Publications by authors named "Florence Coulet"

71Publications

Utility of a mainstreamed genetic testing pathway in breast and ovarian cancer patients during the COVID-19 pandemic.

Eur J Med Genet 2020 Nov 10;63(12):104098. Epub 2020 Nov 10.

UF d'Oncogénétique, Département de Génétique et Institut Universitaire de Cancérologie, Groupe Hospitalier Pitié-Salpêtrière, AP-HP.Sorbonne Université, 47-83 Boulevard de l'Hôpital, F-75013 Paris, France; Sorbonne Université, INSERM, Unité Mixte de Recherche Scientifique 938 et SIRIC CURAMUS, Centre de Recherche Saint-Antoine, Equipe Instabilité des Microsatellites et Cancer, 184 rue du Faubourg Saint-Antoine, F-75012 Paris, France.

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http://dx.doi.org/10.1016/j.ejmg.2020.104098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654320PMC
November 2020

Parkes-Weber syndrome related to RASA1 mosaic mutation.

Clin Genet 2020 Oct 28. Epub 2020 Oct 28.

Department of Genetics, Hôpitaux Universitaires Pitié Salpêtrière-Charles Foix, APHP, Sorbonne Université, Paris, France.

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http://dx.doi.org/10.1111/cge.13860DOI Listing
October 2020

Molecular tumor testing in patients with Lynch-like syndrome reveals a de novo mosaic variant of a mismatch repair gene transmitted to offspring.

Eur J Hum Genet 2020 Nov 16;28(11):1624-1628. Epub 2020 Jul 16.

Department of Genetics, Hôpital Universitaire Pitié Salpêtrière (Assistance Publique-Hôpitaux de Paris), Paris VI University, Paris, France.

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http://dx.doi.org/10.1038/s41431-020-0689-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575584PMC
November 2020

Overcoming the challenges associated with universal screening for Lynch syndrome in colorectal and endometrial cancer.

Genet Med 2020 Aug 15;22(8):1422-1423. Epub 2020 May 15.

Laboratoire de Probabilités, Statistique et Modélisation, CNRS UMR 8001, Sorbonne Université, Paris, France.

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http://dx.doi.org/10.1038/s41436-020-0819-0DOI Listing
August 2020

Mechanisms and therapeutic implications of hypermutation in gliomas.

Nature 2020 04 15;580(7804):517-523. Epub 2020 Apr 15.

Department of Oncologic Pathology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41586-020-2209-9DOI Listing
April 2020

[Clinical Cancer Genetics: A guide for the pathologist].

Ann Pathol 2020 Apr 8;40(2):63-69. Epub 2020 Feb 8.

Département de génétique, DMU BioGeM, UF d'Oncogénétique, groupe hospitalier universitaire Pitié-Salpêtrière, AP-HP, Sorbonne université, 47-83, boulevard de l'Hôpital 75013 Paris, France; Faculté de médecine, Sorbonne université, 91, boulevard de l'Hôpital, 75013 Paris, France; INSERM, UMR_S 938, instabilité des microsatellites et cancer, centre de recherche Saint-Antoine, hôpital Saint-Antoine, 75012 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.annpat.2020.01.003DOI Listing
April 2020

Soft tissue angiomatosis: another PIK3CA-related disorder.

Histopathology 2020 Mar 24;76(4):540-549. Epub 2020 Jan 24.

Department of Pathology, Hôpital Universitaire Necker-Enfants Malades, APHP, Paris, France.

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http://dx.doi.org/10.1111/his.14021DOI Listing
March 2020

Germline Variants in Highly Selected Patients With Prostate Cancer.

JAMA Oncol 2019 Jul 11. Epub 2019 Jul 11.

Centre de Recherche Saint Antoine, INSERM UMR-S 938, Équipe Instabilité des Microsatellites et Cancers, Paris, France.

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http://dx.doi.org/10.1001/jamaoncol.2019.2106DOI Listing
July 2019

Methylation Tolerance-Based Functional Assay to Assess Variants of Unknown Significance in the MLH1 and MSH2 Genes and Identify Patients With Lynch Syndrome.

Gastroenterology 2019 08 15;157(2):421-431. Epub 2019 Apr 15.

