Professor Fahd Al-Mulla, MD, PhD, PCTM, FRCP - Kuwait University/Genatak - Director

Professor Fahd Al-Mulla

MD, PhD, PCTM, FRCP

Kuwait University/Genatak

Director

Kuwait, Mirqab | Kuwait

Main Specialties: Biochemical Genetics, Medical Genetics, Molecular Genetic Pathology, Pathology-Anatomic & Clinical

Additional Specialties: Genomic Medicine

ORCID logohttps://orcid.org/0000-0001-5409-3829


Top Author

Professor Fahd Al-Mulla, MD, PhD, PCTM, FRCP - Kuwait University/Genatak - Director

Professor Fahd Al-Mulla

MD, PhD, PCTM, FRCP

Introduction

Fahd Al-Mulla is professor of molecular pathology and genomic medicine at Kuwait University, Head of functional genomics at DDI and adjunct Faculty at Marshall University, Joan C. Edwards School of Medicine USA. Fahd established 2 laboratories at Kuwait University; The former is a large research core facility that serves about 600 academics, students and researchers and the latter is a molecular diagnostic laboratory that he heads.
Fahd has pioneered the use of next generation sequencing and microarrays in diagnostics and precision medicine. His research activities focus on cancer and diabetes. His research led to the identification of two novel metastasis suppressor genes, namely Carbonyl Reductase and Raf Kinase Inhibitory Proteins, which he and his team characterized further and their therapeutic roles in cancer patented. In the last 5-years, Fahd’s work focused more intensely on wound healing and angiogenesis defects in a genetic rat model of type II diabetes mellitus. He and his colleagues were not only able to ameliorate insulin resistance in these rat models, but also understand the precise molecular defects predisposing the animals to diabetes. By using wide genome array technology along with precise RNAi and protein inhibitors, he and his team were able to enhance wound closure, angiogeneisis and mitigate cellular senescence in these animals.
Fahd has spearheaded and initiated the ‘Genome Arabia’ project, which is a new technological milestone aiming at sequencing normal Arab individuals from Kuwait, Qatar, Bahrain, UAE, and Lebanon.
Fahd received his Medical License and Ph.D. from Glasgow University. He is a Fellow of the Royal College of Physicians of Edinburgh. Fahd Al-Mulla has extensive experience in genomic-related technologies and intellectual property development. He currently holds 6 patents related to diabetes, wound healing and cancer. He established two offices for Technology Transfer and Patenting one at Kuwait University and the other at DDI.
As an author for Nature’s Biotechnology blog, his mandate is to build collaborative partnerships, invest institutional outputs, generate capital and resources, and promote public awareness regarding the importance of scientific research in resolving the Arab society’s problems especially pertaining to diabetes, obesity and cancer. To that end, Fahd serves as Chair of the Evidence group in the Global Genomic Medicine Collaborative and served as a Chair of the International Confederation of Countries Advisory Council of the Human Variome Project.

Contact:
Email: fahd@al-mulla.org
Phone: +965 67771040
Websites: http://www.al-mulla.org

Primary Affiliation: Kuwait University/Genatak - Kuwait, Mirqab , Kuwait

Specialties:

Additional Specialties:


View Professor Fahd Al-Mulla’s Resume / CV

Education

Jun 1999
Glasgow University
PhD
Jun 1993
Glasgow University
M.B.Ch.B
MD

Experience

Apr 2019
Genomic Medicine
Head
28-years experience
Apr 2019
Genomic Medicine
Head
28-years experience

Publications

224Publications

3061Reads

-Profile Views

1058PubMed Central Citations

Autoimmune signatures for prediction and diagnosis of autoimmune diabetes in Kuwait.

Autoimmun Rev 2019 Jun 5;18(6):642-644. Epub 2019 Apr 5.

Medical Division, Dasman Diabetes Institute, Kuwait.

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http://dx.doi.org/10.1016/j.autrev.2019.02.009DOI Listing
June 2019
24 Reads
7.933 Impact Factor

TNF-α Drives the CCL4 Expression in Human Monocytic Cells: Involvement of the SAPK/JNK and NF-κB Signaling Pathways.

Cell Physiol Biochem 2019 ;52(4):908-921

Animal and Zebrafish Core Facility, Dasman Diabetes Institute, Kuwait City, Kuwait.

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https://www.cellphysiolbiochem.com/Articles/000063/
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http://dx.doi.org/10.33594/000000063DOI Listing
April 2019
15 Reads
2.875 Impact Factor

TNF-α Induces a Pro-Inflammatory Phenotypic Shift in Monocytes through ACSL1: Relevance to Metabolic Inflammation.

Cell Physiol Biochem 2019 8;52(3):397-407. Epub 2019 Mar 8.

Immunology Unit, Dasman Diabetes Institute, Kuwait-City, Kuwait,

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http://dx.doi.org/10.33594/000000028DOI Listing
March 2019
1 Read
2.875 Impact Factor

A Perception on Genome-Wide Genetic Analysis of Metabolic Traits in Arab Populations.

Front Endocrinol (Lausanne) 2019 28;10. Epub 2019 Jan 28.

Genetics and Bioinformatics Unit, Dasman Diabetes Institute, Kuwait City, Kuwait.

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http://dx.doi.org/10.3389/fendo.2019.00008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362414PMC
January 2019
125 Reads

Pathogenic Germline Variants in 10,389 Adult Cancers.

Cell 2018 04;173(2):355-370.e14

Department of Medicine, Washington University in St. Louis, Saint Louis, MO 63108, USA; McDonnell Genome Institute, Washington University in St. Louis, Saint Louis, MO 63108, USA; Department of Genetics, Washington University in St. Louis, Saint Louis, MO 63108, USA; Siteman Cancer Center, Washington University in St. Louis, Saint Louis, MO 63108, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.03.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949147PMC
April 2018
44 Reads
32.242 Impact Factor

Test Pricing and Reimbursement in Genomic Medicine: Towards a General Strategy.

Public Health Genomics 2016 28;19(6):352-363. Epub 2016 Sep 28.

Laboratory of Health Economics and Management, Department of Economics, University of Piraeus, Piraeus, Greece.

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http://dx.doi.org/10.1159/000449152DOI Listing
September 2017
48 Reads
1 Citation
2.462 Impact Factor

Identification of a rare germline NBN gene mutation by whole exome sequencing in a lung-cancer survivor from a large family with various types of cancer.

Fam Cancer 2017 07;16(3):389-394

Department of Pathology, Faculty of Medicine, Kuwait University, P.O. Box 24923, 13110, Safat, Kuwait.

