Publications by authors named "Felipe F Casanueva"

100Publications

Ketogenic diets as treatment of obesity and type 2 diabetes mellitus.

Rev Endocr Metab Disord 2020 Sep;21(3):381-397

Division of Endocrinology, Department of Medicine, Santiago de Compostela University (USC), Complejo Hospitalario Universitario de Santiago, Instituto de Investigación Sanitaria de Santiago (IDIS), Santiago, Spain.

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http://dx.doi.org/10.1007/s11154-020-09580-7DOI Listing
September 2020

Analysis of platelets from a diet-induced obesity rat model: elucidating platelet dysfunction in obesity.

Sci Rep 2020 08 4;10(1):13104. Epub 2020 Aug 4.

Platelet Proteomics Group, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade Santiago de Compostela, Avda de Barcelona s/n, 15782, Santiago de Compostela, Spain.

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http://dx.doi.org/10.1038/s41598-020-70162-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403150PMC
August 2020

Pituitary Tumors Centers of Excellence.

Endocrinol Metab Clin North Am 2020 09 15;49(3):553-564. Epub 2020 Jul 15.

Division of Endocrinology, Complejo Hospitalario Universitario de Santiago (USC/SERGAS), Instituto de Investigacion Sanitaria de Santiago (IDIS), Rúa da Choupana, S/N, Santiago de Compostela, A Coruña 15706, Spain; CIBER Fisiopatología de la Obesidad y la Nutrición (CIBERobn), Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.ecl.2020.05.010DOI Listing
September 2020

Association between variation of circulating 25-OH vitamin D and methylation of secreted frizzled-related protein 2 in colorectal cancer.

Clin Epigenetics 2020 Jun 9;12(1):83. Epub 2020 Jun 9.

Deparment of Endocrinology and Nutrition, Virgen de la Victoria University Hospital, Institute of Biomedical Research in Malaga (IBIMA) and University of Malaga, Malaga, Spain.

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http://dx.doi.org/10.1186/s13148-020-00875-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285750PMC
June 2020

Methylation Levels in Leukocytes From Women With Breast Cancer Is Modulated by Adiposity, Menopausal State, and the Mediterranean Diet.

Front Endocrinol (Lausanne) 2020 23;11:245. Epub 2020 Apr 23.

Laboratory of Epigenomics in Endocrinology and Nutrition (EpiEndoNut), Instituto de Investigacion Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago de Compostela (CHUS/SERGAS), Santiago de Compostela, Spain.

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http://dx.doi.org/10.3389/fendo.2020.00245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191069PMC
April 2020

Vesicles Shed by Pathological Murine Adipocytes Spread Pathology: Characterization and Functional Role of Insulin Resistant/Hypertrophied Adiposomes.

Int J Mol Sci 2020 03 24;21(6). Epub 2020 Mar 24.

Grupo Obesidómica, Área de Endocrinología, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Xerencia de Xestión Integrada de Santiago (XXIS/SERGAS), 15706 Santiago de Compostela, Spain.

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http://dx.doi.org/10.3390/ijms21062252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139903PMC
March 2020

Confusion in the nomenclature of ketogenic diets blurs evidence.

Rev Endocr Metab Disord 2020 03;21(1):1-3

Division of Endocrinology, Santiago de Compostela University and CIBEROBN, Santiago de Compostela, Spain.

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http://dx.doi.org/10.1007/s11154-020-09546-9DOI Listing
March 2020

An energy restriction-based weight loss intervention is able to reverse the effects of obesity on the expression of liver tumor-promoting genes.

FASEB J 2020 02 16;34(2):2312-2325. Epub 2019 Dec 16.

Laboratory of Epigenomics in Endocrinology and Nutrition, Instituto de Investigacion Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago de Compostela (CHUS/SERGAS), Santiago de Compostela, Spain.

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http://dx.doi.org/10.1096/fj.201901147RRDOI Listing
February 2020

Leptin, Obesity, and Leptin Resistance: Where Are We 25 Years Later?

Nutrients 2019 Nov 8;11(11). Epub 2019 Nov 8.

CIBER de Fisiopatologia de la Obesidad y Nutricion (CIBERobn), Instituto Salud Carlos III, 28029 Madrid, Spain.

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http://dx.doi.org/10.3390/nu11112704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893721PMC
November 2019

Effect of a Very-Low-Calorie Ketogenic Diet on Circulating Myokine Levels Compared with the Effect of Bariatric Surgery or a Low-Calorie Diet in Patients with Obesity.

Nutrients 2019 Oct 4;11(10). Epub 2019 Oct 4.

Division of Endocrinology, Department of Medicine, Complejo Hospitalario Universitario de Santiago (CHUS/SERGAS), Instituto de Investigacion Sanitaria de Santiago (IDIS), 15706 Santiago de Compostela, Spain.

