Mr Fayaz Ali Larik, B.Sc, Msc, Mphil (completed) and PhD in progress - School of Chemistry, University of new south wales, Sydney, Australia - Mr

Mr Fayaz Ali Larik

B.Sc, Msc, Mphil (completed) and PhD in progress

School of Chemistry, University of new south wales, Sydney, Australia

Mr

Sydney, NSW | Australia

Additional Specialties: organic synthesis, peptide chemistry, photochromic molecules

ORCID logohttps://orcid.org/0000-0002-8491-5229

Mr Fayaz Ali Larik, B.Sc, Msc, Mphil (completed) and PhD in progress - School of Chemistry, University of new south wales, Sydney, Australia - Mr

Mr Fayaz Ali Larik

B.Sc, Msc, Mphil (completed) and PhD in progress

Introduction

Primary Affiliation: School of Chemistry, University of new south wales, Sydney, Australia - Sydney, NSW , Australia

Additional Specialties:

Research Interests:

Education

Jun 2018 - Jul 2018
University of New South Wales
PhD in progress
Chemistry
Feb 2015 - Mar 2017
Quaid-i-Azam University
M.Phil
Chemistry

Publications

29Publications

269Reads

2Profile Views

6PubMed Central Citations

Investigation on the effect of alkyl chain linked mono-thioureas as Jack bean urease inhibitors, SAR, pharmacokinetics ADMET parameters and molecular docking studies.

Bioorg Chem 2019 May 8;86:473-481. Epub 2019 Feb 8.

Department of Biological Sciences, College of Natural Sciences, Kongju National University, 56 Gongjudehak-Ro, Gongju, Chungnam 314-701, Republic of Korea.

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http://dx.doi.org/10.1016/j.bioorg.2019.02.011DOI Listing
May 2019
1 Read
2.152 Impact Factor

Synthesis of sulfonamide, amide and amine hybrid pharmacophore, an entry of new class of carbonic anhydrase II inhibitors and evaluation of chemo-informatics and binding analysis.

Bioorg Chem 2019 May 10;86:624-630. Epub 2019 Feb 10.

Department of Biological Sciences, College of Natural Sciences, Kongju National University, 56 Gongjudehak-Ro, Gongju, Chungnam 32588, Republic of Korea.

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http://dx.doi.org/10.1016/j.bioorg.2019.01.060DOI Listing
May 2019
2.152 Impact Factor

1-(2-Hydroxy-5-((trimethylsilyl)ethynyl)phenyl)ethanone based α,β-unsaturated derivatives an alternate to non-sulfonamide carbonic anhydrase II inhibitors, synthesis via Sonogashira coupling, binding analysis, Lipinsk's rule validation.

Bioorg Chem 2019 Mar 24;84:170-176. Epub 2018 Nov 24.

Department of Biological Sciences, College of Natural Sciences, Kongju National University, 56 Gongjudehak-Ro, Gongju, Chungnam 314-701, Republic of Korea.

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http://dx.doi.org/10.1016/j.bioorg.2018.11.031DOI Listing
March 2019
2 Reads
2.152 Impact Factor

Novel 1,3-oxazine-tetrazole hybrids as mushroom tyrosinase inhibitors and free radical scavengers: Synthesis, kinetic mechanism, and molecular docking studies.

Chem Biol Drug Des 2019 Feb 3;93(2):123-131. Epub 2018 Dec 3.

Department of Biological Sciences, College of Natural Sciences, Kongju National University, Chungnam, Korea.

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http://dx.doi.org/10.1111/cbdd.13352DOI Listing
February 2019
5 Reads
2.485 Impact Factor

Synthesis, theoretical, spectroscopic and electrochemical DNA binding investigations of 1, 3, 4-thiadiazole derivatives of ibuprofen and ciprofloxacin: Cancer cell line studies.

J Photochem Photobiol B 2018 Dec 9;189:104-118. Epub 2018 Oct 9.

Healthcare Biotechnology Atta-ur-Rehman School of Applied Biosciences National University of Science and Technology (NUST), Islamabad, Pakistan.

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https://linkinghub.elsevier.com/retrieve/pii/S10111344183068
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http://dx.doi.org/10.1016/j.jphotobiol.2018.10.006DOI Listing
December 2018
4 Reads
2.960 Impact Factor

Synthetic approaches to access acortatarins, shensongines and pollenopyrroside; potent antioxidative spiro-alkaloids with a naturally rare morpholine moiety.

Fitoterapia 2018 Sep 1;129:366-382. Epub 2018 Apr 1.

Department of Chemistry, Quaid-i-Azam University, 45320 Islamabad, Pakistan.

