Publications by authors named "Faiçal Slimani"

17 Publications

  • Page 1 of 1

Parotid Ewing's sarcoma: Extra-skeletal uncommon condition.

Ann Med Surg (Lond) 2021 May 13;65:102304. Epub 2021 Apr 13.

Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco.

Introduction: The parotid gland is a very rare location of Ewing's sarcoma. Its clinical and radiological manifestations are atypical. Its management is based on a multidisciplinary approach to improve prognosis and survival.

Discussion: The diagnosis of parotid Ewing's sarcoma is determined by a combination of genetic and histological criteria. Its local aggressiveness and high metastatic potential require prompt and appropriate management. Many prognostic features affect its management, the most important is the TNM staging.

Conclusion: Limited cases of parotid Ewing's sarcoma have been published in the literature. This small number of reported cases is the only way to study its characteristics.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amsu.2021.102304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080453PMC
May 2021

Scorfuloderma of cheek (a cutaneous tuberculosis colliquativa cutis): Case report.

Ann Med Surg (Lond) 2021 Apr 26;64:102257. Epub 2021 Mar 26.

Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco.

Introduction: Scrofuloderma is the most common form of cutaneous tuberculosis. The facial location is unusual and requires special care.

Discussion: The diagnosis of cutaneous tuberculosis is difficult due to the polymorphism of the anatomo-clinical pictures as well as the difficulty of isolating the causal agent. The combination of a range of clinical and paraclinical arguments justifies starting antibacillary treatment.

Conclusion: Tuberculosis is endemic disease in our country; this endemicity is attested by the multiple cases of cutaneous tuberculosis reported in the literature.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amsu.2021.102257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040098PMC
April 2021

Chronical rhino-orbital mucormycosis in an immunocompetent host: A case report.

Int J Surg Case Rep 2021 Apr 10;82:105882. Epub 2021 Apr 10.

Faculté de Médecine et Pharmacie, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco; Service de Stomatologie et chirurgie Maxillo-faciale, Hôpital 20 Août, CHU Ibn Rochd, B.P 2698, Casablanca, Morocco.

Mucormycosis is an opportunistic fungal infection caused by molds within the order Mucorales. The rhino-orbital-cerebral localization is the most frequent. It is a destructive, necrotizing and potentially fatal disease. The treatment involves aggressive surgical debridement combined with antifungal drugs. The course is quickly fatal in the event of delayed diagnosis and / or treatment. This infection usually affects immunocompromised and diabetic patients, but cases of mucormycosis in immunocompetents are increasingly reported. Chronic mucormycosis is extremely rare and affects both immunocompromised and immunocompetent patients, its clinical evolution is nonspecific and its treatment is not standardized. We report the case of a destructive rhino-orbital and pulmonary involvement in a 59 years old immunocompetent patient who presented a right periorbital edema associated and a vision loss and a notion of nasal obstruction and progressive onset headache four months before admission. Her condition progressed with rapidly extensive necrosis. She underwent extensive surgical resection but soon succumbed to multiple organ failure. The diagnosis of mucormycosis was confirmed post mortem on the excisional piece. The purpose of this article is to draw attention to chronic mucormycosis in the immunocompetent and to emphasize the importance of early diagnosis and adequate management of this fatal infection.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijscr.2021.105882DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079271PMC
April 2021

Arteriovenous malformation in cheek and tongue aggravated by cellulitis: A case report and literature review.

Ann Med Surg (Lond) 2021 Mar 26;63:102196. Epub 2021 Feb 26.

Department of Stomatology and Maxillofacial Surgery, 20 August 1953 Hospital, Ibn Rochd, B.P 2698, Casablanca, Morocco.

Arterio-venous malformation (AVM) is a congenital disorder of blood vessels, causing abnormal passage of blood between the artery and vein, which most often results in abnormal development of the vascular system in embryonic life. Arteriovenous malformations of the head and neck pose a challenging therapeutic and reconstructive problem. We present a rare case of a 22-year-old white woman, who complained of facial asymmetry on the right side, evolving after an episode of jugular cellulite of dental origin treated 6 months ago. Clinical examination revealed a palpable nodule measuring approximately 25 mm, soft, painless, of sub-mucosal location and a swollen, bluish right hemi tongue. Ultrasonography was requested, which indicated the hypothesis of a vascular lesion. The microscopic diagnosis was of arterio-venous malformation with thrombus formation. The patient has been followed for 3 months and is without signs of relapse. We treated the cellulite and closely followed the patient.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amsu.2021.102196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933698PMC
March 2021

SURGICEL mimicking a recurrence of a temporomandibular joint chondrosarcoma.

