Publications by authors named "Fayaz Ali Larik"

40Publications

Anion Binding Affinity: Acidity versus Conformational Effects.

J Org Chem 2020 Jun 29;85(12):8074-8084. Epub 2020 May 29.

School of Chemistry, University of New South Wales, Sydney, NSW 2052, Australia.

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http://dx.doi.org/10.1021/acs.joc.0c00888DOI Listing
June 2020

New aryl Schiff bases of thiadiazole derivative of ibuprofen as DNA binders and potential anticancer drug candidates.

J Biomol Struct Dyn 2020 May 20:1-17. Epub 2020 May 20.

Healthcare Biotechnology Atta-ur-Rehman School of Applied Biosciences, National University of Science and Technology (NUST), Islamabad, Pakistan.

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http://dx.doi.org/10.1080/07391102.2020.1766569DOI Listing
May 2020

Design, synthesis and biological evaluation of trinary benzocoumarin-thiazoles-azomethines derivatives as effective and selective inhibitors of alkaline phosphatase.

Bioorg Chem 2019 10 23;91:103137. Epub 2019 Jul 23.

Centre for Advanced Drug Research, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2019.103137DOI Listing
October 2019

Synthesis, molecular docking and kinetic studies of novel quinolinyl based acyl thioureas as mushroom tyrosinase inhibitors and free radical scavengers.

Bioorg Chem 2019 09 12;90:103063. Epub 2019 Jun 12.

Department of Biological Sciences, College of Natural Sciences, Kongju National University, 56 Gongjudehak-Ro, Gongju, Chungnam 314-701, Republic of Korea.

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http://dx.doi.org/10.1016/j.bioorg.2019.103063DOI Listing
September 2019

Recent developments and comparison of transformation strategies for organic halides to aldehydes and ketones.

Mol Divers 2020 May 16;24(2):571-592. Epub 2019 May 16.

Department of Chemistry, Quaid-i-Azam University, Islamabad, 45320, Pakistan.

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http://dx.doi.org/10.1007/s11030-019-09956-1DOI Listing
May 2020

Synthesis, Crystal Structure, Hirshfeld Surface Analysis, DFT, and DNA-Binding Studies of (E)-2-(3-Hydroxy-4-Methoxybenzylidene)Hydrazinecarbothioamide.

Appl Biochem Biotechnol 2019 Sep 10;189(1):175-192. Epub 2019 Apr 10.

Department Chemie, Fakultätfür Naturwissenschaften, Universität Paderborn, Warburgerstrasse 100, 33098, Paderborn, Germany.

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http://dx.doi.org/10.1007/s12010-019-03008-yDOI Listing
September 2019

Synthesis of novel ()-1-(2-(2-(4(dimethylamino) benzylidene) hydrazinyl)-4-methylthiazol-5-yl)ethanone derivatives as ecto-5'-nucleotidase inhibitors.

R Soc Open Sci 2018 Sep 12;5(9):180837. Epub 2018 Sep 12.

Centre for Advanced Drug Research, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan.

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http://dx.doi.org/10.1098/rsos.180837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170555PMC
September 2018

Synthesis of sulfonamide, amide and amine hybrid pharmacophore, an entry of new class of carbonic anhydrase II inhibitors and evaluation of chemo-informatics and binding analysis.

Bioorg Chem 2019 05 10;86:624-630. Epub 2019 Feb 10.

Department of Biological Sciences, College of Natural Sciences, Kongju National University, 56 Gongjudehak-Ro, Gongju, Chungnam 32588, Republic of Korea.

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http://dx.doi.org/10.1016/j.bioorg.2019.01.060DOI Listing
May 2019

Investigation on the effect of alkyl chain linked mono-thioureas as Jack bean urease inhibitors, SAR, pharmacokinetics ADMET parameters and molecular docking studies.

Bioorg Chem 2019 05 8;86:473-481. Epub 2019 Feb 8.

Department of Biological Sciences, College of Natural Sciences, Kongju National University, 56 Gongjudehak-Ro, Gongju, Chungnam 314-701, Republic of Korea.

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http://dx.doi.org/10.1016/j.bioorg.2019.02.011DOI Listing
May 2019

One-pot four-component synthesis of thiazolidin-2-imines using Cu/Zn dual catalysis: A new class of acetylcholinesterase inhibitors.

