Federica Gemignani

Federica Gemignani

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Federica Gemignani

Federica Gemignani

Publications by authors named "Federica Gemignani"

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85Publications

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Bonafide Targets of Deregulated microRNAs in Non-Small Cell Lung Cancer as Tool to Identify Novel Therapeutic Targets: A Review.

Curr Pharm Des 2017 ;23(1):55-72

Department of Biology, University of Pisa, P.O. Box: via Derna1, Pisa, Italy.

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January 2018

The genetic susceptibility in the development of malignant pleural mesothelioma.

J Thorac Dis 2018 Jan;10(Suppl 2):S246-S252

Department of Biology, University of Pisa, Pisa, Italy.

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January 2018

Overexpressed genes in malignant pleural mesothelioma: implications in clinical management.

J Thorac Dis 2018 Jan;10(Suppl 2):S369-S382

Department of Biology, Genetic Unit, University of Pisa, Pisa, Italy.

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January 2018

Identification of MiR-21-5p as a Functional Regulator of Mesothelin Expression Using MicroRNA Capture Affinity Coupled with Next Generation Sequencing.

PLoS One 2017 26;12(1):e0170999. Epub 2017 Jan 26.

Respiratory Research Division, Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Republic of Ireland.

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August 2017

Inherited variants in genes somatically mutated in thyroid cancer.

PLoS One 2017 14;12(4):e0174995. Epub 2017 Apr 14.

Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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April 2017

Environmental risk factors for pancreatic cancer: an update.

Arch Toxicol 2016 Nov 18;90(11):2617-2642. Epub 2016 Aug 18.

Genetic Unit, Department of Biology, University of Pisa, Via Derna, 1, 56121, Pisa, Italy.

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November 2016

Targeting hypoxic response for cancer therapy.

Oncotarget 2016 Mar;7(12):13464-78

Genetics-Department of Biology, University of Pisa, Pisa, Italy.

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March 2016

Runs of homozygosity and inbreeding in thyroid cancer.

BMC Cancer 2016 Mar 16;16:227. Epub 2016 Mar 16.

Molecular Genetic Epidemiology, C050, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.

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March 2016

Type 2 diabetes-related variants influence the risk of developing multiple myeloma: results from the IMMEnSE consortium.

Endocr Relat Cancer 2015 Aug 22;22(4):545-59. Epub 2015 Jun 22.

Genomic Oncology AreaGENYO, Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, PTS, Granada, 18016 Granada, SpainHematology DepartmentVirgen de las Nieves University Hospital, Granada, SpainGenomic Epidemiology GroupGerman Cancer Research Center (DKFZ), Heidelberg, GermanyDepartment of BiologyUniversity of Pisa, Pisa, ItalyDepartment of HematologyHospital Universitario Doce de Octubre, Madrid, SpainArea of Genomic MedicineGENYO, Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, Granada, SpainSemmelweis UniversityBudapest, HungaryHaematology DepartmentUniversity Hospital of Salamanca and IBSAL, Salamanca, SpainMedical University of LodzLodz, PolandINSERM UMR 1052/CNRS 5286Université Claude Bernard Lyon I, Lyon, FranceMorales Meseguer General University HospitalMurcia, SpainHaematoloy ClinikHolly Cross Cancer Center, Kielce, PolandINSERMU900, Genetic Epidemiology of Cancers team, Institut Curie, Mines ParisTech, Paris, FranceLife and Health Sciences Research Institute (ICVS)School of Health Sciences, University of Minho, Braga, PortugalICVS/3B's - PT Government Associate LaboratoryBraga/Guimarães, PortugalMolecular Oncology Research CenterBarretos Cancer Hospital, Barretos, BrazilIDIBELL - Catalan Institute of OncologyUniversity of Barcelona, Barcelona 08907, SpainDepartment of HematologyCracow University Hospital, Cracow, PolandOrgan CenterHospital of Southern Jutland, DK-6200 Aabenraa, DenmarkFaculty of Health SciencesInstitute of Regional Health Research, University of Southern Denmark, DK-5000 Odense C, DenmarkUO HematologyDepartment of Internal and Experimental Medicine, University of Pisa, Pisa, ItalyClinic of Biochemistry and ImmunologyLaboratory Center, Hospital of Southern Jutland, Aabenraa, DenmarkDepartment of HaematologyRigshospitalet and Roskilde Hospital, Copenhagen University, Copenhagen, Denmark Genomic Oncology AreaGENYO, Cen

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August 2015

Novel genetic variants in differentiated thyroid cancer and assessment of the cumulative risk.

