Publications by authors named "Fernando O Martinez"

44Publications

Monocyte activation in systemic Covid-19 infection: Assay and rationale.

EBioMedicine 2020 Sep 30;59:102964. Epub 2020 Aug 30.

Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan City, Taiwan; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2020.102964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456455PMC
September 2020

Foam Cells Control Infection.

Front Microbiol 2020 9;11:1394. Epub 2020 Jul 9.

Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom.

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http://dx.doi.org/10.3389/fmicb.2020.01394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381311PMC
July 2020

Epicardial cell shape and maturation are regulated by Wt1 via transcriptional control of .

Development 2019 10 17;146(20). Epub 2019 Oct 17.

Celltec-UB, Department of Cell Biology, Physiology and Immunology, Faculty of Biology, University of Barcelona, Barcelona 08028, Spain

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http://dx.doi.org/10.1242/dev.178723DOI Listing
October 2019

Lactobacilli Isolated From Wild Boar () Antagonize Bacille Calmette-Guerin (BCG) in a Species-Dependent Manner.

Front Microbiol 2019 30;10:1663. Epub 2019 Jul 30.

Department of Nutritional Sciences, School of Biosciences and Medicine, University of Surrey, Guildford, United Kingdom.

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http://dx.doi.org/10.3389/fmicb.2019.01663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683848PMC
July 2019

The Elusive Role of Placental Macrophages: The Hofbauer Cell.

J Innate Immun 2019 10;11(6):447-456. Epub 2019 Apr 10.

Institute of Infectious Disease and Molecular Medicine, Division of Immunology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa,

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http://dx.doi.org/10.1159/000497416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758944PMC
July 2020

Oxidative stress and macrophages: driving forces behind exacerbations of asthma and chronic obstructive pulmonary disease?

Am J Physiol Lung Cell Mol Physiol 2019 02 6;316(2):L369-L384. Epub 2018 Dec 6.

Department of Pharmacokinetics, Toxicology, and Targeting, Groningen Research Institute for Pharmacy, University of Groningen , Groningen , The Netherlands.

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http://dx.doi.org/10.1152/ajplung.00456.2018DOI Listing
February 2019

Macrophage Heterogeneity in the Immunopathogenesis of Tuberculosis.

Front Microbiol 2018 23;9:1028. Epub 2018 May 23.

Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.

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http://dx.doi.org/10.3389/fmicb.2018.01028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974223PMC
May 2018

Persistent stromal fibroblast activation is present in chronic tendinopathy.

Arthritis Res Ther 2017 Jan 25;19(1):16. Epub 2017 Jan 25.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Nuffield Orthopaedic Centre, Headington, OX3 7LD, UK.

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http://arthritis-research.biomedcentral.com/articles/10.1186
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http://dx.doi.org/10.1186/s13075-016-1218-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264298PMC
January 2017

Multinucleated Giant Cells Are Specialized for Complement-Mediated Phagocytosis and Large Target Destruction.

Cell Rep 2015 Dec 25;13(9):1937-48. Epub 2015 Nov 25.

Institute for Medical Microbiology, Immunology and Hygiene, Technische Universität München, 81675 Munich, Germany.

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http://dx.doi.org/10.1016/j.celrep.2015.10.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675895PMC
December 2015

Inflammation activation and resolution in human tendon disease.

Sci Transl Med 2015 Oct;7(311):311ra173

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Nuffield Orthopaedic Centre, Headington OX3 7LD, UK. NIHR Oxford Biomedical Research Unit, Botnar Research Centre, University of Oxford, Oxford OX3 7LD, UK.

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http://dx.doi.org/10.1126/scitranslmed.aac4269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883654PMC
October 2015

G3BP1 restricts HIV-1 replication in macrophages and T-cells by sequestering viral RNA.

Virology 2015 Dec 29;486:94-104. Epub 2015 Sep 29.

Department of Experimental Immunology, Sanquin Research, Landsteiner Laboratory, and Center for Infectious Diseases and Immunity Amsterdam (CINIMA), Academic Medical Center of the University of Amsterdam, Amsterdam 1105AZ, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2015.09.007DOI Listing
December 2015

CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses.

Proc Natl Acad Sci U S A 2015 Aug 10;112(34):10768-73. Epub 2015 Aug 10.

Botnar Research Institute, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, University of Oxford, Oxford OX3 7LD, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1501956112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553799PMC
August 2015

Cholesterol loading reprograms the microRNA-143/145-myocardin axis to convert aortic smooth muscle cells to a dysfunctional macrophage-like phenotype.

Arterioscler Thromb Vasc Biol 2015 Mar 8;35(3):535-46. Epub 2015 Jan 8.

From the Marc and Ruti Bell Program in Vascular Biology, Division of Cardiology, Department of Medicine, NYU School of Medicine, New York (Y.V., H.N., M.O., N.S., C.P.C., K.J.M., E.A.F.); Center for Cardiovascular Sciences, Albany Medical College, NY (X.L.); Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, United Kingdom (F.O.M.); Department of Biomedical Sciences, Oregon State University, Corvallis (S.A.R.); and Department of Medicine, Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, NY (J.M.M.).

