Publications by authors named "Felix Y Feng"

100Publications

Cost-Effectiveness of Metastasis-Directed Therapy in Oligorecurrent Hormone-Sensitive Prostate Cancer.

Int J Radiat Oncol Biol Phys 2020 Jun 13. Epub 2020 Jun 13.

Department of Radiation Oncology, University of California Los Angeles, Los Angeles, California; Department of Urology, University of California Los Angeles, Los Angeles, California. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2020.06.009DOI Listing
June 2020

A Signature That May Be Predictive of Early Versus Late Recurrence After Radiation Treatment for Breast Cancer That May Inform the Biology of Early, Aggressive Recurrences.

Int J Radiat Oncol Biol Phys 2020 May 17. Epub 2020 May 17.

Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan; Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2020.05.015DOI Listing
May 2020

Neddylation inactivation represses androgen receptor transcription and inhibits growth, survival and invasion of prostate cancer cells.

Neoplasia 2020 04 4;22(4):192-202. Epub 2020 Mar 4.

Division of Radiation and Cancer Biology, Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neo.2020.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058827PMC
April 2020

Transcription-Associated Cyclin-Dependent Kinases as Targets and Biomarkers for Cancer Therapy.

Cancer Discov 2020 Mar 18;10(3):351-370. Epub 2020 Feb 18.

Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2159-8290.CD-19-0528DOI Listing
March 2020

Management of Patients with Advanced Prostate Cancer: Report of the Advanced Prostate Cancer Consensus Conference 2019.

Eur Urol 2020 Apr 27;77(4):508-547. Epub 2020 Jan 27.

University of Bern, Bern, Switzerland; Department of Medical Oncology and Haematology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.eururo.2020.01.012DOI Listing
April 2020

Clinical Outcomes in Cyclin-dependent Kinase 12 Mutant Advanced Prostate Cancer.

Eur Urol 2020 Mar 20;77(3):333-341. Epub 2019 Oct 20.

Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.eururo.2019.09.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365609PMC
March 2020

Comprehensive Transcriptomic Profiling Identifies Breast Cancer Patients Who May Be Spared Adjuvant Systemic Therapy.

Clin Cancer Res 2020 01 26;26(1):171-182. Epub 2019 Sep 26.

Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-19-1038DOI Listing
January 2020

Decipher identifies men with otherwise clinically favorable-intermediate risk disease who may not be good candidates for active surveillance.

Prostate Cancer Prostatic Dis 2020 03 27;23(1):136-143. Epub 2019 Aug 27.

Department of Urology, University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41391-019-0167-9DOI Listing
March 2020

Genomic Risk Predicts Molecular Imaging-detected Metastatic Nodal Disease in Prostate Cancer.

Eur Urol Oncol 2019 11 15;2(6):685-690. Epub 2019 Jan 15.

Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA; Department of Urology, University of California San Francisco, San Francisco, CA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.euo.2018.11.002DOI Listing
November 2019

Association of imputed prostate cancer transcriptome with disease risk reveals novel mechanisms.

Nat Commun 2019 07 15;10(1):3107. Epub 2019 Jul 15.

Program in Biological and Medical Informatics, University of California San Francisco, San Francisco, CA, 94158, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-10808-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629701PMC
July 2019

Genomic Validation of 3-Tiered Clinical Subclassification of High-Risk Prostate Cancer.

Int J Radiat Oncol Biol Phys 2019 11 2;105(3):621-627. Epub 2019 Jul 2.

Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2019.06.2510DOI Listing
November 2019

Reply to J.B. Aragon-Ching.

J Clin Oncol 2019 09 1;37(25):2297-2298. Epub 2019 Jul 1.

Seth A. Rosenthal, MD, Sutter Medical Group and Sutter Cancer Centers, Sacramento, CA; Chen Hu, PhD, NRG Oncology Statistics and Data Management Center, Philadelphia, PA, and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD; Oliver Sartor, MD, Tulane University Health Services Center, New Orleans, LA; Felix Y. Feng, MD, University of California at San Francisco, San Francisco, CA; and Howard M. Sandler, MD, MS, Cedars-Sinai Medical Center, Los Angeles, CA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.19.01332DOI Listing
September 2019

Author Reply.