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http://dx.doi.org/10.1007/s10689-016-9954-9DOI Listing
July 2017
91 Reads
1.618 Impact Factor

Defined three-dimensional culture conditions mediate efficient induction of definitive endoderm lineage from human umbilical cord Wharton's jelly mesenchymal stem cells.

Stem Cell Res Ther 2016 11 16;7(1):165. Epub 2016 Nov 16.

UIC Regenerative Medicine Research Institute, International University of Catalonia, Barcelona, Spain.

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http://dx.doi.org/10.1186/s13287-016-0426-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111269PMC
November 2016
5 Reads
1 Citation
3.368 Impact Factor

The Association of Vitamin D Receptor Polymorphisms with Multiple Sclerosis in a Case-Control Study from Kuwait.

PLoS One 2015 5;10(11):e0142265. Epub 2015 Nov 5.

Molecular Pathology Unit, Department of Pathology, Faculty of Medicine, Kuwait University, Jabriya, Kuwait.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0142265PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634763PMC
June 2016
6 Reads
4 Citations
3.234 Impact Factor

RKIP Inhibits Local Breast Cancer Invasion by Antagonizing the Transcriptional Activation of MMP13.

PLoS One 2015 26;10(8):e0134494. Epub 2015 Aug 26.

Department of Biochemistry and Cancer Biology, University of Toledo, College of Medicine, Health Science Campus, Toledo, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134494PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550449PMC
May 2016
48 Reads
1 Citation
3.234 Impact Factor

Identification of 42 Genes Linked to Stage II Colorectal Cancer Metastatic Relapse.

Int J Mol Sci 2016 Apr 28;17(5). Epub 2016 Apr 28.

Molecular Pathology Unit, Department of Pathology, Faculty of Medicine, Kuwait University, Kuwait 13110, Kuwait.

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http://dx.doi.org/10.3390/ijms17050598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881437PMC
April 2016
10 Reads
2.862 Impact Factor

Epidermal growth factor receptor mutations in nonsmall cell lung carcinoma patients in Kuwait.

J Cytol 2016 Jan-Mar;33(1):1-6

Molecular Pathology Unit, Kuwait University, Safat, Kuwait.

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http://dx.doi.org/10.4103/0970-9371.175476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782395PMC
March 2016
5 Reads
2 Citations
0.413 Impact Factor

Sulforaphane modulates telomerase activity via epigenetic regulation in prostate cancer cell lines.

Biochem Cell Biol 2016 Feb 9;94(1):71-81. Epub 2015 Sep 9.

a Department of Biological Sciences, Marshall University, 1 John Marshall Drive, Huntington, WV 25755, USA.

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http://www.nrcresearchpress.com/doi/10.1139/bcb-2015-0038
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http://dx.doi.org/10.1139/bcb-2015-0038DOI Listing
February 2016
4 Reads
3 Citations
2.152 Impact Factor

RKIP regulates CCL5 expression to inhibit breast cancer invasion and metastasis by controlling macrophage infiltration.

Oncotarget 2015 Nov;6(36):39050-61

Department of Biochemistry and Cancer Biology, University of Toledo, College of Medicine, Health Science Campus, Toledo, OH, USA.

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http://dx.doi.org/10.18632/oncotarget.5176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770756PMC
November 2015
28 Reads
6 Citations
6.359 Impact Factor

Gender influence in EBV antibody response in multiple sclerosis patients from Kuwait.

J Neuroimmunol 2015 Aug 21;285:57-61. Epub 2015 May 21.

Molecular Pathology Unit, Department of Pathology, Faculty of Medicine, Kuwait University, Kuwait.

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http://dx.doi.org/10.1016/j.jneuroim.2015.05.021DOI Listing
August 2015
23 Reads
1 Citation
2.467 Impact Factor

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.

Authors:
William H Goodson Leroy Lowe David O Carpenter Michael Gilbertson Abdul Manaf Ali Adela Lopez de Cerain Salsamendi Ahmed Lasfar Amancio Carnero Amaya Azqueta Amedeo Amedei Amelia K Charles Andrew R Collins Andrew Ward Anna C Salzberg Annamaria Colacci Ann-Karin Olsen Arthur Berg Barry J Barclay Binhua P Zhou Carmen Blanco-Aparicio Carolyn J Baglole Chenfang Dong Chiara Mondello Chia-Wen Hsu Christian C Naus Clement Yedjou Colleen S Curran Dale W Laird Daniel C Koch Danielle J Carlin Dean W Felsher Debasish Roy Dustin G Brown Edward Ratovitski Elizabeth P Ryan Emanuela Corsini Emilio Rojas Eun-Yi Moon Ezio Laconi Fabio Marongiu Fahd Al-Mulla Ferdinando Chiaradonna Firouz Darroudi Francis L Martin Frederik J Van Schooten Gary S Goldberg Gerard Wagemaker Gladys N Nangami Gloria M Calaf Graeme Williams Gregory T Wolf Gudrun Koppen Gunnar Brunborg H Kim Lyerly Harini Krishnan Hasiah Ab Hamid Hemad Yasaei Hideko Sone Hiroshi Kondoh Hosni K Salem Hsue-Yin Hsu Hyun Ho Park Igor Koturbash Isabelle R Miousse A Ivana Scovassi James E Klaunig Jan Vondráček Jayadev Raju Jesse Roman John Pierce Wise Jonathan R Whitfield Jordan Woodrick Joseph A Christopher Josiah Ochieng Juan Fernando Martinez-Leal Judith Weisz Julia Kravchenko Jun Sun Kalan R Prudhomme Kannan Badri Narayanan Karine A Cohen-Solal Kim Moorwood Laetitia Gonzalez Laura Soucek Le Jian Leandro S D'Abronzo Liang-Tzung Lin Lin Li Linda Gulliver Lisa J McCawley Lorenzo Memeo Louis Vermeulen Luc Leyns Luoping Zhang Mahara Valverde Mahin Khatami Maria Fiammetta Romano Marion Chapellier Marc A Williams Mark Wade Masoud H Manjili Matilde E Lleonart Menghang Xia Michael J Gonzalez Michalis V Karamouzis Micheline Kirsch-Volders Monica Vaccari Nancy B Kuemmerle Neetu Singh Nichola Cruickshanks Nicole Kleinstreuer Nik van Larebeke Nuzhat Ahmed Olugbemiga Ogunkua P K Krishnakumar Pankaj Vadgama Paola A Marignani Paramita M Ghosh Patricia Ostrosky-Wegman Patricia A Thompson Paul Dent Petr Heneberg Philippa Darbre Po Sing Leung Pratima Nangia-Makker Qiang Shawn Cheng R Brooks Robey Rabeah Al-Temaimi Rabindra Roy Rafaela Andrade-Vieira Ranjeet K Sinha Rekha Mehta Renza Vento Riccardo Di Fiore Richard Ponce-Cusi Rita Dornetshuber-Fleiss Rita Nahta Robert C Castellino Roberta Palorini Roslida Abd Hamid Sabine A S Langie Sakina E Eltom Samira A Brooks Sandra Ryeom Sandra S Wise Sarah N Bay Shelley A Harris Silvana Papagerakis Simona Romano Sofia Pavanello Staffan Eriksson Stefano Forte Stephanie C Casey Sudjit Luanpitpong Tae-Jin Lee Takemi Otsuki Tao Chen Thierry Massfelder Thomas Sanderson Tiziana Guarnieri Tove Hultman Valérian Dormoy Valerie Odero-Marah Venkata Sabbisetti Veronique Maguer-Satta W Kimryn Rathmell Wilhelm Engström William K Decker William H Bisson Yon Rojanasakul Yunus Luqmani Zhenbang Chen Zhiwei Hu

