Farhad R Danesh

Farhad R Danesh

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Farhad R Danesh

Publications by authors named "Farhad R Danesh"

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Summary of the International Conference on Onco-Nephrology: an emerging field in medicine.

Kidney Int 2019 Sep 31;96(3):555-567. Epub 2019 May 31.

Department of Translational Medical Sciences, University Luigi Vanvitelli, Naples, Italy; BioGeM Institute, Ariano Irpino, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2019.04.043DOI Listing
September 2019

MTHFD2 links RNA methylation to metabolic reprogramming in renal cell carcinoma.

Oncogene 2019 Aug 9;38(34):6211-6225. Epub 2019 Jul 9.

Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1038/s41388-019-0869-4DOI Listing
August 2019

Drp1S600 phosphorylation regulates mitochondrial fission and progression of nephropathy in diabetic mice.

J Clin Invest 2019 05 7;129(7):2807-2823. Epub 2019 May 7.

Section of Nephrology, The University of Texas at MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1172/JCI127277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597204PMC
May 2019

Values and Limitations of Targeting lncRNAs in Diabetic Nephropathy.

Diabetes 2018 04;67(4):552-553

Section of Nephrology, The University of Texas MD Anderson Cancer Center, Houston, TX

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http://dx.doi.org/10.2337/dbi17-0052DOI Listing
April 2018

Real-time in vivo mitochondrial redox assessment confirms enhanced mitochondrial reactive oxygen species in diabetic nephropathy.

Kidney Int 2017 11 26;92(5):1282-1287. Epub 2017 Jul 26.

Section of Nephrology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Department of Pharmacology, Baylor College of Medicine, Houston, Texas, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2017.05.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656393PMC
November 2017

The hallmarks of mitochondrial dysfunction in chronic kidney disease.

Kidney Int 2017 11;92(5):1051-1057

Section of Nephrology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, Texas, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2017.05.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667560PMC
November 2017

β-adrenergic receptors in inflammation and vascular complications of diabetes.

Kidney Int 2017 07;92(1):14-16

Section of Nephrology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Department of Pharmacology, Baylor College of Medicine, Houston, Texas, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2017.03.024DOI Listing
July 2017

Paraprotein-Related Kidney Disease: Kidney Injury from Paraproteins-What Determines the Site of Injury?

Clin J Am Soc Nephrol 2016 12 15;11(12):2288-2294. Epub 2016 Aug 15.

Department of Medicine, Nephrology Research and Training Center and

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http://dx.doi.org/10.2215/CJN.02560316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142058PMC
December 2016

Dynamin-Related Protein 1 Deficiency Improves Mitochondrial Fitness and Protects against Progression of Diabetic Nephropathy.

J Am Soc Nephrol 2016 09 29;27(9):2733-47. Epub 2016 Jan 29.

Section of Nephrology, Department of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas; Pharmacology, Baylor College of Medicine, Houston, Texas; and

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http://dx.doi.org/10.1681/ASN.2015101096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004662PMC
September 2016

miR-93 regulates Msk2-mediated chromatin remodelling in diabetic nephropathy.

Nat Commun 2016 06 28;7:12076. Epub 2016 Jun 28.

Section of Nephrology, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1468, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/ncomms12076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931323PMC
June 2016

Paradoxical Role of IL-17 in Progression of Diabetic Nephropathy.

J Am Soc Nephrol 2016 Mar 2;27(3):657-8. Epub 2015 Sep 2.

Section of Nephrology, The University of Texas MD Anderson Cancer Center, Houston, Texas; and Department of Pharmacology, Baylor College of Medicine, Houston, Texas

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http://dx.doi.org/10.1681/ASN.2015070813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769213PMC
March 2016

Diabetic Nephropathy: Emerging Biomarkers for Risk Assessment.

Diabetes 2015 Sep;64(9):3063-5

Section of Nephrology, The University of Texas MD Anderson Cancer Center, Houston, TX Department of Pharmacology, Baylor College of Medicine, Houston, TX

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http://dx.doi.org/10.2337/db15-0738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876692PMC
September 2015

FSP-1 Impairs the Function of Endothelium Leading to Failure of Arteriovenous Grafts in Diabetic Mice.

Endocrinology 2015 Jun 16;156(6):2200-10. Epub 2015 Mar 16.

Nephrology Division (J.L., M.L., W.E.M., M.Y., J.C.), Baylor College of Medicine, Houston, Texas 77030; Emergency Medicine (F.R.D.), University of Texas MD Anderson Cancer Center, Houston, Texas 77030; and Department of Emergency (J.L.), Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China 430074.

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http://dx.doi.org/10.1210/en.2014-1841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430603PMC
June 2015

MicroRNAs and their applications in kidney diseases.

Pediatr Nephrol 2015 May 14;30(5):727-40. Epub 2014 Jun 14.

Section of Nephrology, The University of Texas at MD Anderson Cancer Center, 1400 Pressler Street, Unit 1468, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1007/s00467-014-2867-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265577PMC
May 2015

New insights into molecular mechanisms of diabetic kidney disease.

