Publications

CCT complex restricts neuropathogenic protein aggregation via autophagy.
Nat Commun 2016 Dec 8;7:13821. Epub 2016 Dec 8.
Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2XY, UK.

Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy.
Nat Commun 2015 Aug 20;6:8045. Epub 2015 Aug 20.
Department of Medical Genetics, Cambridge Institute for Medical Research, Wellcome/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0XY, UK.

PICALM modulates autophagy activity and tau accumulation.
Nat Commun 2014 Sep 22;5:4998. Epub 2014 Sep 22.
Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK.

IGF-1 receptor antagonism inhibits autophagy.
Hum Mol Genet 2013 Nov 25;22(22):4528-44. Epub 2013 Jun 25.
Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Wellcome/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0XY, UK.

Lysosomal positioning coordinates cellular nutrient responses.
Nat Cell Biol 2011 Apr 13;13(4):453-60. Epub 2011 Mar 13.
Department of Medical Genetics, Cambridge Institute for Medical Genetics, Wellcome Trust/MRC Building, Hills Road, Cambridge, CB2 0XY, UK.


Novel targets for Huntington's disease in an mTOR-independent autophagy pathway.
Nat Chem Biol 2008 May;4(5):295-305
Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0XY, UK.

OF