Finn Sellebjerg

Finn Sellebjerg

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Finn Sellebjerg

Publications by authors named "Finn Sellebjerg"

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Prognostic value of cerebrospinal fluid neurofilament light chain and chitinase-3-like-1 in newly diagnosed patients with multiple sclerosis.

Mult Scler 2019 Oct 16;25(11):1444-1451. Epub 2018 Aug 16.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458518794308DOI Listing
October 2019

Dimethyl fumarate therapy suppresses B cell responses and follicular helper T cells in relapsing-remitting multiple sclerosis.

Mult Scler 2019 Aug 25;25(9):1289-1297. Epub 2018 Jul 25.

The Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458518790417DOI Listing
August 2019

Smoking is associated with increased disease activity during natalizumab treatment in multiple sclerosis.

Mult Scler 2019 Aug 2;25(9):1298-1305. Epub 2018 Aug 2.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458518791753DOI Listing
August 2019

The transcriptome of peripheral blood mononuclear cells in patients with clinical subtypes of late age-related macular degeneration.

Immun Ageing 2019 15;16:20. Epub 2019 Aug 15.

1Clinical Eye Research Division, Department of Ophthalmology, Zealand University Hospital, Vestermarksvej 23, DK-4000 Roskilde, Denmark.

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http://dx.doi.org/10.1186/s12979-019-0160-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696679PMC
August 2019

CSF inflammatory biomarkers responsive to treatment in progressive multiple sclerosis capture residual inflammation associated with axonal damage.

Mult Scler 2019 Jun 18;25(7):937-946. Epub 2018 May 18.

Department of Neurology, Danish Multiple Sclerosis Center, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458518774880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212343PMC
June 2019

Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis.

JAMA Neurol 2019 Jun 17. Epub 2019 Jun 17.

UCL Institute of Neurology, Queen Square, London, United Kingdom.

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http://dx.doi.org/10.1001/jamaneurol.2019.1534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580449PMC
June 2019

Relationship between Multiple Sclerosis-Associated Risk Allele Variants and Circulating T Cell Phenotypes in Healthy Genotype-Selected Controls.

Cells 2019 06 25;8(6). Epub 2019 Jun 25.

Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen University Hospital, Rigshospitalet, 2600 Glostrup, Denmark.

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http://dx.doi.org/10.3390/cells8060634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628508PMC
June 2019

Perfluorinated substances, risk factors for multiple sclerosis and cellular immune activation.

J Neuroimmunol 2019 May 2;330:90-95. Epub 2019 Mar 2.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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https://linkinghub.elsevier.com/retrieve/pii/S01655728193000
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http://dx.doi.org/10.1016/j.jneuroim.2019.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461219PMC
May 2019

Functional neuroimaging of recovery from motor conversion disorder: A case report.

Neuroimage 2019 04 27;190:269-274. Epub 2018 Mar 27.

Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Kettegard Allé 30, 2650 Hvidovre, Denmark; Department of Neurology, Copenhagen University Hospital Bispebjerg, Bispebjerg Bakke 23, 2400 Copenhagen, NV, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2018.03.061DOI Listing
April 2019

Comparative effectiveness of teriflunomide and dimethyl fumarate: A nationwide cohort study.

Neurology 2019 Apr 15;92(16):e1811-e1820. Epub 2019 Mar 15.

From the Danish Multiple Sclerosis Center (M.D.B., T.A.C., F.S., P.S.S., M.M.), Rigshospitalet; Copenhagen University Hospital Rigshospitalet (J.F., H.H.-K.-R.), Glostrup; Slagelse Hospital (M.K.G.); Odense University Hospital (Z.I., T.S.), University of Southern Denmark; Hospital of Southern Jutland (M.K.), Sønderborg; Aalborg University Hospital (Z.M.); Aarhus University Hospital (T.P., P.V.R.); Greater Copenhagen Hospitals-NOH (H.R.), Hillerød; University Hospital of Sjaelland (A.T.), Roskilde; and Department of Neurology, Copenhagen University Hospital Herlev (A.W.), Denmark.

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http://dx.doi.org/10.1212/WNL.0000000000007314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550503PMC
April 2019

Prediction of natalizumab anti-drug antibodies persistency.

Mult Scler 2019 03 16;25(3):392-398. Epub 2018 Jan 16.

Centre de Physiopathologie Toulouse-Purpan, INSERM UMR-1043, CNRS UMR 5282, Université Toulouse III, Toulouse, France.

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http://dx.doi.org/10.1177/1352458517753721DOI Listing
March 2019

IL-6, IL-12, and IL-23 STAT-Pathway Genetic Risk and Responsiveness of Lymphocytes in Patients with Multiple Sclerosis.