Am J Kidney Dis 2014 Feb;63(2 Suppl 2):S63-83

Interdepartmental Graduate Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, TX; Section of Nephrology, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX. Electronic address:

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http://dx.doi.org/10.1053/j.ajkd.2013.10.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932114PMC
February 2014

MicroRNA-22 is a master regulator of bone morphogenetic protein-7/6 homeostasis in the kidney.

J Biol Chem 2013 Dec 25;288(51):36202-14. Epub 2013 Oct 25.

From the Nephrology Section, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030.

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http://dx.doi.org/10.1074/jbc.M113.498634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868735PMC
December 2013

Strategies to reverse endothelial dysfunction in diabetic nephropathy.

Kidney Int 2012 Dec;82(11):1151-4

Division of Nephrology, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/ki.2012.306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914716PMC
December 2012

Managing microvascular complications of diabetes with microRNAs.

J Am Soc Nephrol 2012 Feb 12;23(2):185-7. Epub 2012 Jan 12.

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http://dx.doi.org/10.1681/ASN.2011121222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269171PMC
February 2012

Injectable multidomain peptide nanofiber hydrogel as a delivery agent for stem cell secretome.

Biomacromolecules 2011 May 13;12(5):1651-7. Epub 2011 Apr 13.

Department of Chemistry, Rice University, Houston, Texas 77005, United States.

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http://dx.doi.org/10.1021/bm200035rDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150749PMC
May 2011

MicroRNA-29c is a signature microRNA under high glucose conditions that targets Sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy.

J Biol Chem 2011 Apr 10;286(13):11837-48. Epub 2011 Feb 10.

Division of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1074/jbc.M110.194969DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064234PMC
April 2011

Peptide nanofibers preconditioned with stem cell secretome are renoprotective.

J Am Soc Nephrol 2011 Apr 17;22(4):704-17. Epub 2011 Mar 17.

Department of Medicine/Nephrology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

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http://dx.doi.org/10.1681/ASN.2010040403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065226PMC
April 2011

Identification of microRNA-93 as a novel regulator of vascular endothelial growth factor in hyperglycemic conditions.

J Biol Chem 2010 Jul 25;285(30):23457-65. Epub 2010 May 25.

Division of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M110.136168
Publisher Site
http://dx.doi.org/10.1074/jbc.M110.136168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906336PMC
July 2010

Rap1b GTPase ameliorates glucose-induced mitochondrial dysfunction.

J Am Soc Nephrol 2008 Dec 27;19(12):2293-301. Epub 2008 Aug 27.

Department of Pathology, Northwestern University, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1681/ASN.2008030336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588105PMC
December 2008

Targeting of RhoA/ROCK signaling ameliorates progression of diabetic nephropathy independent of glucose control.

Diabetes 2008 Mar 14;57(3):714-23. Epub 2007 Dec 14.

Department of Medicine, Feinberg School of Medicine, Northwestern University, Houston, Texas, USA.

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http://dx.doi.org/10.2337/db07-1241DOI Listing
March 2008

Diabetic nephropathy: mechanisms of renal disease progression.

Exp Biol Med (Maywood) 2008 Jan;233(1):4-11

Department of Pathology, Northwestern University School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.3181/0705-MR-134DOI Listing
January 2008

Chimerism of the renal glomerulus revisited.

J Am Soc Nephrol 2007 Aug 11;18(8):2215-7. Epub 2007 Jul 11.

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http://www.jasn.org/cgi/doi/10.1681/ASN.2007060689
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http://dx.doi.org/10.1681/ASN.2007060689DOI Listing
August 2007

Contribution of proteoglycans towards the integrated functions of renal glomerular capillaries: a historical perspective.

Am J Pathol 2007 Jul;171(1):9-13

Northwestern University Medical School, Department of Pathology, Chicago, IL 60611, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1941605PMC
http://dx.doi.org/10.2353/ajpath.2007.070356DOI Listing
July 2007

Expression and functional characteristics of tubular transporters: P-glycoprotein, PEPT1, and PEPT2 in renal mass reduction and diabetes.

Am J Physiol Renal Physiol 2006 Nov;291(5):F972-80

Dept. of Pathology, Northwestern Univ. Medical School, 303 E. Chicago Ave, Chicago, IL, USA.

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http://dx.doi.org/10.1152/ajprenal.00110.2006DOI Listing
November 2006

RhoA-mediated, tumor necrosis factor alpha-induced activation of NF-kappaB in rheumatoid synoviocytes: inhibitory effect of simvastatin.

Arthritis Rheum 2006 Nov;54(11):3441-51

Department of Rheumatology, First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan Road 2, Guangzhou, Guangdong 510080, Peoples Republic of China.

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http://dx.doi.org/10.1002/art.22169DOI Listing
November 2006

Cell biology of diabetic kidney disease.

Nephron Exp Nephrol 2005 8;101(3):e100-10. Epub 2005 Aug 8.