Sci Rep 2015 Mar 10;5:8922. Epub 2015 Mar 10.

1] Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany [2] Center for Primary Health Care Research, Clinical Research Center, Lund University, Malmö, Sweden.

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March 2015

A common polymorphism within MSLN affects miR-611 binding site and soluble mesothelin levels in healthy people.

J Thorac Oncol 2014 Nov;9(11):1662-8

*Laboratory of Computational Oncology, Centre for Integrative Biology, CIBIO, University of Trento, Trento, Italy; †Department of Biology, University of Pisa, Pisa, Italy; ‡Division of Thoracic Surgery, Cardiac and Thoracic Department, University of Pisa, Pisa, Italy; §Department of Medicine, Vercelli Teaching Hospital, Vercelli, Italy; and ‖Section of Occupational Medicine, School of Medicine and Surgery, University of Pisa, Pisa, Italy.

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November 2014

Novel genome-wide association study-based candidate loci for differentiated thyroid cancer risk.

J Clin Endocrinol Metab 2014 Oct 16;99(10):E2084-92. Epub 2014 Jul 16.

Department of Biology (G.F., M.C., E.P., S.L., F.G.), University of Pisa, 56123 Pisa, Italy; Molecular Genetic Epidemiology (A.K., B.C., K.H., A.F.), German Cancer Research Center, 69120 Heidelberg, Germany; Department of Endocrinology and Metabolism (R.E., C.R., A.C.), University of Pisa, 56124 Pisa, Italy; Blood Centre (F.B.), Azienda Ospedaliero Universitaria A. Meyer, 50139 Firenze, Italy; Department of Genomics (P.H., S.H.), Life and Brain Center and Institute of Human Genetics (P.H., S.H.), University of Bonn, D-53127 Bonn, Germany; Division of Medical Genetics (P.H., S.H.), University Hospital Basel and Department of Biomedicine, University of Basel, CH-4058 Basel, Switzerland; Department of Nuclear Medicine and Endocrine Oncology (M.K., D.K., B.J.), Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, 44-101 Gliwice, Poland; Grup de Mutagènesi (S.P., R.M., A.V.), Departament de Genètica i de Microbiologia, Facultat de Biociències, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallés, Barcelona, Spain; Centro de Investigación Biomédica en Red y Epidemiologia y Salud Pública (S.P., R.M., A.V.), Instituto de Salud Carlos III, 28029 Madrid, Spain; and Center for Primary Health Care Research (K.H., A.F.), Clinical Research Center, Lund University, 205 02 Malmö, Sweden.

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October 2014

MicroRNA binding site polymorphisms as biomarkers in cancer management and research.

Pharmgenomics Pers Med 2014 23;7:173-91. Epub 2014 Jul 23.

Department of Biology, University of Pisa, Pisa, Italy.

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August 2014

Genetic variants and multiple myeloma risk: IMMEnSE validation of the best reported associations--an extensive replication of the associations from the candidate gene era.

Cancer Epidemiol Biomarkers Prev 2014 Apr 12;23(4):670-4. Epub 2014 Feb 12.

