Ferhaan Ahmad

Ferhaan Ahmad

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Ferhaan Ahmad

Ferhaan Ahmad

Publications by authors named "Ferhaan Ahmad"

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Cardiac sodium-dependent glucose cotransporter 1 is a novel mediator of ischaemia/reperfusion injury.

Cardiovasc Res 2019 Sep;115(11):1646-1658

Division of Cardiovascular Medicine, Department of Internal Medicine, Carver College of Medicine and Abboud Cardiovascular Research Center, University of Iowa, 100 Newton Road, 1191D ML, Iowa City, IA, USA.

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https://academic.oup.com/cardiovascres/advance-article/doi/1
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http://dx.doi.org/10.1093/cvr/cvz037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704393PMC
September 2019

Patient with a PRKAG2 mutation who developed Immunoglobulin A nephropathy: a case report.

Eur Heart J Case Rep 2019 Jun;3(2)

Department of Pathology, University of Iowa Hospitals, 200 Hawkins Drive, 4426JCP, Iowa City, IA, USA.

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http://dx.doi.org/10.1093/ehjcr/ytz038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601182PMC
June 2019

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.

Authors:
Christopher J Rhodes Ken Batai Marta Bleda Matthias Haimel Laura Southgate Marine Germain Michael W Pauciulo Charaka Hadinnapola Jurjan Aman Barbara Girerd Amit Arora Jo Knight Ken B Hanscombe Jason H Karnes Marika Kaakinen Henning Gall Anna Ulrich Lars Harbaum Inês Cebola Jorge Ferrer Katie Lutz Emilia M Swietlik Ferhaan Ahmad Philippe Amouyel Stephen L Archer Rahul Argula Eric D Austin David Badesch Sahil Bakshi Christopher Barnett Raymond Benza Nitin Bhatt Harm J Bogaard Charles D Burger Murali Chakinala Colin Church John G Coghlan Robin Condliffe Paul A Corris Cesare Danesino Stéphanie Debette C Gregory Elliott Jean Elwing Melanie Eyries Terry Fortin Andre Franke Robert P Frantz Adaani Frost Joe G N Garcia Stefano Ghio Hossein-Ardeschir Ghofrani J Simon R Gibbs John Harley Hua He Nicholas S Hill Russel Hirsch Arjan C Houweling Luke S Howard Dunbar Ivy David G Kiely James Klinger Gabor Kovacs Tim Lahm Matthias Laudes Rajiv D Machado Robert V MacKenzie Ross Keith Marsolo Lisa J Martin Shahin Moledina David Montani Steven D Nathan Michael Newnham Andrea Olschewski Horst Olschewski Ronald J Oudiz Willem H Ouwehand Andrew J Peacock Joanna Pepke-Zaba Zia Rehman Ivan Robbins Dan M Roden Erika B Rosenzweig Ghulam Saydain Laura Scelsi Robert Schilz Werner Seeger Christian M Shaffer Robert W Simms Marc Simon Olivier Sitbon Jay Suntharalingam Haiyang Tang Alexander Y Tchourbanov Thenappan Thenappan Fernando Torres Mark R Toshner Carmen M Treacy Anton Vonk Noordegraaf Quinten Waisfisz Anna K Walsworth Robert E Walter John Wharton R James White Jeffrey Wilt Stephen J Wort Delphine Yung Allan Lawrie Marc Humbert Florent Soubrier David-Alexandre Trégouët Inga Prokopenko Richard Kittles Stefan Gräf William C Nichols Richard C Trembath Ankit A Desai Nicholas W Morrell Martin R Wilkins

Lancet Respir Med 2019 Mar 5;7(3):227-238. Epub 2018 Dec 5.

Department of Medicine, Imperial College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(18)30409-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391516PMC
March 2019

Heterozygotes Are at Increased Risk of Respiratory Infections: A Population-Based Study.

Open Forum Infect Dis 2018 Nov 1;5(11):ofy219. Epub 2018 Nov 1.

Department of Internal Medicine, University of Iowa, Iowa City, Iowa.

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http://dx.doi.org/10.1093/ofid/ofy219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210382PMC
November 2018

SGLT1 and Sweet Genetic Insights Into Cardiometabolic Risk.

