Flavio Caprioli

Flavio Caprioli

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Flavio Caprioli

Publications by authors named "Flavio Caprioli"

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The role of interleukin-13 in chronic inflammatory intestinal disorders.

Autoimmun Rev 2019 May 4;18(5):549-555. Epub 2019 Mar 4.

First Department of Internal Medicine, University of Pavia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15689972193006
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http://dx.doi.org/10.1016/j.autrev.2019.03.012DOI Listing
May 2019

Use of biosimilars in inflammatory bowel disease: a position update of the Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD).

Dig Liver Dis 2019 May 19;51(5):632-639. Epub 2019 Feb 19.

IBD Unit, Presidio Columbus, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Università Cattolica del Sacro Cuore, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2019.02.004DOI Listing
May 2019

Outcome in ulcerative colitis after switch from adalimumab/golimumab to infliximab: A multicenter retrospective study.

Dig Liver Dis 2019 04 28;51(4):510-515. Epub 2018 Oct 28.

Clinical Unit for Chronic Bowel Disorders, Dept. of Clinical and Experimental Medicine, University of Messina, Messina, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2018.10.013DOI Listing
April 2019

Previous colonic resection is a risk factor for surgical relapse in Crohn's disease.

Dig Liver Dis 2019 02 4;51(2):206-211. Epub 2018 Aug 4.

Department of Pathophysiology and Transplantation, University of Milan, Italy; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda, Ospedale Policlinico, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2018.07.035DOI Listing
February 2019

Using Robotic Systems to Process and Embed Colonic Murine Samples for Histological Analyses.

J Vis Exp 2019 Jan 7(143). Epub 2019 Jan 7.

Department of Experimental Oncology, European Institute of Oncology;

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http://dx.doi.org/10.3791/58654DOI Listing
January 2019

CD4 T Helper Cell Plasticity in Infection, Inflammation, and Autoimmunity.

Mediators Inflamm 2017 29;2017:7083153. Epub 2017 Jan 29.

Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

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http://dx.doi.org/10.1155/2017/7083153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303579PMC
September 2018

Non-invasive evaluation of intestinal disorders: The role of elastographic techniques.

World J Gastroenterol 2017 Apr;23(16):2832-2840

Federica Branchi, Flavio Caprioli, Stefania Orlando, Dario Conte, Mirella Fraquelli, Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

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http://dx.doi.org/10.3748/wjg.v23.i16.2832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413779PMC
April 2017

Predicting Outcomes to Optimize Disease Management in Inflammatory Bowel Diseases.

J Crohns Colitis 2016 Dec 9;10(12):1385-1394. Epub 2016 Jun 9.

The Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY, USA

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http://dx.doi.org/10.1093/ecco-jcc/jjw116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174730PMC
December 2016

Challenges in treating patients with inflammatory bowel disease and concurrent viral hepatitis infection.

Expert Rev Gastroenterol Hepatol 2016 Dec 20;10(12):1373-1383. Epub 2016 Oct 20.

a A.M. and A. Migliavacca Center for Liver Disease, Division of Gastroenterology and Hepatology , Fondazione IRCCS CA' Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano , Milan , Italy.

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http://dx.doi.org/10.1080/17474124.2016.1246181DOI Listing
December 2016

Evolving roles of cross-sectional imaging in Crohn's disease.

Dig Liver Dis 2016 Sep 30;48(9):975-83. Epub 2016 May 30.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Italy; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda, Ospedale Policlinico di Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2016.05.017DOI Listing
September 2016

PNPLA3 148M Carriers with Inflammatory Bowel Diseases Have Higher Susceptibility to Hepatic Steatosis and Higher Liver Enzymes.

Inflamm Bowel Dis 2016 Jan;22(1):134-40

*Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden; †Division of Gastroenterology, Fondazione Tommaso Campanella, University Magna Graecia of Catanzaro, Catanzaro, Italy; ‡Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Policlinico, and DEPT, Università degli Studi di Milano, Milano, Italy; §Department of Medical and Surgical Sciences, Clinical Nutrition Unit, University Magna Graecia of Catanzaro, Catanzaro, Italy; ‖University Magna Graecia of Catanzaro, Catanzaro, Italy; ¶Unit of Gastroenterology, Fondazione IRCCS Ca' Granda-Ospedale Policlinico Milano, Milan, Italy; **Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy; and ††Cardiology Department, Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1097/MIB.0000000000000569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894778PMC
January 2016

Perianal Crohn's disease and fistula-associated carcinoma: challenges in diagnosis.

