Publications by authors named "Fernando Pagan"

36Publications

Long-Term Safety and Clinical Effects of Nilotinib in Parkinson's Disease.

Mov Disord 2020 Nov 20. Epub 2020 Nov 20.

Translational Neurotherapeutics Program, Laboratory for Dementia and Parkinsonism, Department of Neurology, Georgetown University Medical Center, Washington, District of Columbia, USA.

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http://dx.doi.org/10.1002/mds.28389DOI Listing
November 2020

Sialorrhea in Parkinson's Disease.

Toxins (Basel) 2020 Oct 31;12(11). Epub 2020 Oct 31.

Department of Neurology, Medstar Georgetown University Hospital, 2800 Reservoir Rd., NW Washington, D.C., WA 20007, USA.

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http://dx.doi.org/10.3390/toxins12110691DOI Listing
October 2020

Can sex influence the neurocognition of language? Evidence from Parkinson's disease.

Neuropsychologia 2020 Sep 22;148:107633. Epub 2020 Sep 22.

Brain and Language Laboratory, Department of Neuroscience, Georgetown University, Washington, DC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuropsychologia.2020.107633DOI Listing
September 2020

IncobotulinumtoxinA for the Treatment of Blepharospasm in Toxin-Naïve Subjects: A Multi-Center, Double-Blind, Randomized, Placebo-Controlled Trial.

Adv Ther 2020 Oct 10;37(10):4249-4265. Epub 2020 Aug 10.

Department of Neurology, Georgetown University Hospital Pasquerilla Healthcare Center, Washington, DC, USA.

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http://dx.doi.org/10.1007/s12325-020-01427-6DOI Listing
October 2020

Discoidin Domain Receptor 1 is a therapeutic target for neurodegenerative diseases.

Hum Mol Genet 2020 Oct;29(17):2882-2898

Department of Neurology, Translational Neurotherapeutics Program, Laboratory for Dementia and Parkinsonism, Lewy Body Dementia Association, Research Center of Excellence, Georgetown University Medical Center, Washington, DC 20057, USA.

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http://dx.doi.org/10.1093/hmg/ddaa177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566445PMC
October 2020

Nilotinib Effects on Safety, Tolerability, and Biomarkers in Alzheimer's Disease.

Ann Neurol 2020 07 28;88(1):183-194. Epub 2020 May 28.

Translational Neurotherapeutics Program, Laboratory for Dementia and Parkinsonism, Department of Neurology, Georgetown University Medical Center, Washington, DC, USA.

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http://dx.doi.org/10.1002/ana.25775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383852PMC
July 2020

Safety and Efficacy of RimabotulinumtoxinB for Treatment of Sialorrhea in Adults: A Randomized Clinical Trial.

JAMA Neurol 2020 04;77(4):461-469

James J. and Joan A. Gardner Family Center for Parkinson's Disease and Movement Disorders, University of Cincinnati, Cincinnati, Ohio.

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http://dx.doi.org/10.1001/jamaneurol.2019.4565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990829PMC
April 2020

Long-term incobotulinumtoxinA treatment for chronic sialorrhea: Efficacy and safety over 64 weeks.

Parkinsonism Relat Disord 2020 01 26;70:23-30. Epub 2019 Nov 26.

Department of Otolaryngology/Head and Neck Surgery, Columbia University College of Physicians and Surgeons, New York, NY, USA; Department of Neurology, Icahn School of Medicine at Mt. Sinai, New York, NY, USA; NY Center for Voice and Swallowing Disorders, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2019.11.024DOI Listing
January 2020

Changing the treatment paradigm for Parkinson's disease psychosis with pimavanserin.

Expert Rev Clin Pharmacol 2019 Jul 13;12(7):681-691. Epub 2019 Jun 13.

e Parkinson's Disease and Movement Disorders Center of Boca Raton , Boca Raton , FL , USA.

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http://dx.doi.org/10.1080/17512433.2019.1623669DOI Listing
July 2019

SIAXI: Placebo-controlled, randomized, double-blind study of incobotulinumtoxinA for sialorrhea.

Neurology 2019 04 27;92(17):e1982-e1991. Epub 2019 Mar 27.