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http://dx.doi.org/10.3390/nu11102368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835835PMC
October 2019

Novel DNA Methylation Profile Following Neoadjuvant Therapy in Colorectal Cancer Patients with Different Grades of BMI.

J Clin Med 2019 Jul 17;8(7). Epub 2019 Jul 17.

Department of Endocrinology and Nutrition, Virgen de la Victoria University Hospital, University of Malaga (IBIMA), 29010 Málaga, Spain.

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http://dx.doi.org/10.3390/jcm8071041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678889PMC
July 2019

ANGPTL-4 is Associated with Obesity and Lipid Profile in Children and Adolescents.

Nutrients 2019 Jun 14;11(6). Epub 2019 Jun 14.

Endocrine Physiopathology Group, Instituto Investigación Sanitaria Santiago de Compostela (IDIS), Complejo Hospitalario Universitario Santiago de Compostela (CHUS/SERGAS), 15706 Santiago de Compostela, Spain.

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http://dx.doi.org/10.3390/nu11061340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628529PMC
June 2019

Associations between neuropsychological performance and appetite-regulating hormones in anorexia nervosa and healthy controls: Ghrelin's putative role as a mediator of decision-making.

Mol Cell Endocrinol 2019 11 20;497:110441. Epub 2019 May 20.

Department of Psychiatry, University Hospital of Bellvitge-IDIBELL, Barcelona, Spain; CIBER Fisiopatología Obesidad y Nutrición (CIBERobn), Instituto de Salud Carlos III, Barcelona, Spain; Department of Clinical Sciences, School of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2019.04.021DOI Listing
November 2019

A step forward in our common endeavor.

Rev Endocr Metab Disord 2019 03;20(1)

Santiago de Compostela University, Santiago de Compostela, Spain.

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http://dx.doi.org/10.1007/s11154-019-09500-4DOI Listing
March 2019

GLP-1 induces alpha cell proliferation and overrides leptin suppression induced by negative energy balance in vagotomized rats.

J Cell Biochem 2019 09 17;120(9):14573-14584. Epub 2019 Apr 17.

Endocrine, Cardiovascular & Metabolic Research, Unit for Multidisciplinary Research in Biomedicine (UMIB), University of Porto, Porto, Portugal.

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http://dx.doi.org/10.1002/jcb.28719DOI Listing
September 2019

Uroguanylin Improves Leptin Responsiveness in Diet-Induced Obese Mice.

Nutrients 2019 Mar 30;11(4). Epub 2019 Mar 30.

Department of Physiology, CIMUS, Universidade de Santiago de Compostela - Instituto de Investigación Sanitaria, 15782 Santiago de Compostela, Spain.

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https://www.mdpi.com/2072-6643/11/4/752
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http://dx.doi.org/10.3390/nu11040752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520813PMC
March 2019

Oxidative Stress Induced by Excess of Adiposity Is Related to a Downregulation of Hepatic SIRT6 Expression in Obese Individuals.

Oxid Med Cell Longev 2018 23;2018:6256052. Epub 2018 Dec 23.

CIBER de Fisiopatologia de la Obesidad y Nutricion (CIBERobn), Instituto Salud Carlos III, Madrid, Spain.

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http://dx.doi.org/10.1155/2018/6256052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317113PMC
January 2019

GPVI surface expression and signalling pathway activation are increased in platelets from obese patients: Elucidating potential anti-atherothrombotic targets in obesity.

Atherosclerosis 2019 02 25;281:62-70. Epub 2018 Dec 25.

Platelet Proteomics Group, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade Santiago de Compostela, Santiago de Compostela, Spain; Instituto de Investigación Sanitaria de Santiago (IDIS), Santiago de Compostela, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00219150183155
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http://dx.doi.org/10.1016/j.atherosclerosis.2018.12.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403451PMC
February 2019

A Combination of Proteomic Approaches Identifies A Panel of Circulating Extracellular Vesicle Proteins Related to the Risk of Suffering Cardiovascular Disease in Obese Patients.

Proteomics 2019 01 27;19(1-2):e1800248. Epub 2018 Dec 27.

Platelet Proteomics Group, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade Santiago de Compostela, Instituto de Investigación Sanitaria de Santiago (IDIS), Santiago de Compostela, Spain.

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http://dx.doi.org/10.1002/pmic.201800248DOI Listing
January 2019

Anti-obesity activity of OBEX is regulated by activation of thermogenesis and decreasing adiposity gain.

Sci Rep 2018 11 21;8(1):17155. Epub 2018 Nov 21.