Sorbonne Université, Inserm, Centre de Recherche Saint-Antoine, CRSA, Paris, France; Equipe labellisée par la Ligue Nationale contre le Cancer, Paris, France. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.03.071DOI Listing
August 2019

[Lynch syndrome: What is new?]

Bull Cancer 2019 Jul - Aug;106(7-8):647-655. Epub 2018 Dec 4.

AP-HP, Sorbonne université, hôpital Saint-Antoine, et service d'oncologie médicale, 184, rue du Faubourg Saint-Antoine, 75012 Paris, France; Sorbonne université, unité Mixte de Recherche Scientifique 938 et SIRIC CURAMUS, Centre de recherche Saint-Antoine, équipe instabilité des microsatellites et cancer, équipe labellisée par la Ligue Nationale contre le cancer, Inserm, 75012 Paris, France.

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http://dx.doi.org/10.1016/j.bulcan.2018.10.009DOI Listing
August 2019

Clinical implications of CTNNA1 germline mutations in asymptomatic carriers.

Gastric Cancer 2019 07 4;22(4):899-903. Epub 2018 Dec 4.

Laboratoire d'Oncogénétique, Unité fonctionnelle d'Oncogénétique, Département de Génétique, Groupe Hospitalier Pitié-Salpêtrière AP-HP, 75013, Paris, France.

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http://link.springer.com/10.1007/s10120-018-00907-7
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http://dx.doi.org/10.1007/s10120-018-00907-7DOI Listing
July 2019

Serous ovarian carcinoma in patients with Lynch syndrome: Caution is warranted.

Gynecol Oncol Rep 2018 Nov 12;26:69-70. Epub 2018 Oct 12.

Laboratoire d'Oncogénétique, Unité fonctionnelle d'Oncogénétique, Département de Génétique, Groupe Hospitalier Pitié-Salpêtrière AP-HP, F-75013 Paris, France.

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http://dx.doi.org/10.1016/j.gore.2018.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197616PMC
November 2018

BRCA1 and BRCA2 Germline Mutation Screening in Western Algeria using High Resolution Melting Analysis (HRM).

Gulf J Oncolog 2018 May;1(27):31-37

Lab. Bio.Dev.Diff.Université Oran1 Ahmed Ben Bella, Faculté des Sciences de la Nature et de la Vie, Département de Biologie, Oran, Algérie.

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May 2018

Clinical and genetic findings in children with central nervous system arteriovenous fistulas.

Ann Neurol 2017 Dec 12;82(6):972-980. Epub 2017 Dec 12.

Department of genetics, Hopital Pitié-Salpêtrière, Paris, France.

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http://dx.doi.org/10.1002/ana.25106DOI Listing
December 2017

Droplet digital PCR of circulating tumor cells from colorectal cancer patients can predict KRAS mutations before surgery.

Mol Oncol 2016 10 7;10(8):1221-31. Epub 2016 Jun 7.

Sorbonne Universités, UPMC Univ. Paris 06, F-75005, Paris, France; Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Department of Oncology and Endocrine Biochemistry, Paris, France; INSERM, UMR_S 1166, Institute of Cardiometabolism and Nutrition, ICAN, Paris, France.

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http://dx.doi.org/10.1016/j.molonc.2016.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423194PMC
October 2016

Genetic counselling in a national referral centre for pulmonary hypertension.

Eur Respir J 2016 Feb 23;47(2):541-52. Epub 2015 Dec 23.

Université Paris Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin Bicêtre, France AP-HP, Centre de Référence de l'Hypertension Pulmonaire Sévère, Département Hospitalo-Universitaire (DHU) Thorax Innovation (TORINO), Service de Pneumologie, Hôpital de Bicêtre, Le Kremlin Bicêtre, France UMR_S999, Université Paris-Sud, INSERM, Laboratoire d'Excellence (LabEx) en Recherche sur le Médicament et l'Innovation Thérapeutique (LERMIT), Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France

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http://erj.ersjournals.com/content/erj/early/2015/12/22/1399
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http://erj.ersjournals.com/lookup/doi/10.1183/13993003.00717
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http://dx.doi.org/10.1183/13993003.00717-2015DOI Listing
February 2016

Somatic c.34G>T KRAS mutation: a new prescreening test for MUTYH-associated polyposis?

Cancer Genet 2015 Jul-Aug;208(7-8):390-5. Epub 2015 Apr 23.

