Fei Mao

Fei Mao

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Systematic Exposition of Mesenchymal Stem Cell for Inflammatory Bowel Disease and Its Associated Colorectal Cancer.

Biomed Res Int 2018 26;2018:9652817. Epub 2018 Dec 26.

Key Laboratory of Medical Science and Laboratory Medicine of Jiangsu Province, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, China.

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http://dx.doi.org/10.1155/2018/9652817DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327253PMC
May 2019

Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice.

Acta Pharmacol Sin 2019 Apr 18. Epub 2019 Apr 18.

Center for Drug Safety Evaluation and Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.

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http://dx.doi.org/10.1038/s41401-019-0220-1DOI Listing
April 2019

miR‑498 inhibits the growth and metastasis of liver cancer by targeting ZEB2.

Oncol Rep 2019 Mar 21;41(3):1638-1648. Epub 2018 Dec 21.

Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.

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http://www.spandidos-publications.com/10.3892/or.2018.6948
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http://dx.doi.org/10.3892/or.2018.6948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365765PMC
March 2019

Compound heterozygous mutations in PARK2 causing early-onset Parkinson disease: A case report.

Medicine (Baltimore) 2019 Feb;98(5):e14228

Department of Neurology, Qianfoshan Hospital, Shandong University, Jinan, Shandong, China.

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http://dx.doi.org/10.1097/MD.0000000000014228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380659PMC
February 2019

ZNF433 positively regulates the beta-catenin/ TCF pathway in prostate cancer and enhances the tumorigenicity of cancer cells.

Onco Targets Ther 2019 1;12:1031-1039. Epub 2019 Feb 1.

Department of Urology, Huai'an First People's Hospital, Nanjing Medical University, Huai'an 223300, Jiangsu, People's Republic of China,

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http://dx.doi.org/10.2147/OTT.S178150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362961PMC
February 2019

COL6A1 mutation leading to Bethlem myopathy with recurrent hematuria: a case report.

BMC Neurol 2019 Feb 26;19(1):32. Epub 2019 Feb 26.

Department of Neurology, Affiliated Qianfoshan Hospital of Shandong University, NO.16766, Jingshi Road, Shandong, Jinan, 250014, CN, China.

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http://dx.doi.org/10.1186/s12883-019-1263-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390614PMC
February 2019

Emerging Role of Mesenchymal Stem Cell-derived Exosomes in Regenerative Medicine.

Curr Stem Cell Res Ther 2019 Feb 27. Epub 2019 Feb 27.

Zhenjiang Key Laboratory of High Technology Research on Exosomes Foundation and Transformation Application, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu. China.

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http://dx.doi.org/10.2174/1574888X14666190228103230DOI Listing
February 2019

Rational Design of Novel Selective Dual-Target Inhibitors of Acetylcholinesterase and Monoamine Oxidase B as Potential Anti-Alzheimer's Disease Agents.

ACS Chem Neurosci 2019 Jan 29;10(1):482-496. Epub 2018 Aug 29.

State Key Laboratory of Bioreactor Engineering , East China University of Science and Technology , 130 Mei Long Road , Shanghai 200237 , China.

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http://dx.doi.org/10.1021/acschemneuro.8b00357DOI Listing
January 2019

Urinary measurement of circulating tumor DNA for treatment monitoring and prognosis of metastatic colorectal cancer patients.

Clin Chem Lab Med 2018 Dec;57(2):268-275

Center for Laboratory Medicine, Maternal and Child Health Hospital of Hainan Province, Longkun Road 75, 570206 Haikou, P.R. China.

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http://dx.doi.org/10.1515/cclm-2017-0675DOI Listing
December 2018

NOL8, the binding protein for beta-catenin, promoted the growth and migration of prostate cancer cells.

Chem Biol Interact 2018 Oct 18;294:40-47. Epub 2018 Aug 18.

Department of Urology, The Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University, 6 Beijing Road West, Huai'an, 223300, Jiangsu, People's Republic of China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00092797183016
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http://dx.doi.org/10.1016/j.cbi.2018.08.019DOI Listing
October 2018

SALL4 activates TGF-β/SMAD signaling pathway to induce EMT and promote gastric cancer metastasis.

Cancer Manag Res 2018 10;10:4459-4470. Epub 2018 Oct 10.

Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, China,

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http://dx.doi.org/10.2147/CMAR.S177373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188178PMC
October 2018

The metal distribution and the change of physiological and biochemical process in soybean and mung bean plants under heavy metal stress.

