Publications by authors named "Flora Peyvandi"

100Publications

Increasing levels of von Willebrand Factor and factor VIII with age in patients affected by von Willebrand disease.

J Thromb Haemost 2020 Sep 30. Epub 2020 Sep 30.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, A. Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milan, Italy.

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http://dx.doi.org/10.1111/jth.15116DOI Listing
September 2020

Thrombin Generation in Preterm Newborns With Intestinal Failure-Associated Liver Disease.

Front Pediatr 2020 26;8:510. Epub 2020 Aug 26.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milan, Italy.

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http://dx.doi.org/10.3389/fped.2020.00510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479833PMC
August 2020

ISTH guidelines for the diagnosis of thrombotic thrombocytopenic purpura.

J Thromb Haemost 2020 Jul 17. Epub 2020 Jul 17.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milan, Italy.

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http://dx.doi.org/10.1111/jth.15006DOI Listing
July 2020

Good practice statements (GPS) for the clinical care of patients with thrombotic thrombocytopenic purpura.

J Thromb Haemost 2020 Aug 4. Epub 2020 Aug 4.

Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

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http://dx.doi.org/10.1111/jth.15009DOI Listing
August 2020

ISTH guidelines for treatment of thrombotic thrombocytopenic purpura.

J Thromb Haemost 2020 Jul 15. Epub 2020 Jul 15.

Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

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http://dx.doi.org/10.1111/jth.15010DOI Listing
July 2020

Emicizumab, the factor VIII mimetic bi-specific monoclonal antibody and its measurement in plasma.

Clin Chem Lab Med 2020 Sep 5. Epub 2020 Sep 5.

Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Università degli Studi di Milano, Milan, Italy.

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http://dx.doi.org/10.1515/cclm-2020-0696DOI Listing
September 2020

Hemostatic alterations in COVID-19.

Haematologica 2020 Aug 27. Epub 2020 Aug 27.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy;

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http://dx.doi.org/10.3324/haematol.2020.262634DOI Listing
August 2020

How I treat thrombotic thrombocytopenic purpura in pregnancy.

Blood 2020 Aug 13. Epub 2020 Aug 13.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milano, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.

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http://dx.doi.org/10.1182/blood.2019000962DOI Listing
August 2020

Romeo and Juliet: Revisited (at the time of COVID-19).

Eur J Intern Med 2020 Jul 7. Epub 2020 Jul 7.

Department of Clinical Sciences and Community Health, Milan, Italy; IRCCS Fondazione Ca' Granda, Ospedale Maggiore Policlinico, Università degli Studi di Milano, Via Francesco Sforza 28, 20122 Milan.

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http://dx.doi.org/10.1016/j.ejim.2020.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340036PMC
July 2020

Acute Portal Vein Thrombosis in SARS-CoV-2 Infection: A Case Report.

Am J Gastroenterol 2020 07;115(7):1140-1142

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, U.O.C. Medicina Generale Emostasi e Trombosi, University of Milan, Milan, Italy.

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http://dx.doi.org/10.14309/ajg.0000000000000711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273956PMC
July 2020

Dramatic presentation of acquired TTP associated with COVID-19.

Haematologica 2020 Jul 2. Epub 2020 Jul 2.

Dept of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy

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http://dx.doi.org/10.3324/haematol.2020.262345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556657PMC
July 2020

How I treat gastrointestinal bleeding in congenital and acquired von Willebrand disease.

Blood 2020 Sep;136(10):1125-1133

Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; and.

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http://dx.doi.org/10.1182/blood.2019003702DOI Listing
September 2020

Genomewide Association Study of Severe Covid-19 with Respiratory Failure.