J Am Coll Cardiol 2018 10;72(15):1774-1777

Division of Cardiovascular Medicine, Department of Internal Medicine, and Abboud Cardiovascular Research Center, University of Iowa, Iowa City, Iowa; Stead Family Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa.

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https://linkinghub.elsevier.com/retrieve/pii/S07351097183692
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http://dx.doi.org/10.1016/j.jacc.2018.07.060DOI Listing
October 2018

S100A12 as a marker of worse cardiac output and mortality in pulmonary hypertension.

Respirology 2018 08 2;23(8):771-779. Epub 2018 Apr 2.

Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1111/resp.13302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047907PMC
August 2018

Female sex is associated with worse prognosis in patients with hypertrophic cardiomyopathy in China.

PLoS One 2014 21;9(7):e102969. Epub 2014 Jul 21.

Sino-German Laboratory for Molecular Medicine, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Department of Cardiovascular Internal Medicine, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Hypertension Center, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0102969PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105411PMC
November 2015

Malignant effects of multiple rare variants in sarcomere genes on the prognosis of patients with hypertrophic cardiomyopathy.

Eur J Heart Fail 2014 Sep 31;16(9):950-7. Epub 2014 Jul 31.

State Key Laboratory of Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1002/ejhf.144DOI Listing
September 2014

Transgenic knockdown of cardiac sodium/glucose cotransporter 1 (SGLT1) attenuates PRKAG2 cardiomyopathy, whereas transgenic overexpression of cardiac SGLT1 causes pathologic hypertrophy and dysfunction in mice.

J Am Heart Assoc 2014 Aug 4;3(4). Epub 2014 Aug 4.

UPMC Heart and Vascular Institute and Division of Cardiology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA (M.R., R.K.S., S.A., S.J.L., D.W., X.Y.N.H., F.A.) Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA (F.A.) Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA (F.A.).

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http://dx.doi.org/10.1161/JAHA.114.000899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310371PMC
August 2014

The genomic complexity underlying pulmonary arterial hypertension: from mendel to networks.

Am J Respir Crit Care Med 2014 May;189(10):1152-4

1 Illumina, Inc. Santa Clara, California.

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http://dx.doi.org/10.1164/rccm.201403-0556EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225853PMC
May 2014

Rare variants in genes encoding MuRF1 and MuRF2 are modifiers of hypertrophic cardiomyopathy.

Int J Mol Sci 2014 May 26;15(6):9302-13. Epub 2014 May 26.

State Key Laboratory of Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.

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http://dx.doi.org/10.3390/ijms15069302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100095PMC
May 2014

Autosomal recessive transmission of MYBPC3 mutation results in malignant phenotype of hypertrophic cardiomyopathy.

PLoS One 2013 28;8(6):e67087. Epub 2013 Jun 28.

Department of Cardiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0067087PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695947PMC
January 2014

Cellular, pharmacological, and biophysical evaluation of explanted lungs from a patient with sickle cell disease and severe pulmonary arterial hypertension.

Pulm Circ 2013 Dec;3(4):936-51

Vascular Medicine Institute of the University of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA ; Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1086/674754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070844PMC
December 2013

High mobility group box 1 contributes to the pathogenesis of experimental pulmonary hypertension via activation of Toll-like receptor 4.

Mol Med 2013 Feb 8;18:1509-18. Epub 2013 Feb 8.

Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, United States of America.

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http://dx.doi.org/10.2119/molmed.2012.00283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576475PMC
February 2013

Early treatment with fumagillin, an inhibitor of methionine aminopeptidase-2, prevents Pulmonary Hypertension in monocrotaline-injured rats.

PLoS One 2012 11;7(4):e35388. Epub 2012 Apr 11.

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine and the Dorothy P and Richard P Simmons Center for Interstitial Lung Disease, Pittsburgh, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035388PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324555PMC
August 2012

Functional effects of the TMEM43 Ser358Leu mutation in the pathogenesis of arrhythmogenic right ventricular cardiomyopathy.

BMC Med Genet 2012 Mar 29;13:21. Epub 2012 Mar 29.