Int J Phytoremediation 2018 Sep;20(11):1113-1120

a School of Pharmacy, Xi'an Jiaotong University , Xi'an , China.

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http://dx.doi.org/10.1080/15226514.2017.1365346DOI Listing
September 2018

Human Mesenchymal Stem Cell Derived Exosomes Alleviate Type 2 Diabetes Mellitus by Reversing Peripheral Insulin Resistance and Relieving β-Cell Destruction.

ACS Nano 2018 Aug 7;12(8):7613-7628. Epub 2018 Aug 7.

Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, Institute of Stem Cell, School of Medicine , Jiangsu University , Zhenjiang , Jiangsu 212013 , China.

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http://pubs.acs.org/doi/10.1021/acsnano.7b07643
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http://dx.doi.org/10.1021/acsnano.7b07643DOI Listing
August 2018

Discovery of novel Syk/PDGFR-α/c-Kit inhibitors as multi-targeting drugs to treat rheumatoid arthritis.

Bioorg Med Chem 2018 08 22;26(15):4375-4381. Epub 2018 Jun 22.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science & Technology, 130 Meilong Road, Shanghai 200237, People's Republic of China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09680896183066
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http://dx.doi.org/10.1016/j.bmc.2018.06.029DOI Listing
August 2018

Novel Tadalafil Derivatives Ameliorates Scopolamine-Induced Cognitive Impairment in Mice via Inhibition of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5).

ACS Chem Neurosci 2018 Jul 17;9(7):1625-1636. Epub 2018 Apr 17.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy , East China University of Science and Technology , 130 Mei Long Road , Shanghai 200237 , China.

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http://dx.doi.org/10.1021/acschemneuro.8b00014DOI Listing
July 2018

Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairment.

Bioorg Med Chem 2018 07 18;26(12):3117-3125. Epub 2018 Apr 18.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237, China. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2018.04.037DOI Listing
July 2018

Exosomes derived from human umbilical cord mesenchymal stem cells alleviate inflammatory bowel disease in mice through ubiquitination.

Am J Transl Res 2018 15;10(7):2026-2036. Epub 2018 Jul 15.

Key Laboratory of Medical Science and Laboratory Medicine of Jiangsu Province, School of Medicine, Jiangsu University Zhenjiang 212013, Jiangsu, P. R. China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079129PMC
July 2018

Biodegradation of sulfonamides by Shewanella oneidensis MR-1 and Shewanella sp. strain MR-4.

Biodegradation 2018 04 4;29(2):129-140. Epub 2018 Jan 4.

School of Resources and Environment, Anhui Agricultural University, Hefei, 230036, China.

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http://dx.doi.org/10.1007/s10532-017-9818-5DOI Listing
April 2018

Detection of relationships between SUDOSCAN with estimated glomerular filtration rate (eGFR) in Chinese patients with type 2 diabetes.

Diabetes Res Clin Pract 2018 Apr 3;138:113-118. Epub 2018 Feb 3.

Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, China; Department of Endocrinology and Metabolism, Jing'an District Center Hospital of Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.diabres.2018.01.036DOI Listing
April 2018

Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Relieve Inflammatory Bowel Disease in Mice.

Biomed Res Int 2017 15;2017:5356760. Epub 2017 May 15.

Key Laboratory of Medical Science and Laboratory Medicine of Jiangsu Province, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, China.

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https://www.hindawi.com/journals/bmri/2017/5356760/
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http://dx.doi.org/10.1155/2017/5356760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447283PMC
March 2018

Discovery of Potent Benzocycloalkane Derived Diapophytoene Desaturase Inhibitors with an Enhanced Safety Profile for the Treatment of MRSA, VISA, and LRSA Infections.

ACS Infect Dis 2018 03 12;4(3):208-217. Epub 2018 Feb 12.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy , East China University of Science and Technology , 130 Meilong Road , Xuhui District, Shanghai , 200237 , China.

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http://dx.doi.org/10.1021/acsinfecdis.7b00259DOI Listing
March 2018

Novel Staphyloxanthin Inhibitors with Improved Potency against Multidrug Resistant .

ACS Med Chem Lett 2018 Mar 22;9(3):233-237. Epub 2018 Feb 22.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China.

