Florence Pedeutour

Florence Pedeutour

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Florence Pedeutour

Publications by authors named "Florence Pedeutour"

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Double minute chromosomes harboring MDM2 amplification in a pediatric atypical lipomatous tumor.

Genes Chromosomes Cancer 2019 09 13;58(9):673-679. Epub 2019 Apr 13.

Laboratory of Solid Tumors Genetics, Institute for Research on Cancer and Aging of Nice (IRCAN), CNRS UMR 7284/INSERM U1081, Université Côte d'Azur (UCA), Centre Hospitalier Universitaire de Nice, Faculté de Médecine, Nice, France.

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http://dx.doi.org/10.1002/gcc.22754DOI Listing
September 2019

Microsatellite instability associated with durable complete response to PD-L1 inhibitor in head and neck squamous cell carcinoma.

Oral Oncol 2018 05 7;80:104-107. Epub 2018 Apr 7.

Department of Medical Oncology, Centre Antoine Lacassagne, Cancer Research Center, 33 avenue de Valombrose, 06189 Nice cedex 2, France; Oncopharmacology Unit, Centre Antoine Lacassagne, Cancer Research Center, 33 avenue de Valombrose, 06189 Nice cedex 2, France. Electronic address:

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http://dx.doi.org/10.1016/j.oraloncology.2018.04.001DOI Listing
May 2018

Comprehensive study of three novel cases of TFEB-amplified renal cell carcinoma and review of the literature: Evidence for a specific entity with poor outcome.

Genes Chromosomes Cancer 2018 03 20;57(3):99-113. Epub 2017 Dec 20.

Laboratory of Solid Tumor Genetics, Institute for Research on Cancer and Aging of Nice (IRCAN), CNRS UMR 7284/INSERM U1081, Nice, France.

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http://dx.doi.org/10.1002/gcc.22513DOI Listing
March 2018

ALK-TPM3 rearrangement in adult renal cell carcinoma: Report of a new case showing loss of chromosome 3 and literature review.

Cancer Genet 2018 02 12;221:31-37. Epub 2017 Dec 12.

Laboratory of Solid Tumor Genetics, Institute for Research on Cancer and Aging of Nice (IRCAN), CNRS UMR 7284/INSERM U1081, Nice, France; Laboratory of Solid Tumor Genetics, University Hospital of Nice-Côte d'Azur University, Nice, France. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2017.11.010DOI Listing
February 2018

Congenital Infantile Fibrosarcoma Associated With a Lipofibromatosis-Like Component: One Train May Be Hiding Another.

Am J Dermatopathol 2017 Jun;39(6):463-467

Departments of *Maxillofacial and Plastic Surgery, and †Pathology, Necker Children Hospital, APHP, Paris, France; ‡Paris Descartes University, Paris, France; Departments of §Pediatric Radiology, and ¶Dermatology, Necker Children Hospital, APHP, Paris, France; ‖Laboratory of Solid Tumors Genetics and Central Laboratory of Pathology, Nice University Hospital, Nice, France; **Microenvironment, Signaling and Cancer, INSERM, Université Nice Sophia-Antipolis, Nice, France; ††Molecular Oral Pathology, INSERM, Centre de Recherche de Cordeliers, Paris, France; and ‡‡Adolescent and Pediatric Oncology Department, Institut Curie, Paris, France.

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http://dx.doi.org/10.1097/DAD.0000000000000696DOI Listing
June 2017

Peritoneal carcinomatosis of colorectal cancer: novel clinical and molecular outcomes.

Am J Surg 2017 Feb 5;213(2):377-387. Epub 2016 Aug 5.

Department of General Surgery and Digestive Cancerology, Nice University Hospital, 151 route de St. Antoine de Ginestière, Nice, 06200, France.

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http://dx.doi.org/10.1016/j.amjsurg.2016.03.008DOI Listing
February 2017

Challenging a dogma: co-mutations exist in MAPK pathway genes in colorectal cancer.