Lab de Endocrinología Molecular, Instituto de Investigaciones Sanitarias de Santiago de Compostela (IDIS), Complejo Hospitalario de Santiago (CHUS), A Coruña, Spain.

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http://dx.doi.org/10.1038/s41598-018-34840-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249269PMC
November 2018

Circulating Pro-Uroguanylin Levels In Children And Their Relation To Obesity, Sex And Puberty.

Sci Rep 2018 09 28;8(1):14541. Epub 2018 Sep 28.

Fisiopatología Endocrina, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago de Compostela (CHUS/SERGAS), Santiago de Compostela, Spain.

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http://dx.doi.org/10.1038/s41598-018-32767-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162323PMC
September 2018

Effect of A Very Low-Calorie Ketogenic Diet on Food and Alcohol Cravings, Physical and Sexual Activity, Sleep Disturbances, and Quality of Life in Obese Patients.

Nutrients 2018 Sep 21;10(10). Epub 2018 Sep 21.

Division of Endocrinology, Department of Medicine, Molecular and Cellular Endocrinology Area, Complejo Hospitalario Universitario de Santiago (CHUS), Instituto de Investigación Sanitaria de Santiago (IDIS), and Santiago de Compostela University (USC), Santiago de Compostela 15706, Spain.

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http://dx.doi.org/10.3390/nu10101348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213862PMC
September 2018

A Consensus Statement on acromegaly therapeutic outcomes.

Nat Rev Endocrinol 2018 09;14(9):552-561

Department of Endocrinology and Metabolism, San Raffaele University Hospital Milan, Milan, Italy.

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http://dx.doi.org/10.1038/s41574-018-0058-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136157PMC
September 2018

Symptomatic androgen deficiency develops only when both total and free testosterone decline in obese men who may have incident biochemical secondary hypogonadism: Prospective results from the EMAS.

Clin Endocrinol (Oxf) 2018 10 23;89(4):459-469. Epub 2018 Jul 23.

Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, University of Manchester and NIHR Manchester Musculoskeletal Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester, UK.

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http://dx.doi.org/10.1111/cen.13756DOI Listing
October 2018

Inflammatory myopathy in the context of an unusual overlapping laminopathy.

Arch Endocrinol Metab 2018 Jun 17;62(3):376-382. Epub 2018 May 17.

UETeM - Molecular Pathology Group. IDIS-CIMUS, University of Santiago de Compostela, Spain.

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http://dx.doi.org/10.20945/2359-3997000000048DOI Listing
June 2018

An Epigenetic Signature in Adipose Tissue Is Linked to Nicotinamide N-Methyltransferase Gene Expression.

Mol Nutr Food Res 2018 Apr 24:e1700933. Epub 2018 Apr 24.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona, Girona, 77190 Spain, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Madrid, 28029, Spain.

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http://dx.doi.org/10.1002/mnfr.201700933DOI Listing
April 2018

Resting metabolic rate of obese patients under very low calorie ketogenic diet.

Nutr Metab (Lond) 2018 17;15:18. Epub 2018 Feb 17.

1Division of Endocrinology, Department of Medicine, Molecular and Cellular Endocrinology Area, Complejo Hospitalario Universitario de Santiago (CHUS), Instituto de Investigación Sanitaria de Santiago (IDIS), Travesia da Choupana street s/n, 15706 Santiago de Compostela, La Coruña Spain.

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http://dx.doi.org/10.1186/s12986-018-0249-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816424PMC
February 2018

Reproductive Hormone Levels Predict Changes in Frailty Status in Community-Dwelling Older Men: European Male Ageing Study Prospective Data.

J Clin Endocrinol Metab 2018 02;103(2):701-709

Andrology Research Unit, Division of Diabetes, Endocrinology, and Gastroenterology, School of Medical Sciences, Faculty of Biology, Medicine, and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom.

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http://dx.doi.org/10.1210/jc.2017-01172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800832PMC
February 2018

Elevated luteinizing hormone despite normal testosterone levels in older men-natural history, risk factors and clinical features.

Clin Endocrinol (Oxf) 2018 03 25;88(3):479-490. Epub 2017 Dec 25.

Manchester Academic Health Sciences Centre, Faculty of Medical and Human Sciences, Institute of Human Development, Centre for Endocrinology and Diabetes, Andrology Research Unit, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1111/cen.13524DOI Listing
March 2018

Bone mineral density in familial partial lipodystrophy.

Clin Endocrinol (Oxf) 2018 Jan 20;88(1):44-50. Epub 2017 Nov 20.

UETeM-Molecular Pathology Group, Department of Medicine, IDIS-CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.

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http://dx.doi.org/10.1111/cen.13504DOI Listing
January 2018

Evolution and bad prognostic value of advanced glycation end products after acute heart failure: relation with body composition.

