Fiorenza Orlando

Fiorenza Orlando

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Fiorenza Orlando

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Induction of Mouse Lung Injury by Endotracheal Injection of Bleomycin.

J Vis Exp 2019 Apr 30(146). Epub 2019 Apr 30.

Dipartimento di Scienze Cliniche e Molecolari, Università Politecnica delle Marche;

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http://dx.doi.org/10.3791/58922DOI Listing
April 2019

In vitro and in vivo activity of fosfomycin alone and in combination with rifampin and tigecycline against Gram-positive cocci isolated from surgical wound infections.

J Med Microbiol 2018 Jan 20;67(1):139-143. Epub 2017 Nov 20.

2​Infectious Diseases Clinic, Department of Biomedical Sciences and Public Health, Polytechnic University of Marche, Ancona, Italy.

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http://dx.doi.org/10.1099/jmm.0.000649DOI Listing
January 2018

Increase of n-NOS and i-NOS in Rat Colon After Sacral Neuromodulation.

Neuromodulation 2017 Dec 24;20(8):761-766. Epub 2017 Aug 24.

Clinical Surgery, Università Politecnica delle Marche - Ospedali Riuniti, Ancona, Italy.

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http://dx.doi.org/10.1111/ner.12644DOI Listing
December 2017

Supplementation with tocotrienols from Bixa orellana improves the in vivo efficacy of daptomycin against methicillin-resistant Staphylococcus aureus in a mouse model of infected wound.

Phytomedicine 2017 Dec 27;36:50-53. Epub 2017 Sep 27.

Advanced Technology Center for Aging Research, Scientific Technological Area, IRCCS-INRCA, Via Birarelli 8, Ancona 60121, Italy; Experimental Animal Models for Aging Unit, Scientific Technological Area, IRCCS-INRCA, Via Birarelli 8, Ancona 60121, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2017.09.011DOI Listing
December 2017

Booster immunizations with DNA plasmids encoding HER-2/neu prevent spontaneous mammary cancer in HER-2/neu transgenic mice over life span.

Sci Rep 2017 06 8;7(1):3078. Epub 2017 Jun 8.

Advanced Technology Center for Aging Research, Scientific Technological Area, IRCCS-INRCA, Ancona, Italy.

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http://dx.doi.org/10.1038/s41598-017-03286-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465096PMC
June 2017

Effect of hyperglycemia on the number of CD117 progenitor cells and their differentiation toward endothelial progenitor cells in young and old ages.

Mech Ageing Dev 2016 10 11;159:31-36. Epub 2016 Feb 11.

Advanced Technology Center for Aging Research, Scientific Technological Area, IRCCS-INRCA, Ancona, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.mad.2016.02.006DOI Listing
October 2016

Enhanced Efficacy of Combinations of Pexiganan with Colistin Versus Acinetobacter Baumannii in Experimental Sepsis.

Shock 2016 08;46(2):219-25

*Institute of Infectious Diseases and Public Health, Università Politecnica delle Marche, Ancona, Italy †Clinic of Dermatology, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy ‡Experimental Animal Models for Aging Unit, Scientific Technological Area, I.N.R.C.A. I.R.R.C.S., Ancona, Italy §General Surgery and Surgery Methodology Clinic, Università Politecnica delle Marche, Ancona, Italy ||Clinic of Urology, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy.

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http://dx.doi.org/10.1097/SHK.0000000000000584DOI Listing
August 2016

Antiangiogenic and antitumor activities of berberine derivative NAX014 compound in a transgenic murine model of HER2/neu-positive mammary carcinoma.

Carcinogenesis 2015 Oct 13;36(10):1169-79. Epub 2015 Jul 13.

Advanced Technology Center for Aging Research, Scientific Technological Area, IRCCS- INRCA, Via Birarelli 8, 60121 Ancona, Italy, Experimental Animal Models for Aging Unit, Scientific Technological Area, IRCCS- INRCA, via Birarelli 8, 60121 Ancona, Italy,

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http://dx.doi.org/10.1093/carcin/bgv103DOI Listing
October 2015

Sidestream dark field videomicroscopy for in vivo evaluation of vascularization and perfusion of mammary tumours in HER2/neu transgenic mice.

Clin Exp Pharmacol Physiol 2015 Feb;42(2):225-9

Anaesthesia and Intensive Care Unit, Department of Biomedical Sciences and Public Health, Polytechnic University of Marche, Ancona, Italy.

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http://dx.doi.org/10.1111/1440-1681.12343DOI Listing
February 2015

In vitro and in vivo effects of sub-MICs of pexiganan and imipenem on Pseudomonas aeruginosa adhesion and biofilm development.