Department of Pathology, Northwestern University School of Medicine, Chicago, Ill 60611, USA.

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https://www.karger.com/Article/FullText/87339
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http://dx.doi.org/10.1159/000087339DOI Listing
April 2006

Modulation of renal-specific oxidoreductase/myo-inositol oxygenase by high-glucose ambience.

Proc Natl Acad Sci U S A 2005 Dec 5;102(50):17952-7. Epub 2005 Dec 5.

Department of Pathology, Northwestern University Medical School, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1073/pnas.0509089102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1312416PMC
December 2005

HMG CoA reductase inhibition modulates VEGF-induced endothelial cell hyperpermeability by preventing RhoA activation and myosin regulatory light chain phosphorylation.

FASEB J 2005 Nov 13;19(13):1845-7. Epub 2005 Sep 13.

Division of Nephrology/Hypertension, Feinberg School of Medicine, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1096/fj.05-4240fjeDOI Listing
November 2005

Renal-specific oxidoreductase biphasic expression under high glucose ambience during fetal versus neonatal development.

Kidney Int 2005 Oct;68(4):1670-83

Department of Pathology, Northwestern University Medical Center, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1111/j.1523-1755.2005.00611.xDOI Listing
October 2005

Angiotensin II stimulates alpha3(IV) collagen production in mouse podocytes via TGF-beta and VEGF signalling: implications for diabetic glomerulopathy.

Nephrol Dial Transplant 2005 Jul 19;20(7):1320-8. Epub 2005 Apr 19.

Renal-Electrolyte and Hypertension Division of the University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1093/ndt/gfh837DOI Listing
July 2005

Hyperglycemia: its imminent effects on mammalian nephrogenesis.

Pediatr Nephrol 2005 Jul 5;20(7):858-66. Epub 2005 May 5.

Department of Pathology, Northwestern University Medical School, Chicago, IL, USA.

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http://dx.doi.org/10.1007/s00467-005-1888-7DOI Listing
July 2005

Effects of statin therapy on the progression of chronic kidney disease.

Adv Chronic Kidney Dis 2005 Apr;12(2):187-95

Division of Nephrology/Hypertension, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1053/j.ackd.2005.01.007DOI Listing
April 2005

Simvastatin modulates angiotensin II signaling pathway by preventing Rac1-mediated upregulation of p27.

J Am Soc Nephrol 2004 Jul;15(7):1711-20

Division of Nephrology/Hypertension, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1097/01.asn.0000129839.91567.68DOI Listing
July 2004

Modulatory effects of HMG-CoA reductase inhibitors in diabetic microangiopathy.

FASEB J 2004 May;18(7):805-15

Division of Nephrology/Hypertension, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA .

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http://dx.doi.org/10.1096/fj.03-0839revDOI Listing
May 2004

Immunomodulatory effects of HMG-CoA reductase inhibitors.

Arch Immunol Ther Exp (Warsz) 2003 ;51(3):139-48

Department of Medicine, The Feinberg School of Medicine of Northwestern University, Chicago, IL 60611, USA.

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March 2004

Update of extracellular matrix, its receptors, and cell adhesion molecules in mammalian nephrogenesis.

Am J Physiol Renal Physiol 2004 Feb;286(2):F202-15

Department of Pathology, Northwestern Univ. Medical School, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1152/ajprenal.00157.2003DOI Listing
February 2004

Gene regulation of aldose-, aldehyde- and a renal specific oxido reductase (RSOR) in the pathobiology of diabetes mellitus.

Curr Med Chem 2003 Aug;10(15):1399-406

Departments of Pathology & Medicine, Northwestern University Medical School, Chicago, Illinois, USA.

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http://dx.doi.org/10.2174/0929867033457368DOI Listing
August 2003

Epigenetic and genetic analysis of p16 in dermal fibroblasts from type 1 diabetic patients with nephropathy.

Kidney Int 2003 Jun;63(6):2094-102

Department of Medicine, Division of Nephrology/Hypertension, The Feinberg School of Medicine of Northwestern University, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1046/j.1523-1755.2003.00013.xDOI Listing
June 2003

High glucose stimulates synthesis of fibronectin via a novel protein kinase C, Rap1b, and B-Raf signaling pathway.

J Biol Chem 2002 Nov 23;277(44):41725-35. Epub 2002 Aug 23.

Department of Pathology, Northwestern University Medical School, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1074/jbc.M203957200DOI Listing
November 2002

Isolation and functional analysis of mouse UbA52 gene and its relevance to diabetic nephropathy.

J Biol Chem 2002 Aug 24;277(33):29953-62. Epub 2002 May 24.

Department of Pathology, Northwestern University Medical School, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1074/jbc.M204665200DOI Listing
August 2002

Lupus membranous glomerulonephritis mimicking hepatitis C-associated nephropathy.

Am J Kidney Dis 2002 Mar;39(3):E19

Division of Nephrology/Hypertension, Northwestern University Medical School, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1053/ajkd.2002.31430DOI Listing
March 2002