Fengwu Li

Fengwu Li

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Fengwu Li

Fengwu Li

Publications by authors named "Fengwu Li"

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Reduced Apoptotic Injury by Phenothiazine in Ischemic Stroke through the NOX-Akt/PKC Pathway.

Brain Sci 2019 Dec 15;9(12). Epub 2019 Dec 15.

Department of Neurosurgery, Wayne State University School of Medicine, Detroit, MI 48201, USA.

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http://dx.doi.org/10.3390/brainsci9120378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955743PMC
December 2019

Retinoids Enhance the Expression of Cathelicidin Antimicrobial Peptide during Reactive Dermal Adipogenesis.

J Immunol 2019 Sep 16;203(6):1589-1597. Epub 2019 Aug 16.

Department of Dermatology, University of California, San Diego, La Jolla, CA 92093; and

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http://dx.doi.org/10.4049/jimmunol.1900520DOI Listing
September 2019

Phenothiazines Enhance the Hypothermic Preservation of Liver Grafts: A Pilot in Vitro Study.

Cell Transplant 2019 03 22;28(3):318-327. Epub 2019 Jan 22.

3 Department of Neurosurgery, Wayne State University School of Medicine, Detroit, MI, USA.

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http://dx.doi.org/10.1177/0963689718824559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425111PMC
March 2019

Therapeutic Target and Cell-signal Communication of Chlorpromazine and Promethazine in Attenuating Blood-Brain Barrier Disruption after Ischemic Stroke.

Cell Transplant 2019 02 20;28(2):145-156. Epub 2018 Dec 20.

1 China-America Institute of Neuroscience, Luhe Hospital, Capital Medical University, Beijing, China.

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http://dx.doi.org/10.1177/0963689718819443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362522PMC
February 2019

Age-Related Loss of Innate Immune Antimicrobial Function of Dermal Fat Is Mediated by Transforming Growth Factor Beta.

Immunity 2019 01 26;50(1):121-136.e5. Epub 2018 Dec 26.

Department of Dermatology, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.11.003DOI Listing
January 2019

Artificial Hibernation by Phenothiazines: A Potential Neuroprotective Therapy Against Cerebral Inflammation in Stroke.

Curr Neurovasc Res 2019 ;16(3):232-240

Department of Neurosurgery, Wayne State University School of Medicine, Detroit, Michigan, MI, United States.

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http://dx.doi.org/10.2174/1567202616666190624122727DOI Listing
January 2019

Omega-3 fatty acid supplement reduces activation of NADPH oxidase in intracranial atherosclerosis stenosis.

Neurol Res 2018 Jun 24;40(6):499-507. Epub 2018 Mar 24.

a China-America Institute of Neuroscience, Beijing Luhe Hospital , Capital Medical University , Beijing , China.

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http://dx.doi.org/10.1080/01616412.2018.1451290DOI Listing
June 2018

Splenectomy Fails to Provide Long-Term Protection Against Ischemic Stroke.

Aging Dis 2018 Jun 1;9(3):467-479. Epub 2018 Jun 1.

1China-America Institute of Neuroscience, Beijing Luhe Hospital, Capital Medical University, Beijing, China.

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http://dx.doi.org/10.14336/AD.2018.0130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988601PMC
June 2018

Splenic responses play an important role in remote ischemic preconditioning-mediated neuroprotection against stroke.

J Neuroinflammation 2018 May 28;15(1):167. Epub 2018 May 28.

China-America Institute of Neuroscience, Beijing Luhe Hospital, Capital Medical University, Beijing, 101100, China.

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http://dx.doi.org/10.1186/s12974-018-1190-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972448PMC
May 2018

PM2.5 inhalation induces intracranial atherosclerosis which may be ameliorated by omega 3 fatty acids.

Oncotarget 2018 Jan 16;9(3):3765-3778. Epub 2017 Dec 16.

China-America Institute of Neuroscience, Beijing Luhe Hospital, Capital Medical University, Tongzhou Qu, China.

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http://dx.doi.org/10.18632/oncotarget.23347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790498PMC
January 2018

Neuroprotection by Chlorpromazine and Promethazine in Severe Transient and Permanent Ischemic Stroke.

Mol Neurobiol 2017 Dec 28;54(10):8140-8150. Epub 2016 Nov 28.

China-America Institute of Neuroscience, Beijing Luhe Hospital, Capital Medical University, Beijing, 101100, China.

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http://dx.doi.org/10.1007/s12035-016-0280-xDOI Listing
December 2017

Erratum to: Neuroprotection by Chlorpromazine and Promethazine in Severe Transient and Permanent Ischemic Stroke.

