Falk W Lohoff

Falk W Lohoff

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Falk W Lohoff

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Deletion of the vesicular monoamine transporter 1 (vmat1/slc18a1) gene affects dopamine signaling.

Brain Res 2019 Jun 24;1712:151-157. Epub 2019 Jan 24.

Department of Pharmacology, Uniformed Services University, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.brainres.2019.01.029DOI Listing
June 2019

PCSK9 is Increased in Cerebrospinal Fluid of Individuals With Alcohol Use Disorder.

Alcohol Clin Exp Res 2019 Jun 3;43(6):1163-1169. Epub 2019 May 3.

Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1111/acer.14039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696932PMC
June 2019

Association of High-Intensity Binge Drinking With Lipid and Liver Function Enzyme Levels.

JAMA Netw Open 2019 Jun 5;2(6):e195844. Epub 2019 Jun 5.

Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1001/jamanetworkopen.2019.5844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6575145PMC
June 2019

Lack of Association Between Serotonin Transporter Gene (SLC6A4) Promoter Methylation and Amygdala Response During Negative Emotion Processing in Individuals With Alcohol Dependence.

Alcohol Alcohol 2019 May;54(3):209-215

Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 10 Center Drive (10CRC), Bethesda, MD, USA.

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http://dx.doi.org/10.1093/alcalc/agz032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516430PMC
May 2019

Lipid-Lowering Drug Effects Beyond the Cardiovascular System: Relevance for Neuropsychiatric Disorders.

Authors:
Falk W Lohoff

Int J Neuropsychopharmacol 2018 12;21(12):1076-1078

Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD.

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https://academic.oup.com/ijnp/advance-article/doi/10.1093/ij
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http://dx.doi.org/10.1093/ijnp/pyy087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276049PMC
December 2018

Imaging resilience and recovery in alcohol dependence.

Addiction 2018 Oct 4;113(10):1933-1950. Epub 2018 Jun 4.

Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charité-Universitätsmedizin, Berlin, Germany.

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http://dx.doi.org/10.1111/add.14259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128779PMC
October 2018

DNA methylation age is accelerated in alcohol dependence.

Transl Psychiatry 2018 09 5;8(1):182. Epub 2018 Sep 5.

Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.

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http://www.nature.com/articles/s41398-018-0233-4
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http://dx.doi.org/10.1038/s41398-018-0233-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125381PMC
September 2018

Association Analysis Between Genetic Variation in GATA Binding Protein 4 (GATA4) and Alcohol Use Disorder.

Alcohol Alcohol 2018 Jul;53(4):361-367

Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 10 Center Drive (10CRC), Bethesda, MD, USA.

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http://dx.doi.org/10.1093/alcalc/agx120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016699PMC
July 2018

The major depressive disorder GWAS-supported variant rs10514299 in TMEM161B-MEF2C predicts putamen activation during reward processing in alcohol dependence.

Transl Psychiatry 2018 07 13;8(1):131. Epub 2018 Jul 13.

Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/s41398-018-0184-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045574PMC
July 2018

Random forest based classification of alcohol dependence patients and healthy controls using resting state MRI.

Neurosci Lett 2018 05 4;676:27-33. Epub 2018 Apr 4.

Clinical NeuroImaging Research Core, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, United States. Electronic address:

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http://dx.doi.org/10.1016/j.neulet.2018.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960433PMC
May 2018

Dopamine Transporter Gene Methylation is Associated with Nucleus Accumbens Activation During Reward Processing in Healthy but not Alcohol-Dependent Individuals.

Alcohol Clin Exp Res 2018 Jan 27;42(1):21-31. Epub 2017 Nov 27.

Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1111/acer.13526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010188PMC
January 2018

Genome-wide association study of treatment response to venlafaxine XR in generalized anxiety disorder.

Psychiatry Res 2017 08 14;254:8-11. Epub 2017 Apr 14.

Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, United States; Department of Psychiatry, Mood and Anxiety Disorders Treatment and Research Program, University of Pennsylvania, Philadelphia, PA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2017.04.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798606PMC
August 2017

Overview of the Genetics of Alcohol Use Disorder.