Cardiovasc Diabetol 2017 09 15;16(1):115. Epub 2017 Sep 15.

Laboratorio no. 6. Edif. Consultas externas (planta -2), Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complexo Hospitalario Universitario de Santiago de Compostela (CHUS), SERGAS, Travesía da Choupana s/n, Santiago de Compostela, 15706, A Coruña, Spain.

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http://dx.doi.org/10.1186/s12933-017-0598-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602867PMC
September 2017

Acid-base safety during the course of a very low-calorie-ketogenic diet.

Endocrine 2017 Oct 15;58(1):81-90. Epub 2017 Sep 15.

Division of Endocrinology, Department of Medicine, Complejo Hospitalario Universitario de Santiago (CHUS), Santiago de Compostela, Spain.

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http://dx.doi.org/10.1007/s12020-017-1405-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608861PMC
October 2017

Nonandrogenic Anabolic Hormones Predict Risk of Frailty: European Male Ageing Study Prospective Data.

J Clin Endocrinol Metab 2017 08;102(8):2798-2806

Andrology Research Unit, Division of Diabetes, Endocrinology and Gastroenterology, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom.

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http://dx.doi.org/10.1210/jc.2017-00090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546856PMC
August 2017

Obesity and menopause modify the epigenomic profile of breast cancer.

Endocr Relat Cancer 2017 07 25;24(7):351-363. Epub 2017 Apr 25.

Cancer Epigenetics and Biology Program (PEBC)Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain

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http://dx.doi.org/10.1530/ERC-16-0565DOI Listing
July 2017

Type 1 familial partial lipodystrophy: understanding the Köbberling syndrome.

Endocrine 2016 Nov 30;54(2):411-421. Epub 2016 Jul 30.

UETeM-Molecular Pathology Group, Department of Medicine, IDIS-CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.

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http://dx.doi.org/10.1007/s12020-016-1002-xDOI Listing
November 2016

Effect of DHA supplementation in a very low-calorie ketogenic diet in the treatment of obesity: a randomized clinical trial.

Endocrine 2016 Oct 27;54(1):111-122. Epub 2016 Apr 27.

Medical Department Pronokal Group, PronokalGroup, Barcelona, Spain.

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http://dx.doi.org/10.1007/s12020-016-0964-zDOI Listing
October 2016

Visceral and subcutaneous adipose tissue express and secrete functional alpha2hsglycoprotein (fetuin a) especially in obesity.

Endocrine 2017 Feb 14;55(2):435-446. Epub 2016 Oct 14.

Grupo Obesidómica, Área de Endocrinología, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Xerencia de Xestión Integrada de Santiago (XXIS/SERGAS), Santiago de Compostela, Spain.

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http://dx.doi.org/10.1007/s12020-016-1132-1DOI Listing
February 2017

Changes in prevalence of obesity and high waist circumference over four years across European regions: the European male ageing study (EMAS).

Endocrine 2017 Feb 13;55(2):456-469. Epub 2016 Oct 13.

Department of Medicine, CIBER de Fisiopatologia Obesidad y Nutricion (CB06/03), Instituto Salud Carlos III, Complejo Hospitalario Universitario de Santiago (CHUS), Santiago de Compostela University, Santiago de Compostela, Spain.

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http://dx.doi.org/10.1007/s12020-016-1135-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5272876PMC
February 2017

Impact of Mean Cell Hemoglobin on Hb A1c-Defined Glycemia Status.

Clin Chem 2016 Dec 27;62(12):1570-1578. Epub 2016 Sep 27.

Department of Biochemistry and Molecular Biology.

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http://dx.doi.org/10.1373/clinchem.2016.257659DOI Listing
December 2016

Obesity treatment by very low-calorie-ketogenic diet at two years: reduction in visceral fat and on the burden of disease.

Endocrine 2016 Dec 13;54(3):681-690. Epub 2016 Sep 13.

CIBER Fisiopatología de la Obesidad y la Nutrición (CIBERobn), Santiago de Compostela, Spain.

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http://link.springer.com/10.1007/s12020-016-1050-2
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http://dx.doi.org/10.1007/s12020-016-1050-2DOI Listing
December 2016

Prevention, diagnosis, and treatment of obesity. 2016 position statement of the Spanish Society for the Study of Obesity.

Endocrinol Diabetes Nutr 2017 Mar 16;64 Suppl 1:15-22. Epub 2016 Aug 16.

Departamento de Medicina, Universidad de Santiago, Compejo Hospitalario Universitario de Santiago (CHUS), CIBERobn (CIBER de Fisiopatología de la Obesidad y Nutrición, ISCIII), Santiago de Compostela, España.

