Fiorella Altruda

Fiorella Altruda

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Fiorella Altruda

Fiorella Altruda

Publications by authors named "Fiorella Altruda"

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Characterization of Human Mesenchymal Stem Cells Isolated from the Testis.

Stem Cells Int 2018 3;2018:4910304. Epub 2018 Sep 3.

Molecular Biotechnology Center, Department of Molecular Biotechnology and Health Sciences, University of Turin, Via Nizza 52, 10126 Turin, Italy.

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https://www.hindawi.com/journals/sci/2018/4910304/
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http://dx.doi.org/10.1155/2018/4910304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140008PMC
September 2018

Heme accumulation in endothelial cells impairs angiogenesis by triggering paraptosis.

Cell Death Differ 2018 Mar 11;25(3):573-588. Epub 2017 Dec 11.

Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino, Italy.

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http://dx.doi.org/10.1038/s41418-017-0001-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864215PMC
March 2018

Lack of Plasma Protein Hemopexin Results in Increased Duodenal Iron Uptake.

PLoS One 2013 27;8(6):e68146. Epub 2013 Jun 27.

Molecular Biotechnology Center, University of Torino, Torino, Italy ; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0068146PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694894PMC
October 2017

Hemopexin counteracts systolic dysfunction induced by heme-driven oxidative stress.

Free Radic Biol Med 2017 07 8;108:452-464. Epub 2017 Apr 8.

Dept. Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2017.04.003DOI Listing
July 2017

APL-1, an altered peptide ligand derived from heat-shock protein, alone or combined with methotrexate attenuates murine collagen-induced arthritis.

Clin Exp Med 2017 May 9;17(2):209-216. Epub 2016 May 9.

Biomedical Research Department, Center for Genetic Engineering and Biotechnology, P.O. Box 6162, 10600, Havana, Cuba.

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http://link.springer.com/10.1007/s10238-016-0412-7
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http://dx.doi.org/10.1007/s10238-016-0412-7DOI Listing
May 2017

Endoscopic imaging in the management of gastroenteropancreatic neuroendocrine tumors.

Minerva Endocrinol 2016 Dec;41(4):490-8

Department of Gastroenterology and Hepatology, Molinette Hospital, Turin, Italy -

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December 2016

Helicobacter pylori infection and ischemic heart disease: could experimental data lead to clinical studies?

Minerva Cardioangiol 2016 Dec 7;64(6):686-96. Epub 2016 Sep 7.

Unit of Gastroenterology, Molinette Hospital, Turin, Italy -

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December 2016

Prospects for Adult Stem Cells in the Treatment of Liver Diseases.

Stem Cells Dev 2016 Sep 7. Epub 2016 Sep 7.

2 Molecular Biotechnology Center, University of Turin , Turin, Italy .

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http://dx.doi.org/10.1089/scd.2016.0144DOI Listing
September 2016

Long Term Liver Engraftment of Functional Hepatocytes Obtained from Germline Cell-Derived Pluripotent Stem Cells.

PLoS One 2015 31;10(8):e0136762. Epub 2015 Aug 31.

Molecular Biotechnology Center, Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0136762PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556379PMC
June 2016

Alteration of heme metabolism in a cellular model of Diamond-Blackfan anemia.

Eur J Haematol 2016 Apr 25;96(4):367-74. Epub 2015 Jun 25.

Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino, Italy.

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http://dx.doi.org/10.1111/ejh.12599DOI Listing
April 2016

Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β -Globin Gene with the IVSI-6 Thalassemia Mutation.

Biomed Res Int 2015 4;2015:687635. Epub 2015 May 4.

Department of Life Sciences and Biotechnology, Biochemistry and Molecular Biology Section, Ferrara University, 44121 Ferrara, Italy ; Laboratory for the Development of Pharmacological and Pharmacogenomic Therapy of Thalassemia, Biotechnology Center, Ferrara University, 44121 Ferrara, Italy.

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http://dx.doi.org/10.1155/2015/687635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434229PMC
March 2016

Crucial Role of FLVCR1a in the Maintenance of Intestinal Heme Homeostasis.

Antioxid Redox Signal 2015 Dec 20;23(18):1410-23. Epub 2015 Jul 20.

1 Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino , Torino, Italy .

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http://dx.doi.org/10.1089/ars.2014.6216DOI Listing
December 2015

LSD1 Neurospecific Alternative Splicing Controls Neuronal Excitability in Mouse Models of Epilepsy.

Cereb Cortex 2015 Sep 15;25(9):2729-40. Epub 2014 Apr 15.

Department of Medical Biotechnology and Translational Medicine CNR, Institute of Neuroscience, Milan, Italy.