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http://dx.doi.org/10.1021/acsmedchemlett.7b00501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846034PMC
March 2018

Ubiquitination regulation of inflammatory responses through NF-κB pathway.

Am J Transl Res 2018 15;10(3):881-891. Epub 2018 Mar 15.

Key Laboratory of Medical Science and Laboratory Medicine of Jiangsu Province, School of Medicine, Jiangsu UniversityZhenjiang 212013, Jiangsu, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883129PMC
March 2018

Human Umbilical Cord MSC-Derived Exosomes Suppress the Development of CCl-Induced Liver Injury through Antioxidant Effect.

Stem Cells Int 2018 4;2018:6079642. Epub 2018 Mar 4.

Liver Disease and Cancer Institute, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.

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http://dx.doi.org/10.1155/2018/6079642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857330PMC
March 2018

The Association between Serum Bilirubin Level and Electrochemical Skin Conductance in Chinese Patients with Type 2 Diabetes.

Int J Endocrinol 2018 7;2018:6253170. Epub 2018 Mar 7.

Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1155/2018/6253170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863353PMC
March 2018

3,3'-Diindolylmethane stimulates exosomal Wnt11 autocrine signaling in human umbilical cord mesenchymal stem cells to enhance wound healing.

Theranostics 2017 10;7(6):1674-1688. Epub 2017 Apr 10.

Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, China.

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http://dx.doi.org/10.7150/thno.18082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436520PMC
February 2018

Design, Synthesis, and Biological Evaluation of Orally Available First-Generation Dual-Target Selective Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) for the Treatment of Alzheimer's Disease.

ACS Chem Neurosci 2018 02 9;9(2):328-345. Epub 2017 Nov 9.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology , 130 Mei Long Road, Shanghai 200237, China.

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http://dx.doi.org/10.1021/acschemneuro.7b00345DOI Listing
February 2018

Discovery of novel piperonyl derivatives as diapophytoene desaturase inhibitors for the treatment of methicillin-, vancomycin- and linezolid-resistant Staphylococcus aureus infections.

Eur J Med Chem 2018 Feb 29;145:235-251. Epub 2017 Dec 29.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2017.12.090DOI Listing
February 2018

HucMSC exosome-transported 14-3-3ζ prevents the injury of cisplatin to HK-2 cells by inducing autophagy in vitro.

Cytotherapy 2018 01 21;20(1):29-44. Epub 2017 Sep 21.

Key Laboratory of Laboratory Medicine of Jiangsu Province, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2017.08.002DOI Listing
January 2018

A novel method to isolate mesenchymal stem cells from mouse umbilical cord.

Mol Med Rep 2018 Jan 3;17(1):861-869. Epub 2017 Nov 3.

Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.

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http://dx.doi.org/10.3892/mmr.2017.7950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780165PMC
January 2018

Discovery of novel propargylamine-modified 4-aminoalkyl imidazole substituted pyrimidinylthiourea derivatives as multifunctional agents for the treatment of Alzheimer's disease.

Eur J Med Chem 2018 Jan 10;143:33-47. Epub 2017 Aug 10.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2017.08.025DOI Listing
January 2018

Discovery of novel purine nucleoside derivatives as phosphodiesterase 2 (PDE2) inhibitors: Structure-based virtual screening, optimization and biological evaluation.

Bioorg Med Chem 2018 01 14;26(1):119-133. Epub 2017 Nov 14.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237, China. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2017.11.022DOI Listing
January 2018

Novel Terminal Bipheny-Based Diapophytoene Desaturases (CrtN) Inhibitors as Anti-MRSA/VISR/LRSA Agents with Reduced hERG Activity.

J Med Chem 2018 01 28;61(1):224-250. Epub 2017 Dec 28.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology , Shanghai 200237, China.

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http://pubs.acs.org/doi/10.1021/acs.jmedchem.7b01300
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http://dx.doi.org/10.1021/acs.jmedchem.7b01300DOI Listing
January 2018

HucMSC exosomes-delivered 14-3-3ζ enhanced autophagy via modulation of ATG16L in preventing cisplatin-induced acute kidney injury.

Am J Transl Res 2018 15;10(1):101-113. Epub 2018 Jan 15.

Key Laboratory of Laboratory Medicine of Jiangsu Province, School of Medicine, Jiangsu UniversityZhenjiang, Jiangsu, P. R. China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801350PMC
January 2018

Novel Vilazodone-Tacrine Hybrids as Potential Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease Accompanied with Depression: Design, Synthesis, and Biological Evaluation.