Authors' Affiliations: Genomic Epidemiology Group, Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Hematology, Cracow University Hospital, Cracow; Medical University of Łodz; Laboratory of Clinical and Transplant Immunology and Genetics, Copernicus Memorial Hospital, Łodz; Rzeszow Regional Hospital, Rzeszow; Holycross Cancer Center, Kielce, Poland; Department of Hematology, Hospital Universitario Doce de Octubre, Madrid; Morales Meseguer General University Hospital, Murcia; University Hospital of Salamanca, Salamanca; Genomic Oncology Area, GENYO, Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government; Hematology Department, Virgen de las Nieves University Hospital, Granada; IDIBELL-Catalan Institute of Oncology, University of Barcelona, Barcelona, Spain; Semmelweis University, Budapest, Hungary; Institut National de la Santé et de la Recherche Medicale (INSERM) UMR 1052/CNRS 5286, Université Claude Bernard Lyon I, Lyon; Genetic Epidemiology of Cancer team, INSERM, U900, Institut Curie, Mines ParisTech, Paris, France; Department of Biology, University of Pisa, Pisa, Italy; Clinic of Immunology, Laboratory Center, Hospital of Southern Jutland, Sønderborg; Organ Center, Hospital of Southern Jutland, Aabenraa; Institute of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Odense C; National Research Centre for the Working Environment, Copenhagen; Roskilde Hospital, Copenhagen University, Roskilde, Denmark; Life and Health Sciences Research Institute, University of Minho, Braga; ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal; UO Hematology, Department of Internal and Experimental Medicine, University of Pisa, Pisa, Italy; and Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, Brazil.

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April 2014

Risk of differentiated thyroid carcinoma and polymorphisms within the susceptibility cancer region 8q24.

Cancer Epidemiol Biomarkers Prev 2013 Nov 5;22(11):2121-5. Epub 2013 Sep 5.

Authors' Affiliations: Department of Biology, University of Pisa, Pisa; Center for Integrated Biology, University of Trento, Trento; Department of Endocrinology and Metabolism, Orthopaedics and Traumatology, Occupational Medicine, University of Pisa, Pisa; and Operative Unit of Laboratory of Clinical Chemistry Analyses, University Hospital of Cisanello, Pisa, Italy.

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November 2013

Variation within 3'-UTRs of base excision repair genes and response to therapy in colorectal cancer patients: A potential modulation of microRNAs binding.

Clin Cancer Res 2013 Nov 13;19(21):6044-56. Epub 2013 Sep 13.

Authors' Affiliations: Human Genetics Foundation Torino; Department of Medical Sciences, University of Turin, Turin; Department of Biology, University of Pisa, Pisa; Laboratory of Computational Oncology, Center for Integrated Biology (CIBIO), University of Trento, Trento, Italy; Department of Molecular Biology of Cancer, Institute of Experimental Medicine; Departments of Surgery and Oncology, Thomayer Hospital; Institute of Biology and Department of Medical Genetics; and Department of Oncology, First Faculty of Medicine, Charles University, Prague, Czech Republic.

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November 2013

Role of variations within microRNA-binding sites in cancer.

Mutagenesis 2012 Mar;27(2):205-10

Department of Biology, University of Pisa, Via Derna 1, 56100 Pisa, Italy.

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March 2012

Two novel polymorphisms in 5' flanking region of the mesothelin gene are associated with soluble mesothelin-related peptide (SMRP) levels.

Int J Biol Markers 2011 Apr-Jun;26(2):117-23

Department of Endocrinology and Metabolism, Orthopedics and Traumatology, Occupational Medicine, University of Pisa - Italy.

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October 2011

Prediction of the biological effect of polymorphisms within microRNA binding sites.

Methods Mol Biol 2011 ;676:197-210

Genetics, Department of Biology, University of Pisa, Pisa, Italy.

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January 2011

COMPASSS (COMplex PAttern of Sequence Search Software), a simple and effective tool for mining complex motifs in whole genomes.

Bioinformatics 2010 Jul 25;26(14):1777-8. Epub 2010 May 25.

Laboratory of Microbiology and Genetics - Ospedale di Circolo e Fondazione Macchi, University of Insubria, Viale Borri 57 21100 Varese, Italy.

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July 2010

Polymorphisms in the putative micro-RNA-binding sites of mesothelin gene are associated with serum levels of mesothelin-related protein.

Occup Environ Med 2010 Apr 26;67(4):233-6. Epub 2009 Oct 26.

Department of Endocrinology and Metabolism, Orthopaedics and Traumatology, Occupational Medicine, University of Pisa, via Paradisa, 2 Pisa 56124, Italy.

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April 2010

Genetic susceptibility to malignant pleural mesothelioma and other asbestos-associated diseases.

Mutat Res 2008 Jul-Aug;659(1-2):126-36. Epub 2008 Feb 23.