Cells 2019 03 26;8(3). Epub 2019 Mar 26.

The Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100 Copenhagen, Denmark.

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http://dx.doi.org/10.3390/cells8030285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468786PMC
March 2019

Pulsed immune reconstitution therapy in multiple sclerosis.

Ther Adv Neurol Disord 2019 28;12:1756286419836913. Epub 2019 Mar 28.

Department of Neurology, Danish Multiple Sclerosis Center, University of Copenhagen, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1756286419836913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440030PMC
March 2019

GPR15 T cells are Th17 like, increased in smokers and associated with multiple sclerosis.

J Autoimmun 2019 Feb 21;97:114-121. Epub 2018 Sep 21.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, DK-2100, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2018.09.005DOI Listing
February 2019

Structural and cognitive correlates of fatigue in progressive multiple sclerosis.

Neurol Res 2019 Feb 4;41(2):168-176. Epub 2018 Dec 4.

a Danish Multiple Sclerosis Centre (DMSC), Department of Neurology , Rigshospitalet, University of Copenhagen , Copenhagen , Denmark.

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http://dx.doi.org/10.1080/01616412.2018.1547813DOI Listing
February 2019

Proinflammatory CD20+ T cells in the pathogenesis of multiple sclerosis.

Brain 2019 01;142(1):120-132

The Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, Copenhagen, Denmark.

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http://dx.doi.org/10.1093/brain/awy301DOI Listing
January 2019

Nationwide prevalence and incidence study of neuromyelitis optica spectrum disorder in Denmark.

Neurology 2018 12 9;91(24):e2265-e2275. Epub 2018 Nov 9.

From the Department of Neurology (V.P., K.S., T.P.), Aarhus University Hospital; Department of Neurology (Z.I., H.H.N.), Odense University Hospital; Institute of Clinical Research (Z.I., H.H.N.), Institute of Molecular Biology (H.H.N.), and Department of Regional Health Research, Faculty of Health Sciences (E.S.), University of Southern Denmark, Odense; The Danish Multiple Sclerosis Center (M.M., P.E.H.J., F.S.), Department of Neurology, Rigshospitalet, University of Copenhagen; The Danish Multiple Sclerosis Registry (M.M., N.K.-H.), Department of Neurology, Rigshospitalet, Copenhagen University Hospital; Department of Clinical Epidemiology, Clinical Institute (N.K.-H.), and Department of Biomedicine (T.C.), Aarhus University; MS-Clinic of Southern Jutland (Sønderborg, Esbjerg, Kolding) (M.K., E.S.), Department of Neurology, Hospital of Southern Jutland, Sønderborg; Department of Neurology (C.C.P., Z.M.), Aalborg University Hospital; Multiple Sclerosis Unit (S.F.R.), Department of Neurology, Herlev Hospital, Copenhagen; Department of Neurology (M.B.J.), Nordsjællands Hospital, Hillerød; Department of Neurology (A.E.P.), Hospital of Southwest Jutland, Esbjerg; Department of Neurology (L.R.), Hospital of Central Denmark Region, Viborg; Department of Autoimmunology and Biomarkers (M.C.L., N.H.), Statens Serum Institut, Copenhagen; and Department of Neurology (J.L.F.), Rigshospitalet Glostrup, Faculty of Health and Medical Sciences, University of Copenhagen, Glostrup, Denmark.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000006645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329324PMC
December 2018

Inflammatory markers of CHMP2B-mediated frontotemporal dementia.

J Neuroimmunol 2018 Nov 17;324:136-142. Epub 2018 Aug 17.

Danish Dementia Research Centre, Department of Neurology, Rigshospitalet, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.jneuroim.2018.08.009DOI Listing
November 2018

Clinical utility of anti-MOG antibody testing in a Danish cohort.

Mult Scler Relat Disord 2018 Nov 11;26:61-67. Epub 2018 Sep 11.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, Copenhagen 2100, Denmark.

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http://dx.doi.org/10.1016/j.msard.2018.09.010DOI Listing
November 2018

B cells from patients with multiple sclerosis have a pathogenic phenotype and increased LTα and TGFβ1 response.

J Neuroimmunol 2018 Nov 7;324:157-164. Epub 2018 Sep 7.

The Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.jneuroim.2018.09.001DOI Listing
November 2018

Increased cerebrospinal fluid chitinase 3-like 1 and neurofilament light chain in pediatric acquired demyelinating syndromes.

Mult Scler Relat Disord 2018 Aug 11;24:175-183. Epub 2018 Jun 11.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Denmark.

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http://dx.doi.org/10.1016/j.msard.2018.05.017DOI Listing
August 2018

Alcohol consumption in adolescence is associated with a lower risk of multiple sclerosis in a Danish cohort.

