Publications by authors named "Florence Malisan"

23Publications

E3 Ligase RNF126 Directly Ubiquitinates Frataxin, Promoting Its Degradation: Identification of a Potential Therapeutic Target for Friedreich Ataxia.

Cell Rep 2017 02;18(8):2007-2017

Laboratory of Signal Transduction, Department of Biomedicine and Prevention, University of Rome "Tor Vergata," Via Montpellier 1, 00133 Rome, Italy; Fratagene Therapeutics Srl, Viale dei Campioni 8, 00144 Rome, Italy. Electronic address:

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February 2017

Src inhibitors modulate frataxin protein levels.

Hum Mol Genet 2015 Aug 6;24(15):4296-305. Epub 2015 May 6.

Laboratory of Signal Transduction, Department of Biomedicine and Prevention, University of Rome 'Tor Vergata', Via Montpellier 1, 00133 Rome, Italy,

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August 2015

Highly specific ubiquitin-competing molecules effectively promote frataxin accumulation and partially rescue the aconitase defect in Friedreich ataxia cells.

Neurobiol Dis 2015 Mar 27;75:91-9. Epub 2014 Dec 27.

Laboratory of Signal Transduction, Department of Biomedicine and Prevention, University of Rome "Tor Vergata," Via Montpellier 1, Rome 00133, Italy; Fratagene Therapeutics Ltd., 22 Northumberland Rd., Dublin, Ireland. Electronic address:

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March 2015

Recovery of immunological homeostasis positively correlates both with early stages of right-colorectal cancer and laparoscopic surgery.

PLoS One 2013 9;8(9):e74455. Epub 2013 Sep 9.

Surgical and Medical Department of the Clinical Sciences, Biomedical Technologies and Translational Medicine, Faculty of Medicine and Psychology University of Rome "Sapienza", Rome, Italy ; Sant'Andrea Hospital, Rome, Italy.

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June 2014

Preventing the ubiquitin-proteasome-dependent degradation of frataxin, the protein defective in Friedreich's ataxia.

Hum Mol Genet 2011 Apr 7;20(7):1253-61. Epub 2011 Jan 7.

Laboratory of Signal Transduction, Department of Experimental Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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April 2011

Molecular control of the cytosolic aconitase/IRP1 switch by extramitochondrial frataxin.

Hum Mol Genet 2010 Apr 6;19(7):1221-9. Epub 2010 Jan 6.

Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, Rome, Italy.

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April 2010

In vivo maturation of human frataxin.

Hum Mol Genet 2007 Jul 27;16(13):1534-40. Epub 2007 Apr 27.

Laboratory of Signal Transduction, Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, Rome, Italy.

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July 2007

A pool of extramitochondrial frataxin that promotes cell survival.

J Biol Chem 2006 Jun 11;281(24):16750-6. Epub 2006 Apr 11.

Laboratory of Signal Transduction, Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, via Montpellier 1, 00133 Rome, Italy.

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June 2006

9-O-acetyl GD3 protects tumor cells from apoptosis.

Int J Cancer 2006 Jul;119(1):67-73

Institute of Immunology, Technical University of Dresden, Dresden, Germany.

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July 2006

Ceramide catabolism critically controls survival of human dendritic cells.

J Leukoc Biol 2006 Jan 21;79(1):166-72. Epub 2005 Oct 21.

Department of Experimental Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.

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January 2006

The ganglioside GD3 as the Greek goddess Hecate: several faces turned towards as many directions.

IUBMB Life 2005 Jul;57(7):477-82

Laboratory of Immunology and Signal Transduction, Department of Experimental Medecine and Biochemical sciences, University "Tor Vergata", Rome, Italy.

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July 2005

Differential regulation of apoptotic cell death in senescent human cells.

Exp Gerontol 2004 Nov-Dec;39(11-12):1713-21

Department of Molecular and Cellular Biology, Institute for Biomedical Aging Research, Austrian Academy of Sciences, Rennweg 10, 6020 Innsbruck, Austria.

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April 2005

Calnexin suppresses GD3 synthase-induced apoptosis.

FASEB J 2004 Oct 19;18(13):1553-5. Epub 2004 Aug 19.

Laboratory of Immunology and Signal Transduction, Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, Rome, Italy.

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October 2004

Mitochondrial lipids as apoptosis regulators.

Curr Med Chem 2003 Aug;10(16):1573-80

Department of Experimental Medicine and Biochemical Sciences, University Tor Vergata, Via Montpellier, 1. 00133 Rome, Italy.

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August 2003