Department of Digestive Surgery, Hôpital Saint Antoine (Assistance Publique-Hôpitaux de Paris), Paris VI University, Paris, France.

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http://dx.doi.org/10.1016/j.cancergen.2015.04.005DOI Listing
October 2015

Characteristics of pulmonary arterial hypertension in affected carriers of a mutation located in the cytoplasmic tail of bone morphogenetic protein receptor type 2.

Chest 2015 May;147(5):1385-1394

University Paris-Sud, Le Kremlin-Bicêtre, France; Assistance Publique-Hôpitaux de Paris (AP-HP), Service de Pneumologie, Centre de Référence de l'Hypertension Pulmonaire Sévère, DHU Thorax Innovation, Hôpital Bicêtre, Le Kremlin-Bicêtre, France; Institut National de la Santé et de la Recherche Médicale (INSERM) U999, LabEx LERMIT, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00123692153836
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http://dx.doi.org/10.1378/chest.14-0880DOI Listing
May 2015

Genomic variations integrated database for MUTYH-associated adenomatous polyposis.

J Med Genet 2015 Jan 3;52(1):25-7. Epub 2014 Nov 3.

INSERM UMR_S910, Marseille, France Departments of medical Genetics and Gastroenterology, AP-HM La Timone, Marseille, France Gastroenterology Department, European Hospital, Marseille, France Oncology Department, Clairval Hospital, Marseille, France The first two authors contributed equally to this work.

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http://dx.doi.org/10.1136/jmedgenet-2014-102752DOI Listing
January 2015

The UMD-APC database, a model of nation-wide knowledge base: update with data from 3,581 variations.

Hum Mutat 2014 May 7;35(5):532-6. Epub 2014 Apr 7.

UMR_S910, INSERM, Marseille, France; AP-HM La Timone, Gastroenterology Department, Marseille, France.

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http://dx.doi.org/10.1002/humu.22539DOI Listing
May 2014

EIF2AK4 mutations cause pulmonary veno-occlusive disease, a recessive form of pulmonary hypertension.

Nat Genet 2014 Jan 1;46(1):65-9. Epub 2013 Dec 1.

1] Unité Mixte de Recherche en Santé (UMR_S 956), Université Pierre and Marie Curie Université Paris 06 (UPMC) and Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France. [2] Genetics Department, Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France. [3] Institute for Cardiometabolism and Nutrition (ICAN), Paris, France.

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http://dx.doi.org/10.1038/ng.2844DOI Listing
January 2014

Cleft lip, cleft palate, hereditary diffuse gastric cancer and germline mutations in CDH1.

Int J Cancer 2013 May 16;132(10):2470. Epub 2012 Nov 16.

Department of Medical Oncology, Institut Gustave Roussy, 94805 Villejuif, France.

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http://dx.doi.org/10.1002/ijc.27923DOI Listing
May 2013

Somatic mosaicism and double somatic hits can lead to MSI colorectal tumors.

Fam Cancer 2013 Mar;12(1):27-33

Department of Digestive Surgery, Hôpital Saint Antoine (AP-HP), Paris VI University, Paris, France.

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http://dx.doi.org/10.1007/s10689-012-9568-9DOI Listing
March 2013

Lynch or not Lynch? Is that always a question?

Adv Cancer Res 2012 ;113:121-66

INSERM, UMRS 938, Centre de Recherche Saint-Antoine, Equipe Instabilité des Microsatellites et Cancers, Paris, France.

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http://dx.doi.org/10.1016/B978-0-12-394280-7.00004-XDOI Listing
July 2012

Screening for Lynch syndrome in colorectal cancer: are we doing enough?

Ann Surg Oncol 2012 Mar 31;19(3):809-16. Epub 2011 Aug 31.

Department of Digestive Surgery, Hôpital Saint-Antoine, Université Pierre et Marie Curie, Paris, France.

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http://dx.doi.org/10.1245/s10434-011-2014-7DOI Listing
March 2012

A one-step prescreening for point mutations and large rearrangement in BRCA1 and BRCA2 genes using quantitative polymerase chain reaction and high-resolution melting curve analysis.

Genet Test Mol Biomarkers 2010 Oct 21;14(5):677-90. Epub 2010 Sep 21.

Laboratoire d'Oncogénétique et Angiogénétique moléculaire, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hopitaux de Paris, Université Pierre et Marie Curie, Paris, France.