Mult Scler 2018 Aug 20:1352458518795418. Epub 2018 Aug 20.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458518795418DOI Listing
August 2018

Smoking affects the interferon beta treatment response in multiple sclerosis.

Neurology 2018 02 17;90(7):e593-e600. Epub 2018 Jan 17.

From the Danish Multiple Sclerosis Center (E.R.P., A.B.O., M.M., P.S.S., F.S., H.B.S.), Department of Neurology, and Danish Multiple Sclerosis Treatment Register (N.K.-H., M.M.), Rigshospitalet, University of Copenhagen; and Department of Clinical Epidemiology (N.K.-H), Clinical Institute, University of Aarhus, Denmark.

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http://dx.doi.org/10.1212/WNL.0000000000004949DOI Listing
February 2018

Progressive multiple sclerosis, cognitive function, and quality of life.

Brain Behav 2018 02 5;8(2):e00875. Epub 2018 Jan 5.

Department of Neurology Danish Multiple Sclerosis Center Rigshospitalet University of Copenhagen Copenhagen Denmark.

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http://dx.doi.org/10.1002/brb3.875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822575PMC
February 2018

Defining active progressive multiple sclerosis.

Mult Scler 2017 Nov 23;23(13):1727-1735. Epub 2017 Aug 23.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458517726592DOI Listing
November 2017

Characterization of naïve, memory and effector T cells in progressive multiple sclerosis.

J Neuroimmunol 2017 09 3;310:17-25. Epub 2017 Jun 3.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshopitalet, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.jneuroim.2017.06.001DOI Listing
September 2017

Smoking reduces circulating CD26CD161 MAIT cells in healthy individuals and patients with multiple sclerosis.

J Leukoc Biol 2017 05 8;101(5):1211-1220. Epub 2017 Feb 8.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1189/jlb.3A0616-267RDOI Listing
May 2017

Relationship between soluble CD25 and gene expression in healthy individuals and patients with multiple sclerosis.

Cytokine 2017 05 13;93:15-25. Epub 2017 May 13.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.cyto.2017.04.024DOI Listing
May 2017

High-dose erythropoietin in patients with progressive multiple sclerosis: A randomized, placebo-controlled, phase 2 trial.

Mult Scler 2017 Apr 5;23(5):675-685. Epub 2016 Aug 5.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458516661048DOI Listing
April 2017

Genetic burden of MS risk variants distinguish patients from healthy individuals but are not associated with disease activity.

Mult Scler Relat Disord 2017 Apr 31;13:25-27. Epub 2017 Jan 31.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.msard.2017.01.015DOI Listing
April 2017

A comparison of multiple sclerosis clinical disease activity between patients treated with natalizumab and fingolimod.

Mult Scler 2017 Feb 11;23(2):234-241. Epub 2016 Jul 11.

The Danish Multiple Sclerosis Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458516643393DOI Listing
February 2017

Selected CSF biomarkers indicate no evidence of early neuroinflammation in Huntington disease.

Neurol Neuroimmunol Neuroinflamm 2016 Dec 28;3(6):e287. Epub 2016 Sep 28.

Neurogenetics Clinic, Danish Dementia Research Centre (T.-V.J., I.U.L., L.E.H., J.E.N.), and Danish Multiple Sclerosis Center (L.B., C.A., F.S.), Department of Neurology, Rigshospitalet, Department of Cellular and Molecular Medicine, Section of Neurogenetics (T.-V.J., L.E.H., J.E.N.), Section of Biostatistics (E.B.-J.), and Department of Psychology (I.U.L.), University of Copenhagen, Denmark.

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http://dx.doi.org/10.1212/NXI.0000000000000287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042104PMC
December 2016

Vitamin D supplementation reduces relapse rate in relapsing-remitting multiple sclerosis patients treated with natalizumab.

Mult Scler Relat Disord 2016 Nov 26;10:169-173. Epub 2016 Oct 26.

Rigshospitalet, Copenhagen University Hospital, Danish Multiple Sclerosis Center, Department of Neurology, Blegdamsvej 9, 2100 Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.msard.2016.10.005DOI Listing
November 2016

Recovery from an acute relapse is associated with changes in motor resting-state connectivity in multiple sclerosis.

J Neurol Neurosurg Psychiatry 2016 08 14;87(8):912-4. Epub 2015 Dec 14.

Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital, Hvidovre, Denmark Cognitive Systems, Department of Applied Mathematics and Computer Science, Technical University of Denmark, Kgs. Lyngby, Denmark.

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http://dx.doi.org/10.1136/jnnp-2015-311375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975821PMC
August 2016

Neurofilament in CSF-A biomarker of disease activity and long-term prognosis in multiple sclerosis.

