Filip De Keyser

Filip De Keyser

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Filip De Keyser

Filip De Keyser

Publications by authors named "Filip De Keyser"

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Pitfalls in the detection of myositis specific antibodies by lineblot in clinically suspected idiopathic inflammatory myopathy.

Clin Exp Rheumatol 2019 Jul 4. Epub 2019 Jul 4.

Department of Laboratory Medicine, Ghent University Hospital, and Department of Diagnostic Science, Ghent University, Belgium.

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July 2019

A prospective, longitudinal study evaluating the baseline six-minute walk test as an individual reference value in systemic sclerosis patients.

Clin Exp Rheumatol 2018 Jul-Aug;36 Suppl 113(4):95-101. Epub 2018 Aug 28.

Department of Internal Medicine, Ghent University, and Department of Rheumatology, Ghent University Hospital, Belgium.

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January 2019

Is laser speckle contrast analysis (LASCA) the new kid on the block in systemic sclerosis? A systematic literature review and pilot study to evaluate reliability of LASCA to measure peripheral blood perfusion in scleroderma patients.

Autoimmun Rev 2018 Aug 6;17(8):775-780. Epub 2018 Jun 6.

Department of Rheumatology, Ghent University Hospital, Department of Internal Medicine, Ghent University, Corneel Heymanslaan 10, Ghent, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.autrev.2018.01.023DOI Listing
August 2018

Nailfold capillaroscopy in systemic lupus erythematosus: A systematic review and critical appraisal.

Autoimmun Rev 2018 Apr 8;17(4):344-352. Epub 2018 Feb 8.

Department of Rheumatology, Ghent University Hospital, C. Heymanslaan 10, Ghent, Belgium; Department of Internal Medicine, Ghent University, C. Heymanslaan 10, Ghent, Belgium. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15689972183003
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http://dx.doi.org/10.1016/j.autrev.2017.11.025DOI Listing
April 2018

Six-minute walk test in or out in evaluation of systemic sclerosis patients?

Clin Exp Rheumatol 2017 Sep-Oct;35 Suppl 106(4):122-129. Epub 2017 Feb 15.

Department of Rheumatology, Ghent University Hospital; and Department of Internal Medicine, Ghent University, Belgium.

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December 2017

Disease activity indices in systemic sclerosis: a systematic literature review.

Clin Exp Rheumatol 2016 Sep-Oct;34 Suppl 100(5):186-192. Epub 2016 Jul 6.

Department of Internal Medicine, Faculty of Medicine and Health Sciences, Ghent University; and Department of Rheumatology, Faculty of Medicine and Health Sciences, Ghent University, Belgium.

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January 2017

Assessment of sensitivity to change of the European Scleroderma Study Group activity index.

Clin Exp Rheumatol 2016 Sep-Oct;34 Suppl 100(5):148-151. Epub 2016 Jul 18.

Department of Internal Medicine, Faculty of Medicine and Health Sciences, Ghent University; and Department of Rheumatology, Ghent University Hospital, Belgium.

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January 2017

Nailfold Capillaroscopy and Clinical Applications in Systemic Sclerosis.

Microcirculation 2016 07;23(5):364-72

Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genova, Italy.

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http://dx.doi.org/10.1111/micc.12281DOI Listing
July 2016

Fuchs' Uveitis Syndrome: No Longer a Syndrome?

Ocul Immunol Inflamm 2016 Jun 29;24(3):348-57. Epub 2015 Jul 29.

a University Hospital Ghent , Ophthalmology , Ghent , Belgium and.

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http://dx.doi.org/10.3109/09273948.2015.1005239DOI Listing
June 2016

Reliability of the quantitative assessment of peripheral blood perfusion by laser speckle contrast analysis in a systemic sclerosis cohort.

Ann Rheum Dis 2016 06 22;75(6):1263-4. Epub 2016 Mar 22.

Department of Rheumatology, Ghent University Hospital, Ghent, Belgium Department of Internal Medicine, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1136/annrheumdis-2015-208857DOI Listing
June 2016

Six-minute walk test in systemic sclerosis: A systematic review and meta-analysis.

Int J Cardiol 2016 Jun 25;212:265-73. Epub 2016 Mar 25.

Department of Internal Medicine, Ghent University, Ghent, Belgium; Department of Rheumatology, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1016/j.ijcard.2016.03.084DOI Listing
June 2016

The heart and pulmonary arterial hypertension in systemic sclerosis.

Acta Clin Belg 2016 Feb 5;71(1):1-18. Epub 2016 Feb 5.

c Department of Internal Medicine , Ghent University , Ghent , Belgium.

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http://dx.doi.org/10.1080/17843286.2015.1108538DOI Listing
February 2016

Specific Antinuclear Antibody Level Changes after B Cell Depletion Therapy in Systemic Sclerosis Are Associated with Improvement of Skin Thickening.

