Farshid Guilak

Farshid Guilak

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Farshid Guilak

Publications by authors named "Farshid Guilak"

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Optimization of Meniscus Cell Transduction Using Lentivirus and Adeno-Associated Virus for Gene Editing and Tissue Engineering Applications.

Cartilage 2019 Oct 14:1947603519880321. Epub 2019 Oct 14.

Department of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC, USA.

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http://dx.doi.org/10.1177/1947603519880321DOI Listing
October 2019

miR-892b Inhibits Hypertrophy by Targeting KLF10 in the Chondrogenesis of Mesenchymal Stem Cells.

Mol Ther Nucleic Acids 2019 Sep 13;17:310-322. Epub 2019 Jun 13.

Research Institute for Integrative Regenerative Biomedical Engineering, Dongguk University, Goyang 10326, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.omtn.2019.05.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612925PMC
September 2019

Combined Experimental Approach and Finite Element Modeling of Small Molecule Transport Through Joint Synovium to Measure Effective Diffusivity.

J Biomech Eng 2019 Sep 1. Epub 2019 Sep 1.

Department of Biomedical Engineering, Washington University in St. Louis, Whitaker Hall, 1 Brookings Dr., St. Louis, MO, 63130.

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http://dx.doi.org/10.1115/1.4044892DOI Listing
September 2019

Chondrogenic, hypertrophic, and osteochondral differentiation of human mesenchymal stem cells on three-dimensionally woven scaffolds.

J Tissue Eng Regen Med 2019 Aug 18;13(8):1453-1465. Epub 2019 Jul 18.

Institute for Medical Engineering and Science, David H. Koch Institute for Integrative Cancer Research, and Media Lab, Massachusetts Institute of Technology, Cambridge, MA.

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http://dx.doi.org/10.1002/term.2899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715532PMC
August 2019

Genome Engineering for Osteoarthritis: From Designer Cells to Disease-Modifying Drugs.

Tissue Eng Regen Med 2019 Aug 5;16(4):335-343. Epub 2019 Jan 5.

1Department of Orthopaedic Surgery, Washington University in St. Louis, 1 Brookings Dr, St. Louis, MO 63130 USA.

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http://dx.doi.org/10.1007/s13770-018-0172-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675820PMC
August 2019

Stem cell-derived extracellular vesicles attenuate the early inflammatory response after tendon injury and repair.

J Orthop Res 2019 Jul 9. Epub 2019 Jul 9.

Department of Orthopaedic Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8233, St. Louis, Missouri.

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http://dx.doi.org/10.1002/jor.24406DOI Listing
July 2019

Designer Stem Cells: Genome Engineering and the Next Generation of Cell-Based Therapies.

J Orthop Res 2019 Jun 2;37(6):1287-1293. Epub 2019 May 2.

Department of Medicine, Division of Rheumatology, Washington University, St. Louis, Missouri.

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http://dx.doi.org/10.1002/jor.24304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546536PMC
June 2019

Journal of Orthopaedic Research: Special Issue on Stem Cells.

J Orthop Res 2019 Jun 17;37(6):1209-1211. Epub 2019 May 17.

Steadman Philippon Research Institute, Vail, Colorado.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/jor.24338
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http://dx.doi.org/10.1002/jor.24338DOI Listing
June 2019

A Synthetic Gene Circuit for Self-Regulating Delivery of Biologic Drugs in Engineered Tissues.

Tissue Eng Part A 2019 05;25(9-10):809-820

1 Department of Orthopedic Surgery, Washington University in Saint Louis, Saint Louis, Missouri.

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http://dx.doi.org/10.1089/ten.TEA.2019.0027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533793PMC
May 2019

Cell migration: implications for repair and regeneration in joint disease.

Nat Rev Rheumatol 2019 Mar;15(3):167-179

McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, Washington University, St Louis, MO, USA.

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http://dx.doi.org/10.1038/s41584-018-0151-0DOI Listing
March 2019

Effects of dietary fatty acid content on humeral cartilage and bone structure in a mouse model of diet-induced obesity.

J Orthop Res 2019 Mar 12;37(3):779-788. Epub 2019 Feb 12.

Department of Orthopaedic Surgery, Washington University, Couch Biomedical Research Bldg., Room 3121, Campus Box 8233, Saint Louis, Missouri 63110.

