Fiona Cunningham

Fiona Cunningham

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Fiona Cunningham

Fiona Cunningham

Publications by authors named "Fiona Cunningham"

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Molecular mechanism of TMEM16A regulation: role of CaMKII and PP1/PP2A.

Am J Physiol Cell Physiol 2019 Dec 28;317(6):C1093-C1106. Epub 2019 Aug 28.

Department of Pharmacology, Center of Biomedical Research Excellence for Molecular and Cellular Signal Transduction in the Cardiovascular System, University of Nevada, Reno School of Medicine, Reno, Nevada.

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http://dx.doi.org/10.1152/ajpcell.00059.2018DOI Listing
December 2019

Correction: IQSEC2-related encephalopathy in males and females: a comparative study including 37 novel patients.

Genet Med 2019 Aug;21(8):1897-1898

INSERM, U 1127, CNRS UMR 7225, Sorbonne Universites, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle epiniere, ICM, Paris, France.

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http://dx.doi.org/10.1038/s41436-018-0327-7DOI Listing
August 2019

The Placental Growth Factor Pathway and Its Potential Role in Macular Degenerative Disease.

Curr Eye Res 2019 Aug 24;44(8):813-822. Epub 2019 May 24.

a Centre for Experimental Medicine, Queen's University Belfast , Belfast , Northern Ireland.

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https://www.tandfonline.com/doi/full/10.1080/02713683.2019.1
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http://dx.doi.org/10.1080/02713683.2019.1614197DOI Listing
August 2019

IQSEC2-related encephalopathy in males and females: a comparative study including 37 novel patients.

Genet Med 2019 04 12;21(4):837-849. Epub 2018 Sep 12.

INSERM, U 1127, CNRS UMR 7225, Sorbonne Universites, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle epiniere, ICM, Paris, France.

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http://dx.doi.org/10.1038/s41436-018-0268-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752297PMC
April 2019

The role of placental growth factor (PlGF) and its receptor system in retinal vascular diseases.

Prog Retin Eye Res 2019 03 30;69:116-136. Epub 2018 Oct 30.

Centre for Experimental Medicine, Queen's University Belfast, Northern Ireland, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S13509462183006
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http://dx.doi.org/10.1016/j.preteyeres.2018.10.006DOI Listing
March 2019

Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02.

Nat Commun 2019 03 8;10(1):1150. Epub 2019 Mar 8.

St. John's Institute of Dermatology, King's College London, London, Guy's Hospital, London, SE1 9RT, UK.

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http://dx.doi.org/10.1038/s41467-019-09117-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408457PMC
March 2019

Scaling up data curation using deep learning: An application to literature triage in genomic variation resources.

PLoS Comput Biol 2018 08 13;14(8):e1006390. Epub 2018 Aug 13.

National Center for Biotechnology Information (NCBI), National Library of Medicine (NLM), National Institutes of Health (NIH), Bethesda, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1006390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107285PMC
August 2018

Retrospective review of 18 British South Asian women with frontal fibrosing alopecia.

Int J Dermatol 2018 04 31;57(4):490-491. Epub 2018 Jan 31.

Solihull Hospital, Heart of England NHS Foundation Trust, Solihull, UK.

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http://dx.doi.org/10.1111/ijd.13929DOI Listing
April 2018

The Skin Surgery Patient Experience, a Retrospective Review.

Dermatol Surg 2018 Feb;44(2):308-310

Alan Lyell Centre for Dermatology, Queen Elizabeth University Hospital, Glasgow, United Kingdom.

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http://dx.doi.org/10.1097/DSS.0000000000001296DOI Listing
February 2018

Ensembl variation resources.

Database (Oxford) 2018 01 1;2018. Epub 2018 Jan 1.

European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.

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http://fdslive.oup.com/www.oup.com/pdf/production_in_progres
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http://dx.doi.org/10.1093/database/bay119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310513PMC
January 2018

Comment on standardized laboratory monitoring with use of isotretinoin in acne.

J Am Acad Dermatol 2017 04;76(4):e133

Alan Lyell Centre for Dermatology, Queen Elizabeth University Hospital, Glasgow, United Kingdom.

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http://dx.doi.org/10.1016/j.jaad.2016.10.047DOI Listing
April 2017

The Ensembl Variant Effect Predictor.

Genome Biol 2016 06 6;17(1):122. Epub 2016 Jun 6.

European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.

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http://dx.doi.org/10.1186/s13059-016-0974-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893825PMC
June 2016

Improving the Sequence Ontology terminology for genomic variant annotation.

J Biomed Semantics 2015 31;6:32. Epub 2015 Jul 31.

Department of Biomedical Informatics, University of Utah, Salt Lake City, UT USA.

