Fengju Chen

Fengju Chen

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Fengju Chen

Fengju Chen

Publications by authors named "Fengju Chen"

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38Publications

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SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair.

Nat Commun 2019 Sep 6;10(1):4042. Epub 2019 Sep 6.

Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, 1 Baylor Plaza, BCM 505, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1038/s41467-019-11880-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731344PMC
September 2019

Glucocorticoids Inhibit Oncogenic RUNX1-ETO in Acute Myeloid Leukemia with Chromosome Translocation t(8;21).

Theranostics 2018 8;8(8):2189-2201. Epub 2018 Mar 8.

Department of Pharmacology and Chemical Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA.

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http://dx.doi.org/10.7150/thno.22800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928880PMC
April 2019

Molecular Correlates of Metastasis by Systematic Pan-Cancer Analysis Across The Cancer Genome Atlas.

Mol Cancer Res 2019 02 6;17(2):476-487. Epub 2018 Nov 6.

Division of Biostatistics, Dan L. Duncan Comprehensive Cancer Center Baylor College of Medicine, Houston, Texas.

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http://mcr.aacrjournals.org/lookup/doi/10.1158/1541-7786.MCR
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http://dx.doi.org/10.1158/1541-7786.MCR-18-0601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359982PMC
February 2019

A Pan-Cancer Compendium of Genes Deregulated by Somatic Genomic Rearrangement across More Than 1,400 Cases.

Cell Rep 2018 07;24(2):515-527

Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.06.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092947PMC
July 2018

Prognostic Power of a Tumor Differentiation Gene Signature for Bladder Urothelial Carcinomas.

J Natl Cancer Inst 2018 05;110(5):448-459

Department of Molecular and Cellular Biology, University of Texas MD Anderson Cancer Center, Smithville, TX.

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http://dx.doi.org/10.1093/jnci/djx243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279371PMC
May 2018

Pan-Cancer Molecular Classes Transcending Tumor Lineage Across 32 Cancer Types, Multiple Data Platforms, and over 10,000 Cases.

Clin Cancer Res 2018 05 9;24(9):2182-2193. Epub 2018 Feb 9.

Dan L. Duncan Comprehensive Cancer Center Division of Biostatistics, Baylor College of Medicine, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-3378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932236PMC
May 2018

Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nat Commun 2017 08 4;8(1):199. Epub 2017 Aug 4.

Dan L. Duncan Comprehensive Cancer Center Division of Biostatistics, Baylor College of Medicine, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1038/s41467-017-00289-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543131PMC
August 2017

A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations.

Cancer Cell 2017 06 18;31(6):820-832.e3. Epub 2017 May 18.

Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502825PMC
June 2017

A Versatile Tumor Gene Deletion System Reveals a Crucial Role for FGFR1 in Breast Cancer Metastasis.

Neoplasia 2017 May 20;19(5):421-428. Epub 2017 Apr 20.

Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, United States. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2017.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402631PMC
May 2017

Overexpression of Semaphorin-3E enhances pancreatic cancer cell growth and associates with poor patient survival.

Oncotarget 2016 Dec;7(52):87431-87448

Michael E. DeBakey Department of Surgery, Division of Surgical Research, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.18632/oncotarget.13704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349999PMC
December 2016

Chronic Infection Depletes Hematopoietic Stem Cells through Stress-Induced Terminal Differentiation.

Cell Rep 2016 12;17(10):2584-2595

Section of Pediatric Infectious Diseases, Baylor College of Medicine, Houston, TX 77030, USA; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX 77030, USA; BCM Inflammation Center, Baylor College of Medicine, Houston, TX 77030, USA; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.11.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161248PMC
December 2016

Quantitative Influence of ABO Blood Groups on Factor VIII and Its Ratio to von Willebrand Factor, Novel Observations from an ARIC Study of 11,673 Subjects.

PLoS One 2015 5;10(8):e0132626. Epub 2015 Aug 5.

Puget Sound Blood Center Research Institute, Puget Sound Blood Center, Seattle, Washington, United States of America; Division of Hematology, Department of Medicine, University of Washington, School of Medicine, Seattle, Washington, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132626PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526567PMC
May 2016

Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma.

Cell Rep 2016 Mar 3;14(10):2476-89. Epub 2016 Mar 3.

Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.02.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794376PMC
March 2016

Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia.

J Hematol Oncol 2016 Mar 12;9:24. Epub 2016 Mar 12.

Department of Pharmacology, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1186/s13045-016-0252-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789278PMC
March 2016

Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma.