Authors:
David Ellinghaus Frauke Degenhardt Luis Bujanda Maria Buti Agustín Albillos Pietro Invernizzi Javier Fernández Daniele Prati Guido Baselli Rosanna Asselta Marit M Grimsrud Chiara Milani Fátima Aziz Jan Kässens Sandra May Mareike Wendorff Lars Wienbrandt Florian Uellendahl-Werth Tenghao Zheng Xiaoli Yi Raúl de Pablo Adolfo G Chercoles Adriana Palom Alba-Estela Garcia-Fernandez Francisco Rodriguez-Frias Alberto Zanella Alessandra Bandera Alessandro Protti Alessio Aghemo Ana Lleo Andrea Biondi Andrea Caballero-Garralda Andrea Gori Anja Tanck Anna Carreras Nolla Anna Latiano Anna Ludovica Fracanzani Anna Peschuck Antonio Julià Antonio Pesenti Antonio Voza David Jiménez Beatriz Mateos Beatriz Nafria Jimenez Carmen Quereda Cinzia Paccapelo Christoph Gassner Claudio Angelini Cristina Cea Aurora Solier David Pestaña Eduardo Muñiz-Diaz Elena Sandoval Elvezia M Paraboschi Enrique Navas Félix García Sánchez Ferruccio Ceriotti Filippo Martinelli-Boneschi Flora Peyvandi Francesco Blasi Luis Téllez Albert Blanco-Grau Georg Hemmrich-Stanisak Giacomo Grasselli Giorgio Costantino Giulia Cardamone Giuseppe Foti Serena Aneli Hayato Kurihara Hesham ElAbd Ilaria My Iván Galván-Femenia Javier Martín Jeanette Erdmann Jose Ferrusquía-Acosta Koldo Garcia-Etxebarria Laura Izquierdo-Sanchez Laura R Bettini Lauro Sumoy Leonardo Terranova Leticia Moreira Luigi Santoro Luigia Scudeller Francisco Mesonero Luisa Roade Malte C Rühlemann Marco Schaefer Maria Carrabba Mar Riveiro-Barciela Maria E Figuera Basso Maria G Valsecchi María Hernandez-Tejero Marialbert Acosta-Herrera Mariella D'Angiò Marina Baldini Marina Cazzaniga Martin Schulzky Maurizio Cecconi Michael Wittig Michele Ciccarelli Miguel Rodríguez-Gandía Monica Bocciolone Monica Miozzo Nicola Montano Nicole Braun Nicoletta Sacchi Nilda Martínez Onur Özer Orazio Palmieri Paola Faverio Paoletta Preatoni Paolo Bonfanti Paolo Omodei Paolo Tentorio Pedro Castro Pedro M Rodrigues Aaron Blandino Ortiz Rafael de Cid Ricard Ferrer Roberta Gualtierotti Rosa Nieto Siegfried Goerg Salvatore Badalamenti Sara Marsal Giuseppe Matullo Serena Pelusi Simonas Juzenas Stefano Aliberti Valter Monzani Victor Moreno Tanja Wesse Tobias L Lenz Tomas Pumarola Valeria Rimoldi Silvano Bosari Wolfgang Albrecht Wolfgang Peter Manuel Romero-Gómez Mauro D'Amato Stefano Duga Jesus M Banales Johannes R Hov Trine Folseraas Luca Valenti Andre Franke Tom H Karlsen

N Engl J Med 2020 10 17;383(16):1522-1534. Epub 2020 Jun 17.