Alcohol Alcohol 2016 Sep 21;51(5):507-14. Epub 2016 Jul 21.

Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA

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http://alcalc.oxfordjournals.org/content/alcalc/early/2016/0
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http://dx.doi.org/10.1093/alcalc/agw046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004749PMC
September 2016

Genetic Variation in the Vesicular Monoamine Transporter 1 (VMAT1/SLC18A1) Gene and Alcohol Withdrawal Severity.

Alcohol Clin Exp Res 2016 Mar 15;40(3):474-81. Epub 2016 Feb 15.

Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1111/acer.12991DOI Listing
March 2016

Serotonin pathway polymorphisms and the treatment of major depressive disorder and anxiety disorders.

Pharmacogenomics 2015 ;16(5):541-53

Section on Clinical Genomics & Experimental Therapeutics (CGET), Laboratory of Clinical & Translational Studies (LCTS), National Institute on Alcohol Abuse & Alcoholism (NIAAA), NIH, Bethesda, MD 20892-1540, USA.

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http://dx.doi.org/10.2217/pgs.15.15DOI Listing
January 2016

Resting-state functional connectivity and presynaptic monoamine signaling in Alcohol Dependence.

Hum Brain Mapp 2015 Dec 14;36(12):4808-18. Epub 2015 Sep 14.

Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1002/hbm.22951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715530PMC
December 2015

Pharmacogenetics of alcohol use disorders and comorbid psychiatric disorders.

Psychiatry Res 2015 Dec 14;230(2):121-9. Epub 2015 Sep 14.

Laboratory of Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2015.09.019DOI Listing
December 2015

Lack of influence of DAT1 and DRD2 gene variants on antidepressant response in generalized anxiety disorder.

Hum Psychopharmacol 2014 Jul 10;29(4):316-21. Epub 2014 Apr 10.

Psychiatric Pharmacogenetics Laboratory, Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1002/hup.2404DOI Listing
July 2014

Identification of CHRNA5 rare variants in African-American heavy smokers.

Psychiatr Genet 2014 Jun;24(3):102-9

Department of Psychiatry, Perelman School of Medicine, Center for Neurobiology and Behavior, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1097/YPG.0000000000000029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015337PMC
June 2014

Remission of generalized anxiety disorder after 6 months of open-label treatment with venlafaxine XR.

Psychother Psychosom 2013 20;82(6):363-71. Epub 2013 Sep 20.

Mood and Anxiety Disorders Section, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, Pa., USA.

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http://dx.doi.org/10.1159/000351410DOI Listing
April 2014

Individual differences in the morphometry and activation of time perception networks are influenced by dopamine genotype.

Neuroimage 2014 Apr 19;89:10-22. Epub 2013 Nov 19.

Dept. of Neurology, University of Pennsylvania, USA; Center for Cognitive Neuroscience, University of Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.neuroimage.2013.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932560PMC
April 2014

The dopamine receptor D2 (DRD2) SNP rs1076560 is associated with opioid addiction.

Ann Hum Genet 2014 Jan 25;78(1):33-9. Epub 2013 Nov 25.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, 19104, USA.

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http://doi.wiley.com/10.1111/ahg.12046
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http://dx.doi.org/10.1111/ahg.12046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013426PMC
January 2014

Genetic polymorphisms in the PACAP and PAC1 receptor genes and treatment response to venlafaxine XR in generalized anxiety disorder.

Psychiatry Res 2013 Dec 22;210(3):1299-300. Epub 2013 Aug 22.

Psychiatric Pharmacogenetics Laboratory, Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, United States.

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http://dx.doi.org/10.1016/j.psychres.2013.07.038DOI Listing
December 2013

An intronic variant in OPRD1 predicts treatment outcome for opioid dependence in African-Americans.

Neuropsychopharmacology 2013 Sep 23;38(10):2003-10. Epub 2013 Apr 23.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1038/npp.2013.99DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746708PMC
September 2013

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.