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http://dx.doi.org/10.1002/jor.24219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662729PMC
March 2019

Physiologic and pathologic effects of dietary free fatty acids on cells of the joint.

Ann N Y Acad Sci 2019 Mar 15;1440(1):36-53. Epub 2019 Jan 15.

Department of Orthopaedic Surgery, Washington University, St. Louis, Missouri.

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http://dx.doi.org/10.1111/nyas.13999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420352PMC
March 2019

High-depth transcriptomic profiling reveals the temporal gene signature of human mesenchymal stem cells during chondrogenesis.

FASEB J 2019 01 9;33(1):358-372. Epub 2018 Jul 9.

Department of Orthopedic Surgery, Washington University in St. Louis, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1096/fj.201800534RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355072PMC
January 2019

Genetic Engineering of Mesenchymal Stem Cells for Differential Matrix Deposition on 3D Woven Scaffolds.

Tissue Eng Part A 2018 10 13;24(19-20):1531-1544. Epub 2018 Jul 13.

1 Department of Orthopaedic Surgery, Washington University in Saint Louis , Saint Louis, Missouri.

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http://dx.doi.org/10.1089/ten.TEA.2017.0510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198766PMC
October 2018

Osteoarthritis as a disease of the cartilage pericellular matrix.

Matrix Biol 2018 10 22;71-72:40-50. Epub 2018 May 22.

Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S0945053X183018
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http://dx.doi.org/10.1016/j.matbio.2018.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146061PMC
October 2018

Composite Cellularized Structures Created from an Interpenetrating Polymer Network Hydrogel Reinforced by a 3D Woven Scaffold.

Macromol Biosci 2018 10 24;18(10):e1800140. Epub 2018 Jul 24.

Center of Regenerative Medicine, Washington University, Campus Box 8233, St. Louis, MO, 63110, USA.

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http://dx.doi.org/10.1002/mabi.201800140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687075PMC
October 2018

Obesity alters the in vivo mechanical response and biochemical properties of cartilage as measured by MRI.

Arthritis Res Ther 2018 Oct 17;20(1):232. Epub 2018 Oct 17.

Department of Orthopaedic Surgery, Duke University, Box 3093, Duke University Medical Center, Durham, NC, 27710, USA.

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http://dx.doi.org/10.1186/s13075-018-1727-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235204PMC
October 2018

Regulation of decellularized tissue remodeling via scaffold-mediated lentiviral delivery in anatomically-shaped osteochondral constructs.

Biomaterials 2018 09 30;177:161-175. Epub 2018 May 30.

Washington University in Saint Louis, Saint Louis, MO 63110, USA; Shriners Hospitals for Children - St. Louis, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2018.04.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082159PMC
September 2018

Canine hip dysplasia: A natural animal model for human developmental dysplasia of the hip.

J Orthop Res 2018 07 27;36(7):1807-1817. Epub 2018 Feb 27.

Department of Orthopaedic Surgery, School of Medicine, Musculoskeletal Research Center, Washington University, 660 S. Euclid, Campus Box 8233, Saint Louis, Missouri, 63110.

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http://dx.doi.org/10.1002/jor.23828DOI Listing
July 2018

CXCL10 is upregulated in synovium and cartilage following articular fracture.

J Orthop Res 2018 04 20;36(4):1220-1227. Epub 2017 Nov 20.

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, 27710, North Carolina.

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http://dx.doi.org/10.1002/jor.23735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851826PMC
April 2018

Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cells.

Stem Cell Res Ther 2018 03 9;9(1):61. Epub 2018 Mar 9.

Department of Orthopaedic Surgery, Washington University, St. Louis, MO, USA.

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http://dx.doi.org/10.1186/s13287-018-0797-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845143PMC
March 2018

Dynamics and mechanisms of intracellular calcium waves elicited by tandem bubble-induced jetting flow.

Proc Natl Acad Sci U S A 2018 01 27;115(3):E353-E362. Epub 2017 Dec 27.

Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708;

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http://dx.doi.org/10.1073/pnas.1713905115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776977PMC
January 2018

Genome Engineering for Personalized Arthritis Therapeutics.

Trends Mol Med 2017 10 5;23(10):917-931. Epub 2017 Sep 5.

Department of Orthopedic Surgery, Washington University, St. Louis, MO 63110, USA; Shriners Hospitals for Children - St. Louis, St. Louis, MO 63110, USA; Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA; Cytex Therapeutics, Inc., Durham, NC 27705, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2017.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657581PMC
October 2017

Regulation of human nucleus pulposus cells by peptide-coupled substrates.

