Publications by authors named "Federica Morano"

53Publications

Systemic doxycycline for pre-emptive treatment of anti-EGFR-related skin toxicity in patients with metastatic colorectal cancer receiving first-line panitumumab-based therapy: a post hoc analysis of the Valentino study.

Authors:
Alessandra Raimondi Salvatore Corallo Sara Lonardi Carlotta Antoniotti Lorenza Rimassa Alessio Amatu Marco Tampellini Patrizia Racca Roberto Murialdo Matteo Clavarezza Alberto Zaniboni Giuseppe Toscano Gianluca Tomasello Fausto Petrelli Lorenzo Antonuzzo Monica Giordano Saverio Cinieri Raffaella Longarini Monica Niger Maria Antista Margherita Ambrosini Filippo Pagani Michele Prisciandaro Giovanni Randon Filippo de Braud Maria Di Bartolomeo Filippo Pietrantonio Federica Morano

Support Care Cancer 2021 Jan 3. Epub 2021 Jan 3.

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Giacomo Venezian 1, 20133, Milan, Italy.

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January 2021

FOLFOXIRI-Bevacizumab or FOLFOX-Panitumumab in Patients with Left-Sided RAS/BRAF Wild-Type Metastatic Colorectal Cancer: A Propensity Score-Based Analysis.

Authors:
Filippo Pietrantonio Giovanni Fucà Daniele Rossini Hans-Joachim Schmoll Johanna C Bendell Federica Morano Carlotta Antoniotti Salvatore Corallo Beatrice Borelli Alessandra Raimondi Federica Marmorino Monica Niger Alessandra Boccaccino Gianluca Masi Sara Lonardi Luca Boni Filippo de Braud Maria Di Bartolomeo Alfredo Falcone Chiara Cremolini

Oncologist 2020 Dec 18. Epub 2020 Dec 18.

Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.

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December 2020

Impact of early tumor shrinkage and depth of response on the outcomes of panitumumab-based maintenance in patients with RAS wild-type metastatic colorectal cancer.

Authors:
Paolo Manca Salvatore Corallo Giovanni Randon Sara Lonardi Chiara Cremolini Lorenza Rimassa Francesca Bergamo Carlotta Antoniotti Valeria Smiroldo Alberto Zaniboni Roberto Murialdo Marco Tampellini Gianluca Tomasello Matteo Clavarezza Patrizia Racca Maria Antista Alessandra Raimondi Michele Prisciandaro Filippo Pagani Federica Palermo Francesca Gabriella Greco Marta Vaiani Maria Di Bartolomeo Filippo de Braud Giuseppina Calareso Federica Morano Filippo Pietrantonio

Eur J Cancer 2020 Dec 12;144:31-40. Epub 2020 Dec 12.

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; Oncology and Hemato-oncology Department, University of Milan, Italy. Electronic address:

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December 2020

AtezoTRIBE: a randomised phase II study of FOLFOXIRI plus bevacizumab alone or in combination with atezolizumab as initial therapy for patients with unresectable metastatic colorectal cancer.

Authors:
Carlotta Antoniotti Beatrice Borelli Daniele Rossini Filippo Pietrantonio Federica Morano Lisa Salvatore Sara Lonardi Federica Marmorino Stefano Tamberi Salvatore Corallo Giampaolo Tortora Francesca Bergamo Di Stefano Brunella Alessandra Boccaccino Elisa Grassi Patrizia Racca Emiliano Tamburini Giuseppe Aprile Roberto Moretto Luca Boni Alfredo Falcone Chiara Cremolini

BMC Cancer 2020 Jul 22;20(1):683. Epub 2020 Jul 22.

Department of Oncology, University Hospital of Pisa, Pisa, Italy.

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July 2020

Health-related quality of life in patients with RAS wild-type metastatic colorectal cancer treated with panitumumab-based first-line treatment strategy: A pre-specified secondary analysis of the Valentino study.

Authors:
Alessandra Raimondi Massimo Di Maio Federica Morano Salvatore Corallo Sara Lonardi Carlotta Antoniotti Lorenza Rimassa Andrea Sartore-Bianchi Marco Tampellini Giuliana Ritorto Roberto Murialdo Matteo Clavarezza Alberto Zaniboni Vincenzo Adamo Gianluca Tomasello Fausto Petrelli Lorenzo Antonuzzo Monica Giordano Saverio Cinieri Raffaella Longarini Francesca Bergamo Monica Niger Maria Antista Giorgia Peverelli Filippo de Braud Maria Di Bartolomeo Filippo Pietrantonio

Eur J Cancer 2020 08 2;135:230-239. Epub 2020 Jul 2.

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy; Oncology and Hemato-oncology Department, University of Milan, Milan, Italy. Electronic address:

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August 2020

Prognostic impact of immune-microenvironment in colorectal liver metastases resected after triplets plus a biologic agent: A pooled analysis of five prospective trials.

Authors:
Roberto Moretto Salvatore Corallo Antonino Belfiore Daniele Rossini Alessandra Boccaccino Sara Lonardi Giovanni Centonze Federica Morano Marco Maria Germani Fotios Loupakis Luca Morelli Lucio Urbani Silvia Brich Federica Marmorino Michele Prisciandaro Giuseppe Aprile Matteo Fassan Umberto Cillo Laura Cattaneo Gabriella Fontanini Filippo De Braud Alfredo Falcone Massimo Milione Filippo Pietrantonio Chiara Cremolini

Eur J Cancer 2020 08 15;135:78-88. Epub 2020 Jun 15.

Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy; Department of Translational Research and New Technology in Medicine and Surgery, University of Pisa, Pisa, Italy. Electronic address:

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August 2020

Systemic Treatment of Patients With Gastrointestinal Cancers During the COVID-19 Outbreak: COVID-19-adapted Recommendations of the National Cancer Institute of Milan.

Authors:
Filippo Pietrantonio Federica Morano Monica Niger Salvatore Corallo Maria Antista Alessandra Raimondi Michele Prisciandaro Filippo Pagani Natalie Prinzi Federico Nichetti Giovanni Randon Martina Torchio Francesca Corti Margherita Ambrosini Federica Palermo Michele Palazzo Lavinia Biamonte Marco Platania Carlo Sposito Maurizio Cosimelli Vincenzo Mazzaferro Sara Pusceddu Chiara Cremolini Filippo de Braud Maria Di Bartolomeo

Clin Colorectal Cancer 2020 09 23;19(3):156-164. Epub 2020 May 23.

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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September 2020

The Pan-Immune-Inflammation Value is a new prognostic biomarker in metastatic colorectal cancer: results from a pooled-analysis of the Valentino and TRIBE first-line trials.

Authors:
Giovanni Fucà Vincenzo Guarini Carlotta Antoniotti Federica Morano Roberto Moretto Salvatore Corallo Federica Marmorino Sara Lonardi Lorenza Rimassa Andrea Sartore-Bianchi Beatrice Borelli Marco Tampellini Sara Bustreo Matteo Claravezza Alessandra Boccaccino Roberto Murialdo Alberto Zaniboni Gianluca Tomasello Fotios Loupakis Vincenzo Adamo Giuseppe Tonini Enrico Cortesi Filippo de Braud Chiara Cremolini Filippo Pietrantonio

Br J Cancer 2020 Aug 19;123(3):403-409. Epub 2020 May 19.

Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.

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August 2020

Efficacy and Safety of Immune Checkpoint Inhibitors in Patients with Microsatellite Instability-High End-Stage Cancers and Poor Performance Status Related to High Disease Burden.

Authors:
Filippo Pietrantonio Fotios Loupakis Giovanni Randon Alessandra Raimondi Massimiliano Salati Dario Trapani Filippo Pagani Ilaria Depetris Giulia Maddalena Federica Morano Salvatore Corallo Michele Prisciandaro Francesca Corti Vincenzo Guarini Alessandro Bocconi Antonio Marra Carmen Belli Andrea Spallanzani Matteo Fassan Sara Lonardi Giuseppe Curigliano Giovanni Fucà Maria Di Bartolomeo Filippo de Braud

Oncologist 2020 Sep 20;25(9):803-809. Epub 2020 May 20.

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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September 2020

Clinical Behavior and Treatment Response of Epstein-Barr Virus-Positive Metastatic Gastric Cancer: Implications for the Development of Future Trials.

Authors:
Salvatore Corallo Giovanni Fucà Federica Morano Massimiliano Salati Andrea Spallanzani Annunziata Gloghini Chiara Costanza Volpi Desirè Viola Trupia Riccardo Lobefaro Vincenzo Guarini Massimo Milione Laura Cattaneo Maria Antista Michele Prisciandaro Alessandra Raimondi Carlo Sposito Vincenzo Mazzaferro Filippo de Braud Filippo Pietrantonio Maria Di Bartolomeo

Oncologist 2020 Sep 30;25(9):780-786. Epub 2020 Apr 30.

Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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September 2020

Immune Profiling of Deficient Mismatch Repair Colorectal Cancer Tumor Microenvironment Reveals Different Levels of Immune System Activation.

Authors:
Riccardo Giannini Gemma Zucchelli Mirella Giordano Clara Ugolini Roberto Moretto Katarzyna Ambryszewska Michele Leonardi Elisa Sensi Federica Morano Filippo Pietrantonio Chiara Cremolini Alfredo Falcone Gabriella Fontanini

J Mol Diagn 2020 05 13;22(5):685-698. Epub 2020 Mar 13.

Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy. Electronic address:

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May 2020

Prognostic and Predictive Value of Microsatellite Instability, Inflammatory Reaction and PD-L1 in Gastric Cancer Patients Treated with Either Adjuvant 5-FU/LV or Sequential FOLFIRI Followed by Cisplatin and Docetaxel: A Translational Analysis from the ITACA-S Trial.

Authors:
Maria Di Bartolomeo Federica Morano Alessandra Raimondi Rosalba Miceli Salvatore Corallo Elena Tamborini Federica Perrone Maria Antista Monica Niger Alessandro Pellegrinelli Giovanni Randon Filippo Pagani Antonia Martinetti Giovanni Fucà Filippo Pietrantonio

Oncologist 2020 03 25;25(3):e460-e468. Epub 2019 Nov 25.

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.

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March 2020

Whole exome sequencing analysis of urine trans-renal tumour DNA in metastatic colorectal cancer patients.

Authors:
Giovanni Crisafulli Benedetta Mussolin Andrea Cassingena Monica Montone Alice Bartolini Ludovic Barault Antonia Martinetti Federica Morano Filippo Pietrantonio Andrea Sartore-Bianchi Salvatore Siena Federica Di Nicolantonio Silvia Marsoni Alberto Bardelli Giulia Siravegna

ESMO Open 2019 11;4(6)

University of Turin, Department of Oncology, Candiolo (TO), Italy

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November 2019

Corrigendum to "Gastric cancer: Translating novels concepts into clinical practice" [Cancer Treatm. Rev. 79C (2019) 101889].