Bioorg Chem 2019 03 5;84:518-528. Epub 2018 Dec 5.

Department of Biological Sciences, College of Natural Science, Kongju National University, Gongju 32588, Republic of Korea.

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http://dx.doi.org/10.1016/j.bioorg.2018.12.002DOI Listing
March 2019

Synthesis, theoretical, spectroscopic and electrochemical DNA binding investigations of 1, 3, 4-thiadiazole derivatives of ibuprofen and ciprofloxacin: Cancer cell line studies.

J Photochem Photobiol B 2018 12 9;189:104-118. Epub 2018 Oct 9.

Healthcare Biotechnology Atta-ur-Rehman School of Applied Biosciences National University of Science and Technology (NUST), Islamabad, Pakistan.

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https://linkinghub.elsevier.com/retrieve/pii/S10111344183068
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http://dx.doi.org/10.1016/j.jphotobiol.2018.10.006DOI Listing
December 2018

Novel 1,3-oxazine-tetrazole hybrids as mushroom tyrosinase inhibitors and free radical scavengers: Synthesis, kinetic mechanism, and molecular docking studies.

Chem Biol Drug Des 2019 02 3;93(2):123-131. Epub 2018 Dec 3.

Department of Biological Sciences, College of Natural Sciences, Kongju National University, Chungnam, Korea.

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http://dx.doi.org/10.1111/cbdd.13352DOI Listing
February 2019

Synthesis of sulfadiazinyl acyl/aryl thiourea derivatives as calf intestinal alkaline phosphatase inhibitors, pharmacokinetic properties, lead optimization, Lineweaver-Burk plot evaluation and binding analysis.

Bioorg Med Chem 2018 07 2;26(12):3707-3715. Epub 2018 Jun 2.

Department of Biological Sciences, College of Natural Sciences, Kongju National University, 56 Gongjudehak-Ro, Gongju, Chungnam 314-701, Republic of Korea.

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http://dx.doi.org/10.1016/j.bmc.2018.06.002DOI Listing
July 2018

Extending the scope of amantadine drug by incorporation of phenolic azo Schiff bases as potent selective inhibitors of carbonic anhydrase II, drug-likeness and binding analysis.

Chem Biol Drug Des 2018 09 26;92(3):1692-1698. Epub 2018 Jun 26.

Department of Biological Sciences, College of Natural Sciences, Kongju National University, Gongju, Chungnam, Korea.

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http://dx.doi.org/10.1111/cbdd.13335DOI Listing
September 2018

New cholinesterase inhibitors for Alzheimer's disease: Structure activity relationship, kinetics and molecular docking studies of 1-butanoyl-3-arylthiourea derivatives.

Int J Biol Macromol 2018 Sep 2;116:144-150. Epub 2018 May 2.

Centre for Advanced Drug Research, COMSATS Institute of Information Technology, Abbottabad 22060, Pakistan. Electronic address:

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http://dx.doi.org/10.1016/j.ijbiomac.2018.05.001DOI Listing
September 2018

Synthetic approaches to access acortatarins, shensongines and pollenopyrroside; potent antioxidative spiro-alkaloids with a naturally rare morpholine moiety.

Fitoterapia 2018 Sep 1;129:366-382. Epub 2018 Apr 1.

Department of Chemistry, Quaid-i-Azam University, 45320 Islamabad, Pakistan.

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http://dx.doi.org/10.1016/j.fitote.2018.03.014DOI Listing
September 2018

Synthesis and Molecular Docking Studies of (E)-4-(Substituted-benzylideneamino)-2H-Chromen-2-one Derivatives: Entry to New Carbonic Anhydrase Class Of Inhibitors.

Drug Res (Stuttg) 2018 Jul 12;68(7):378-386. Epub 2018 Feb 12.

Department of Biological Sciences, College of Natural Sciences, Kongju National University, Gongju, Chungnam, Republic of Korea.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-123998
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http://dx.doi.org/10.1055/s-0043-123998DOI Listing
July 2018

Design, synthesis, kinetic mechanism and molecular docking studies of novel 1-pentanoyl-3-arylthioureas as inhibitors of mushroom tyrosinase and free radical scavengers.

Eur J Med Chem 2017 Dec 29;141:273-281. Epub 2017 Sep 29.