Mult Scler 2016 08 30;22(9):1112-3. Epub 2016 Jun 30.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458516658560DOI Listing
August 2016

Absence of systemic oxidative stress and increased CSF prostaglandin F2α in progressive MS.

Neurol Neuroimmunol Neuroinflamm 2016 Aug 30;3(4):e256. Epub 2016 Jun 30.

Vascular Biology Division (M.A.L., G.J.M., R.S.), Victor Chang Cardiac Research Institute, Sydney; School of Medical Sciences (G.J.M., R.S.), University of New South Wales, Sydney, Australia; Neuroimmunology Unit (M.K., F.P., T.O.), Department of Clinical Neurosciences, Centre for Molecular Medicine, Karolinska Hospital, Stockholm, Sweden; and Department of Neurology (R.R., J.R.C., F.T.S.), Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1212/NXI.0000000000000256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929888PMC
August 2016

Human pegivirus detected in a patient with severe encephalitis using a metagenomic pan-virus array.

J Clin Virol 2016 Apr 29;77:5-8. Epub 2016 Jan 29.

Virus Research and Development, Department of Microbiological Diagnostics and Virology, Statens Serum Institut, Copenhagen, Denmark; Infectious Disease Research Unit, Clinical Institute, University of Southern Denmark, Denmark.

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http://dx.doi.org/10.1016/j.jcv.2016.01.013DOI Listing
April 2016

Cytokine profiles show heterogeneity of interferon-β response in multiple sclerosis patients.

Neurol Neuroimmunol Neuroinflamm 2016 Apr 27;3(2):e202. Epub 2016 Jan 27.

Department of Neurology (H.H., A.M., M.H., D.R., F.D.), Medical University of Innsbruck, Austria; Department of Arthritis and Clinical Immunology (I.A., C.J.L., R.C.A.), Oklahoma Medical Research Foundation, Oklahoma City; Centro di Riferimento Regionale Sclerosi Multipla (A.B., S.N.), Neurologia 2, Azienda Ospedaliero Universitaria San Luigi Gonzaga, Orbassano, Turin, Italy; Centre d'Esclerosi Múltiple de Catalunya (Cemcat) (M.C., X.M.), Unitat de Neuroimmunologia Clínica, Hospital Universitari Vall d'Hebron, Barcelona, Spain; Queen Mary University London (G.G.), Blizard Institute, Barts and The London School of Medicine and Dentistry, London, UK; Clinical Department of Neurology (M.G.), Allgemeines Krankenhaus Linz, Austria; Department of Neurology (M.K., F.F.), Medical University of Graz, Austria; Department of Neurology (J.K.), Vrije Universiteit Medical Center, Amsterdam, the Netherlands; Department of Biomedicines and Neurology (R.L.P.L., M.M.), Clinical Neuroimmunology, University of Basel, University Hospital Basel, Switzerland; Clinical Department of Neurology (F. Schautzer), Landeskrankenhaus Villach, Austria; Danish Multiple Sclerosis Center (F. Sellebjerg, P.S.S.), Department of Neurology, Rigshospitalet, University of Copenhagen, Denmark; and Department of Neurology and Neurological Sciences (L.S.), Stanford University School of Medicine, CA.

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http://dx.doi.org/10.1212/NXI.0000000000000202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747480PMC
April 2016

Lipocalin-2 is increased in progressive multiple sclerosis and inhibits remyelination.

Neurol Neuroimmunol Neuroinflamm 2016 Feb 7;3(1):e191. Epub 2016 Jan 7.

Neuroimmunology Unit (F.A.N., M.K., S.A., T.O., F.P.), Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Institute of Infection, Immunity and Inflammation (C.E., C.L.), University of Glasgow, UK; Department of Pharmacology and Clinical Neuroscience (J.B., A.M.D., A.S.) and Neurosurgery (T.B.), Umeå University, Sweden; and Danish Multiple Sclerosis Center (J.R.C., F.S.), Department of Neurology, Rigshospitalet, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1212/NXI.0000000000000191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708925PMC
February 2016

Association between age at onset of multiple sclerosis and vitamin D level-related factors.

Neurology 2016 Jan 7;86(1):88-93. Epub 2015 Oct 7.

From Rigshospitalet, Copenhagen University Hospital, Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen, Denmark.

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http://dx.doi.org/10.1212/WNL.0000000000002075DOI Listing
January 2016

Genetic and environmental determinants of 25-hydroxyvitamin D levels in multiple sclerosis.

Mult Scler 2015 Oct 22;21(11):1414-22. Epub 2014 Dec 22.

Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Danish Multiple Sclerosis Center, Denmark.

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http://journals.sagepub.com/doi/10.1177/1352458514563590
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http://dx.doi.org/10.1177/1352458514563590DOI Listing
October 2015

Multiple sclerosis: A clinically useful genetic variant in multiple sclerosis?

Nat Rev Neurol 2015 Jul 16;11(7):371-2. Epub 2015 Jun 16.

Danish Multiple Sclerosis Centre, Department of Neurology, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100 Copenhagen, Denmark.

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http://dx.doi.org/10.1038/nrneurol.2015.103DOI Listing
July 2015

Recurrence or rebound of clinical relapses after discontinuation of natalizumab therapy in highly active MS patients.

J Neurol 2014 Jun 12;261(6):1170-7. Epub 2014 Apr 12.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark,

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http://link.springer.com/content/pdf/10.1007/s00415-014-7325
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http://link.springer.com/10.1007/s00415-014-7325-8
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http://dx.doi.org/10.1007/s00415-014-7325-8DOI Listing
June 2014

Natalizumab in progressive MS: results of an open-label, phase 2A, proof-of-concept trial.

Neurology 2014 Apr 28;82(17):1499-507. Epub 2014 Mar 28.

From the Danish Multiple Sclerosis Center (J.R.C., R.R., L.B., P.S.S., F.S.), Department of Neurology, Copenhagen University Hospital, Rigshospitalet, Copenhagen; Danish Research Center for Magnetic Resonance (M.L., E.G., T.B.D., H.R.S.), Copenhagen University Hospital Hvidovre, Denmark.

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http://dx.doi.org/10.1212/WNL.0000000000000361DOI Listing
April 2014

Onset symptoms in paediatric multiple sclerosis.

Dan Med J 2014 Apr;61(4):A4800

Dansk Multipel Sclerose Center, Neurologisk Klinik N2082, Rigshospitalet, 2100 Copenhagen, Denmark.

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April 2014

Clinical relevance of brain volume measures in multiple sclerosis.

CNS Drugs 2014 Feb;28(2):147-56

Department of Medicine, Surgery and Neuroscience, University of Siena, Viale Bracci 2, Siena, 53100, Italy,

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http://link.springer.com/10.1007/s40263-014-0140-z
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http://dx.doi.org/10.1007/s40263-014-0140-zDOI Listing
February 2014

Differential microRNA expression in blood in multiple sclerosis.

Mult Scler 2013 Dec 17;19(14):1849-57. Epub 2013 Jun 17.

Department of Neurology, Copenhagen University Hospital Rigshospitalet, Denmark.

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http://dx.doi.org/10.1177/1352458513490542DOI Listing
December 2013

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.

