Filippo De Marinis

Filippo De Marinis

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Filippo De Marinis

Filippo De Marinis

Publications by authors named "Filippo De Marinis"

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Immunotherapy in refractory SCLC: the caterpillar struggling to become a butterfly.

Pulmonology 2018 Nov - Dec;24(6):321-322

Division of Thoracic Oncology, IEO, European Institute of Oncology IRCCS, Milan.

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http://dx.doi.org/10.1016/j.pulmoe.2018.12.001DOI Listing
September 2019

Immunotherapy in Non-Small-Cell Lung Cancer Patients With Performance Status 2: Clinical Decision Making With Scant Evidence.

J Clin Oncol 2019 Aug 17;37(22):1863-1867. Epub 2019 Apr 17.

1European Institute of Oncology, IRCCS, Milan, Italy.

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https://ascopubs.org/doi/10.1200/JCO.18.02118
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http://dx.doi.org/10.1200/JCO.18.02118DOI Listing
August 2019

Understanding the Mechanisms of Resistance in -Positive NSCLC: From Tissue to Liquid Biopsy to Guide Treatment Strategy.

Int J Mol Sci 2019 Aug 14;20(16). Epub 2019 Aug 14.

Unit of Clinical Pharmacology and Pharmacogenetics, Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.

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http://dx.doi.org/10.3390/ijms20163951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720634PMC
August 2019

Brain metastases in EGFR-positive non-small cell lung cancer: the way to the becomes less winding.

Ann Transl Med 2019 Jul;7(Suppl 3):S80

Division of Thoracic Oncology, IEO, European Institute of Oncology IRCCS, Milan 20141, Italy.

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http://dx.doi.org/10.21037/atm.2019.04.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685842PMC
July 2019

Pneumonectomy in Stage IIIA-N2 NSCLC: Should It Be Considered After Neoadjuvant Chemotherapy?

Clin Lung Cancer 2019 03 24;20(2):97-106.e1. Epub 2018 Oct 24.

Division of Thoracic Surgery, European Institute of Oncology, University of Milan, Milan, Italy; University of Milan, Department of Oncology and Hemato-oncology, Milan, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S15257304183026
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http://dx.doi.org/10.1016/j.cllc.2018.10.005DOI Listing
March 2019

Molecular Profile of Advanced Non-Small Cell Lung Cancers in Octogenarians: The Door to Precision Medicine in Elderly Patients.

J Clin Med 2019 Jan 18;8(1). Epub 2019 Jan 18.

Unit of Histopathology and Molecular Diagnostics, Division of Pathology, IEO, European Institute of Oncology IRCCS, 20141 Milan, Italy.

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http://dx.doi.org/10.3390/jcm8010112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352111PMC
January 2019

Ensartinib (X-396) a novel drug for anaplastic lymphoma kinasepositive non-small cell lung cancer patients: we need smart trials to avoid wasting good bullets.

Chin Clin Oncol 2018 Oct 15. Epub 2018 Oct 15.

Division of Thoracic Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy.

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http://dx.doi.org/10.21037/cco.2018.09.03DOI Listing
October 2018

The immune profile of EGFR-mutated non-small-cell lung cancer at disease onset and progression after tyrosine kinase inhibitors therapy.

Immunotherapy 2018 09;10(12):1041-1045

Division of Pathology & Laboratory Medicine, European Institute of Oncology, Via Ripamonti 451, 20141 Milan, Italy.

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http://dx.doi.org/10.2217/imt-2018-0027DOI Listing
September 2018

Concise Review: Resistance to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer: The Role of Cancer Stem Cells.

Stem Cells 2018 05 5;36(5):633-640. Epub 2018 Feb 5.

Clinical Pharmacology and Pharmacogenetics Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1002/stem.2787DOI Listing
May 2018

Acquired Resistance to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancers: The Role of Next-Generation Sequencing on Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration Samples.