Institut für Anorganische Chemie, J.W.-Goethe-Universität, Max-von-Laue-Str.7, D-60438 Frankfurt/Main, Germany.

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http://dx.doi.org/10.1016/j.ejmech.2017.09.059DOI Listing
December 2017

Enzyme inhibitory activities an insight into the structure-Activity relationship of biscoumarin derivatives.

Eur J Med Chem 2017 Dec 6;141:386-403. Epub 2017 Oct 6.

Department of Chemistry, Quaid-i-Azam University, 45320, Islamabad, Pakistan. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2017.10.009DOI Listing
December 2017

Developments in the synthesis of the antiplatelet and antithrombotic drug (S)-clopidogrel.

Chirality 2017 Nov 6;29(11):684-707. Epub 2017 Sep 6.

Department of Chemistry, Quaid-i-Azam University-45320, Islamabad, Pakistan.

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http://dx.doi.org/10.1002/chir.22742DOI Listing
November 2017

Synthesis, molecular docking studies of coumarinyl-pyrazolinyl substituted thiazoles as non-competitive inhibitors of mushroom tyrosinase.

Bioorg Chem 2017 10 12;74:187-196. Epub 2017 Aug 12.

Department of Biological Sciences, College of Natural Sciences, Kongju National University, 56 Gongjudehak-Ro, Gongju, Chungnam 314-701, Republic of Korea.

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https://linkinghub.elsevier.com/retrieve/pii/S00452068173016
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http://dx.doi.org/10.1016/j.bioorg.2017.08.002DOI Listing
October 2017

Sensitive and Selective "Turn-On" Chemodosimetric Probes for Fe Based on a Skeleton of 2-Hydroxy-1-Naphthaldehyde.

J Fluoresc 2017 Nov 19;27(6):2213-2221. Epub 2017 Aug 19.

Department of Chemistry, Quaid-I-Azam University, Islamabad, 45320, Pakistan.

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http://dx.doi.org/10.1007/s10895-017-2162-7DOI Listing
November 2017

Jack Bean Urease Inhibitors, and Antioxidant Activity Based on Palmitic acid Derived 1-acyl-3- Arylthioureas: Synthesis, Kinetic Mechanism and Molecular Docking Studies.

Drug Res (Stuttg) 2017 Oct 3;67(10):596-605. Epub 2017 Jul 3.

Department of Biological Sciences, College of Natural Sciences, Kongju National University, Gongju, Chungnam, Republic of Korea.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-113832
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http://dx.doi.org/10.1055/s-0043-113832DOI Listing
October 2017

Hybrid Pharmacophoric Approach in the Design and Synthesis of Coumarin Linked Pyrazolinyl as Urease Inhibitors, Kinetic Mechanism and Molecular Docking.

Chem Biodivers 2017 Aug 7;14(8). Epub 2017 Aug 7.

Department of Biological Sciences, College of Natural Sciences, Kongju National University, 56 Gongjudehak-Ro, Gongju, Chungnam, 314-701, Korea.

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http://dx.doi.org/10.1002/cbdv.201700035DOI Listing
August 2017

Applications of Lawesson's reagent in the synthesis of naturally occurring steroids and terpenoids.

J Asian Nat Prod Res 2017 Nov 30;19(11):1114-1123. Epub 2017 Mar 30.

a Department of Chemistry , Quaid-I-Azam University , Islamabad 45320 , Pakistan.

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http://dx.doi.org/10.1080/10286020.2017.1295229DOI Listing
November 2017

Synthetic approaches towards the multi target drug spironolactone and its potent analogues/derivatives.

Steroids 2017 02 29;118:76-92. Epub 2016 Dec 29.

Department of Chemistry, Quaid-i-Azam University, 45320 Islamabad, Pakistan.

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http://dx.doi.org/10.1016/j.steroids.2016.12.010DOI Listing
February 2017

Green Synthesis, Characterization and Electrochemical Behavior of New Thiazole Based Coumarinyl Scaffolds.

J Fluoresc 2016 May 12;26(3):1067-76. Epub 2016 Apr 12.

Department of Chemistry, Quaid-I-Azam University, Islamabad, 45320, Pakistan.

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http://dx.doi.org/10.1007/s10895-016-1795-2DOI Listing
May 2016