Publications by authors named "Flavia de Lima Alves"

29Publications

The Proteomic Landscape of Centromeric Chromatin Reveals an Essential Role for the Ctf19 Complex in Meiotic Kinetochore Assembly.

Authors:
Weronika E Borek Nadine Vincenten Eris Duro Vasso Makrantoni Christos Spanos Krishna K Sarangapani Flavia de Lima Alves David A Kelly Charles L Asbury Juri Rappsilber Adele L Marston

Curr Biol 2020 Oct 31. Epub 2020 Oct 31.

The Wellcome Centre for Cell Biology, Institute of Cell Biology, School of Biological Sciences, Michael Swann Building, Max Born Crescent, Edinburgh EH9 3BF, UK. Electronic address:

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October 2020

RNA polymerase II stalling at pre-mRNA splice sites is enforced by ubiquitination of the catalytic subunit.

Authors:
Laura Milligan Camille Sayou Alex Tuck Tatsiana Auchynnikava Jane Ea Reid Ross Alexander Flavia de Lima Alves Robin Allshire Christos Spanos Juri Rappsilber Jean D Beggs Grzegorz Kudla David Tollervey

Elife 2017 10 13;6. Epub 2017 Oct 13.

Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, Scotland.

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October 2017

Proteomics Analysis with a Nano Random Forest Approach Reveals Novel Functional Interactions Regulated by SMC Complexes on Mitotic Chromosomes.

Authors:
Shinya Ohta Luis F Montaño-Gutierrez Flavia de Lima Alves Hiromi Ogawa Iyo Toramoto Nobuko Sato Ciaran G Morrison Shunichi Takeda Damien F Hudson Juri Rappsilber William C Earnshaw

Mol Cell Proteomics 2016 08 26;15(8):2802-18. Epub 2016 May 26.

§Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Mayfield Road, Edinburgh EH9 3BF, UK;

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August 2016

G9a/GLP Complex Maintains Imprinted DNA Methylation in Embryonic Stem Cells.

Authors:
Tuo Zhang Ausma Termanis Burak Özkan Xun X Bao Jayne Culley Flavia de Lima Alves Juri Rappsilber Bernard Ramsahoye Irina Stancheva

Cell Rep 2016 Apr 24;15(1):77-85. Epub 2016 Mar 24.

Wellcome Trust Centre for Cell Biology, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh EH9 3BF, UK. Electronic address:

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April 2016

Correction: Kicking against the PRCs--A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2.

Authors:
Shih Chieh Liang Ben Hartwig Pumi Perera Santiago Mora-García Erica de Leau Harry Thornton Flavia de Lima Alves Juri Rappsilber Suxin Yang Geo Velikkakam James Korbinian Schneeberger E Jean Finnegan Franziska Turck Justin Goodrich

PLoS Genet 2016 Feb 19;12(2):e1005812. Epub 2016 Feb 19.

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February 2016

Whole-proteome genetic analysis of dependencies in assembly of a vertebrate kinetochore.

Authors:
Itaru Samejima Christos Spanos Flavia de Lima Alves Tetsuya Hori Marinela Perpelescu Juan Zou Juri Rappsilber Tatsuo Fukagawa William C Earnshaw

J Cell Biol 2015 Dec 14;211(6):1141-56. Epub 2015 Dec 14.

Wellcome Trust Centre for Cell Biology, Institute of Cell Biology, University of Edinburgh, Edinburgh EH9 3BF, Scotland, UK

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December 2015

Kicking against the PRCs - A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2.

Authors:
Shih Chieh Liang Ben Hartwig Pumi Perera Santiago Mora-García Erica de Leau Harry Thornton Flavia de Lima Alves Flavia Lima de Alves Juri Rappsilber Juri Rapsilber Suxin Yang Geo Velikkakam James Korbinian Schneeberger E Jean Finnegan Franziska Turck Justin Goodrich

PLoS Genet 2015 Dec 7;11(12):e1005660. Epub 2015 Dec 7.