From the Parkinson-Klinik Ortenau (W.H.J.), Wolfach, Germany; Department of Neurology (A.F.), Faculty of Health Science, Medical University of Warsaw, Poland; Department of Otorhinolaryngology (O.M.), University Hospital Brussels, Vrije Universiteit Brussel, Belgium; Neurological Outpatient Clinic for Parkinson's Disease and Deep Brain Stimulation (C.O.), Gera, Germany; Department of Neurological-Psychiatric Nursing (J.S.), Medical University of Gdansk; Neurology Department (J.S.), St. Adalbert Hospital, Gdansk; Department of Extrapyramidal Diseases (A. Bogucki), Medical University of Łódź; Department of Neurology and Stroke Unit (S.O.), Medical University of Silesia, Katowice; Department of Neurology (M.B.), Collegium Medicum, Jagiellonian University, Krakow, Poland; Department of Neurology (F.P.), Georgetown University Hospital, Washington, DC; Merz Pharmaceuticals GmbH (B.F.-B., J.C.), Frankfurt am Main, Germany; Complete Medical Communications (C.J.C.), Glasgow, UK; Department of Otolaryngology/Head and Neck Surgery (A. Blitzer), Columbia University College of Physicians and Surgeons, New York; Department of Neurology (A. Blitzer), Icahn School of Medicine at Mt. Sinai, New York; and NY Center for Voice and Swallowing Disorders (A. Blitzer), New York, NY.

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http://dx.doi.org/10.1212/WNL.0000000000007368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511076PMC
April 2019

Pharmacokinetics and pharmacodynamics of a single dose Nilotinib in individuals with Parkinson's disease.

Pharmacol Res Perspect 2019 04 12;7(2):e00470. Epub 2019 Mar 12.

Translational Neurotherapeutics Program Laboratory for Dementia and Parkinsonism Department of Neurology Georgetown University Medical Center Washington District of Columbia.

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http://dx.doi.org/10.1002/prp2.470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412143PMC
April 2019

The diagnosis and natural history of Huntington disease.

Handb Clin Neurol 2017 ;144:63-67

Georgetown University School of Medicine, Washington, DC, United States.

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http://dx.doi.org/10.1016/B978-0-12-801893-4.00005-5DOI Listing
March 2018

Optimizing extended-release carbidopa/levodopa in Parkinson disease: Consensus on conversion from standard therapy.

Neurol Clin Pract 2017 Feb;7(1):86-93

University of Cincinnati (AJE), OH; Georgetown University Hospital (FLP), Washington, DC; Case Western Reserve University (BLW), Cleveland, OH; Medical College of Georgia (JCM), Augusta University; University of Toledo College of Medicine (LWE), OH; Columbia University (CHW), New York, NY; Evergreen Hospital Medical Center (PA), Kirkland, WA; Parkinson's Institute and Clinical Center (RD), Sunnyvale, CA; Methodist Neurological Institute (WGO), Houston, TX; The Movement Disorder Clinic of Oklahoma (KJK), Tulsa; and Coastal Neurological Medical Group, Inc. (DES), La Jolla, CA.

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http://dx.doi.org/10.1212/CPJ.0000000000000316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310207PMC
February 2017

Apomorphine Subcutaneous Injection for the Management of Morning Akinesia in Parkinson's Disease.

Mov Disord Clin Pract 2017 Jan-Feb;4(1):78-83. Epub 2016 May 25.

Georgetown University Medical Center Washington DC USA.

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http://dx.doi.org/10.1002/mdc3.12350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298032PMC
May 2016

A Screening Tool to Identify Spasticity in Need of Treatment.

Am J Phys Med Rehabil 2017 May;96(5):315-320

From the Johns Hopkins University, Baltimore, Maryland (RDZ); McGill University, Montreal, Quebec, Canada (THW); Department of Rehabilitation Sciences, University of Cincinnati, Cincinnati, Ohio (KD); CHU Dinant Godinne-UcL Namur, Department of Physical Medicine and Rehabilitation, Yvoir, Belgium (TD); Epworth Healthcare and Monash University, Victoria, Australia (JHO); Indiana University School of Medicine, Indianapolis, Indiana (SJD); School of Medicine and Rehabilitation and Orthopaedic Institute, University of Maryland, Baltimore, Maryland (MAD); Island Neurological, a division of ProHEALTH Care Associates, LLP, Plainview, New York (JK); Department of Neurology, Georgetown University Hospital, Washington, DC (FLP); Endpoint Outcomes, Boston, Massachusetts (CJE); Global Health Outcomes Strategy and Research, Allergan plc, Irvine, California (PJG); and Department of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio (BMK).