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http://dx.doi.org/10.1093/cercor/bhu070DOI Listing
September 2015

Hypoxia controls Flvcr1 gene expression in Caco2 cells through HIF2α and ETS1.

Biochim Biophys Acta 2014 24;1839(4):259-64. Epub 2014 Feb 24.

Molecular Biotechnology Center, University of Torino, 10126 Torino, Italy; Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbagrm.2014.02.010DOI Listing
June 2014

Heme exporter FLVCR1a regulates heme synthesis and degradation and controls activity of cytochromes P450.

Gastroenterology 2014 May 31;146(5):1325-38. Epub 2014 Jan 31.

Molecular Biotechnology Center and Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2014.01.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000440PMC
May 2014

Renal cells from spermatogonial germline stem cells protect against kidney injury.

J Am Soc Nephrol 2014 Feb 17;25(2):316-28. Epub 2013 Oct 17.

Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, and.

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http://dx.doi.org/10.1681/ASN.2013040367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904562PMC
February 2014

Acute-phase protein hemopexin is a negative regulator of Th17 response and experimental autoimmune encephalomyelitis development.

J Immunol 2013 Dec 23;191(11):5451-9. Epub 2013 Oct 23.

Department of Molecular Biotechnology and Health Sciences, University of Turin, 10126 Turin, Italy;

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http://dx.doi.org/10.4049/jimmunol.1203076DOI Listing
December 2013

Hemopexin therapy improves cardiovascular function by preventing heme-induced endothelial toxicity in mouse models of hemolytic diseases.

Circulation 2013 Mar 27;127(12):1317-29. Epub 2013 Feb 27.

Molecular Biotechnology Center and Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.112.130179DOI Listing
March 2013

Cell-specific regulation of Ferroportin transcription following experimentally-induced acute anemia in mice.

Blood Cells Mol Dis 2013 Jan 24;50(1):25-30. Epub 2012 Aug 24.

Dept. of Genetics, Biology and Biochemistry, University of Torino, Italy.

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http://dx.doi.org/10.1016/j.bcmd.2012.08.002DOI Listing
January 2013

Assessment of iron absorption in mice by ICP-MS measurements of (57)Fe levels.

Eur J Nutr 2012 Oct 19;51(7):783-9. Epub 2011 Oct 19.

Molecular Biotechnology Center, Department of Genetics, Biology and Biochemistry, University of Torino, Via Nizza 52, 10126, Turin, Italy.

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http://link.springer.com/content/pdf/10.1007/s00394-011-0256
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http://link.springer.com/10.1007/s00394-011-0256-6
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http://dx.doi.org/10.1007/s00394-011-0256-6DOI Listing
October 2012

Functional antagonism between Sall4 and Plzf defines germline progenitors.

Cell Stem Cell 2012 Mar;10(3):284-98

Cancer Genetics Program, Beth Israel Deaconess Cancer Center, Departments of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.stem.2012.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299297PMC
March 2012

The RacGAP ArhGAP15 is a master negative regulator of neutrophil functions.

Blood 2011 Jul 6;118(4):1099-108. Epub 2011 May 6.

Department of Genetic, Biology and Biochemistry, University of Torino, Torino, Italy.

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http://dx.doi.org/10.1182/blood-2010-12-324756DOI Listing
July 2011

Generation of functional hepatocytes from mouse germ line cell-derived pluripotent stem cells in vitro.

Stem Cells Dev 2010 Aug;19(8):1183-94

Department of Genetics, Biology and Biochemistry and Molecular Biotechnology Center, University of Turin, Turin, Italy.

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http://dx.doi.org/10.1089/scd.2009.0496DOI Listing
August 2010

Vascular endothelial growth factor (VEGF) in the pathogenesis of psoriasis--a possible target for novel therapies?

J Dermatol Sci 2010 Jun 9;58(3):171-6. Epub 2010 Apr 9.

Department of Dermatology and Allergy, Ludwig-Maximilian-University, 80337 Munich, Germany.

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http://dx.doi.org/10.1016/j.jdermsci.2010.03.023DOI Listing
June 2010

Therapeutic efficacy and immunological response of CCL5 antagonists in models of contact skin reaction.

PLoS One 2010 Jan 15;5(1):e8725. Epub 2010 Jan 15.

Department of Genetics, Biology and Biochemistry, University of Torino, Torino, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0008725PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806914PMC
January 2010

Heme-hemopexin complex attenuates neuronal cell death and stroke damage.

J Cereb Blood Flow Metab 2009 May 11;29(5):953-64. Epub 2009 Mar 11.

Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1038/jcbfm.2009.19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015738PMC
May 2009

Lack of plasma protein hemopexin dampens mercury-induced autoimmune response in mice.

J Immunol 2008 Aug;181(3):1937-47

Department of Genetics, Biology and Biochemistry, and Molecular Biotechnology Center, University of Turin, Turin, Italy.