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http://dx.doi.org/10.1016/j.fitote.2018.03.014DOI Listing
September 2018
9 Reads
2.220 Impact Factor

New cholinesterase inhibitors for Alzheimer's disease: Structure activity relationship, kinetics and molecular docking studies of 1-butanoyl-3-arylthiourea derivatives.

Int J Biol Macromol 2018 Sep 2;116:144-150. Epub 2018 May 2.

Centre for Advanced Drug Research, COMSATS Institute of Information Technology, Abbottabad 22060, Pakistan. Electronic address:

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http://dx.doi.org/10.1016/j.ijbiomac.2018.05.001DOI Listing
September 2018
10 Reads
2.860 Impact Factor

Exploration of carboxy pyrazole derivatives: Synthesis, alkaline phosphatase, nucleotide pyrophosphatase/phosphodiesterase and nucleoside triphosphate diphosphohydrolase inhibition studies with potential anticancer profile.

Eur J Med Chem 2018 Aug 7;156:461-478. Epub 2018 Jul 7.

Centre for Advanced Drug Research, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.07.002DOI Listing
August 2018
9 Reads
3.450 Impact Factor

Synthesis and Molecular Docking Studies of (E)-4-(Substituted-benzylideneamino)-2H-Chromen-2-one Derivatives: Entry to New Carbonic Anhydrase Class Of Inhibitors.

Drug Res (Stuttg) 2018 Jul 12;68(7):378-386. Epub 2018 Feb 12.

Department of Biological Sciences, College of Natural Sciences, Kongju National University, Gongju, Chungnam, Republic of Korea.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-123998
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http://dx.doi.org/10.1055/s-0043-123998DOI Listing
July 2018
9 Reads

Synthesis of sulfadiazinyl acyl/aryl thiourea derivatives as calf intestinal alkaline phosphatase inhibitors, pharmacokinetic properties, lead optimization, Lineweaver-Burk plot evaluation and binding analysis.

Bioorg Med Chem 2018 07 2;26(12):3707-3715. Epub 2018 Jun 2.

Department of Biological Sciences, College of Natural Sciences, Kongju National University, 56 Gongjudehak-Ro, Gongju, Chungnam 314-701, Republic of Korea.

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http://dx.doi.org/10.1016/j.bmc.2018.06.002DOI Listing
July 2018
8 Reads
2.793 Impact Factor

Synthesis, enzyme inhibitory kinetics, and computational studies of novel 1-(2-(4-isobutylphenyl) propanoyl)-3-arylthioureas as Jack bean urease inhibitors.

Chem Biol Drug Des 2018 02 7;91(2):434-447. Epub 2017 Nov 7.

Department of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan.

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http://dx.doi.org/10.1111/cbdd.13090DOI Listing
February 2018
3 Reads
2.485 Impact Factor

Enzyme inhibitory activities an insight into the structure-Activity relationship of biscoumarin derivatives.

Eur J Med Chem 2017 Dec 6;141:386-403. Epub 2017 Oct 6.

Department of Chemistry, Quaid-i-Azam University, 45320, Islamabad, Pakistan. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2017.10.009DOI Listing
December 2017
14 Reads
3.450 Impact Factor

Synthesis, computational studies and enzyme inhibitory kinetics of substituted methyl[2-(4-dimethylamino-benzylidene)-hydrazono)-4-oxo-thiazolidin-5-ylidene]acetates as mushroom tyrosinase inhibitors.

Bioorg Med Chem 2017 11 18;25(21):5929-5938. Epub 2017 Sep 18.

Department of Chemistry, Quaid-i-Azam University, 45320 Islamabad, Pakistan.

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http://dx.doi.org/10.1016/j.bmc.2017.09.009DOI Listing
November 2017
8 Reads
2.793 Impact Factor

Developments in the synthesis of the antiplatelet and antithrombotic drug (S)-clopidogrel.

Chirality 2017 Nov 6;29(11):684-707. Epub 2017 Sep 6.

Department of Chemistry, Quaid-i-Azam University-45320, Islamabad, Pakistan.

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http://dx.doi.org/10.1002/chir.22742DOI Listing
November 2017
13 Reads
1.890 Impact Factor

Applications of Lawesson's reagent in the synthesis of naturally occurring steroids and terpenoids.

J Asian Nat Prod Res 2017 Nov 30;19(11):1114-1123. Epub 2017 Mar 30.

a Department of Chemistry , Quaid-I-Azam University , Islamabad 45320 , Pakistan.

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http://dx.doi.org/10.1080/10286020.2017.1295229DOI Listing
November 2017
1 Read
0.970 Impact Factor

An expedient synthesis of N-(1-(5-mercapto-4-((substituted benzylidene)amino)-4H-1,2,4-triazol-3-yl)-2-phenylethyl)benzamides as jack bean urease inhibitors and free radical scavengers: Kinetic mechanism and molecular docking studies.