Virchows Arch 2016 Oct 11;469(4):459-64. Epub 2016 Jul 11.

Molecular Pathology Unit, Institut Bergonié, 229 Cours de L'Argonne, 33076, Bordeaux, France.

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http://dx.doi.org/10.1007/s00428-016-1991-0DOI Listing
October 2016

Clinical effect of molecular methods in sarcoma diagnosis (GENSARC): a prospective, multicentre, observational study.

Lancet Oncol 2016 Apr 10;17(4):532-538. Epub 2016 Mar 10.

Laboratory of Solid Tumor Genetics, Nice University Hospital, Nice, France; Institute for Research on Cancer and Aging of Nice (IRCAN), Faculty of Medicine, University of Nice-Sophia-Antipolis, CNRS, Nice, France.

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http://dx.doi.org/10.1016/S1470-2045(15)00583-5DOI Listing
April 2016

Molecular cytogenetics of pediatric adipocytic tumors.

Cancer Genet 2015 Oct 26;208(10):469-81. Epub 2015 Jun 26.

Laboratory of Solid Tumors Genetics, Nice University Hospital, Faculty of Medicine, Nice, France; Institute for Research on Cancer and Aging of Nice (IRCAN), CNRS UMR 7284/INSERM U1081, University of Nice - Sophia Antipolis, Faculty of Medicine, Nice, France. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2015.06.005DOI Listing
October 2015

Dismantling papillary renal cell carcinoma classification: The heterogeneity of genetic profiles suggests several independent diseases.

Genes Chromosomes Cancer 2015 Jun 28;54(6):369-82. Epub 2015 Mar 28.

Institute for Research on Cancer and Aging of Nice (IRCAN), CNRS UMR 7284/INSERM U1081, University of Nice-Sophia Antipolis, Nice, France; Department of Urology, Nice University Hospital, Nice, France.

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http://dx.doi.org/10.1002/gcc.22248DOI Listing
June 2015

Fluorescence in situ hybridization analysis is a helpful test for the diagnosis of dermatofibrosarcoma protuberans.

Mod Pathol 2015 Feb 1;28(2):230-7. Epub 2014 Aug 1.

1] Department of Pathology, Institut Bergonié, Bordeaux, France [2] INSERM U916, Bordeaux, France [3] Université de Bordeaux, Bordeaux, France.

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http://dx.doi.org/10.1038/modpathol.2014.97DOI Listing
February 2015

Syndecan-1 regulates adipogenesis: new insights in dedifferentiated liposarcoma tumorigenesis.

Carcinogenesis 2015 Jan 24;36(1):32-40. Epub 2014 Oct 24.

Institute for Research on Cancer and Aging of Nice, CNRS UMR 7284/INSERM U1081, University of Nice-Sophia Antipolis, 06107 Nice, France,

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http://dx.doi.org/10.1093/carcin/bgu222DOI Listing
January 2015

The architecture and evolution of cancer neochromosomes.

Cancer Cell 2014 Nov 10;26(5):653-67. Epub 2014 Nov 10.

Cancer Genomics, Peter MacCallum Cancer Centre, East Melbourne, VIC 3002, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, VIC 3010, Australia; The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia. Electronic address:

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http://www.cell.com/cms/attachment/2020782748/2040814140/mmc
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http://linkinghub.elsevier.com/retrieve/pii/S153561081400373
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http://dx.doi.org/10.1016/j.ccell.2014.09.010DOI Listing
November 2014

Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability.

Cancer Res 2013 Jul 23;73(14):4311-22. Epub 2013 May 23.

Institute of Research on Cancer and Ageing of Nice (IRCAN), INSERM U1081, CNRS UMR7284, Laboratoire TIRO-MATOs UMR E4320, Commissariat à l'Energie Atomique, Centre Antoine Lacassagne, Avenue de Valombrose; 06107 Nice Cedex 02, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-4142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740229PMC
July 2013

Identification of PPAP2B as a novel recurrent translocation partner gene of HMGA2 in lipomas.