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http://dx.doi.org/10.1186/s13326-015-0030-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520272PMC
August 2015

Application of a modified gaseous exposure system to the in vitro toxicological assessment of tobacco smoke toxicants.

Environ Mol Mutagen 2014 Oct 2;55(8):662-72. Epub 2014 Jun 2.

British American Tobacco, Group R&D, Southampton, Hampshire, SO15 8TL, United Kingdom.

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http://doi.wiley.com/10.1002/em.21876
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http://dx.doi.org/10.1002/em.21876DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710645PMC
October 2014

Respiratory physicians and clinic coordinators' attitudes to population-based cystic fibrosis carrier screening.

J Cyst Fibros 2014 Jan 25;13(1):99-105. Epub 2013 Jul 25.

Department of Paediatrics, University of Melbourne, Melbourne, 3052, Australia; Murdoch Children's Research Institute, Melbourne, 3052, Australia; Department of Respiratory Medicine, Royal Children's Hospital, Melbourne, 3052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jcf.2013.06.009DOI Listing
January 2014

Locus Reference Genomic: reference sequences for the reporting of clinically relevant sequence variants.

Nucleic Acids Res 2014 Jan 26;42(Database issue):D873-8. Epub 2013 Nov 26.

European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK, National Center for Biotechnology Information, Bethesda, MD 20894, USA, and Department of Genetics, University of Leicester, Leicester LE1 7RH, UK.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkt1198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965024PMC
January 2014

Policy challenges of clinical genome sequencing.

BMJ 2013 Nov 22;347:f6845. Epub 2013 Nov 22.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

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http://dx.doi.org/10.1136/bmj.f6845DOI Listing
November 2013

Acrylamide concentration determines the direction and magnitude of helical membrane protein gel shifts.

Proc Natl Acad Sci U S A 2013 Sep 9;110(39):15668-73. Epub 2013 Sep 9.

Division of Molecular Structure and Function, Research Institute, Hospital for Sick Children, Toronto, ON, Canada M5G 1X8.

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http://dx.doi.org/10.1073/pnas.1311305110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785759PMC
September 2013

Paralogous annotation of disease-causing variants in long QT syndrome genes.

Hum Mutat 2012 Aug 7;33(8):1188-1191. Epub 2012 Jun 7.

Medical Research Council Clinical Sciences Centre, Imperial College London, London W12 0NN, United Kingdom.

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http://dx.doi.org/10.1002/humu.22114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640174PMC
August 2012

Modulation of equine neutrophil adherence and migration by the annexin-1 derived N-terminal peptide, Ac2-26.

Vet Immunol Immunopathol 2012 Jan 19;145(1-2):214-22. Epub 2011 Nov 19.

Department of Veterinary Basic Sciences, Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire, AL9 7TA, UK.

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http://dx.doi.org/10.1016/j.vetimm.2011.11.011DOI Listing
January 2012

Modulation of substrate efflux in bacterial small multidrug resistance proteins by mutations at the dimer interface.

J Bacteriol 2011 Nov 2;193(21):5929-35. Epub 2011 Sep 2.

Division of Molecular Structure & Function, Research Institute, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8.

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http://dx.doi.org/10.1128/JB.05846-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194897PMC
November 2011

Beta-branched residues adjacent to GG4 motifs promote the efficient association of glycophorin A transmembrane helices.

Biopolymers 2011 ;96(3):340-7

Division of Molecular Structure and Function, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8.

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http://dx.doi.org/10.1002/bip.21565DOI Listing
September 2011

Converting a marginally hydrophobic soluble protein into a membrane protein.

J Mol Biol 2011 Mar 22;407(1):171-9. Epub 2011 Jan 22.

Department of Biochemistry and Biophysics, Center for Biomembrane Research, Stockholm University, SE-106 91 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jmb.2011.01.035DOI Listing
March 2011

CXCL8 attenuates chemoattractant-induced equine neutrophil migration.

Vet Immunol Immunopathol 2011 Feb 7;139(2-4):141-7. Epub 2010 Oct 7.

Department of Veterinary Basic Sciences, Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire, AL9 7TA, UK.

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http://dx.doi.org/10.1016/j.vetimm.2010.09.008DOI Listing
February 2011

From Materia Medica to veterinary pharmacology and therapeutics. Introduction.

Handb Exp Pharmacol 2010 (199):3-17

Department of Veterinary Basic Sciences, Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire AL97TA, UK.

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http://dx.doi.org/10.1007/978-3-642-10324-7_1DOI Listing
August 2010

Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor.

Bioinformatics 2010 Aug 18;26(16):2069-70. Epub 2010 Jun 18.

European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btq330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916720PMC
August 2010

Expression of annexin-1 in equine leucocytes and the effects of the N-terminal annexin-1 peptide, Ac2-26, on equine neutrophil superoxide production.