J Rheumatol 2016 Jan;43(1):247-9

Department of Clinical Chemistry, Microbiology and Immunology, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.3899/jrheum.150105DOI Listing
January 2016

Factors influencing the occupational trajectory of patients with systemic sclerosis: a qualitative study.

Clin Exp Rheumatol 2015 Jul-Aug;33(4 Suppl 91):S26-30. Epub 2015 Mar 20.

Faculty of Medicine and Health Sciences, Department of Public Health - Nursing Science, Ghent University, Belgium.

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October 2015

Longterm followup of rituximab therapy in patients with rheumatoid arthritis: results from the Belgian MabThera in Rheumatoid Arthritis registry.

J Rheumatol 2014 Sep 15;41(9):1761-5. Epub 2014 Aug 15.

From the Department of Rheumatology, Ghent University Hospital, Ghent; GZA St-Augustinus Hospital, Antwerp; Department of Rheumatology, University Hospital Liège, Liège; Pôle de Recherche en Rhumatologie; Institut de Recherche Expérimentale et Clinique; Université Catholique de Louvain and Cliniques Universitaires Saint-Luc, Brussels; Skeletal Biology and Engineering Research Center; the Department of Development and Regeneration; KU Leuven, Leuven, Belgium.F. De Keyser, MD, PhD, Department of Rheumatology, Ghent University Hospital; I. Hoffman, MD, PhD, GZA St-Augustinus Hospital; P. Durez, MD, PhD, Pôle de Recherche en Rhumatologie, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Cliniques Universitaires Saint-Luc; M.J. Kaiser, MD, PhD, Department of Rheumatology, University Hospital Liège; R. Westhovens, MD, PhD, Skeletal Biology and Engineering Research Center, Department of Development and Regeneration, KU Leuven, Rheumatology.

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http://www.jrheum.org/content/41/9/1761.full.pdf
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http://www.jrheum.org/cgi/doi/10.3899/jrheum.131279
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http://dx.doi.org/10.3899/jrheum.131279DOI Listing
September 2014

Ten-year followup of infliximab therapy in rheumatoid arthritis patients with severe, longstanding refractory disease: a cohort study.

J Rheumatol 2014 Jul 1;41(7):1276-81. Epub 2014 Jun 1.

From Department of Rheumatology, Ghent University, Ghent; MSD Belgium BVBA; Department of Rheumatology, Pôle de Recherche en Rhumatologie, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain and Cliniques Universitaires Saint-Luc, Brussels; Skeletal Biology and Engineering Research Center, Department of Development and Regeneration KU Leuven; and Department of Rheumatology, University Hospitals Leuven, Leuven, Belgium.F. De Keyser, MD; J. De Kock, MD, Department of Rheumatology, Ghent University; H. Leroi, MSD Belgium BVBA, Brussels; P. Durez, MD, Department of Rheumatology, Pôle de Recherche en Rhumatologie, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain and Cliniques Universitaires Saint-Luc; R. Westhovens, MD, PhD, Skeletal Biology and Engineering Research Center, Department of Development and Regeneration KU Leuven; and Department of Rheumatology, University Hospitals Leuven.

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.131270
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http://dx.doi.org/10.3899/jrheum.131270DOI Listing
July 2014

Nailfold capillaroscopy for prediction of novel future severe organ involvement in systemic sclerosis.

J Rheumatol 2013 Dec 15;40(12):2023-8. Epub 2013 Oct 15.

From the Department of Rheumatology, Ghent University Hospital, Ghent, Belgium; Department of Internal Medicine and Medical Specialities, University Sapienza, Rome; Research Laboratory and Academic Unit of Clinical Rheumatology, Department of Internal Medicine, University of Genoa, Italy; Department of Internal Medicine, Biostatistics Unit, Department of Public Health, Ghent University, and Department of Laboratory Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.3899/jrheum.130528DOI Listing
December 2013

Quantification of IFNγ- and IL17-producing cells after stimulation with citrullinated proteins in healthy subjects and RA patients.

Rheumatol Int 2013 Oct 24;33(10):2661-4. Epub 2012 Jul 24.

Laboratory for Pharmaceutical Biotechnology, Ghent University, Harelbekestraat 72, 9000, Ghent, Belgium.

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http://dx.doi.org/10.1007/s00296-012-2470-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782635PMC
October 2013

The influence of ageing on the development and management of rheumatoid arthritis.

Nat Rev Rheumatol 2013 Oct 18;9(10):604-13. Epub 2013 Jun 18.

Department of Rheumatology and Clinical Immunology, UMCG, University of Groningen, 9700 RB, Groningen, The Netherlands.

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http://dx.doi.org/10.1038/nrrheum.2013.92DOI Listing
October 2013

Construction and psychometric properties of the Belgian Rheumatoid Arthritis Disability Assessment (BRADA) questionnaire: a new tool for the evaluation of activity limitations in patients with rheumatoid arthritis.