Unit of Molecular Epidemiology, National Cancer Research Institute, Genoa, Italy.

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September 2008

Polymorphisms within micro-RNA-binding sites and risk of sporadic colorectal cancer.

Carcinogenesis 2008 Mar 12;29(3):579-84. Epub 2008 Jan 12.

Dipartimento di Biologia, University of Pisa, Via Derna, 1, 56126 Pisa, Italy.

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March 2008

A catalog of polymorphisms falling in microRNA-binding regions of cancer genes.

DNA Cell Biol 2008 Jan;27(1):35-43

Department of Biology, University of Pisa, Pisa, Italy.

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January 2008

Interleukin-4 and interleukin-4 receptor polymorphisms and colorectal cancer risk.

Eur J Cancer 2007 Mar 26;43(4):762-8. Epub 2007 Jan 26.

Genetics - Department of Biology, University of Pisa, via S. Giuseppe 22, 56126, Pisa, Italy.

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March 2007

Polymorphisms within inflammatory genes and colorectal cancer.

J Negat Results Biomed 2006 Oct 24;5:15. Epub 2006 Oct 24.

Genetics-Department of Biology, University of Pisa, via S, Giuseppe 22, 56126, Pisa, Italy.

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October 2006

Single tube genotyping of GSTM1, GSTT1 and TP53 polymorphisms by multiplex PCR.

DNA Seq 2006 Oct;17(5):396-9

University of Pisa, Dipartimento di Biologia, Genetica, via S. Giuseppe 22, 56126, Pisa, Italy.

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October 2006

Polymorphisms in genes of nucleotide and base excision repair: risk and prognosis of colorectal cancer.

Clin Cancer Res 2006 Apr;12(7 Pt 1):2101-8

Institut d'Investigació Biomèdica de Bellvitge, Institut Catala d'Oncologia, Hospitalet, Barcelona, Spain.

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April 2006

A database of single-nucleotide polymorphisms and a genotyping microarray for genetic epidemiology of lung cancer.

Exp Lung Res 2005 Mar;31(2):223-58

Dipartimento di Scienze dell'Uomo e dell' Ambiente, Genome Research Group, University of Pisa, Pisa, Italy.

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March 2005

Generation of a DNA microarray for determination of E6 natural variants of human papillomavirus type 16.

J Virol Methods 2004 Aug;119(2):95-102

International Agency for Research on Cancer, World Health Organization, 150 Cours Albert Thomas, 69372 Lyon Cedex 08, France.

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August 2004

Evaluation of a microarray for genotyping polymorphisms related to xenobiotic metabolism and DNA repair.

Biotechniques 2003 Oct;35(4):816-20, 822, 824-7

International Agency for Research on Cancer, Lyon, France.

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October 2003

High-level expression of hemoglobin A in human thalassemic erythroid progenitor cells following lentiviral vector delivery of an antisense snRNA.

Blood 2003 Jan 15;101(1):104-11. Epub 2002 Aug 15.

Curriculum in Genetics and Molecular Biology, University of North Carolina Gene Therapy Center, Department of Pharmacology and Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, 27599, USA.

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January 2003

Systemically delivered antisense oligomers upregulate gene expression in mouse tissues.

Nat Biotechnol 2002 Dec 11;20(12):1228-33. Epub 2002 Nov 11.

Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA.

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December 2002

Reliable detection of beta-thalassemia and G6PD mutations by a DNA microarray.

Clin Chem 2002 Nov;48(11):2051-4

IARC, International Agency for Research on Cancer, 150, Cours Albert Thomas, Lyon 69372, France.

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November 2002

Temperature-dependent splicing of beta-globin pre-mRNA.

Nucleic Acids Res 2002 Nov;30(21):4592-8

Lineberger Comprehensive Cancer Center and Department of Pharmacology, CB 7295, University of North Carolina, Chapel Hill, NC 27599-7295, USA.

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November 2002

A catalogue of polymorphisms related to xenobiotic metabolism and cancer susceptibility.

Pharmacogenetics 2002 Aug;12(6):459-63

Genome Analysis Group, International Agency for Research on Cancer, Lyon, France.

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August 2002