Authors:
W Marston Linehan Paul T Spellman Christopher J Ricketts Chad J Creighton Suzanne S Fei Caleb Davis David A Wheeler Bradley A Murray Laura Schmidt Cathy D Vocke Myron Peto Abu Amar M Al Mamun Eve Shinbrot Anurag Sethi Samira Brooks W Kimryn Rathmell Angela N Brooks Katherine A Hoadley A Gordon Robertson Denise Brooks Reanne Bowlby Sara Sadeghi Hui Shen Daniel J Weisenberger Moiz Bootwalla Stephen B Baylin Peter W Laird Andrew D Cherniack Gordon Saksena Scott Haake Jun Li Han Liang Yiling Lu Gordon B Mills Rehan Akbani Mark D M Leiserson Benjamin J Raphael Pavana Anur Donald Bottaro Laurence Albiges Nandita Barnabas Toni K Choueiri Bogdan Czerniak Andrew K Godwin A Ari Hakimi Thai H Ho James Hsieh Michael Ittmann William Y Kim Bhavani Krishnan Maria J Merino Kenna R Mills Shaw Victor E Reuter Ed Reznik Carl S Shelley Brian Shuch Sabina Signoretti Ramaprasad Srinivasan Pheroze Tamboli George Thomas Satish Tickoo Kenneth Burnett Daniel Crain Johanna Gardner Kevin Lau David Mallery Scott Morris Joseph D Paulauskis Robert J Penny Candace Shelton W Troy Shelton Mark Sherman Eric Thompson Peggy Yena Melissa T Avedon Jay Bowen Julie M Gastier-Foster Mark Gerken Kristen M Leraas Tara M Lichtenberg Nilsa C Ramirez Tracie Santos Lisa Wise Erik Zmuda John A Demchok Ina Felau Carolyn M Hutter Margi Sheth Heidi J Sofia Roy Tarnuzzer Zhining Wang Liming Yang Jean C Zenklusen Jiashan Zhang Brenda Ayala Julien Baboud Sudha Chudamani Jia Liu Laxmi Lolla Rashi Naresh Todd Pihl Qiang Sun Yunhu Wan Ye Wu Adrian Ally Miruna Balasundaram Saianand Balu Rameen Beroukhim Tom Bodenheimer Christian Buhay Yaron S N Butterfield Rebecca Carlsen Scott L Carter Hsu Chao Eric Chuah Amanda Clarke Kyle R Covington Mahmoud Dahdouli Ninad Dewal Noreen Dhalla Harsha V Doddapaneni Jennifer A Drummond Stacey B Gabriel Richard A Gibbs Ranabir Guin Walker Hale Alicia Hawes D Neil Hayes Robert A Holt Alan P Hoyle Stuart R Jefferys Steven J M Jones Corbin D Jones Divya Kalra Christie Kovar Lora Lewis Jie Li Yussanne Ma Marco A Marra Michael Mayo Shaowu Meng Matthew Meyerson Piotr A Mieczkowski Richard A Moore Donna Morton Lisle E Mose Andrew J Mungall Donna Muzny Joel S Parker Charles M Perou Jeffrey Roach Jacqueline E Schein Steven E Schumacher Yan Shi Janae V Simons Payal Sipahimalani Tara Skelly Matthew G Soloway Carrie Sougnez Angela Tam Donghui Tan Nina Thiessen Umadevi Veluvolu Min Wang Matthew D Wilkerson Tina Wong Junyuan Wu Liu Xi Jane Zhou Jason Bedford Fengju Chen Yao Fu Mark Gerstein David Haussler Katayoon Kasaian Phillip Lai Shiyun Ling Amie Radenbaugh David Van Den Berg John N Weinstein Jingchun Zhu Monique Albert Iakovina Alexopoulou Jeremiah J Andersen J Todd Auman John Bartlett Sheldon Bastacky Julie Bergsten Michael L Blute Lori Boice Roni J Bollag Jeff Boyd Erik Castle Ying-Bei Chen John C Cheville Erin Curley Benjamin Davies April DeVolk Rajiv Dhir Laura Dike John Eckman Jay Engel Jodi Harr Ronald Hrebinko Mei Huang Lori Huelsenbeck-Dill Mary Iacocca Bruce Jacobs Michael Lobis Jodi K Maranchie Scott McMeekin Jerome Myers Joel Nelson Jeremy Parfitt Anil Parwani Nicholas Petrelli Brenda Rabeno Somak Roy Andrew L Salner Joel Slaton Melissa Stanton R Houston Thompson Leigh Thorne Kelinda Tucker Paul M Weinberger Cynthia Winemiller Leigh Anne Zach Rosemary Zuna

Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare Mutations.