Mol Neurobiol 2017 12;54(10):8151

China-America Institute of Neuroscience, Beijing Luhe Hospital, Capital Medical University, Beijing, 101100, China.

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http://link.springer.com/10.1007/s12035-017-0656-6
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http://dx.doi.org/10.1007/s12035-017-0656-6DOI Listing
December 2017

Bioactive compounds of Shuang-Huang-Lian prescription and an insight into its binding mechanism by β -adrenoceptor chromatography coupled with site-directed molecular docking.

J Sep Sci 2017 Nov 27;40(22):4357-4365. Epub 2017 Oct 27.

Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an, China.

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http://dx.doi.org/10.1002/jssc.201700522DOI Listing
November 2017

Frequencies of circulating B- and T-lymphocytes as indicators for stroke outcomes.

Neuropsychiatr Dis Treat 2017 3;13:2509-2518. Epub 2017 Oct 3.

Department of Neurology, China-America Institute of Neuroscience.

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http://dx.doi.org/10.2147/NDT.S148073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633294PMC
October 2017

Exacerbation of Brain Injury by Post-Stroke Exercise Is Contingent Upon Exercise Initiation Timing.

Front Cell Neurosci 2017 5;11:311. Epub 2017 Oct 5.

Department of Neurology, Luhe Hospital, Capital Medical University, Beijing, China.

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http://dx.doi.org/10.3389/fncel.2017.00311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633611PMC
October 2017

Isolation and Culture of Primary Mouse Keratinocytes from Neonatal and Adult Mouse Skin.

J Vis Exp 2017 07 14(125). Epub 2017 Jul 14.

Department of Dermatology, School of Medicine, UC San Diego;

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http://dx.doi.org/10.3791/56027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612483PMC
July 2017

Exercise rehabilitation immediately following ischemic stroke exacerbates inflammatory injury.

Neurol Res 2017 Jun 17;39(6):530-537. Epub 2017 Apr 17.

a China-America Institute of Neuroscience, Department of Neurology , Luhe Hospital, Capital Medical University , Beijing , China.

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http://dx.doi.org/10.1080/01616412.2017.1315882DOI Listing
June 2017

Enhanced apoptosis from early physical exercise rehabilitation following ischemic stroke.

J Neurosci Res 2017 04 30;95(4):1017-1024. Epub 2016 Aug 30.

China-America Institute of Neuroscience, Department of Neurology, Beijing Luhe Hospital, Capital Medical University, Beijing, China.

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http://dx.doi.org/10.1002/jnr.23890DOI Listing
April 2017

New Developments in the Pathophysiology, Workup, and Diagnosis of Dural Venous Sinus Thrombosis (DVST) and a Systematic Review of Endovascular Treatments.

Aging Dis 2017 Apr 1;8(2):136-148. Epub 2017 Apr 1.

3 Department of Neurosurgery, Wayne State University School of Medicine, Detroit, MI 48201, USA.

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http://dx.doi.org/10.14336/AD.2016.0915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362174PMC
April 2017

NOX Activation by Subunit Interaction and Underlying Mechanisms in Disease.

Front Cell Neurosci 2016 10;10:301. Epub 2017 Jan 10.

Department of Neurosurgery, Wayne State University School of MedicineDetroit, MI, USA; China-America Institute of Neuroscience, Beijing Luhe Hospital, Capital Medical UniversityBeijing, China.

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http://dx.doi.org/10.3389/fncel.2016.00301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222855PMC
January 2017

Early rehabilitation aggravates brain damage after stroke via enhanced activation of nicotinamide adenine dinucleotide phosphate oxidase (NOX).

Brain Res 2016 10 2;1648(Pt A):266-276. Epub 2016 Aug 2.

China-America Institute of Neuroscience, Beijing Luhe Hospital, Capital Medical University, China; Department of Neurosurgery, Wayne State University School of Medicine, Detroit, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2016.08.001DOI Listing
October 2016

Omega-3 fatty acid supplement prevents development of intracranial atherosclerosis.

Neuroscience 2016 Oct 11;334:226-235. Epub 2016 Aug 11.

China-America Institute of Neuroscience, Beijing Luhe Hospital, Capital Medical University, China; Department of Neurosurgery, Wayne State University School of Medicine, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuroscience.2016.08.013DOI Listing
October 2016

A new clinically relevant model for intracranial atherosclerosis in rats.

Neurol Res 2016 Sep 23;38(9):817-22. Epub 2016 Jul 23.

a China-America Institute of Neuroscience , Beijing Luhe Hospital, Capital Medical University , Beijing , China.