Infez Med 2013 Dec;21(4):287-95

Clinic of Infectious Diseases, Universita Politecnica delle Marche, Ospedali Riuniti; General Surgery and Surgery Methodology Clinic, Universita Politecnica delle Marche, Ospedali Riuniti, Ancona, Italy; Faculty of Chemistry, University of Gdansk, Gdansk, Poland; Institute of Maternal and Childrens Sciences-Urology, Polytechnic University of the Marche Region, A.O. Ospedali Riuniti, Ancona, Italy; Experimental Animal Models for Aging Units, Research Department, I.N.R.C.A. I.R.R.C.S., Ancona, Italy; Faculty of Pharmacy, Medical University of Gdansk, Gdansk, Poland.

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December 2013

Effect of annatto-tocotrienols supplementation on the development of mammary tumors in HER-2/neu transgenic mice.

Carcinogenesis 2013 Jun 20;34(6):1352-60. Epub 2013 Feb 20.

Advanced Technology Center for Aging Research, Scientific Technological Area, IRCCS-INRCA, Via Birarelli 8, 60121 Ancona, Italy.

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http://dx.doi.org/10.1093/carcin/bgt064DOI Listing
June 2013

In vitro and in vivo effects of echinocandins against Candida parapsilosis sensu stricto, Candida orthopsilosis and Candida metapsilosis.

J Antimicrob Chemother 2012 Sep 25;67(9):2195-202. Epub 2012 May 25.

Department of Biomedical Sciences and Public Health, Clinic Infectious Disease, Università Politecnica delle Marche, Ancona, Italy.

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http://jac.oxfordjournals.org/content/early/2012/05/25/jac.d
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http://www.jac.oxfordjournals.org/cgi/doi/10.1093/jac/dks180
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http://dx.doi.org/10.1093/jac/dks180DOI Listing
September 2012

Nitric oxide synthase expression in rat anorectal tissue after sacral neuromodulation.

J Surg Res 2012 Jul 5;176(1):29-33. Epub 2011 Jul 5.

General Surgery and Surgery Methodology Clinic, Università Politecnica delle Marche-Ospedali Riuniti, Ancona, Italy.

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http://dx.doi.org/10.1016/j.jss.2011.06.005DOI Listing
July 2012

In vivo electroporation restores the low effectiveness of DNA vaccination against HER-2/neu in aging.

Cancer Immunol Immunother 2012 Mar 16;61(3):363-71. Epub 2011 Sep 16.

Advanced Technology Center for Aging Research, Scientific Technological Area, INRCA-IRCCS, Via Birarelli 8, 60121, Ancona, Italy.

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http://dx.doi.org/10.1007/s00262-011-1107-2DOI Listing
March 2012

Comparative effects of micafungin, caspofungin, and anidulafungin against a difficult-to-treat fungal opportunistic pathogen, Candida glabrata.

Antimicrob Agents Chemother 2012 Mar 27;56(3):1215-22. Epub 2011 Dec 27.

Department of Biomedical Sciences and Public Health, Clinic Infectious Disease, Università Politecnica delle Marche, Ancona, Italy.

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http://aac.asm.org/lookup/doi/10.1128/AAC.05872-11
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http://dx.doi.org/10.1128/AAC.05872-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294882PMC
March 2012

Why tocotrienols work better: insights into the in vitro anti-cancer mechanism of vitamin E.

Genes Nutr 2012 Jan 20;7(1):29-41. Epub 2011 Apr 20.

Department of Internal Medicine, Section of Applied Biochemistry and Nutritional Sciences, University of Perugia, Via del Giochetto, 06126, Perugia, Italy.

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http://dx.doi.org/10.1007/s12263-011-0219-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250530PMC
January 2012

Protective effect of citropin 1.1 and tazobactam-piperacillin against oxidative damage and lethality in mice models of gram-negative sepsis.

J Surg Res 2011 Dec 20;171(2):726-33. Epub 2010 Apr 20.

General Surgery and Surgery Methodology Clinic, Università Politecnica delle Marche, and Analysis Laboratory, Ospedali Riuniti Umberto I-Lancisi-Salesi, Ancona, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S00224804100025
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http://dx.doi.org/10.1016/j.jss.2010.03.055DOI Listing
December 2011

Vitamin E improves the in vivo efficacy of tigecycline and daptomycin in an animal model of wounds infected with meticillin-resistant Staphylococcus aureus.

