Publications by authors named "Faisal J Alibhai"

22Publications

Understanding systemic factors in aging and rejuvenation.

Aging (Albany NY) 2020 11 13;12(21):20936-20937. Epub 2020 Nov 13.

Toronto General Hospital Research Institute, Division of Cardiovascular Surgery, University Health Network, Toronto, Ontario, Canada.

View Article and Find Full Text PDF
November 2020

Circadian mutant mice with obesity and metabolic syndrome are resilient to cardiovascular disease.

Am J Physiol Heart Circ Physiol 2020 11 28;319(5):H1097-H1111. Epub 2020 Sep 28.

Centre for Cardiovascular Investigations, Department of Biomedical Sciences, University of Guelph, Guelph, Ontario, Canada.

View Article and Find Full Text PDF
November 2020

Considering Cause and Effect of Immune Cell Aging on Cardiac Repair after Myocardial Infarction.

Cells 2020 08 13;9(8). Epub 2020 Aug 13.

Division of Cardiovascular Surgery, Toronto General Hospital Research Institute, University Health Network, Toronto, ON M5T 1P5, Canada.

View Article and Find Full Text PDF
August 2020

Rectification of radiotherapy-induced cognitive impairments in aged mice by reconstituted Sca-1 stem cells from young donors.

J Neuroinflammation 2020 Feb 7;17(1):51. Epub 2020 Feb 7.

Toronto General Hospital Research Institute, University Health Network, Toronto Medical Discovery Tower, Room 3-702, 101 College Street, Toronto, Ontario, M5G 1L7, Canada.

View Article and Find Full Text PDF
February 2020

Targeting aged bone marrow for systemic rejuvenation.

Aging (Albany NY) 2020 02 6;12(3):2024-2025. Epub 2020 Feb 6.

Toronto General Hospital Research Institute, Toronto General Hospital, Toronto, ON, Canada.

View Article and Find Full Text PDF
February 2020

SR9009 administered for one day after myocardial ischemia-reperfusion prevents heart failure in mice by targeting the cardiac inflammasome.

Commun Biol 2019 3;2:353. Epub 2019 Oct 3.

1Centre for Cardiovascular Investigations, Department of Biomedical Sciences, University of Guelph, Guelph, Ontario N1G2W1 Canada.

View Article and Find Full Text PDF
April 2020

CD34 Stem Cells: Promising Roles in Cardiac Repair and Regeneration.

Can J Cardiol 2019 10 11;35(10):1311-1321. Epub 2019 Jun 11.

Toronto General Hospital Research Institute, Division of Cardiovascular Surgery, University Health Network, Toronto, Ontario, Canada; Division of Cardiac Surgery, Department of Surgery, University of Toronto; Toronto, Ontario, Canada. Electronic address:

View Article and Find Full Text PDF
October 2019

Long-term repopulation of aged bone marrow stem cells using young Sca-1 cells promotes aged heart rejuvenation.

Aging Cell 2019 12 5;18(6):e13026. Epub 2019 Aug 5.

Division of Cardiovascular Surgery, Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.

View Article and Find Full Text PDF
December 2019

Knockout of Canopy 2 activates p16 pathway to impair cardiac repair.

J Mol Cell Cardiol 2019 07 29;132:36-48. Epub 2019 Apr 29.

Toronto General Hospital Research Institute, Division of Cardiovascular Surgery, University Health Network, Toronto, ON, Canada; Division of Cardiac Surgery, Department of Surgery, University of Toronto, Toronto, ON, Canada. Electronic address:

View Article and Find Full Text PDF
July 2019

Novel mediators of aneurysm progression in bicuspid aortic valve disease.

J Mol Cell Cardiol 2019 07 29;132:71-83. Epub 2019 Apr 29.

Division of Cardiovascular Surgery, Toronto General Hospital Research Institute and Peter Munk Cardiac Centre, University Health Network, Toronto, ON, Canada; Department of Surgery, Division of Cardiac Surgery, University of Toronto, Toronto, ON, Canada. Electronic address:

View Article and Find Full Text PDF
July 2019

Commentary: Circulating factors released after myocardial infarction: Beneficial or detrimental?

J Thorac Cardiovasc Surg 2019 06 8;157(6):2270-2271. Epub 2018 Nov 8.

Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada; Division of Cardiac Surgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada. Electronic address:

View Article and Find Full Text PDF
June 2019

Emerging roles of extracellular vesicles in cardiac repair and rejuvenation.

Am J Physiol Heart Circ Physiol 2018 10 27;315(4):H733-H744. Epub 2018 Jun 27.

Division of Cardiovascular Surgery, Toronto General Hospital Research Institute, University Health Network , Toronto, Ontario , Canada.

View Article and Find Full Text PDF
October 2018

Female ClockΔ19/Δ19 mice are protected from the development of age-dependent cardiomyopathy.

Cardiovasc Res 2018 02;114(2):259-271

Department of Biomedical Sciences/OVC, Centre for Cardiovascular Investigations, University of Guelph, Room 1646B, University of Guelph, Guelph, ON N1G2W1, Canada.

View Article and Find Full Text PDF
February 2018

Disrupting the key circadian regulator CLOCK leads to age-dependent cardiovascular disease.

J Mol Cell Cardiol 2017 04 20;105:24-37. Epub 2017 Feb 20.

Centre for Cardiovascular Investigations, Department of Biomedical Sciences, University of Guelph, Guelph, Ontario, Canada. Electronic address:

View Article and Find Full Text PDF
April 2017

Consequences of Circadian and Sleep Disturbances for the Cardiovascular System.

Can J Cardiol 2015 Jul 26;31(7):860-72. Epub 2015 Jan 26.

Cardiovascular Research Group, Department of Biomedical Sciences, University of Guelph, Ontario, Canada. Electronic address:

View Article and Find Full Text PDF
July 2015

Male-Specific Cardiac Dysfunction in CTP:Phosphoethanolamine Cytidylyltransferase (Pcyt2)-Deficient Mice.

Mol Cell Biol 2015 Aug 18;35(15):2641-57. Epub 2015 May 18.

Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, Canada

View Article and Find Full Text PDF
August 2015

Therapeutic applications of circadian rhythms for the cardiovascular system.

Front Pharmacol 2015 17;6:77. Epub 2015 Apr 17.

Cardiovascular Research Group, Department of Biomedical Sciences, University of Guelph Guelph, ON, Canada.

View Article and Find Full Text PDF
May 2015

Relaxin peptide hormones are protective during the early stages of ischemic stroke in male rats.

Endocrinology 2015 Feb 2;156(2):638-46. Epub 2014 Dec 2.

Department of Biomedical Sciences (L.H.B., J.M.W., F.J.A., A.J.S.S.), Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada N1G2W1; Department of Biomedical Sciences (B.J.C., T.M.S.), Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, Prince Edward Island, Canada C1A4P3; and Department of Biology (B.C.W.), Acadia University, Wolfville, Nova Scotia, Canada B4P2R6.

View Article and Find Full Text PDF
February 2015

Circadian regulation of myocardial sarcomeric Titin-cap (Tcap, telethonin): identification of cardiac clock-controlled genes using open access bioinformatics data.

PLoS One 2014 14;9(8):e104907. Epub 2014 Aug 14.

Cardiovascular Research Group, Department of Biomedical Sciences, University of Guelph, Guelph, Ontario, Canada.

View Article and Find Full Text PDF
March 2016