Authors:
Massimiliano Salati Giulia Orsi Elisabeth Smyth Giuseppe Aprile Giordano Beretta Fernando De Vita Maria Di Bartolomeo Valentina Fanotto Sara Lonardi Federica Morano Filippo Pietrantonio Carmine Pinto Lorenza Rimassa Enrico Vasile Caterina Vivaldi Alberto Zaniboni Pina Ziranu Stefano Cascinu

Cancer Treat Rev 2019 12 23;81:101932. Epub 2019 Nov 23.

Department of Medical Oncology, Universita' di Modena e Reggio Emilia, Modena, Italy.

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December 2019

Prognostic and Predictive Value of Microsatellite Instability, Inflammatory Reaction and PD-L1 in Gastric Cancer Patients Treated with Either Adjuvant 5-FU/LV or Sequential FOLFIRI Followed by Cisplatin and Docetaxel: A Translational Analysis from the ITACA-S Trial.

Authors:
Maria Di Bartolomeo Federica Morano Alessandra Raimondi Rosalba Miceli Salvatore Corallo Elena Tamborini Federica Perrone Maria Antista Monica Niger Alessandro Pellegrinelli Giovanni Randon Filippo Pagani Antonia Martinetti Giovanni Fucà Filippo Pietrantonio

Oncologist 2019 Nov 25. Epub 2019 Nov 25.

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.

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November 2019

Capecitabine and Temozolomide versus FOLFIRI in RAS-Mutated, MGMT-Methylated Metastatic Colorectal Cancer.

Authors:
Filippo Pietrantonio Riccardo Lobefaro Maria Antista Sara Lonardi Alessandra Raimondi Federica Morano Stefania Mosconi Lorenza Rimassa Sabina Murgioni Andrea Sartore-Bianchi Gianluca Tomasello Raffaella Longarini Gabriella Farina Fausto Petrelli Stefania Gori Giovanni Randon Salvatore Corallo Filippo Pagani Vincenzo Guarini Federica Palermo Antonia Martinetti Marco Macagno Ludovic Barault Federica Perrone Elena Tamborini Massimo Milione Federica Di Nicolantonio Massimo Di Maio Giovanni Fucà Maria Di Bartolomeo Filippo de Braud

Clin Cancer Res 2020 03 18;26(5):1017-1024. Epub 2019 Nov 18.

Oncology and Hemato-oncology Department, University of Milan, Milan, Italy.

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March 2020

A Comprehensive PDX Gastric Cancer Collection Captures Cancer Cell-Intrinsic Transcriptional MSI Traits.

Authors:
Simona Corso Claudio Isella Sara E Bellomo Maria Apicella Stefania Durando Cristina Migliore Stefano Ughetto Laura D'Errico Silvia Menegon Daniel Moya-Rull Marilisa Cargnelutti Tânia Capelôa Daniela Conticelli Jessica Giordano Tiziana Venesio Antonella Balsamo Caterina Marchiò Maurizio Degiuli Rossella Reddavid Uberto Fumagalli Stefano De Pascale Giovanni Sgroi Emanuele Rausa Gian Luca Baiocchi Sarah Molfino Filippo Pietrantonio Federica Morano Salvatore Siena Andrea Sartore-Bianchi Maria Bencivenga Valentina Mengardo Riccardo Rosati Daniele Marrelli Paolo Morgagni Stefano Rausei Giovanni Pallabazzer Michele De Simone Dario Ribero Silvia Marsoni Antonino Sottile Enzo Medico Paola Cassoni Anna Sapino Eirini Pectasides Aaron R Thorner Anwesha Nag Samantha D Drinan Bruce M Wollison Adam J Bass Silvia Giordano

Cancer Res 2019 11 4;79(22):5884-5896. Epub 2019 Oct 4.

Department of Oncology, University of Torino, Candiolo, Italy.

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November 2019

Negative Hyperselection of Patients With and Wild-Type Metastatic Colorectal Cancer Who Received Panitumumab-Based Maintenance Therapy.

Authors:
Federica Morano Salvatore Corallo Sara Lonardi Alessandra Raimondi Chiara Cremolini Lorenza Rimassa Roberto Murialdo Alberto Zaniboni Andrea Sartore-Bianchi Gianluca Tomasello Patrizia Racca Matteo Clavarezza Vincenzo Adamo Federica Perrone Annunziata Gloghini Elena Tamborini Adele Busico Antonia Martinetti Federica Palermo Fotios Loupakis Massimo Milione Giovanni Fucà Maria Di Bartolomeo Filippo de Braud Filippo Pietrantonio

J Clin Oncol 2019 11 20;37(33):3099-3110. Epub 2019 Sep 20.

Fondazione Instituto di Ricovero e Cura Carattere Scientifico (IRCCS) Istituto Nazionale dei Tumori, Milan, Italy.

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November 2019

Individual Patient Data Meta-Analysis of the Value of Microsatellite Instability As a Biomarker in Gastric Cancer.

Authors:
Filippo Pietrantonio Rosalba Miceli Alessandra Raimondi Young Woo Kim Won Ki Kang Ruth E Langley Yoon Young Choi Kyoung-Mee Kim Matthew Guy Nankivell Federica Morano Andrew Wotherspoon Nicola Valeri Myeong-Cherl Kook Ji Yeong An Heike I Grabsch Giovanni Fucà Sung Hoon Noh Tae Sung Sohn Sung Kim Maria Di Bartolomeo David Cunningham Jeeyun Lee Jae-Ho Cheong Elizabeth Catherine Smyth

J Clin Oncol 2019 12 12;37(35):3392-3400. Epub 2019 Sep 12.

Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.

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December 2019

CK7 and consensus molecular subtypes as major prognosticators in BRAF mutated metastatic colorectal cancer.

Authors:
Fotios Loupakis Paola Biason Alessandra Anna Prete Chiara Cremolini Filippo Pietrantonio Nicoletta Pella Emanuela Dell'Aquila Elisa Sperti Clizia Zichi Rossana Intini Vincenzo Dadduzio Marta Schirripa Francesca Bergamo Carlotta Antoniotti Federica Morano Francesco Cortiula Giovanna De Maglio Lorenza Rimassa Valeria Smiroldo Lorenzo Calvetti Giuseppe Aprile Lisa Salvatore Daniele Santini Giada Munari Roberta Salmaso Vincenza Guzzardo Claudia Mescoli Sara Lonardi Massimo Rugge Vittorina Zagonel Massimo Di Maio Matteo Fassan

Br J Cancer 2019 10 2;121(7):593-599. Epub 2019 Sep 2.

Surgical Pathology & Cytopathology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy.

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October 2019

Gastric cancer: Translating novels concepts into clinical practice.

Authors:
Massimiliano Salati Giulia Orsi Elisabeth Smyth Giuseppe Aprile Giordano Beretta Fernando De Vita Maria Di Bartolomeo Valentina Fanotto Sara Lonardi Federica Morano Filippo Pietrantonio Carmine Pinto Lorenza Rimassa Enrico Vasile Caterina Vivaldi Alberto Zaniboni Pina Ziranu Stefano Cascinu

Cancer Treat Rev 2019 09 14;79:101889. Epub 2019 Aug 14.

Department of Medical Oncology, Universita' di Modena e Reggio Emilia, Modena, Italy.

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September 2019

A validated prognostic classifier for BRAF-mutated metastatic colorectal cancer: the 'BRAF BeCool' study.

Authors:
Fotios Loupakis Rossana Intini Chiara Cremolini Armando Orlandi Andrea Sartore-Bianchi Filippo Pietrantonio Nicoletta Pella Andrea Spallanzani Emanuela Dell'Aquila Mario Scartozzi Emmanuele De Luca Lorenza Rimassa Vincenzo Formica Francesco Leone Lorenzo Calvetti Giuseppe Aprile Lorenzo Antonuzzo Federica Urbano Hans Prenen Francesca Negri Samantha Di Donato Pasquale Buonandi Gianluca Tomasello Antonio Avallone Fable Zustovich Roberto Moretto Carlotta Antoniotti Lisa Salvatore Maria Alessandra Calegari Salvatore Siena Federica Morano Elena Ongaro Stefano Cascinu Daniele Santini Pina Ziranu Marta Schirripa Federica Buggin Alessandra Anna Prete Ilaria Depetris Paola Biason Sara Lonardi Vittorina Zagonel Matteo Fassan Massimo Di Maio

Eur J Cancer 2019 09 19;118:121-130. Epub 2019 Jul 19.

S.C.D.U. Medical Oncology, A.O. Ordine Mauriziano Hospital, Department of Oncology, University of Turin, Turin, Italy.

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September 2019

Maintenance Therapy With Panitumumab Alone vs Panitumumab Plus Fluorouracil-Leucovorin in Patients With RAS Wild-Type Metastatic Colorectal Cancer: A Phase 2 Randomized Clinical Trial.

Authors:
Filippo Pietrantonio Federica Morano Salvatore Corallo Rosalba Miceli Sara Lonardi Alessandra Raimondi Chiara Cremolini Lorenza Rimassa Francesca Bergamo Andrea Sartore-Bianchi Marco Tampellini Patrizia Racca Matteo Clavarezza Rosa Berenato Marta Caporale Maria Antista Monica Niger Valeria Smiroldo Roberto Murialdo Alberto Zaniboni Vincenzo Adamo Gianluca Tomasello Monica Giordano Fausto Petrelli Raffaella Longarini Saverio Cinieri Alfredo Falcone Vittorina Zagonel Maria Di Bartolomeo Filippo de Braud

JAMA Oncol 2019 Jul 3. Epub 2019 Jul 3.

Oncology and Hemato-oncology Department, University of Milan, Milan, Italy.

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July 2019

Prognostic Impact of Microsatellite Instability in Asian Gastric Cancer Patients Enrolled in the ARTIST Trial.

Authors:
Rosalba Miceli Jiyeong An Maria Di Bartolomeo Federica Morano Seung Tae Kim Se Hoon Park Min Gew Choi Joon Ho Lee Alessandra Raimondi Giovanni Fucà Tae Sung Sohn Jae Moon Bae Sung Kim Do Hoon Lim Won Ki Kang Kyoung-Mee Kim Filippo Pietrantonio Jeeyun Lee

Oncology 2019 2;97(1):38-43. Epub 2019 May 2.

Department of Medical Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

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July 2019

Metronomic Capecitabine With Cyclophosphamide Regimen in Unresectable or Relapsed Pseudomyxoma Peritonei.

Authors:
Alessandra Raimondi Salvatore Corallo Monica Niger Maria Antista Giovanni Randon Federica Morano Massimo Milione Shigeki Kusamura Dario Baratti Marcello Guaglio Chiara Cremolini Federica Marmorino Maria Di Bartolomeo Marcello Deraco Filippo De Braud Filippo Pietrantonio

Clin Colorectal Cancer 2019 06 1;18(2):e179-e190. Epub 2019 Apr 1.