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http://dx.doi.org/10.1016/j.endonu.2016.07.002DOI Listing
March 2017

Foreword.

Prog Mol Biol Transl Sci 2016 ;138:xiii-xiv

Professor of Medicine.

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http://dx.doi.org/10.1016/S1877-1173(16)00025-9DOI Listing
January 2017

Regulation of Growth Hormone by the Splanchnic Area.

Prog Mol Biol Transl Sci 2016 6;138:41-60. Epub 2016 Jan 6.

Grupo Fisiopatología Endocrina, Instituto de Investigacion Sanitaria de Santiago de Compostela (IDIS), Complexo Hospitalario Universitario de Santiago (CHUS/SERGAS), Spain; Pediatric Department, Universidade de Santiago de Compostela, Instituto de Investigacion Sanitaria de Santiago de Compostela (IDIS), Complexo Hospitalario Universitario de Santiago (CHUS/SERGAS), Spain. Electronic address:

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http://dx.doi.org/10.1016/bs.pmbts.2015.10.007DOI Listing
January 2017

Distinct phosphorylation sites on the ghrelin receptor, GHSR1a, establish a code that determines the functions of ß-arrestins.

Sci Rep 2016 Mar 3;6:22495. Epub 2016 Mar 3.

Área de Endocrinología Molecular y Celular, Instituto de Investigación Sanitaria de Santiago (IDIS), Complejo Hospitalario Universitario de Santiago (CHUS), Servicio Gallego de Salud (SERGAS), Santiago de Compostela, Spain.

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http://dx.doi.org/10.1038/srep22495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776146PMC
March 2016

Low Free Testosterone Is Associated with Hypogonadal Signs and Symptoms in Men with Normal Total Testosterone.

J Clin Endocrinol Metab 2016 07 24;101(7):2647-57. Epub 2016 Feb 24.

Department of Clinical and Experimental Medicine (L.A., B.D., D.V.), KU Leuven, Laboratory of Clinical and Experimental Endocrinology, Leuven, Belgium; Department of Cellular and Molecular Medicine (L.A., M.R.L., F.C.), KU Leuven, Laboratory of Molecular Endocrinology, Leuven, Belgium; Department of Endocrinology (L.A., B.D., D.V.), University Hospitals Leuven, Leuven, Belgium; Andrology Research Unit (F.C.W.W., T.B.A.), Endocrinology and Diabetes Research Group, Institute of Human Development, Faculty of Medical and Human Sciences, The University of Manchester, Manchester, UK; Manchester Royal Infirmary (F.C.W.W.), Central Manchester University Hospitals National Health Services (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Arthritis Research UK Centre of Epidemiology (T.W.O.N., S.R.P.), The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK; National Institute for Health Research Manchester Musculoskeletal Biomedical Research Unit (T.W.O.N.), Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Clinical and Experimental Medicine (M.R.L.), KU Leuven, Laboratory of Gerontology and Geriatrics, Leuven, Belgium; Department of Surgery and Cancer, Imperial College London (I.T.H.), Hammersmith Campus, London, UK; Department of Physiology (I.T.H.), Institute of Biomedicine, University of Turku, Turku, Finland; Department of Human Nutrition (M.E.J.L.), University of Glasgow, Glasgow, UK; Department of Clinical Biochemistry (B.G.K.), University Hospital of South Manchester, Manchester, UK; Sexual Medicine and Andrology Unit (G.R.), Department of Experimental Clinical and Biochemical Sciences, University of Florence, Florence, Italy; Endocrinology Unit (G.F.), Department of Experimental Clinical and Biochemical Sciences, University of Florence, Florence, Italy; Department of Obstetrics, Gynaecology and Andrology (G.B.), Albert Szent-György Medica

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http://dx.doi.org/10.1210/jc.2015-4106DOI Listing
July 2016

"Food Addiction" in Patients with Eating Disorders is Associated with Negative Urgency and Difficulties to Focus on Long-Term Goals.

Front Psychol 2016 2;7:61. Epub 2016 Feb 2.

Department of Psychiatry, University Hospital of Bellvitge-IDIBELLBarcelona, Spain; Ciber Fisiopatologia Obesidad y Nutrición, Instituto Salud Carlos IIIBarcelona, Spain; Department of Clinical Sciences, School of Medicine, University of BarcelonaBarcelona, Spain.

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http://dx.doi.org/10.3389/fpsyg.2016.00061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735728PMC
February 2016

Orexin and sleep quality in anorexia nervosa: Clinical relevance and influence on treatment outcome.

Psychoneuroendocrinology 2016 Mar 21;65:102-8. Epub 2015 Dec 21.