Authors:
S Hong Lee Stephan Ripke Benjamin M Neale Stephen V Faraone Shaun M Purcell Roy H Perlis Bryan J Mowry Anita Thapar Michael E Goddard John S Witte Devin Absher Ingrid Agartz Huda Akil Farooq Amin Ole A Andreassen Adebayo Anjorin Richard Anney Verneri Anttila Dan E Arking Philip Asherson Maria H Azevedo Lena Backlund Judith A Badner Anthony J Bailey Tobias Banaschewski Jack D Barchas Michael R Barnes Thomas B Barrett Nicholas Bass Agatino Battaglia Michael Bauer Mònica Bayés Frank Bellivier Sarah E Bergen Wade Berrettini Catalina Betancur Thomas Bettecken Joseph Biederman Elisabeth B Binder Donald W Black Douglas H R Blackwood Cinnamon S Bloss Michael Boehnke Dorret I Boomsma Gerome Breen René Breuer Richard Bruggeman Paul Cormican Nancy G Buccola Jan K Buitelaar William E Bunney Joseph D Buxbaum William F Byerley Enda M Byrne Sian Caesar Wiepke Cahn Rita M Cantor Miguel Casas Aravinda Chakravarti Kimberly Chambert Khalid Choudhury Sven Cichon C Robert Cloninger David A Collier Edwin H Cook Hilary Coon Bru Cormand Aiden Corvin William H Coryell David W Craig Ian W Craig Jennifer Crosbie Michael L Cuccaro David Curtis Darina Czamara Susmita Datta Geraldine Dawson Richard Day Eco J De Geus Franziska Degenhardt Srdjan Djurovic Gary J Donohoe Alysa E Doyle Jubao Duan Frank Dudbridge Eftichia Duketis Richard P Ebstein Howard J Edenberg Josephine Elia Sean Ennis Bruno Etain Ayman Fanous Anne E Farmer I Nicol Ferrier Matthew Flickinger Eric Fombonne Tatiana Foroud Josef Frank Barbara Franke Christine Fraser Robert Freedman Nelson B Freimer Christine M Freitag Marion Friedl Louise Frisén Louise Gallagher Pablo V Gejman Lyudmila Georgieva Elliot S Gershon Daniel H Geschwind Ina Giegling Michael Gill Scott D Gordon Katherine Gordon-Smith Elaine K Green Tiffany A Greenwood Dorothy E Grice Magdalena Gross Detelina Grozeva Weihua Guan Hugh Gurling Lieuwe De Haan Jonathan L Haines Hakon Hakonarson Joachim Hallmayer Steven P Hamilton Marian L Hamshere Thomas F Hansen Annette M Hartmann Martin Hautzinger Andrew C Heath Anjali K Henders Stefan Herms Ian B Hickie Maria Hipolito Susanne Hoefels Peter A Holmans Florian Holsboer Witte J Hoogendijk Jouke-Jan Hottenga Christina M Hultman Vanessa Hus Andrés Ingason Marcus Ising Stéphane Jamain Edward G Jones Ian Jones Lisa Jones Jung-Ying Tzeng Anna K Kähler René S Kahn Radhika Kandaswamy Matthew C Keller James L Kennedy Elaine Kenny Lindsey Kent Yunjung Kim George K Kirov Sabine M Klauck Lambertus Klei James A Knowles Martin A Kohli Daniel L Koller Bettina Konte Ania Korszun Lydia Krabbendam Robert Krasucki Jonna Kuntsi Phoenix Kwan Mikael Landén Niklas Långström Mark Lathrop Jacob Lawrence William B Lawson Marion Leboyer David H Ledbetter Phil H Lee Todd Lencz Klaus-Peter Lesch Douglas F Levinson Cathryn M Lewis Jun Li Paul Lichtenstein Jeffrey A Lieberman Dan-Yu Lin Don H Linszen Chunyu Liu Falk W Lohoff Sandra K Loo Catherine Lord Jennifer K