Authors:
Ashley H Beecham Nikolaos A Patsopoulos Dionysia K Xifara Mary F Davis Anu Kemppinen Chris Cotsapas Tejas S Shah Chris Spencer David Booth An Goris Annette Oturai Janna Saarela Bertrand Fontaine Bernhard Hemmer Claes Martin Frauke Zipp Sandra D'Alfonso Filippo Martinelli-Boneschi Bruce Taylor Hanne F Harbo Ingrid Kockum Jan Hillert Tomas Olsson Maria Ban Jorge R Oksenberg Rogier Hintzen Lisa F Barcellos Cristina Agliardi Lars Alfredsson Mehdi Alizadeh Carl Anderson Robert Andrews Helle Bach Søndergaard Amie Baker Gavin Band Sergio E Baranzini Nadia Barizzone Jeffrey Barrett Céline Bellenguez Laura Bergamaschi Luisa Bernardinelli Achim Berthele Viola Biberacher Thomas M C Binder Hannah Blackburn Izaura L Bomfim Paola Brambilla Simon Broadley Bruno Brochet Lou Brundin Dorothea Buck Helmut Butzkueven Stacy J Caillier William Camu Wassila Carpentier Paola Cavalla Elisabeth G Celius Irène Coman Giancarlo Comi Lucia Corrado Leentje Cosemans Isabelle Cournu-Rebeix Bruce A C Cree Daniele Cusi Vincent Damotte Gilles Defer Silvia R Delgado Panos Deloukas Alessia di Sapio Alexander T Dilthey Peter Donnelly Bénédicte Dubois Martin Duddy Sarah Edkins Irina Elovaara Federica Esposito Nikos Evangelou Barnaby Fiddes Judith Field Andre Franke Colin Freeman Irene Y Frohlich Daniela Galimberti Christian Gieger Pierre-Antoine Gourraud Christiane Graetz Andrew Graham Verena Grummel Clara Guaschino Athena Hadjixenofontos Hakon Hakonarson Christopher Halfpenny Gillian Hall Per Hall Anders Hamsten James Harley Timothy Harrower Clive Hawkins Garrett Hellenthal Charles Hillier Jeremy Hobart Muni Hoshi Sarah E Hunt Maja Jagodic Ilijas Jelčić Angela Jochim Brian Kendall Allan Kermode Trevor Kilpatrick Keijo Koivisto Ioanna Konidari Thomas Korn Helena Kronsbein Cordelia Langford Malin Larsson Mark Lathrop Christine Lebrun-Frenay Jeannette Lechner-Scott Michelle H Lee Maurizio A Leone Virpi Leppä Giuseppe Liberatore Benedicte A Lie Christina M Lill Magdalena Lindén Jenny Link Felix Luessi Jan Lycke Fabio Macciardi Satu Männistö Clara P Manrique Roland Martin Vittorio Martinelli Deborah Mason Gordon Mazibrada Cristin McCabe Inger-Lise Mero Julia Mescheriakova Loukas Moutsianas Kjell-Morten Myhr Guy Nagels Richard Nicholas Petra Nilsson Fredrik Piehl Matti Pirinen Siân E Price Hong Quach Mauri Reunanen Wim Robberecht Neil P Robertson Mariaemma Rodegher David Rog Marco Salvetti Nathalie C Schnetz-Boutaud Finn Sellebjerg Rebecca C Selter Catherine Schaefer Sandip Shaunak Ling Shen Simon Shields Volker Siffrin Mark Slee Per Soelberg Sorensen Melissa Sorosina Mireia Sospedra Anne Spurkland Amy Strange Emilie Sundqvist Vincent Thijs John Thorpe Anna Ticca Pentti Tienari Cornelia van Duijn Elizabeth M Visser Steve Vucic Helga Westerlind James S Wiley Alastair Wilkins James F Wilson Juliane Winkelmann John Zajicek Eva Zindler Jonathan L Haines Margaret A Pericak-Vance Adrian J Ivinson Graeme Stewart David Hafler Stephen L Hauser Alastair Compston Gil McVean Philip De Jager Stephen J Sawcer Jacob L McCauley

Nat Genet 2013 Nov 29;45(11):1353-60. Epub 2013 Sep 29.

1] John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA. [2].

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http://dx.doi.org/10.1038/ng.2770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832895PMC
November 2013

Clinically silent PML and prolonged immune reconstitution inflammatory syndrome in a patient with multiple sclerosis treated with natalizumab.

Mult Scler 2013 Aug 18;19(9):1226-9. Epub 2013 Mar 18.

Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen University Hospital, Rigshospitalet, Denmark.

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http://dx.doi.org/10.1177/1352458513481010DOI Listing
August 2013

CSF inflammation and axonal damage are increased and correlate in progressive multiple sclerosis.

Mult Scler 2013 Jun 24;19(7):877-84. Epub 2012 Nov 24.

University of Copenhagen and Department of Neurology, Copenhagen University Hospital Rigshospitalet, Denmark.

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http://journals.sagepub.com/doi/10.1177/1352458512466929
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http://dx.doi.org/10.1177/1352458512466929DOI Listing
June 2013

Effect of natalizumab on circulating CD4+ T-cells in multiple sclerosis.

PLoS One 2012 30;7(11):e47578. Epub 2012 Nov 30.

Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0047578PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511477PMC
May 2013

Preserved in vivo response to interferon-alpha in multiple sclerosis patients with neutralising antibodies against interferon-beta (REPAIR study).

Mult Scler Relat Disord 2013 Apr 11;2(2):141-6. Epub 2012 Dec 11.

Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.msard.2012.10.001DOI Listing
April 2013

Endogenous and recombinant type I interferons and disease activity in multiple sclerosis.

PLoS One 2012 6;7(6):e35927. Epub 2012 Jun 6.

Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035927PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368920PMC
November 2012

Prediction of antibody persistency from antibody titres to natalizumab.

Mult Scler 2012 Oct 27;18(10):1493-9. Epub 2012 Mar 27.

Danish Multiple Sclerosis Centre, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458512441688DOI Listing
October 2012

Cellular sources of dysregulated cytokines in relapsing-remitting multiple sclerosis.

J Neuroinflammation 2012 Sep 14;9:215. Epub 2012 Sep 14.

Department of Neurology, Danish Multiple Sclerosis Center, Copenhagen University Hospital Rigshospitalet, Blegdamsvej 9, Copenhagen, 2100, Denmark.

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http://dx.doi.org/10.1186/1742-2094-9-215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503813PMC
September 2012

[Anti-thyroid antibodies in two patients with subacute dementia, ataxia, and myoclonus].