From the Institute of Clinical Molecular Biology, Christian-Albrechts-University (D.E., F.D., J.K., S. May, M. Wendorff, L.W., F.U.-W., X.Y., A.T., A. Peschuck, C.G., G.H.-S., H.E.A., M.C.R., M.E.F.B., M. Schulzky, M. Wittig, N.B., S.J., T.W., W.A., M. D'Amato, A.F.), and University Hospital Schleswig-Holstein, Campus Kiel (N.B., A.F.), Kiel, the Institute for Cardiogenetics, University of Lübeck, Lübeck (J.E.), the German Research Center for Cardiovascular Research, partner site Hamburg-Lübeck-Kiel (J.E.), the University Heart Center Lübeck (J.E.), and the Institute of Transfusion Medicine, University Hospital Schleswig-Holstein (S.G.), Lübeck, Stefan-Morsch-Stiftung, Birkenfeld (M. Schaefer, W.P.), and the Research Group for Evolutionary Immunogenomics, Max Planck Institute for Evolutionary Biology, Plön (O.O., T.L.L.) - all in Germany; Novo Nordisk Foundation Center for Protein Research, Disease Systems Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen (D.E.); the Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute-Donostia University Hospital-University of the Basque Country (L.B., K.G.-E., L.I.-S., P.M.R., J.M.B.), Osakidetza Basque Health Service, Donostialdea Integrated Health Organization, Clinical Biochemistry Department (A.G.C., B.N.J.), and the Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute (M. D'Amato), San Sebastian, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas, Instituto de Salud Carlos III (L.B., M. Buti, A. Albillos, A. Palom, F.R.-F., B.M., L. Téllez, K.G.-E., L.I.-S., F.M., L.R., M.R.-B., M. Rodríguez-Gandía, P.M.R., M. Romero-Gómez, J.M.B.), the Departments of Gastroenterology (A. Albillos, B.M., L. Téllez, F.M., M. Rodríguez-Gandía), Intensive Care (R.P., A.B.O.), Respiratory Diseases (D.J., A.S., R.N.), Infectious Diseases (C.Q., E.N.), and Anesthesiology (D. Pestaña, N. Martínez), Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria, University of Alcalá, and Histocompatibilidad y Biologia Molecular, Centro de Transfusion de Madrid (F.G.S.), Madrid, the Liver Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus (M. Buti, A. Palom, L.R., M.R.-B.), Hospital Clinic, University of Barcelona, and the August Pi i Sunyer Biomedical Research Institute (J.F., F.A., E.S., J.F.-A., L.M., M.H.-T., P.C.), the European Foundation for the Study of Chronic Liver Failure (J.F.), Vall d'Hebron Institut de Recerca (A. Palom, F.R.-F., A.J., S. Marsal), and the Departments of Biochemistry (A.-E.G.-F., F.R.-F., A.C.-G., C.C., A.B.-G.), Intensive Care (R.F.), and Microbiology (T.P.), University Hospital Vall d'Hebron, the Immunohematology Department, Banc de Sang i Teixits, Autonomous University of Barcelona (E.M.-D.), Catalan Institute of Oncology, Bellvitge Biomedical Research Institute, Consortium for Biomedical Research in Epidemiology and Public Health and University of Barcelona, l'Hospitalet (V. Moreno), and Autonoma University of Barcelona (T.P.), Barcelona, Universitat Autònoma de Barcelona, Bellatera (M. Buti, F.R.-F., M.R.-B.), GenomesForLife-GCAT Lab Group, Germans Trias i Pujol Research Institute (A.C.N., I.G.-F., R.C.), and High Content Genomics and Bioinformatics Unit, Germans Trias i Pujol Research Institute (L. Sumoy), Badalona, Institute of Parasitology and Biomedicine Lopez-Neyra, Granada (J.M., M.A.-H.), the Digestive Diseases Unit, Virgen del Rocio University Hospital, Institute of Biomedicine of Seville, University of Seville, Seville (M. Romero-Gómez), and Ikerbasque, Basque Foundation for Science, Bilbao (M. D'Amato, J.M.B.) - all in Spain; the Division of Gastroenterology, Center for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milan Bicocca (P.I., C.M.), Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (D. Prati, G.B., A.Z., A. Bandera, A.G., A.L.F., A. Pesenti, C.P., F.C., F.M.-B., F.P., F.B., G.G., G. Costantino, L. Terranova, L. Santoro, L. Scudeller, M. Carrabba, M. Baldini, M.M., N. Montano, R.G., S.P., S. Aliberti, V. Monzani, S. Bosari, L.V.), the Department of Biomedical Sciences, Humanitas University (R.A., A. Protti, A. Aghemo, A. Lleo, E.M.P., G. Cardamone, M. Cecconi, V.R., S.D.), Humanitas Clinical and Research Center, IRCCS (R.A., A. Protti, A. Aghemo, A. Lleo, A.V., C.A., E.M.P., H.K., I.M., M. Cecconi, M. Ciccarelli, M. Bocciolone, P.P., P.O., P.T., S. Badalamenti, S.D.), University of Milan (A.Z., A. Bandera, A.G., A.L.F., A. Pesenti, F.M.-B., F.P., F.B., G.G., G. Costantino, M.M., N. Montano, R.G., S.P., S. Aliberti, S. Bosari, L.V.), and the Center of Bioinformatics, Biostatistics, and Bioimaging (M.G.V.) and the Phase 1 Research Center (M. Cazzaniga), School of Medicine and Surgery, and the Departments of Emergency, Anesthesia, and Intensive Care (G.F.), Pneumologia (P.F.), and Infectious Diseases (P.B.); University of Milano-Bicocca, Milan, the European Reference Network on Hepatological Diseases (P.I., C.M.) and the Infectious Diseases Unit (P.B.), San Gerardo Hospital, Monza, the Pediatric Departement and Centro Tettamanti-European Reference Network PaedCan, EuroBloodNet, MetabERN-University of Milano-Bicocca-Fondazione MBBM-Ospedale, San Gerardo (A. Biondi, L.R.B., M. D'Angiò), the Gastroenterology Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (A. Latiano, O.P.), the Department of Medical Sciences, Università degli Studi di Torino, Turin (S. Aneli, G.M.), and the Italian Bone Marrow Donor Registry, E.O. Ospedali Galliera, Genoa (N.S.) - all in Italy; the Norwegian PSC Research Center, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases, and Transplantation, and the Research Institute for Internal Medicine, Division of Surgery, Inflammatory Diseases, and Transplantation, Oslo University Hospital Rikshospitalet and University of Oslo (M.M.G., J.R.H., T.F., T.H.K.), and the Section for Gastroenterology, Department of Transplantation Medicine, Division for Cancer Medicine, Surgery, and Transplantation, Oslo University Hospital Rikshospitalet (J.R.H., T.F., T.H.K.), Oslo; the School of Biological Sciences, Monash University, Clayton, VIC, Australia (T.Z., M. D'Amato); Private University in the Principality of Liechtenstein (C.G.); the Institute of Biotechnology, Vilnius University, Vilnius, Lithuania (S.J.); and the Unit of Clinical Epidemiology, Department of Medicine Solna, Karolinska Institutet, Stockholm (M. D'Amato).