Lowe Susanne Lucae Donald J MacIntyre Pamela A F Madden Elena Maestrini Patrik K E Magnusson Pamela B Mahon Wolfgang Maier Anil K Malhotra Shrikant M Mane Christa L Martin Nicholas G Martin Manuel Mattheisen Keith Matthews Morten Mattingsdal Steven A McCarroll Kevin A McGhee James J McGough Patrick J McGrath Peter McGuffin Melvin G McInnis Andrew McIntosh Rebecca McKinney Alan W McLean Francis J McMahon William M McMahon Andrew McQuillin Helena Medeiros Sarah E Medland Sandra Meier Ingrid Melle Fan Meng Jobst Meyer Christel M Middeldorp Lefkos Middleton Vihra Milanova Ana Miranda Anthony P Monaco Grant W Montgomery Jennifer L Moran Daniel Moreno-De-Luca Gunnar Morken Derek W Morris Eric M Morrow Valentina Moskvina Pierandrea Muglia Thomas W Mühleisen Walter J Muir Bertram Müller-Myhsok Michael Murtha Richard M Myers Inez Myin-Germeys Michael C Neale Stan F Nelson Caroline M Nievergelt Ivan Nikolov Vishwajit Nimgaonkar Willem A Nolen Markus M Nöthen John I Nurnberger Evaristus A Nwulia Dale R Nyholt Colm O'Dushlaine Robert D Oades Ann Olincy Guiomar Oliveira Line Olsen Roel A Ophoff Urban Osby Michael J Owen Aarno Palotie Jeremy R Parr Andrew D Paterson Carlos N Pato Michele T Pato Brenda W Penninx Michele L Pergadia Margaret A Pericak-Vance Benjamin S Pickard Jonathan Pimm Joseph Piven Danielle Posthuma James B Potash Fritz Poustka Peter Propping Vinay Puri Digby J Quested Emma M Quinn Josep Antoni Ramos-Quiroga Henrik B Rasmussen Soumya Raychaudhuri Karola Rehnström Andreas Reif Marta Ribasés John P Rice Marcella Rietschel Kathryn Roeder Herbert Roeyers Lizzy Rossin Aribert Rothenberger Guy Rouleau Douglas Ruderfer Dan Rujescu Alan R Sanders Stephan J Sanders Susan L Santangelo Joseph A Sergeant Russell Schachar Martin Schalling Alan F Schatzberg William A Scheftner Gerard D Schellenberg Stephen W Scherer Nicholas J Schork Thomas G Schulze Johannes Schumacher Markus Schwarz Edward Scolnick Laura J Scott Jianxin Shi Paul D Shilling Stanley I Shyn Jeremy M Silverman Susan L Slager Susan L Smalley Johannes H Smit Erin N Smith Edmund J S Sonuga-Barke David St Clair Matthew State Michael Steffens Hans-Christoph Steinhausen John S Strauss Jana Strohmaier T Scott Stroup James S Sutcliffe Peter Szatmari Szabocls Szelinger Srinivasa Thirumalai Robert C Thompson Alexandre A Todorov Federica Tozzi Jens Treutlein Manfred Uhr Edwin J C G van den Oord Gerard Van Grootheest Jim Van Os Astrid M Vicente Veronica J Vieland John B Vincent Peter M Visscher Christopher A Walsh Thomas H Wassink Stanley J Watson Myrna M Weissman Thomas Werge Thomas F Wienker Ellen M Wijsman Gonneke Willemsen Nigel Williams A Jeremy Willsey Stephanie H Witt Wei Xu Allan H Young Timothy W Yu Stanley Zammit Peter P Zandi Peng Zhang Frans G Zitman Sebastian Zöllner Bernie Devlin John R Kelsoe Pamela Sklar Mark J Daly Michael C O'Donovan Nicholas Craddock Patrick F Sullivan Jordan W Smoller Kenneth S Kendler Naomi R Wray