Acta Biomater 2017 06 20;55:100-108. Epub 2017 Apr 20.

Department of Biomedical Engineering, Washington University in St. Louis, United States; Department of Orthopaedic Surgery, Washington University in St. Louis, United States. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2017.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536110PMC
June 2017

CRISPR/Cas9 Editing of Murine Induced Pluripotent Stem Cells for Engineering Inflammation-Resistant Tissues.

Arthritis Rheumatol 2017 05 31;69(5):1111-1121. Epub 2017 Mar 31.

Washington University and Shriners Hospitals for Children, St. Louis, Missouri.

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http://dx.doi.org/10.1002/art.39982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406241PMC
May 2017

Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs.

Stem Cell Reports 2017 05 27;8(5):1202-1213. Epub 2017 Apr 27.

Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA; Cytex Therapeutics, Inc., Durham, NC 27705, USA; Department of Orthopaedic Surgery, Washington University, St. Louis, MO 63110, USA; Shriners Hospitals for Children - St. Louis, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.03.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425682PMC
May 2017

Mechanical Signals as Regulators of Cartilage Degeneration and Regeneration.

J Am Acad Orthop Surg 2017 04;25(4):e87-e89

From the Department of Orthopaedic Surgery and the Musculoskeletal Research Center, Washington University School of Medicine at Barnes-Jewish Hospital, St. Louis, MO (Dr. Rai), the Department of Musculoskeletal Regeneration, AO Research Institute, Davos, Switzerland (Dr. Stoddart), and the Department of Orthopaedic Surgery, the Musculoskeletal Research Center, the Department of Developmental Biology, the Center of Regenerative Medicine, and the Department of Biomedical Engineering, Washington University School of Medicine at Barnes-Jewish Hospital, St. Louis and Shriners Hospitals for Children, St. Louis (Dr. Guilak).

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http://Insights.ovid.com/crossref?an=00124635-201704000-0001
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http://dx.doi.org/10.5435/JAAOS-D-16-00938DOI Listing
April 2017

New tools for Content Innovation and data sharing: Enhancing reproducibility and rigor in biomechanics research.

Authors:
Farshid Guilak

J Biomech 2017 03 10;54:1-3. Epub 2017 Feb 10.

Washington University and Shriners Hospitals for Children - St. Louis, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jbiomech.2017.01.044DOI Listing
March 2017

Serum and synovial fluid lipidomic profiles predict obesity-associated osteoarthritis, synovitis, and wound repair.

Sci Rep 2017 03 20;7:44315. Epub 2017 Mar 20.

Department of Orthopaedic Surgery, Washington University, St. Louis MO, 63110, USA.

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http://dx.doi.org/10.1038/srep44315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357837PMC
March 2017

On the Functional Role of Valve Interstitial Cell Stress Fibers: A Continuum Modeling Approach.

J Biomech Eng 2017 02;139(2)

W. A. "Tex" Moncrief, Jr. Simulation-Based Engineering Science Chair I Center for Cardiovascular Simulation, Institute for Computational Engineering and Sciences, Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX 78712 e-mail:

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http://dx.doi.org/10.1115/1.4035557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395916PMC
February 2017

Emerging roles for long noncoding RNAs in skeletal biology and disease.

Connect Tissue Res 2017 01 2;58(1):116-141. Epub 2016 Jun 2.

a Department of Orthopaedic Surgery , Washington University School of Medicine , St Louis , MO , USA.

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http://dx.doi.org/10.1080/03008207.2016.1194406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301950PMC
January 2017

Loss of stiffness in collagen-rich uterine fibroids after digestion with purified collagenase Clostridium histolyticum.

Am J Obstet Gynecol 2016 Nov 10;215(5):596.e1-596.e8. Epub 2016 May 10.

Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, NC; Department of Pathology, Duke University School of Medicine, Durham, NC.

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http://dx.doi.org/10.1016/j.ajog.2016.05.006DOI Listing
November 2016

Fabrication of anatomically-shaped cartilage constructs using decellularized cartilage-derived matrix scaffolds.

Biomaterials 2016 Jun 9;91:57-72. Epub 2016 Mar 9.

