Federico Forneris

Federico Forneris

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Federico Forneris

Federico Forneris

Publications by authors named "Federico Forneris"

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SiMPLOD, a Structure-Integrated Database of Collagen Lysyl Hydroxylase (LH/PLOD) Enzyme Variants.

J Bone Miner Res 2019 Jul 12;34(7):1376-1382. Epub 2019 Mar 12.

The Armenise-Harvard Laboratory of Structural Biology, Department of Biology and Biotechnology, University of Pavia, Pavia, Italy.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/jbmr.3692
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http://dx.doi.org/10.1002/jbmr.3692DOI Listing
July 2019

Structural characterization of the third scavenger receptor cysteine-rich domain of murine neurotrypsin.

Protein Sci 2019 Apr 6;28(4):746-755. Epub 2019 Mar 6.

The Armenise-Harvard Laboratory of Structural Biology, Department of Biology and Biotechnology, University of Pavia, Via Ferrata 9/A, 27100 Pavia, Italy.

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http://dx.doi.org/10.1002/pro.3587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423723PMC
April 2019

A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.

Cell Rep 2019 Apr;27(2):387-399.e7

Department of Biology and Biotechnology "Lazzaro Spallanzani," University of Pavia, via Ferrata 9, 27100 Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.03.061DOI Listing
April 2019

Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3.

Nat Commun 2018 08 8;9(1):3163. Epub 2018 Aug 8.

The Armenise-Harvard Laboratory of Structural Biology, Department of Biology and Biotechnology, University of Pavia, Via Ferrata 9/A, 27100, Pavia, Italy.

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http://dx.doi.org/10.1038/s41467-018-05631-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082870PMC
August 2018

Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses.

Nat Struct Mol Biol 2017 Aug 3;24(8):643-651. Epub 2017 Jul 3.

Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Department of Chemistry, Faculty of Science, Utrecht University, Utrecht, the Netherlands.

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http://dx.doi.org/10.1038/nsmb.3427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773341PMC
August 2017

Autosomal Recessive Keratoderma-Ichthyosis-Deafness (ARKID) Syndrome Is Caused by VPS33B Mutations Affecting Rab Protein Interaction and Collagen Modification.

J Invest Dermatol 2017 04 23;137(4):845-854. Epub 2016 Dec 23.

MRC Laboratory for Molecular Cell Biology, University College London, London, UK; Institute of Child Health, University College London, London, UK; Inherited Metabolic Diseases Unit, Great Ormond Street Hospital, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.12.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358661PMC
April 2017

Expanding the structural biology toolbox with single-molecule holography.

Proc Natl Acad Sci U S A 2017 02 2;114(7):1448-1450. Epub 2017 Feb 2.

Department of Biology and Biotechnology, University of Pavia, 27100 Pavia, Italy

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http://dx.doi.org/10.1073/pnas.1620897114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320977PMC
February 2017

Identifying and Visualizing Macromolecular Flexibility in Structural Biology.

Front Mol Biosci 2016 9;3:47. Epub 2016 Sep 9.

The Armenise-Harvard Laboratory of Structural Biology, Department of Biology and Biotechnology, University of Pavia Pavia, Italy.

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http://dx.doi.org/10.3389/fmolb.2016.00047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016524PMC
September 2016

Structural and biochemical insights into 7β-hydroxysteroid dehydrogenase stereoselectivity.

Proteins 2016 06 6;84(6):859-65. Epub 2016 Apr 6.

Department of Biology and Biotechnology, University of Pavia, via Ferrata 9, Pavia, 27100, Italy.

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http://dx.doi.org/10.1002/prot.25036DOI Listing
June 2016

The Crystal Structure of Burkholderia cenocepacia DfsA Provides Insights into Substrate Recognition and Quorum Sensing Fatty Acid Biosynthesis.

Biochemistry 2016 06 2;55(23):3241-50. Epub 2016 Jun 2.

Department of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia , Via Ferrata 9/A, 27100 Pavia, Italy.

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http://dx.doi.org/10.1021/acs.biochem.6b00178DOI Listing
June 2016

Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode.

EMBO J 2016 05 24;35(10):1133-49. Epub 2016 Mar 24.

Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Department of Chemistry, Faculty of Science Utrecht University, Utrecht, The Netherlands

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http://dx.doi.org/10.15252/embj.201593673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868954PMC
May 2016

8 Demethylation pathways for histone methyllysine residues.

Enzymes 2006 4;24:229-42. Epub 2007 Jun 4.

Dipartimento di Biologia e Genetica per le Scienze Mediche Università di Milano Via Celoria 26 Milano 20133, Italy.

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http://dx.doi.org/10.1016/S1874-6047(06)80010-7DOI Listing
January 2016

The three-dimensional structure of "Lonely Guy" from Claviceps purpurea provides insights into the phosphoribohydrolase function of Rossmann fold-containing lysine decarboxylase-like proteins.

Proteins 2015 Aug 1;83(8):1539-46. Epub 2015 Jul 1.

Centre of the Region Haná for Biotechnological and Agricultural Research, Faculty of Science, Palacký University, Olomouc, 783 71, Czech Republic.

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http://dx.doi.org/10.1002/prot.24835DOI Listing
August 2015

Structures of Wnt-antagonist ZNRF3 and its complex with R-spondin 1 and implications for signaling.

PLoS One 2013 12;8(12):e83110. Epub 2013 Dec 12.

Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Department of Chemistry, Faculty of Science, Utrecht University, Utrecht, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0083110PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861454PMC
March 2015

Large extent of disorder in Adenomatous Polyposis Coli offers a strategy to guard Wnt signalling against point mutations.

PLoS One 2013 9;8(10):e77257. Epub 2013 Oct 9.

Cellular Protein Chemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077257PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793970PMC
June 2014

Ensemble refinement shows conformational flexibility in crystal structures of human complement factor D.

Acta Crystallogr D Biol Crystallogr 2014 Mar 15;70(Pt 3):733-43. Epub 2014 Feb 15.

Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Department of Chemistry, Faculty of Science, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.

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http://dx.doi.org/10.1107/S1399004713032549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949522PMC
March 2014

Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5.

Cell Rep 2013 Jun;3(6):1885-92

Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Department of Chemistry, Faculty of Science, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.celrep.2013.06.009DOI Listing
June 2013

The modular serine proteases of the complement cascade.

Curr Opin Struct Biol 2012 Jun 3;22(3):333-41. Epub 2012 May 3.

Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Department of Chemistry, Faculty of Science, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.sbi.2012.04.001DOI Listing
June 2012

Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.

Cell Rep 2012 Mar 23;1(3):200-7. Epub 2012 Feb 23.

Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Department of Chemistry, Faculty of Science, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.celrep.2012.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314296PMC
March 2012

Structures of C3b in complex with factors B and D give insight into complement convertase formation.

Science 2010 Dec;330(6012):1816-20

Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Department of Chemistry, Faculty of Science, Utrecht University, Padualaan 8, 3584 CH Utrecht, Netherlands.

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http://dx.doi.org/10.1126/science.1195821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087196PMC
December 2010

Crystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organization.

Proc Natl Acad Sci U S A 2009 12 16;106(48):20204-9. Epub 2009 Nov 16.

Department of Experimental Oncology, European Institute of Oncology, Via Adamello 16, 20139 Milan, Italy.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0908485106
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http://dx.doi.org/10.1073/pnas.0908485106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777964PMC
December 2009

New roles of flavoproteins in molecular cell biology: histone demethylase LSD1 and chromatin.

FEBS J 2009 Aug 14;276(16):4304-12. Epub 2009 Jul 14.

Dipartimento di Genetica e Microbiologia, Università di Pavia, Italy.

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http://dx.doi.org/10.1111/j.1742-4658.2009.07142.xDOI Listing
August 2009

A novel mammalian flavin-dependent histone demethylase.

J Biol Chem 2009 Jun 30;284(26):17775-82. Epub 2009 Apr 30.

Dipartimento di Genetica e Microbiologia, Università di Pavia, Via Ferrata 1, 27100 Pavia, Italy.

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http://dx.doi.org/10.1074/jbc.M109.003087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719416PMC
June 2009

Multiple pathways guide oxygen diffusion into flavoenzyme active sites.

Proc Natl Acad Sci U S A 2009 Jun 16;106(26):10603-8. Epub 2009 Jun 16.