Nat Genet 2013 Sep 11;45(9):984-94. Epub 2013 Aug 11.

The University of Queensland, Queensland Brain Institute, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1038/ng.2711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800159PMC
September 2013

Further evidence for association of polymorphisms in the CNR1 gene with cocaine addiction: confirmation in an independent sample and meta-analysis.

Addict Biol 2013 Jul 25;18(4):702-8. Epub 2011 Jul 25.

Psychiatric Pharmacogenetics Laboratory Center for Neurobiology and Behavior Treatment Research Center Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1111/j.1369-1600.2011.00346.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223560PMC
July 2013

COMT and ANKK1-Taq-Ia genetic polymorphisms influence visual working memory.

PLoS One 2013 31;8(1):e55862. Epub 2013 Jan 31.

Memory and Brain Laboratory, Department of Psychology, University of Nevada, Reno, Nevada, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055862PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561341PMC
July 2013

Case-control association study of WLS variants in opioid and cocaine addicted populations.

Psychiatry Res 2013 Jun 5;208(1):62-6. Epub 2013 Apr 5.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.psychres.2013.03.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665700PMC
June 2013

Low frequency genetic variants in the μ-opioid receptor (OPRM1) affect risk for addiction to heroin and cocaine.

Neurosci Lett 2013 May 20;542:71-5. Epub 2013 Feb 20.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.neulet.2013.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640707PMC
May 2013

Association analysis between the A118G polymorphism in the OPRM1 gene and treatment response to venlafaxine XR in generalized anxiety disorder.

Hum Psychopharmacol 2013 May 8;28(3):258-62. Epub 2013 May 8.

Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1002/hup.2317DOI Listing
May 2013

Neuronal calcium sensor-1 and cocaine addiction: a genetic association study in African-Americans and European Americans.

Neurosci Lett 2012 Nov 20;531(1):46-51. Epub 2012 Sep 20.

Psychiatric Pharmacogenetics Laboratory, Center for Neurobiology and Behavior, Department of Psychiatry, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.neulet.2012.09.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895491PMC
November 2012

Evidence for the use of vilazodone in the treatment of major depressive disorder.

Expert Opin Pharmacother 2012 Oct 13;13(15):2215-24. Epub 2012 Sep 13.

University of the Sciences, Philadelphia College of Pharmacy, Department of Pharmacy Practice, Administration, PA, USA.

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http://www.tandfonline.com/doi/full/10.1517/14656566.2012.72
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http://dx.doi.org/10.1517/14656566.2012.721776DOI Listing
October 2012

Variation in the catechol-O-methyltransferase (COMT) gene and treatment response to venlafaxine XR in generalized anxiety disorder.

Psychiatry Res 2012 Jun 13;198(1):112-5. Epub 2012 Mar 13.

Psychiatric Pharmacogenetics Laboratory, Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.psychres.2011.12.034DOI Listing
June 2012

Association study of the β-arrestin 2 gene (ARRB2) with opioid and cocaine dependence in a European-American population.

Psychiatr Genet 2012 Jun;22(3):141-5

Translational Research Laboratory, Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania, 125 S. 31st St, School of Medicine, Rm. 2109, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1097/YPG.0b013e3283539528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920286PMC
June 2012

Pharmacogenetics of antidepressant drugs: current clinical practice and future directions.

Pharmacogenomics 2012 Mar;13(4):441-64

University of Pennsylvania School of Medicine, Department of Psychiatry, Center for Neurobiology & Behavior, Translational Research Laboratories, 125 South 31st Street, Room 2213, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.2217/pgs.12.1DOI Listing
March 2012

Pharmacological treatment of generalized anxiety disorder.

Expert Opin Pharmacother 2011 Nov 28;12(16):2457-67. Epub 2011 Sep 28.

University of the Sciences, Philadelphia College of Pharmacy, Department of Pharmacy Practice/Pharmacy Administration, PA, USA.

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http://www.tandfonline.com/doi/full/10.1517/14656566.2011.61
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http://dx.doi.org/10.1517/14656566.2011.618496DOI Listing
November 2011

Double dissociation of dopamine genes and timing in humans.

J Cogn Neurosci 2011 Oct 24;23(10):2811-21. Epub 2011 Jan 24.

University of Pennsylvania, Philadelphia, PA 19104-6241, USA.