Genes Chromosomes Cancer 2013 Jun 18;52(6):580-90. Epub 2013 Mar 18.

Laboratory of Solid Tumors Genetics, Nice University Hospital, Institute for Research on Cancer and Aging of Nice (IRCAN), CNRS UMR 7284/INSERM U1081, University of Nice-Sophia Antipolis, Nice, France.

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http://dx.doi.org/10.1002/gcc.22055DOI Listing
June 2013

EGFR mutation status in brain metastases of non-small cell lung carcinoma.

J Neurooncol 2013 Jan 20;111(1):1-10. Epub 2012 Oct 20.

Department of Pathology, University Hospital of Nice, Nice, France.

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http://dx.doi.org/10.1007/s11060-012-0990-5DOI Listing
January 2013

SMARCB1/INI1 inactivation in renal medullary carcinoma.

Histopathology 2012 Sep 11;61(3):428-35. Epub 2012 Jun 11.

AP-HP, Département de Pathologie, Hôpital H. Mondor - A. Chenevier, Créteil, France.

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http://dx.doi.org/10.1111/j.1365-2559.2012.04228.xDOI Listing
September 2012

Rearrangement of HMGA2 in a case of infantile lipoblastoma without Plag1 alteration.

Pediatr Blood Cancer 2012 May 6;58(5):798-800. Epub 2012 Jan 6.

University of Nice-Sophia-Antipolis, CNRS, UMR 6543, Nice, France.

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http://doi.wiley.com/10.1002/pbc.23335
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http://dx.doi.org/10.1002/pbc.23335DOI Listing
May 2012

Dermatofibrosarcoma protuberans-derived fibrosarcoma: clinical history, biological profile and sensitivity to imatinib.

Int J Cancer 2011 Oct 8;129(7):1761-72. Epub 2011 Mar 8.

Adult Sarcoma Medical Oncology Unit, Department of Cancer Medicine, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.

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http://dx.doi.org/10.1002/ijc.25826DOI Listing
October 2011

Plexiform fibrohistiocytic tumor with molecular and cytogenetic analysis.

Pediatr Dermatol 2011 Jan-Feb;28(1):26-9. Epub 2011 Jan 25.

Departments of Pathology, Necker-Enfants Malades Hospital, APHP, Paris, France.

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http://dx.doi.org/10.1111/j.1525-1470.2010.01370.xDOI Listing
June 2011

CCND1 and MET genomic amplification during malignant transformation of a giant cell tumor of bone.

J Clin Oncol 2011 Feb 22;29(4):e86-9. Epub 2010 Nov 22.

Laboratory of Solid Tumors Genetics, Nice University Hospital, and Faculty of Medicine, University of Nice Sophia-Antipolis, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 6543, Nice, France.

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http://dx.doi.org/10.1200/JCO.2010.31.4286DOI Listing
February 2011

Well-differentiated and dedifferentiated liposarcomas.

Virchows Arch 2010 Feb 18;456(2):167-79. Epub 2009 Aug 18.

Department of Pathology and INSERM U916, Institut Bergonié, Bordeaux, France.

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http://link.springer.com/10.1007/s00428-009-0815-x
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http://dx.doi.org/10.1007/s00428-009-0815-xDOI Listing
February 2010

Oncocytic lipoadenoma of the parotid gland: Immunohistochemical and cytogenetic analysis.

Pathol Res Pract 2010 Jan 5;206(1):66-72. Epub 2009 Apr 5.

Laboratory of Clinical and Experimental Pathology, 30 Avenue de la Voie Romaine, Louis Pasteur Hospital, 06002 Nice, France.

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http://linkinghub.elsevier.com/retrieve/pii/S034403380900069
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http://dx.doi.org/10.1016/j.prp.2009.02.008DOI Listing
January 2010

Selective elimination of amplified CDK4 sequences correlates with spontaneous adipocytic differentiation in liposarcoma.