Ann Med Surg (Lond) 2021 Mar 23;63:102187. Epub 2021 Feb 23.

Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco.

Introduction: The hemostatic agents have increased the bleeding complication in many surgeries. The SURGICEL is a preparation of oxidized cellulose regenerated from alpha-cellulose in an organic solvent, this product has the characteristic of resorbing without having a reaction of foreign body in 4-8 weeks.

Case Presentation: We report the case of a patient operated on for a chondrosarcoma of the right temporomandibular joint with normal postoperative consequences, nevertheless after 3 months, the patient consulted again for the same symptomatology. To rule out tumor recurrence, magnetic resonance imaging has been requested; which showed a lesion well limited in T1 hypointense and heterogeneous in T2. During the surgical revision, we discover the presence of a reworked fibrous material, this material was the surgicel used for hemostatic purposes during the first surgery.

Discussion: Hemostatic agents significantly reduced bleeding complications. But some authors are observed that some substances can persisted after 8 weeks of using, clinical manifestations depend of operative site. The diagnosis is suspected behind an imaging resonance aspect of a lesion well limited in T1 hypointense and heterogeneous in T2, but the discovery of a reworked fibrous materiel when the revision can confirm it.

Conclusion: the absence of degradation of the surgicel can clinically mimic a superinfection or even tumor recurrence; imaging guide the diagnosis but only the surgical revision can confirm it.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amsu.2021.102187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921749PMC
March 2021

Management of mandibular angle fractures through single and two mini-plate fixation systems: Retrospective study of 112 cases.

Int J Surg Case Rep 2021 Mar 23;80:105690. Epub 2021 Feb 23.

Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco; Oral and Maxillofacial Surgery Department, CHU Ibn Rochd, B.P 2698, Casablanca, Morocco.

Introduction: The aim of this paper is to compare the clinical results between the different methods of fixation of standard mini-plates for the management of mandibular angle fractures.

Study Design: This was a retrospective analysis study of 196 patients with mandibular angle fractures divided into 3 groups at our hospital 20 august 1953 specialist hospital, which is a referral center between January 2015 and January 2020. The patients were assessed for malocclusion, infection, wound dehiscence, neuro-sensory deficit, mouth opening, stability, operating time, blood loss, and hardware failure. Group (I) comprised 72 men and 40 women with a mean age of 43 years. Group (II) comprised 36 men and 12 women with a mean age of 47 years. Group (II) comprised 29 men and 7 women with a mean age of 33 years. The assessment of surgical outcomes after the last follow-up visit clearly showed a lack of stability in patients group II compared to the other groups. The operating time was reduced in group I compared to Group II/ III. (P = 0.03) The wound dehiscence occurred mostly in Group III unless it was statistically no significant. The infection events occurred in 36 patients of the sample, which was not statistically significant (Table 4).

Discussion: Fractures of the mandibular angle represent 23-42% of all mandibular fractures, in our context road accidents followed by aggression are the most frequent mechanisms found. A various types of treatment approaches for the treatment of angular fractures have been described. Our analysis revealed that surgical time and complication rate has been reduced when using the Group I technique compared to the other groups.

Conclusion: The use of the monocortical external oblique miniplate provides the best results. Successful treatment of mandibular fractures depends on stability in the ideal anatomical position since abnormal mobility at the fracture site will lead to non-union, malocclusion, and infection.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijscr.2021.105690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921495PMC
March 2021

Restorative management of human bite injuries to the face: Case series.

Ann Med Surg (Lond) 2021 Feb 19;62:249-252. Epub 2021 Jan 19.

Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco.

Facial skin wounds are common problems seen and treated by emergency centers around the world. Among all wounds, cat and dog bites are frequently seen. Human bite injuries are both deceptive and difficult in their presentation and management. The injuries have a disfiguration effect with possible psychological impact on the patient. The aim of this paper is to compare experience with human bites of the face in our surgical unit, with other similar trials in term of reasons for the circumstances of injuries, age, and sex of the patients, site of injury, pan-time between consultation and treatment, incidence of infection and surgical management. Data in terms of age, gender distribution, circumstances of injury, location of injuries, evolution of surgical management and complications were recorded. We report here a series of 10 cases of human bite wounds to the face, admitted to our department, and treated with different reconstruction procedures.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amsu.2021.01.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840440PMC
February 2021

Melanoma of the oral cavity: A silent killer.

