linked QTL influencing circulating ACE activity.

Eur J Hum Genet 2002 Sep;10(9):553-61

INSERM U 525, Faculté de médecine Pitié-Salpêtrière, Université Paris VI, 91 Bd de l'hôpital, 75013 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.ejhg.5200847DOI Listing
September 2002

Chronic graft dysfunction in renal transplant patients: potential role of plasminogen activator inhibitor type 1.

Transplantation 2002 Apr;73(8):1290-5

Service de Néphrologie A, Association Claude Bernard and INSERM U 489, Hôpital Tenon, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/00007890-200204270-00018DOI Listing
April 2002

Prospective evaluation of genetic abnormalities and telomerase expression in exfoliated urinary cells for bladder cancer detection.

J Urol 2002 Mar;167(3):1276-81

Laboratoire d'Histologie, Biologie Tumorale et Génétique Moléculaire, Service d'Urologie, Hôpital TENON, Paris, France.

View Article

Download full-text PDF

Source
March 2002