Department of Orthopaedic Surgery, Washington University, St. Louis, MO, 63110, United States; Department of Developmental Biology, Washington University, St. Louis, MO, 63110, United States; Department of Biomedical Engineering, Washington University, St. Louis, MO, 63110, United States; Shriners Hospitals for Children - St. Louis Hospital, 3210 McKinley Research Building, St. Louis, MO, 63110, United States. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2016.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822340PMC
June 2016

Dedifferentiated Human Articular Chondrocytes Redifferentiate to a Cartilage-Like Tissue Phenotype in a Poly(ε-Caprolactone)/Self-Assembling Peptide Composite Scaffold.

Materials (Basel) 2016 Jun 17;9(6). Epub 2016 Jun 17.

Tissue Engineering Laboratory, Bioengineering Department, IQS School of Engineering, Ramon Llull University, Via Augusta 390, Barcelona 08017, Spain.

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http://dx.doi.org/10.3390/ma9060472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456812PMC
June 2016

Morphogenetic Implications of Peristalsis-Driven Fluid Flow in the Embryonic Lung.

PLoS One 2015 6;10(7):e0132015. Epub 2015 Jul 6.

Department of Mathematics, North Carolina State University, Raleigh, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132015PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493131PMC
April 2016

Unraveling the mechanism by which TRPV4 mutations cause skeletal dysplasias.

Rare Dis 2014 30;2(1):e962971. Epub 2014 Oct 30.

Department of Neurology and Duke University Clinics for Pain and Palliative Care; Duke University Medical Center ; Durham, NC USA.

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http://dx.doi.org/10.4161/2167549X.2014.962971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755236PMC
March 2016

Universally Conserved Relationships between Nuclear Shape and Cytoplasmic Mechanical Properties in Human Stem Cells.

Sci Rep 2016 Mar 15;6:23047. Epub 2016 Mar 15.

Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.

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http://dx.doi.org/10.1038/srep23047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792134PMC
March 2016

Reply to "Does progranulin account for the opposite effects of etanercept and infliximab/adalimumab in osteoarthritis?" by Wei et al.

J Orthop Res 2016 Jan 8;34(1):15-6. Epub 2015 Dec 8.

Laszlo Ormandy Professor and Vice-Chair of Orthopaedic Surgery, Departments of Orthopaedic Surgery, Biomedical Engineering, Mechanical Engineering & Materials Science, and Cell Biology.

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http://dx.doi.org/10.1002/jor.23095DOI Listing
January 2016

Dietary fatty acid content regulates wound repair and the pathogenesis of osteoarthritis following joint injury.

Ann Rheum Dis 2015 Nov 10;74(11):2076-83. Epub 2014 Jul 10.

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina, USA Department of Biomedical Engineering, Duke University Medical Center, Durham, North Carolina, USA Department of Cell Biology, Duke University Medical Center, Durham, North Carolina, USA.

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http://ard.bmj.com/content/early/2014/07/08/annrheumdis-2014
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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2014-20560
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http://dx.doi.org/10.1136/annrheumdis-2014-205601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363043PMC
November 2015

Therapeutic opportunities to prevent post-traumatic arthritis: Lessons from the natural history of arthritis after articular fracture.

J Orthop Res 2015 Sep 7;33(9):1266-77. Epub 2015 Jun 7.

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina.

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http://dx.doi.org/10.1002/jor.22940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529755PMC
September 2015

Extracellular Calcium Modulates Chondrogenic and Osteogenic Differentiation of Human Adipose-Derived Stem Cells: A Novel Approach for Osteochondral Tissue Engineering Using a Single Stem Cell Source.

Tissue Eng Part A 2015 Sep 13;21(17-18):2323-33. Epub 2015 Jul 13.

1 Joint Department of Biomedical Engineering at University of North Carolina at Chapel Hill, North Carolina State University , Raleigh, North Carolina.

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http://dx.doi.org/10.1089/ten.TEA.2014.0572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556087PMC
September 2015

Aligned multilayered electrospun scaffolds for rotator cuff tendon tissue engineering.

Acta Biomater 2015 Sep 14;24:117-26. Epub 2015 Jun 14.

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2015.06.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560626PMC
September 2015

3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures.

Adv Mater 2015 Jul 1;27(27):4035-40. Epub 2015 Jun 1.

Department of Mechanical Engineering and Material Science, Duke University, Durham, NC, 27708, USA.

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http://dx.doi.org/10.1002/adma.201501099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849481PMC
July 2015

3D Printing: 3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures.

