Federica Ganci

Two distinct TP53 mutations in HNSCC primary tumor: Only one circulates in the blood.

Authors:

Federica Ganci Matteo Allegretti Valentina Manciocco Francesco Fiorentino Giuseppe Sanguineti Patrizio Giacomini Raul Pellini Francesca Spinella Giovanni Blandino

Oral Oncol 2020 Nov 21:105096. Epub 2020 Nov 21.

Oncogenomic and Epigenetic Unit, IRCSS Regina Elena National Cancer Institute, Via Elio Chianesi, 53, Rome 00144, Italy. Electronic address:

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November 2020

LINC00174 is a novel prognostic factor in thymic epithelial tumors involved in cell migration and lipid metabolism.

Cell Death Dis 2020 11 7;11(11):959. Epub 2020 Nov 7.

Department of Anatomical, Histological, Forensic & Orthopedic Sciences, Section of Histology & Medical Embryology, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.

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November 2020

Thymic Epithelial Tumors as a Model of Networking: Development of a Synergistic Strategy for Clinical and Translational Research Purposes.

Front Oncol 2020 14;10:922. Epub 2020 Jul 14.

Department of Pathology, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

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July 2020

Non-coding RNAs as Putative Biomarkers of Cancer-Associated Cachexia.

Authors:

Sara Donzelli Alessia Farneti Laura Marucci Federica Ganci Andrea Sacconi Sabrina Strano Giuseppe Sanguineti Giovanni Blandino

Front Cell Dev Biol 2020 21;8:257. Epub 2020 Apr 21.

Oncogenomic and Epigenetic Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

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April 2020

PI3K Inhibitors Curtail MYC-Dependent Mutant p53 Gain-of-Function in Head and Neck Squamous Cell Carcinoma.

Clin Cancer Res 2020 06 22;26(12):2956-2971. Epub 2020 Jan 22.

Oncogenomic and Epigenetic Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

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June 2020

The miR-205-5p/BRCA1/RAD17 Axis Promotes Genomic Instability in Head and Neck Squamous Cell Carcinomas.

Authors:

Fabio Valenti Andrea Sacconi Federica Ganci Giuseppe Grasso Sabrina Strano Giovanni Blandino Silvia Di Agostino

Cancers (Basel) 2019 09 11;11(9). Epub 2019 Sep 11.

Oncogenomic and Epigenetic Unit, Department of Diagnostic Research and Technological Innovation, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.

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September 2019

miR-96-5p targets PTEN expression affecting radio-chemosensitivity of HNSCC cells.

Authors:

Mahrou Vahabi Claudio Pulito Andrea Sacconi Sara Donzelli Marco D'Andrea Valentina Manciocco Raul Pellini Paola Paci Giuseppe Sanguineti Lidia Strigari Giuseppe Spriano Paola Muti Pier Paolo Pandolfi Sabrina Strano Shahrokh Safarian Federica Ganci Giovanni Blandino

J Exp Clin Cancer Res 2019 Mar 29;38(1):141. Epub 2019 Mar 29.

Oncogenomics and Epigenetics Unit, IRCCS-Regina Elena National Cancer Institute, 00144, Rome, Italy.

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March 2019

Argonaute 2 drives miR-145-5p-dependent gene expression program in breast cancer cells.

Authors:

Teresa Bellissimo Claudia Tito Federica Ganci Andrea Sacconi Silvia Masciarelli Giuseppe Di Martino Natale Porta Mirko Cirenza Melissa Sorci Luciana De Angelis Paolo Rosa Antonella Calogero Alessandro Fatica Vincenzo Petrozza Giulia Fontemaggi Giovanni Blandino Francesco Fazi

Cell Death Dis 2019 01 8;10(1):17. Epub 2019 Jan 8.

Department of Anatomical, Histological, Forensic & Orthopedic Sciences, Section of Histology & Medical Embryology, Sapienza University of Rome, laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.

