Fiona Doetsch

Fiona Doetsch

UNVERIFIED PROFILE

Are you Fiona Doetsch?   Register this Author

Register author
Fiona Doetsch

Fiona Doetsch

Publications by authors named "Fiona Doetsch"

Are you Fiona Doetsch?   Register this Author

33Publications

489Reads

44Profile Views

FACS isolation of endothelial cells and pericytes from mouse brain microregions.

Nat Protoc 2018 04 22;13(4):738-751. Epub 2018 Mar 22.

Biozentrum, University of Basel, Basel, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nprot.2017.158DOI Listing
April 2018

Symmetric Stem Cell Division at the Heart of Adult Neurogenesis.

Neuron 2018 04;98(2):246-248

Biozentrum, University of Basel, Basel CH-4056, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuron.2018.04.005DOI Listing
April 2018

Molecular anatomy and functions of the choroidal blood-cerebrospinal fluid barrier in health and disease.

Acta Neuropathol 2018 03 24;135(3):337-361. Epub 2018 Jan 24.

Theodor Kocher Institute, University of Bern, Bern, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00401-018-1807-1DOI Listing
March 2018

FACS-based Isolation of Neural and Glioma Stem Cell Populations from Fresh Human Tissues Utilizing EGF Ligand.

Bio Protoc 2017 Dec;7(24)

Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21769/BioProtoc.2659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836493PMC
December 2017

Hypothalamic regulation of regionally distinct adult neural stem cells and neurogenesis.

Science 2017 06 15;356(6345):1383-1386. Epub 2017 Jun 15.

Department of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aal3839DOI Listing
June 2017

Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR Populations with Stem Cell Properties.

Stem Cell Reports 2017 05 20;8(5):1421-1429. Epub 2017 Apr 20.

Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Neuroscience, Friedman Brain Institute, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stemcr.2017.03.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425658PMC
May 2017

Age-Dependent Niche Signals from the Choroid Plexus Regulate Adult Neural Stem Cells.

Cell Stem Cell 2016 11 21;19(5):643-652. Epub 2016 Jul 21.

Biozentrum, University of Basel, 4056 Basel, Switzerland; Department of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA; Department of Neuroscience, Columbia University, New York, NY 10032, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2016.06.013DOI Listing
November 2016

A mosaic world: puzzles revealed by adult neural stem cell heterogeneity.

Wiley Interdiscip Rev Dev Biol 2016 11 20;5(6):640-658. Epub 2016 Sep 20.

Biozentrum, University of Basel, Basel, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/wdev.248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113677PMC
November 2016

EGFR promoter exhibits dynamic histone modifications and binding of ASH2L and P300 in human germinal matrix and gliomas.

Epigenetics 2015 21;10(6):496-507. Epub 2015 May 21.

a Department of Pathology & Cell Biology; Columbia University Medical Center ; New York , NY , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15592294.2015.1042645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622924PMC
March 2016

Regional and stage-specific effects of prospectively purified vascular cells on the adult V-SVZ neural stem cell lineage.

J Neurosci 2015 Mar;35(11):4528-39

Department of Neuroscience, Department of Pathology and Cell Biology, Department of Neurology, Department of Rehabilitation and Regenerative Medicine, and Columbia Stem Cell Initiative, Columbia University, College of Physicians and Surgeons, New York, New York 10032, and Biozentrum, University of Basel, Basel CH-4056, Switzerland

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1523/JNEUROSCI.1188-14.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363382PMC
March 2015

Stem cells in the nervous system.

Am J Phys Med Rehabil 2014 Nov;93(11 Suppl 3):S132-44

From the Columbia Stem Cell Initiative (ARM-S, DHO, HW, JS, FKD, CEH); Departments of Pathology and Cell Biology, Neurology and Neuroscience, Center for Motor Neuron Biology and Disease (ARM-S, DHO, HW, FKD, CEH); Project A.L.S./Jenifer Estess Laboratory for Stem Cell Research (DHO, HW, CEH); and Department of Rehabilitation and Regenerative Medicine (ARM-S, JS, FKD, CEH), Columbia University Medical Center, New York, New York.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PHM.0000000000000111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197112PMC
November 2014

A new twist for neurotrophins: endothelial-derived NT-3 mediates adult neural stem cell quiescence.

Neuron 2014 Aug;83(3):507-9

Department of Pathology & Cell Biology, Neuroscience, Neurology, and Rehabilitation & Regenerative Medicine, Columbia Stem Cell Initiative, Columbia University, 630 West 168(th) Street, New York, NY 10032, USA; Biozentrum, University of Basel, Klingelbergstrasse 50/70, CH-4056 Basel, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuron.2014.07.029DOI Listing
August 2014

Prospective identification and purification of quiescent adult neural stem cells from their in vivo niche.

Neuron 2014 May;82(3):545-59

Department of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA; Department of Neurology, Columbia University, New York, NY 10032, USA; Department of Neuroscience, Columbia University, New York, NY 10032, USA; Department of Rehabilitation and Regenerative Medicine, Columbia University, New York, NY 10032, USA; Columbia Stem Cell Initiative, Columbia University, New York, NY 10032, USA; Motor Neuron Center, Columbia University, New York, NY 10032, USA; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuron.2014.02.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360885PMC
May 2014

Adult neural stem cells and their niche: a dynamic duo during homeostasis, regeneration, and aging.