Adv Mater 2015 Jul;27(27):4034

Department of Mechanical Engineering and Material Science, Duke University, Durham, NC, 27708, USA.

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http://dx.doi.org/10.1002/adma.201570182DOI Listing
July 2015

Enhanced MyoD-induced transdifferentiation to a myogenic lineage by fusion to a potent transactivation domain.

ACS Synth Biol 2015 Jun 31;4(6):689-99. Epub 2014 Dec 31.

§Department of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina 27710, United States.

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http://dx.doi.org/10.1021/sb500322uDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475448PMC
June 2015

Mechanobiology of the meniscus.

J Biomech 2015 Jun 9;48(8):1469-78. Epub 2015 Feb 9.

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, United States.

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http://dx.doi.org/10.1016/j.jbiomech.2015.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442061PMC
June 2015

Tendon mechanobiology: Current knowledge and future research opportunities.

J Orthop Res 2015 Jun 27;33(6):813-22. Epub 2015 Apr 27.

Laboratory for Comparative Orthopaedic Research, College of Veterinary Medicine Michigan State University, East Lansing, Michigan.

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http://dx.doi.org/10.1002/jor.22871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524513PMC
June 2015

TRPV4 as a therapeutic target for joint diseases.

Naunyn Schmiedebergs Arch Pharmacol 2015 Apr 18;388(4):437-50. Epub 2014 Dec 18.

Department of Orthopaedic Surgery, Duke University Medical Center, DUMC 3093, Durham, NC, 27710, USA.

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http://dx.doi.org/10.1007/s00210-014-1078-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361386PMC
April 2015

Life-long caloric restriction does not alter the severity of age-related osteoarthritis.

Age (Dordr) 2014 1;36(4):9669. Epub 2014 Jul 1.

Department of Orthopaedic Surgery, Duke University Medical Center, 375 Medical Sciences Research Bldg, 3093, Durham, NC, 27710, USA.

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http://dx.doi.org/10.1007/s11357-014-9669-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150885PMC
March 2015

Proteomic differences between male and female anterior cruciate ligament and patellar tendon.

PLoS One 2014 12;9(5):e96526. Epub 2014 May 12.

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina, United States of America; Department of Biomedical Engineering, Duke University Medical Center, Durham, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0096526PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018326PMC
January 2015

Micro-scale and meso-scale architectural cues cooperate and compete to direct aligned tissue formation.

Biomaterials 2014 Dec 26;35(38):10015-24. Epub 2014 Sep 26.

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2014.08.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345291PMC
December 2014

Electrospun cartilage-derived matrix scaffolds for cartilage tissue engineering.

J Biomed Mater Res A 2014 Nov 9;102(11):3998-4008. Epub 2014 Jan 9.

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina, 27710; Department of Biomedical Engineering, Duke University Medical Center, Durham, North Carolina, 27710.

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http://dx.doi.org/10.1002/jbm.a.35068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063882PMC
November 2014

Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage.

Proc Natl Acad Sci U S A 2014 Nov 10;111(47):E5114-22. Epub 2014 Nov 10.

Departments of Neurology, Neurobiology, and Clinics for Pain and Palliative Care, Duke University Medical Center, Durham, NC 27710;

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http://dx.doi.org/10.1073/pnas.1414298111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250098PMC
November 2014

High resistance of the mechanical properties of the chondrocyte pericellular matrix to proteoglycan digestion by chondroitinase, aggrecanase, or hyaluronidase.

J Mech Behav Biomed Mater 2014 Oct 3;38:183-97. Epub 2013 Oct 3.

Department of Orthopaedic Surgery, Duke University Medical Center, USA; Department of Biomedical Engineering, Duke University, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jmbbm.2013.09.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975804PMC
October 2014

The structure and function of the pericellular matrix of articular cartilage.

Matrix Biol 2014 Oct 27;39:25-32. Epub 2014 Aug 27.

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA; Department of Biomedical Engineering, Duke University Medical Center, Durham, NC, USA; Department of Cell Biology, Duke University Medical Center, Durham, NC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2014.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198577PMC
October 2014

The mechanobiology of articular cartilage: bearing the burden of osteoarthritis.

Curr Rheumatol Rep 2014 Oct;16(10):451

Department of Orthopaedic Surgery, Duke University Medical Center, 375 Medical Sciences Research Bldg., Box 3093, Durham, NC, 27710, USA.