Int J Colorectal Dis 2015 Nov 3;30(11):1589-91. Epub 2015 Feb 3.

General and Emergency Surgery Unit, Ospedale Maggiore Policlinico, via F. Sforza 28, 20122, Milan, Italy.

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http://dx.doi.org/10.1007/s00384-015-2140-yDOI Listing
November 2015

The Role of Ultrasound Elasticity Imaging in Predicting Ileal Fibrosis in Crohn's Disease Patients.

Inflamm Bowel Dis 2015 Nov;21(11):2605-12

*Gastroenterology and Endoscopy Unit, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Milan, Italy; †Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy; ‡Pathology Unit, Fondazione IRCCS Cà Granda, Ospedale Policlinico di Milano, Milan, Italy; §Department of Biomedical and Clinical Sciences L. Sacco, Università degli Studi di Milano, Milan, Italy; and ‖General and Emergency Surgery Unit, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Milan, Italy.

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http://dx.doi.org/10.1097/MIB.0000000000000536DOI Listing
November 2015

A gut-vascular barrier controls the systemic dissemination of bacteria.

Science 2015 Nov;350(6262):830-4

Department of Experimental Oncology, European Institute of Oncology, Milan, Italy. Department of Biosciences, Università degli Studi di Milano, Italy.

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http://dx.doi.org/10.1126/science.aad0135DOI Listing
November 2015

Interleukin-34 sustains inflammatory pathways in the gut.

Clin Sci (Lond) 2015 Aug;129(3):271-80

*Department of Systems Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1042/CS20150132DOI Listing
August 2015

Dichotomy of short and long thymic stromal lymphopoietin isoforms in inflammatory disorders of the bowel and skin.

J Allergy Clin Immunol 2015 Aug 23;136(2):413-22. Epub 2015 May 23.

Department of Experimental Oncology, European Institute of Oncology, Milan, Italy; Dipartimento di Scienze della Salute, San Paolo, Università degli Studi di Milano, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534776PMC
August 2015

Surgery and diagnostic imaging in abdominal Crohn's disease.

J Ultrasound 2015 Mar 16;18(1):3-17. Epub 2013 Oct 16.

Unità Operativa di Chirurgia Generale e d'Urgenza, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy ; Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Università degli Studi di Milano, Milan, Italy.

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http://dx.doi.org/10.1007/s40477-013-0037-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353831PMC
March 2015

Mongersen, an oral SMAD7 antisense oligonucleotide, and Crohn's disease.

N Engl J Med 2015 Mar;372(12):1104-13

From the Department of Systems Medicine, University of Tor Vergata (G.M., M.C.F., S.O., L.B., F.P.), Gastroenterology Unit-Azienda Ospedaliera San Camillo-Forlanini (M.L.S.), Inflammatory Bowel Disease Unit, Complesso Integrato Columbus, Catholic University (A.A.), and Inflammatory Bowel Disease Unit, Department of Internal Medicine, Division of Gastroenterology, Sandro Pertini Hospital Rome (R.P.), Rome, Department of Surgery, L. Sacco University Hospital (S.A., M.F.), Department of Pathophysiology and Transplantation, University of Milan and Ospedale Policlinico di Milano (F. Caprioli), and Department of Biomedical Sciences for Health, University of Milan, and Gastroenterology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Policlinico San Donato, San Donato Milanese (M.V.), Milan, First Department of Internal Medicine, St. Matteo Hospital Foundation, University of Pavia, Pavia (A.D.S., G.R.C.), Gastroenterologia, Università Federico II di Napoli, Naples (F. Castiglione), Dipartimento di Scienze Chirurgiche Oncologiche e Gastroenterologiche-Unita' Operativa di Gastroenterologia-Universita' degli Studi di Padova, Padua (G.C.S.), Department of Medical and Surgical Specialties, Gastroenterology SOD2, Azienda Ospedaliero Universitaria Careggi, Florence (F.R.), Division of Gastroenterology, Casa Sollievo Sofferenza Hospital, IRCCS, San Giovanni Rotondo (F.B.), Department of Internal Medicine, Gastroenterology and Hepatology Unit, University of Genoa, Genoa (V.S.), and the Division of Internal Medicine Villa Sofia-Cervello Hospital, University of Palermo, Palermo (A.O.) - all in Italy; and the Department of Medicine, Medical Clinic 1, University of Erlangen-Nürnberg, Erlangen, Germany (M.F.N., R.A.).