Carcinogenesis 2015 Jun;36 Suppl 1:S254-96

Department of Surgery, The Ohio State University College of Medicine, The James Comprehensive Cancer Center, Columbus, OH 43210, USA.

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http://carcin.oxfordjournals.org/content/36/Suppl_1/S254.ful
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http://carcin.oxfordjournals.org/content/36/Suppl_1/S254.ful
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http://www.ilcambiamento.it/files/carcinogenesi.pdf
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http://www.carcin.oxfordjournals.org/lookup/doi/10.1093/carc
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http://dx.doi.org/10.1093/carcin/bgv039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480130PMC
June 2015
200 Reads
32 Citations
5.334 Impact Factor

Disruptive chemicals, senescence and immortality.

Carcinogenesis 2015 Jun;36 Suppl 1:S19-37

Brunel Institute of Cancer Genetics and Pharmacogenomics, Health and Environment Theme, Institute of Environment, Health and Societies, Brunel University London, Kingston Lane, Uxbridge, UB8 3PH, UK.

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http://dx.doi.org/10.1093/carcin/bgv029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565607PMC
June 2015
51 Reads
4 Citations
5.334 Impact Factor

The impact of low-dose carcinogens and environmental disruptors on tissue invasion and metastasis.

Carcinogenesis 2015 Jun;36 Suppl 1:S128-59

Department of Biochemistry and Cancer Biology, Meharry Medical College, Nashville, TN 37208, USA, Department of Environmental and Occupational Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA, Department of Biology/Center for Cancer Research and Therapeutic Development, Clark Atlanta University, Atlanta, GA 30314, USA, Department of Cancer Biology, Vanderbilt University, Nashville, TN 37232, USA, Department of Pathology, Wayne State University, Detroit, MI 48201, USA, Department of Obstetrics and Gynecology, University of Melbourne, Melbourne, Victoria, Australia, Faculty of Pharmacy, Department of Pathology, Kuwait University, Safat 13110, Kuwait, Department of Otolaryngology, University of Michigan Medical College, Ann Arbor, MI 48109, USA, Department of Molecular & Cellular Biochemistry, University of Kentucky, Lexington, KY 40506, USA, Department of Environmental and Radiological Health Sciences/Food Science and Human Nutrition, College of Veterinary Medicine and Biomedical Sciences, Colorado State University/Colorado School of Public Health, Fort Collins, CO 80523-1680, USA, Center for Environmental Carcinogenesis and Risk Assessment, Environmental Protection and Health Prevention Agency, Bologna 40126, Italy, Faculty of Medicine and Health Sciences, University Putra, Serdang, Selangor 43400, Malaysia, Istituto di Genetica Molecolare, CNR, via Abbiategrasso 207, 27100 Pavia, Italy, Toxicology Research Division, Bureau of Chemical Safety Food Directorate, Health Products and Food Branch Health Canada, Ottawa, Ontario K1A0K9, Canada, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA, Centre for Advanced Research, King George's Medical University, Chowk, Lucknow, Uttar Pradesh 226003, India, Mediterranean Institute of Oncology, Viagrande 95029, Italy, Urology Department, kasr Al-Ainy School of Medicine, Cairo University, El Manial, Cairo 12515, Egypt, Department of Experimental and

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http://carcin.oxfordjournals.org/content/36/Suppl_1/S128.ful
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http://www.carcin.oxfordjournals.org/lookup/doi/10.1093/carc
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http://dx.doi.org/10.1093/carcin/bgv034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565611PMC
June 2015
45 Reads
7 Citations
5.334 Impact Factor

Genetic and epigenetic control of RKIP transcription.

Crit Rev Oncog 2014 ;19(6):417-30

Department of Biochemistry and Cancer Biology, University of Toledo, College of Medicine, Health Science Campus, Toledo, Ohio.

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February 2015
23 Reads

Regulation of the MAPK pathway by raf kinase inhibitory protein.

Crit Rev Oncog 2014 ;19(6):405-15

Systems Biology Ireland, University College Dublin, Belfield, Dublin 4, Ireland; Conway Institute of Biomolecular & Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland; School of Medicine and Medical Science, University Colle.

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February 2015
6 Reads
4 Citations

Upregulation of CREM/ICER suppresses wound endothelial CRE-HIF-1α-VEGF-dependent signaling and impairs angiogenesis in type 2 diabetes.

Dis Model Mech 2015 Jan 7;8(1):65-80. Epub 2014 Nov 7.

Department of Pathology, Kuwait University, Safat 13110, Kuwait.

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http://dx.doi.org/10.1242/dmm.017145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283651PMC
January 2015
21 Reads
2 Citations
4.973 Impact Factor

Raf kinase inhibitor protein (RKIP) blocks signal transducer and activator of transcription 3 (STAT3) activation in breast and prostate cancer.

PLoS One 2014 21;9(3):e92478. Epub 2014 Mar 21.

Department of Medicine, Rhode Island Hospital and The Alpert Medical School of Brown University, Providence, Rhode Island, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092478PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962420PMC
January 2015
27 Reads
16 Citations
3.234 Impact Factor

The locked genomes: A perspective from Arabia

Authors:
Fahd Al-Mulla

Applied & Translational Genomics

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2014
2 Reads

The locked genomes: A perspective from Arabia.

Authors:
Fahd Al-Mulla

Appl Transl Genom 2014 Dec 28;3(4):132-3. Epub 2014 Sep 28.