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http://dx.doi.org/10.1007/s11926-014-0451-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682660PMC
October 2014

Stem cell therapies for knee cartilage repair: the current status of preclinical and clinical studies.

Am J Sports Med 2014 Sep 12;42(9):2253-61. Epub 2013 Nov 12.

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina.

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http://dx.doi.org/10.1177/0363546513508744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019709PMC
September 2014

Tissue-engineered cartilage with inducible and tunable immunomodulatory properties.

Biomaterials 2014 Jul 22;35(22):5921-31. Epub 2014 Apr 22.

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA; Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2014.03.073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047672PMC
July 2014

Follistatin in chondrocytes: the link between TRPV4 channelopathies and skeletal malformations.

FASEB J 2014 Jun 27;28(6):2525-37. Epub 2014 Feb 27.

Department of Neurology, Duke University Clinics for Pain and Palliative Care, Duke University Medical Center, Durham, North Carolina, USA; and

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http://dx.doi.org/10.1096/fj.13-245936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021446PMC
June 2014

Functional tissue engineering: Ten more years of progress.

J Biomech 2014 Jun 12;47(9):1931-2. Epub 2014 Apr 12.

Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, The Netherlands.

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http://dx.doi.org/10.1016/j.jbiomech.2014.04.003DOI Listing
June 2014

Biomechanics and mechanobiology in functional tissue engineering.

J Biomech 2014 Jun 26;47(9):1933-40. Epub 2014 Apr 26.

Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, The Netherlands.

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http://dx.doi.org/10.1016/j.jbiomech.2014.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051419PMC
June 2014

Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage.

Proc Natl Acad Sci U S A 2014 Mar 18;111(9):E798-806. Epub 2014 Feb 18.

Departments of Orthopaedic Surgery and Cell Biology, Duke University Medical Center, Durham, NC 27710.

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http://dx.doi.org/10.1073/pnas.1321744111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948308PMC
March 2014

Interaction of lubricin with type II collagen surfaces: adsorption, friction, and normal forces.

J Biomech 2014 Feb 11;47(3):659-66. Epub 2013 Dec 11.

Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA; Center for Biologically Inspired Materials and Material Systems, Duke University, Durham, NC 27708, USA; Center for Biomolecular and Tissue Engineering, Duke University, Durham, NC 27708, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jbiomech.2013.11.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925751PMC
February 2014

Viscoelastic properties of a synthetic meniscus implant.

J Mech Behav Biomed Mater 2014 Jan 3;29:42-55. Epub 2013 Sep 3.

Research and Development Center, Active Implants, 43 Hamelacha Street, Netanya 42505, Israel.

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http://dx.doi.org/10.1016/j.jmbbm.2013.08.021DOI Listing
January 2014

TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading.

Proc Natl Acad Sci U S A 2014 Jan 13;111(4):1316-21. Epub 2014 Jan 13.

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710.

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http://dx.doi.org/10.1073/pnas.1319569111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910592PMC
January 2014

Multilayered electrospun scaffolds for tendon tissue engineering.

Tissue Eng Part A 2013 Dec 29;19(23-24):2594-604. Epub 2013 Aug 29.

1 Department of Orthopaedic Surgery, Duke University Medical Center , Durham, North Carolina.

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http://online.liebertpub.com/doi/abs/10.1089/ten.tea.2013.01
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http://dx.doi.org/10.1089/ten.TEA.2013.0165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856877PMC
December 2013

Composite three-dimensional woven scaffolds with interpenetrating network hydrogels to create functional synthetic articular cartilage.

Adv Funct Mater 2013 Dec;23(47):5833-5839

Departments of Orthopaedic Surgery and Mechanical Engineering & Materials Science, Duke University Medical Center, Durham North Carolina, 27710 USA.

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http://dx.doi.org/10.1002/adfm.201300483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933181PMC
December 2013

The effects of crosslinking of scaffolds engineered from cartilage ECM on the chondrogenic differentiation of MSCs.

Biomaterials 2013 Jul 2;34(23):5802-12. Epub 2013 May 2.

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.biomaterials.2013.04.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660461PMC
July 2013

Mechanical regulation of chondrogenesis.

Stem Cell Res Ther 2013 Jul 1;4(4):61. Epub 2013 Jul 1.

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http://dx.doi.org/10.1186/scrt211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707042PMC
July 2013