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http://dx.doi.org/10.1056/NEJMoa1407250DOI Listing
March 2015

Absence of a role for interleukin-13 in inflammatory bowel disease.

Eur J Immunol 2014 Feb;44(2):370-85

Centre for Immunology and Infectious Disease, Blizard Institute, Barts and the London School of Medicine and Dentistry, London, UK; Department of Internal Medicine, S. Matteo Hospital, Centro per lo Studio e la Cura delle Malattie Infiammatorie Croniche Intestinali, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1002/eji.201343524DOI Listing
February 2014

Helicobacter pylori infection associates with a mucosal downregulation of ghrelin, negative regulator of Th1-cell responses.

Helicobacter 2013 Dec 19;18(6):406-12. Epub 2013 Jul 19.

Department of System Medicine, University of Rome "Tor Vergata", Viale Oxford 81, Rome, 00133, Italy.

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http://dx.doi.org/10.1111/hel.12065DOI Listing
December 2013

Investigational cytokine-targeted therapies for ulcerative colitis.

Expert Opin Investig Drugs 2013 Sep 27;22(9):1123-32. Epub 2013 Jun 27.

University of Rome "Tor Vergata", Department of Systems Medicine, Via Montpellier 1, Rome, 00133, Italy.

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http://dx.doi.org/10.1517/13543784.2013.813931DOI Listing
September 2013

A novel method for the culture and polarized stimulation of human intestinal mucosa explants.

J Vis Exp 2013 May 1(75):e4368. Epub 2013 May 1.

Department of Experimental Oncology, European Institute of Oncology.

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http://dx.doi.org/10.3791/4368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667689PMC
May 2013

Thrombotic storm in a teenager with previously undiagnosed ulcerative colitis.

Pediatrics 2013 Apr 4;131(4):e1288-91. Epub 2013 Mar 4.

UO Chirurgia Generale e Trapianti di Fegato Fondazione IRCCS Ca'Granda, Ospedale Maggiore Policlinico, Via F. Sforza 35, 20122 Milan, Italy.

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http://dx.doi.org/10.1542/peds.2012-2365DOI Listing
April 2013

Probiotic and postbiotic activity in health and disease: comparison on a novel polarised ex-vivo organ culture model.

Gut 2012 Jul 1;61(7):1007-15. Epub 2012 Feb 1.

Department of Experimental Oncology, European Institute of Oncology, Milan, Italy.

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http://dx.doi.org/10.1136/gutjnl-2011-300971DOI Listing
July 2012

Disruption of inflammatory signals by cytokine-targeted therapies for inflammatory bowel diseases.

Br J Pharmacol 2012 Feb;165(4):820-8

Unit of Gastroenterology 2, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan, Italy.

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http://dx.doi.org/10.1111/j.1476-5381.2011.01614.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312480PMC
February 2012

Incidence and clinical outcomes of intersphincteric abscesses diagnosed by anal ultrasonography in patients with crohn's disease.

Inflamm Bowel Dis 2011 Oct 6;17(10):2102-8. Epub 2011 Jan 6.

Department of Medical Sciences, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1002/ibd.21596DOI Listing
October 2011

Cytokine therapies in Crohn's disease: where are we now and where should we go?

Inflamm Allergy Drug Targets 2011 Feb;10(1):47-53

Dipartimento di Medicina, Interna, Università Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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February 2011

T-cell-directed therapies in inflammatory bowel diseases.