Institute of Molecular Plant Science, University of Edinburgh, Edinburgh, United Kingdom.

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December 2015

Mto2 multisite phosphorylation inactivates non-spindle microtubule nucleation complexes during mitosis.

Authors:
Weronika E Borek Lynda M Groocock Itaru Samejima Juan Zou Flavia de Lima Alves Juri Rappsilber Kenneth E Sawin

Nat Commun 2015 Aug 5;6:7929. Epub 2015 Aug 5.

Wellcome Trust Centre for Cell Biology, Institute of Cell Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh EH9 3BF, UK.

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August 2015

Concomitant osmotic and chaotropicity-induced stresses in Aspergillus wentii: compatible solutes determine the biotic window.

Authors:
Flávia de Lima Alves Andrew Stevenson Esther Baxter Jenny L M Gillion Fakhrossadat Hejazi Sandra Hayes Ian E G Morrison Bernard A Prior Terry J McGenity Drauzio E N Rangel Naresh Magan Kenneth N Timmis John E Hallsworth

Curr Genet 2015 Aug 9;61(3):457-77. Epub 2015 Jun 9.

Department of Biological Sciences, University of Essex, Colchester, CO4 3SQ, UK.

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August 2015

A systematic genetic screen identifies new factors influencing centromeric heterochromatin integrity in fission yeast.

Authors:
Elizabeth H Bayne Dominika A Bijos Sharon A White Flavia de Lima Alves Juri Rappsilber Robin C Allshire

Genome Biol 2014 ;15(10):481

Institute of Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh EH9 3JR, UK.

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October 2015

Sister kinetochores are mechanically fused during meiosis I in yeast.

Authors:
Krishna K Sarangapani Eris Duro Yi Deng Flavia de Lima Alves Qiaozhen Ye Kwaku N Opoku Steven Ceto Juri Rappsilber Kevin D Corbett Sue Biggins Adèle L Marston Charles L Asbury

Science 2014 Oct 11;346(6206):248-51. Epub 2014 Sep 11.

Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195, USA.

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October 2014

Supraspliceosomes at defined functional states portray the pre-assembled nature of the pre-mRNA processing machine in the cell nucleus.

Authors:
Hani Kotzer-Nevo Flavia de Lima Alves Juri Rappsilber Joseph Sperling Ruth Sperling

Int J Mol Sci 2014 Jun 30;15(7):11637-64. Epub 2014 Jun 30.

Department of Genetics, the Hebrew University of Jerusalem, Jerusalem 91904, Israel.

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June 2014

Pom1 regulates the assembly of Cdr2-Mid1 cortical nodes for robust spatial control of cytokinesis.

Authors:
Sergio A Rincon Payal Bhatia Claudia Bicho Mercè Guzman-Vendrell Vincent Fraisier Weronika E Borek Flavia de Lima Alves Florent Dingli Damarys Loew Juri Rappsilber Kenneth E Sawin Sophie G Martin Anne Paoletti

J Cell Biol 2014 Jul 30;206(1):61-77. Epub 2014 Jun 30.

Centre de Recherche and Laboratory of Mass Spectrometry and Proteomics, Institut Curie, F-75248 Paris, France Centre National de la Recherche Scientifique, Unite Mixte de Recherche 144, F-75248 Paris, France

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July 2014

Lin28a regulates neuronal differentiation and controls miR-9 production.

Authors:
Jakub S Nowak Nila Roy Choudhury Flavia de Lima Alves Juri Rappsilber Gracjan Michlewski

Nat Commun 2014 Apr 11;5:3687. Epub 2014 Apr 11.

Wellcome Trust Centre for Cell Biology, University of Edinburgh, King's Buildings, Edinburgh EH9 3JR, UK.

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April 2014

Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components.