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http://dx.doi.org/10.1162/jocn.2011.21626DOI Listing
October 2011

Association analysis between the 5-HTTLPR polymorphism in the SLC6A4 gene and generalized anxiety disorder.

Psychiatr Genet 2011 Oct;21(5):267-8

Departments of Psychiatry, Psychiatric Pharmacogenetics Laboratory, University of Pennsylvania, Philadelphia, USA.

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https://insights.ovid.com/crossref?an=00041444-201110000-000
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http://dx.doi.org/10.1097/YPG.0b013e3283457b51DOI Listing
October 2011

Association analysis between the Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) gene and treatment response to venlafaxine XR in generalized anxiety disorder.

Neurosci Lett 2011 Oct 26;503(3):200-2. Epub 2011 Aug 26.

Psychiatric Pharmacogenetics Laboratory, Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, United States.

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http://dx.doi.org/10.1016/j.neulet.2011.08.035DOI Listing
October 2011

The future of psychiatric pharmacogenomics.

Authors:
Falk W Lohoff

Pharmacogenomics 2011 Jul;12(7):927-9

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http://dx.doi.org/10.2217/pgs.11.60DOI Listing
July 2011

Dopamine transporter genotype modulation of neural responses to smoking cues: confirmation in a new cohort.

Addict Biol 2011 Apr 8;16(2):308-22. Epub 2011 Feb 8.

Research Assistant Professor of Neuroscience, Addiction Treatment Research Center, Department of Psychiatry, University of Pennsylvania School of Medicine, 3900 Chestnut Street, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1111/j.1369-1600.2010.00277.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348624PMC
April 2011

Association analysis between polymorphisms in the myo-inositol monophosphatase 2 (IMPA2) gene and bipolar disorder.

Prog Neuropsychopharmacol Biol Psychiatry 2010 Dec 26;34(8):1515-9. Epub 2010 Aug 26.

Psychiatric Pharmacogenetics Laboratory, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.pnpbp.2010.08.015DOI Listing
December 2010

Overview of the genetics of major depressive disorder.

Authors:
Falk W Lohoff

Curr Psychiatry Rep 2010 Dec;12(6):539-46

Department of Psychiatry, University of Pennsylvania School of Medicine, Center for Neurobiology and Behavior, Philadelphia, 19104, USA.

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http://dx.doi.org/10.1007/s11920-010-0150-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077049PMC
December 2010

Time to relapse after 6 and 12 months' treatment of generalized anxiety disorder with venlafaxine extended release.

Arch Gen Psychiatry 2010 Dec;67(12):1274-81

Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA.

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http://dx.doi.org/10.1001/archgenpsychiatry.2010.170DOI Listing
December 2010

Genetic variants in the vesicular monoamine transporter 1 (VMAT1/SLC18A1) and neuropsychiatric disorders.

Authors:
Falk W Lohoff

Methods Mol Biol 2010 ;637:165-80

Translational Research Laboratories, Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/978-1-60761-700-6_9DOI Listing
July 2010

Association between polymorphisms in the metallophosphoesterase (MPPE1) gene and bipolar disorder.

Am J Med Genet B Neuropsychiatr Genet 2010 Apr;153B(3):830-6

Translational Research Laboratory, Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania School of Medicine, 125 South 31st Street, Room 2213, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1002/ajmg.b.31042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029019PMC
April 2010

Association analysis between polymorphisms in the dopamine D2 receptor (DRD2) and dopamine transporter (DAT1) genes with cocaine dependence.

Neurosci Lett 2010 Apr 17;473(2):87-91. Epub 2010 Feb 17.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S030439401000179
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http://dx.doi.org/10.1016/j.neulet.2010.02.021DOI Listing
April 2010

Ziprasidone treatment of refractory generalized anxiety disorder: a placebo-controlled, double-blind study.

J Clin Psychopharmacol 2010 Apr;30(2):185-9

Mood and Anxiety Disorders Section, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1097/JCP.0b013e3181d21951DOI Listing
April 2010

Pharmacogenetic considerations in the treatment of psychiatric disorders.

