Publications by authors named "Florent Ginhoux"

100Publications

Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.

STAR Protoc 2020 Jun 3;1(1):100029. Epub 2020 Jun 3.

Shanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

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http://dx.doi.org/10.1016/j.xpro.2020.100029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580097PMC
June 2020

Modeling the Interaction between the Microenvironment and Tumor Cells in Brain Tumors.

Neuron 2020 Oct 7. Epub 2020 Oct 7.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (ASTAR), Singapore, Singapore; Shanghai Institute of Immunology, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Translational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2020.09.018DOI Listing
October 2020

Genetic models of human and mouse dendritic cell development and function.

Nat Rev Immunol 2020 Sep 9. Epub 2020 Sep 9.

Department of Pathology and Immunology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.

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http://dx.doi.org/10.1038/s41577-020-00413-xDOI Listing
September 2020

Kupffer Cell Characterization by Mass Cytometry.

Methods Mol Biol 2020 ;2164:87-99

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A∗STAR), Singapore, Singapore.

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http://dx.doi.org/10.1007/978-1-0716-0704-6_10DOI Listing
January 2020

Combinatorial Single-Cell Analyses of Granulocyte-Monocyte Progenitor Heterogeneity Reveals an Early Uni-potent Neutrophil Progenitor.

Immunity 2020 Aug 23;53(2):303-318.e5. Epub 2020 Jun 23.

Singapore Immunology Network (SIgN), A∗STAR (Agency for Science, Technology and Research), Biopolis, Singapore 138648, Singapore; School of Biological Sciences, Nanyang Technological University, Singapore 637551, Singapore; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545, Singapore; State Key Laboratory of Experimental Hematology, Institute of Hematology, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China; National Cancer Centre Singapore, Singapore 169610, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2020.06.005DOI Listing
August 2020

Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis.

Immunity 2020 Jul 17;53(1):204-216.e10. Epub 2020 Jun 17.

Shanghai Institute of Immunology, Translational Medicine Center, Shanghai General Hospital, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2020.06.004DOI Listing
July 2020

Determinants of Resident Tissue Macrophage Identity and Function.

Immunity 2020 Jun;52(6):957-970

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A(∗)STAR), 8A Biomedical Grove, Immunos Building #3-4, Biopolis, Singapore 138648, Singapore; Shanghai Institute of Immunology, Shanghai JiaoTong University School of Medicine, 280 South Chongqing Road, Shanghai 200025, China; Translational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore 169856, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2020.05.014DOI Listing
June 2020

Deciphering human macrophage development at single-cell resolution.

Nature 2020 06 20;582(7813):571-576. Epub 2020 May 20.

Key Laboratory for Regenerative Medicine of Ministry of Education, Institute of Hematology, School of Medicine, Jinan University, Guangzhou, China.

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http://dx.doi.org/10.1038/s41586-020-2316-7DOI Listing
June 2020

Towards the better understanding of myelopoiesis using single-cell technologies.

Mol Immunol 2020 May 6;122:186-192. Epub 2020 May 6.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore 138648, Singapore; Shanghai Institute of Immunology (SII), Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Singhealth Translational Immunology and Inflammation Centre (STIIC), 20 College Road, the Academia, Singapore 169856, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2020.04.020DOI Listing
May 2020

Kidney dendritic cells: fundamental biology and functional roles in health and disease.

Nat Rev Nephrol 2020 07 5;16(7):391-407. Epub 2020 May 5.

Division of Translational Immunology, III Medizinische Klinik, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1038/s41581-020-0272-yDOI Listing
July 2020

Engineered niches support the development of human dendritic cells in humanized mice.

Nat Commun 2020 04 28;11(1):2054. Epub 2020 Apr 28.

Centre for Inflammation Biology and Cancer Immunology, The Peter Gorer Department of Immmunobiology, King's College London, London, UK.

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http://dx.doi.org/10.1038/s41467-020-15937-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189247PMC
April 2020

Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling.

Nat Cell Biol 2020 05 27;22(5):546-558. Epub 2020 Apr 27.