Arch Pathol Lab Med 2018 Apr;142(4):465-473

From the Divisions of Pathology (Drs Guerini-Rocco, Casadio, Midolo De Luca, and Barberis, and Mr Vacirca), Thoracic Oncology (Drs Passaro and de Marinis), and Thoracic Surgery (Dr Guarize), European Institute of Oncology, Milan, Italy.

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http://dx.doi.org/10.5858/arpa.2017-0158-RADOI Listing
April 2018

Dacomitinib in EGFR-positive non-small cell lung cancer: an attractive but broken option.

Transl Lung Cancer Res 2018 Apr;7(Suppl 2):S100-S102

Division of Thoracic Oncology, European Institute of Oncology, IEO, Milan, Italy.

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http://dx.doi.org/10.21037/tlcr.2018.02.09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943218PMC
April 2018

Induction chemotherapy, extrapleural pneumonectomy and adjuvant radiotherapy for malignant pleural mesothelioma.

Eur J Cardiothorac Surg 2017 Nov;52(5):975-981

Division of Thoracic Surgery, European Institute of Oncology, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1093/ejcts/ezx122DOI Listing
November 2017

Lung Tissue Injury as an Atypical Response to Nivolumab in Non-Small Cell Lung Cancer.

Am J Respir Crit Care Med 2017 Nov;196(10):1349-1350

2 Division of Thoracic Oncology, European Institute of Oncology, Milan, Italy; and.

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http://dx.doi.org/10.1164/rccm.201705-0875IMDOI Listing
November 2017

Combination immunotherapy strategies in advanced non-small cell lung cancer (NSCLC): Does biological rationale meet clinical needs?

Crit Rev Oncol Hematol 2017 Nov 19;119:30-39. Epub 2017 Sep 19.

Medical Oncology 2, Istituto Oncologico Veneto IRCCS, Padova, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2017.09.007DOI Listing
November 2017

Salvage Surgery After Definitive Chemoradiotherapy for Non-small Cell Lung Cancer.

Semin Thorac Cardiovasc Surg 2017 Summer;29(2):233-241. Epub 2017 Feb 24.

Division of Thoracic Surgery, European Institute of Oncology, Milan, Italy; Department of Hematology and Oncology (DIPO), University of Milan, Milan, Italy.

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http://dx.doi.org/10.1053/j.semtcvs.2017.02.001DOI Listing
September 2017

Outcome of Patients With pN2 "Potentially Resectable" Nonsmall Cell Lung Cancer Who Underwent Surgery After Induction Chemotherapy.

Semin Thorac Cardiovasc Surg 2016 Summer;28(2):593-602. Epub 2015 Dec 10.

Division of Thoracic Oncology, European Institute of Oncology, Milan, Italy.

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http://dx.doi.org/10.1053/j.semtcvs.2015.12.001DOI Listing
June 2017

Targeting EGFR T790M mutation in NSCLC: From biology to evaluation and treatment.

Pharmacol Res 2017 03 12;117:406-415. Epub 2017 Jan 12.

Division of Thoracic Oncology, European Institute of Oncology, Milan, Italy.

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http://dx.doi.org/10.1016/j.phrs.2017.01.003DOI Listing
March 2017

[Nivolumab in second-line treatment of squamous non-small cell lung cancer.]

Recenti Prog Med 2016 Dec;107(12):634-640

Divisione di Oncologia Toracica, Istituto Europeo di Oncologia, Milano.

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http://dx.doi.org/10.1701/2502.26230DOI Listing
December 2016

Afatinib for the first-line treatment of patients with metastatic EGFR-positive NSCLC: a look at the data.

Expert Rev Clin Pharmacol 2016 Oct 20;9(10):1283-1288. Epub 2016 Sep 20.

a Division of Thoracic Oncology , European Institute of Oncology , Milan , Italy.

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http://dx.doi.org/10.1080/17512433.2016.1233059DOI Listing
October 2016

Dramatic Antitumor Activity of Nivolumab in Advanced HER2-Positive Lung Cancer.

Clin Lung Cancer 2016 09 4;17(5):e179-e183. Epub 2016 Jun 4.