Cancer Res 2015 Dec 1;75(24):5341-54. Epub 2015 Dec 1.

Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, Texas. Dan L. Duncan Cancer Center, Baylor College of Medicine, One Baylor Plaza, Houston, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-1654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681596PMC
December 2015

p300 Regulates Liver Functions by Controlling p53 and C/EBP Family Proteins through Multiple Signaling Pathways.

Mol Cell Biol 2015 Sep 22;35(17):3005-16. Epub 2015 Jun 22.

Division of Pediatric General and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA

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http://dx.doi.org/10.1128/MCB.00421-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525310PMC
September 2015

Ex vivo four-dimensional lung cancer model mimics metastasis.

Ann Thorac Surg 2015 Apr 18;99(4):1149-56. Epub 2015 Feb 18.

Department of Surgery, Houston Methodist Research Institute, Houston, Texas; Department of Surgery, Weill Cornell Medical College, Houston Methodist Hospital, Houston, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.athoracsur.2014.08.085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387006PMC
April 2015

Genomics of chromophobe renal cell carcinoma: implications from a rare tumor for pan-cancer studies.

Oncoscience 2015 20;2(2):81-90. Epub 2015 Feb 20.

The Dan L. Duncan Cancer Center Division of Biostatistics, Houston, TX, USA ; Department of Medicine, Baylor College of Medicine, Houston, TX, USA ; Department of Bioinformatics and Computational Biology, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA.

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http://impactjournals.com/oncoscience/index.php?abs=130
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381700PMC
http://dx.doi.org/10.18632/oncoscience.130DOI Listing
April 2015

Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance.

Nature 2015 Jan 3;517(7533):209-13. Epub 2014 Dec 3.

1] Department of Molecular &Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA [2] Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA [3] Dan L Duncan Cancer Center and Center for Cell Gene &Therapy, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA [4] Scott Department of Urology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/nature14034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465385PMC
January 2015

Inhibition of histone H3K79 methylation selectively inhibits proliferation, self-renewal and metastatic potential of breast cancer.

Oncotarget 2014 Nov;5(21):10665-77

Department of Pharmacology, Baylor College of Medicine, Houston, TX 77030, USA. Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279401PMC
http://dx.doi.org/10.18632/oncotarget.2496DOI Listing
November 2014

[The clinical comparison of conjunctival resection with conjunctival resection and sclera fixation in the treatment of conjunctivochalasis].

Zhonghua Yan Ke Za Zhi 2014 Sep;50(9):687-90

Clinical College of Opthalmology, Tianjin Medical University, Tianjin Eye Institute, Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin 300020, China. Email:

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September 2014

Orbicularis oculi muscle transposition for repairing involutional lower eyelid entropion.

Graefes Arch Clin Exp Ophthalmol 2014 Aug 20;252(8):1315-8. Epub 2014 Jun 20.

Department of Ophthalmology, Tianjin Eye Hospital, Clinical College of Ophthalmology, Tianjin Medical University, Tianjin Key Laboratory of Ophthalmology and Vision Science, 4th Gansu Road, Heping District, Tianjin, China, 300020.

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http://dx.doi.org/10.1007/s00417-014-2694-3DOI Listing
August 2014

Thymidine phosphorylase gene variant, platelet counts and survival in gastrointestinal cancer patients treated by fluoropyrimidines.

Sci Rep 2014 Jul 16;4:5697. Epub 2014 Jul 16.

Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, P.R. China.

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http://www.nature.com/articles/srep05697
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http://dx.doi.org/10.1038/srep05697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100023PMC
July 2014

Pathway-centric integrative analysis identifies RRM2 as a prognostic marker in breast cancer associated with poor survival and tamoxifen resistance.

Neoplasia 2014 May;16(5):390-402

Department of Molecular and Cell Biology, Baylor College of Medicine, Houston, TX, USA; Verna and Marrs McLean Department of Biochemistry, Baylor College of Medicine, Houston, TX, USA; Alkek Center for Molecular Discovery, Baylor College of Medicine, Houston, TX, USA; Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2014.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198742PMC
May 2014

High-performance liquid chromatography for the determination of 3-n-butylphthalide in rat plasma by tandem quadrupole mass spectrometry: application to a pharmacokinetic study.

J Chromatogr B Analyt Technol Biomed Life Sci 2008 Jul 4;870(1):135-9. Epub 2008 Jun 4.

Department of Biopharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, No. 103, Wenhua Road, Shenyang 110016, China.

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http://dx.doi.org/10.1016/j.jchromb.2008.05.044DOI Listing
July 2008