Publications by authors named "Fen Pei"

18Publications

Nucleation seed size determines amyloid clearance and establishes a barrier to prion appearance in yeast.

Nat Struct Mol Biol 2020 06 4;27(6):540-549. Epub 2020 May 4.

Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst, MA, USA.

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June 2020

Mechanisms of Action of Autophagy Modulators Dissected by Quantitative Systems Pharmacology Analysis.

Int J Mol Sci 2020 Apr 19;21(8). Epub 2020 Apr 19.

Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.

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April 2020

QuartataWeb: Integrated Chemical-Protein-Pathway Mapping for Polypharmacology and Chemogenomics.

Bioinformatics 2020 06;36(12):3935-3937

Department of Computational and Systems Biology School of Medicine.

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June 2020

Next-Generation Antibody Therapeutics: Discovery, Development and Beyond: highlights of the third annual conference of the Chinese Antibody Society.

Antib Ther 2019 Oct 10;2(4):99-107. Epub 2019 Dec 10.

NCI Antibody Engineering Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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October 2019

Cdc48/VCP and Endocytosis Regulate TDP-43 and FUS Toxicity and Turnover.

Mol Cell Biol 2020 01 30;40(4). Epub 2020 Jan 30.

Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA

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January 2020

Quantitative Systems Pharmacological Analysis of Drugs of Abuse Reveals the Pleiotropy of Their Targets and the Effector Role of mTORC1.

Front Pharmacol 2019 8;10:191. Epub 2019 Mar 8.

Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.

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March 2019

A Quantitative Systems Pharmacology Approach to Infer Pathways Involved in Complex Disease Phenotypes.

Methods Mol Biol 2018 ;1787:207-222

Department of Computational and Systems Biology, University of Pittsburgh Drug Discovery Institute, University of Pittsburgh, Pittsburgh, PA, USA.

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February 2019

Endocytosis regulates TDP-43 toxicity and turnover.

Nat Commun 2017 12 12;8(1):2092. Epub 2017 Dec 12.

Department of Molecular and Cellular Biology, University of Arizona, Tucson, AZ, 85721, USA.

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December 2017

A dominant-negative mutant inhibits multiple prion variants through a common mechanism.

PLoS Genet 2017 Oct 30;13(10):e1007085. Epub 2017 Oct 30.

The University of Arizona, Department of Molecular and Cellular Biology, Tucson, Arizona, United States of America.

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October 2017

Role of Autophagy and Apoptosis in Non-Small-Cell Lung Cancer.

Int J Mol Sci 2017 Feb 10;18(2). Epub 2017 Feb 10.

Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong, China.

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February 2017

Distinct Prion Domain Sequences Ensure Efficient Amyloid Propagation by Promoting Chaperone Binding or Processing In Vivo.

PLoS Genet 2016 Nov 4;12(11):e1006417. Epub 2016 Nov 4.

Department of Molecular and Cellular Biology, The University of Arizona, Tucson, Arizona, United States of America.

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November 2016

Microenvironmental Effect of 2'-O-(1-Pyrenylmethyl)uridine Modified Fluorescent Oligonucleotide Probes on Sensitive and Selective Detection of Target RNA.

Anal Chem 2016 Apr 8;88(8):4448-55. Epub 2016 Apr 8.

State Key Laboratory of Natural and Biomimetic Drugs, the School of Pharmaceutical Sciences, Peking University , Beijing, 100191, China.

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April 2016

Enrichment assessment of multiple virtual screening strategies for Toll-like receptor 8 agonists based on a maximal unbiased benchmarking data set.

Chem Biol Drug Des 2015 Nov 14;86(5):1226-41. Epub 2015 Jul 14.

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Rd, Beijing, 100191, China.

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November 2015

Synthesis and biological evaluation of pyridinone analogues as novel potent HIV-1 NNRTIs.

Bioorg Med Chem 2015 Jan 14;23(1):149-59. Epub 2014 Nov 14.

Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China. Electronic address:

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January 2015

Synthesis of site-specifically phosphate-caged siRNAs and evaluation of their RNAi activity and stability.

Chemistry 2014 Sep 1;20(38):12114-22. Epub 2014 Aug 1.

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191 (China), Fax: (+86) 10-8280-5635; College of Chemistry and Chemical Engineering, University of Chinese Academy of Sciences, Beijing 100049 (China).

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September 2014