Cancer Biology and Stem Cells Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1038/s41556-020-0505-0DOI Listing
May 2020

Reprint of: Manipulation of microbiota reveals altered callosal myelination and white matter plasticity in a model of Huntington disease.

Neurobiol Dis 2020 02 10;135:104744. Epub 2020 Jan 10.

Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A*STAR), 138648, Singapore; Department of Medicine, National University of Singapore, 117597, Singapore; Department of Physiology, National University of Singapore, 117597, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2020.104744DOI Listing
February 2020

Cross-Species Single-Cell Analysis Reveals Divergence of the Primate Microglia Program.

Cell 2019 12;179(7):1609-1622.e16

Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Signaling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany; Center for NeuroModulation, Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.11.010DOI Listing
December 2019

The coming of age of Langerhans cell histiocytosis.

Nat Immunol 2020 01;21(1):1-7

Scientific Member of the Steering Committee, Nikolas Symposia, Piraeus, Greece.

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http://dx.doi.org/10.1038/s41590-019-0558-zDOI Listing
January 2020

Understanding the Heterogeneity of Resident Liver Macrophages.

Front Immunol 2019 19;10:2694. Epub 2019 Nov 19.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (ASTAR), Singapore, Singapore.

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http://dx.doi.org/10.3389/fimmu.2019.02694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877662PMC
November 2019

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).