UPMC Heart and Vascular Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1186/1471-2350-13-21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352248PMC
March 2012

Midterm outcomes of off-pump and on-pump coronary artery revascularization in renal transplant recipients.

J Card Surg 2011 Nov 14;26(6):591-5. Epub 2011 Oct 14.

Department of Cardiothoracic Surgery, Thomas E. Starzl Transplantation Institute, and Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1111/j.1540-8191.2011.01327.xDOI Listing
November 2011

Somatic mutations in pulmonary arterial hypertension: primary or secondary events?

Am J Respir Crit Care Med 2010 Nov;182(9):1094-6

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http://dx.doi.org/10.1164/rccm.201007-1147EDDOI Listing
November 2010

Activation of cardiac hypertrophic signaling pathways in a transgenic mouse with the human PRKAG2 Thr400Asn mutation.

Biochim Biophys Acta 2010 Feb 11;1802(2):284-91. Epub 2009 Dec 11.

Cardiovascular Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213-2582, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S092544390900294
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http://dx.doi.org/10.1016/j.bbadis.2009.12.001DOI Listing
February 2010

SGLT1 is a novel cardiac glucose transporter that is perturbed in disease states.

Cardiovasc Res 2009 Oct 9;84(1):111-8. Epub 2009 Jun 9.

Cardiovascular Institute, University of Pittsburgh, 200 Lothrop Street, Suite S-558, Pittsburgh, PA 15213-2582, USA.

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http://dx.doi.org/10.1093/cvr/cvp190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741348PMC
October 2009

E2F3 plays an essential role in cardiac development and function.

Cell Cycle 2008 Dec 22;7(23):3775-80. Epub 2008 Dec 22.

David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

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http://www.tandfonline.com/doi/abs/10.4161/cc.7.23.7240
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723769PMC
http://dx.doi.org/10.4161/cc.7.23.7240DOI Listing
December 2008

A PRKAG2 mutation causes biphasic changes in myocardial AMPK activity and does not protect against ischemia.

Biochem Biophys Res Commun 2007 Aug 19;360(2):381-7. Epub 2007 Jun 19.

Cardiovascular Institute, Department of Medicine, University of Pittsburgh, S558, Pittsburgh, PA 15213, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0701292
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http://dx.doi.org/10.1016/j.bbrc.2007.06.067DOI Listing
August 2007

Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function.

Proc Natl Acad Sci U S A 2006 Sep 18;103(39):14525-30. Epub 2006 Sep 18.

Department of Genetics and Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.0606383103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1599993PMC
September 2006

The genetic basis for cardiac remodeling.

Annu Rev Genomics Hum Genet 2005 ;6:185-216

Cardiovascular Institute and Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1146/annurev.genom.6.080604.162132DOI Listing
December 2005

Functional role of AMP-activated protein kinase in the heart during exercise.

FEBS Lett 2005 Apr;579(10):2045-50

Research Division, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA.

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http://dx.doi.org/10.1016/j.febslet.2005.02.052DOI Listing
April 2005

Consequences of pressure overload on sarcomere protein mutation-induced hypertrophic cardiomyopathy.

Circulation 2003 Sep 18;108(9):1133-8. Epub 2003 Aug 18.

Department of Genetics, Harvard Medical School and Howard Hughes Medical Institute, Boston, Mass 02115, USA.

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http://dx.doi.org/10.1161/01.CIR.0000086469.85750.48DOI Listing
September 2003

The molecular genetics of arrhythmogenic right ventricular dysplasia-cardiomyopathy.

Authors:
Ferhaan Ahmad

Clin Invest Med 2003 Aug;26(4):167-78

Department of Genetics, Harvard Medical School, Howard Hughes Medical Institute, Boston, Mass 02115, USA.

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August 2003

IL-12 is required for differentiation of pathogenic CD8+ T cell effectors that cause myocarditis.

J Clin Invest 2003 Mar;111(5):671-80

Immunology Research Division, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1172/JCI16867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC151896PMC
March 2003

Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban.

Science 2003 Feb;299(5611):1410-3

Department of Genetics, Harvard Medical School and Howard Hughes Medical Institute, 200 Longwood Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1126/science.1081578DOI Listing
February 2003