Clin Exp Rheumatol 2013 Jul-Aug;31(4):596-605. Epub 2013 Jul 30.

Department of Rheumatology, Ghent University Hospital, Ghent, Belgium.

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October 2013

Fluoroenzymeimmunoassay to detect systemic sclerosis-associated antibodies: diagnostic performance and correlation with conventional techniques.

Clin Exp Rheumatol 2012 Sep-Oct;30(5):748-55. Epub 2012 Oct 17.

Department of Clinical Chemistry, Ghent University Hospital, Ghent, Belgium.

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February 2013

The Belgian Systemic Sclerosis Cohort: correlations between disease severity scores, cutaneous subsets, and autoantibody profile.

J Rheumatol 2012 Nov 15;39(11):2127-33. Epub 2012 Sep 15.

Rheumatology and Internal Medicine Departments, Cliniques Universitaires Saint-Luc, and Centre Hospitalier Universitaire Mont Godinne, Université Catholique de Louvain, Brussels, Belgium.

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http://www.jrheum.org/cgi/doi/10.3899/jrheum.120283
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http://dx.doi.org/10.3899/jrheum.120283DOI Listing
November 2012

Do worsening scleroderma capillaroscopic patterns predict future severe organ involvement? a pilot study.

Ann Rheum Dis 2012 Oct 8;71(10):1636-9. Epub 2012 Mar 8.

Department of Rheumatology, Ghent University Hospital 0K12-IB, De Pintelaan 185, B-9000, Gent, Belgium.

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http://dx.doi.org/10.1136/annrheumdis-2011-200780DOI Listing
October 2012

Management of inflammatory bowel disease in pregnancy.

J Crohns Colitis 2012 Sep 16;6(8):811-23. Epub 2012 May 16.

Department of Gastroenterology, University Hospital Gasthuisberg, Leuven, Belgium.

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https://academic.oup.com/ecco-jcc/article-lookup/doi/10.1016
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http://dx.doi.org/10.1016/j.crohns.2012.04.009DOI Listing
September 2012

Work participation and work transition in patients with systemic sclerosis: a cross-sectional study.

Rheumatology (Oxford) 2012 Feb 4;51(2):297-304. Epub 2011 Oct 4.

Department of Internal Medicine, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.

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https://academic.oup.com/rheumatology/article-lookup/doi/10.
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http://dx.doi.org/10.1093/rheumatology/ker288DOI Listing
February 2012

Specific anti-nuclear antibodies in systemic sclerosis patients with and without skin involvement: an extended methodological approach.

Rheumatology (Oxford) 2011 Jul 17;50(7):1302-9. Epub 2011 Feb 17.

Department of Rheumatology, Ghent University Hospital, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1093/rheumatology/keq446DOI Listing
July 2011

Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy.

PLoS Genet 2011 Jul 14;7(7):e1002178. Epub 2011 Jul 14.

Department of Epidemiology, M. D. Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1371/journal.pgen.1002178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136437PMC
July 2011

Hand radiological damage in systemic sclerosis: comparison with a control group and clinical and functional correlations.

Semin Arthritis Rheum 2011 Apr 22;40(5):455-60. Epub 2010 Sep 22.

Radiology Department, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium.

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http://linkinghub.elsevier.com/retrieve/pii/S004901721000094
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http://dx.doi.org/10.1016/j.semarthrit.2010.06.008DOI Listing
April 2011

The Belgian MIRA (MabThera In Rheumatoid Arthritis) registry: clues for the optimization of rituximab treatment strategies.

Arthritis Res Ther 2010 10;12(5):R169. Epub 2010 Sep 10.

Department of Rheumatology, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium.

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http://dx.doi.org/10.1186/ar3129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990996PMC
March 2011

Novel autoantibody markers for early and seronegative rheumatoid arthritis.

J Autoimmun 2011 Feb 10;36(1):33-46. Epub 2010 Nov 10.

Hasselt University, Biomedical Research Institute, and Transnationale Universiteit Limburg, School of Life Sciences, Agoralaan, Building C, 3590 Diepenbeek, Belgium.

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http://dx.doi.org/10.1016/j.jaut.2010.10.003DOI Listing
February 2011

Histopathological cutaneous alterations in systemic sclerosis: a clinicopathological study.

Arthritis Res Ther 2011 Feb 28;13(1):R35. Epub 2011 Feb 28.

Department of Rheumatology, Ghent University Hospital, De Pintelaan 185, BE-9000 Gent, Belgium.

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http://dx.doi.org/10.1186/ar3267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241379PMC
February 2011

Seven-year follow-up of infliximab therapy in rheumatoid arthritis patients with severe long-standing refractory disease: attrition rate and evolution of disease activity.