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http://dx.doi.org/10.1056/NEJMoa2020283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315890PMC
October 2020

Hemophilia gene therapy knowledge and perceptions: Results of an international survey.

Res Pract Thromb Haemost 2020 May 19;4(4):644-651. Epub 2020 Mar 19.

Katholieke Universiteit Leuven Vrije University Brussels Brussels Belgium.

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http://dx.doi.org/10.1002/rth2.12326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292673PMC
May 2020

Complement activation in patients with COVID-19: A novel therapeutic target.

J Allergy Clin Immunol 2020 Jul 14;146(1):215-217. Epub 2020 May 14.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.

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http://dx.doi.org/10.1016/j.jaci.2020.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224678PMC
July 2020

Pulmonary embolism in a young pregnant woman with COVID-19.

Thromb Res 2020 07 20;191:36-37. Epub 2020 Apr 20.

Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, A. Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy; Department of Pathophysiology and Transplantation for Health, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1016/j.thromres.2020.04.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169886PMC
July 2020

Where do we stand with antithrombotic prophylaxis in patients with COVID-19?

Thromb Res 2020 07 20;191:29. Epub 2020 Apr 20.

Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, A. Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2020.04.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169902PMC
July 2020

Is placental blood a reliable source for the evaluation of neonatal hemostasis at birth?

Transfusion 2020 05 21;60(5):1069-1077. Epub 2020 Apr 21.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, NICU, Milan, Italy.

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http://dx.doi.org/10.1111/trf.15785DOI Listing
May 2020

Hypercoagulability of COVID-19 patients in intensive care unit: A report of thromboelastography findings and other parameters of hemostasis.

J Thromb Haemost 2020 07 24;18(7):1738-1742. Epub 2020 Jun 24.

Fondazione IRCCS Ca' Granda Ospedale Maggiore, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milano, Italy.

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http://dx.doi.org/10.1111/jth.14850DOI Listing
July 2020

Effect of different methods for outlier detection and rejection when calculating cut off values for diagnosis of lupus anticoagulants.

Thromb Res 2020 06 26;190:20-25. Epub 2020 Mar 26.

Foundation IRCCS Ca' Granda Maggiore Policlinico Hospital, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2020.03.018DOI Listing
June 2020

A fatal case of COVID-19 pneumonia occurring in a patient with severe acute ulcerative colitis.

Gut 2020 06 3;69(6):1148-1149. Epub 2020 Apr 3.

Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy

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http://dx.doi.org/10.1136/gutjnl-2020-321183DOI Listing
June 2020

Prevalence of the age-related diseases in older patients with acquired thrombotic thrombocytopenic purpura.

Eur J Intern Med 2020 May 20;75:79-83. Epub 2020 Mar 20.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano,Via Pace 9, Milan, 20122, Italy; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, and Fondazione Luigi Villa, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejim.2020.01.024DOI Listing
May 2020

Laboratory testing in hemophilia: Impact of factor and non-factor replacement therapy on coagulation assays.

J Thromb Haemost 2020 06 23;18(6):1242-1255. Epub 2020 Apr 23.

Hämostaseologie, Campus Innenstadt, Klinikum der Universität München, München, Germany.