Medical Oncology Department, Istituto Nazionale dei Tumori di Milano, Fondazione IRCCS, Milan, Italy; Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy. Electronic address:

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June 2019

Benefit from anti-EGFRs in and wild-type metastatic transverse colon cancer: a clinical and molecular proof of concept study.

Authors:
Chiara Cremolini Matteo Benelli Elisa Fontana Filippo Pagani Daniele Rossini Giovanni Fucà Adele Busico Elena Conca Samantha Di Donato Fotios Loupakis Marta Schirripa Sara Lonardi Beatrice Borelli Elena Ongaro Katherine Eason Federica Morano Mariaelena Casagrande Matteo Fassan Anguraj Sadanandam Filippo de Braud Alfredo Falcone Filippo Pietrantonio

ESMO Open 2019 8;4(2):e000489. Epub 2019 Mar 8.

Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.

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March 2019

Lack of Benefit From Anti-EGFR Treatment in RAS and BRAF Wild-type Metastatic Colorectal Cancer With Mucinous Histology or Mucinous Component.

Authors:
Roberto Moretto Federica Morano Elena Ongaro Daniele Rossini Filippo Pietrantonio Mariaelena Casagrande Carlotta Antoniotti Salvatore Corallo Federica Marmorino Francesco Cortiula Federico Nichetti Beatrice Borelli Gemma Zucchelli Alessandra Boccaccino Gianluca Masi Filippo de Braud Alfredo Falcone Chiara Cremolini

Clin Colorectal Cancer 2019 06 7;18(2):116-124. Epub 2019 Mar 7.

Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy; Department of Translational Research and New Technology in Medicine and Surgery, University of Pisa, Pisa, Italy. Electronic address:

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June 2019

Assessment of Ramucirumab plus paclitaxel as switch maintenance versus continuation of first-line chemotherapy in patients with advanced HER-2 negative gastric or gastroesophageal junction cancers: the ARMANI phase III trial.

Authors:
Maria Di Bartolomeo Monica Niger Federica Morano Salvatore Corallo Maria Antista Stefano Tamberi Sara Lonardi Samantha Di Donato Rossana Berardi Mario Scartozzi Giovanni Gerardo Cardellino Francesco Di Costanzo Lorenza Rimassa Alberto Gianluigi Luporini Raffaella Longarini Alberto Zaniboni Alessandro Bertolini Gianluca Tomasello Graziella Pinotti Giorgio Scagliotti Giampaolo Tortora Andrea Bonetti Andrea Spallanzani Giovanni Luca Frassineti Davide Tassinari Francesco Giuliani Saverio Cinieri Evaristo Maiello Claudio Verusio Sergio Bracarda Vincenzo Catalano Michele Basso Libero Ciuffreda Ferdinando De Vita Hector Soto Parra Lorenzo Fornaro Marta Caporale Filippo de Braud Filippo Pietrantonio

BMC Cancer 2019 Mar 29;19(1):283. Epub 2019 Mar 29.

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale Tumori, via G. Venezian, 1, 20133, Milan, Italy.

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March 2019

Prognostic impact of ATM mutations in patients with metastatic colorectal cancer.

Authors:
Giovanni Randon Giovanni Fucà Daniele Rossini Alessandra Raimondi Filippo Pagani Federica Perrone Elena Tamborini Adele Busico Giorgia Peverelli Federica Morano Monica Niger Maria Antista Salvatore Corallo Serena Saggio Beatrice Borelli Gemma Zucchelli Massimo Milione Giancarlo Pruneri Maria Di Bartolomeo Alfredo Falcone Filippo de Braud Chiara Cremolini Filippo Pietrantonio

Sci Rep 2019 02 27;9(1):2858. Epub 2019 Feb 27.

Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Via G. Venezian, 1 - 20133, Milan, Italy.

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February 2019

Refining the selection of patients with metastatic colorectal cancer for treatment with temozolomide using proteomic analysis of O6-methylguanine-DNA-methyltransferase.

Authors:
Sarit Schwartz Chris Szeto Yuan Tian Fabiola Cecchi Salvatore Corallo Maria Alessandra Calegari Maria Di Bartolomeo Federica Morano Alessandra Raimondi Giovanni Fucà Antonia Martinetti Ivana De Pascalis Maurizio Martini Antonino Belfiore Massimo Milione Armando Orlandi Ludovic Barault Carlo Barone Filippo de Braud Federica Di Nicolantonio Steve Benz Todd Hembrough Filippo Pietrantonio

Eur J Cancer 2019 01 19;107:164-174. Epub 2018 Dec 19.

Medical Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy; Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy. Electronic address:

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January 2019

Perioperative Bevacizumab-based Triplet Chemotherapy in Patients With Potentially Resectable Colorectal Cancer Liver Metastases.

Authors:
Filippo Pietrantonio Christian Cotsoglou Giovanni Fucà Salvatore Lo Vullo Federico Nichetti Massimo Milione Jorgelina Coppa Marta Vaiani Alessandra Alessi Michele Prisciandaro Michele Droz-Dit Busset Federica Morano Salvatore Corallo Silvia Lazzati Maria Antista Alessia Mennitto Giovanni Randon Alessandra Raimondi Antonino Belfiore Barbara Padovano Federica Perrone Luigi Mariani Maria Di Bartolomeo Filippo de Braud Vincenzo Mazzaferro

Clin Colorectal Cancer 2019 03 24;18(1):34-43.e6. Epub 2018 Nov 24.

