Filippo Belardelli

Filippo Belardelli

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Filippo Belardelli

Publications by authors named "Filippo Belardelli"

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International Accreditation of Cancer Centres of Italian Network of Alleanza contro il Cancro: introductory remarks.

Tumori 2015 30;101 Suppl 1. Epub 2015 Dec 30.

President of Alleanza contro il Cancro, Istituto Regina Elena, IRCCS, Regina Elena National Cancer Institute, Rome - Italy.

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http://dx.doi.org/10.5301/tj.5000454DOI Listing
September 2016

Application of OECI accreditation program to cancer institutes of the Alleanza Contro il Cancro Italian Network: a special project supported by the Italian Ministry of Health.

Tumori 2015 30;101 Suppl 1:S2-5. Epub 2015 Dec 30.

Ematology, Oncology and Molecular Medicine Department, Istituto Superiore Sanità, Rome - Italy.

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http://dx.doi.org/10.5301/tj.5000455DOI Listing
September 2016

NK Cell Activation in the Antitumor Response Induced by IFN-α Dendritic Cells Loaded with Apoptotic Cells from Follicular Lymphoma Patients.

J Immunol 2016 08 29;197(3):795-806. Epub 2016 Jun 29.

Reparto di Immunoterapia Sperimentale, Dipartimento di Ematologia, Oncologia e Medicina Sperimentale, Istituto Superiore di Sanità, 00161 Rome, Italy;

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http://dx.doi.org/10.4049/jimmunol.1600262DOI Listing
August 2016

The European Research Infrastructures of the ESFRI Roadmap in Biological and Medical Sciences: status and perspectives.

Ann Ist Super Sanita 2014 ;50(2):178-85

Dipartimento di Ematologia, Oncologia e Medicina Molecolare, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.4415/ANN_14_02_12DOI Listing
September 2015

A semi-automatic web based tool for the selection of research projects reviewers.

Stud Health Technol Inform 2014 ;205:950-4

Department of Informatics, Bioengineering, Robotics and System Engineering, University of Genoa, Via Opera Pia 13, 16145 Genoa, Italy.

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May 2015

Role of type I interferon in inducing a protective immune response: perspectives for clinical applications.

Cytokine Growth Factor Rev 2015 Apr 30;26(2):195-201. Epub 2014 Oct 30.

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.cytogfr.2014.10.002DOI Listing
April 2015

Interferon fundamentals: a tribute to the scientific vision of G B Rossi. Editorial.

Cytokine Growth Factor Rev 2015 Apr 26;26(2):95-7. Epub 2014 Dec 26.

Istituto Superiore di Sanità, Roma, Italy.

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http://dx.doi.org/10.1016/j.cytogfr.2014.12.003DOI Listing
April 2015

Type I interferons as regulators of human antigen presenting cell functions.

Toxins (Basel) 2014 May 26;6(6):1696-723. Epub 2014 May 26.

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, Rome 00161, Italy.

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http://dx.doi.org/10.3390/toxins6061696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073125PMC
May 2014

Opposite regulatory effects of IFN-β and IL-3 on C-type lectin receptors, antigen uptake, and phagocytosis in human macrophages.

J Leukoc Biol 2014 Jan 9;95(1):161-8. Epub 2013 Sep 9.

1.Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1189/jlb.0313168DOI Listing
January 2014

Exploiting dendritic cells in the development of cancer vaccines.

Expert Rev Vaccines 2013 Oct 4;12(10):1195-210. Epub 2013 Oct 4.

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1586/14760584.2013.836905DOI Listing
October 2013

Cyclophosphamide induces a type I interferon-associated sterile inflammatory response signature in cancer patients' blood cells: implications for cancer chemoimmunotherapy.

Clin Cancer Res 2013 Aug 12;19(15):4249-61. Epub 2013 Jun 12.

Department of Hematology Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, Rome 00161, Italy.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-3666DOI Listing
August 2013

Cross talk between cancer and immune cells: exploring complex dynamics in a microfluidic environment.