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http://dx.doi.org/10.1089/gtmb.2009.0183DOI Listing
October 2010

MYH biallelic mutation can inactivate the two genetic pathways of colorectal cancer by APC or MLH1 transversions.

Fam Cancer 2010 Dec;9(4):589-94

Department of Digestive Surgery, Hôpital Saint-Antoine AP-HP, University Pierre et Marie Curie Paris VI, 184 rue du Faubourg Saint-Antoine, 75571 Paris, France.

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http://dx.doi.org/10.1007/s10689-010-9367-0DOI Listing
December 2010

KRAS mutation detection in Tunisian sporadic coloractal cancer patients with direct sequencing, high resolution melting and denaturating high performance liquid chromatography.

Cancer Biomark 2010-2011;8(6):331-40

Laboratoire de Génétique, Immunologie et Pathologies Humaines, Faculté des Sciences de Tunis, Université de Tunis El Manar, Tunisia.

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http://dx.doi.org/10.3233/CBM-2011-0222DOI Listing
March 2012

Prevalence of mutations in APC, CTNNB1, and BRAF in Tunisian patients with sporadic colorectal cancer.

Cancer Genet Cytogenet 2008 Nov;187(1):12-8

Laboratory of Human Genetics, Immunology, and Pathology, Faculty of Sciences-Tunis, University of Tunis, Campus Universitaire, El Manar I, Tunis 2092, Tunisia.

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http://dx.doi.org/10.1016/j.cancergencyto.2008.06.016DOI Listing
November 2008

First genetic analysis in Tunisian familial adenomatous polyposis probands.

Oncol Rep 2008 May;19(5):1213-8

Laboratoire de Génétique, Immunologie et Pathologies Humaines, Faculté des Sciences de Tunis, Tunis 2092, Tunisia.

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May 2008

Clinical outcomes of pulmonary arterial hypertension in carriers of BMPR2 mutation.

Am J Respir Crit Care Med 2008 Jun 20;177(12):1377-83. Epub 2008 Mar 20.

Université Paris-Sud 11, Service de Pneumologie et Réanimation Respiratoire, Hôpital Antoine-Béclère, 157 rue de la Porte de Trivaux, 92140 Clamart, France.

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http://dx.doi.org/10.1164/rccm.200712-1807OCDOI Listing
June 2008

Hereditary hemorrhagic telangiectasia: evidence for regional founder effects of ACVRL1 mutations in French and Italian patients.

Eur J Hum Genet 2008 Jun 20;16(6):742-9. Epub 2008 Feb 20.

Service de Génétique Moléculaire et Clinique, Hôpital Edouard Herriot, Université de Lyon, Université Lyon 1, 5 Place d'Arsonval, Lyon, France.

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http://dx.doi.org/10.1038/ejhg.2008.3DOI Listing
June 2008

Crosstalk between HIF-1 and ROCK pathways in neuronal differentiation of mesenchymal stem cells, neurospheres and in PC12 neurite outgrowth.

Mol Cell Neurosci 2007 Jul 10;35(3):409-23. Epub 2007 Apr 10.

UMR-CNRS 6185, Hypoxia and Cerebrovascular Physiopathology Group, University of Caen, CYCERON, Bd Henri Becquerel, BP 5229, F-14074 Caen cedex, France.

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http://dx.doi.org/10.1016/j.mcn.2007.04.002DOI Listing
July 2007

Genetic and acquired thrombotic factors in chronic hepatitis C.

Am J Gastroenterol 2004 Mar;99(3):527-31

Service d'Immunologie et Hématologie Biologiques, Hôpital Saint-Antoine Assistance Publique-Hôpitaux de Paris, Paris, France.

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http://dx.doi.org/10.1111/j.1572-0241.2004.04092.xDOI Listing
March 2004

Identification of hypoxia-response element in the human endothelial nitric-oxide synthase gene promoter.

J Biol Chem 2003 Nov 8;278(47):46230-40. Epub 2003 Sep 8.

INSERM, Unit 525, Université Pierre et Marie Curie, Faculté de Médecine Pitié-Salpêtrière, 91 Boulevard de l'Hôpital, 75013 Paris, France.

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http://dx.doi.org/10.1074/jbc.M305420200DOI Listing
November 2003