Urology 2019 07;129:163-164

Department of Radiation Oncology, University of California, San Francisco, CA; University of California San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, CA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.urology.2018.12.057DOI Listing
July 2019

The State of the Science on Prostate Cancer Biomarkers: The San Francisco Consensus Statement.

Eur Urol 2019 Sep 23;76(3):268-272. Epub 2019 May 23.

Department of Urology, Vanderbilt University School of Medicine, Nashville, TN, USA; Tennessee Valley Health Care System, Nashville, TN, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03022838193041
Publisher Site
http://dx.doi.org/10.1016/j.eururo.2019.05.013DOI Listing
September 2019

Novel RB1-Loss Transcriptomic Signature Is Associated with Poor Clinical Outcomes across Cancer Types.

Clin Cancer Res 2019 Jul 22;25(14):4290-4299. Epub 2019 Apr 22.

Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-19-0404DOI Listing
July 2019

Lethal clues to cancer-cell vulnerability.

Nature 2019 04;568(7753):463-464

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/d41586-019-01086-wDOI Listing
April 2019

Location of Recurrence by Gallium-68 PSMA-11 PET Scan in Prostate Cancer Patients Eligible for Salvage Radiotherapy.

Urology 2019 07 27;129:165-171. Epub 2019 Mar 27.

Department of Radiation Oncology, University of California, San Francisco, CA; University of California San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, CA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.urology.2018.12.055DOI Listing
July 2019

A Tumor-Agnostic NTRK (TRK) Inhibitor.

Cell 2019 03;177(1)

University of California, San Francisco, San Francisco, CA 94158. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2019.02.049DOI Listing
March 2019

Expanding Role of Germline DNA Repair Alterations in Prostate Cancer Risk and Early Onset.

Eur Urol 2019 09 15;76(3):338-339. Epub 2019 Mar 15.

Departments of Radiation Oncology, Urology, and Medicine and Helen Diller Family Comprehensive Cancer Center, University of California at San Francisco, San Francisco, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.eururo.2019.03.005DOI Listing
September 2019

"Lincing" the Y Chromosome to Prostate Cancer: TTTY15 Takes Center Stage.

Eur Urol 2019 09 22;76(3):327-328. Epub 2019 Feb 22.

Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.eururo.2019.02.015DOI Listing
September 2019

AUTHOR REPLY.

Urology 2019 03;125:161-162

University of California San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, CA; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA; Department of Radiology, San Francisco VA Medical Center, San Francisco, CA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.urology.2018.09.040DOI Listing
March 2019

Overview of Systemic Therapy Augmenting Management of High-risk Localized Prostate Cancer.

Eur Urol Focus 2019 03 8;5(2):168-170. Epub 2019 Feb 8.

Department of Cancer Medicine, Gustave Roussy, University of Paris Sud, Villejuif, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.euf.2019.01.015DOI Listing
March 2019

WITHDRAWN: PSMA-PET: a maturing tool.

Urology 2018 Dec 20. Epub 2018 Dec 20.

University of California San Francisco Helen Diller Family Comprehensive Cancer Center; Department of Radiology and Biomedical Imaging, University of California, San Francisco; Department of Radiology, San Francisco VA Medical Center. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.urology.2018.12.012DOI Listing
December 2018

Impact of Staging Ga-PSMA-11 PET Scans on Radiation Treatment Plansin Patients With Prostate Cancer.

Urology 2019 03 21;125:154-162. Epub 2018 Dec 21.

University of California San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, CA; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA; Department of Radiology, San Francisco VA Medical Center, San Francisco, CA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.urology.2018.09.038DOI Listing
March 2019

Reply to A. Dalla Volta et al.

J Clin Oncol 2019 02 17;37(4):351-352. Epub 2018 Dec 17.