Authors:
Constance Alabert Jimi-Carlo Bukowski-Wills Sung-Bau Lee Georg Kustatscher Kyosuke Nakamura Flavia de Lima Alves Patrice Menard Jakob Mejlvang Juri Rappsilber Anja Groth

Nat Cell Biol 2014 Mar 23;16(3):281-93. Epub 2014 Feb 23.

Biotech Research and Innovation Centre (BRIC) and Centre for Epigenetics, University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen, Denmark.

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March 2014

Shugoshin biases chromosomes for biorientation through condensin recruitment to the pericentromere.

Authors:
Kitty F Verzijlbergen Olga O Nerusheva David Kelly Alastair Kerr Dean Clift Flavia de Lima Alves Juri Rappsilber Adele L Marston

Elife 2014 4;3:e01374. Epub 2014 Feb 4.

Wellcome Trust Centre for Cell Biology, Institute of Cell Biology, University of Edinburgh, Edinburgh, United Kingdom.

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February 2016

Rrp5 binding at multiple sites coordinates pre-rRNA processing and assembly.

Authors:
Simon Lebaron Asa Segerstolpe Sarah L French Tatiana Dudnakova Flavia de Lima Alves Sander Granneman Juri Rappsilber Ann L Beyer Lars Wieslander David Tollervey

Mol Cell 2013 Dec 14;52(5):707-19. Epub 2013 Nov 14.

Wellcome Trust Centre for Cell Biology, University of Edinburgh, Michael Swann Building, Kings Buildings, Mayfield Road, Edinburgh EH9 3JR, Scotland. Electronic address:

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December 2013

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor.

Authors:
Matthew J Lyst Robert Ekiert Daniel H Ebert Cara Merusi Jakub Nowak Jim Selfridge Jacky Guy Nathaniel R Kastan Nathaniel D Robinson Flavia de Lima Alves Juri Rappsilber Michael E Greenberg Adrian Bird

Nat Neurosci 2013 Jul 16;16(7):898-902. Epub 2013 Jun 16.

The Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, UK.

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July 2013

Cohesin-dependent association of scc2/4 with the centromere initiates pericentromeric cohesion establishment.

Authors:
Josefin Fernius Olga O Nerusheva Stefan Galander Flavia de Lima Alves Juri Rappsilber Adele L Marston

Curr Biol 2013 Apr 14;23(7):599-606. Epub 2013 Mar 14.

The Wellcome Trust Centre for Cell Biology, School of Biological Sciences, Michael Swann Building, Mayfield Road, Edinburgh EH9 3JR, UK.

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April 2013

Tissue-specific control of brain-enriched miR-7 biogenesis.

Authors:
Nila Roy Choudhury Flavia de Lima Alves Luisa de Andrés-Aguayo Thomas Graf Javier F Cáceres Juri Rappsilber Gracjan Michlewski

Genes Dev 2013 Jan;27(1):24-38

Wellcome Trust Centre for Cell Biology, University of Edinburgh, United Kingdom.

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January 2013

Multiple RNA interactions position Mrd1 at the site of the small subunit pseudoknot within the 90S pre-ribosome.

Authors:
Åsa Segerstolpe Sander Granneman Petra Björk Flavia de Lima Alves Juri Rappsilber Charlotta Andersson Martin Högbom David Tollervey Lars Wieslander

Nucleic Acids Res 2013 Jan 27;41(2):1178-90. Epub 2012 Nov 27.

Department of Molecular Biology and Functional Genomics, Stockholm University SE-106 91, Stockholm, Sweden.

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January 2013

Mitotic chromosomes are compacted laterally by KIF4 and condensin and axially by topoisomerase IIα.

Authors:
Kumiko Samejima Itaru Samejima Paola Vagnarelli Hiromi Ogawa Giulia Vargiu David A Kelly Flavia de Lima Alves Alastair Kerr Lydia C Green Damien F Hudson Shinya Ohta Carol A Cooke Christine J Farr Juri Rappsilber William C Earnshaw

J Cell Biol 2012 Nov 19;199(5):755-70. Epub 2012 Nov 19.