Authors:
Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Andreas Acs Dieter Adam Sabine Adam-Klages William W Agace Nima Aghaeepour Mübeccel Akdis Matthieu Allez Larissa Nogueira Almeida Giorgia Alvisi Graham Anderson Immanuel Andrä Francesco Annunziato Achille Anselmo Petra Bacher Cosima T Baldari Sudipto Bari Vincenzo Barnaba Joana Barros-Martins Luca Battistini Wolfgang Bauer Sabine Baumgart Nicole Baumgarth Dirk Baumjohann Bianka Baying Mary Bebawy Burkhard Becher Wolfgang Beisker Vladimir Benes Rudi Beyaert Alfonso Blanco Dominic A Boardman Christian Bogdan Jessica G Borger Giovanna Borsellino Philip E Boulais Jolene A Bradford Dirk Brenner Ryan R Brinkman Anna E S Brooks Dirk H Busch Martin Büscher Timothy P Bushnell Federica Calzetti Garth Cameron Ilenia Cammarata Xuetao Cao Susanna L Cardell Stefano Casola Marco A Cassatella Andrea Cavani Antonio Celada Lucienne Chatenoud Pratip K Chattopadhyay Sue Chow Eleni Christakou Luka Čičin-Šain Mario Clerici Federico S Colombo Laura Cook Anne Cooke Andrea M Cooper Alexandra J Corbett Antonio Cosma Lorenzo Cosmi Pierre G Coulie Ana Cumano Ljiljana Cvetkovic Van Duc Dang Chantip Dang-Heine Martin S Davey Derek Davies Sara De Biasi Genny Del Zotto Gelo Victoriano Dela Cruz Michael Delacher Silvia Della Bella Paolo Dellabona Günnur Deniz Mark Dessing James P Di Santo Andreas Diefenbach Francesco Dieli Andreas Dolf Thomas Dörner Regine J Dress Diana Dudziak Michael Dustin Charles-Antoine Dutertre Friederike Ebner Sidonia B G Eckle Matthias Edinger Pascale Eede Götz R A Ehrhardt Marcus Eich Pablo Engel Britta Engelhardt Anna Erdei Charlotte Esser Bart Everts Maximilien Evrard Christine S Falk Todd A Fehniger Mar Felipo-Benavent Helen Ferry Markus Feuerer Andrew Filby Kata Filkor Simon Fillatreau Marie Follo Irmgard Förster John Foster Gemma A Foulds Britta Frehse Paul S Frenette Stefan Frischbutter Wolfgang Fritzsche David W Galbraith Anastasia Gangaev Natalio Garbi Brice Gaudilliere Ricardo T Gazzinelli Jens Geginat Wilhelm Gerner Nicholas A Gherardin Kamran Ghoreschi Lara Gibellini Florent Ginhoux Keisuke Goda Dale I Godfrey Christoph Goettlinger Jose M González-Navajas Carl S Goodyear Andrea Gori Jane L Grogan Daryl Grummitt Andreas Grützkau Claudia Haftmann Jonas Hahn Hamida Hammad Günter Hämmerling Leo Hansmann Goran Hansson Christopher M Harpur Susanne Hartmann Andrea Hauser Anja E Hauser David L Haviland David Hedley Daniela C Hernández Guadalupe Herrera Martin Herrmann Christoph Hess Thomas Höfer Petra Hoffmann Kristin Hogquist Tristan Holland Thomas Höllt Rikard Holmdahl Pleun Hombrink Jessica P Houston Bimba F Hoyer Bo Huang Fang-Ping Huang Johanna E Huber Jochen Huehn Michael Hundemer Christopher A Hunter William Y K Hwang Anna Iannone Florian Ingelfinger Sabine M Ivison Hans-Martin Jäck Peter K Jani Beatriz Jávega Stipan Jonjic Toralf Kaiser Tomas Kalina Thomas Kamradt Stefan H E Kaufmann Baerbel Keller Steven L C Ketelaars Ahad Khalilnezhad Srijit Khan Jan Kisielow Paul Klenerman Jasmin Knopf Hui-Fern Koay Katja Kobow Jay K Kolls Wan Ting Kong Manfred Kopf Thomas Korn Katharina Kriegsmann Hendy Kristyanto Thomas Kroneis Andreas Krueger Jenny Kühne Christian Kukat Désirée Kunkel Heike Kunze-Schumacher Tomohiro Kurosaki Christian Kurts Pia Kvistborg Immanuel Kwok Jonathan Landry Olivier Lantz Paola Lanuti Francesca LaRosa Agnès Lehuen Salomé LeibundGut-Landmann Michael D Leipold Leslie Y T Leung Megan K Levings Andreia C Lino Francesco Liotta Virginia Litwin Yanling Liu Hans-Gustaf Ljunggren Michael Lohoff Giovanna Lombardi Lilly Lopez Miguel López-Botet Amy E Lovett-Racke Erik Lubberts Herve Luche Burkhard Ludewig Enrico Lugli Sebastian Lunemann Holden T Maecker Laura Maggi Orla Maguire Florian Mair Kerstin H Mair Alberto Mantovani Rudolf A Manz Aaron J Marshall Alicia Martínez-Romero Glòria Martrus Ivana Marventano Wlodzimierz Maslinski Giuseppe Matarese Anna Vittoria Mattioli Christian Maueröder Alessio Mazzoni James McCluskey Mairi McGrath Helen M McGuire Iain B McInnes Henrik E Mei Fritz Melchers Susanne Melzer Dirk Mielenz Stephen D Miller Kingston H G Mills Hans Minderman Jenny Mjösberg Jonni Moore Barry Moran Lorenzo Moretta Tim R Mosmann Susann Müller Gabriele Multhoff Luis Enrique Muñoz Christian Münz Toshinori Nakayama Milena Nasi Katrin Neumann Lai Guan Ng Antonia Niedobitek Sussan Nourshargh Gabriel Núñez José-Enrique O'Connor Aaron Ochel Anna Oja Diana Ordonez Alberto Orfao Eva Orlowski-Oliver Wenjun Ouyang Annette Oxenius Raghavendra Palankar Isabel Panse Kovit Pattanapanyasat Malte Paulsen Dinko Pavlinic Livius Penter Pärt Peterson Christian Peth Jordi Petriz Federica Piancone Winfried F Pickl Silvia Piconese Marcello Pinti A Graham Pockley Malgorzata Justyna Podolska Zhiyong Poon Katharina Pracht Immo Prinz Carlo E M Pucillo Sally A Quataert Linda Quatrini Kylie M Quinn Helena Radbruch Tim R D J Radstake Susann Rahmig Hans-Peter Rahn Bartek Rajwa Gevitha Ravichandran Yotam Raz Jonathan A Rebhahn Diether Recktenwald Dorothea Reimer Caetano Reis e Sousa Ester B M Remmerswaal Lisa Richter Laura G Rico Andy Riddell Aja M Rieger J Paul Robinson Chiara Romagnani Anna Rubartelli Jürgen Ruland Armin Saalmüller Yvan Saeys Takashi Saito Shimon Sakaguchi Francisco Sala-de-Oyanguren Yvonne Samstag Sharon Sanderson Inga Sandrock Angela Santoni Ramon Bellmàs Sanz Marina Saresella Catherine Sautes-Fridman Birgit Sawitzki Linda Schadt Alexander Scheffold Hans U Scherer Matthias Schiemann Frank A Schildberg Esther Schimisky Andreas Schlitzer Josephine Schlosser Stephan Schmid Steffen Schmitt Kilian Schober Daniel Schraivogel Wolfgang Schuh Thomas Schüler Reiner Schulte Axel Ronald Schulz Sebastian R Schulz Cristiano Scottá Daniel Scott-Algara David P Sester T Vincent Shankey Bruno Silva-Santos Anna Katharina Simon Katarzyna M Sitnik Silvano Sozzani Daniel E Speiser Josef Spidlen Anders Stahlberg Alan M Stall Natalie Stanley Regina Stark Christina Stehle Tobit Steinmetz Hannes Stockinger Yousuke Takahama Kiyoshi Takeda Leonard Tan Attila Tárnok Gisa Tiegs Gergely Toldi Julia Tornack Elisabetta Traggiai Mohamed Trebak Timothy I M Tree Joe Trotter John Trowsdale Maria Tsoumakidou Henning Ulrich Sophia Urbanczyk Willem van de Veen Maries van den Broek Edwin van der Pol Sofie Van Gassen Gert Van Isterdael René A W van Lier Marc Veldhoen Salvador Vento-Asturias Paulo Vieira David Voehringer Hans-Dieter Volk Anouk von Borstel Konrad von Volkmann Ari Waisman Rachael V Walker Paul K Wallace Sa A Wang Xin M Wang Michael D Ward Kirsten A Ward-Hartstonge Klaus Warnatz Gary Warnes Sarah Warth Claudia Waskow James V Watson Carsten Watzl Leonie Wegener Thomas Weisenburger Annika Wiedemann Jürgen Wienands Anneke Wilharm Robert John Wilkinson Gerald Willimsky James B Wing Rieke Winkelmann Thomas H Winkler Oliver F Wirz Alicia Wong Peter Wurst Jennie H M Yang Juhao Yang Maria Yazdanbakhsh Liping Yu Alice Yue Hanlin Zhang Yi Zhao Susanne Maria Ziegler Christina Zielinski Jakob Zimmermann Arturo Zychlinsky