Genes Chromosomes Cancer 2009 Nov;48(11):943-52

Institut Curie, Genetics and Biology of Cancers, 26 rue d'Ulm, 75248 Paris cedex 05, France.

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http://doi.wiley.com/10.1002/gcc.20696
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http://dx.doi.org/10.1002/gcc.20696DOI Listing
November 2009

Fusion of EWSR1 with the DUX4 facioscapulohumeral muscular dystrophy region resulting from t(4;22)(q35;q12) in a case of embryonal rhabdomyosarcoma.

Cancer Genet Cytogenet 2009 Nov;195(1):12-8

Laboratory of Solid Tumor Genetics, Nice University Hospital, 06107 Nice, France.

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http://dx.doi.org/10.1016/j.cancergencyto.2009.06.011DOI Listing
November 2009

HMGA2-NFIB fusion in a pediatric intramuscular lipoma: a novel case of NFIB alteration in a large deep-seated adipocytic tumor.

Cancer Genet Cytogenet 2009 Nov;195(1):66-70

Faculty of Medicine, Laboratory of Solid Tumor Genetics, Nice University Hospital, 06107 Nice cedex 2, France.

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https://linkinghub.elsevier.com/retrieve/pii/S01654608090032
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http://dx.doi.org/10.1016/j.cancergencyto.2009.06.009DOI Listing
November 2009

Other targetable sarcomas.

Semin Oncol 2009 Aug;36(4):358-71

Sarcoma Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1053/j.seminoncol.2009.06.008DOI Listing
August 2009

Variability of origin for the neocentromeric sequences in analphoid supernumerary marker chromosomes of well-differentiated liposarcomas.

Cancer Lett 2009 Jan 26;273(2):323-30. Epub 2008 Sep 26.

Laboratory of Solid Tumors Genetics, Nice University Hospital and CNRS UMR 6543, Faculty of Medicine, 28 avenue de Valombrose, 06107 Nice, France.

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http://linkinghub.elsevier.com/retrieve/pii/S030438350800655
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http://dx.doi.org/10.1016/j.canlet.2008.08.025DOI Listing
January 2009

NFIB rearrangement in superficial, retroperitoneal, and colonic lipomas with aberrations involving chromosome band 9p22.

Genes Chromosomes Cancer 2008 Nov;47(11):971-7

Laboratory of Solid Tumors Genetics, Nice University Hospital, Nice, France.

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http://dx.doi.org/10.1002/gcc.20602DOI Listing
November 2008

Monosomy 7 and absence of 12q amplification in two cases of spindle cell liposarcomas.

Cancer Genet Cytogenet 2008 Jul;184(2):99-104

Laboratory of Solid Tumors Genetics, Faculty of Medicine, Nice University Hospital, 28 avenue de Valombrose, 06107 Nice, France.

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http://dx.doi.org/10.1016/j.cancergencyto.2008.04.004DOI Listing
July 2008

Complex t(5;8) involving the CSPG2 and PTK2B genes in a case of dermatofibrosarcoma protuberans without the COL1A1-PDGFB fusion.

Virchows Arch 2008 Jun 6;452(6):689-96. Epub 2008 Feb 6.

Laboratoire de Génétique des Tumeurs Solides, Faculté de Médecine, Centre Hospitalier Universitaire de Nice, Université de Nice-Sophia Antipolis, Nice, France.

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http://dx.doi.org/10.1007/s00428-008-0580-2DOI Listing
June 2008

Episomal amplification of MYCN in a case of medulloblastoma.

Virchows Arch 2008 May;452(5):491-7

Department of Genetics and Microbiology, University of Bari, Bari, Italy.

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http://dx.doi.org/10.1007/s00428-008-0592-yDOI Listing
May 2008

Detection of the TMPRSS2-ETS fusion gene in prostate carcinomas: retrospective analysis of 55 formalin-fixed and paraffin-embedded samples with clinical data.

