Publications by authors named "Farzaneh Hekmatnia"

9 Publications

  • Page 1 of 1

Thyroid volume and nodular and diffuse thyroid diseases by ultrasonography in pregnant women: A case-control study.

J Res Med Sci 2020 20;25:13. Epub 2020 Feb 20.

Department of Medicine, Southend University Hospital, Southend-on Sea, United Kingdom, Southend University Hospital, Westcliff-on-Sea, England, UK.

Background: Currently, it is shown that pregnancy may have an impact on the thyroid that can be leading to pregnancy complications such as abortion, preeclampsia, and preterm delivery. The objective was to compare the thyroid volume, number and characteristics of thyroid nodules, and prevalence of diffuse thyroid diseases in a sample of Iranian pregnant women in the first trimester to nonpregnant women.

Materials And Methods: This case-control study was conducted on 298 pregnant and 290 nonpregnant women. Thyroid volume, maximum diameter of thyroid nodules and prevalence of moderate to highly suspicious thyroid nodules, Hashimoto's appearance and goiter were assessed using thyroid ultrasonography. Antithyroperoxidase (TPO) antibodies were measured if the sonographic features were highly suggested for Hashimoto's thyroiditis.

Results: The mean of total thyroid volume in pregnant and nonpregnant women was 6 and 6.5 ml, respectively ( = 0.053), and the median (interquartile range) was 6.2 and 5.5, respectively. Nodules were observed in 16.4% of pregnant and 16.6% of nonpregnant women ( = 0.845). Hashimoto's thyroiditis was detected in 6.7% of pregnant and 12.4% of nonpregnant women ( = 0.013). Anti-TPO antibodies were detected in 5% of pregnant and 9.3% of nonpregnant women ( = 0.034).

Conclusion: The thyroid volume and nodule characteristics in the first trimester of pregnancy were similar to nonpregnant women. Hashimoto's thyroiditis and anti-TPO antibodies in pregnant women were significantly lower than in nonpregnant women.
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http://dx.doi.org/10.4103/jrms.JRMS_42_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053162PMC
February 2020

A Large Primary Subcutaneous Hydatid Cyst in Proximal Thigh: An Unusual Localization.

Adv Biomed Res 2018 27;7:50. Epub 2018 Mar 27.

Department of Radiology, Isfahan University of Medical Sciences, Isfahan, Iran.

Primary muscular hydatidosis is a very rare condition with an incidence of 1%-4% in endemic regions. This case report describes an unusual location of hydatid cyst in the sartorius muscle and the application of imaging in its preoperative diagnosis, choosing a treatment strategy, and monitoring.
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http://dx.doi.org/10.4103/2277-9175.228622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887698PMC
March 2018

A bilobed testicle diagnosed with ultrasound in an 18-year-old boy.

J Res Med Sci 2016 1;21:62. Epub 2016 Aug 1.

Department of Radiology and Imaging, Isfahan University of Medical Sciences, Isfahan, Iran.

Bilobed testicle is a very rare congenital malformation with an unknown etiology. Herein, we report an 18-year-old boy presented with a right-bilobed testicle mimicking a testicular tumor. The present case highlights the importance of considering bilobed testicle as a valuable differential diagnosis of testicular mass to prevent unnecessary surgery. Furthermore, the case could provide more information about presentation and management of bilobed testicle.
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http://dx.doi.org/10.4103/1735-1995.187337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122000PMC
August 2016

A case report of osteochondroma with unusual clinical and imaging presentation.

Adv Biomed Res 2015 6;4. Epub 2015 Jan 6.

Processing and Signal Research Center, Department of Radiology, Alzahra Hospital, Isfahan Medical University, Isfahan, Iran.

Osteochondroma or exostosis is a bony developmental anomaly, which arises from exophytic outgrowth on bone surfaces in a characteristic manner. Osteochondroma is asymptomatic and grows away from the nearby joint. This paper reports an unusual presentation of osteochondroma in which the patient was surprisingly completely symptomatic. The lesion grew toward the nearby joint and the radiographic findings were not compatible with surgical findings.
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http://dx.doi.org/10.4103/2277-9175.148258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300597PMC
January 2015

Solitary giant neurofibroma of thigh.

Adv Biomed Res 2014 31;3:158. Epub 2014 Jul 31.

Department of Medicine, St. George Medical School, University of London, London, UK.

Neurofibromas are rare, benign, nerve sheath tumors in the peripheral nervous system. The solitary type is found in those who do not have neurofibromatosis. Solitary neurofibromas are too rare in the giant type. We report a rare case of a solitary giant neurofibroma of the anterior right thigh. The diagnostic criteria, characteristics of imaging studies, and operative approach are represented.
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http://dx.doi.org/10.4103/2277-9175.137872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162075PMC
September 2014

Prevalence of hippocampal morphologic variants between healthy elderly subjects and patients with Alzheimer's disease.

Adv Biomed Res 2014 27;3:59. Epub 2014 Jan 27.

Radiologist, Tehran, Iran.