Wellcome Trust Centre for Cell Biology, University of Edinburgh, King's Buildings, Edinburgh EH9 3JR, Scotland, UK.

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November 2012

Raf1 Is a DCAF for the Rik1 DDB1-like protein and has separable roles in siRNA generation and chromatin modification.

Authors:
Alessia Buscaino Sharon A White Douglas R Houston Erwan Lejeune Femke Simmer Flavia de Lima Alves Piyush T Diyora Takeshi Urano Elizabeth H Bayne Juri Rappsilber Robin C Allshire

PLoS Genet 2012 Feb 2;8(2):e1002499. Epub 2012 Feb 2.

Wellcome Trust Centre for Cell Biology, School of Biological Sciences, The University of Edinburgh, United Kingdom.

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February 2012

Repo-Man coordinates chromosomal reorganization with nuclear envelope reassembly during mitotic exit.

Authors:
Paola Vagnarelli Susana Ribeiro Lau Sennels Luis Sanchez-Pulido Flavia de Lima Alves Toon Verheyen David A Kelly Chris P Ponting Juri Rappsilber William C Earnshaw

Dev Cell 2011 Aug 4;21(2):328-42. Epub 2011 Aug 4.

Wellcome Trust Centre for Cell Biology, Institute of Cell Biology, University of Edinburgh, Edinburgh EH9 3JR, UK.

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August 2011

The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics.

Authors:
Shinya Ohta Jimi-Carlo Bukowski-Wills Luis Sanchez-Pulido Flavia de Lima Alves Laura Wood Zhuo A Chen Melpi Platani Lutz Fischer Damien F Hudson Chris P Ponting Tatsuo Fukagawa William C Earnshaw Juri Rappsilber

Cell 2010 Sep;142(5):810-21

Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3JR, UK.

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September 2010

A genetic engineering solution to the "arginine conversion problem" in stable isotope labeling by amino acids in cell culture (SILAC).

Authors:
Claudia C Bicho Flavia de Lima Alves Zhuo A Chen Juri Rappsilber Kenneth E Sawin

Mol Cell Proteomics 2010 Jul 10;9(7):1567-77. Epub 2010 May 10.

Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3JR, United Kingdom.

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July 2010

Arginine methylation of vasa protein is conserved across phyla.

Authors:
Yohei Kirino Anastassios Vourekas Namwoo Kim Flavia de Lima Alves Juri Rappsilber Peter S Klein Thomas A Jongens Zissimos Mourelatos

J Biol Chem 2010 Mar 15;285(11):8148-54. Epub 2010 Jan 15.

Department of Pathology and Laboratory Medicine, Division of Neuropathology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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March 2010

Arginine methylation of Aubergine mediates Tudor binding and germ plasm localization.

Authors:
Yohei Kirino Anastassios Vourekas Nabil Sayed Flavia de Lima Alves Travis Thomson Paul Lasko Juri Rappsilber Thomas A Jongens Zissimos Mourelatos

RNA 2010 Jan 19;16(1):70-8. Epub 2009 Nov 19.

Division of Neuropathology, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine,Philadelphia, Pennsylvania 19104, USA.

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January 2010

Limits of life in MgCl2-containing environments: chaotropicity defines the window.

Authors:
John E Hallsworth Michail M Yakimov Peter N Golyshin Jenny L M Gillion Giuseppe D'Auria Flavia de Lima Alves Violetta La Cono Maria Genovese Boyd A McKew Sandra L Hayes Gayle Harris Laura Giuliano Kenneth N Timmis Terry J McGenity

Environ Microbiol 2007 Mar;9(3):801-13

Department of Biological Sciences, University of Essex, Colchester, CO4 3SQ, UK.

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March 2007