Oncology and Hemato-Oncology Department, University of Milan, Milan, Italy; General Surgery and Liver Transplantation, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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March 2019

Duration of first-line treatment for metastatic colorectal cancer: Translating the available evidence into general recommendations for routine practice.

Authors:
Federica Morano Francesco Sclafani

Crit Rev Oncol Hematol 2018 Nov 27;131:53-65. Epub 2018 Aug 27.

The Royal Marsden NHS Foundation Trust, London and Surrey, United Kingdom. Electronic address:

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November 2018

Estimating Survival Probabilities of Advanced Gastric Cancer Patients in the Second-Line Setting: The Gastric Life Nomogram.

Authors:
Filippo Pietrantonio Francesco Barretta Valentina Fanotto Se Hoon Park Federica Morano Giovanni Fucà Monica Niger Michele Prisciandaro Nicola Silvestris Francesca Bergamo Lorenzo Fornaro Roberto Bordonaro Lorenza Rimassa Daniele Santini Gianluca Tomasello Lorenzo Antonuzzo Silvia Noventa Antonio Avallone Francesco Leone Luca Faloppi Samantha Di Donato Filippo de Braud Jeeyun Lee Ferdinando De Vita Maria Di Bartolomeo Rosalba Miceli Giuseppe Aprile

Oncology 2018 21;95(6):344-352. Epub 2018 Aug 21.

Department of Oncology, San Bortolo General Hospital, Vicenza, Italy.

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December 2018

Rapid access clinic for unexplained lymphadenopathy and suspected malignancy: prospective analysis of 1000 patients.

Authors:
Andrea Kühnl David Cunningham Margaret Hutka Clare Peckitt Hamoun Rozati Federica Morano Irene Chong Angela Gillbanks Andrew Wotherspoon Michelle Harris Tracey Murray Ian Chau

BMC Hematol 2018 14;18:19. Epub 2018 Aug 14.

1Department of Medicine, Royal Marsden NHS Foundation Trust, Downs Road, Sutton, Surrey SM2 5PT UK.

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August 2018

Ramucirumab as Second-Line Therapy in Metastatic Gastric Cancer: Real-World Data from the RAMoss Study.

Authors:
Maria Di Bartolomeo Monica Niger Giuseppe Tirino Angelica Petrillo Rosa Berenato Maria Maddalena Laterza Filippo Pietrantonio Federica Morano Maria Antista Sara Lonardi Lorenzo Fornaro Stefano Tamberi Elisa Giommoni Alberto Zaniboni Lorenza Rimassa Gianluca Tomasello Teodoro Sava Massimiliano Spada Tiziana Latiano Alessandro Bittoni Alessandro Bertolini Ilaria Proserpio Katia Bruna Bencardino Francesco Graziano Giordano Beretta Salvatore Galdy Jole Ventriglia Simone Scagnoli Andrea Spallanzani Raffaella Longarini Ferdinando De Vita

Target Oncol 2018 04;13(2):227-234

University of Campania "Luigi Vanvitelli" - School of Medicine, Naples, Italy.

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April 2018

Differential histopathologic parameters in colorectal cancer liver metastases resected after triplets plus bevacizumab or cetuximab: a pooled analysis of five prospective trials.

Authors:
Chiara Cremolini Massimo Milione Federica Marmorino Federica Morano Gemma Zucchelli Alessia Mennitto Michele Prisciandaro Sara Lonardi Alessio Pellegrinelli Daniele Rossini Francesca Bergamo Giuseppe Aprile Lucio Urbani Luca Morelli Marta Schirripa Giovanni Gerardo Cardellino Matteo Fassan Gabriella Fontanini Filippo de Braud Vincenzo Mazzaferro Alfredo Falcone Filippo Pietrantonio

Br J Cancer 2018 04 13;118(7):955-965. Epub 2018 Mar 13.

Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori - Via Venezian, 1, 20100, Milano, Italy.

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April 2018

The PANDA study: a randomized phase II study of first-line FOLFOX plus panitumumab versus 5FU plus panitumumab in RAS and BRAF wild-type elderly metastatic colorectal cancer patients.

Authors:
Francesca Battaglin Marta Schirripa Federica Buggin Filippo Pietrantonio Federica Morano Giorgia Boscolo Giuseppe Tonini Eufemia Stefania Lutrino Jessica Lucchetti Lisa Salvatore Alessandro Passardi Chiara Cremolini Ermenegildo Arnoldi Mario Scartozzi Nicoletta Pella Luca Boni Francesca Bergamo Vittorina Zagonel Fotios Loupakis Sara Lonardi

BMC Cancer 2018 01 25;18(1):98. Epub 2018 Jan 25.

Istituto Oncologico Veneto - IRCCS, S.C. Oncologia Medica 1, Dipartimento di Oncologia Clinica e Sperimentale, Via Gattamelata, 64, 35128, Padova, Italy.

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January 2018

ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer.