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http://dx.doi.org/10.1111/jth.14784DOI Listing
June 2020

Risk of pregnancy-related venous thromboembolism and obstetrical complications in women with inherited type I antithrombin deficiency: a retrospective, single-centre, cohort study.

Lancet Haematol 2020 Apr 26;7(4):e320-e328. Epub 2020 Feb 26.

Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca' Granda-Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/S2352-3026(20)30007-7DOI Listing
April 2020

Evaluation of a fully automated von Willebrand factor assay panel for the diagnosis of von Willebrand disease.

Haemophilia 2020 Mar 27;26(2):298-305. Epub 2020 Feb 27.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione Luigi Villa, Milan, Italy.

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http://dx.doi.org/10.1111/hae.13929DOI Listing
March 2020

Responsiveness of the activated partial thromboplastin time and dilute thrombin time to argatroban: Results of an in vitro study.

Int J Lab Hematol 2020 06 21;42(3):e128-e131. Epub 2020 Feb 21.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milano, Italy.

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http://dx.doi.org/10.1111/ijlh.13165DOI Listing
June 2020

An international registry of patients with plasminogen deficiency (HISTORY).

Haematologica 2020 Mar 30;105(3):554-561. Epub 2020 Jan 30.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milan, Italy.

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http://dx.doi.org/10.3324/haematol.2019.241158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049368PMC
March 2020

Perceived well-being and mental health in haemophilia.

Psychol Health Med 2020 Jan 26:1-11. Epub 2020 Jan 26.

Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Università degli Studi di Milano, Milano, Italy.

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http://dx.doi.org/10.1080/13548506.2020.1717556DOI Listing
January 2020

Novel variant in HPS3 gene in a patient with Hermansky Pudlak syndrome (HPS) type 3.

Platelets 2020 Oct 27;31(7):960-963. Epub 2019 Dec 27.

Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Faculty of Medicine, Medical Center - University of Freiburg , Germany.

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http://dx.doi.org/10.1080/09537104.2019.1704716DOI Listing
October 2020

Adult-Onset Still Disease After Human Herpesvirus 6 Infection in an Elderly Patient: A Case Report.

J Clin Rheumatol 2019 Nov 21. Epub 2019 Nov 21.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, UOC Medicina Generale-Emostasi e Trombosi, Milan, Italy First Infectious Department, AO FBF Luigi Sacco, Milan, Italy Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milan, Italy Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy

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http://dx.doi.org/10.1097/RHU.0000000000001225DOI Listing
November 2019

Management of rare acquired bleeding disorders.

Hematology Am Soc Hematol Educ Program 2019 12;2019(1):80-87

Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy; and.

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http://dx.doi.org/10.1182/hematology.2019000066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913473PMC
December 2019

Procoagulant imbalance in preterm neonates detected by thrombin generation procedures.

Thromb Res 2020 01 15;185:96-101. Epub 2019 Nov 15.

NICU, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.

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http://dx.doi.org/10.1016/j.thromres.2019.11.013DOI Listing
January 2020

Atypical primary cutaneous cryptococcosis during ibrutinib therapy for chronic lymphocytic leukemia.

Ann Hematol 2019 Dec 18;98(12):2847-2849. Epub 2019 Nov 18.

UOC Medicina Generale - Emostasi e Trombosi, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

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http://dx.doi.org/10.1007/s00277-019-03837-1DOI Listing
December 2019

Effect of emicizumab on global coagulation assays for plasma supplemented with apixaban or argatroban.

J Thromb Thrombolysis 2020 Apr;49(3):413-419

Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Via Pace 9, 20122, Milan, Italy.

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http://dx.doi.org/10.1007/s11239-019-01993-9DOI Listing
April 2020

The features of acquired thrombotic thrombocytopenic purpura occurring at advanced age.

Thromb Res 2020 03 22;187:197-201. Epub 2019 Oct 22.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione Luigi Villa, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2019.10.010DOI Listing
March 2020

Evaluation of a New, Rapid, Fully Automated Assay for the Measurement of ADAMTS13 Activity.

Thromb Haemost 2019 Nov 6;119(11):1767-1772. Epub 2019 Oct 6.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milano, A. Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milan, Italy.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1696718
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http://dx.doi.org/10.1055/s-0039-1696718DOI Listing
November 2019

Long-term neuropsychological sequelae, emotional wellbeing and quality of life in patients with acquired thrombotic thrombocytopenic purpura.

