Publications by authors named "Flavia de Lima Alves"

29Publications

The Proteomic Landscape of Centromeric Chromatin Reveals an Essential Role for the Ctf19 Complex in Meiotic Kinetochore Assembly.

Curr Biol 2020 Oct 31. Epub 2020 Oct 31.

The Wellcome Centre for Cell Biology, Institute of Cell Biology, School of Biological Sciences, Michael Swann Building, Max Born Crescent, Edinburgh EH9 3BF, UK. Electronic address:

View Article and Find Full Text PDF
October 2020

Proteomics Analysis with a Nano Random Forest Approach Reveals Novel Functional Interactions Regulated by SMC Complexes on Mitotic Chromosomes.

Mol Cell Proteomics 2016 08 26;15(8):2802-18. Epub 2016 May 26.

§Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Mayfield Road, Edinburgh EH9 3BF, UK;

View Article and Find Full Text PDF
August 2016

G9a/GLP Complex Maintains Imprinted DNA Methylation in Embryonic Stem Cells.

Cell Rep 2016 Apr 24;15(1):77-85. Epub 2016 Mar 24.

Wellcome Trust Centre for Cell Biology, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh EH9 3BF, UK. Electronic address:

View Article and Find Full Text PDF
April 2016

Whole-proteome genetic analysis of dependencies in assembly of a vertebrate kinetochore.

J Cell Biol 2015 Dec 14;211(6):1141-56. Epub 2015 Dec 14.

Wellcome Trust Centre for Cell Biology, Institute of Cell Biology, University of Edinburgh, Edinburgh EH9 3BF, Scotland, UK

View Article and Find Full Text PDF
December 2015

Mto2 multisite phosphorylation inactivates non-spindle microtubule nucleation complexes during mitosis.

Nat Commun 2015 Aug 5;6:7929. Epub 2015 Aug 5.

Wellcome Trust Centre for Cell Biology, Institute of Cell Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh EH9 3BF, UK.

View Article and Find Full Text PDF
August 2015

A systematic genetic screen identifies new factors influencing centromeric heterochromatin integrity in fission yeast.

Genome Biol 2014 ;15(10):481

Institute of Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh EH9 3JR, UK.

View Article and Find Full Text PDF
October 2015

Sister kinetochores are mechanically fused during meiosis I in yeast.

Science 2014 Oct 11;346(6206):248-51. Epub 2014 Sep 11.

Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195, USA.

View Article and Find Full Text PDF
October 2014

Supraspliceosomes at defined functional states portray the pre-assembled nature of the pre-mRNA processing machine in the cell nucleus.

Int J Mol Sci 2014 Jun 30;15(7):11637-64. Epub 2014 Jun 30.

Department of Genetics, the Hebrew University of Jerusalem, Jerusalem 91904, Israel.

View Article and Find Full Text PDF
June 2014

Pom1 regulates the assembly of Cdr2-Mid1 cortical nodes for robust spatial control of cytokinesis.

J Cell Biol 2014 Jul 30;206(1):61-77. Epub 2014 Jun 30.

Centre de Recherche and Laboratory of Mass Spectrometry and Proteomics, Institut Curie, F-75248 Paris, France Centre National de la Recherche Scientifique, Unite Mixte de Recherche 144, F-75248 Paris, France

View Article and Find Full Text PDF
July 2014

Lin28a regulates neuronal differentiation and controls miR-9 production.

Nat Commun 2014 Apr 11;5:3687. Epub 2014 Apr 11.

Wellcome Trust Centre for Cell Biology, University of Edinburgh, King's Buildings, Edinburgh EH9 3JR, UK.

View Article and Find Full Text PDF
April 2014

Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components.

Nat Cell Biol 2014 Mar 23;16(3):281-93. Epub 2014 Feb 23.

Biotech Research and Innovation Centre (BRIC) and Centre for Epigenetics, University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen, Denmark.

View Article and Find Full Text PDF
March 2014

Shugoshin biases chromosomes for biorientation through condensin recruitment to the pericentromere.

Elife 2014 4;3:e01374. Epub 2014 Feb 4.

Wellcome Trust Centre for Cell Biology, Institute of Cell Biology, University of Edinburgh, Edinburgh, United Kingdom.

View Article and Find Full Text PDF
February 2016

Rrp5 binding at multiple sites coordinates pre-rRNA processing and assembly.

Mol Cell 2013 Dec 14;52(5):707-19. Epub 2013 Nov 14.

Wellcome Trust Centre for Cell Biology, University of Edinburgh, Michael Swann Building, Kings Buildings, Mayfield Road, Edinburgh EH9 3JR, Scotland. Electronic address:

View Article and Find Full Text PDF
December 2013

Cohesin-dependent association of scc2/4 with the centromere initiates pericentromeric cohesion establishment.

Curr Biol 2013 Apr 14;23(7):599-606. Epub 2013 Mar 14.

The Wellcome Trust Centre for Cell Biology, School of Biological Sciences, Michael Swann Building, Mayfield Road, Edinburgh EH9 3JR, UK.

View Article and Find Full Text PDF
April 2013

Multiple RNA interactions position Mrd1 at the site of the small subunit pseudoknot within the 90S pre-ribosome.

Nucleic Acids Res 2013 Jan 27;41(2):1178-90. Epub 2012 Nov 27.

Department of Molecular Biology and Functional Genomics, Stockholm University SE-106 91, Stockholm, Sweden.

View Article and Find Full Text PDF
January 2013

Repo-Man coordinates chromosomal reorganization with nuclear envelope reassembly during mitotic exit.

Dev Cell 2011 Aug 4;21(2):328-42. Epub 2011 Aug 4.

Wellcome Trust Centre for Cell Biology, Institute of Cell Biology, University of Edinburgh, Edinburgh EH9 3JR, UK.

View Article and Find Full Text PDF
August 2011

A genetic engineering solution to the "arginine conversion problem" in stable isotope labeling by amino acids in cell culture (SILAC).

Mol Cell Proteomics 2010 Jul 10;9(7):1567-77. Epub 2010 May 10.

Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3JR, United Kingdom.

View Article and Find Full Text PDF
July 2010

Arginine methylation of vasa protein is conserved across phyla.

J Biol Chem 2010 Mar 15;285(11):8148-54. Epub 2010 Jan 15.

Department of Pathology and Laboratory Medicine, Division of Neuropathology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

View Article and Find Full Text PDF
March 2010

Arginine methylation of Aubergine mediates Tudor binding and germ plasm localization.

RNA 2010 Jan 19;16(1):70-8. Epub 2009 Nov 19.

Division of Neuropathology, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine,Philadelphia, Pennsylvania 19104, USA.

View Article and Find Full Text PDF
January 2010