Faycal Guedj

Faycal Guedj

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Faycal Guedj

Faycal Guedj

Publications by authors named "Faycal Guedj"

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An Integrated Human/Murine Transcriptome and Pathway Approach To Identify Prenatal Treatments For Down Syndrome.

Sci Rep 2016 09 2;6:32353. Epub 2016 Sep 2.

Mother Infant Research Institute, Tufts Medical Center and the Floating Hospital for Children, Boston, MA, United States.

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http://dx.doi.org/10.1038/srep32353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009456PMC
September 2016

Males are from Mars, and females are from Venus: sex-specific fetal brain gene expression signatures in a mouse model of maternal diet-induced obesity.

Am J Obstet Gynecol 2016 05 3;214(5):623.e1-623.e10. Epub 2016 Mar 3.

Division of Genetics, Department of Pediatrics, Floating Hospital for Children, Boston, MA.

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http://dx.doi.org/10.1016/j.ajog.2016.02.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851594PMC
May 2016

Pharmacological correction of excitation/inhibition imbalance in Down syndrome mouse models.

Front Behav Neurosci 2015 20;9:267. Epub 2015 Oct 20.

Université Paris Diderot, Sorbonne Paris Cité, Adaptive Functional Biology, UMR Centre National de la Recherche Scientifique 8251 Paris, France ; Université Pierre-et-Marie-Curie Paris, 06 UMR S 1127, Centre National de la Recherche Scientifique UMR 7225, Institut National de la Santé et de la Recherche Médicale, U 1127, Sorbonne Universités, Institut du Cerveau et de la Moelle Epiniere Paris, France.

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http://dx.doi.org/10.3389/fnbeh.2015.00267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611057PMC
November 2015

The fetal brain transcriptome and neonatal behavioral phenotype in the Ts1Cje mouse model of Down syndrome.

Am J Med Genet A 2015 Sep 14;167A(9):1993-2008. Epub 2015 May 14.

Mother Infant Research Institute, Tufts Medical Center and the Floating Hospital for Children, Boston, Massachusetts.

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http://dx.doi.org/10.1002/ajmg.a.37156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844354PMC
September 2015

Analysis of adult cerebral cortex and hippocampus transcriptomes reveals unique molecular changes in the Ts1Cje mouse model of down syndrome.

Brain Pathol 2015 Jan 25;25(1):11-23. Epub 2014 Jul 25.

Mother Infant Research Institute, Floating Hospital for Children, Tufts Medical Center, Boston, MA, USA.

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http://dx.doi.org/10.1111/bpa.12151DOI Listing
January 2015

Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage.

Neurobiol Dis 2014 Sep 4;69:65-75. Epub 2014 May 4.

Univ Paris Diderot, Sorbonne Paris Cité, Adaptive Functional Biology, UMR CNRS 8251, 75205 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2014.04.016DOI Listing
September 2014

Prenatal treatment of Down syndrome: a reality?

Curr Opin Obstet Gynecol 2014 Apr;26(2):92-103

aMother Infant Research Institute, Tufts Medical Center and the Floating Hospital for Children, Boston, Massachusetts, USA bUniv Paris Diderot, Sorbonne Paris Cité, CNRS UMR 8251, Adaptive Functional Biology, Paris, France.

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http://dx.doi.org/10.1097/GCO.0000000000000056DOI Listing
April 2014

Prefrontal deficits in a murine model overexpressing the down syndrome candidate gene dyrk1a.

J Neurosci 2014 Jan;34(4):1138-47

Institut National de la Santé et de la Recherche Médicale U901, Marseille, 13009, France, Université Aix-Marseille UMR S901, Marseille, 13009, France, INMED, Marseille, 13009, France, and Université Paris Diderot, Sorbonne Paris Cité, Adaptive Functional Biology, EAC Centre National de la Recherche Scientifique 4413, Paris, 75205, France.

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http://dx.doi.org/10.1523/JNEUROSCI.2852-13.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953590PMC
January 2014

Noninvasive prenatal testing creates an opportunity for antenatal treatment of Down syndrome.

Prenat Diagn 2013 Jun;33(6):614-8

Mother Infant Research Institute, Tufts Medical Center and Floating Hospital for Children, Boston, MA, USA.

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http://dx.doi.org/10.1002/pd.4134DOI Listing
June 2013

Mice deficient in cystathionine beta synthase display increased Dyrk1A and SAHH activities in brain.

J Mol Neurosci 2013 May 15;50(1):1-6. Epub 2012 Jun 15.

Unit of Functional and Adaptative Biology, University of Paris Diderot, Sorbonne Paris Cité, EAC-CNRS 4413, 75013 Paris, France.

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http://dx.doi.org/10.1007/s12031-012-9835-0DOI Listing
May 2013

DYRK1A: a master regulatory protein controlling brain growth.

Neurobiol Dis 2012 Apr 26;46(1):190-203. Epub 2012 Jan 26.

Univ Paris Diderot, Sorbonne Paris Cité, Adaptive Functional Biology, EAC CNRS 4413, 75205 Paris, France.

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http://dx.doi.org/10.1016/j.nbd.2012.01.007DOI Listing
April 2012

Dysregulation of growth factor receptor-bound protein 2 and fascin in hippocampus of mice polytransgenic for chromosome 21 structures.

Hippocampus 2007 ;17(12):1180-92

Department of Pediatrics, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/hipo.20351DOI Listing
February 2008