Department of Chemistry and Biochemistry and Pharmacology, Center for Theoretical Biological Physics, and Howard Hughes Medical Institute, University of California at San Diego, La Jolla, CA 92093-0365, USA.

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http://dx.doi.org/10.1073/pnas.0903809106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698890PMC
June 2009

ThermoFAD, a Thermofluor-adapted flavin ad hoc detection system for protein folding and ligand binding.

FEBS J 2009 May;276(10):2833-40

Department of Genetics and Microbiology, University of Pavia, Italy.

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http://dx.doi.org/10.1111/j.1742-4658.2009.07006.xDOI Listing
May 2009

Enzymes without borders: mobilizing substrates, delivering products.

Science 2008 Jul;321(5886):213-6

Department of Genetics and Microbiology, University of Pavia, Via Ferrata 1, 27100 Pavia, Italy.

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http://dx.doi.org/10.1126/science.1151118DOI Listing
July 2008

LSD1: oxidative chemistry for multifaceted functions in chromatin regulation.

Trends Biochem Sci 2008 Apr 17;33(4):181-9. Epub 2008 Mar 17.

Dipartimento di Genetica e Microbiologia, Università di Pavia, Via Ferrata 1, Pavia, Italy.

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http://dx.doi.org/10.1016/j.tibs.2008.01.003DOI Listing
April 2008

Structural analysis of the catalytic mechanism and stereoselectivity in Streptomyces coelicolor alditol oxidase.

Biochemistry 2008 Jan 23;47(3):978-85. Epub 2007 Dec 23.

Department of Genetics and Microbiology, University of Pavia, Via Ferrata 1, 27100 Pavia, Italy.

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http://dx.doi.org/10.1021/bi701886tDOI Listing
January 2008

Structural basis of LSD1-CoREST selectivity in histone H3 recognition.

J Biol Chem 2007 Jul 30;282(28):20070-4. Epub 2007 May 30.

Dipartimento di Genetica e Microbiologia, Università di Pavia, Via Ferrata 1, 27100 Pavia, Italy.

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http://www.jbc.org/lookup/doi/10.1074/jbc.C700100200
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http://dx.doi.org/10.1074/jbc.C700100200DOI Listing
July 2007

Crystallization and preliminary X-ray analysis of an alditol oxidase from Streptomyces coelicolor A3(2).

Acta Crystallogr Sect F Struct Biol Cryst Commun 2006 Dec 30;62(Pt 12):1298-300. Epub 2006 Nov 30.

Department of Genetics and Microbiology, University of Pavia, Via Ferrata 1, 27100 Pavia, Italy.

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http://scripts.iucr.org/cgi-bin/paper?S1744309106051128
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http://dx.doi.org/10.1107/S1744309106051128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225352PMC
December 2006

A highly specific mechanism of histone H3-K4 recognition by histone demethylase LSD1.

J Biol Chem 2006 Nov 20;281(46):35289-95. Epub 2006 Sep 20.

Dipartimento di Genetica e Microbiologia, Università di Pavia, via Ferrata 1, 27100 Pavia, Italy.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M607411200
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http://dx.doi.org/10.1074/jbc.M607411200DOI Listing
November 2006

Human histone demethylase LSD1 reads the histone code.

J Biol Chem 2005 Dec 13;280(50):41360-5. Epub 2005 Oct 13.

Dipartimento di Genetica e Microbiologia, Università di Pavia, Via Ferrata 1, Pavia 27100, Italy.

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http://dx.doi.org/10.1074/jbc.M509549200DOI Listing
December 2005

Histone demethylation catalysed by LSD1 is a flavin-dependent oxidative process.

FEBS Lett 2005 Apr;579(10):2203-7

Dipartimento di Genetica e Microbiologia, Università di Pavia, Via Ferrata 1, 27100 Pavia, Italy.

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http://dx.doi.org/10.1016/j.febslet.2005.03.015DOI Listing
April 2005

Phasing protein structures using the group-subgroup relation.

Acta Crystallogr D Biol Crystallogr 2003 Aug 23;59(Pt 8):1435-9. Epub 2003 Jul 23.

Centre of Excellence in Biocrystallography, Department of Chemical Sciences, University of Trieste, Via L. Giorgieri 1, 34127 Trieste, Italy.

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http://dx.doi.org/10.1107/s0907444903012538DOI Listing
August 2003