Authors:
Filippo Pietrantonio Federica Di Nicolantonio Alexa B Schrock Jeeyun Lee Sabine Tejpar Andrea Sartore-Bianchi Jaclyn F Hechtman Jason Christiansen Luca Novara Niall Tebbutt Giovanni Fucà Carlotta Antoniotti Seung Tae Kim Danielle Murphy Rosa Berenato Federica Morano James Sun Bosun Min Philip J Stephens Marissa Chen Luca Lazzari Vincent A Miller Robert Shoemaker Alessio Amatu Massimo Milione Jeffrey S Ross Salvatore Siena Alberto Bardelli Siraj M Ali Alfredo Falcone Filippo de Braud Chiara Cremolini

J Natl Cancer Inst 2017 12;109(12)

Azienda Ospedaliero, Universitaria Pisana, Pisa, Italy.

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December 2017

Vinorelbine in BRAF V600E mutated metastatic colorectal cancer: a prospective multicentre phase II clinical study.

Authors:
Chiara Cremolini Filippo Pietrantonio Gianluca Tomasello Vincenzo Dadduzio Roberto Moretto Federica Morano Marta Schirripa Carlotta Antoniotti Giovanni Fucà Francesca Bergamo Daniele Rossini Federico Nichetti Stamatia Ziampiri Michele Ghidini Federica Marmorino Michele Prisciandaro Alfredo Falcone Filippo De Braud Fotios Loupakis Sara Lonardi

ESMO Open 2017 10;2(3):e000241. Epub 2017 Aug 10.

Unit of Medical Oncology 1, Department of Clinical and Experimental Oncology, Istituto Oncologico Veneto IRCCS, Padua, Italy.

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August 2017

Biomarkers of Primary Resistance to Trastuzumab in HER2-Positive Metastatic Gastric Cancer Patients: the AMNESIA Case-Control Study.

Authors:
Filippo Pietrantonio Giovanni Fucà Federica Morano Annunziata Gloghini Simona Corso Giuseppe Aprile Federica Perrone Ferdinando De Vita Elena Tamborini Gianluca Tomasello Ambra Vittoria Gualeni Elena Ongaro Adele Busico Elisa Giommoni Chiara Costanza Volpi Maria Maddalena Laterza Salvatore Corallo Michele Prisciandaro Maria Antista Alessandro Pellegrinelli Lorenzo Castagnoli Serenella M Pupa Giancarlo Pruneri Filippo de Braud Silvia Giordano Chiara Cremolini Maria Di Bartolomeo

Clin Cancer Res 2018 03 5;24(5):1082-1089. Epub 2017 Dec 5.

Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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March 2018

Bilateral parotid gland metastases from gastric signet-ring cell carcinoma.

Authors:
Federico Nichetti Federica Morano Alessandra Fabbri Filippo de Braud Maria Di Bartolomeo

Tumori 2018 Dec 8;104(6):NP10-NP13. Epub 2018 May 8.

1 Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy.

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December 2018

Inactivation of DNA repair triggers neoantigen generation and impairs tumour growth.

Authors:
Giovanni Germano Simona Lamba Giuseppe Rospo Ludovic Barault Alessandro Magrì Federica Maione Mariangela Russo Giovanni Crisafulli Alice Bartolini Giulia Lerda Giulia Siravegna Benedetta Mussolin Roberta Frapolli Monica Montone Federica Morano Filippo de Braud Nabil Amirouchene-Angelozzi Silvia Marsoni Maurizio D'Incalci Armando Orlandi Enrico Giraudo Andrea Sartore-Bianchi Salvatore Siena Filippo Pietrantonio Federica Di Nicolantonio Alberto Bardelli

Nature 2017 12 29;552(7683):116-120. Epub 2017 Nov 29.

Candiolo Cancer Institute - FPO, IRCCS, Candiolo 10060, Turin, Italy.

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December 2017

Preoperative Capecitabine, Oxaliplatin, and Irinotecan in Resectable Gastric or Gastroesophageal Junction Cancer: Pathological Response as Primary Endpoint and FDG-PET Predictions.

Authors:
Rosa Berenato Federica Morano Filippo Pietrantonio Christian Cotsoglou Marta Caporale Gabriele Infante Alessandro Pellegrinelli Alessandra Alessi Carlo Battiston Jorgelina Coppa Barbara Padovano Alessia Mennitto Monica Niger Giovanni Fucà Silvia Lazzati Giorgio Greco Gabriele Delconte Filippo de Braud Vincenzo Mazzaferro Maria Di Bartolomeo

Oncology 2017 8;93(5):279-286. Epub 2017 Sep 8.

Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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March 2018

Implementation of Extensive Cytoreduction Resulted in Improved Survival Outcomes for Patients with Newly Diagnosed Advanced-Stage Ovarian, Tubal, and Peritoneal Cancers.

Authors:
Francesco Raspagliesi Giorgio Bogani Antonino Ditto Fabio Martinelli Valentina Chiappa Chiara Borghi Cono Scaffa Federica Morano Giuseppa Maltese Domenica Lorusso

Ann Surg Oncol 2017 Oct 9;24(11):3396-3405. Epub 2017 Aug 9.

Gynecologic Oncology, IRCCS National Cancer Institute, Milan, Italy.

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October 2017

Emergence of MET hyper-amplification at progression to MET and BRAF inhibition in colorectal cancer.

Authors:
Daniele Oddo Giulia Siravegna Annunziata Gloghini Claudio Vernieri Benedetta Mussolin Federica Morano Giovanni Crisafulli Rosa Berenato Giorgio Corti Chiara Costanza Volpi Michela Buscarino Monica Niger Philip D Dunne Giuseppe Rospo Emanuele Valtorta Alice Bartolini Giovanni Fucà Simona Lamba Antonia Martinetti Maria Di Bartolomeo Filippo de Braud Alberto Bardelli Filippo Pietrantonio Federica Di Nicolantonio

Br J Cancer 2017 Jul 27;117(3):347-352. Epub 2017 Jun 27.