Ann Med Surg (Lond) 2021 Feb 18;62:182-185. Epub 2021 Jan 18.

Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco.

Melanoma of the mouth is a rare entity of cancer. It has a bad prognosis. We report two cases of mouth melanoma. In the first case, 68 years old man developed a mandibular gingival tumor. Head and neck MRI scans showed an aggressive tumor process in the mouth with bone extension and in the deep spaces. The patient was free of cervical lymph nodes. The second case is a 75-years-old male with heavy tobacco smoke. The man felt a burgeoning mass on the right palate. The neck palpation found a firm mobile non-tender mass at the left upper jugular region. The anatomopathological study of the biopsies assigned both cases to malignant melanoma. Because of the rarity and delays in diagnosis, case reports are an invaluable source of information.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amsu.2021.01.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829076PMC
February 2021

Cavernous Sinus Thrombosis related to Orbital Cellulitis Serious Complication to Prevent: a case report and literature review.

Ann Med Surg (Lond) 2021 Feb 18;62:179-181. Epub 2021 Jan 18.

Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco.

Introduction: The authors report a case which aims to underline the importance of multidisciplinary management and rapid diagnosis of orbital cellulitis, for an adequate treatment of ocular damages and related complications, to prevent serious and permanent sequelae and avoid a fatal prognosis.

Presentation Of Case: A 61-year-old female reported to the oral and maxillofacial surgery department after she was dragged around for two months. She presented with a right facial swelling and orbital apex syndrome including proptosis, ophthalmoplegia and ptosis.

Discussion: Complications of orbital cellulitis may be limited to the orbit, such as subperiosteal or orbital abscess, optic neuritis, blindness, or intracranial such as meningitis, sinus cavernous thrombosis, cerebral abscess and even death.

Conclusion: Maxillofacial surgeons must be aware of this complication in a multidisciplinary context to adopt adequate treatment as soon as possible.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amsu.2021.01.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829077PMC
February 2021

The deltopectoral flap in full-thickness cheek defect: A case report.

Ann Med Surg (Lond) 2021 Feb 18;62:119-122. Epub 2021 Jan 18.

Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, B.P, 5696, Casablanca, Morocco.

Introduction: Defects caused after tumor resection should be closed with flaps that match the neighboring cheek's skin.

Presentation Of Case: the authors report a patient diagnosed with squamous cell carcinoma and its management. A 50-year-old man patient presented with a painless slow swelling in the left cheek, which had increased in size in the last four months, tobacco smoking, and alcohol intake for 15 years. Clinical examination revealed left cheek swelling without any lymph nodes at the palpation.

Discussion: Reconstruction of the full-thickness is a real challenge. The deltopectoral flap offers several advantages despite the increasing use of microvascular reconstruction; technically is a simple and reliable flap that is preferred for the reconstruction of large through-and-through defects after resection of oral carcinoma. Preoperative planning of flap and early recognition of issues can avoid postoperative complications.

Conclusion: This reconstruction technique was demonstrated in large, full-thickness defects involving the cheek.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amsu.2021.01.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819807PMC
February 2021

Rehabilitation of facial palsy by the lengthening temporalis myoplastie: A case report.

Ann Med Surg (Lond) 2021 Feb 5;62:10-12. Epub 2021 Jan 5.

Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco.

Introduction: The lengthening temporalis myoplasty (LTM) is defined as a transfer of the entire temporal muscle from the coronoid process to the labial commissure reinserted into the orbicularis muscle.

Presentation Of Case: a 60-year-old man with grade III longstanding facial paralysis of the right hemi-face secondary to a right total parotidectomy. The surgery was performed for the rehabilitation of the right hemi-facial side by the lengthening temporalis myoplasty. The follow-up was favorable with improvement of the facial dynamics.

Discussion: Surgical management of the longstanding facial palsy is a real challenge. The lengthening temporalis myoplasty offers several advantages; technically is a simple. This technique was demonstrated in severe neglected facial palsy and is performed when there is a definitive complete, or almost complete, loss of the facial nerve and the trigeminal is preserved. Effective rehabilitation through training and physical therapy is necessary to optimize results.