Cancer Genet Cytogenet 2008 May;183(1):21-7

Laboratory of Solid Tumors Genetics, Nice University Hospital and CNRS UMR 6543, Faculty of Medicine, 28 avenue de Valombrose, 06107 Nice, France.

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http://linkinghub.elsevier.com/retrieve/pii/S016546080800097
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http://dx.doi.org/10.1016/j.cancergencyto.2008.01.021DOI Listing
May 2008

Ovarian dysgerminoma and Apert syndrome.

Pediatr Blood Cancer 2008 Mar;50(3):696-8

Laboratory of Solid Tumors Genetics, Nice University Hospital and CNRS UMR 6543, Faculty of Medicine, Nice, France.

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http://dx.doi.org/10.1002/pbc.21156DOI Listing
March 2008

Potential for treatment of liposarcomas with the MDM2 antagonist Nutlin-3A.

Int J Cancer 2007 Jul;121(1):199-205

Department of Tumour Biology, Rikshospitalet-Radiumhospitalet Medical Center, Oslo, Norway.

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http://dx.doi.org/10.1002/ijc.22643DOI Listing
July 2007

A clinical, histologic, and molecular study of 9 cases of congenital dermatofibrosarcoma protuberans.

Arch Dermatol 2007 Feb;143(2):203-10

Faculty of Medicine, Laboratory of Solid Tumors Genetics, Nice University Hospital, Nice, France.

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http://dx.doi.org/10.1001/archderm.143.2.203DOI Listing
February 2007

[From cytogenetics to cytogenomics of dermatofibrosarcoma protuberans family of tumors].

Bull Cancer 2007 Feb;94(2):179-89

Laboratoire de génétique des tumeurs solides, Centre hospitalier universitaire de Nice et CNRS UMR 6543, Faculté de Médecine, 28 avenue de Valombrose, 06107 Nice.

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February 2007

Diagnosis of primary esophageal synovial sarcoma by demonstration of t(X;18) translocation: a case report.

Virchows Arch 2006 Aug 21;449(2):262-7. Epub 2006 Jun 21.

Laboratory of Clinical and Experimental Pathology and Human Tissue Biobank Unit, 30 Avenue de la Voie Romaine, Louis Pasteur Hospital, 06002 Nice, France.

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http://dx.doi.org/10.1007/s00428-006-0234-1DOI Listing
August 2006

The spectrum of parathyroid gland dysfunction associated with the microdeletion 22q11.

Eur J Endocrinol 2006 Jul;155(1):47-52

Department of Endocrinology and Reproductive Medecine, Nice University Hospital, BP 3079, 06202 Nice cedex 3, France.

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http://dx.doi.org/10.1530/eje.1.02180DOI Listing
July 2006

Pseudosarcomatous myofibroblastic proliferations of the bladder: a clinicopathologic study of 42 cases.

Am J Surg Pathol 2006 Jul;30(7):787-94

Department of Pathology and Laboratory Medicine, Emory University Hospital, 1364 Clifton Road NE, Atlanta, GA 30322, USA.

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https://insights.ovid.com/crossref?an=00000478-200607000-000
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http://dx.doi.org/10.1097/01.pas.0000208903.46354.6fDOI Listing
July 2006

COL1A1-PDGFB fusion in a pediatric Bednar tumor with 2 copies of a der(22)t(17;22).

Cancer Genet Cytogenet 2006 Jul;168(2):155-7

Department of Pathology, Louisiana State University Health Science Center, New Orleans, LA, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S016546080600102
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http://dx.doi.org/10.1016/j.cancergencyto.2006.02.005DOI Listing
July 2006

Molecular cytogenetic characterization of a metastatic lung sarcomatoid carcinoma: 9p23 neocentromere and 9p23-p24 amplification including JAK2 and JMJD2C.

Cancer Genet Cytogenet 2006 Jun;167(2):122-30

Laboratory of Solid Tumors Genetics, Centre Hospitalier Universitaire de Nice and CNRS UMR 6543, Faculté de Medecine, 28 avenue de Valombrose, 06107 Nice, France.