Department of Oncology, University of Torino, Candiolo (TO) 10060, Italy.

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July 2017

Systemic Chemotherapy as Salvage Treatment for Locally Advanced Rectal Cancer Patients Who Fail to Respond to Standard Neoadjuvant Chemoradiotherapy.

Authors:
Francesco Sclafani Gina Brown David Cunningham Sheela Rao Paris Tekkis Diana Tait Federica Morano Chiara Baratelli Eleftheria Kalaitzaki Shahnawaz Rasheed David Watkins Naureen Starling Andrew Wotherspoon Ian Chau

Oncologist 2017 06 5;22(6):728-736. Epub 2017 May 5.

Department of Medicine, The Royal Marsden NHS Foundation Trust, London and Surrey, United Kingdom.

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June 2017

Platinum-Fluoropyrimidine and Paclitaxel-Based Chemotherapy in the Treatment of Advanced Anal Cancer Patients.

Authors:
Francesco Sclafani Federica Morano David Cunningham Chiara Baratelli Eleftheria Kalaitzaki David Watkins Naureen Starling Ian Chau Sheela Rao

Oncologist 2017 04 16;22(4):402-408. Epub 2017 Feb 16.

Department of Medicine, The Royal Marsden NHS Foundation Trust, London and Surrey, United Kingdom

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April 2017

Perioperative Triplet Chemotherapy and Cetuximab in Patients With RAS Wild Type High Recurrence Risk or Borderline Resectable Colorectal Cancer Liver Metastases.

Authors:
Filippo Pietrantonio Maria Di Bartolomeo Christian Cotsoglou Alessia Mennitto Rosa Berenato Federica Morano Jorgelina Coppa Federica Perrone Roberto Iacovelli Massimo Milione Alessandra Alessi Marta Vaiani Ilaria Bossi Francesca Ricchini Mauro Scotti Marta Caporale Emilio Bajetta Filippo de Braud Vincenzo Mazzaferro

Clin Colorectal Cancer 2017 09 6;16(3):e191-e198. Epub 2016 Oct 6.

Gastrointestinal and Hepatobilio-Pancreatic Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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September 2017

Heterogeneity of Acquired Resistance to Anti-EGFR Monoclonal Antibodies in Patients with Metastatic Colorectal Cancer.

Authors:
Filippo Pietrantonio Claudio Vernieri Giulia Siravegna Alessia Mennitto Rosa Berenato Federica Perrone Annunziata Gloghini Elena Tamborini Sara Lonardi Federica Morano Benedetta Picciani Adele Busico Chiara Costanza Volpi Antonia Martinetti Francesca Battaglin Ilaria Bossi Alessio Pellegrinelli Massimo Milione Chiara Cremolini Maria Di Bartolomeo Alberto Bardelli Filippo de Braud

Clin Cancer Res 2017 May 25;23(10):2414-2422. Epub 2016 Oct 25.

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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May 2017

Treatment of Metastatic Colorectal Cancer Patients ≥75 Years Old in Clinical Practice: A Multicenter Analysis.

Authors:
Roberta Grande Clara Natoli Fabrizio Ciancola Donatello Gemma Arianna Pellegrino Ida Pavese Carlo Garufi Luigi Di Lauro Domenico Corsi Diego Signorelli Isabella Sperduti Giada Cortese Emanuela Risi Federica Morano Domenico Sergi Carlo Signorelli Enzo Maria Ruggeri Germano Zampa Marco Russano Teresa Gamucci

PLoS One 2016 21;11(7):e0157751. Epub 2016 Jul 21.

Medical Oncology Unit, ASL Frosinone, Frosinone, Italy.

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July 2017

MET-Driven Resistance to Dual EGFR and BRAF Blockade May Be Overcome by Switching from EGFR to MET Inhibition in BRAF-Mutated Colorectal Cancer.

Authors:
Filippo Pietrantonio Daniele Oddo Annunziata Gloghini Emanuele Valtorta Rosa Berenato Ludovic Barault Marta Caporale Adele Busico Federica Morano Ambra Vittoria Gualeni Alessandra Alessi Giulia Siravegna Federica Perrone Maria Di Bartolomeo Alberto Bardelli Filippo de Braud Federica Di Nicolantonio

Cancer Discov 2016 09 20;6(9):963-71. Epub 2016 Jun 20.

Department of Oncology, University of Torino, Candiolo (TO), Italy. Candiolo Cancer Institute-FPO, IRCCS, Candiolo (TO), Italy.

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September 2016

Incidence and risk of pulmonary toxicity in patients treated with mTOR inhibitors for malignancy. A meta-analysis of published trials.

Authors:
Roberto Iacovelli Antonella Palazzo Silvia Mezi Federica Morano Giuseppe Naso Enrico Cortesi

Acta Oncol 2012 Sep 22;51(7):873-9. Epub 2012 Aug 22.

Dipartimento di Scienze Radiologiche, Oncologiche e Anatomo-Patologiche, Sapienza Università di Roma, Rome, Italy.

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September 2012

Incidence of thromboembolic events in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiotherapy.

Authors:
Silvia Mezi Daniela Musio Errico Orsi Francesca de Felice Isabella Verdinelli Federica Morano Nicola Raffetto Vincenzo Tombolini

Acta Oncol 2013 Jan 7;52(1):187-90. Epub 2012 Jun 7.

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January 2013