Lab Chip 2013 Jan 30;13(2):229-39. Epub 2012 Oct 30.

Italian National Research Council-Institute for Photonics and Nanotechnologies (CNR-IFN), Via Cineto Romano 42, Rome, 00156, Italy.

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http://dx.doi.org/10.1039/c2lc40887bDOI Listing
January 2013

Ninth annual meeting of the Italian Network for Tumor Biotherapy (NIBIT), Siena, Italy, October 19-22, 2011: New perspectives in the immunotherapy of cancer.

Cancer Immunol Immunother 2012 Sep 27;61(9):1599-608. Epub 2012 Jun 27.

Division of Medical Oncology and Immunotherapy, Department of Oncology, University Hospital of Siena, Istituto Toscano Tumori, Viale Mario Bracci n 16, 53100 Siena, Italy.

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http://link.springer.com/10.1007/s00262-012-1304-7
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http://dx.doi.org/10.1007/s00262-012-1304-7DOI Listing
September 2012

Interferon-α as antiviral and antitumor vaccine adjuvants: mechanisms of action and response signature.

J Interferon Cytokine Res 2012 Jun 10;32(6):235-47. Epub 2012 Apr 10.

Department of Haematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy .

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http://dx.doi.org/10.1089/jir.2011.0077DOI Listing
June 2012

Exploitation of the propulsive force of chemotherapy for improving the response to cancer immunotherapy.

Mol Oncol 2012 Feb 3;6(1):1-14. Epub 2011 Dec 3.

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1016/j.molonc.2011.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528384PMC
February 2012

IFN-α enhances cross-presentation in human dendritic cells by modulating antigen survival, endocytic routing, and processing.

Blood 2012 Feb 19;119(6):1407-17. Epub 2011 Dec 19.

Department of Cell Biology and Neurosciences, Section of Experimental Immunotherapy, Istituto Superiore di Sanità, Viale Regina Elena 299, Rome, Italy;

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http://dx.doi.org/10.1182/blood-2011-06-363564DOI Listing
February 2012

Translational research on advanced therapies.

Ann Ist Super Sanita 2011 ;47(1):72-8

Dipartimento di Biologia Cellulare e Neuroscienze, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.4415/ANN_11_01_15DOI Listing
July 2011

Eighth annual meeting of the Italian network for tumor biotherapy (NIBIT), Siena, October 7-9, 2010.

Cancer Immunol Immunother 2011 Jun 24;60(6):901-7. Epub 2011 Mar 24.

Division of Medical Oncology and Immunotherapy, Department of Oncology, University Hospital of Siena, Istituto Toscano Tumori, Strada delle Scotte 14, 53100, Siena, Italy.

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http://dx.doi.org/10.1007/s00262-011-1006-6DOI Listing
June 2011

IFN-α boosts epitope cross-presentation by dendritic cells via modulation of proteasome activity.

Immunobiology 2011 May 21;216(5):537-47. Epub 2010 Oct 21.

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1016/j.imbio.2010.10.003DOI Listing
May 2011

Unraveling cancer chemoimmunotherapy mechanisms by gene and protein expression profiling of responses to cyclophosphamide.

Cancer Res 2011 May 28;71(10):3528-39. Epub 2011 Mar 28.

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-4523DOI Listing
May 2011

IFN-α as a vaccine adjuvant: recent insights into the mechanisms and perspectives for its clinical use.

Expert Rev Vaccines 2011 Apr;10(4):487-98

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1586/erv.11.9DOI Listing
April 2011

Seventh annual meeting of the Italian Network for Tumor Biotherapy (NIBIT), Siena, 1-3 October 2009.

Cancer Immunol Immunother 2010 Dec 5;59(12):1895-901. Epub 2010 Mar 5.

Department of Oncology, Istituto Toscano Tumori, University Hospital of Siena, Strada delle Scotte 14, 53100, Siena, Italy.

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http://dx.doi.org/10.1007/s00262-010-0832-2DOI Listing
December 2010

Sixth annual meeting of the Italian network for tumor biotherapy (NIBIT), Siena, 16-18 October 2008.