Eur J Immunol 2019 Oct;49(10):1457-1973

Max Planck Institute for Infection Biology, Berlin, Germany.

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http://dx.doi.org/10.1002/eji.201970107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350392PMC
October 2019

Constitutive Siglec-1 expression confers susceptibility to HIV-1 infection of human dendritic cell precursors.

Proc Natl Acad Sci U S A 2019 10 7;116(43):21685-21693. Epub 2019 Oct 7.

Institut Curie, Paris Sciences et Lettres (PSL*) Research University, INSERM U932, Paris, France;

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http://dx.doi.org/10.1073/pnas.1911007116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815136PMC
October 2019

Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells.

Cell 2019 09;178(6):1509-1525.e19

Shanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore 138648, Singapore; Translational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.08.009DOI Listing
September 2019

Single-Cell Analysis of Human Mononuclear Phagocytes Reveals Subset-Defining Markers and Identifies Circulating Inflammatory Dendritic Cells.

Immunity 2019 09 29;51(3):573-589.e8. Epub 2019 Aug 29.

Singapore Immunology Network, A(∗)STAR, 8A Biomedical Grove, Immunos Building, Singapore 138648, Singapore; Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre, the Academia, 20 College Road, Discovery Tower Level 8, Singapore 169856, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.08.008DOI Listing
September 2019

TCR Sequencing Reveals the Distinct Development of Fetal and Adult Human Vγ9Vδ2 T Cells.

J Immunol 2019 09 14;203(6):1468-1479. Epub 2019 Aug 14.