Department of Pathology, Molecular Pathology Unit, Faculty of Medicine, P.O. Box 24923, Safat, Kuwait 13110, Kuwait.

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http://dx.doi.org/10.1016/j.atg.2014.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888833PMC
December 2014

Molecular characterization of a population-based series of endometrial stromal sarcomas in Kuwait.

Hum Pathol 2014 Dec 4;45(12):2453-62. Epub 2014 Sep 4.

Department of Laboratory Medicine and Pathology, University of Alberta and Royal Alexandra Hospital, Edmonton, AB T5H 3V9, Canada.

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http://dx.doi.org/10.1016/j.humpath.2014.08.012DOI Listing
December 2014
8 Reads
1 Citation
2.770 Impact Factor

The influence of admixture and consanguinity on population genetic diversity in Middle East.

J Hum Genet 2014 Nov 25;59(11):615-22. Epub 2014 Sep 25.

Chinese Academy of Sciences (CAS) Key Laboratory of Computational Biology, Max-Planck Independent Research Group on Population Genomics, CAS-MPG Partner Institute for Computational Biology (PICB), Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.

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http://dx.doi.org/10.1038/jhg.2014.81DOI Listing
November 2014
29 Reads
2 Citations
2.462 Impact Factor

The population genomic landscape of human genetic structure, admixture history and local adaptation in Peninsular Malaysia.

Hum Genet 2014 Sep 11;133(9):1169-85. Epub 2014 Jun 11.

Max Planck Independent Research Group on Population Genomics, Chinese Academy of Sciences and Max Planck Society (CAS-MPG) Partner Institute for Computational Biology (PICB), Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.

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http://dx.doi.org/10.1007/s00439-014-1459-8DOI Listing
September 2014
50 Reads
5 Citations
4.824 Impact Factor

Gender-associated genomic differences in colorectal cancer: clinical insight from feminization of male cancer cells.

Int J Mol Sci 2014 Sep 29;15(10):17344-65. Epub 2014 Sep 29.

Department of Pathology, Faculty of Medicine, Health Sciences Center, Kuwait University, P.O. Box 24923, Safat 13110, Kuwait.

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http://dx.doi.org/10.3390/ijms151017344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227166PMC
September 2014
30 Reads
3 Citations
2.862 Impact Factor

Circulating cell-free DNA in sickle cell disease: is it a potentially useful biomarker?

Arch Pathol Lab Med 2014 May;138(5):678-83

From the Department of Pathology, Faculty of Medicine, Kuwait University, Kuwait City, Kuwait.

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http://dx.doi.org/10.5858/arpa.2012-0725-OADOI Listing
May 2014
61 Reads
2 Citations
2.840 Impact Factor

Raf kinase inhibitory protein role in the molecular subtyping of breast cancer.

J Cell Biochem 2014 Mar;115(3):488-97

Department of Pathology, Faculty of Medicine, Kuwait University Health Sciences Centre, Safat, 13110, Kuwait.

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http://dx.doi.org/10.1002/jcb.24682DOI Listing
March 2014
4 Reads
2 Citations
3.263 Impact Factor

Clinical implications for loss or diminution of expression of Raf-1 kinase inhibitory protein and its phosphorylated form in ductal breast cancer.

Al-Mulla F, Bitar MS, Thiery JP, Zea TT, Chatterjee D, Bennett L, Park S, Edwards J, Yeung KC, American journal of cancer research, 2013, vol. 3, no. 5, pp. 446-464

http://europepmc.org/abstract/med/24224123

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2013
1 Read

The relationship between genetic profiling, clinicopathological factors and survival in patients undergoing surgery for node-negative colorectal cancer: 10-year follow-up.

J Cancer Res Clin Oncol 2013 Dec 26;139(12):2013-20. Epub 2013 Sep 26.

Unit of Experimental Therapeutics, Institute of Cancer Science, University of Glasgow, McGregor Building, Western Infirmary Glasgow, Glasgow, G11 6NT, UK,

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http://dx.doi.org/10.1007/s00432-013-1521-2DOI Listing
December 2013
13 Reads
1 Citation
3.081 Impact Factor

Directed differentiation of umbilical cord blood stem cells into cortical GABAergic neurons.

Acta Neurobiol Exp (Wars) 2013 ;73(2):250-9

Department of Medical Laboratory Sciences (MLS), Faculty of Allied Health Sciences, Health Sciences Center, Kuwait Universiy, The State of Kuwait.

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December 2013
20 Reads
1 Citation
2.244 Impact Factor

Clinical implications for loss or diminution of expression of Raf-1 kinase inhibitory protein and its phosphorylated form in ductal breast cancer.

Am J Cancer Res 2013 1;3(5):446-64. Epub 2013 Nov 1.

Department of Pathology, Molecular Pathology Unit, Faculty of Medicine, Kuwait University, Health Sciences Centre Safat, Kuwait.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816965PMC
November 2013
22 Reads
9 Citations
3.970 Impact Factor

Prevalence and correlation of human papilloma virus and its types with prognostic markers in patients with invasive ductal carcinoma of the breast in kuwait.

Sultan Qaboos Univ Med J 2013 Nov 8;13(4):527-33. Epub 2013 Nov 8.

Department of Pathology, Faculty of Medicine, Kuwait University, Kuwait City, Kuwait.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836641PMC
November 2013
40 Reads
2 Citations

Caveolin-1/PTRF upregulation constitutes a mechanism for mediating p53-induced cellular senescence: implications for evidence-based therapy of delayed wound healing in diabetes.

Am J Physiol Endocrinol Metab 2013 Oct 13;305(8):E951-63. Epub 2013 Aug 13.

Department of Pharmacology and Toxicology, Kuwait University, Safat, Kuwait;

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http://dx.doi.org/10.1152/ajpendo.00189.2013DOI Listing
October 2013
24 Reads
8 Citations
3.790 Impact Factor

Reduced FHIT expression is associated with mismatch repair deficient and high CpG island methylator phenotype colorectal cancer.

Al-Temaimi RA, Jacob S, Al-Ali W, Thomas DA, Al-Mulla F, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2013, vol. 61, no. 9, pp. 627-638

http://europepmc.org/abstract/med/23797051

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October 2013
2 Reads

Reduced FHIT expression is associated with mismatch repair deficient and high CpG island methylator phenotype colorectal cancer.

J Histochem Cytochem 2013 Sep 24;61(9):627-38. Epub 2013 Jun 24.

Human Genetics Unit, Pathology Department, Faculty of Medicine, Health Sciences Center, Kuwait University, State of Kuwait.

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http://dx.doi.org/10.1369/0022155413497367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753890PMC
September 2013
9 Reads
7 Citations
1.960 Impact Factor

RKIP: much more than Raf kinase inhibitory protein.