Cancer Immunol Immunother 2010 Jun 28;59(6):963-9. Epub 2009 Mar 28.

Division of Medical Oncology and Immunotherapy, Department of Oncology, University Hospital of Siena, Istituto Toscano Tumori, Strada delle Scotte 14, 53100, Siena, Italy.

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http://dx.doi.org/10.1007/s00262-009-0696-5DOI Listing
June 2010

APC activation by IFN-alpha decreases regulatory T cell and enhances Th cell functions.

J Immunol 2010 Jun 28;184(11):5969-79. Epub 2010 Apr 28.

Immunology Laboratory, Department of Biology, University of Rome Tor Vergata, Rome, Italy.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.0900526
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http://dx.doi.org/10.4049/jimmunol.0900526DOI Listing
June 2010

Recent advances on the immunomodulatory effects of IFN-alpha: implications for cancer immunotherapy and autoimmunity.

Autoimmunity 2010 Apr;43(3):204-9

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy.

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http://dx.doi.org/10.3109/08916930903510880DOI Listing
April 2010

Combination strategies for enhancing the efficacy of immunotherapy in cancer patients.

Ann N Y Acad Sci 2010 Apr;1194:169-78

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.1111/j.1749-6632.2010.05464.xDOI Listing
April 2010

LOX-1 as a natural IFN-alpha-mediated signal for apoptotic cell uptake and antigen presentation in dendritic cells.

Blood 2010 Feb 15;115(8):1554-63. Epub 2009 Dec 15.

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Viale Regina Elena 299, Rome, Italy.

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http://dx.doi.org/10.1182/blood-2009-07-234468DOI Listing
February 2010

Type I IFN regulate DC turnover in vivo.

Eur J Immunol 2009 Jul;39(7):1807-18

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.1002/eji.200939233DOI Listing
July 2009

IFN-alpha in the generation of dendritic cells for cancer immunotherapy.

Handb Exp Pharmacol 2009 (188):295-317

Section of Experimental Immunotherapy, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Viale Regina Elena, Rome, 299, 00161 Italy.

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http://dx.doi.org/10.1007/978-3-540-71029-5_14DOI Listing
February 2009

Biotherapy of cancer: break the barriers to foster translation of knowledge.

Tumori 2008 Mar-Apr;94(2):182-7

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy.

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July 2008

Type I interferons as vaccine adjuvants against infectious diseases and cancer.

Expert Rev Vaccines 2008 Apr;7(3):373-81

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1586/14760584.7.3.373DOI Listing
April 2008

Role of the cytokine environment and cytokine receptor expression on the generation of functionally distinct dendritic cells from human monocytes.

Eur J Immunol 2008 Mar;38(3):750-62

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.1002/eji.200737395DOI Listing
March 2008

Cytokines, dendritic cells and immunological rejection.

Cytokine Growth Factor Rev 2008 Feb 3;19(1):1-2. Epub 2007 Dec 3.

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http://dx.doi.org/10.1016/j.cytogfr.2007.10.002DOI Listing
February 2008

Dendritic cells and cytokines in immune rejection of cancer.

Cytokine Growth Factor Rev 2008 Feb 3;19(1):93-107. Epub 2007 Dec 3.

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Viale Regina Elena, 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1016/j.cytogfr.2007.10.003DOI Listing
February 2008

Interferon-alpha and cancer: mechanisms of action and new perspectives of clinical use.

Biochimie 2007 Jun-Jul;89(6-7):884-93. Epub 2007 Apr 21.

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1016/j.biochi.2007.04.006DOI Listing
September 2007

IFN-alpha and novel strategies of combination therapy for cancer.

Ann N Y Acad Sci 2007 Sep 13;1112:256-68. Epub 2007 Jun 13.

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, viale Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1196/annals.1415.030DOI Listing
September 2007

Role of endogenous interferon and LPS in the immunomodulatory effects of bovine lactoferrin in murine peritoneal macrophages.