Department of Psychiatry, University Hospital of Bellvitge-IDIBELL, Barcelona, Spain; CIBER Fisiopatología Obesidad y Nutrición (CIBERobn), Instituto Salud Carlos III, Madrid, Spain; Department of Clinical Sciences, School of Medicine, University of Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.psyneuen.2015.12.014DOI Listing
March 2016

The role of the obestatin/GPR39 system in human gastric adenocarcinomas.

Oncotarget 2016 Feb;7(5):5957-71

Área de Endocrinología Molecular y Celular, Instituto de Investigación Sanitaria de Santiago (IDIS), Complejo Hospitalario Universitario de Santiago (CHUS), Servicio Gallego de Salud (SERGAS), Santiago de Compostela, Spain.

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http://dx.doi.org/10.18632/oncotarget.6718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868733PMC
February 2016

Chronic widespread pain is associated with worsening frailty in European men.

Age Ageing 2016 Mar 17;45(2):268-74. Epub 2015 Dec 17.

Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust-Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1093/ageing/afv170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776622PMC
March 2016

Uroguanylin Action in the Brain Reduces Weight Gain in Obese Mice via Different Efferent Autonomic Pathways.

Diabetes 2016 Feb 13;65(2):421-32. Epub 2015 Nov 13.

Department of Physiology, Center for Research in Molecular Medicine and Chronic Diseases, Universidade de Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain CIBER Fisiopatología de la Obesidad y Nutrición, Spain

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http://diabetes.diabetesjournals.org/lookup/doi/10.2337/db15
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http://dx.doi.org/10.2337/db15-0889DOI Listing
February 2016

Olfaction in eating disorders and abnormal eating behavior: a systematic review.

Front Psychol 2015 30;6:1431. Epub 2015 Sep 30.

Department of Psychiatry, University Hospital of Bellvitge-IDIBELL Barcelona, Spain ; CIBER de Fisiopatologia de la Obesidad y Nutrición -ISCIII Barcelona, Spain ; Department of Clinical Sciences, School of Medicine, University of Barcelona Barcelona, Spain.

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http://dx.doi.org/10.3389/fpsyg.2015.01431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588114PMC
October 2015

Comparative secretome analysis of rat stomach under different nutritional status.

Data Brief 2015 Jun 13;3:62-6. Epub 2015 Feb 13.

Grupo Fisiopatologia Endocrina, Instituto de Investigacion Sanitaria de Santiago de Compostela (IDIS), Complexo Hospitalario Universitario de Santiago (CHUS/SERGAS), Santiago de Compostela, Spain ; CIBER Fisiopatologia Obesidad y Nutricion (CB06/03), Instituto de Salud Carlos III, Santiago de Compostela, Spain.

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http://dx.doi.org/10.1016/j.dib.2015.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510049PMC
June 2015

β-Arrestin scaffolds and signaling elements essential for the obestatin/GPR39 system that determine the myogenic program in human myoblast cells.

Cell Mol Life Sci 2016 Feb 27;73(3):617-35. Epub 2015 Jul 27.

Área de Endocrinología Molecular y Celular, Instituto de Investigación Sanitaria de Santiago (IDIS), Complejo Hospitalario Universitario de Santiago (CHUS), Servicio Gallego de Salud (SERGAS), Santiago de Compostela, Spain.

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http://link.springer.com/10.1007/s00018-015-1994-z
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http://dx.doi.org/10.1007/s00018-015-1994-zDOI Listing
February 2016

CILAIR-Based Secretome Analysis of Obese Visceral and Subcutaneous Adipose Tissues Reveals Distinctive ECM Remodeling and Inflammation Mediators.

Sci Rep 2015 Jul 22;5:12214. Epub 2015 Jul 22.

1] Grupo Obesidómica, Instituto de Investigación Sanitaria de Santiago (IDIS), Xerencia de Xestión Integrada de Santiago (SERGAS), Santiago de Compostela, Spain [2] CIBER Fisiopatología Obesidad y Nutrición (CB06/03), Instituto de Salud Carlos III, Spain.

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http://dx.doi.org/10.1038/srep12214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648467PMC
July 2015

Circulating Betatrophin Levels Are Increased in Anorexia and Decreased in Morbidly Obese Women.

J Clin Endocrinol Metab 2015 Sep 14;100(9):E1188-96. Epub 2015 Jul 14.