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http://dx.doi.org/10.1161/ATVBAHA.114.304029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344402PMC
March 2015

The evolution of our understanding of macrophages and translation of findings toward the clinic.

Expert Rev Clin Immunol 2015 Jan 1;11(1):5-13. Epub 2014 Dec 1.

Botnar Research Centre, University of Oxford, Windmill Road, Oxford, OX3 7LD, UK.

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http://dx.doi.org/10.1586/1744666X.2015.985658DOI Listing
January 2015

Hepatic Localization of Macrophage Phenotypes during Fibrogenesis and Resolution of Fibrosis in Mice and Humans.

Front Immunol 2014 8;5:430. Epub 2014 Sep 8.

Department of Pharmacokinetics, Toxicology and Targeting, University of Groningen , Groningen , Netherlands.

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http://dx.doi.org/10.3389/fimmu.2014.00430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157549PMC
September 2014

The M1 and M2 paradigm of macrophage activation: time for reassessment.

F1000Prime Rep 2014 3;6:13. Epub 2014 Mar 3.

Sir William Dunn School of Pathology, University of Oxford South Parks Road, Oxford, OX1 3RE UK.

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http://dx.doi.org/10.12703/P6-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944738PMC
June 2014

Chronic exposure to glucocorticoids shapes gene expression and modulates innate and adaptive activation pathways in macrophages with distinct changes in leukocyte attraction.

J Immunol 2014 Feb 6;192(3):1196-208. Epub 2014 Jan 6.

Department of Experimental Immunology, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands;

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http://dx.doi.org/10.4049/jimmunol.1302138DOI Listing
February 2014

WT1 regulates the expression of inhibitory chemokines during heart development.

Hum Mol Genet 2013 Dec 29;22(25):5083-95. Epub 2013 Jul 29.

MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Edinburgh EH4 2XU, UK.

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http://dx.doi.org/10.1093/hmg/ddt358DOI Listing
December 2013

Analysis of gene expression and gene silencing in human macrophages.

Curr Protoc Immunol 2012 Feb;Chapter 14:Unit 14.28.1-23

Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1002/0471142735.im1428s96DOI Listing
February 2012

Regulators of macrophage activation.

Eur J Immunol 2011 Jun 24;41(6):1531-4. Epub 2011 May 24.

Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1002/eji.201141670DOI Listing
June 2011

Alternative activation of macrophages: mechanism and functions.

Immunity 2010 May;32(5):593-604

Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK.

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http://dx.doi.org/10.1016/j.immuni.2010.05.007DOI Listing
May 2010

The transcriptome of human monocyte subsets begins to emerge.

J Biol 2009 23;8(11):99. Epub 2009 Dec 23.

Sir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK.

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http://dx.doi.org/10.1186/jbiol206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804287PMC
September 2013

Alternative activation of macrophages: an immunologic functional perspective.

Annu Rev Immunol 2009 ;27:451-83

Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom.

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http://dx.doi.org/10.1146/annurev.immunol.021908.132532DOI Listing
May 2009

Stage-specific sampling by pattern recognition receptors during Candida albicans phagocytosis.

PLoS Pathog 2008 Nov 28;4(11):e1000218. Epub 2008 Nov 28.

Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1371/journal.ppat.1000218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583056PMC
November 2008

Homogeneous monocytes and macrophages from human embryonic stem cells following coculture-free differentiation in M-CSF and IL-3.

Exp Hematol 2008 Sep 11;36(9):1167-75. Epub 2008 Jun 11.

Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, UK.

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http://dx.doi.org/10.1016/j.exphem.2008.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635571PMC
September 2008

Analysis of global gene expression profiles activated by chemoattractant receptors.

Methods Mol Biol 2006 ;332:313-29

Institute of General Pathology, University of Milan, Italy.

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http://dx.doi.org/10.1385/1-59745-048-0:311DOI Listing
August 2006

Gene expression profile activated by the chemokine CCL5/RANTES in human neuronal cells.

J Neurosci Res 2004 Nov;78(3):371-82

Division of Pharmacology, Department of Biomedical Sciences and Biotechnologies, Brescia University School of Medicine, viale Europa 11, 25123 Brescia, Italy.

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http://dx.doi.org/10.1002/jnr.20250DOI Listing
November 2004

IL-8 induces a specific transcriptional profile in human neutrophils: synergism with LPS for IL-1 production.

Eur J Immunol 2004 Aug;34(8):2286-92

Centro di Eccellenza per l'Innovazione Diagnostica e Terapeutica, Institute of General Pathology, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1002/eji.200324481DOI Listing
August 2004

Tuning of innate immunity and polarized responses by decoy receptors.

Int Arch Allergy Immunol 2003 Oct;132(2):109-15

Department of Immunology and Cell Biology, Istituto di Ricerche Farmacologiche Mario Negri, Faculty of Medicine, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1159/000073711DOI Listing
October 2003