Felicitas Thol

Felicitas Thol

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Felicitas Thol

Felicitas Thol

Publications by authors named "Felicitas Thol"

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Allogeneic stem cell transplantation in patients with myelofibrosis harboring the MPL mutation.

Eur J Haematol 2019 Dec 16;103(6):552-557. Epub 2019 Sep 16.

Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1111/ejh.13318DOI Listing
December 2019

Do next-generation sequencing results drive diagnostic and therapeutic decisions in MDS?

Blood Adv 2019 Nov;3(21):3449-3453

Medical Clinic and Policlinic 1, Hematology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1182/bloodadvances.2018022434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855118PMC
November 2019

Lipid nanoparticle-mediated siRNA delivery for safe targeting of human CML in vivo.

Ann Hematol 2019 Aug 18;98(8):1905-1918. Epub 2019 May 18.

Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Carl-Neuberg Strasse 1, 30625, Hannover, Germany.

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http://dx.doi.org/10.1007/s00277-019-03713-yDOI Listing
August 2019

ASXL1/EZH2 mutations promote clonal expansion of neoplastic HSC and impair erythropoiesis in PMF.

Leukemia 2019 01 15;33(1):99-109. Epub 2018 Jun 15.

Department for Stem Cell Transplantation, University Medical Center Hamburg - Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1038/s41375-018-0159-0DOI Listing
January 2019

Influenza and respiratory syncytial virus screening for the detection of asymptomatically infected patients in hematology and oncology.

GMS Hyg Infect Control 2018 24;13:Doc08. Epub 2018 Sep 24.

Institute for Medical Microbiology and Hospital Epidemiology, Hannover Medical School (MHH), Hannover, Germany.

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http://dx.doi.org/10.3205/dgkh000314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234716PMC
September 2018

Epigenetics in myelodysplastic syndromes.

Semin Cancer Biol 2018 08 2;51:170-179. Epub 2017 Aug 2.

Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1016/j.semcancer.2017.07.009DOI Listing
August 2018

Can we forecast induction failure in acute myeloid leukemia?

Authors:
Felicitas Thol

Haematologica 2018 03;103(3):375-377

Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.3324/haematol.2018.187575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830369PMC
March 2018

An optimized lentiviral vector system for conditional RNAi and efficient cloning of microRNA embedded short hairpin RNA libraries.

Biomaterials 2017 Sep 23;139:102-115. Epub 2017 May 23.

Institute of Experimental Hematology, Hannover Medical School, 30625 Hannover, Germany; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, 30625 Hannover, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2017.05.032DOI Listing
September 2017

Activation of TRKA receptor elicits mastocytosis in mice and is involved in the development of resistance to KIT-targeted therapy.

Oncotarget 2017 Sep 19;8(43):73871-73883. Epub 2017 May 19.

Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.18632/oncotarget.18027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650308PMC
September 2017

A common ancestral DNMT3A-mutated preleukemic clone giving rise to AML and MDS in an adolescent girl.

Leuk Lymphoma 2017 03 28;58(3):718-721. Epub 2016 Nov 28.

e Division of Pediatric Hematology and Oncology, Department of Pediatrics , University Medical Center Freiburg , Freiburg , Germany.

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http://dx.doi.org/10.1080/10428194.2016.1207765DOI Listing
March 2017

Genomic Classification and Prognosis in Acute Myeloid Leukemia.

N Engl J Med 2016 Jun;374(23):2209-2221

Cancer Genome Project, Wellcome Trust Sanger Institute (E.P., M.G., N.D.R., N.B., G.G., P.V.L., I.M., L.M., S.M., S.O., K.R., D.R.J., J.W.T., A.P.B., P.J.C.), and the European Bioinformatics Institute, European Molecular Biology Laboratory (EMBL-EBI) (M.G.), Hinxton, the Centre for Evolution and Cancer, Institute of Cancer Research, London (N.E.P., M.F.G.), and the Department of Haematology, University of Cambridge, Cambridge (N.B.) - all in the United Kingdom; the Departments of Epidemiology and Biostatistics and Cancer Biology, the Center for Molecular Oncology and the Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York (E.P.); the Department of Internal Medicine III, Ulm University, Ulm (L.B., V.I.G., P.P., K.D., R.F.S., H.D.), and the Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover (M.H., F.T., A.G.) - both in Germany; the Division of Hematology, Fondazione IRCCS, Istituto Nazionale dei Tumori, and Department of Oncology and Onco-Hematology, University of Milan, Milan (N.B.); the Department of Human Genetics, University of Leuven, Leuven, Belgium (P.V.L.); and the Department of Pathology, University of Otago, Christchurch, New Zealand (P.G., P.J.C.).

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http://dx.doi.org/10.1056/NEJMoa1516192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979995PMC
June 2016

Clonal Hematopoiesis of Indeterminate Potential.

Dtsch Arztebl Int 2016 May;113(18):317-22

Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School.

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http://dx.doi.org/10.3238/arztebl.2016.0317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961884PMC
May 2016

How I treat refractory and early relapsed acute myeloid leukemia.

Blood 2015 Jul 7;126(3):319-27. Epub 2015 Apr 7.

Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany; and.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-10-55
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http://dx.doi.org/10.1182/blood-2014-10-551911DOI Listing
July 2015

Aberrant splicing of U12-type introns is the hallmark of ZRSR2 mutant myelodysplastic syndrome.

Nat Commun 2015 Jan 14;6:6042. Epub 2015 Jan 14.

1] Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, 12-01, Singapore 117599, Singapore [2] Cedars-Sinai Medical Center, Division of Hematology/Oncology, UCLA School of Medicine, Los Angeles, California 90048, USA [3] National University Cancer Institute, National University Hospital Singapore, Singapore 119228, Singapore.

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http://www.nature.com/articles/ncomms7042
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http://dx.doi.org/10.1038/ncomms7042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349895PMC
January 2015

TET2 mutations in cytogenetically normal acute myeloid leukemia: clinical implications and evolutionary patterns.

Genes Chromosomes Cancer 2014 Oct 5;53(10):824-32. Epub 2014 Jun 5.

INSERM U985, Institut Gustave Roussy, Villejuif, France; Department of Hematology, Oncology, and Tumor Immunology, Charité, Berlin, Germany.

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http://dx.doi.org/10.1002/gcc.22191DOI Listing
October 2014

Gemtuzumab ozogamicin in acute myeloid leukemia revisited.

Expert Opin Biol Ther 2014 Aug 28;14(8):1185-95. Epub 2014 May 28.

Hannover Medical School, Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation , Carl-Neuberg-Str. 1, 30625, Hannover , Germany.

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http://dx.doi.org/10.1517/14712598.2014.922534DOI Listing
August 2014

Lack of noncanonical RAS mutations in cytogenetically normal acute myeloid leukemia.

Ann Hematol 2014 Jun 16;93(6):977-82. Epub 2014 Apr 16.

Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1007/s00277-014-2061-9DOI Listing
June 2014

Prognostic significance of expression levels of stem cell regulators MSI2 and NUMB in acute myeloid leukemia.

Ann Hematol 2013 Mar 12;92(3):315-23. Epub 2012 Dec 12.

Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Germany.

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http://dx.doi.org/10.1007/s00277-012-1637-5DOI Listing
March 2013

Next-generation sequencing for minimal residual disease monitoring in acute myeloid leukemia patients with FLT3-ITD or NPM1 mutations.

Genes Chromosomes Cancer 2012 Jul 27;51(7):689-95. Epub 2012 Mar 27.

Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1002/gcc.21955DOI Listing
July 2012

Update on cytogenetic and molecular changes in myelodysplastic syndromes.

Leuk Lymphoma 2012 Apr 15;53(4):525-36. Epub 2011 Nov 15.

Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany.

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http://www.tandfonline.com/doi/full/10.3109/10428194.2011.61
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http://dx.doi.org/10.3109/10428194.2011.618235DOI Listing
April 2012

FLT3-internal tandem duplication and age are the major prognostic factors in patients with relapsed acute myeloid leukemia with normal karyotype.

Haematologica 2011 May 17;96(5):681-6. Epub 2011 Jan 17.

Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Carl-Neuberg Str. 1, 30625 Hannover, Germany.

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http://dx.doi.org/10.3324/haematol.2010.034074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084914PMC
May 2011

Molecular pathogenesis of acute myeloid leukemia: a diverse disease with new perspectives.

Front Med China 2010 Dec 1;4(4):356-62. Epub 2010 Dec 1.

Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, 30625, Germany.

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http://dx.doi.org/10.1007/s11684-010-0220-5DOI Listing
December 2010

IDH1 mutations in patients with myelodysplastic syndromes are associated with an unfavorable prognosis.

Haematologica 2010 Oct 21;95(10):1668-74. Epub 2010 May 21.

Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Carl-Neuberg Strasse 1, Hannover, Germany.

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http://dx.doi.org/10.3324/haematol.2010.025494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948091PMC
October 2010

Prognostic impact of IDH2 mutations in cytogenetically normal acute myeloid leukemia.

Blood 2010 Jul 26;116(4):614-6. Epub 2010 Apr 26.

Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Carl-Neuberg Strasse 1, Hannover, Germany.

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http://dx.doi.org/10.1182/blood-2010-03-272146DOI Listing
July 2010

Erythrocytes serve as a reservoir for cellular and extracellular sphingosine 1-phosphate.

J Cell Biochem 2010 Apr;109(6):1232-43

Institute for Immunology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hanover, Germany.

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http://dx.doi.org/10.1002/jcb.22507DOI Listing
April 2010

To bleed or not to bleed: what is the factor?

J Hosp Med 2009 Sep;4(7):E43-4

Section of Hospital Medicine, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA.

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http://dx.doi.org/10.1002/jhm.476DOI Listing
September 2009

When childbirth causes reversed hemodialysis and renal failure.

South Med J 2009 Mar;102(3):306-7

Department of Internal Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA.

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http://dx.doi.org/10.1097/SMJ.0b013e318188d72dDOI Listing
March 2009

Therapeutic use of erythropoietin in dermatooncology.

J Dtsch Dermatol Ges 2007 Apr;5(4):280-5

Department of Dermatology and Venereology, Skin Tumor Center, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1111/j.1610-0387.2007.06203.xDOI Listing
April 2007