Arthritis Res Ther 2010 6;12(3):R77. Epub 2010 May 6.

Department of Rheumatology, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium.

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http://dx.doi.org/10.1186/ar2997DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911854PMC
November 2010

74-week follow-up of safety of infliximab in patients with refractory rheumatoid arthritis.

Arthritis Res Ther 2010 22;12(3):R121. Epub 2010 Jun 22.

Department of Immunology, Schering-Plough nv, 73 Rue de Stalle, Brussels 1180, Belgium.

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http://dx.doi.org/10.1186/ar3058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911915PMC
November 2010

Vaccinations in patients with immune-mediated inflammatory diseases.

Rheumatology (Oxford) 2010 Oct 29;49(10):1815-27. Epub 2010 Jun 29.

Department of Rheumatology, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1093/rheumatology/keq183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936949PMC
October 2010

Reliability of the qualitative and semiquantitative nailfold videocapillaroscopy assessment in a systemic sclerosis cohort: a two-centre study.

Ann Rheum Dis 2010 Jun 3;69(6):1092-6. Epub 2010 May 3.

Department of Rheumatology, Ghent University Hospital, 0K12-IB, De Pintelaan 185, Ghent B-9000, Belgium.

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http://dx.doi.org/10.1136/ard.2009.115568DOI Listing
June 2010

Validation of a manual ability questionnaire in patients with systemic sclerosis.

Arthritis Rheum 2009 May;61(5):695-703

Cliniques universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium.

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http://doi.wiley.com/10.1002/art.24426
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http://dx.doi.org/10.1002/art.24426DOI Listing
May 2009

Clinical observations programme in SpA: disease parameters, treatment options and practical management issues.

Rheumatol Int 2009 Jan 26;29(3):239-50. Epub 2008 Sep 26.

Department of Rheumatology, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.

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http://dx.doi.org/10.1007/s00296-008-0714-5DOI Listing
January 2009

Effects of intra-articular corticosteroids and anti-TNF therapy on neutrophil activation in rheumatoid arthritis.

Ann Rheum Dis 2007 Aug 12;66(8):1020-5. Epub 2007 Jan 12.

Interdisciplinary Centre of Clinical Research, University of Münster, Röntgenstr. 21, D-48149 Münster, Germany.

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http://dx.doi.org/10.1136/ard.2006.061507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1954711PMC
August 2007

Spondyloarthropathies.

Authors:
Filip De Keyser

Curr Opin Rheumatol 2007 Jul;19(4):333-4

Departmrnt of Rheumatology, Ghent University, Gent, Belgium.

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https://insights.ovid.com/crossref?an=00002281-200707000-000
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http://dx.doi.org/10.1097/BOR.0b013e328186fe04DOI Listing
July 2007

Anti-TNF-alpha therapy in ankylosing spondylitis.

Cytokine 2006 Mar 3;33(5):294-8. Epub 2006 Mar 3.

Department of Rheumatology, Gent University Hospital, De Pintelaan 185, B-9000 Gent, Belgium.

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http://dx.doi.org/10.1016/j.cyto.2006.01.004DOI Listing
March 2006

Gut inflammation in the spondyloarthropathies.

Curr Rheumatol Rep 2005 Jun;7(3):188-94

Department of Rheumatology, 0K12IB, Ghent University Hospital, De Pintelaan 185, 9000 Gent, Belgium.

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June 2005

Fibrin deimination in synovial tissue is not specific for rheumatoid arthritis but commonly occurs during synovitides.

J Immunol 2005 Apr;174(8):5057-64

Laboratory of Epidermis Differentiation and Rheumatoid Autoimmunity, Unité Mixte de Recherche 5165 Centre National de la Recherche Scientifique-Toulouse III University, Institut Fédératif de Recherche 30, Toulouse, France.

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http://dx.doi.org/10.4049/jimmunol.174.8.5057DOI Listing
April 2005

Association of CD163+ macrophages and local production of soluble CD163 with decreased lymphocyte activation in spondylarthropathy synovitis.

Arthritis Rheum 2004 May;50(5):1611-23

Department of Rheumatology, 0K12IB, Ghent University Hospital, De Pintelaan 185, B-9000 Ghent, Belgium.

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http://dx.doi.org/10.1002/art.20174DOI Listing
May 2004

The histopathology of spondyloarthropathy.

Curr Mol Med 2004 Feb;4(1):1-12

Department of Rheumatology, Ghent University Hospital, Belgium.

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http://dx.doi.org/10.2174/1566524043479310DOI Listing
February 2004

Infliximab in patients who have spondyloarthropathy: clinical efficacy, safety, and biological immunomodulation.

Rheum Dis Clin North Am 2003 Aug;29(3):463-79

Department of Rheumatology, Ghent University Hospital, De Pintelaan 185, B-9000 Ghent, Belgium.

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August 2003