Ugeskr Laeger 2012 Feb;174(9):577-9

Neurologisk Klinik, Afsnit 2094, Rigshospitalet, Blegdamsvej 9, 2100 København Ø, Denmark.

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February 2012

Interleukin-2 effect on T cell activation revealed by daclizumab treatment.

Authors:
Finn Sellebjerg

Mult Scler Relat Disord 2012 Jan 8;1(1). Epub 2011 Sep 8.

Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2011.08.004DOI Listing
January 2012

Variation in NOD2 augments Th2- and Th17 responses to myelin basic protein in multiple sclerosis.

PLoS One 2011 20;6(5):e20253. Epub 2011 May 20.

Institute for Inflammation Research, Department of Rheumatology, Copenhagen University Hospital, Rigshospitalet, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0020253PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098873PMC
October 2011

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

Authors:
Stephen Sawcer Garrett Hellenthal Matti Pirinen Chris C A Spencer Nikolaos A Patsopoulos Loukas Moutsianas Alexander Dilthey Zhan Su Colin Freeman Sarah E Hunt Sarah Edkins Emma Gray David R Booth Simon C Potter An Goris Gavin Band Annette Bang Oturai Amy Strange Janna Saarela Céline Bellenguez Bertrand Fontaine Matthew Gillman Bernhard Hemmer Rhian Gwilliam Frauke Zipp Alagurevathi Jayakumar Roland Martin Stephen Leslie Stanley Hawkins Eleni Giannoulatou Sandra D'alfonso Hannah Blackburn Filippo Martinelli Boneschi Jennifer Liddle Hanne F Harbo Marc L Perez Anne Spurkland Matthew J Waller Marcin P Mycko Michelle Ricketts Manuel Comabella Naomi Hammond Ingrid Kockum Owen T McCann Maria Ban Pamela Whittaker Anu Kemppinen Paul Weston Clive Hawkins Sara Widaa John Zajicek Serge Dronov Neil Robertson Suzannah J Bumpstead Lisa F Barcellos Rathi Ravindrarajah Roby Abraham Lars Alfredsson Kristin Ardlie Cristin Aubin Amie Baker Katharine Baker Sergio E Baranzini Laura Bergamaschi Roberto Bergamaschi Allan Bernstein Achim Berthele Mike Boggild Jonathan P Bradfield David Brassat Simon A Broadley Dorothea Buck Helmut Butzkueven Ruggero Capra William M Carroll Paola Cavalla Elisabeth G Celius Sabine Cepok Rosetta Chiavacci Françoise Clerget-Darpoux Katleen Clysters Giancarlo Comi Mark Cossburn Isabelle Cournu-Rebeix Mathew B Cox Wendy Cozen Bruce A C Cree Anne H Cross Daniele Cusi Mark J Daly Emma Davis Paul I W de Bakker Marc Debouverie Marie Beatrice D'hooghe Katherine Dixon Rita Dobosi Bénédicte Dubois David Ellinghaus Irina Elovaara Federica Esposito Claire Fontenille Simon Foote Andre Franke Daniela Galimberti Angelo Ghezzi Joseph Glessner Refujia Gomez Olivier Gout Colin Graham Struan F A Grant Franca Rosa Guerini Hakon Hakonarson Per Hall Anders Hamsten Hans-Peter Hartung Rob N Heard Simon Heath Jeremy Hobart Muna Hoshi Carmen Infante-Duarte Gillian Ingram Wendy Ingram Talat Islam Maja Jagodic Michael Kabesch Allan G Kermode Trevor J Kilpatrick Cecilia Kim Norman Klopp Keijo Koivisto Malin Larsson Mark Lathrop Jeannette S Lechner-Scott Maurizio A Leone Virpi Leppä Ulrika Liljedahl Izaura Lima Bomfim Robin R Lincoln Jenny Link Jianjun Liu Aslaug R Lorentzen Sara Lupoli Fabio Macciardi Thomas Mack Mark Marriott Vittorio Martinelli Deborah Mason Jacob L McCauley Frank Mentch Inger-Lise Mero Tania Mihalova Xavier Montalban John Mottershead Kjell-Morten Myhr Paola Naldi William Ollier Alison Page Aarno Palotie Jean Pelletier Laura Piccio Trevor Pickersgill Fredrik Piehl Susan Pobywajlo Hong L Quach Patricia P Ramsay Mauri Reunanen Richard Reynolds John D Rioux Mariaemma Rodegher Sabine Roesner Justin P Rubio Ina-Maria Rückert Marco Salvetti Erika Salvi Adam Santaniello Catherine A Schaefer Stefan Schreiber Christian Schulze Rodney J Scott Finn Sellebjerg Krzysztof W Selmaj David Sexton Ling Shen Brigid Simms-Acuna Sheila Skidmore Patrick M A Sleiman Cathrine Smestad Per Soelberg Sørensen Helle Bach Søndergaard Jim Stankovich Richard C Strange Anna-Maija Sulonen Emilie Sundqvist Ann-Christine Syvänen Francesca Taddeo Bruce Taylor Jenefer M Blackwell Pentti Tienari Elvira Bramon Ayman Tourbah Matthew A Brown Ewa Tronczynska Juan P Casas Niall Tubridy Aiden Corvin Jane Vickery Janusz Jankowski Pablo Villoslada Hugh S Markus Kai Wang Christopher G Mathew James Wason Colin N A Palmer H-Erich Wichmann Robert Plomin Ernest Willoughby Anna Rautanen Juliane Winkelmann Michael Wittig Richard C Trembath Jacqueline Yaouanq Ananth C Viswanathan Haitao Zhang Nicholas W Wood Rebecca Zuvich Panos Deloukas Cordelia Langford Audrey Duncanson Jorge R Oksenberg Margaret A Pericak-Vance Jonathan L Haines Tomas Olsson Jan Hillert Adrian J Ivinson Philip L De Jager Leena Peltonen Graeme J Stewart David A Hafler Stephen L Hauser Gil McVean Peter Donnelly Alastair Compston