Clin Sci (Lond) 2010 Mar 30;118(12):707-15. Epub 2010 Mar 30.

Department of Internal Medicine, University Tor Vergata of Rome, Rome, Italy.

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http://dx.doi.org/10.1042/CS20100027DOI Listing
March 2010

Plasma chromogranin a in patients with inflammatory bowel disease.

Inflamm Bowel Dis 2009 Jun;15(6):867-71

Gastroenterology Unit II, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1002/ibd.20851DOI Listing
June 2009

Th17 immune response in IBD: A new pathogenic mechanism.

J Crohns Colitis 2008 Dec 25;2(4):291-5. Epub 2008 Jun 25.

Department of Internal Medicine & Centre of Excellence for Genomic Risk Assessment in Multifactorial and Complex Diseases, University "Tor Vergata" of Rome, Rome, Italy.

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https://academic.oup.com/ecco-jcc/article-lookup/doi/10.1016
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http://dx.doi.org/10.1016/j.crohns.2008.05.004DOI Listing
December 2008

Why are molecular mechanisms of immune activation important in IBD?

Inflamm Bowel Dis 2008 Oct;14 Suppl 2:S106-7

Department of Internal Medicine, University Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1002/ibd.20678DOI Listing
October 2008

Regulation of gut inflammation and th17 cell response by interleukin-21.

Gastroenterology 2008 Apr 17;134(4):1038-48. Epub 2008 Jan 17.

Dipartimento di Medicina Interna e Centro di Eccellenza per lo studio delle malattie complesse e multifattoriali, Università Tor Vergata, Rome.

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http://dx.doi.org/10.1053/j.gastro.2008.01.041DOI Listing
April 2008

Cyclooxygenase-2-dependent and -independent inhibition of proliferation of colon cancer cells by 5-aminosalicylic acid.

Biochem Pharmacol 2008 Feb 29;75(3):668-76. Epub 2007 Sep 29.

Dipartimento di Medicina Interna, Università Tor Vergata, Via Montpellier, 1-00133 Rome, Italy.

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http://dx.doi.org/10.1016/j.bcp.2007.09.020DOI Listing
February 2008

IL-23-mediated regulation of IL-17 production in Helicobacter pylori-infected gastric mucosa.

Eur J Immunol 2008 Feb;38(2):470-8

Department of Internal Medicine and Centre of Excellence for Genomic Risk Assessment in Multifactorial and Complex Diseases, University Tor Vergata of Rome, Rome, Italy.

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http://dx.doi.org/10.1002/eji.200737635DOI Listing
February 2008

Autocrine regulation of IL-21 production in human T lymphocytes.

J Immunol 2008 Feb;180(3):1800-7

Department of Internal Medicine, University Tor Vergata, Via Montpellier 1, Rome, Italy.

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http://dx.doi.org/10.4049/jimmunol.180.3.1800DOI Listing
February 2008

Drug evaluation: TA-2711E in the treatment of active distal ulcerative colitis.

Curr Opin Investig Drugs 2007 May;8(5):423-8

Università Tor Vergata, Dipartimento di Medicina Interna, Via Montpellier, 1, 00133 Rome, Italy.

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May 2007

A functional role for interleukin-21 in promoting the synthesis of the T-cell chemoattractant, MIP-3alpha, by gut epithelial cells.

Gastroenterology 2007 Jan 1;132(1):166-75. Epub 2006 Oct 1.

Dipartimento di Medicina Interna e Centro di Eccellenza, Studio delle Malattie Complesse e Multifattoriali, Università Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1053/j.gastro.2006.09.053DOI Listing
January 2007

Computer-assisted evaluation of perianal fistula activity by means of anal ultrasound in patients with Crohn's disease.

Am J Gastroenterol 2006 Jul;101(7):1551-8

Post-graduate School of Gastroenterology and Digestive Endoscopy (I), University of Milan, Milan, Italy.

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http://dx.doi.org/10.1111/j.1572-0241.2006.00561.xDOI Listing
July 2006