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January 2019

Long Non-coding MIR205HG Depletes Hsa-miR-590-3p Leading to Unrestrained Proliferation in Head and Neck Squamous Cell Carcinoma.

Authors:

Silvia Di Agostino Fabio Valenti Andrea Sacconi Giulia Fontemaggi Matteo Pallocca Claudio Pulito Federica Ganci Paola Muti Sabrina Strano Giovanni Blandino

Theranostics 2018 12;8(7):1850-1868. Epub 2018 Feb 12.

Oncogenomic and Epigenetic Unit, Department of Diagnostic Research and Technological Innovation, IRCCS Regina Elena National Cancer Institute, Rome 00144, Italy.

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February 2019

The oncogenic role of circPVT1 in head and neck squamous cell carcinoma is mediated through the mutant p53/YAP/TEAD transcription-competent complex.

Authors:

Lorena Verduci Maria Ferraiuolo Andrea Sacconi Federica Ganci Jlenia Vitale Teresa Colombo Paola Paci Sabrina Strano Giuseppe Macino Nikolaus Rajewsky Giovanni Blandino

Genome Biol 2017 Dec 20;18(1):237. Epub 2017 Dec 20.

Oncogenomic and Epigenetic Unit, Italian National Cancer Institute, "Regina Elena", 00144, Rome, Italy.

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December 2017

MiRNA-513a-5p inhibits progesterone receptor expression and constitutes a risk factor for breast cancer: the hOrmone and Diet in the ETiology of breast cancer prospective study.

Authors:

Paola Muti Sara Donzelli Andrea Sacconi Ahmed Hossain Federica Ganci Tania Frixa Sabina Sieri Vittorio Krogh Franco Berrino Francesca Biagioni Sabrina Strano Joseph Beyene Yosef Yarden Giovanni Blandino

Carcinogenesis 2018 02;39(2):98-108

Department of Oncology, Faculty of Health Science, McMaster University, Hamilton, ON, Canada.

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February 2018

Altered peritumoral microRNA expression predicts head and neck cancer patients with a high risk of recurrence.

Authors:

Federica Ganci Andrea Sacconi Valentina Manciocco Renato Covello Maria Benevolo Francesca Rollo Sabrina Strano Sara Valsoni Silvio Bicciato Giuseppe Spriano Paola Muti Giulia Fontemaggi Giovanni Blandino

Mod Pathol 2017 10 21;30(10):1387-1401. Epub 2017 Jul 21.

Oncogenomic and Epigenetic Unit, Italian National Cancer Institute 'Regina Elena', Rome, Italy.

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October 2017

The mutant p53-ID4 complex controls VEGFA isoforms by recruiting lncRNA MALAT1.

Authors:

Magdalena Pruszko Elisa Milano Mattia Forcato Sara Donzelli Federica Ganci Silvia Di Agostino Simone De Panfilis Francesco Fazi David O Bates Silvio Bicciato Maciej Zylicz Alicja Zylicz Giovanni Blandino Giulia Fontemaggi

EMBO Rep 2017 08 26;18(8):1331-1351. Epub 2017 Jun 26.

Oncogenomic and Epigenetic Unit, Italian National Cancer Institute "Regina Elena", Rome, Italy

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August 2017

Thymic Epithelial Tumors phenotype relies on miR-145-5p epigenetic regulation.

Authors:

Teresa Bellissimo Federica Ganci Enzo Gallo Andrea Sacconi Claudia Tito Luciana De Angelis Claudio Pulito Silvia Masciarelli Daniele Diso Marco Anile Vincenzo Petrozza Felice Giangaspero Edoardo Pescarmona Francesco Facciolo Federico Venuta Mirella Marino Giovanni Blandino Francesco Fazi

Mol Cancer 2017 05 10;16(1):88. Epub 2017 May 10.

Deptartment of Anatomical, Histological, Forensic & Orthopaedic Sciences, Section of Histology & Medical Embryology, Sapienza University of Rome, Rome, Italy.

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May 2017

microRNAs in Cancer Chemoprevention: Method to Isolate Them from Fresh Tissues.