Department of Pharmacotherapy and Pharmaceutics, Université Libre de Bruxelles (ULB), 1050 Brussels, Belgium;

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http://dx.doi.org/10.4049/jimmunol.1900592DOI Listing
September 2019

Novel Microglia Depletion Systems: A Genetic Approach Utilizing Conditional Diphtheria Toxin Receptor Expression and a Pharmacological Model Based on the Blocking of Macrophage Colony-Stimulating Factor 1 Receptor.

Methods Mol Biol 2019 ;2034:217-230

Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg University of Mainz, Mainz, Germany.

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http://dx.doi.org/10.1007/978-1-4939-9658-2_16DOI Listing
April 2020

Biphasic Impact of Prenatal Inflammation and Macrophage Depletion on the Wiring of Neocortical Inhibitory Circuits.

Cell Rep 2019 07;28(5):1119-1126.e4

Neurophysiologie et Nouvelles Microscopies, INSERM U1128, Université Paris Descartes, 75006 Paris, France; Institut de Génomique Fonctionnelle (IGF), CNRS, INSERM, Université de Montpellier, 34094 Montpellier, France. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.06.086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685496PMC
July 2019

Cell-autonomous FLT3L shedding via ADAM10 mediates conventional dendritic cell development in mouse spleen.

Proc Natl Acad Sci U S A 2019 07 1;116(29):14714-14723. Epub 2019 Jul 1.

Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892;

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http://dx.doi.org/10.1073/pnas.1818907116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642353PMC
July 2019

Perturbation of the immune cells and prenatal neurogenesis by the triplication of the Erg gene in mouse models of Down syndrome.

Brain Pathol 2020 01 4;30(1):75-91. Epub 2019 Jul 4.

Department of Pathological Biochemistry, Division of Pathological Sciences, Kyoto Pharmaceutical University, Kyoto, Japan.

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http://dx.doi.org/10.1111/bpa.12758DOI Listing
January 2020

Visualizing Microglia with a Fluorescence Turn-On Ugt1a7c Substrate.

Angew Chem Int Ed Engl 2019 06 30;58(24):7972-7976. Epub 2019 Apr 30.

Department of Chemistry, Pohang University of Science and Technology, Pohang, 37673, Korea.

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http://dx.doi.org/10.1002/anie.201903058DOI Listing
June 2019

"Cloaking" on Time: A Cover-Up Act by Resident Tissue Macrophages.

Cell 2019 04;177(3):514-516

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A∗STAR), 8A Biomedical Grove, Immunos Building #3-4, Biopolis, Singapore 138648, Singapore; Shanghai Institute of Immunology, Shanghai JiaoTong University School of Medicine, 280 South Chongqing Road, Shanghai 200025, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674193034
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http://dx.doi.org/10.1016/j.cell.2019.03.042DOI Listing
April 2019

A Subset of Type I Conventional Dendritic Cells Controls Cutaneous Bacterial Infections through VEGFα-Mediated Recruitment of Neutrophils.

Immunity 2019 04 27;50(4):1069-1083.e8. Epub 2019 Mar 27.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A(∗)STAR), 8A Biomedical Grove, Biopolis, Singapore 138648, Singapore; Skin Research Institute of Singapore (SRIS), Agency for Science, Technology and Research (A(∗)STAR), 11 Mandalay Rd., Singapore 308232, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.03.001DOI Listing
April 2019

Corrigendum: A Single-Cell Sequencing Guide for Immunologists.

Front Immunol 2019 26;10:278. Epub 2019 Feb 26.

Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.

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http://dx.doi.org/10.3389/fimmu.2019.00278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400142PMC
February 2019

Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects.

Cell Rep 2019 02;26(9):2494-2508.e7

Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A(∗)STAR), Singapore 138648, Singapore; Department of Medicine, National University of Singapore (NUS), Singapore 117597, Singapore; Department of Physiology, National University of Singapore (NUS), Singapore 117597, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.02.008DOI Listing
February 2019

Manipulation of microbiota reveals altered callosal myelination and white matter plasticity in a model of Huntington disease.

Neurobiol Dis 2019 07 23;127:65-75. Epub 2019 Feb 23.

Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A*STAR), 138648, Singapore; Department of Medicine, National University of Singapore, 117597, Singapore; Department of Physiology, National University of Singapore, 117597, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2019.02.011DOI Listing
July 2019

Identification of CD39 as a Marker for the Circulating Malignant T-Cell Clone of Sézary Syndrome Patients.

J Invest Dermatol 2019 03 25;139(3):725-728. Epub 2018 Oct 25.

INSERM U976, Oncodermatology, Immunology and Cutaneous stem cells, Paris, France; University Paris Diderot, Sorbonne Paris Cité, Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0022202X183269
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http://dx.doi.org/10.1016/j.jid.2018.09.026DOI Listing
March 2019

Fat-fated microglial dysfunction.

EMBO J 2019 01 19;38(2). Epub 2018 Dec 19.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore.

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http://dx.doi.org/10.15252/embj.2018101176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331718PMC
January 2019

Dimensionality reduction for visualizing single-cell data using UMAP.

Nat Biotechnol 2018 Dec 3. Epub 2018 Dec 3.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.

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http://www.nature.com/doifinder/10.1038/nbt.4314
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http://dx.doi.org/10.1038/nbt.4314DOI Listing
December 2018

, from the Academic Editors.

Life Sci Alliance 2018 Jan 20;1(1):e201800044. Epub 2018 Mar 20.

Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://www.life-science-alliance.org/lookup/doi/10.26508/lsa
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http://dx.doi.org/10.26508/lsa.201800044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246889PMC
January 2018

Ezh2 Controls Skin Tolerance through Distinct Mechanisms in Different Subsets of Skin Dendritic Cells.

iScience 2018 Dec 14;10:23-39. Epub 2018 Nov 14.

School of Biological Sciences, College of Science, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551, Republic of Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2018.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260444PMC
December 2018

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes.

Immunity 2019 01 21;50(1):253-271.e6. Epub 2018 Nov 21.

Boston Children's Hospital, F.M. Kirby Neurobiology Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613183048
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http://dx.doi.org/10.1016/j.immuni.2018.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6655561PMC
January 2019

The immunological anatomy of the skin.

Nat Rev Immunol 2019 01;19(1):19-30

Department of Dermatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1038/s41577-018-0084-5DOI Listing
January 2019

Epidermal γδ T cells originate from yolk sac hematopoiesis and clonally self-renew in the adult.

J Exp Med 2018 12 8;215(12):2994-3005. Epub 2018 Nov 8.

Aix-Marseille University, Centre National de la Recherche Scientifique, Institut National de la Santé et de la Recherche Médicale, Centre d'Immunologie de Marseille-Luminy, Marseille, France

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http://dx.doi.org/10.1084/jem.20181206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279412PMC
December 2018

A Single-Cell Sequencing Guide for Immunologists.

Front Immunol 2018 23;9:2425. Epub 2018 Oct 23.

Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02425
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http://dx.doi.org/10.3389/fimmu.2018.02425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205970PMC
September 2019

Microglia and early brain development: An intimate journey.

Science 2018 10;362(6411):185-189

Institut de Biologie de l'École Normale Supérieure (IBENS), École Normale Supérieure, CNRS, INSERM, PSL Université Paris, 75005 Paris, France.

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http://www.sciencemag.org/lookup/doi/10.1126/science.aat0474
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October 2018

Embryonic macrophages and microglia ablation alter the development of dorsal root ganglion sensory neurons in mouse embryos.

Glia 2018 11 25;66(11):2470-2486. Epub 2018 Sep 25.

Sorbonne Université, UPMC Univ Paris 06, INSERM, CNRS, Neurosciences Paris Seine, Institut de Biologie Paris Seine (NPS, IBPS), Paris, France.

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http://doi.wiley.com/10.1002/glia.23499
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November 2018

Publisher Correction: Studying tissue macrophages in vitro: are iPSC-derived cells the answer?

Nat Rev Immunol 2018 Nov;18(11):726

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore.

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November 2018

Microglia heterogeneity along a spatio-temporal axis: More questions than answers.