J Med Microbiol 2011 Dec 11;60(Pt 12):1806-12. Epub 2011 Aug 11.

Experimental Animal Models for Aging Unit, Scientific Technological Area, INRCA-IRCCS, Università Politecnica delle Marche, Ancona, Italy.

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http://dx.doi.org/10.1099/jmm.0.032516-0DOI Listing
December 2011

In vitro and in vivo activities of posaconazole against zygomycetes with various degrees of susceptibility.

J Antimicrob Chemother 2010 Oct 28;65(10):2158-63. Epub 2010 Jul 28.

Dipartimento di Scienze Biomediche, Clinica Malattie Infettive, Università Politecnica delle Marche, Azienda Ospedaliero-Universitaria, Ospedali Riuniti Umberto I-Lancisi-Salesi, Via Conca, Torrette, Ancona 60020, Italy.

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http://dx.doi.org/10.1093/jac/dkq276DOI Listing
October 2010

Anidulafungin in combination with amphotericin B against Aspergillus fumigatus.

Antimicrob Agents Chemother 2009 Sep 13;53(9):4035-9. Epub 2009 Jul 13.

Dipartimento di Scienze Biomediche, Clinica di Malattie Infettive, Università Politecnica delle Marche, Ancona, Italy.

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http://dx.doi.org/10.1128/AAC.00659-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737837PMC
September 2009

Posaconazole against Candida glabrata isolates with various susceptibilities to fluconazole.

Antimicrob Agents Chemother 2008 Jun 7;52(6):1929-33. Epub 2008 Apr 7.

Istituto di Malattie Infettive e Medicina Pubblica, Università Politecnica delle Marche, Ancona, Italy.

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http://dx.doi.org/10.1128/AAC.00130-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2415808PMC
June 2008

Discovery of a quorum-sensing inhibitor of drug-resistant staphylococcal infections by structure-based virtual screening.

Mol Pharmacol 2008 May 26;73(5):1578-86. Epub 2008 Feb 26.

Department of Biomedical Sciences, Cummings School of Veterinary Medicine, Tufts University, 200 Westboro Rd., North Grafton, MA 01536, USA.

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http://dx.doi.org/10.1124/mol.107.044164DOI Listing
May 2008

Intrinsic and microenvironmental defects are involved in the age-related changes of Lin - c-kit+ hematopoietic progenitor cells.

Rejuvenation Res 2007 Dec;10(4):459-72

Immunology Center, INRCA Gerontology Research Department, Via Birarelli 8, Ancona, Italy.

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https://www.liebertpub.com/doi/10.1089/rej.2006.0524
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http://dx.doi.org/10.1089/rej.2006.0524DOI Listing
December 2007

RNAIII-inhibiting peptide affects biofilm formation in a rat model of staphylococcal ureteral stent infection.

Antimicrob Agents Chemother 2007 Dec 17;51(12):4518-20. Epub 2007 Sep 17.

Institute of Infectious Diseases and Public Health, Polytechnic University of the Marche Region, A.O. Ospedali Riuniti, Ancona, Italy.

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http://dx.doi.org/10.1128/AAC.00808-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2167994PMC
December 2007

Distinctin improves the efficacies of glycopeptides and betalactams against staphylococcal biofilm in an experimental model of central venous catheter infection.

J Biomed Mater Res A 2007 Apr;81(1):233-9

Institute of Infectious Diseases and Public Health, Università Politecnica delle Marche, c/o Ospedale Regionale, Via Conca 71, 60200 Ancona, Italy.

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http://dx.doi.org/10.1002/jbm.a.30982DOI Listing
April 2007

Experimental study on the efficacy of combination of alpha-helical antimicrobial peptides and vancomycin against Staphylococcus aureus with intermediate resistance to glycopeptides.

Peptides 2006 Nov 21;27(11):2600-6. Epub 2006 Jun 21.

Institute of Infectious Diseases and Public Health, Università Politecnica delle Marche, Clinica delle Malattie Infettive, c/o Ospedali Riuniti Ancona, Via Conca 71, 60200 Ancona AN, Italy.

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http://dx.doi.org/10.1016/j.peptides.2006.05.004DOI Listing
November 2006

RNAIII-inhibiting peptide in combination with the cathelicidin BMAP-28 reduces lethality in mouse models of staphylococcal sepsis.

Shock 2006 Sep;26(3):296-301

Department of General Surgery, Istituto Nazionale Riposo e Cura Anziani-Istituto di Ricovero e Cura a Carattere Scientifico, Università Politecnica delle Marche, Ancona, Italy.