Haematologica 2020 Jul 26;105(7):1957-1962. Epub 2019 Sep 26.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.

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http://dx.doi.org/10.3324/haematol.2019.226423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327631PMC
July 2020

Patterns of infections in older patients acutely admitted to medical wards: data from the REPOSI register.

Intern Emerg Med 2019 11 23;14(8):1347-1352. Epub 2019 Aug 23.

Department of Pathophysiology and Transplantation, Università Degli Studi Di Milano, Milan, Italy.

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http://dx.doi.org/10.1007/s11739-019-02178-1DOI Listing
November 2019

Procoagulant imbalance influences cardiovascular and liver damage in chronic hepatitis C independently of steatosis.

Liver Int 2019 12 30;39(12):2309-2316. Epub 2019 Aug 30.

Unit of Medicine and Metabolic Diseases, Pathophysiology and Transplantation Department, Fondazione Ca' Granda IRCCS Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1111/liv.14213DOI Listing
December 2019

Real-life experience in switching to new extended half-life products at European haemophilia centres.

Haemophilia 2019 Nov 16;25(6):946-952. Epub 2019 Aug 16.

Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK.

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http://dx.doi.org/10.1111/hae.13834DOI Listing
November 2019

Phase 3 study of recombinant von Willebrand factor in patients with severe von Willebrand disease who are undergoing elective surgery: Reply.

Authors:
Flora Peyvandi

J Thromb Haemost 2019 08;17(8):1405-1406

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.

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http://dx.doi.org/10.1111/jth.14545DOI Listing
August 2019

How we make an accurate diagnosis of von Willebrand disease.

Thromb Res 2019 Jul 16. Epub 2019 Jul 16.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milan, Italy; Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy.

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http://dx.doi.org/10.1016/j.thromres.2019.07.010DOI Listing
July 2019

Burden of mild haemophilia A: Systematic literature review.

Haemophilia 2019 Sep 11;25(5):755-763. Epub 2019 Jul 11.

BioMarin Pharmaceutical Inc., Novato, California.

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http://dx.doi.org/10.1111/hae.13777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852304PMC
September 2019

Clinical advances in gene therapy updates on clinical trials of gene therapy in haemophilia.

Haemophilia 2019 Sep 8;25(5):738-746. Epub 2019 Jul 8.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milan, Italy.

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http://dx.doi.org/10.1111/hae.13816DOI Listing
September 2019

Molecular Aggregation of Marketed Recombinant FVIII Products: Biochemical Evidence and Functional Effects.

TH Open 2019 Apr 8;3(2):e123-e131. Epub 2019 May 8.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Luigi Villa Foundation, Milan, Italy.

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http://dx.doi.org/10.1055/s-0039-1688413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524925PMC
April 2019

Evolution of replacement therapy for von Willebrand disease: From plasma fraction to recombinant von Willebrand factor.

Blood Rev 2019 11 3;38:100572. Epub 2019 Apr 3.

Centre for Thrombosis and Hemostasis, Lund University, Malmö, Sweden.

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http://dx.doi.org/10.1016/j.blre.2019.04.001DOI Listing
November 2019

Evaluation of an automated chromogenic assay for Factor VIII clotting activity measurement in patients affected by haemophilia A.

Haemophilia 2019 May 2;25(3):521-526. Epub 2019 May 2.

Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

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http://dx.doi.org/10.1111/hae.13746DOI Listing
May 2019

Rescue factor VIII replacement to secure hemostasis in a patient with hemophilia A and inhibitors on emicizumab prophylaxis undergoing hip replacement.

Haematologica 2019 08 28;104(8):e380-e382. Epub 2019 Mar 28.

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and.

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http://dx.doi.org/10.3324/haematol.2018.215129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669151PMC
August 2019

Clinical and Laboratory Features of Patients with Acquired Thrombotic Thrombocytopenic Purpura: Fourteen Years of the Milan TTP Registry.

Thromb Haemost 2019 May 12;119(5):695-704. Epub 2019 Mar 12.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione Luigi Villa, Milan, Italy.

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http://dx.doi.org/10.1055/s-0039-1679907DOI Listing
May 2019

Complications of whole-exome sequencing for causal gene discovery in primary platelet secretion defects.

Haematologica 2019 10 28;104(10):2084-2090. Epub 2019 Feb 28.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan

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http://dx.doi.org/10.3324/haematol.2018.204990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886420PMC
October 2019

Understanding the Impact of Aberrant Splicing in Coagulation Factor V Deficiency.