Expert Opin Pharmacother 2010 Feb;11(3):423-39

University of Pennsylvania School of Medicine, Center for Neurobiology and Behavior, Department of Psychiatry, Translational Research Laboratories, 125 South 31st Street, Room 2213, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1517/14656560903508762DOI Listing
February 2010

Association analysis between polymorphisms in the conserved dopamine neurotrophic factor (CDNF) gene and cocaine dependence.

Neurosci Lett 2009 Apr 21;453(3):199-203. Epub 2009 Feb 21.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.neulet.2009.02.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680755PMC
April 2009

DAT genotype modulates brain and behavioral responses elicited by cigarette cues.

Neuropsychopharmacology 2009 Feb 13;34(3):717-28. Epub 2008 Aug 13.

Department of Psychiatry, Addiction Treatment Research Center, University of Pennsylvania and Philadelphia VA Medical Center, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1038/npp.2008.124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348625PMC
February 2009

Association between the catechol-O-methyltransferase Val158Met polymorphism and cocaine dependence.

Neuropsychopharmacology 2008 Dec 13;33(13):3078-84. Epub 2008 Aug 13.

Department of Psychiatry, Translational Research Laboratories, Center for Neurobiology and Behavior, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1038/npp.2008.126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583214PMC
December 2008

Fine mapping of a major QTL influencing morphine preference in C57BL/6 and DBA/2 mice using congenic strains.

Neuropsychopharmacology 2008 Nov 20;33(12):2801-9. Epub 2008 Feb 20.

Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1038/npp.2008.14DOI Listing
November 2008

Association between polymorphisms in the vesicular monoamine transporter 1 gene (VMAT1/SLC18A1) on chromosome 8p and schizophrenia.

Neuropsychobiology 2008 2;57(1-2):55-60. Epub 2008 May 2.

Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA.

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https://www.karger.com/Article/FullText/129668
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http://dx.doi.org/10.1159/000129668DOI Listing
September 2008

Association between polymorphisms in the vesicle-associated membrane protein-associated protein A (VAPA) gene on chromosome 18p and bipolar disorder.

J Neural Transm (Vienna) 2008 Sep 30;115(9):1339-45. Epub 2008 Jul 30.

Department of Psychiatry, Translational Research Laboratories, University of Pennsylvania School of Medicine, Center for Neurobiology and Behavior, 125 South 31st Street, Room 2213, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1007/s00702-008-0093-9DOI Listing
September 2008

Genetic variants in the cocaine- and amphetamine-regulated transcript gene (CARTPT) and cocaine dependence.

Neurosci Lett 2008 Aug 24;440(3):280-3. Epub 2008 May 24.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.neulet.2008.05.073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2507865PMC
August 2008

Desvenlafaxine succinate for the treatment of major depressive disorder.

Expert Opin Pharmacother 2008 Aug;9(12):2129-36

University of Pennsylvania School of Medicine Mood and Anxiety Disorders Section, Department of Psychiatry, Center for Neurobiology and Behavior, Translational Research Laboratories, Philadelphia, PA 19104, USA.

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http://www.tandfonline.com/doi/full/10.1517/14656566.9.12.21
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http://dx.doi.org/10.1517/14656566.9.12.2129 DOI Listing
August 2008

Association analysis of the pituitary adenylate cyclase-activating polypeptide (PACAP/ADCYAP1) gene in bipolar disorder.

Psychiatr Genet 2008 Apr;18(2):53-8

Department of Psychiatry, Translational Research Laboratory, Center for Neurobiology and Behavior, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104 USA.

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http://dx.doi.org/10.1097/YPG.0b013e3282f60320DOI Listing
April 2008

Quantitative trait locus for seizure susceptibility on mouse chromosome 5 confirmed with reciprocal congenic strains.

Physiol Genomics 2007 Nov 14;31(3):458-62. Epub 2007 Aug 14.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104-3404, USA.

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http://dx.doi.org/10.1152/physiolgenomics.00123.2007DOI Listing
November 2007

Analysis of a quantitative trait locus for seizure susceptibility in mice using bacterial artificial chromosome-mediated gene transfer.