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http://dx.doi.org/10.1080/01616412.2016.1211232DOI Listing
September 2016

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Authors:
Wesley C Van Voorhis John H Adams Roberto Adelfio Vida Ahyong Myles H Akabas Pietro Alano Aintzane Alday Yesmalie Alemán Resto Aishah Alsibaee Ainhoa Alzualde Katherine T Andrews Simon V Avery Vicky M Avery Lawrence Ayong Mark Baker Stephen Baker Choukri Ben Mamoun Sangeeta Bhatia Quentin Bickle Lotfi Bounaadja Tana Bowling Jürgen Bosch Lauren E Boucher Fabrice F Boyom Jose Brea Marian Brennan Audrey Burton Conor R Caffrey Grazia Camarda Manuela Carrasquilla Dee Carter Maria Belen Cassera Ken Chih-Chien Cheng Worathad Chindaudomsate Anthony Chubb Beatrice L Colon Daisy D Colón-López Yolanda Corbett Gregory J Crowther Noemi Cowan Sarah D'Alessandro Na Le Dang Michael Delves Joseph L DeRisi Alan Y Du Sandra Duffy Shimaa Abd El-Salam El-Sayed Michael T Ferdig José A Fernández Robledo David A Fidock Isabelle Florent Patrick V T Fokou Ani Galstian Francisco Javier Gamo Suzanne Gokool Ben Gold Todd Golub Gregory M Goldgof Rajarshi Guha W Armand Guiguemde Nil Gural R Kiplin Guy Michael A E Hansen Kirsten K Hanson Andrew Hemphill Rob Hooft van Huijsduijnen Takaaki Horii Paul Horrocks Tyler B Hughes Christopher Huston Ikuo Igarashi Katrin Ingram-Sieber Maurice A Itoe Ajit Jadhav Amornrat Naranuntarat Jensen Laran T Jensen Rays H Y Jiang Annette Kaiser Jennifer Keiser Thomas Ketas Sebastien Kicka Sunyoung Kim Kiaran Kirk Vidya P Kumar Dennis E Kyle Maria Jose Lafuente Scott Landfear Nathan Lee Sukjun Lee Adele M Lehane Fengwu Li David Little Liqiong Liu Manuel Llinás Maria I Loza Aristea Lubar Leonardo Lucantoni Isabelle Lucet Louis Maes Dalu Mancama Nuha R Mansour Sandra March Sheena McGowan Iset Medina Vera Stephan Meister Luke Mercer Jordi Mestres Alvine N Mfopa Raj N Misra Seunghyun Moon John P Moore Francielly Morais Rodrigues da Costa Joachim Müller Arantza Muriana Stephen Nakazawa Hewitt Bakela Nare Carl Nathan Nathalie Narraidoo Sujeevi Nawaratna Kayode K Ojo Diana Ortiz Gordana Panic George Papadatos Silvia Parapini Kailash Patra Ngoc Pham Sarah Prats David M Plouffe Sally-Ann Poulsen Anupam Pradhan Celia Quevedo Ronald J Quinn Christopher A Rice Mohamed Abdo Rizk Andrea Ruecker Robert St Onge Rafaela Salgado Ferreira Jasmeet Samra Natalie G Robinett Ulrich Schlecht Marjorie Schmitt Filipe Silva Villela Francesco Silvestrini Robert Sinden Dennis A Smith Thierry Soldati Andreas Spitzmüller Serge Maximilian Stamm David J Sullivan William Sullivan Sundari Suresh Brian M Suzuki Yo Suzuki S Joshua Swamidass Donatella Taramelli Lauve R Y Tchokouaha Anjo Theron David Thomas Kathryn F Tonissen Simon Townson Abhai K Tripathi Valentin Trofimov Kenneth O Udenze Imran Ullah Cindy Vallieres Edgar Vigil Joseph M Vinetz Phat Voong Vinh Hoan Vu Nao-Aki Watanabe Kate Weatherby Pamela M White Andrew F Wilks Elizabeth A Winzeler Edward Wojcik Melanie Wree Wesley Wu Naoaki Yokoyama Paul H A Zollo Nada Abla Benjamin Blasco Jeremy Burrows Benoît Laleu Didier Leroy Thomas Spangenberg Timothy Wells Paul A Willis

PLoS Pathog 2016 07 28;12(7):e1005763. Epub 2016 Jul 28.

Medicines for Malaria Venture, Geneva, Switzerland.

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http://dx.doi.org/10.1371/journal.ppat.1005763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965013PMC
July 2016

Plasmodium falciparum ookinete expression of plasmepsin VII and plasmepsin X.

Malar J 2016 Feb 24;15:111. Epub 2016 Feb 24.

Division of Infectious Diseases, Department of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0760, USA.

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http://dx.doi.org/10.1186/s12936-016-1161-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765185PMC
February 2016

High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission.

Cell Host Microbe 2016 Jan 31;19(1):114-26. Epub 2015 Dec 31.