Int J Mol Sci 2019 Feb 20;20(4). Epub 2019 Feb 20.

Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20090 Milan, Italy.

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http://dx.doi.org/10.3390/ijms20040910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412230PMC
February 2019

Risk of diagnostic delay in congenital thrombotic thrombocytopenic purpura.

J Thromb Haemost 2019 Apr 6;17(4):666-669. Epub 2019 Mar 6.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milan, Italy.

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http://dx.doi.org/10.1111/jth.14409DOI Listing
April 2019

Body mass index reduction improves the baseline procoagulant imbalance of obese subjects.

J Thromb Thrombolysis 2019 Jul;48(1):52-60

IRCCS Cà Granda Maggiore Hospital Foundation, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi villa, Via Pace 9, 20122, Milano, Italy.

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http://dx.doi.org/10.1007/s11239-019-01818-9DOI Listing
July 2019

Prevention of relapse in patients with acquired thrombotic thrombocytopenic purpura undergoing elective surgery: a case series.

J Thromb Haemost 2019 03 25;17(3):492-498. Epub 2019 Feb 25.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.

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http://doi.wiley.com/10.1111/jth.14381
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http://dx.doi.org/10.1111/jth.14381DOI Listing
March 2019

Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura.

N Engl J Med 2019 01 9;380(4):335-346. Epub 2019 Jan 9.

From the Department of Haematology, University College London Hospitals, Cardiometabolic Program, National Institute for Health Research UCLH-UCL Biomedical Research Center, London (M.S.); the Division of Hematology, Department of Internal Medicine, Ohio State University, Columbus (S.R.C.); Fondazione Istituti di Ricovero e Cura a Carattere Scientifico Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, and the Department of Pathophysiology and Transplantation, University of Milan, Milan (F.P.); the Department of Hematology, Saint-Antoine University Hospital, Paris (P.C.); the Department of Medicine 1, Division of Hematology and Hemostasis, Medical University of Vienna, Vienna (P.K.); the Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland (J.A.K.H.); the Division of Hematology, Duke University School of Medicine, Durham, NC (A.M.); the Hematology Department, Universidad Católica de Valencia Hospital Dr. Peset, Valencia, Spain (J.R.); the Departments of Medicine and Laboratory Medicine, St. Michael's Hospital and University of Toronto, Toronto (K.P.); and Clinical Development, Ablynx, Zwijnaarde, Belgium (F.C., D.B., H.D.W., R.K.Z.).

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http://dx.doi.org/10.1056/NEJMoa1806311DOI Listing
January 2019

Thrombin generation assay for testing hemostatic effect of factor VIII concentrates in patients with hemophilia A and inhibitors: In vitro results from the PredicTGA study.

Thromb Res 2019 02 6;174:84-87. Epub 2018 Dec 6.

IRCCS Cà Granda Maggiore Policlinico Hospital Foundation, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milano, Italy.

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http://dx.doi.org/10.1016/j.thromres.2018.12.007DOI Listing
February 2019

Treatment of rare factor deficiencies other than hemophilia.

Blood 2019 01 17;133(5):415-424. Epub 2018 Dec 17.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and.

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http://dx.doi.org/10.1182/blood-2018-06-820738DOI Listing
January 2019

Thromboelastometry. Reproducibility of duplicate measurement performed by the RoTem® device.

Thromb Res 2018 12 31;172:139-141. Epub 2018 Oct 31.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milan, Italy.

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http://dx.doi.org/10.1016/j.thromres.2018.10.030DOI Listing
December 2018

Severe acquired von Willebrand syndrome secondary to systemic lupus erythematosus.

Haemophilia 2019 01 8;25(1):e30-e32. Epub 2018 Nov 8.

Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

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http://doi.wiley.com/10.1111/hae.13626
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http://dx.doi.org/10.1111/hae.13626DOI Listing
January 2019

Advances in the Treatment of Hemophilia: Implications for Laboratory Testing.

Clin Chem 2019 02 3;65(2):254-262. Epub 2018 Oct 3.

Angelo Bianchi Bonomi Hemophilia and Thrombosis Center.

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http://www.clinchem.org/lookup/doi/10.1373/clinchem.2017.284
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http://dx.doi.org/10.1373/clinchem.2017.284356DOI Listing
February 2019

Product type and other environmental risk factors for inhibitor development in severe hemophilia A.