J Cell Physiol 2013 Aug;228(8):1688-702

Faculty of Medicine, Department of Pathology, Kuwait University Health Sciences Centre, Safat, Kuwait.

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http://dx.doi.org/10.1002/jcp.24335DOI Listing
August 2013
22 Reads
28 Citations
3.840 Impact Factor

Immunocytochemical detection of raf kinase inhibitor protein and human papillomavirus profiling of normal and abnormal cervical ThinPrep samples.

Acta Cytol 2013 25;57(3):259-65. Epub 2013 Apr 25.

Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Kuwait University, Kuwait City, Kuwait.

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http://dx.doi.org/10.1159/000350249DOI Listing
July 2013
11 Reads
1 Citation
1.562 Impact Factor

Genetic tests obtainable through pharmacies: the good, the bad, and the ugly.

Hum Genomics 2013 Jul 8;7:17. Epub 2013 Jul 8.

Department of Pharmacy, School of Health Sciences, University of Patras, University Campus, Rion, Patras, 26504, Greece.

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http://dx.doi.org/10.1186/1479-7364-7-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711749PMC
July 2013
5 Reads
5 Citations

Decreased carbonyl reductase 1 expression promotes malignant behaviours by induction of epithelial mesenchymal transition and its clinical significance.

Cancer Lett 2012 Oct 24;323(1):69-76. Epub 2012 Apr 24.

Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Minamikogushi, Ube, Japan.

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October 2012
10 Reads
5 Citations
5.621 Impact Factor

The effect of prostate tissue inflammation in benign prostatic hyperplasia on enhancer of zeste homolog 2 ribonucleic acid expression.

Ann Saudi Med 2012 May-Jun;32(3):262-8

Department of Biochemistry, Kuwait University, Safat, Kuwait.

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http://dx.doi.org/10.5144/0256-4947.2012.262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081040PMC
October 2012
15 Reads
0.705 Impact Factor

RKIP and cellular motility.

Authors:
Fahd Al-Mulla

J Cell Physiol 2012 Jul;227(7):2969-70

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http://dx.doi.org/10.1002/jcp.23011DOI Listing
July 2012
4 Reads
1 Citation
3.840 Impact Factor

A new model for raf kinase inhibitory protein induced chemotherapeutic resistance.

PLoS One 2012 18;7(1):e29532. Epub 2012 Jan 18.

Department of Pathology, Health Sciences Center, Kuwait University, Faculty of Medicine, Safat, Kuwait.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261143PMC
July 2012
12 Reads
9 Citations
3.234 Impact Factor

Novel flavonoid didymin inhibits neuroblastomas--letter.

Authors:
Fahd Al-Mulla

Cancer Prev Res (Phila) 2012 Jun 24;5(6):883; author reply 884-5. Epub 2012 Apr 24.

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June 2012
15 Reads

Polycomb protein EZH2 regulates tumor invasion via the transcriptional repression of the metastasis suppressor RKIP in breast and prostate cancer.

Cancer Res 2012 Jun 13;72(12):3091-104. Epub 2012 Apr 13.

Department of Biochemistry and Cancer Biology, College of Medicine, Health Science Campus, University of Toledo, Toledo, Ohio, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-3546DOI Listing
June 2012
26 Reads
70 Citations
9.330 Impact Factor

ROS constitute a convergence nexus in the development of IGF1 resistance and impaired wound healing in a rat model of type 2 diabetes.

Dis Model Mech 2012 May 23;5(3):375-88. Epub 2012 Feb 23.

Department of Pharmacology and Toxicology, School of Medicine, PO Box 24923, Safat 13110, Kuwait.

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http://dx.doi.org/10.1242/dmm.007872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339831PMC
May 2012
8 Reads
11 Citations
4.973 Impact Factor

Evaluation of the PrimerDesign™ genesig real-time reverse transcription–polymerase chain reaction assay and the INFINITI® Respiratory Viral Panel Plus assay for the detection of human metapneumovirus in Kuwait

Al-Turab, M, Chehadeh, W, Al-Mulla, F & Al-Nakib, W, 2012, 'Evaluation of the PrimerDesign™ genesig real-time reverse transcription–polymerase chain reaction assay and the INFINITI® Respiratory Viral Panel Plus assay for the detection of human metapneumovirus in Kuwait', Diagnostic Microbiology a

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May 2012
2 Reads

Evaluation of the PrimerDesign™ genesig real-time reverse transcription-polymerase chain reaction assay and the INFINITI® Respiratory Viral Panel Plus assay for the detection of human metapneumovirus in Kuwait.

Diagn Microbiol Infect Dis 2012 Apr 1;72(4):358-62. Epub 2012 Feb 1.

Department of Microbiology, Faculty of Medicine, Kuwait University, Jabriya, Kuwait.

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http://dx.doi.org/10.1016/j.diagmicrobio.2012.01.001DOI Listing
April 2012
6 Reads
2.460 Impact Factor

RKIP and cellular motility

Al-Mulla, F, 2012, 'RKIP and cellular motility', Journal of Cellular Physiology, vol. 12, no. 7, pp. 981-2970.

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March 2012
1 Read

RKIP-1 and the Cell Cycle: Novel Insight Into Genomic Instability

Authors:
Fahd Al-Mulla

Forum on Immunopathological Diseases and Therapeutics

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2011
2 Reads

RAF kinase inhibitory protein (RKIP) modulates cell cycle kinetics and motility

al-Mulla, F, Bitar, M, Taqi, Z, Rath, O & Kolch, W, 2011, 'RAF kinase inhibitory protein (RKIP) modulates cell cycle kinetics and motility', Molecular BioSystems, vol. 579, no. Pt 2, p. 1891.

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2011
1 Read

Formalin-Fixed Paraffin-Embedded Tissues

Al-Mulla, F, 2011, , Humana Press, Totowa, NJ.

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2011
1 Read

FIRST INTERNATIONAL WORKSHOP ON

BONAVIDA, B, AL-MULLA, F & YEUNG, K, 2011, 'FIRST INTERNATIONAL WORKSHOP ON

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2011

Mutant K-Ras Activation of the Proapoptotic MST2 Pathway Is Antagonized by Wild-Type K-Ras

Matallanas, D, Romano, D, Al-Mulla, F, O'Neill, E, Al-Ali, W, Crespo, P, Doyle, B, Nixon, C, Sansom, O, Drosten, M, Barbacid, M & Kolch, W, 2011, 'Mutant K-Ras Activation of the Proapoptotic MST2 Pathway Is Antagonized by Wild-Type K-Ras', Molecular Cell, vol. 16, no. 6, pp. 425-906.