ACS Chem Neurosci 2017 12 19;8(12):2708-2721. Epub 2017 Sep 19.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology , 130 Mei Long Road, Shanghai 200237, China.

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http://dx.doi.org/10.1021/acschemneuro.7b00259DOI Listing
December 2017

Discovery of new antimalarial agents: Second-generation dual inhibitors against FP-2 and PfDHFR via fragments assembely.

Bioorg Med Chem 2017 12 16;25(24):6467-6478. Epub 2017 Oct 16.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09680896173160
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http://dx.doi.org/10.1016/j.bmc.2017.10.017DOI Listing
December 2017

Actein induces autophagy and apoptosis in human bladder cancer by potentiating ROS/JNK and inhibiting AKT pathways.

Oncotarget 2017 Dec 1;8(68):112498-112515. Epub 2017 Nov 1.

Branch of Raw Material and Natural Products, Far East Biological Products Co. LTD., Nanjing 210009, China.

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http://dx.doi.org/10.18632/oncotarget.22274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762528PMC
December 2017

YAP signaling in gastric cancer-derived mesenchymal stem cells is critical for its promoting role in cancer progression.

Int J Oncol 2017 Oct 23;51(4):1055-1066. Epub 2017 Aug 23.

Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.

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https://www.spandidos-publications.com/10.3892/ijo.2017.4101
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http://dx.doi.org/10.3892/ijo.2017.4101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592864PMC
October 2017

ALOX15 as a suppressor of inflammation and cancer: Lost in the link.

Prostaglandins Other Lipid Mediat 2017 09 13;132:77-83. Epub 2017 Jan 13.

Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States. Electronic address:

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http://dx.doi.org/10.1016/j.prostaglandins.2017.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509529PMC
September 2017

miR-374 mediates the malignant transformation of gastric cancer-associated mesenchymal stem cells in an experimental rat model.

Oncol Rep 2017 Sep 18;38(3):1473-1481. Epub 2017 Jul 18.

Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.

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http://dx.doi.org/10.3892/or.2017.5831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549036PMC
September 2017

Identification of a novel YAP-14-3-3ζ negative feedback loop in gastric cancer.

Oncotarget 2017 Sep 19;8(42):71894-71910. Epub 2017 May 19.

Key Laboratory of Laboratory Medicine of Jiangsu Province, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, P.R. China.

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http://dx.doi.org/10.18632/oncotarget.18011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641098PMC
September 2017

Neutrophil-to-lymphocyte ratio is associated with diabetic peripheral neuropathy in type 2 diabetes patients.

Diabetes Res Clin Pract 2017 Aug 12;130:90-97. Epub 2017 May 12.

Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, 12# Middle Wulumuqi Road, Shanghai 200040, China. Electronic address:

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http://dx.doi.org/10.1016/j.diabres.2017.05.008DOI Listing
August 2017

SUDOSCAN, an effective tool for screening chronic kidney disease in patients with type 2 diabetes.

Exp Ther Med 2017 Aug 27;14(2):1343-1350. Epub 2017 Jun 27.

Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China.

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http://dx.doi.org/10.3892/etm.2017.4689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525651PMC
August 2017

Association of SUDOSCAN Values with Vibration Perception Threshold in Chinese Patients with Type 2 Diabetes Mellitus.

Int J Endocrinol 2017 20;2017:8435252. Epub 2017 Jul 20.

Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1155/2017/8435252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541789PMC
July 2017

Human umbilical cord mesenchymal stem cells alleviate inflammatory bowel disease through the regulation of 15-LOX-1 in macrophages.

Biotechnol Lett 2017 Jun 3;39(6):929-938. Epub 2017 Mar 3.

Key Laboratory of Medical Science and Laboratory Medicine of Jiangsu Province, School of MedicineJiangsu University, 301 Xuefu Road, Zhenjiang, 212013, Jiangsu, People's Republic of China.

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http://dx.doi.org/10.1007/s10529-017-2315-4DOI Listing
June 2017

Mesenchymal stem cells and their therapeutic applications in inflammatory bowel disease.

Oncotarget 2017 Jun;8(23):38008-38021

Key Laboratory of Medical Science and Laboratory Medicine of Jiangsu Province, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, P.R. China.