Glia 2018 10 25;66(10):2045-2057. Epub 2018 Aug 25.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, IMMUNOS Building #3-4, BIOPOLIS, 138648, Singapore.

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http://doi.wiley.com/10.1002/glia.23458
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October 2018

Studying tissue macrophages in vitro: are iPSC-derived cells the answer?

Nat Rev Immunol 2018 11;18(11):716-725

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), BIOPOLIS, Singapore, Singapore.

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http://www.nature.com/articles/s41577-018-0054-y
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November 2018

Editorial for Cellular Immunology special issue on "Tissue Macrophages".

Cell Immunol 2018 08;330:1-4

Unit of Immunoregulation and Mucosal Immunology, VIB Inflammation Research Center, Ghent, 9052, Belgium; Department of Biomedical Molecular Biology, Ghent University, Ghent 9000, Belgium. Electronic address:

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August 2018

Macrophage depletion in cancer therapy: A double-edged sword.

Cell Immunol 2018 09 1;331:178-179. Epub 2018 Aug 1.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos Building #3-4, Biopolis, Singapore 138648, Singapore. Electronic address:

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September 2018

The mysterious origins of microglia.

Nat Neurosci 2018 07;21(7):897-899

Institut de Biologie de l'École Normale Supérieure (IBENS), École Normale Supérieure, CNRS, INSERM, PSL Université Paris, Paris, France.

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July 2018

Hemogenic Endothelial Fate Mapping Reveals Dual Developmental Origin of Mast Cells.

Immunity 2018 06 29;48(6):1160-1171.e5. Epub 2018 May 29.

Aix-Marseille University, Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM), Centre d'Immunologie de Marseille-Luminy (CIML), Marseille, France. Electronic address:

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June 2018

Human dendritic cells.

Semin Cell Dev Biol 2019 02 19;86:1-2. Epub 2018 May 19.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove IMMUNOS bldg, Level 3, SINGAPORE 138648. Electronic address:

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February 2019

Bevacizumab Promotes T-Cell-Mediated Collagen Deposition in the Mouse Model of Conjunctival Scarring.

Invest Ophthalmol Vis Sci 2018 03;59(3):1682-1692

Singapore Eye Research Institute, Singapore.

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March 2018

Fetal monocytes and the origins of tissue-resident macrophages.

Cell Immunol 2018 08 12;330:5-15. Epub 2018 Jan 12.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, IMMUNOS Building #3-4, BIOPOLIS, 138648, Singapore; Shanghai Institute of Immunology, Shanghai JiaoTong University School of Medicine, 280 South Chongqing Road, Shanghai 200025, China. Electronic address:

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August 2018

Homeostatic control of dendritic cell numbers and differentiation.

Immunol Cell Biol 2018 05 23;96(5):463-476. Epub 2018 Mar 23.

Singapore Immunology Network (SIgN), Agency for Science, Technology, and Research (A*STAR), Singapore, 138648, Singapore.

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May 2018

Recent advances in the understanding of microglial development and homeostasis.

Cell Immunol 2018 08 10;330:68-78. Epub 2018 Jan 10.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore; Shanghai Institute of Immunology, Shanghai JiaoTong University School of Medicine, 280 South Chongqing Road, Shanghai 200025, China. Electronic address:

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August 2018

Blood-brain barrier development: Systems modeling and predictive toxicology.

Birth Defects Res 2017 Dec;109(20):1680-1710

National Center for Computational Toxicology (NCCT); U.S. Environmental Protection Agency, Office of Research and Development, Research Triangle Park, North Carolina 27711.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476421PMC
December 2017

Constructing cell lineages from single-cell transcriptomes.

Mol Aspects Med 2018 02 26;59:95-113. Epub 2017 Nov 26.

Singapore Immunology Network (SIgN), A*STAR, 8A Biomedical Grove, Immunos Building, Level 4, Singapore 138648, Singapore.

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February 2018

New beginnings.

Authors:
Florent Ginhoux

Nat Rev Immunol 2017 12 30;17(12):732. Epub 2017 Oct 30.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), SINGAPORE 138648.

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http://www.nature.com/doifinder/10.1038/nri.2017.91
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December 2017