Publications by authors named "Flavia Caime"

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Thalidomide for de novo Crohn's disease after ileal pouch anal anastomosis for ulcerative colitis.

J Clin Pharm Ther 2020 Aug 16;45(4):819-821. Epub 2020 Apr 16.

Unit of Pediatric Gastroenterology and Cystic Fibrosis, Department of Human Pathology in Adulthood and Childhood "G. Barresi", University of Messina, Messina, Italy.

What Is Known And The Objective: De novo Crohn's disease (CD) is an increasingly reported diagnosis after ileal pouch anal anastomosis (IPAA). Currently, no consensus exists on the best treatment strategy.

Case Summary: This report details the case of a 5-year-old child with early-onset ulcerative colitis (UC) who developed findings compatible with CD 12 months after IPAA. Thalidomide therapy led to clinical and endoscopic remission without side effects at 6 months.

What Is New And Conclusion: To our knowledge, this is the first report of thalidomide for treatment of de novo CD. Thalidomide therapy could be considered in patients with de novo CD, with similar indications of CD.
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http://dx.doi.org/10.1111/jcpt.13140DOI Listing
August 2020