Division of Pharmacology and Drug Discovery, Department of Pediatrics, University of California San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2015.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723716PMC
January 2016

SIRP/CD47 signaling in neurological disorders.

Brain Res 2015 Oct 17;1623:74-80. Epub 2015 Mar 17.

Center of Cerebrovascular Disease Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; China-America Institute of Neuroscience, Luhe Teaching Hospital, Capital Medical University, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2015.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569528PMC
October 2015

Mutations in the P-type cation-transporter ATPase 4, PfATP4, mediate resistance to both aminopyrazole and spiroindolone antimalarials.

ACS Chem Biol 2015 Feb 5;10(2):413-20. Epub 2014 Nov 5.

Division of Pharmacology and Drug Discovery, Department of Pediatrics, ‡Division of Infectious Diseases, Department of Medicine, University of California San Diego School of Medicine , La Jolla, California 92093, United States.

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http://dx.doi.org/10.1021/cb500616xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340351PMC
February 2015

Regulation of Neuroinflammation through Programed Death-1/Programed Death Ligand Signaling in Neurological Disorders.

Front Cell Neurosci 2014 3;8:271. Epub 2014 Sep 3.

Department of Neurology, University of Pittsburgh School of Medicine , Pittsburgh, PA , USA ; Institute of Neuroscience, Luhe Hospital, Capital Medical University , Beijing , China.

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http://dx.doi.org/10.3389/fncel.2014.00271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153295PMC
September 2014

[An analysis of etiologies of fever of unknown origin in 372 patients].

Zhonghua Nei Ke Za Zhi 2014 Apr;53(4):298-302

Department of Infectious Diseases, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.

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April 2014

Algae-produced Pfs25 elicits antibodies that inhibit malaria transmission.

PLoS One 2012 16;7(5):e37179. Epub 2012 May 16.

Division of Biological Sciences, and the San Diego Center for Algae Biotechnology, University of California San Diego, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0037179PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353897PMC
September 2012

Engineered resistance to Plasmodium falciparum development in transgenic Anopheles stephensi.

PLoS Pathog 2011 Apr 21;7(4):e1002017. Epub 2011 Apr 21.

Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, California, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1002017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080844PMC
April 2011

In vitro generation of Plasmodium falciparum ookinetes.

Am J Trop Med Hyg 2010 Dec;83(6):1187-94

Division of Infectious Diseases, Department of Medicine, University of California San Diego, La Jolla, California 92093-0741, USA.

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http://dx.doi.org/10.4269/ajtmh.2010.10-0433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990030PMC
December 2010

Apical surface expression of aspartic protease Plasmepsin 4, a potential transmission-blocking target of the plasmodium ookinete.

J Biol Chem 2010 Mar 7;285(11):8076-83. Epub 2010 Jan 7.

Division of Infectious Diseases, Department of Medicine, University of California San Diego School of Medicine, La Jolla, California 92093, USA.

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http://dx.doi.org/10.1074/jbc.M109.063388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832958PMC
March 2010

An anti-Chitinase malaria transmission-blocking single-chain antibody as an effector molecule for creating a Plasmodium falciparum-refractory mosquito.

J Infect Dis 2005 Sep 27;192(5):878-87. Epub 2005 Jul 27.

Division of Infectious Diseases, Department of Medicine, University of California-San Diego School of Medicine, La Jolla, California 92093-0640, USA.

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http://dx.doi.org/10.1086/432552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265778PMC
September 2005

Plasmodium ookinete-secreted proteins secreted through a common micronemal pathway are targets of blocking malaria transmission.

J Biol Chem 2004 Jun 6;279(25):26635-44. Epub 2004 Apr 6.

Division of Infectious Diseases, Department of Medicine, University of California, San Diego, La Jolla, California 92093-0640, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M401385200
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http://dx.doi.org/10.1074/jbc.M401385200DOI Listing
June 2004

Monoclonal antibody against the Plasmodium falciparum chitinase, PfCHT1, recognizes a malaria transmission-blocking epitope in Plasmodium gallinaceum ookinetes unrelated to the chitinase PgCHT1.

Infect Immun 2002 Mar;70(3):1581-90

World Health Organization Collaborating Center for Tropical Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC127816PMC
http://dx.doi.org/10.1128/iai.70.3.1581-1590.2002DOI Listing
March 2002

Identification of novel Plasmodium gallinaceum zygote- and ookinete-expressed proteins as targets for blocking malaria transmission.

Infect Immun 2002 Jan;70(1):102-6

WHO Collaborating Center for Tropical Disease, Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC127631PMC
http://dx.doi.org/10.1128/iai.70.1.102-106.2002DOI Listing
January 2002