Curr Opin Neurobiol 2013 Dec 1;23(6):935-42. Epub 2013 Oct 1.

Department of Pathology and Cell Biology, Columbia University, College of Physicians and Surgeons, 630 West 168th Street, NYC, NY 10032, United States; Columbia Stem Cell Initiative, Columbia University, College of Physicians and Surgeons, 630 West 168th Street, NYC, NY 10032, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.conb.2013.09.004DOI Listing
December 2013

Eyes wide open: a critical review of sphere-formation as an assay for stem cells.

Cell Stem Cell 2011 May;8(5):486-98

Departments of Pathology and Cell Biology, Neurology, and Neuroscience, Columbia Stem Cell Initiative, Center for Motor Neuron Biology and Disease, Columbia University Medical Center, New York, NY 10032, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2011.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633588PMC
May 2011

The subventricular zone en-face: wholemount staining and ependymal flow.

J Vis Exp 2010 May 6(39). Epub 2010 May 6.

Department of Neurosurgery, The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco - UCSF.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3791/1938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144601PMC
May 2010

miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche.

Nat Neurosci 2009 Apr 15;12(4):399-408. Epub 2009 Mar 15.

Department of Pathology, Columbia University, College of Physicians and Surgeons, New York, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nn.2294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766245PMC
April 2009

Simultaneous prospective purification of adult subventricular zone neural stem cells and their progeny.

Proc Natl Acad Sci U S A 2009 Apr 30;106(15):6387-92. Epub 2009 Mar 30.

Department of Pathology and Cell Biology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

View Article

Download full-text PDF

Source
http://www.pnas.org/cgi/doi/10.1073/pnas.0810407106
Publisher Site
http://dx.doi.org/10.1073/pnas.0810407106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669396PMC
April 2009

Brain micro-ecologies: neural stem cell niches in the adult mammalian brain.

Philos Trans R Soc Lond B Biol Sci 2008 Jan;363(1489):123-37

Center for Neurobiology and Behavior, Columbia University, 630 West 168th Street, New York City, NY 10032, USA.

View Article

Download full-text PDF

Source
http://rstb.royalsocietypublishing.org/cgi/doi/10.1098/rstb.
Publisher Site
http://dx.doi.org/10.1098/rstb.2006.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605490PMC
January 2008

Zfx controls the self-renewal of embryonic and hematopoietic stem cells.

Cell 2007 Apr;129(2):345-57

Department of Microbiology, Columbia University Medical Center, New York, NY 10032, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2007.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899089PMC
April 2007

Stem cells: from epigenetics to microRNAs.

Neuron 2005 May;46(3):363-7

Department of Pathology, Columbia University, 630 West 168th Street, New York, New York 10032, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuron.2005.04.027DOI Listing
May 2005

Young and excitable: the function of new neurons in the adult mammalian brain.

Curr Opin Neurobiol 2005 Feb;15(1):121-8

Departments of Pathology, Neurology and Center for Neurobiology and Behavior, Columbia University, 630W 168th Street, NY, NY 10032, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S095943880500019
Publisher Site
http://dx.doi.org/10.1016/j.conb.2005.01.018DOI Listing
February 2005

The glial identity of neural stem cells.

Authors:
Fiona Doetsch

Nat Neurosci 2003 Nov 28;6(11):1127-34. Epub 2003 Oct 28.

Department of Molecular and Cellular Biology, Harvard University, 16 Divinity Avenue, Cambridge, Massachusetts 02138, USA.

View Article

Download full-text PDF

Source
http://www.bio.brandeis.edu/classes/nbio143/Papers/Stem%20ce
Web Search
http://www.nature.com/doifinder/10.1038/nn1144
Publisher Site
http://dx.doi.org/10.1038/nn1144DOI Listing
November 2003

A niche for adult neural stem cells.

Authors:
Fiona Doetsch

Curr Opin Genet Dev 2003 Oct;13(5):543-50

Harvard University, Department of Molecular and Cellular Biology, 16 Divinity Avenue, Cambridge, Massachusetts 02138, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gde.2003.08.012DOI Listing
October 2003

EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cells.

Neuron 2002 Dec;36(6):1021-34

Department of Molecular and Cellular Biology, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0896-6273(02)01133-9DOI Listing
December 2002

Genetics of childhood disorders: XXXVIII. Stem cell research, part 2: reconstructing the brain.

Authors:
Fiona Doetsch

J Am Acad Child Adolesc Psychiatry 2002 May;41(5):622-4

Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/00004583-200205000-00021DOI Listing
May 2002

Identification of neural stem cells in the adult vertebrate brain.

Brain Res Bull 2002 Apr;57(6):751-8

Department of Neurosurgery Research, Brain Tumor Research Center, University of California, San Francisco, CA, 94143 USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0361-9230(01)00770-5DOI Listing
April 2002