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2011
2 Reads

A defect in Nrf2 signaling constitutes a mechanism for cellular stress hypersensitivity in a genetic rat model of type 2 diabetes.

Bitar MS, Al-Mulla F, American journal of physiology. Endocrinology and metabolism, 2011, vol. 301, no. 6, pp. E1119-29

http://europepmc.org/abstract/med/21878664

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2011

A defect in Nrf2 signaling constitutes a mechanism for cellular stress hypersensitivity in a genetic rat model of type 2 diabetes.

Am J Physiol Endocrinol Metab 2011 Dec 30;301(6):E1119-29. Epub 2011 Aug 30.

Department of Pharmacology, Faculty of Medicine, Health Sciences Center, University of Kuwait, Safat, Kuwait.

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http://dx.doi.org/10.1152/ajpendo.00047.2011DOI Listing
December 2011
5 Reads
21 Citations
3.790 Impact Factor

Suppression of carbonyl reductase expression enhances malignant behaviour in uterine cervical squamous cell carcinoma: carbonyl reductase predicts prognosis and lymph node metastasis.

Cancer Lett 2011 Dec 13;311(1):77-84. Epub 2011 Jul 13.

Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube 755-8505, Japan.

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http://dx.doi.org/10.1016/j.canlet.2011.06.036DOI Listing
December 2011
9 Reads
6 Citations
5.621 Impact Factor

Mutant K-Ras activation of the proapoptotic MST2 pathway is antagonized by wild-type K-Ras.

Mol Cell 2011 Dec;44(6):893-906

Systems Biology Ireland, University College Dublin, Dublin 4, Ireland.

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http://dx.doi.org/10.1016/j.molcel.2011.10.016DOI Listing
December 2011
8 Reads
49 Citations
14.020 Impact Factor

Impaired TGF-β signaling and a defect in resolution of inflammation contribute to delayed wound healing in a female rat model of type 2 diabetes.

Mol Biosyst 2011 Nov 18;7(11):3006-20. Epub 2011 Aug 18.

Department of Pathology, University of Kuwait, Faculty of Medicine, Health Sciences Center, 13110, Kuwait.

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http://dx.doi.org/10.1039/c0mb00317dDOI Listing
November 2011
11 Reads
18 Citations

Estrogen receptor silencing induces epithelial to mesenchymal transition in human breast cancer cells.

PLoS One 2011 21;6(6):e20610. Epub 2011 Jun 21.

Faculty of Pharmacy, Kuwait University, Safat, Kuwait.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119661PMC
November 2011
7 Reads
40 Citations
3.234 Impact Factor

Genotypic and phenotypic differences between nodal and extranodal diffuse large B-Cell lymphomas.

J Histochem Cytochem 2011 Oct 10;59(10):918-31. Epub 2011 Aug 10.

Department of Pathology, Faculty of Medicine, Kuwait University, Safat, Kuwait.

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http://dx.doi.org/10.1369/0022155411417309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201129PMC
October 2011
31 Reads
2 Citations
1.960 Impact Factor

Human metapneumovirus in patients with respiratory tract infection in Kuwait

Al-Turab, M, Chehadeh, W, Al-Mulla, F & Al-Nakib, W, 2011, 'Human metapneumovirus in patients with respiratory tract infection in Kuwait', Journal of Medical Virology, vol. 29, no. 10, pp. 131-1817.

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August 2011
2 Reads

Whole genome amplification of DNA extracted from FFPE tissues.

Methods Mol Biol 2011 ;724:161-80

Faculty of Medicine, Department of Pathology, Kuwait University, Safat, Kuwait.

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http://dx.doi.org/10.1007/978-1-61779-055-3_11DOI Listing
June 2011
12 Reads
10 Citations

Analysis of DNA methylation in FFPE tissues using the MethyLight technology.

Methods Mol Biol 2011 ;724:191-204

King Fahad Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.

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http://dx.doi.org/10.1007/978-1-61779-055-3_13DOI Listing
June 2011
24 Reads
5 Citations

Microarray-based CGH and copy number analysis of FFPE samples.

Authors:
Fahd Al-Mulla

Methods Mol Biol 2011 ;724:131-45

Molecular Pathology Unit, Health Sciences Center, Safat, Kuwait.

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http://dx.doi.org/10.1007/978-1-61779-055-3_9DOI Listing
June 2011
4 Reads
6 Citations

RAF kinase inhibitory protein (RKIP) modulates cell cycle kinetics and motility.

Mol Biosyst 2011 Mar 23;7(3):928-41. Epub 2010 Dec 23.

Department of Pathology, University of Kuwait, Faculty of Medicine, Health Sciences Center, 13110, Kuwait.

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http://dx.doi.org/10.1039/c0mb00208aDOI Listing
March 2011
8 Reads
15 Citations

Comparison of the sensitivity and specificity of urine cytology, urinary nuclear matrix protein-22 and multitarget fluorescence in situ hybridization assay in the detection of bladder cancer.

Scand J Urol Nephrol 2011 Mar 22;45(2):113-21. Epub 2010 Nov 22.

Division of Urology, Department of Surgery, Faculty of Medicine, Kuwait University, Kuwait.

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http://dx.doi.org/10.3109/00365599.2010.533694DOI Listing
March 2011
8 Reads
5 Citations
1.062 Impact Factor

Raf kinase inhibitor protein RKIP enhances signaling by glycogen synthase kinase-3β.

Cancer Res 2011 Feb 8;71(4):1334-43. Epub 2011 Feb 8.

Department of Pathology, Faculty of Medicine, Health Sciences Center, Kuwait University, Safat, Kuwait, UK.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-3102DOI Listing
February 2011
20 Reads
36 Citations
9.330 Impact Factor

Whole Genome Amplification of DNA Extracted from FFPE Tissues

Bosso, M, Al-Mulla, F & Al-Mulla, F, 2011, , Humana Press, Totowa, NJ.

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January 2011
2 Reads

Microarray-Based CGH and Copy Number Analysis of FFPE Samples

Al-Mulla, F & Al-Mulla, F, 2011, , Humana Press, Totowa, NJ.

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January 2011
2 Reads

Analysis of DNA Methylation in FFPE Tissues Using the MethyLight Technology

Dallol, A, Al-Mulla, F, Al-Ali, W, Al-Shaibani, A & Al-Mulla, F, 2011, , Humana Press, Totowa, NJ.

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January 2011

Inflammation and apoptosis in aortic tissues of aged type II diabetes: amelioration with alpha-lipoic acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism.