J Leukoc Biol 2007 Aug 2;82(2):347-53. Epub 2007 May 2.

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.1189/jlb.1106688DOI Listing
August 2007

International meeting "Immunotherapy of cancer: challenges and needs".

Cancer Immunol Immunother 2007 Apr 28;56(4):581-5. Epub 2006 Nov 28.

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1007/s00262-006-0251-6DOI Listing
April 2007

Differentiation of monocyte-derived dendritic cells is associated with upregulation and activation of Rac-1 small GTPase.

FEBS Lett 2006 May 8;580(13):3335-9. Epub 2006 May 8.

Department of Drug Research and Evaluation, Istituto Superiore di Sanita', viale Regina Elena 299, 00161, Rome, Italy.

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http://dx.doi.org/10.1016/j.febslet.2006.04.095DOI Listing
May 2006

Type I IFN as a vaccine adjuvant for both systemic and mucosal vaccination against influenza virus.

Vaccine 2006 Apr;24 Suppl 2:S2-56-7

Department of Cellular Biology and Neurosciences, Istituto Superiore di Sanità, V. le Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1016/j.vaccine.2005.01.121DOI Listing
April 2006

IL-2 induces expression and secretion of IFN-gamma in murine peritoneal macrophages.

J Leukoc Biol 2005 Sep 10;78(3):686-95. Epub 2005 Jun 10.

Department of Cell Biology and Neurosciences, Viale Regina Elena 299, 00161 Rome, Italy.

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http://doi.wiley.com/10.1189/jlb.0105035
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http://dx.doi.org/10.1189/jlb.0105035DOI Listing
September 2005

Type I interferons as regulators of the differentiation/activation of human dendritic cells: methods for the evaluation of IFN-induced effects.

Methods Mol Med 2005 ;116:167-81

Department of Cell Biolology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.1385/1-59259-939-7:167DOI Listing
September 2005

IRF-4 expression in the human myeloid lineage: up-regulation during dendritic cell differentiation and inhibition by 1alpha,25-dihydroxyvitamin D3.

J Leukoc Biol 2005 Jun 13;77(6):944-7. Epub 2005 Apr 13.

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.1189/jlb.0205090DOI Listing
June 2005

Immunomodulatory effects of the HIV-1 gp120 protein on antigen presenting cells: implications for AIDS pathogenesis.

Immunobiology 2004 ;209(1-2):99-115

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Viale Regina Elena, 299, Rome 00161, Italy.

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http://dx.doi.org/10.1016/j.imbio.2004.02.008DOI Listing
May 2005

Pertussis toxin B-oligomer inhibits HIV infection and replication in hu-PBL-SCID mice.

Int Immunol 2005 Apr 3;17(4):469-75. Epub 2005 Mar 3.

Department of Cellular Biology and Neurosciences, Istituto Superiore di Sanità, 00161 Rome, Italy.

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http://dx.doi.org/10.1093/intimm/dxh226DOI Listing
April 2005

Type I IFN is a powerful mucosal adjuvant for a selective intranasal vaccination against influenza virus in mice and affects antigen capture at mucosal level.

Vaccine 2005 Apr;23(23):2994-3004

Department of Cell Biology and Neurosciences, Parasitic and Immune-mediated Diseases, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1016/j.vaccine.2004.12.006DOI Listing
April 2005

Reciprocal activating interaction between dendritic cells and pamidronate-stimulated gammadelta T cells: role of CD86 and inflammatory cytokines.

J Immunol 2005 Jan;174(1):252-60

Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.4049/jimmunol.174.1.252DOI Listing
January 2005

A type I IFN-dependent pathway induced by Schistosoma mansoni eggs in mouse myeloid dendritic cells generates an inflammatory signature.

J Immunol 2004 Mar;172(5):3011-7

Centre d'Immunologie et de Biologie Parasitaire, Institut National de la Santé et de la Recherche Médicale, Unité 547, Institut Pasteur de Lille, Lille, France.

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http://dx.doi.org/10.4049/jimmunol.172.5.3011DOI Listing
March 2004