Thoracic Division, Medical Oncology Department, European Institute of Oncology, Milan, Italy.

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http://dx.doi.org/10.1016/j.cllc.2016.05.004DOI Listing
September 2016

Efficacy and safety of rechallenge treatment with gefitinib in patients with advanced non-small cell lung cancer.

Lung Cancer 2016 09 14;99:31-7. Epub 2016 Jun 14.

Thoracic Oncology Division, Istituto Europeo di Oncologia (IEO), Via Ripamonti 435, 20141 Milan, Italy, Italy; Formerly Department of Thoracic Oncology, 1st Pulmonary Oncological Unit, Azienda Ospedaliera San Camillo-Forlanini, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2016.06.008DOI Listing
September 2016

First-line treatment in NSCLC harboring EGFR common mutations: EGFR TKI in monotherapy or in combination with anti-VEGF?

Expert Rev Anticancer Ther 2016 08 15;16(8):799-801. Epub 2016 Jul 15.

a Division of Thoracic Oncology , European Institute of Oncology , Milan , Italy.

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http://dx.doi.org/10.1080/14737140.2016.1210007DOI Listing
August 2016

Multicenter Phase II Study of Whole-Body and Intracranial Activity With Ceritinib in Patients With ALK-Rearranged Non-Small-Cell Lung Cancer Previously Treated With Chemotherapy and Crizotinib: Results From ASCEND-2.

J Clin Oncol 2016 08 18;34(24):2866-73. Epub 2016 Jul 18.

Lucio Crinò, University Medical School of Perugia, Azienda Ospedale Perugia, Perugia; Filippo De Marinis, European Institute of Oncology, Milan; Giorgio Scagliotti, University of Torino, Torino, Italy; Myung-Ju Ahn, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, South Korea; Harry J.M. Groen, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; Heather Wakelee, Stanford University Medical Center, Stanford, CA; Toyoaki Hida, Aichi Cancer Center, Nagoya; Makoto Nishio, Japanese Foundation for Cancer Research, Tokyo, Japan; Tony Mok, Chinese University of Hong Kong, Shatin, China; David Spigel, Sarah Cannon Research Institute, Nashville, TN; Enriqueta Felip, Vall d'Hebron University, Barcelona, Spain; Fabrice Branle and Massimiliano Quadrigli, Novartis Pharma AG, Basel, Switzerland; Chetachi Emeremni and Jie Zhang, Novartis Pharma, East Hanover, NJ; and Alice T. Shaw, Massachusetts General Hospital, Boston MA.

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http://ascopubs.org/doi/10.1200/JCO.2015.65.5936
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http://dx.doi.org/10.1200/JCO.2015.65.5936DOI Listing
August 2016

[Immunotherapy in non-small cell lung cancer: evolution of knowledge and clinical advances].

Recenti Prog Med 2016 Apr;107(4):186-92

Divisione di Oncologia Toracica, Istituto Europeo di Oncologia, Milano.

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http://dx.doi.org/10.1701/2218.23930DOI Listing
April 2016

Cellular and molecular biology of small cell lung cancer: an overview.

Transl Lung Cancer Res 2016 Feb;5(1):2-15

1 Instituto Oncolόgico Dr Rosell, Quirón Dexeus University Hospital, Barcelona, Spain ; 2 Department of Medical Oncology, University of Verona, Azienda Ospedaliera Universitaria Integrata, Verona, Italy ; 3 Division of Thoracic Oncology, European Institute of Oncology (IEO), Milan, Italy ; 4 Pangaea Biotech, Barcelona, Spain ; 5 Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona, Spain ; 6 Molecular Oncology Research (MORe) Foundation, Barcelona, Spain ; 7 Germans Trias i Pujol Health Sciences Institute and Hospital, Campus Can Ruti, Badalona, Barcelona, Spain.

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http://dx.doi.org/10.3978/j.issn.2218-6751.2016.01.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758976PMC
February 2016

The role of extended pulmonary metastasectomy.