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http://dx.doi.org/10.18632/oncotarget.16682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514968PMC
June 2017

Cancer stemness and metastatic potential of the novel tumor cell line K3: an inner mutated cell of bone marrow-derived mesenchymal stem cells.

Oncotarget 2017 Jun;8(24):39522-39533

Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, P. R. China.

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http://dx.doi.org/10.18632/oncotarget.17133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503629PMC
June 2017

Discovery of Potent, Selective Stem Cell Factor Receptor/Platelet Derived Growth Factor Receptor Alpha (c-KIT/PDGFRα) Dual Inhibitor for the Treatment of Imatinib-Resistant Gastrointestinal Stromal Tumors (GISTs).

J Med Chem 2017 06 7;60(12):5099-5119. Epub 2017 Jun 7.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology , Shanghai 200237, China.

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http://dx.doi.org/10.1021/acs.jmedchem.7b00468DOI Listing
June 2017

Crosstalk between mesenchymal stem cells and macrophages in inflammatory bowel disease and associated colorectal cancer.

Contemp Oncol (Pozn) 2017 30;21(2):91-97. Epub 2017 Jun 30.

Key Laboratory of Medical Science and Laboratory Medicine of Jiangsu Province, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, P.R. China.

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https://www.termedia.pl/doi/10.5114/wo.2017.68616
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http://dx.doi.org/10.5114/wo.2017.68616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611497PMC
June 2017

Development of the First Generation of Disulfide-Based Subtype-Selective and Potent Covalent Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors.

J Med Chem 2017 03 6;60(6):2227-2244. Epub 2017 Mar 6.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology , Shanghai 200237, China.

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http://dx.doi.org/10.1021/acs.jmedchem.6b01245DOI Listing
March 2017

hucMSC Exosome-Derived GPX1 Is Required for the Recovery of Hepatic Oxidant Injury.

Mol Ther 2017 02 6;25(2):465-479. Epub 2017 Jan 6.

Liver Disease and Cancer Institute, School of Medicine, Jiangsu University, 212013 Zhenjiang, Jiangsu, People's Republic of China; Key Laboratory of Laboratory Medicine of Jiangsu Province, School of Medicine, Jiangsu University, 212013 Zhenjiang, Jiangsu, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2016.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368592PMC
February 2017

C-peptide is independent associated with diabetic peripheral neuropathy: a community-based study.

Diabetol Metab Syndr 2017 13;9:12. Epub 2017 Feb 13.

Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, 12 Middle Urumqi Road, Shanghai, 200040 China.

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http://dx.doi.org/10.1186/s13098-017-0208-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307841PMC
February 2017

Metastasis regulation by PPARD expression in cancer cells.

JCI Insight 2017 01 12;2(1):e91419. Epub 2017 Jan 12.

Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1172/jci.insight.91419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214933PMC
January 2017

Exosomes from Human Umbilical Cord Mesenchymal Stem Cells: Identification, Purification, and Biological Characteristics.

Stem Cells Int 2016 25;2016:1929536. Epub 2016 Dec 25.

Key Laboratory of Laboratory Medicine of Jiangsu Province, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China; The Affiliated Hospital, Jiangsu University, Zhenjiang, Jiangsu 212000, China.

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http://dx.doi.org/10.1155/2016/1929536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220513PMC
December 2016

MicroRNA-146b, a Sensitive Indicator of Mesenchymal Stem Cell Repair of Acute Renal Injury.

Stem Cells Transl Med 2016 10 8;5(10):1406-1415. Epub 2016 Jul 8.

Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, People's Republic of China

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http://dx.doi.org/10.5966/sctm.2015-0355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031179PMC
October 2016

Regulation of structural and functional synapse density by L-threonate through modulation of intraneuronal magnesium concentration.

Neuropharmacology 2016 09 10;108:426-39. Epub 2016 May 10.

School of Medicine, Tsinghua University, Beijing, 100084, China; Neurocentria, Inc., Fremont, CA 94538, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2016.05.006DOI Listing
September 2016

Development of Multifunctional Pyrimidinylthiourea Derivatives as Potential Anti-Alzheimer Agents.

J Med Chem 2016 Sep 6;59(18):8326-44. Epub 2016 Sep 6.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology , 130 Mei Long Road, Shanghai 200237, China.

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http://dx.doi.org/10.1021/acs.jmedchem.6b00636DOI Listing
September 2016

Melting Point Distribution Analysis of Globally Approved and Discontinued Drugs: A Research for Improving the Chance of Success of Drug Design and Discovery.