Grupo Fisiopatología Endocrina (S.B.-F., C.F., L.M.S., C.C.), Instituto de Investigación Sanitaria de Santiago de Compostela, Complejo Hospitalario, Departamento de Pediatría (S.B.-F.), Universitario de Santiago de Compostela, 15705 Santiago de Compostela, Spain; Centro de Investigación Biomédica en Red Fisiopatología Obesidad y Nutrición (S.B.-F., L.M.S., F.F.C., C.D., Z.A., R.B., C.B., R.d.l.T., J.C.F.-G., J.M.F.-R., G.F., J.G.-A., S.J.-M., F.J.T., F.F.-A., R.N.), Instituto Salud Carlos III, 28029 Madrid, Spain; Department of Physiology (C.F., C.D., R.N.), Center for Research in Molecular Medicine and Chronic Diseases, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, 15782, Spain; Department of Psychiatry (Z.A., S.J.-M., F.F.-A.), University Hospital of Bellvitge-Institut d"Investigació Biomèdica de Bellvitge, 08907 Barcelona, Spain; Department of Psychological, Personality, Evaluation, and Treatment (R.B.), University of Valencia, 46022 Valencia, Spain; Department of Basic Psychology, Clinic, and Psychobiology (C.B.), University Jaume I, 12071 Castelló, Spain; Human Pharmacology and Clinical Neurosciences Research Group (R.d.l.T.), Neuroscience Research Program, Hospital del Mar Medical Research Institute, Center for Genomic Regulation (X.E.), and Centro de Investigación Biomédica en Red en Epidemiología y Salud Pública (X.E.), 08003 Barcelona, Spain; Department of Experimental and Health Sciences (R.d.l.T.), Universitat Pompeu Fabra Barcelona, 08950 Barcelona, Spain; Department of Diabetes, Endocrinology, and Nutrition (J.C.F.-G., F.J.T.), Hospital Clínico Universitario Virgen de Victoria (IBIMA), 29010 Málaga, Spain; Department of Diabetes, Endocrinology, and Nutrition (J.M.F.-R.), Institut d'Investigació Biomèdica de Girona, Hospital Dr Josep Trueta, 17007 Girona, Spain; Department of Endocrinology and Nutrition (G.F., J.G.-A.), Clínica Universidad de Navarra, University of Navarra, Institut

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http://dx.doi.org/10.1210/JC.2015-1595DOI Listing
September 2015

Modulation of Higher-Order Olfaction Components on Executive Functions in Humans.

PLoS One 2015 17;10(6):e0130319. Epub 2015 Jun 17.

Department of Psychiatry, University Hospital of Bellvitge-IDIBELL, Barcelona, Spain; CIBER Fisiopatología Obesidad y Nutrición (CIBERObn), Instituto Salud Carlos III, Madrid, Spain; Department of Clinical Sciences, School of Medicine, University of Barcelona, Barcelona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0130319PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471115PMC
April 2016

Development of and Recovery from Secondary Hypogonadism in Aging Men: Prospective Results from the EMAS.

J Clin Endocrinol Metab 2015 Aug 22;100(8):3172-82. Epub 2015 May 22.

Sexual Medicine and Andrology Unit (G.R., G.F., M.M.), Department of Experimental Clinical and Biomedical Sciences, University of Florence, 50139 Florence, Italy; Andrology Research Unit (E.L.C., T.A., J.D.F., F.C.W.W.), Centre for Endocrinology and Diabetes, Institute of Human Development, The University of Manchester, Manchester M13 9WL, United Kingdom; Department of Andrology and Endocrinology (L.A., D.V.), Katholieke Universiteit Leuven, B 3000 Leuven, Belgium; Arthritis Research UK Centre for Epidemiology (T.W.O.), Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, Manchester Academic Health Science Centre, University of Manchester and National Institute for Health Research Manchester Musculoskeletal Biomedical Research Unit, Central Manchester National Health Service Foundation Trust, Manchester M13 9WL, United Kingdom; Department of Obstetrics, Gynaecology, and Andrology (G.B.), Albert Szent-György Medical University, H6725 Szeged, Hungary; Department of Medicine (F.F.C.), Santiago de Compostela University, Complejo Hospitalario Universitario de Santiago, Centro de Investigación Biomedical en Red de Fisiopatología Obesidad y Nutricion (CB06/03), Instituto Salud Carlos III, 15076 Santiago de Compostela, Spain; Department of Clinical Biochemistry (B.K.), Istituto Nazionale Biostrutture e Biosistemi (M.M.), Consorzio Interuniversitario, 00136 Rome, Italy; University Hospital of South Manchester, Manchester M13 9WL, United Kingdom; Reproductive Medicine Centre (A.G.), Malmö University Hospital, University of Lund, SE-205 02 Malmö, Sweden; Department of Endocrinology (T.S.H.), Ashford and St Peter's National Health Service Trust, Surrey KT16 0PZ, United Kingdom; Department of Surgery and Cancer (I.T.H.), Institute of Reproductive and Developmental Biology, Imperial College London, London W12 0NN, United Kingdom; Department of Andrology and Reproductive Endocrinology (K.K.), Medical University of Łódź, 90-419 Łódź, Poland; Depar

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http://dx.doi.org/10.1210/jc.2015-1571DOI Listing
August 2015

Leptin resistance in obesity: An epigenetic landscape.