Life Sci 2010 Jun 11;86(23-24):844-53. Epub 2010 Apr 11.

Department of Pharmacology & Toxicology, School of Medicine, Kuwait University, Kuwait.

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http://dx.doi.org/10.1016/j.lfs.2010.03.019DOI Listing
June 2010
7 Reads
11 Citations
2.702 Impact Factor

Expression of estrogen receptor alpha and estrogen receptor beta in fine needle aspirates of breast carcinoma.

Acta Cytol 2010 Jan-Feb;54(1):25-30

Cytology Unit and Cytology Laboratory, Department of Pathology, Faculty of Medicine, Kuwait University, Safat, Kuwait.

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http://dx.doi.org/10.1159/000324962DOI Listing
April 2010
11 Reads
1 Citation
1.562 Impact Factor

Impact of 226C>T MSH2 gene mutation on cancer phenotypes in two HNPCC-associated highly-consanguineous families from Kuwait: emphasis on premarital genetic testing.

Fam Cancer 2009 8;8(4):289-98. Epub 2009 Aug 8.

Kuwait Medical Genetics Centre, Maternity Hospital, 13059 Safat, Kuwait.

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http://dx.doi.org/10.1007/s10689-009-9275-3DOI Listing
January 2010
12 Reads
2 Citations
1.620 Impact Factor

Impact of 226C>T MSH2 gene mutation on cancer phenotypes in two HNPCC-associated highly-consanguineous families from Kuwait: emphasis on premarital genetic testing

Marafie, M, Al-Awadi, S, Al-Mosawi, F, Elshafey, A, Al-Ali, W & Al-Mulla, F, 2009, 'Impact of 226C>T MSH2 gene mutation on cancer phenotypes in two HNPCC-associated highly-consanguineous families from Kuwait: emphasis on premarital genetic testing', Familial Cancer, vol. 12, no. 3, pp. 30-298

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December 2009
2 Reads

Statistical Class Separation Using sEMG Features Towards Automated Muscle Fatigue Detection and Prediction

Al-Mulla, M, Sepulveda, F, Colley, M & Al-Mulla, F, 2009, 'Statistical Class Separation Using sEMG Features Towards Automated Muscle Fatigue Detection and Prediction', 2009 2nd International Congress on Image and Signal Processing, IEEE, Tianjin, China, pp. 1-5.

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October 2009
1 Read

Which obesity index best explains the link between adipokines, coronary heart disease risk and metabolic abnormalities in type 2 diabetes mellitus?

Med Princ Pract 2009 10;18(2):123-9. Epub 2009 Feb 10.

Department of Pathology, Faculty of Medicine, Kuwait University, Safat, Kuwait.

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http://dx.doi.org/10.1159/000189810DOI Listing
May 2009
9 Reads
7 Citations
1.113 Impact Factor

Planning the human variome project: the Spain report.

Authors:
Jim Kaput Richard G H Cotton Lauren Hardman Michael Watson Aida I Al Aqeel Jumana Y Al-Aama Fahd Al-Mulla Santos Alonso Stefan Aretz Arleen D Auerbach Bharati Bapat Inge T Bernstein Jong Bhak Stacey L Bleoo Helmut Blöcker Steven E Brenner John Burn Mariona Bustamante Rita Calzone Anne Cambon-Thomsen Michele Cargill Paola Carrera Lawrence Cavedon Yoon Shin Cho Yeun-Jun Chung Mireille Claustres Garry Cutting Raymond Dalgleish Johan T den Dunnen Carlos Díaz Steven Dobrowolski M Rosário N dos Santos Rosemary Ekong Simon B Flanagan Paul Flicek Yoichi Furukawa Maurizio Genuardi Ho Ghang Maria V Golubenko Marc S Greenblatt Ada Hamosh John M Hancock Ross Hardison Terence M Harrison Robert Hoffmann Rania Horaitis Heather J Howard Carol Isaacson Barash Neskuts Izagirre Jongsun Jung Toshio Kojima Sandrine Laradi Yeon-Su Lee Jong-Young Lee Vera L Gil-da-Silva-Lopes Finlay A Macrae Donna Maglott Makia J Marafie Steven G E Marsh Yoichi Matsubara Ludwine M Messiaen Gabriela Möslein Mihai G Netea Melissa L Norton Peter J Oefner William S Oetting James C O'Leary Ana Maria Oller de Ramirez Mark H Paalman Jillian Parboosingh George P Patrinos Giuditta Perozzi Ian R Phillips Sue Povey Suyash Prasad Ming Qi David J Quin Rajkumar S Ramesar C Sue Richards Judith Savige Dagmar G Scheible Rodney J Scott Daniela Seminara Elizabeth A Shephard Rolf H Sijmons Timothy D Smith María-Jesús Sobrido Toshihiro Tanaka Sean V Tavtigian Graham R Taylor Jon Teague Thoralf Töpel Mollie Ullman-Cullere Joji Utsunomiya Henk J van Kranen Mauno Vihinen Elizabeth Webb Thomas K Weber Meredith Yeager Young I Yeom Seon-Hee Yim Hyang-Sook Yoo

Hum Mutat 2009 Apr;30(4):496-510

Division of Personalised Nutrition and Medicine, FDA/National Center for Toxicological Research, Jefferson, Arkansas 72079, USA.

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http://doi.wiley.com/10.1002/humu.20972
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http://dx.doi.org/10.1002/humu.20972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879779PMC
April 2009
103 Reads
19 Citations
5.144 Impact Factor

Uses of microarray platforms in cancer: a correlative study between genomic copy number changes and their expression at mRNA and protein levels.

Methods Mol Biol 2007 ;382:77-95

Department of Pathology, Faculty of Medicine, Kuwait University, Safat.

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http://dx.doi.org/10.1007/978-1-59745-304-2_6DOI Listing
March 2008
15 Reads
2 Citations

Utilization of microarray platforms in clinical practice: an insight on the preparation and amplification of nucleic acids from frozen and fixed tissues.

Authors:
Fahd Al-Mulla

Methods Mol Biol 2007 ;382:115-36

Department of Pathology, Faculty of Medicine, Kuwait University, Safat.

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http://dx.doi.org/10.1007/978-1-59745-304-2_8DOI Listing
March 2008
9 Reads
1 Citation

Uses of Microarray Platforms in Cancer

Al-Mulla, F, Rampal, J, Walker, J & Al-Tamimi, R, 2007, , Humana Press, Totowa, NJ.

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2007
2 Reads

Clofibric acid, a peroxisome proliferator-activated receptor alpha ligand, inhibits growth of human ovarian cancer.