Authors:

Federica Ganci Giovanni Blandino

Methods Mol Biol 2016 ;1379:21-9

Laboratory of Translational Oncogenomics, Molecular Medicine Department, Regina Elena National Cancer Institute, Rome, Italy.

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September 2016

Circulating miR-21-5p and miR-148a-3p as emerging non-invasive biomarkers in thymic epithelial tumors.

Authors:

Teresa Bellissimo Emanuele Russo Federica Ganci Carmen Vico Andrea Sacconi Flavia Longo Domenico Vitolo Marco Anile Daniele Disio Mirella Marino Giovanni Blandino Federico Venuta Francesco Fazi

Cancer Biol Ther 2016 ;17(1):79-82

a Department of Anatomical, Histological , Forensic and orthopedic Sciences, Section of Histology & Medical Embryology, Sapienza University of Rome , Rome , Italy.

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October 2016

miR-181c associates with tumor relapse of high grade osteosarcoma.

Authors:

Federica Mori Andrea Sacconi Valeria Canu Federica Ganci Mariangela Novello Vincenzo Anelli Renato Covello Virginia Ferraresi Paola Muti Roberto Biagini Giovanni Blandino Sabrina Strano

Oncotarget 2015 Jun;6(16):13946-61

Molecular Chemoprevention Unit, Regina Elena National Cancer Institute, Rome, Italy.

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June 2015

Gain of function mutant p53 proteins cooperate with E2F4 to transcriptionally downregulate RAD17 and BRCA1 gene expression.

Authors:

Fabio Valenti Federica Ganci Giulia Fontemaggi Andrea Sacconi Sabrina Strano Giovanni Blandino Silvia Di Agostino

Oncotarget 2015 Mar;6(8):5547-66

Translational Oncogenomic Unit, Molecular Medicine Area, Regina Elena National Cancer Institute, Rome 00144, Italy.

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March 2015

MicroRNA expression as predictor of local recurrence risk in oral squamous cell carcinoma.

Authors:

Federica Ganci Andrea Sacconi Valentina Manciocco Isabella Sperduti Paolo Battaglia Renato Covello Paola Muti Sabrina Strano Giuseppe Spriano Giulia Fontemaggi Giovanni Blandino

Head Neck 2016 04 24;38 Suppl 1:E189-97. Epub 2015 Jun 24.

Translational Oncogenomics Unit, Italian National Cancer Institute "Regina Elena", Rome, Italy.

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April 2016

Downregulation of microRNAs 145-3p and 145-5p is a long-term predictor of postmenopausal breast cancer risk: The ORDET prospective study.

Authors:

Paola Muti Andrea Sacconi Ahmed Hossain Sara Donzelli Noa Bossel Ben Moshe Federica Ganci Sabina Sieri Vittorio Krogh Franco Berrino Francesca Biagioni Sabrina Strano Joseph Beyene Yosef Yarden Giovanni Blandino

Cancer Epidemiol Biomarkers Prev 2014 Nov 29;23(11):2471-81. Epub 2014 Jul 29.

Department of Oncology, Faculty of Health Science, McMaster University, Hamilton, Ontario, Canada. Translational Oncogenomics Unit, Regina Elena Italian National Cancer Institute, Rome, Italy.

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November 2014

MicroRNA expression profiling of thymic epithelial tumors.

Authors:

Federica Ganci Carmen Vico Etleva Korita Andrea Sacconi Enzo Gallo Federica Mori Annamaria Cambria Emanuele Russo Marco Anile Domenico Vitolo Edoardo Pescarmona Rosario Blandino Francesco Facciolo Federico Venuta Giovanni Blandino Mirella Marino Francesco Fazi

Lung Cancer 2014 Aug 29;85(2):197-204. Epub 2014 Apr 29.

Department of Anatomical, Histological, Forensic & Orthopaedic Sciences, Section of Histology & Medical Embryology, Sapienza University of Rome, Rome, Italy. Electronic address:

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August 2014