Rahul Aggarwal, MD, University of California San Francisco, San Francisco, CA; Jiaoti Huang, MD, PhD, Duke University, Durham, NC; Joshi Alumkal, MD, Oregon Health Sciences University, Portland, OR; Felix Y. Feng, MD and Li Zhang, PhD, University of California San Francisco, San Francisco, CA; Joshua M. Stuart, PhD, University of California Santa Cruz, Santa Cruz, CA; and Eric J. Small, MD, University of California San Francisco, San Francisco, CA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.18.01487DOI Listing
February 2019

Androgen Deprivation Therapy and Overall Survival for Gleason 8 Versus Gleason 9-10 Prostate Cancer.

Eur Urol 2019 01 24;75(1):35-41. Epub 2018 Oct 24.

Harvard Medical School, Boston, MA, USA; Department of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, MA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.eururo.2018.08.033DOI Listing
January 2019

Molecular biomarkers in bladder preservation therapy for muscle-invasive bladder cancer.

Lancet Oncol 2018 12;19(12):e683-e695

Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1470-2045(18)30693-4DOI Listing
December 2018

Long non-coding RNAs in prostate cancer: Biological and clinical implications.

Mol Cell Endocrinol 2019 01 2;480:142-152. Epub 2018 Nov 2.

Dame Roma Mitchell Cancer Research Laboratories, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia; Freemasons Foundation Centre for Men's Health, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mce.2018.10.023DOI Listing
January 2019

Genomic biomarkers in prostate cancer.

Transl Androl Urol 2018 Jun;7(3):459-471

Department of Radiation Oncology, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/tau.2018.06.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043739PMC
June 2018

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.

Cell 2018 07 19;174(3):758-769.e9. Epub 2018 Jul 19.

Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco (UCSF), San Francisco, CA, USA; Division of Hematology and Oncology, Department of Medicine, UCSF, San Francisco, CA, USA; Department of Radiation Oncology, UCSF, San Francisco, CA, USA; Department of Urology, UCSF, San Francisco, CA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2018.06.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425931PMC
July 2018

Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19.

Cell 2018 07 19;174(3):564-575.e18. Epub 2018 Jul 19.

Princess Margaret Cancer Center, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 2M9, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2018.06.014DOI Listing
July 2018

Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study.

J Clin Oncol 2018 08 9;36(24):2492-2503. Epub 2018 Jul 9.

Rahul Aggarwal, Li Zhang, Felix Y. Feng, Paul Lloyd, Jack Youngren, Adam Foye, Denise Playdle, Charles J. Ryan, and Eric J. Small, University of California San Francisco, San Francisco; Alana S. Weinstein, Verena Friedl, Can Zhang, Christopher K. Wong, Vlado Uzunangelov, Artem Sokolov, Yulia Newton, and Joshua M. Stuart, University of California Santa Cruz, Santa Cruz; Owen N. Witte and Matthew Rettig, University of California Los Angeles, Los Angeles; Christopher P. Evans and Primo Lara, University of California Davis, Davis, CA; Jiaoti Huang, Duke University, Durham, NC; Joshi J. Alumkal, George V. Thomas, and Tomasz M. Beer, Oregon Health Sciences University, Portland, OR; Martin Gleave and Kim N. Chi, University of British Columbia, Vancouver, British Columbia, Canada; Lawrence True, University of Washington, Seattle, WA; Himisha Beltran and Mark A. Rubin, Weill Cornell Medicine, New York, NY; and Francesca Demichelis, University of Trento, Trento, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2017.77.6880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366813PMC
August 2018

Prostate cancer in the era of "Omic" medicine: recognizing the importance of DNA damage repair pathways.

Ann Transl Med 2018 May;6(9):161

Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/atm.2018.05.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985268PMC
May 2018

Inactivation of CDK12 Delineates a Distinct Immunogenic Class of Advanced Prostate Cancer.