Chem Biol Drug Des 2017 Nov 19;90(5):764-777. Epub 2017 Jun 19.

Department of Biological Sciences, College of Natural Sciences, Kongju National University, Gongju, Chungnam, Korea.

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http://dx.doi.org/10.1111/cbdd.12998DOI Listing
November 2017
9 Reads
2.485 Impact Factor

Sensitive and Selective "Turn-On" Chemodosimetric Probes for Fe Based on a Skeleton of 2-Hydroxy-1-Naphthaldehyde.

J Fluoresc 2017 Nov 19;27(6):2213-2221. Epub 2017 Aug 19.

Department of Chemistry, Quaid-I-Azam University, Islamabad, 45320, Pakistan.

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http://dx.doi.org/10.1007/s10895-017-2162-7DOI Listing
November 2017
7 Reads
1.930 Impact Factor

Jack Bean Urease Inhibitors, and Antioxidant Activity Based on Palmitic acid Derived 1-acyl-3- Arylthioureas: Synthesis, Kinetic Mechanism and Molecular Docking Studies.

Drug Res (Stuttg) 2017 Oct 3;67(10):596-605. Epub 2017 Jul 3.

Department of Biological Sciences, College of Natural Sciences, Kongju National University, Gongju, Chungnam, Republic of Korea.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-113832
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http://dx.doi.org/10.1055/s-0043-113832DOI Listing
October 2017
14 Reads
2 Citations

Design and synthesis of 2,6-di(substituted phenyl)thiazolo[3,2-b]-1,2,4-triazoles as α-glucosidase and α-amylase inhibitors, co-relative Pharmacokinetics and 3D QSAR and risk analysis.

Biomed Pharmacother 2017 Oct 4;94:499-513. Epub 2017 Aug 4.

Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan.

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http://dx.doi.org/10.1016/j.biopha.2017.07.139DOI Listing
October 2017
10 Reads
2.023 Impact Factor

Synthesis, molecular docking studies of coumarinyl-pyrazolinyl substituted thiazoles as non-competitive inhibitors of mushroom tyrosinase.

Bioorg Chem 2017 10 12;74:187-196. Epub 2017 Aug 12.

Department of Biological Sciences, College of Natural Sciences, Kongju National University, 56 Gongjudehak-Ro, Gongju, Chungnam 314-701, Republic of Korea.

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https://linkinghub.elsevier.com/retrieve/pii/S00452068173016
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http://dx.doi.org/10.1016/j.bioorg.2017.08.002DOI Listing
October 2017
11 Reads
1 Citation
2.152 Impact Factor

Hybrid Pharmacophoric Approach in the Design and Synthesis of Coumarin Linked Pyrazolinyl as Urease Inhibitors, Kinetic Mechanism and Molecular Docking.

Chem Biodivers 2017 Aug 7;14(8). Epub 2017 Aug 7.

Department of Biological Sciences, College of Natural Sciences, Kongju National University, 56 Gongjudehak-Ro, Gongju, Chungnam, 314-701, Korea.

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http://dx.doi.org/10.1002/cbdv.201700035DOI Listing
August 2017
36 Reads
1 Citation
1.515 Impact Factor

Synthetic approaches towards the multi target drug spironolactone and its potent analogues/derivatives.

Steroids 2017 02 29;118:76-92. Epub 2016 Dec 29.

Department of Chemistry, Quaid-i-Azam University, 45320 Islamabad, Pakistan.

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http://dx.doi.org/10.1016/j.steroids.2016.12.010DOI Listing
February 2017
3 Reads
1 Citation
2.640 Impact Factor

Green Synthesis, Characterization and Electrochemical Behavior of New Thiazole Based Coumarinyl Scaffolds.

J Fluoresc 2016 May 12;26(3):1067-76. Epub 2016 Apr 12.

Department of Chemistry, Quaid-I-Azam University, Islamabad, 45320, Pakistan.

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http://dx.doi.org/10.1007/s10895-016-1795-2DOI Listing
May 2016
3 Reads
1.930 Impact Factor

Top co-authors

Aamer Saeed
Aamer Saeed

Quaid-I-Azam University

28
Pervaiz Ali Channar
Pervaiz Ali Channar

Quaid-I-Azam University

26
Mubashir Hassan
Mubashir Hassan

National Center for Bioinformatics

15
Qamar Abbas
Qamar Abbas

College of Natural Sciences

15
Sung-Yum Seo
Sung-Yum Seo

Kongju National University

14
Hussain Raza
Hussain Raza

University of Birmingham

11
Muhammad Faisal
Muhammad Faisal

University of the Punjab

6
Danish Shahzad
Danish Shahzad

Quaid-i-Azam University

5
Parvez Ali Mahesar
Parvez Ali Mahesar

Quaid-I-Azam University

4