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http://dx.doi.org/10.1097/01.shk.0000226336.02292.86DOI Listing
September 2006

Evaluation of different plasmid DNA delivery systems for immunization against HER2/neu in a transgenic murine model of mammary carcinoma.

Vaccine 2006 Mar 24;24(11):1766-75. Epub 2005 Oct 24.

Laboratory of Tumor Immunology, Immunology Center, INRCA Gerontology Research Department, Via Birarelli 8, 60121 Ancona, Italy.

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http://dx.doi.org/10.1016/j.vaccine.2005.10.022DOI Listing
March 2006

Mammary carcinoma provides highly tumourigenic and invasive reactive stromal cells.

Carcinogenesis 2005 Nov 23;26(11):1868-78. Epub 2005 Jun 23.

Department of Morphological and Biomedical Sciences, Section Anatomy and Histology, University of Verona, Verona, Italy.

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http://dx.doi.org/10.1093/carcin/bgi158DOI Listing
November 2005

Temporin A alone and in combination with imipenem reduces lethality in a mouse model of staphylococcal sepsis.

J Infect Dis 2005 Nov 27;192(9):1613-20. Epub 2005 Sep 27.

Institute of Infectious Diseases and Public Health, Department of General Surgery, Polytechnic University of Marche, Ancona, Italy.

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https://academic.oup.com/jid/article-lookup/doi/10.1086/4968
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http://dx.doi.org/10.1086/496888DOI Listing
November 2005

Effect of resveratrol on the development of spontaneous mammary tumors in HER-2/neu transgenic mice.

Int J Cancer 2005 May;115(1):36-45

Laboratory of Tumor Immunology, Immunology Center, Research Department, Italian National Research Centers on Aging (INRCA), Ancona, Italy.

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http://dx.doi.org/10.1002/ijc.20874DOI Listing
May 2005

BisEDT and RIP act in synergy to prevent graft infections by resistant staphylococci.

Peptides 2004 Dec;25(12):2047-53

Cardio Pulmonary Research Institute, Winthrop-University Hospital, SUNY Stony Brook School of Medicine, Mineola 11501, New York, NY, USA.

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http://dx.doi.org/10.1016/j.peptides.2004.08.005DOI Listing
December 2004

Therapeutic efficacy of the magainin analogue MSI-78 in different intra-abdominal sepsis rat models.

J Antimicrob Chemother 2004 Sep 4;54(3):654-60. Epub 2004 Aug 4.

Institute of Infectious Diseases and Public Health, Università Politecnica delle Marche, Ancona, Italy.

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http://dx.doi.org/10.1093/jac/dkh390DOI Listing
September 2004

Potential therapeutic role of histatin derivative P-113d in experimental rat models of Pseudomonas aeruginosa sepsis.

J Infect Dis 2004 Jul 21;190(2):356-64. Epub 2004 Jun 21.

Institute of Infectious Diseases and Public Health, National Institute for Research and Therapy in the Elderly, Universita Politecnica delle Marche, Ancona, Italy.

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http://dx.doi.org/10.1086/421913DOI Listing
July 2004

Metallothionein (I+II) confers, via c-myc, immune plasticity in oldest mice: model of partial hepatectomy/liver regeneration.

Mech Ageing Dev 2003 Aug-Sep;124(8-9):877-86

Immunology Ctr. (Section Nutrition Immunity and Ageing) Res. Dept., Italian National Centres on Ageing (I.N.R.C.A.), Via Birarelli 8, 60121 Ancona, Italy.

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http://dx.doi.org/10.1016/s0047-6374(03)00146-5DOI Listing
June 2004

Cathelicidin peptide sheep myeloid antimicrobial peptide-29 prevents endotoxin-induced mortality in rat models of septic shock.

Am J Respir Crit Care Med 2004 Jan 16;169(2):187-94. Epub 2003 Oct 16.

Institute of Infectious Diseases and Public Health, I.N.R.C.A. I.R.R.C.S., Università Politecnica delle Marche, Ancona, Italy.

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http://dx.doi.org/10.1164/rccm.200307-971OCDOI Listing
January 2004

Antiendotoxin activity of protegrin analog IB-367 alone or in combination with piperacillin in different animal models of septic shock.

Peptides 2003 Nov;24(11):1747-52

Institute of Infectious Diseases and Public Health, Clinica delle Malattie Infettive, Università Politecnica delle Marche, c/o Ospedale Regionale, Via Conca, 60020 Torrette AN, Ancona, Italy.

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http://dx.doi.org/10.1016/j.peptides.2003.07.027DOI Listing
November 2003