Epilepsia 2007 Sep 23;48(9):1667-1677. Epub 2007 May 23.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, PennsylvaniaResearch Service, Veteran's Affairs Medical Center, Coatesville, PennsylvaniaDepartment of Neurology, University of Cincinnati, Cincinnati, Ohio, U.S.A.

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http://dx.doi.org/10.1111/j.1528-1167.2007.01126.xDOI Listing
September 2007

Association of the met66 allele of brain-derived neurotrophic factor (BDNF) with smoking.

Psychopharmacology (Berl) 2007 Mar 21;190(4):433-9. Epub 2006 Dec 21.

Department of Psychiatry and Psychotherapy, University of Dresden, Fetscherstr 74, 01307, Dresden, Germany.

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http://link.springer.com/10.1007/s00213-006-0647-1
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http://dx.doi.org/10.1007/s00213-006-0647-1DOI Listing
March 2007

Variations in the vesicular monoamine transporter 1 gene (VMAT1/SLC18A1) are associated with bipolar i disorder.

Neuropsychopharmacology 2006 Dec 23;31(12):2739-47. Epub 2006 Aug 23.

Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1038/sj.npp.1301196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2507868PMC
December 2006

No association between polymorphisms in the prostate apoptosis factor-4 gene and cocaine dependence.

Psychiatr Genet 2006 Oct;16(5):193-6

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1097/01.ypg.0000218618.73257.8dDOI Listing
October 2006

Analysis of variations in the NAPG gene on chromosome 18p11 in bipolar disorder.

Psychiatr Genet 2006 Feb;16(1):3-8

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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February 2006

Lack of association between variations in the brain-derived neurotrophic factor (BDNF) gene and temporal lobe epilepsy.

Epilepsy Res 2005 Aug-Sep;66(1-3):59-62

Department of Psychiatry, Center for Neurobiology and Behaviour, University of Pennsylvania School of Medicine, 3535 Market Street, 2nd Floor, R2070, Philadelphia, PA 19104, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S092012110500135
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http://dx.doi.org/10.1016/j.eplepsyres.2005.06.005DOI Listing
January 2006

Lack of association between variations in the melanocortin 5 receptor gene and bipolar disorder.

Psychiatr Genet 2005 Dec;15(4):255-8

Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania School of Medicine, Philadelphia, 19104-6140, USA.

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December 2005

Association of a polymorphism in the Homer1 gene with cocaine dependence in an African American population.

Psychiatr Genet 2005 Dec;15(4):277-83

Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania School of Medicine, Clinical Research Building, Philadelphia, 19104, USA.

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December 2005

Confirmation of the association between a polymorphism in the promoter region of the prodynorphin gene and cocaine dependence.

Am J Med Genet B Neuropsychiatr Genet 2005 Nov;139B(1):106-8

Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania School of Medicine, Clinical Research Building, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1002/ajmg.b.30238DOI Listing
November 2005

Lack of association between single nucleotide polymorphisms in the corticotropin releasing hormone receptor 1 (CRHR1) gene and alcohol dependence.

J Psychiatr Res 2005 Sep 20;39(5):475-9. Epub 2005 Jan 20.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.jpsychires.2004.12.004DOI Listing
September 2005

No association between common variations in the human alpha 2 subunit gene (ATP1A2) of the sodium-potassium-transporting ATPase and idiopathic generalized epilepsy.

Neurosci Lett 2005 Jul 1-8;382(1-2):33-8

Department of Psychiatry, University of Pennsylvania School of Medicine, Center for Neurobiology and Behavior, 3535 Market Street, 2nd Floor, R2070, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.neulet.2005.02.057DOI Listing
July 2005

No association between common variations in the neuronal nicotinic acetylcholine receptor alpha2 subunit gene (CHRNA2) and bipolar I disorder.

Psychiatry Res 2005 Jun;135(3):171-7

School of Medicine Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Clinical Research Building, Room 135a, 415 Curie Boulevard, Philadelphia, PA 19104-6140, USA.

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http://dx.doi.org/10.1016/j.psychres.2005.04.004DOI Listing
June 2005