Life Sci 2015 Nov 18;140:57-63. Epub 2015 May 18.

Laboratory of Molecular and Cellular Endocrinology, Instituto de Investigación Sanitaria (IDIS), Complejo Hospitalario Universitario de Santiago (CHUS) and Santiago de Compostela University (USC), Santiago de Compostela, Spain; CIBER Fisiopatología de la Obesidad y la Nutrición (CIBERobn), Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.lfs.2015.05.003DOI Listing
November 2015

Peripheral signals mediate the beneficial effects of gastric surgery in obesity.

Gastroenterol Res Pract 2015 15;2015:560938. Epub 2015 Apr 15.

Grupo Fisiopatología Endocrina, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complexo Hospitalario Universitario de Santiago (CHUS/SERGAS), Travesía Choupana s/n, 15706 Santiago de Compostela, Spain ; CIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Spain.

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http://dx.doi.org/10.1155/2015/560938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413036PMC
May 2015

Regulation of NUCB2/nesfatin-1 production in rat's stomach and adipose tissue is dependent on age, testosterone levels and lactating status.

Mol Cell Endocrinol 2015 Aug 23;411:105-12. Epub 2015 Apr 23.

Grupo Fisiopatología Endocrina, Complexo Hospitalario Universitario de Santiago (CHUS/SERGAS).; CIBER Fisiopatología Obesidad y Nutrición, Instituto de Salud Carlos III, Spain; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2015.04.016DOI Listing
August 2015

Action of obestatin in skeletal muscle repair: stem cell expansion, muscle growth, and microenvironment remodeling.

Mol Ther 2015 Jun 12;23(6):1003-1021. Epub 2015 Mar 12.

Área de Endocrinología Molecular y Celular, Instituto de Investigación Sanitaria de Santiago (IDIS), Complejo Hospitalario Universitario de Santiago (CHUS), Servicio Gallego de Salud (SERGAS), Santiago de Compostela, Spain; CIBER Fisiopatología de la Obesidad y Nutrición, Spain. Electronic address:

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http://dx.doi.org/10.1038/mt.2015.40DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817756PMC
June 2015

Hypopituitarism after traumatic brain injury.

Endocrinol Metab Clin North Am 2015 Mar 4;44(1):151-9. Epub 2014 Nov 4.

Endocrinology Division, Departamento de Medicina, Complejo Hospitalario Universitario de Santiago de Compostela, SERGAS, Universidad de Santiago de Compostela, Santiago de Compostela, Spain; Research Centre in Physiopathology of Obesity and Nutrition, Instituto Salud Carlos III, Santiago de Compostela, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.ecl.2014.10.012DOI Listing
March 2015

Associations between sex steroids and the development of metabolic syndrome: a longitudinal study in European men.

J Clin Endocrinol Metab 2015 Apr 30;100(4):1396-404. Epub 2015 Jan 30.

Department of Clinical and Experimental Medicine (L.A., B.D., D.V.), KU Leuven, Laboratory of Clinical and Experimental Endocrinology, B-3000 Leuven, Belgium; Department of Cellular and Molecular Medicine (L.A., M.R.L., F.C.), KU Leuven, Laboratory of Molecular Endocrinology, B-3000 Leuven, Belgium; Department of Endocrinology (L.A., B.D., D.V.), University Hospitals Leuven, B-3000 Leuven, Belgium; Andrology Research Unit (F.C.W.W., E.L.C., J.D.F., M.K.R.), Endocrinology and Diabetes Research Group, Institute of Human Development, Faculty of Medical and Human Sciences, The University of Manchester, Manchester M13 9WL, United Kingdom; Manchester Royal Infirmary (F.C.W.W.), Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom; Arthritis Research UK Centre of Epidemiology (T.W.O., S.R.P.), The University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom; NIHR Manchester Musculoskeletal Biomedical Research Unit (T.W.O.), Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom; The Endocrinology and Diabetes Research Group (M.K.R.), Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9WL United Kingdom; Manchester Diabetes Centre (M.K.R.), Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom; Department of Clinical and Experimental Medicine (M.R.L.), KU Leuven, Laboratory of Gerontology and Geriatrics, B-3000 Leuven, Belgium; Department of Surgery and Cancer (I.T.H.), Imperial College London, Hammersmith Campus, London W12 ONN, United Kingdom; Department of Endocrinology (T.S.H.), Ashford and St. Peter's NHS Foundation Trust Hospital, Chertsey, Surrey, KT16 0PZ, United Kingdom; Department of Hum

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2014-4184DOI Listing
April 2015