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http://dx.doi.org/10.1097/PHM.0000000000000605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404395PMC
May 2017

Nilotinib Effects in Parkinson's disease and Dementia with Lewy bodies.

J Parkinsons Dis 2016 07;6(3):503-17

Department of Neurology, Laboratory for Dementia and Parkinsonism, National Parkinson's Foundation Center for Excellence, Translational Neurotherapeutics Program. Georgetown University Medical Center, Washington, DC, USA.

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http://dx.doi.org/10.3233/JPD-160867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008228PMC
July 2016

Rasagiline for mild cognitive impairment in Parkinson's disease: A placebo-controlled trial.

Mov Disord 2016 05 31;31(5):709-14. Epub 2016 Mar 31.

Teva Pharmaceuticals, Overland Park, Kansas, USA.

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http://dx.doi.org/10.1002/mds.26617DOI Listing
May 2016

Patient considerations in the treatment of cervical dystonia: focus on botulinum toxin type A.

Patient Prefer Adherence 2015 2;9:725-31. Epub 2015 Jun 2.

Department of Neurology, Movement Disorders and Neurorestoration Division, Georgetown University Hospital, Washington, DC, USA.

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http://dx.doi.org/10.2147/PPA.S75459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459632PMC
June 2015

Tyrosine Kinase Inhibition Regulates Early Systemic Immune Changes and Modulates the Neuroimmune Response in α-Synucleinopathy.

J Clin Cell Immunol 2014 Sep;5:259

Department of Neuroscience, Laboratory for Dementia and Parkinsonism, Georgetown University Medical Center, Washington D.C., 20007, USA ; Neurorestoration Group, Movement Disorders Program, National Parkinson Foundation Center of Excellence, Georgetown University Hospital, Washington D.C., 20007, USA.

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http://dx.doi.org/10.4172/2155-9899.1000259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308054PMC
September 2014

An update on the use of botulinum toxin therapy in Parkinson's disease.

Curr Neurol Neurosci Rep 2015 Jan;15(1):511

Movement Disorders Division, Department of Neurology, Georgetown University Hospital, 3900 Reservoir Rd, NW, 7 PHC, Washington, DC, 20007, USA,

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http://dx.doi.org/10.1007/s11910-014-0511-3DOI Listing
January 2015

Improving outcomes through early diagnosis of Parkinson's disease.

Authors:
Fernando L Pagan

Am J Manag Care 2012 Sep;18(7 Suppl):S176-82

Movement Disorders Program, Department of Neurology, Georgetown University Hospital, Washington, DC, USA.

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September 2012

A guide to dosing in the treatment of cervical dystonia and blepharospasm with Xeomin®: a new botulinum neurotoxin A.

Parkinsonism Relat Disord 2012 Jun 9;18(5):441-5. Epub 2012 Mar 9.

Georgetown University Hospital, GUH 7PHC, 3800 Reservoir Road, NW, Washington, DC 20007, USA.

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http://dx.doi.org/10.1016/j.parkreldis.2012.02.008DOI Listing
June 2012

CXCR4 and CXCL12 expression is increased in the nigro-striatal system of Parkinson's disease.

Neurotox Res 2009 Oct 24;16(3):318-28. Epub 2009 Jun 24.

Department of Neuroscience, Georgetown University Medical Center, Research Building, Room EP04, 3970 Reservoir Rd, NW, Box 571464, Washington, DC 20057, USA.

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http://dx.doi.org/10.1007/s12640-009-9076-3DOI Listing
October 2009

Safety of MRI in patients with implanted deep brain stimulation devices.

Neuroimage 2009 Aug 17;47 Suppl 2:T53-7. Epub 2009 Apr 17.

Department of Neurology, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1016/j.neuroimage.2009.04.044DOI Listing
August 2009

Involvement of insula and cingulate cortices in control and suppression of natural urges.

Cereb Cortex 2009 Jan 9;19(1):218-23. Epub 2008 May 9.

Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/cercor/bhn074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638741PMC
January 2009

Evaluation of essential tremor with multi-voxel magnetic resonance spectroscopy.

Neurology 2003 Apr;60(8):1344-7

Medical Neurology Branch, National Institutes of Health, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892-1428, USA.

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http://dx.doi.org/10.1212/01.wnl.0000065885.15875.0dDOI Listing
April 2003