ChemistryOpen 2016 Aug 21;5(4):357-68. Epub 2016 Mar 21.

Shanghai Key Laboratory of New Drug Design School of Pharmacy East China University of Science and Technology 130 Mei Long Road Shanghai 200237 P. R. China.

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http://dx.doi.org/10.1002/open.201600015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981057PMC
August 2016

Effect on Electron Structure and Magneto-Optic Property of Heavy W-Doped Anatase TiO2.

PLoS One 2015 8;10(5):e0122620. Epub 2015 May 8.

School of Material Science and Engineering, Beihang University, Beijing, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122620PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425667PMC
April 2016

Bufexamac ameliorates LPS-induced acute lung injury in mice by targeting LTA4H.

Sci Rep 2016 04 29;6:25298. Epub 2016 Apr 29.

Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, Shanghai 200241, China.

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http://www.nature.com/articles/srep25298
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http://dx.doi.org/10.1038/srep25298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850449PMC
April 2016

Anti-cancer drug 3,3'-diindolylmethane activates Wnt4 signaling to enhance gastric cancer cell stemness and tumorigenesis.

Oncotarget 2016 Mar;7(13):16311-24

Key Laboratory of Laboratory Medicine of Jiangsu Province, The Affiliated Hospital, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, P. R. China.

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http://dx.doi.org/10.18632/oncotarget.7684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941316PMC
March 2016

miR-155-5p inhibition promotes the transition of bone marrow mesenchymal stem cells to gastric cancer tissue derived MSC-like cells via NF-κB p65 activation.

Oncotarget 2016 Mar;7(13):16567-80

Key Laboratory of Medical Science and Laboratory Medicine of Jiangsu Province, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.

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http://dx.doi.org/10.18632/oncotarget.7767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941335PMC
March 2016

Lipopolysaccharide Compromises Human Sperm Function by Reducing Intracellular cAMP.

Tohoku J Exp Med 2016 02;238(2):105-12

Department of Urology, Xiangyang Hospital, Hubei University of Medicine.

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http://dx.doi.org/10.1620/tjem.238.105DOI Listing
February 2016

A Metal-free Approach to 3-Aryl-3-hydroxy-2-oxindoles by Treatment of 3-Acyloxy-2-oxindoles with Diaryliodonium Salts.

Chem Asian J 2016 Jan 3;11(2):226-30. Epub 2015 Nov 3.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.

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http://dx.doi.org/10.1002/asia.201500854DOI Listing
January 2016

Novel mutation of SLC20A2 in a Chinese family with primary familial brain calcification.

J Neurol Sci 2016 Jan 23;360:1-3. Epub 2015 Nov 23.

Department of Neurology, Qianfoshan Hospital, Shandong University, Jinan 250014, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0022510X153004
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http://dx.doi.org/10.1016/j.jns.2015.11.036DOI Listing
January 2016

Chemical Structure-Related Drug-Like Criteria of Global Approved Drugs.

Molecules 2016 Jan 12;21(1):75. Epub 2016 Jan 12.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Mei Long Road, 200237 Shanghai, China.

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http://dx.doi.org/10.3390/molecules21010075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273477PMC
January 2016

Tacrine-propargylamine derivatives with improved acetylcholinesterase inhibitory activity and lower hepatotoxicity as a potential lead compound for the treatment of Alzheimer's disease.

J Enzyme Inhib Med Chem 2015 Dec 20;30(6):995-1001. Epub 2015 Mar 20.

a Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University , Guangzhou , China .

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http://dx.doi.org/10.3109/14756366.2014.1003212DOI Listing
December 2015

Study of GABA in Healthy Volunteers: Pharmacokinetics and Pharmacodynamics.

Front Pharmacol 2015 10;6:260. Epub 2015 Nov 10.

Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University Shanghai, China ; Division of Endocrinology and Metabolism, The Keenan Research Centre in the Li Ka Shing Knowledge Institute, St. Michael's Hospital Toronto, ON, Canada ; Department of Physiology and Medicine, University of Toronto ON, Canada.

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http://dx.doi.org/10.3389/fphar.2015.00260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639630PMC
November 2015

The role of 15-LOX-1 in colitis and colitis-associated colorectal cancer.

Inflamm Res 2015 Sep 21;64(9):661-9. Epub 2015 Jul 21.