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http://dx.doi.org/10.1016/j.cancergencyto.2006.01.004DOI Listing
June 2006

Chromosome size and origin as determinants of the level of CENP-A incorporation into human centromeres.

Chromosome Res 2004 ;12(8):805-15

The Murdoch Childrens Research Institute, Royal Children's Hospital, Flemington Road, Parkville 3052, Australia.

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http://link.springer.com/10.1007/s10577-005-5377-4
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http://dx.doi.org/10.1007/s10577-005-5377-4DOI Listing
May 2005

Molecular cytogenetic characterization of proximal-type epithelioid sarcoma.

Genes Chromosomes Cancer 2004 Nov;41(3):283-90

Unit of Molecular Cytogenetics, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano, Italy.

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http://dx.doi.org/10.1002/gcc.20086DOI Listing
November 2004

Monosomy 9q and trisomy 16q in a case of congenital solitary infantile myofibromatosis.

Virchows Arch 2004 Nov 9;445(5):537-40. Epub 2004 Sep 9.

Service de Pédiatrie, CHU de Nice, France.

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http://dx.doi.org/10.1007/s00428-004-1097-yDOI Listing
November 2004

[From cytogenetics to cytogenomics of adipose tissue tumors: 2. Malignant adipose tissue tumors].

Bull Cancer 2004 Apr;91(4):317-23

Laboratoire de génétique, Hôpital de l'Archet, CHU de Nice, 151, route de Saint-Antoine-de-Ginestière, BP 3079, 06202 Nice cedex 3.

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April 2004

11q13 alterations in two cases of hibernoma: large heterozygous deletions and rearrangement breakpoints near GARP in 11q13.5.

Genes Chromosomes Cancer 2003 Aug;37(4):389-95

Laboratoire de Génétique, Centre Hospitalier Universitaire de Nice, Université de Nice-Sophia Antipolis, France.

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http://doi.wiley.com/10.1002/gcc.10223
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http://dx.doi.org/10.1002/gcc.10223DOI Listing
August 2003

Genetics of dermatofibrosarcoma protuberans family of tumors: from ring chromosomes to tyrosine kinase inhibitor treatment.

Genes Chromosomes Cancer 2003 May;37(1):1-19

Service de Pédiatrie, Centre hospitalier universitaire de Nice, Nice, France.

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http://doi.wiley.com/10.1002/gcc.10202
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http://dx.doi.org/10.1002/gcc.10202DOI Listing
May 2003

[Inflammatory myofibroblastic tumors].

Ann Pathol 2002 Dec;22(6):453-60

Service de Pédiatrie, Hôpital de l'Archet, CHU de Nice, 06202 Nice Cedex 3.

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December 2002

[From cytogenetics to cytogenomics of adipose tissue tumors: 1. Benign adipose tissue tumors].

Bull Cancer 2002 Jul-Aug;89(7-8):689-95

Laboratoire de génétique, Hôpital de l'Archet, 151, route de Saint-Antoine-de-Ginestière, BP 3079, 06202 Nice Cedex 3, France.

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October 2002

Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor.

Genes Chromosomes Cancer 2002 Aug;34(4):354-62

Center for Human Genetics, Flanders Interuniversity Institute for Biotechnology (VIB), University of Leuven, Campus Gasthuisberg O&N 06, Herestraat 49, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1002/gcc.10033DOI Listing
August 2002

COL1A1-PDGFB gene fusion demonstrates a common histogenetic origin for dermatofibrosarcoma protuberans and its granular cell variant.

Am J Surg Pathol 2002 Jul;26(7):932-7

UF Recherche clinique 0952 and Laboratoire de Cytogénétique, Université de Bordeaux II and Institut Bergonié, France.

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http://dx.doi.org/10.1097/00000478-200207000-00013DOI Listing
July 2002