Conclusion: Facial palsy should no longer be permanent, surgical techniques as lengthening temporalis myoplasty with early postoperative physiotherapy leads to good results. Preoperative planning and early recognition of issues can avoid postoperative complications.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amsu.2020.12.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804336PMC
February 2021

Lipofilling as an aesthetic restorative technique for the facial hemiatrophy of Parry-Romberg syndrome: An analysis of 27 cases.

Int J Surg Case Rep 2021 Feb 9;79:138-141. Epub 2021 Jan 9.

Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco; Oral and Maxillofacial Surgery Department, CHU Ibn Rochd, B.P 2698, Casablanca, Morocco.

Introduction: The aim of this paper is to present our experience using autologous fat transplantation for facial augmentation and to evaluate the effectiveness of lipofilling in different regions of the face for the reconstruction and aesthetic improvement of the facial contouring.

Case Presentation: Data in term to the age, gender distribution, harvest and injection sites, degree of satisfaction with post-surgical facial, and complications were recorded.

Discussion: Progressive haemifacial atrophy, also Known as Parry Romberg's disease, is a common craniofacial disease that conventionally affects the subcutaneous tissue on one side of the face. We report here a series of 27cases of hemifacial atrophy (Parry-Romberg syndrome), admitted to our department, and treated with lipofilling in conformity with Coleman's guidelines. The volume of fat grafting was assessed by an attempt to reach symmetry with the controlateral side within a single procedure.

Conclusion: All patients claimed that they were satisfied or very satisfied with the aesthetic results and affirmed that it had a positive psychological impact on their daily life.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijscr.2021.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817425PMC
February 2021

Central Giant cell tumor of jaw bone in child: A case report.

Int J Surg Case Rep 2021 Feb 6;79:97-100. Epub 2021 Jan 6.

Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco; Oral and Maxillofacial Surgery Department, CHU Ibn Rochd, B.P 2698, Casablanca, Morocco.

Introduction: Central giant cell tumors (CGCTs) bones are uncommon benign bone tumors in the jaw.

Presentation Of Case: The authors report a pediatric patient who was diagnosed with an aggressive central giant cell cyst of the mandible and its management. The CGCT usually occurs in adolescents patients from 5 to 10 years of age. An 8-year-old female patient presented with progressive non-pulsatile swelling of the mandible. Intraoral examination revealed mobility of teeth, associated with gingival swelling.

Discussion: Common sites of giant cell tumors are the epiphysis of the long bones. Giant cell tumors accounted for 4-7% of all primary bone tumors. The mandible localization is exceptional, the main treatment for giant cell tumors is surgical excision and different surgical approaches had been reported in the literature thus depending on the size of the cyst, localization, and experience of the surgeon.

Conclusion: Giant cyst tumor of the jaw is rare and less common in childhood. The clinical behavior is very diverse. The main treatment is surgical removal and follow-up to reveal recurrence.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijscr.2021.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806938PMC
February 2021

An early orbital metastasis from breast cancer: A case report.

Int J Surg Case Rep 2021 Jan 18;78:300-302. Epub 2020 Dec 18.

Faculté de Médecine et Pharmacie, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco; Service de Stomatologie et chirurgie Maxillo-faciale, Hôpital 20 Août, CHU Ibn Rochd, B.P 2698, Casablanca, Morocco.

Introduction: Orbital metastases from solid cancers are infrequent or underestimated, since they represent only 1-13% of tumors of the orbit. They are even less frequent in breast cancer and are rarely diagnosed. We report a case of an early diagnosed orbital metastasis from breast cancer to an extra ocular muscle.

Case Report: We report the case of a 33-year-old female patient who presented, following the diagnosis of her breast cancer, headache, a progressive decrease in visual acuity of the right eye and diplopia. Brain imaging revealed a tissue process at the expense of the internal rectus muscle, which biopsy pointed to a secondary lesion of breast cancer.

Discussion: Extraocular muscles are rarely infiltrated by metastasis from distant sites. They are mostly asymptomatic and suggest a systematic spread of the disease. The treatment is generally palliative and the prognosis is generally poor.

Conclusion: Orbital metastases from breast cancer are certainly rare but are associated with significant morbidity. In order to make a precise diagnosis and offer an appropriate treatment, healthcare professionals must remain vigilant in the face of any ophthalmological symptoms.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijscr.2020.12.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777453PMC
January 2021

Salivary parotid cyst as an occurred complication of Subangulomandibular approach of mandibular subcondylar fracture: A case report.