Cell 2018 06;173(7):1770-1782.e14

Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA; Department of Urology, University of Michigan, Ann Arbor, MI 48109, USA; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2018.04.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084431PMC
June 2018

EWS/ETS-Driven Ewing Sarcoma Requires BET Bromodomain Proteins.

Cancer Res 2018 08 13;78(16):4760-4773. Epub 2018 Jun 13.

Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, BRBII/III, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-18-0484DOI Listing
August 2018

Comprehensive Molecular Profiling Identifies FOXM1 as a Key Transcription Factor for Meningioma Proliferation.

Cell Rep 2018 03;22(13):3672-3683

Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA, USA; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2018.03.013DOI Listing
March 2018

Concurrent Veliparib With Chest Wall and Nodal Radiotherapy in Patients With Inflammatory or Locoregionally Recurrent Breast Cancer: The TBCRC 024 Phase I Multicenter Study.

J Clin Oncol 2018 05 20;36(13):1317-1322. Epub 2018 Mar 20.

Reshma Jagsi, Felix Y. Feng, Corey Speers, Michael Sabel, Anne F. Schott, and Lori Pierce, University of Michigan; Kent A. Griffith, University of Michigan School of Public Health, Ann Arbor, MI; Jennifer R. Bellon and Beth Overmoyer, Dana-Farber Cancer Institute, Boston, MA; Wendy A. Woodward, The University of Texas MD Anderson Cancer Center, Houston, TX; Janet K. Horton, Duke University School of Medicine, Durham, NC; and Alice Ho, Cedars-Sinai Medical Center, Los Angeles, CA.

View Article

Download full-text PDF

Source
http://ascopubs.org/doi/10.1200/JCO.2017.77.2665
Publisher Site
http://dx.doi.org/10.1200/JCO.2017.77.2665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804907PMC
May 2018

Clinical and Genomic Characterization of Low-Prostate-specific Antigen, High-grade Prostate Cancer.

Eur Urol 2018 08 22;74(2):146-154. Epub 2018 Feb 22.

Harvard Medical School, Boston, MA, USA; Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, MA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.eururo.2018.01.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615042PMC
August 2018

Targeting Androgen Receptor and DNA Repair in Metastatic Castration-Resistant Prostate Cancer: Results From NCI 9012.

J Clin Oncol 2018 04 20;36(10):991-999. Epub 2017 Dec 20.

Maha Hussain, Robert H. Lurie Comprehensive Cancer Center, Northwestern University; Walter M. Stadler, University of Chicago, Chicago; Daniel H. Shevrin, NorthShore University Health System, Evanston, IL; Maha Hussain, Stephanie Daignault-Newton, Lakshmi P. Kunju, Javed Siddiqui, Yi-Mi Wu, Dan Robinson, Robert J. Lonigro, Xuhong Cao, Scott A. Tomlins, Rohit Mehra, David C. Smith, Megan V. Caram, and Arul M. Chinnaiyan, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; Przemyslaw W. Twardowski, City of Hope Cancer Center, Duarte; Felix Y. Feng, University of California San Francisco, San Francisco, CA; Costantine Albany, Simon Cancer Center, Indiana University, Indianapolis, IN; Mark N. Stein, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ; Kathleen A. Cooney, University of Utah, Salt Lake City, UT; Bruce Montgomery, University of Washington, Seattle, WA; Emmanuel S. Antonarakis, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD; Paul G. Corn, University of Texas MD Anderson Cancer Center, Houston, TX; Young E. Whang, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC; and Karen E. Knudsen, Thomas Jefferson University, Philadelphia, PA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2017.75.7310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075827PMC
April 2018

Oncogenic Role of THOR, a Conserved Cancer/Testis Long Non-coding RNA.

Cell 2017 Dec;171(7):1559-1572.e20

Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, USA; Department of Cellular and Molecular Biology, University of Michigan, Ann Arbor, MI, USA; Department of Pathology, University of Michigan, Ann Arbor, MI, USA; Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI, USA; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI, USA; Department of Urology, University of Michigan, Ann Arbor, MI, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2017.11.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734106PMC
December 2017