J Thorac Oncol 2015 Jun;10(6):924-9

*Division of Thoracic Surgery, European Institute of Oncology, University of Milan, Milan, Italy; †Division of Epidemiology and Biostatistics, ‡Division Clinical Oncology, European Institute of Oncology, Milan, Italy; and §School of Medicine, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1097/JTO.0000000000000547DOI Listing
June 2015

PET/CT characterization of non-small-cell lung cancer heterogeneity.

Nucl Med Commun 2015 May;36(5):411-3

aDivision of Nuclear Medicine bThoracic Oncology Division, European Institute of Oncology, Milan, Italy.

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http://dx.doi.org/10.1097/MNM.0000000000000270DOI Listing
May 2015

Erlotinib efficacy in NSCLC patients with high polysomy of chromosome 7 and EGFR/KRas wild-type tumors.

J Thorac Oncol 2015 Feb;10(2):392-6

*Medical Oncology Department, Thoracic Oncology Division, and †Pathology and Laboratory Medicine Department, Pathology Division, European Institute of Oncology, Milan, Italy.

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http://dx.doi.org/10.1097/JTO.0000000000000355DOI Listing
February 2015

Diagnostic and therapeutic issues for patients with advanced non‑small cell lung cancer harboring anaplastic lymphoma kinase rearrangement: European vs. US perspective (review).

Int J Oncol 2014 Aug 21;45(2):509-15. Epub 2014 May 21.

Division of Medical Oncology, San Giuseppe Moscati Hospital, I-83100 Avellino, Italy.

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http://dx.doi.org/10.3892/ijo.2014.2453DOI Listing
August 2014

Final efficacy and safety results of pemetrexed continuation maintenance therapy in the elderly from the PARAMOUNT phase III study.

J Thorac Oncol 2014 Jul;9(7):991-7

*Division of Medical Oncology, S. Giuseppe Moscati Hospital, Avellino, Italy; †Department of Lung Diseases, San Camillo Hospital, Rome, Italy; ‡Internistische Onkologie der Thoraxtumoren, Thoraxklinik im Universitätsklinikum Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Heidelberg, Germany; §Department of Medical Oncology, Tata Memorial Hospital, Mumbai, India; ‖Centre Catherine De Sienne, Nantes, France; ¶Christie Hospital NHS Foundation Trust, Manchester, England; #CHR La Citadelle, Liege, Belgium; **Centre Hospitalier Regional Universitaire de Montpellier, Montpellier, France; ††Eli Lilly and Company, Indianapolis, IN; ‡‡Eli Lilly and Company, Madrid, Spain; §§Eli Lilly and Company, Neuilly-sur-Seine Cedex, France; ‖‖Eli Lilly and Company, Houten, The Netherlands; and ¶¶University Hospital, Virgen del Rocio, Seville, Spain.

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http://dx.doi.org/10.1097/JTO.0000000000000207DOI Listing
July 2014

management of nonhematologic toxicities associated with different EGFR-TKIs in advanced NSCLC: a comparison analysis.

Clin Lung Cancer 2014 Jul 12;15(4):307-12. Epub 2014 May 12.

Division of Thoracic Oncology, European Institute of Oncology (IEO), Milan, Italy.

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http://dx.doi.org/10.1016/j.cllc.2014.04.006DOI Listing
July 2014

ROR1 as a novel therapeutic target for EGFR-mutant non-small-cell lung cancer patients with the EGFR T790M mutation.

Transl Lung Cancer Res 2014 Jun;3(3):122-30

1 Dr Rosell Oncology Institute, 2 Pangaea Biotech S.L, Quirón Dexeus University Hospital, Barcelona, Spain ; 3 Pivotal CRO, Madrid, Spain ; 4 Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona, Spain ; 5 Hospital General de Alicante, Alicante, Spain ; 6 CHU Limoges, Limoges, France ; 7 European Institute of Oncology (IEO), Milan, Italy ; 8 Molecular Oncology Research (MORe) Foundation, Barcelona, Spain.

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http://dx.doi.org/10.3978/j.issn.2218-6751.2014.03.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367691PMC
June 2014