Background: Alzheimer's disease (AD) is a neurodegenerative disease with atrophic changes in the temporal lobe. Enlargement of cerebrospinal fluid (CSF) spaces, hippocampal sulcus (HS) enlargement, or an increase in the number or size of hippocampal cavities (HCs) could be associated with medial temporal lobe atrophy (MTA). In this study, we assessed the relation of these CSF spaces with AD.

Materials And Methods: A total 36 demented patients with diagnosis of Alzheimer (Mini-Mental State Examination (MMSE) ≤25) and 36 non-demented elderly individuals were referred for basic magnetic resonance imaging (MRI) before initiating anti-dementia therapy in the demented group. Two observers assessed the maximal HS width, as well as the occurrence, number, and size of HCs, and the visual rating score of MTA on magnified coronal high-resolution T1-weighted MR images.

Results: The findings of our study indicate that the presence of hippocampal cavity (HC) (especially in the left side) and medial temporal lobe atrophy in demented patients was significantly higher in comparison with non-demented elderly subjects (P ≤ 0.05). There was a significant relationship between MTA and HS width (P = 0.003, r = 0.00323), and it also had a trend to be significant with size of HCs (P = 0.08, r = 0.00314). A correlation between MTA and number of HCs was not detected.

Conclusion: HS width is associated with MTA in patients with AD. It may serve as a measure to evaluate MTA for identifying individuals at particularly high risk for Alzheimer progression, and could be employed for selecting subjects for clinical trials or for treatment decisions.
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http://dx.doi.org/10.4103/2277-9175.125817DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950805PMC
March 2014

Diagnostic accuracy of magnetic resonance voiding cystourethrography for detecting vesico-ureteral reflux in children and adolescents.

J Res Med Sci 2013 Jan;18(1):31-6

Departments of Radiology, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: The purpose of the present study is to determine the accuracy of magnetic resonance voiding cystourethrography (MRVCUG) for diagnosis of vesicoureteral reflux (VUR) in children and adolescents with recurrent urinary tract infection (UTI).

Materials And Methods: During the cross-sectional study from May 2009 to June 2011, 30 patients' (60 kidney-ureter units) MRVCUG findings by 1.5 T magnetic resonance imaging (MRI) were compared with voiding cystourethrography (VCUG) findings in patients with urinary tract infection. The sensitivity, specificity, positive and negative predictive values for MRVCUG were calculated.

Findings: The sensitivity, specificity, positive and negative predictive values and accuracy for MRVCUG for detecting VUR were respectively 92.68% (95% CI: 80.57-97.48%), 68.42% (95% CI: 46.01-84.64%), 86.36% (95% CI: 71.95-94.33%), 81.25% (95% CI: 53.69-95.02%), and 85% (95% CI: 80.40-89.60%. The level of agreement between MRVCUG and VCUG findings for diagnosis VUR was very good (P < 0.001, according to Cohen's kappa value = 0.638). Studying correlation of low grade VUR (grade I and II) and high grade VUR (grade III-V) showed a very good agreement between MRVCUG and VCUG findings (P < 0.001, Cohen's kappa value = 0.754).

Conclusion: MRVCUG could accurately reveal the presence and severity of VUR, especially in cases with high-grade (grade III-V) VUR in both children and adolescents.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719223PMC
January 2013

The comparative study on diagnostic validity of cerebral aneurysm by computed tomography angiography versus digital subtraction angiography after subarachnoid hemorrhage.

J Res Med Sci 2011 Aug;16(8):1020-5

Associated Professor of Neurosurgery, Department of Neurosurgery, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: In order to declare the preoperative diagnostic value of brain aneurysms, two radiological modalities, computed tomographic angiography and digital subtraction angiography were compared.

Methods: In this descriptive analytic study, diagnostic value of computed tomographic angiography (CTA) was compared with digital subtraction angiography (DSA). Sensitivity, specificity, positive and negative predictive values were calculated and compared between the two modalities. All data were analyzed with SPSS software, version 16.

Results: Mean age of patients was 49.5 ± 9.13 years. 57.9 % of subjects were female. CTA showed 89% sensitivity and 100% specificity whereas DSA demonstrated 74% sensitivity and 100% specificity. Positive predictive value of both methods was 100%, but negative predictive value of CTA and DSA was 85% and 69%, respectively.

Conclusions: Based on our data, CTA is a valuable diagnostic modality for detection of brain aneurysm and subarachnoid hemorrhage.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263078PMC
August 2011

A case report of cemento-ossifying fibroma presenting as a mass of the ethmoid sinus.

J Res Med Sci 2011 Feb;16(2):224-8

Associate Professor of Radiology, Image Processing and Signal Research Center, Department of Radiology, Al-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.

Cemento-ossifying fibroma is a lesion containing both fibrous and osseous components. Such lesions include fibrous dysplasia, ossifying fibroma, cemento-ossifying fibroma and cementifying fibroma. Periodontal membrane is the origin of fibro-osseous lesions other than fibrous dysplasia.Here a clinical case of a young woman referred for evaluation of a mass in the right side of face between eye and nose is presented. The first time she noticed the mass was 2 years ago and was growing larger inwards. She was treated with surgical resection.In this case of a cemento-ossifying fibroma, histological interpretation was critical, and was the basis of correct treatment.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214308PMC
February 2011