Nature 2011 Aug 10;476(7359):214-9. Epub 2011 Aug 10.

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http://dx.doi.org/10.1038/nature10251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182531PMC
August 2011

Interferon-beta increases systemic BAFF levels in multiple sclerosis without increasing autoantibody production.

Mult Scler 2011 May 22;17(5):567-77. Epub 2010 Dec 22.

Institute for Inflammation Research, Department of Rheumatology, Copenhagen University Hospital, Rigshospitalet, Denmark.

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http://dx.doi.org/10.1177/1352458510393771DOI Listing
May 2011

Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course.

Mult Scler 2011 Mar 6;17(3):335-43. Epub 2010 Dec 6.

Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1177/1352458510389102DOI Listing
March 2011

Osteopontin concentrations are increased in cerebrospinal fluid during attacks of multiple sclerosis.

Mult Scler 2011 Jan 4;17(1):32-42. Epub 2010 Oct 4.

University of Copenhagen and Danish MS Research Center, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458510382247DOI Listing
January 2011

T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis.

Immunology 2008 Oct 4;125(2):161-9. Epub 2008 Apr 4.

Institute for Inflammation Research, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/j.1365-2567.2008.02837.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561132PMC
October 2008

The effect of beta-interferon therapy on myelin basic protein-elicited CD4+ T cell proliferation and cytokine production in multiple sclerosis.

Clin Immunol 2008 Oct 23;129(1):80-9. Epub 2008 Jul 23.

Institute for Inflammation Research, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.clim.2008.06.007DOI Listing
October 2008

Oral fumarate for relapsing-remitting multiple sclerosis.

Lancet 2008 Oct;372(9648):1447-8

Danish Multiple Sclerosis Research Center, Department of Neurology, Rigshospitalet, DK-2100, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/S0140-6736(08)61605-0DOI Listing
October 2008

[Biological treatment of multiple sclerosis].

Ugeskr Laeger 2008 Jun;170(24):2156-9

Rigshospitalet, Dansk Multipel Sclerose Center, Neurologisk Afdeling 2082, København Ø.

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June 2008

[Multiple sclerosis--the significance of genes. The Danish Society of Neurology].

Ugeskr Laeger 2008 Mar;170(12):1046

Dansk Multipel Sclerose Center, Neurologisk Klinik 2082, Rigshospitalet, DK-2100 København Ø.

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March 2008

[Treatment of multiple sclerosis--now and in future. The Danish Multiple Sclerosis Society and the Danish Multiple Sclerosis Group].

Ugeskr Laeger 2007 Mar;169(12):1121

Neurologisk Klinik, Rigshospitalet, DK-2100 København Ø.

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March 2007

Recommended standard of cerebrospinal fluid analysis in the diagnosis of multiple sclerosis: a consensus statement.

Arch Neurol 2005 Jun;62(6):865-70

Department of Medicine (Neurology), University of Ottawa, Multiple Sclerosis Research Clinic, The Ottawa Hospital, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1001/archneur.62.6.865DOI Listing
June 2005

Methylprednisolone treatment, immune activation, and intrathecal inflammation in multiple sclerosis.

Authors:
Finn Sellebjerg

Dan Med Bull 2004 May;51(2):167-83

Department of Neurology, University of Copenhagen, Glostrup Hospital, Glostrup, Denmark.

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May 2004