School of Medicine, Jiangsu University, 301 Xuefu Road, Zhenjiang, 212013, Jiangsu, China,

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http://link.springer.com/content/pdf/10.1007%2Fs00011-015-08
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http://link.springer.com/10.1007/s00011-015-0852-7
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September 2015

Policresulen, a novel NS2B/NS3 protease inhibitor, effectively inhibits the replication of DENV2 virus in BHK-21 cells.

Acta Pharmacol Sin 2015 Sep 17;36(9):1126-36. Epub 2015 Aug 17.

CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.

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http://www.nature.com/articles/aps201556
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http://dx.doi.org/10.1038/aps.2015.56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561973PMC
September 2015

Discovery of benzylidene derivatives as potent Syk inhibitors: synthesis, SAR analysis, and biological evaluation.

Arch Pharm (Weinheim) 2015 Jul 1;348(7):463-74. Epub 2015 Jun 1.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai, China.

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http://dx.doi.org/10.1002/ardp.201500096DOI Listing
July 2015

Activation of mesenchymal stem cells by macrophages prompts human gastric cancer growth through NF-κB pathway.

PLoS One 2014 13;9(5):e97569. Epub 2014 May 13.

School of Medical Science and Laboratory Medicine, Jiangsu University Zhenjiang, Jiangsu, China; The Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0097569PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019592PMC
June 2015

15-Lipoxygenase-1 suppression of colitis-associated colon cancer through inhibition of the IL-6/STAT3 signaling pathway.

FASEB J 2015 Jun 24;29(6):2359-70. Epub 2015 Feb 24.

Departments of *Gastrointestinal Medical Oncology, Pathology, and Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; and School of Medical Science and Laboratory Medicine, Jiangsu University, Zhenjiang, Jiangsu, People's Republic of China

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http://dx.doi.org/10.1096/fj.14-264515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447220PMC
June 2015

Discovery of Novel Small Molecule Anti-HCV Agents via the CypA Inhibitory Mechanism Using O-Acylation-Directed Lead Optimization.

Molecules 2015 Jun 4;20(6):10342-59. Epub 2015 Jun 4.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237, China.

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http://dx.doi.org/10.3390/molecules200610342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272715PMC
June 2015

Design, synthesis, and biological evaluation of benzoselenazole-stilbene hybrids as multi-target-directed anti-cancer agents.

Eur J Med Chem 2015 May 14;95:220-9. Epub 2015 Mar 14.

Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2015.03.030DOI Listing
May 2015

Prolonged adjuvant capecitabine chemotherapy improved survival of stage IIIA gastric cancer after D2 gastrectomy.

Biomed Pharmacother 2015 May 2;72:140-3. Epub 2015 Apr 2.

Department of General Surgery and Molecular Surgery, First People's Hospital Affiliated to Huzhou University Medical College, Huzhou, Zhejiang Province, China.

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http://dx.doi.org/10.1016/j.biopha.2015.03.003DOI Listing
May 2015

Zebrafish cul4a, but not cul4b, modulates cardiac and forelimb development by upregulating tbx5a expression.

Hum Mol Genet 2015 Feb 30;24(3):853-64. Epub 2014 Sep 30.

The Key Laboratory of Experimental Teratology, Ministry of Education and Institute of Molecular Medicine and Genetics, Shandong University School of Medicine, Jinan, Shandong 250012, China

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http://dx.doi.org/10.1093/hmg/ddu503DOI Listing
February 2015

Identification and functional analysis of a SLC33A1: c.339T>G (p.Ser113Arg) variant in the original SPG42 family.

Hum Mutat 2015 Feb;36(2):240-9

The Key Laboratory of Experimental Teratology, Ministry of Education and Department of Genetics, Shandong University School of Medicine, Jinan, Shandong, 250012, China.

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http://dx.doi.org/10.1002/humu.22732DOI Listing
February 2015

Design, synthesis, and evaluation of multitarget-directed selenium-containing clioquinol derivatives for the treatment of Alzheimer's disease.

ACS Chem Neurosci 2014 Oct 22;5(10):952-62. Epub 2014 Aug 22.

Institute of Drug Synthesis and Pharmaceutical Processing, School of Pharmaceutical Sciences, Sun Yat-sen University , Guangzhou 510006, China.

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http://dx.doi.org/10.1021/cn500119gDOI Listing
October 2014

Discovery of new imidazole derivatives containing the 2,4-dienone motif with broad-spectrum antifungal and antibacterial activity.