Ann Med Surg (Lond) 2020 Dec 1;60:673-674. Epub 2020 Dec 1.

Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, B.P, 5696, Casablanca, Morocco.

Introduction: A number of papers exist about post-traumatic silaocele. Iatrogenic sialocele has been described as complication of parotid surgery but there is no specific data about the cases of sialocele and salivary duct surgical injury in condylar fracture management.

Presentation Of Case: A 36-year-old man was reported to the maxillofacial emergency department for mandibular sub-condylar fracture and internal fixation of the sub-condylar fracture was planned. Postoperatively he presented a salivary cyst which was managed by conservative treatment.

Discussion: Iatrogenic injury to the salivary duct and sialocele formation observed in the post-operative period of surgical treatment of a condylar fracture by sub-angulomandibular approach. Maxillofacial surgeons should be aware of this complication and the importance of adopting a conservative treatment whenever it is possible. Botulinum toxin injections can be performed as a first-line treatment for these complications.

Conclusion: A conservative management was adopted by pressure dressings and percutaneous needle aspiration of the swelling, which was useful to absorb cystic content and helped healing.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amsu.2020.11.078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721658PMC
December 2020

Assessment of artery calcification in atherosclerosis with dynamic 18F-FDG-PET/CT imaging in elderly subjects.

Int J Cardiovasc Imaging 2019 May 2;35(5):947-954. Epub 2019 Feb 2.

Department of Nuclear Medicine and Radiobiology, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001, 12th Avenue North, Sherbrooke, QC, J1H 5N4, Canada.

Glucose metabolism in atherosclerotic arteries has been shown to be an indicator of inflammation, which might be a precursor of plaque rupture. In this prospective study, we assessed the correlation between artery calcification and glucose metabolism by means of 18F-FDG PET/CT imaging in elderly subjects. Nineteen elderly subjects, with age ranging from 65 to 85 years, underwent CT and dynamic 18F-FDG-PET imaging. The artery calcification was determined with a threshold of 130 Hounsfield units. Intensity of calcification and ratio of calcification area to total artery area were classified in four sequential classes from CT images. The CT artery images were also classified as having single or multi-spot calcifications. Their respective glucose metabolism was assessed with fractional uptake rate (FUR). Factor analysis was used in this study to separate blood images from tissue to extract the blood time activity curves for FUR calculations. The artery images in PET data were corrected for partial volume effect. The total arterial segments analyzed were 1332, with 1085 without calcification (81%), 247 (19%) with calcification, and 94 segments were having multi-spot of calcifications. There was a statistically significant difference in FUR values between non-calcified to calcified segments and between subjects under medication to non-medication when comparing the subjects based on calcification area. No statistically significant differences of FUR were found between single spot as a function of intensity, while in the multi-spots, there was a statistically significant difference for all artery segments. Metabolism activity varies for non-calcified to calcified segments. Based on the metabolic activity represented by FUR, calcifications in multi-spots have different effects than in single spots.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10554-019-01527-7DOI Listing
May 2019

G4DARI: Geant4/GATE based Monte Carlo simulation interface for dosimetry calculation in radiotherapy.

Comput Med Imaging Graph 2018 07 1;67:30-39. Epub 2018 May 1.

Faculty of Medicine and Health Sciences, Université de Sherbrooke, Canada. Electronic address:

Monte Carlo (MC) simulation is widely recognized as an important technique to study the physics of particle interactions in nuclear medicine and radiation therapy. There are different codes dedicated to dosimetry applications and widely used today in research or in clinical application, such as MCNP, EGSnrc and Geant4. However, such codes made the physics easier but the programming remains a tedious task even for physicists familiar with computer programming. In this paper we report the development of a new interface GEANT4 Dose And Radiation Interactions (G4DARI) based on GEANT4 for absorbed dose calculation and for particle tracking in humans, small animals and complex phantoms. The calculation of the absorbed dose is performed based on 3D CT human or animal images in DICOM format, from images of phantoms or from solid volumes which can be made from any pure or composite material to be specified by its molecular formula. G4DARI offers menus to the user and tabs to be filled with values or chemical formulas. The interface is described and as application, we show results obtained in a lung tumor in a digital mouse irradiated with seven energy beams, and in a patient with glioblastoma irradiated with five photon beams. In conclusion, G4DARI can be easily used by any researcher without the need to be familiar with computer programming, and it will be freely available as an application package.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.compmedimag.2018.04.008DOI Listing
July 2018