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August 2008

Hemopexin prevents endothelial damage and liver congestion in a mouse model of heme overload.

Am J Pathol 2008 Jul 13;173(1):289-99. Epub 2008 Jun 13.

Molecular Biotechnology Center, Via Nizza 52, 10126 Torino, Italy.

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http://dx.doi.org/10.2353/ajpath.2008.071130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2438305PMC
July 2008

Lack of haptoglobin affects iron transport across duodenum by modulating ferroportin expression.

Gastroenterology 2007 Oct;133(4):1261-1271

Department of Genetics, Biology and Biochemistry, and Molecular Biotechnology Center, University of Torino, Torino, Italy.

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http://dx.doi.org/10.1053/j.gastro.2007.07.004DOI Listing
October 2007

Negative feedback regulation of Rac in leukocytes from mice expressing a constitutively active phosphatidylinositol 3-kinase gamma.

Proc Natl Acad Sci U S A 2007 Sep 24;104(36):14354-9. Epub 2007 Aug 24.

Dipartimento di Genetica, Biologia e Biochimica, Molecular Biotechnology Center, University of Torino, Via Nizza 52, 10126 Torino, Italy.

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http://dx.doi.org/10.1073/pnas.0703175104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952139PMC
September 2007

Hemoglobin and heme scavenging.

IUBMB Life 2005 Nov;57(11):749-59

National Institute for Infectious Diseases IRCCS 'Lazzaro Spallanzani', Roma, Italy.

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http://dx.doi.org/10.1080/15216540500380871DOI Listing
November 2005

Haptoglobin modifies the hemochromatosis phenotype in mice.

Blood 2005 Apr 21;105(8):3353-5. Epub 2004 Dec 21.

Department of Genetics, Biology and Biochemistry, University of Turin, Turin, Italy. emanuela.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2004-07-28
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http://dx.doi.org/10.1182/blood-2004-07-2814DOI Listing
April 2005

Plasma protein haptoglobin modulates renal iron loading.

Am J Pathol 2005 Apr;166(4):973-83

Department of Genetics, Biology and Biochemistry, University of Turin, Via Santena 5bis, 10126 Turin, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1602399PMC
http://dx.doi.org/10.1016/S0002-9440(10)62319-XDOI Listing
April 2005

Phosphoinositide 3-kinase gamma-deficient hearts are protected from the PAF-dependent depression of cardiac contractility.

Cardiovasc Res 2003 Nov;60(2):242-9

Dipartimento di Biologia Animale e dell'Uomo e Istituto Nazionale per la Fisica della Materia, Università di Torino, 10123 Torino, Italy.

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November 2003

Hmga2 promoter analysis in transgenic mice.

Biochem Biophys Res Commun 2003 Oct;309(4):718-23

Department of Biochemistry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, 675 Hoes Lane, Piscataway, NJ 08854, USA.

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October 2003

Role of citron kinase in dendritic morphogenesis of cortical neurons.

Brain Res Bull 2003 May;60(4):319-27

Department of Genetics, Biology and Biochemistry, University of Torino, Via Santena 5 bis, 10126, Torino, Italy.

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May 2003

Enhanced splenomegaly and severe liver inflammation in haptoglobin/hemopexin double-null mice after acute hemolysis.

Blood 2002 Dec 25;100(12):4201-8. Epub 2002 Jul 25.

Department of Genetics, Biology and Biochemistry, University of Turin and the San Giovanni Battista Hospital, Turin, Italy.

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http://dx.doi.org/10.1182/blood-2002-04-1270DOI Listing
December 2002

Essential role of citron kinase in cytokinesis of spermatogenic precursors.

J Cell Sci 2002 Dec;115(Pt 24):4819-26

Department of Genetics, Biology and Biochemistry, Via Santena 5 bis, Torino, Italy.

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December 2002

Regenerative and survival capabilities of Purkinje cells overexpressing c-Jun.

Eur J Neurosci 2002 Jul;16(1):105-18

Rita Levi-Montalcini Centre for Brain Repair, Department of Neuroscience, University of Turin, C. Raffaello 30, 10125 Turin, Italy.

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July 2002

Hemopexin: structure, function, and regulation.

DNA Cell Biol 2002 Apr;21(4):297-306

Department of Genetics, Biology and Biochemistry, University of Turin, 10126 Turin, Italy.

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http://dx.doi.org/10.1089/104454902753759717DOI Listing
April 2002

Phosphoinositide 3-kinase gamma is an essential amplifier of mast cell function.

Immunity 2002 Mar;16(3):441-51

Institute of Biochemistry, Department of Medicine, University of Fribourg, Rue du Musée 5, CH-1700 Fribourg, Switzerland.

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March 2002