Molecules 2014 Sep 29;19(10):15653-72. Epub 2014 Sep 29.

Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237, China.

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http://www.mdpi.com/1420-3049/19/10/15653
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http://dx.doi.org/10.3390/molecules191015653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271775PMC
September 2014

Spleen-preserving distal pancreatectomy or distal pancreatectomy with splenectomy?: Perioperative and patient-reported outcome analysis.

J Clin Gastroenterol 2014 Aug;48(7):e62-6

Department of Hepatobiliary Surgery, First People's Hospital affiliated to Huzhou University Medical College, Huzhou, Zhejiang Province, China.

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http://dx.doi.org/10.1097/MCG.0000000000000021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222703PMC
August 2014

New multi-target-directed small molecules against Alzheimer's disease: a combination of resveratrol and clioquinol.

Org Biomol Chem 2014 Aug;12(31):5936-44

School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.

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http://dx.doi.org/10.1039/c4ob00998cDOI Listing
August 2014

Cytomegalovirus retinitis in patients with AIDS before and after introduction of HAART in China.

Eur J Ophthalmol 2014 Mar-Apr;24(2):209-15. Epub 2013 Sep 5.

2 Department of Ophthalmology, Beijing Di Tan Hospital, Capital Medical University, Beijing - China.

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http://dx.doi.org/10.5301/ejo.5000354DOI Listing
July 2014

15-LOX-1 suppression of hypoxia-induced metastatic phenotype and HIF-1α expression in human colon cancer cells.

Cancer Med 2014 Jun 15;3(3):472-84. Epub 2014 Mar 15.

Department of Clinical Cancer, The University of Texas MD Anderson Cancer Center, Houston, Texas, 77030.

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http://dx.doi.org/10.1002/cam4.222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101738PMC
June 2014

Mouse bone marrow-derived mesenchymal stem cells induce macrophage M2 polarization through the nuclear factor-κB and signal transducer and activator of transcription 3 pathways.

Exp Biol Med (Maywood) 2014 Mar 5;239(3):366-75. Epub 2014 Feb 5.

School of Medical Science and Laboratory Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P. R. China.

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http://dx.doi.org/10.1177/1535370213518169DOI Listing
March 2014

The effects of electron transfer on the energy loss of slow He²⁺, C²⁺, and C⁴⁺ ions penetrating a graphene fragment.

J Phys Condens Matter 2014 Feb 7;26(8):085402. Epub 2014 Feb 7.

The Key Laboratory of Beam Technology and Material Modification of Ministry of Education, College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875, People's Republic of China. Beijing Radiation Center, Beijing 100875, People's Republic of China.

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http://dx.doi.org/10.1088/0953-8984/26/8/085402DOI Listing
February 2014

Palladium-catalyzed cross-dehydrogenative functionalization of C(sp(2))-H Bonds.

Chem Asian J 2014 Jan 2;9(1):26-47. Epub 2013 Oct 2.

State Key Laboratory of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong (Hong Kong), Fax: (+852) 2364-9932; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou (China).

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http://dx.doi.org/10.1002/asia.201300990DOI Listing
January 2014

Novel tacrine-ebselen hybrids with improved cholinesterase inhibitory, hydrogen peroxide and peroxynitrite scavenging activity.

Bioorg Med Chem Lett 2013 Dec 29;23(24):6737-42. Epub 2013 Oct 29.

School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.

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http://dx.doi.org/10.1016/j.bmcl.2013.10.034DOI Listing
December 2013

Electron-ion coupling effects on radiation damage in cubic silicon carbide.

J Phys Condens Matter 2013 Jun 16;25(23):235402. Epub 2013 May 16.

The Key Laboratory of Beam Technology and Material Modification of Ministry of Education, College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875, People's Republic of China.

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http://dx.doi.org/10.1088/0953-8984/25/23/235402DOI Listing
June 2013

Macrophages are involved in the protective role of human umbilical cord-derived stromal cells in renal ischemia-reperfusion injury.

Stem Cell Res 2013 May 29;10(3):405-16. Epub 2013 Jan 29.

School of Medical Science and Laboratory Medicine, Jiangsu University, 301 Xuefu Road, Zhenjiang, Jiangsu 212013, China.

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http://dx.doi.org/10.1016/j.scr.2013.01.005DOI Listing
May 2013