Vet Immunol Immunopathol 2010 Jun 16;135(3-4):226-33. Epub 2009 Dec 16.

Department of Veterinary Basic Sciences, The Royal Veterinary College, Hawkshead Campus, Hawkshead Lane, North Mymms, Hertfordshire AL9 7TA, UK.

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http://dx.doi.org/10.1016/j.vetimm.2009.12.002DOI Listing
June 2010

Evaluation of the effect of phosphodiesterase on equine platelet activation and the effect of antigen challenge on platelet phosphodiesterase activity in horses with recurrent airway obstruction.

Am J Vet Res 2010 May;71(5):534-40

Department of Veterinary Clinical Sciences, The Royal Veterinary College, North Mymms, Herts AL9 7TA, England.

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http://dx.doi.org/10.2460/ajvr.71.5.534DOI Listing
May 2010

Ensembl variation resources.

BMC Genomics 2010 May 11;11:293. Epub 2010 May 11.

European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.

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http://dx.doi.org/10.1186/1471-2164-11-293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894800PMC
May 2010

A database and API for variation, dense genotyping and resequencing data.

BMC Bioinformatics 2010 May 11;11:238. Epub 2010 May 11.

European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.

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http://dx.doi.org/10.1186/1471-2105-11-238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882931PMC
May 2010

Endotoxin-induced activation of equine digital vein endothelial cells: role of p38 MAPK.

Vet Immunol Immunopathol 2009 Jun 7;129(3-4):174-80. Epub 2008 Nov 7.

Department of Veterinary Basic Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire AL9 7TA, UK.

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http://dx.doi.org/10.1016/j.vetimm.2008.11.008DOI Listing
June 2009

Hydrophobic peptide segments in soluble proteins competent for membrane insertion: role in amyloidogenesis.

Adv Exp Med Biol 2009 ;611:299-300

Division of Molecular Structure & Function, Research Institute, Hospital for Sick Children, Toronto M5G 1X8, Canada.

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http://dx.doi.org/10.1007/978-0-387-73657-0_134DOI Listing
June 2009

Distinctions between hydrophobic helices in globular proteins and transmembrane segments as factors in protein sorting.

J Biol Chem 2009 Feb 18;284(8):5395-402. Epub 2008 Dec 18.

Division of Molecular Structure and Function, Research Institute, Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada.

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http://dx.doi.org/10.1074/jbc.M809017200DOI Listing
February 2009

Equine recurrent airway obstruction and insect bite hypersensitivity: understanding the diseases and uncovering possible new therapeutic approaches.

Vet J 2008 Sep 19;177(3):334-44. Epub 2007 Nov 19.

Department of Veterinary Basic Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire AL9 7TA, UK.

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http://dx.doi.org/10.1016/j.tvjl.2007.10.005DOI Listing
September 2008

Roles of thromboxane A2 and 5-hydroxytryptamine in endotoxin-induced digital vasoconstriction in horses.

Am J Vet Res 2008 Feb;69(2):199-207

Department of Veterinary Clinical Sciences, Royal Veterinary College, Hatfield, Hertfordshire AL9 7TA, England.

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http://dx.doi.org/10.2460/ajvr.69.2.199DOI Listing
February 2008

Phosphodiesterase isoenzymes in equine platelets and their influence on platelet adhesion.

Am J Vet Res 2007 Dec;68(12):1354-60

Department of Veterinary Basic Sciences, The Royal Veterinary College, North Mymms, Herts, England.

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http://dx.doi.org/10.2460/ajvr.68.12.1354DOI Listing
December 2007

Optimizing synthesis and expression of transmembrane peptides and proteins.

Methods 2007 Apr;41(4):370-80

Division of Structural Biology and Biochemistry, Research Institute, Hospital for Sick Children, Toronto, Department of Biochemistry, University of Toronto, Toronto, Ont., Canada.

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http://dx.doi.org/10.1016/j.ymeth.2006.07.003DOI Listing
April 2007

Distribution of CCR3 mRNA expression in horse tissues.

Vet Immunol Immunopathol 2006 Dec 18;114(3-4):238-46. Epub 2006 Sep 18.

Department of Veterinary Basic Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire AL9 7TA, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S016524270600235
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http://dx.doi.org/10.1016/j.vetimm.2006.08.010DOI Listing
December 2006

Characterisation of the biological activity of recombinant equine eotaxin in vitro.

Cytokine 2002 Jul;19(1):27-30

Department of Pathology and Infectious Diseases, The Royal Veterinary College, University of London, Hawkshead Campus, Hertfordshire, AL9 7TA, UK.

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http://dx.doi.org/10.1006/cyto.2002.1052DOI Listing
July 2002