Res Pract Thromb Haemost 2018 Apr 10;2(2):220-227. Epub 2018 Apr 10.

Angelo Bianchi Bonomi Hemophilia and Thrombosis Center Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Fondazione Luigi Villa Milan Italy.

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http://dx.doi.org/10.1002/rth2.12094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055565PMC
April 2018

Next-generation DNA sequencing to identify novel genetic risk factors for cerebral vein thrombosis.

Thromb Res 2018 09 15;169:76-81. Epub 2018 Jun 15.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy; Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico and Fondazione Luigi Villa, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2018.06.011DOI Listing
September 2018

Evaluation of the Utility of von Willebrand Factor Propeptide in the Differential Diagnosis of von Willebrand Disease and Acquired von Willebrand Syndrome.

Semin Thromb Hemost 2019 Feb 18;45(1):36-42. Epub 2018 Jun 18.

Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico and Luigi Villa Foundation, Milan, Italy.

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http://dx.doi.org/10.1055/s-0038-1660481DOI Listing
February 2019

Risk factors for inhibitor development in severe hemophilia a.

Thromb Res 2018 08 25;168:20-27. Epub 2018 May 25.

Angelo Bianchi Bonomi Hemophilia and Thrombosis Centre, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico and Luigi Villa Foundation, Milan, Italy; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2018.05.027DOI Listing
August 2018

Use of oral anticoagulant drugs in older patients with atrial fibrillation in internal medicine wards.

Eur J Intern Med 2018 06 12;52:e12-e14. Epub 2018 Apr 12.

Azienda Ospedaliero-Universitaria "Policlinico-Vittorio Emanuele" di Catania - Medicina Interna, Italy.

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http://dx.doi.org/10.1016/j.ejim.2018.04.006DOI Listing
June 2018

An unusual diagnosis in a 31-year-old man with abdominal pain and hyponatremia.

Intern Emerg Med 2018 Dec 17;13(8):1233-1238. Epub 2018 Mar 17.

Medicina Interna, Dipartimento di Scienze Cliniche e Comunità, Università degli Studi di Milano, Ospedale Maggiore Policlinico, Fondazione IRCCS Ca' Granda, Milan, Italy.

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http://link.springer.com/10.1007/s11739-018-1826-x
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http://dx.doi.org/10.1007/s11739-018-1826-xDOI Listing
December 2018

Recurrent thrombosis in patients with antiphospholipid antibodies treated with vitamin K antagonists or rivaroxaban.

Haematologica 2018 07 8;103(7):e315-e317. Epub 2018 Mar 8.

A. Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milano, Italy.

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http://dx.doi.org/10.3324/haematol.2017.185132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029544PMC
July 2018

Further comments on "High-titre inhibitors in previously untreated patients with severe haemophilia A receiving recombinant or plasma-derived factor VIII: a budget-impact analysis".

Blood Transfus 2019 01 22;17(1):86. Epub 2017 Dec 22.

"A. Bianchi Bonomi" Haemophilia and Thrombosis Centre, "Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico" and Luigi Villa" Foundation, Milan, Italy.

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http://www.bloodtransfusion.it/articolosing.aspx?id=000950
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http://dx.doi.org/10.2450/2017.0253-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343594PMC
January 2019

Idelalisib rapidly improves platelet function tests in patients with chronic lymphocytic leukaemia.

Br J Haematol 2018 12 7;183(5):825-828. Epub 2018 Jan 7.

Haematology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico of Milan, Milan, Italy.

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http://dx.doi.org/10.1111/bjh.15052DOI Listing
December 2018

Efficacy and safety of a new human fibrinogen concentrate in patients with congenital fibrinogen deficiency: an interim analysis of a Phase III trial.

Transfusion 2018 02 30;58(2):413-422. Epub 2017 Nov 30.

Angelo Bianchi Bonomi Hemophilia and Thrombosis Centre, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico and Luigi Villa Foundation, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.

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http://doi.wiley.com/10.1111/trf.14421
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http://dx.doi.org/10.1111/trf.14421DOI Listing
February 2018

Platelet to Lymphocyte Ratio and Neutrophil to Lymphocyte Ratio as Risk Factors for Venous Thrombosis.

Clin Appl Thromb Hemost 2018 Jul 31;24(5):808-814. Epub 2017 Oct 31.

1 Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, Milan, Italy.

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http://dx.doi.org/10.1177/1076029617733039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714878PMC
July 2018