Mol Cancer Ther 2007 Apr;6(4):1379-86

Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Hirosaki, Amori, Japan.

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http://dx.doi.org/10.1158/1535-7163.MCT-06-0722DOI Listing
April 2007
35 Reads
33 Citations
5.683 Impact Factor

Depletion of the Ras association domain family 1, isoform A-associated novel microtubule-associated protein, C19ORF5/MAP1S, causes mitotic abnormalities.

Cancer Res 2007 Jan;67(2):492-500

Section of Medical and Molecular Genetics, Institute of Biomedical Research, University of Birmingham, Edgbaston, Birmingham, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3604DOI Listing
January 2007
6 Reads
18 Citations
9.330 Impact Factor

Raf kinase inhibitor protein expression in a survival analysis of colorectal cancer patients.

J Clin Oncol 2006 Dec;24(36):5672-9

Kuwait University, Faculty of Medicine, Safat, Kuwait.

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http://dx.doi.org/10.1200/JCO.2006.07.5499DOI Listing
December 2006
14 Reads
58 Citations
18.430 Impact Factor

Genetic profiling of stage I and II colorectal cancer may predict metastatic relapse.

Mod Pathol 2006 May;19(5):648-58

Molecular Pathology Laboratory, Department of Pathology, Faculty of Medicine, Kuwait University, Safat, Kuwait.

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http://dx.doi.org/10.1038/modpathol.3800564DOI Listing
May 2006
12 Reads
10 Citations
6.190 Impact Factor

Reduction of Raf-1 kinase inhibitor protein expression correlates with breast cancer metastasis.

Clin Cancer Res 2005 Oct;11(20):7392-7

Beatson Institute for Cancer Research, Signaling and Proteomics Laboratory, Glasgow, UK.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-0283DOI Listing
October 2005
6 Reads
66 Citations
8.722 Impact Factor

Oxidative stress — mediated alterations in glucose dynamics in a genetic animal model of type II diabetes

Bitar, M, AL-Saleh, E & AL-Mulla, F, 2005, 'Oxidative stress — mediated alterations in glucose dynamics in a genetic animal model of type II diabetes', Life Sciences, vol. 277, no. 20, pp. 50230-2573.

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October 2005
2 Reads

Oxidative stress--mediated alterations in glucose dynamics in a genetic animal model of type II diabetes.

Life Sci 2005 Sep;77(20):2552-73

Department of Pharmacology and Toxicology, Faculty of Medicine, Kuwait University, P.O. Box 24923, Safat, Kuwait, 13110.

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http://dx.doi.org/10.1016/j.lfs.2005.01.033DOI Listing
September 2005
16 Reads
12 Citations
2.702 Impact Factor

BRCA1 gene expression in breast cancer: a correlative study between real-time RT-PCR and immunohistochemistry.

J Histochem Cytochem 2005 May;53(5):621-9

Department of Pathology, Molecular Pathology Laboratory, Faculty of Medicine, Kuwait University, PO Box 24923, Safat 13110, Kuwait.

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http://dx.doi.org/10.1369/jhc.4A6544.2005DOI Listing
May 2005
18 Reads
12 Citations
1.960 Impact Factor

Nitric oxide dynamics and endothelial dysfunction in type II model of genetic diabetes

Bitar, M, Wahid, S, Mustafa, S, Al-Saleh, E, Dhaunsi, G & Al-Mulla, F, 2005, 'Nitric oxide dynamics and endothelial dysfunction in type II model of genetic diabetes', European Journal of Pharmacology, vol. 105, no. 11 Suppl 2, pp. 1631-64.

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March 2005
2 Reads

Nitric oxide dynamics and endothelial dysfunction in type II model of genetic diabetes.

Eur J Pharmacol 2005 Mar;511(1):53-64

Department of Pharmacology, Kuwait University, School of Medicine, Kuwait.

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http://dx.doi.org/10.1016/j.ejphar.2005.01.014DOI Listing
March 2005
22 Reads
36 Citations
2.532 Impact Factor

Comparison of two probe preparation methods using long oligonucleotide microarrays.

Biotechniques 2004 Nov;37(5):827-33

Kuwait University, Faculty of Medicine, Department of Pathology, Safat, Kuwait.

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http://dx.doi.org/10.2144/04375RR03DOI Listing
November 2004
10 Reads
1 Citation
2.950 Impact Factor

Glycolaldehyde induces apoptosis in a human breast cancer cell line.

Arch Biochem Biophys 2003 Sep;417(1):123-7

The Department of Biochemistry, Faculty of Medicine, Kuwait University, P.O. Box 24923, Safat 13110, Kuwait.

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http://dx.doi.org/10.1016/s0003-9861(03)00334-5DOI Listing
September 2003
6 Reads
2 Citations
3.020 Impact Factor

Mutant K-ras2 in serum.

Andreyev HJ, Benamouzig R, Beranek M, Clarke P, Cunningham D, Norman AR, Giaretti W, de Goeij AF, Iacopetta BJ, Jullian E, Krtolica K, Lee JQ, Wang ST, Lees N, Al-Mulla F, Muller O, Pauly M, Pricolo V, Russo A, Troungos C, Urosevic N, Ward R, Gut, 2003, vol. 52, no. 6, pp. 915-916

http://europepmc.org/abstract/med/12740358

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July 2003

Differences inin vitro invasive capacity induced by differences in Ki-Ras protein mutations

Al-Mulla, F & MacKenzie, E, 2001, 'Differences inin vitro invasive capacity induced by differences in Ki-Ras protein mutations', The Journal of Pathology, vol. 302, no. 5, pp. 157-556.

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2001

Carbonyl reductase: a novel metastasis-modulating function.

Cancer Res 2000 Mar;60(5):1173-6

The Beatson Institute for Cancer Research, Glasgow, Scotland.

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March 2000
5 Reads
9 Citations
9.330 Impact Factor

Top co-authors

Milad S Bitar
Milad S Bitar

Kuwait University

19
Rabeah Al-Temaimi
Rabeah Al-Temaimi

Faculty of Medicine, Kuwait University

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Amedeo Amedei
Amedeo Amedei

University of Florence

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Neetu Singh
Neetu Singh

King George's Medical University

11
Rabindra Roy
Rabindra Roy

Georgetown University Medical Center

11
Lorenzo Memeo
Lorenzo Memeo

Mediterranean Institute of Oncology

11
William H Bisson
William H Bisson

Oregon State University

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Jordan Woodrick
Jordan Woodrick

Georgetown University

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Stefano Forte
Stefano Forte

University of Catania

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Monica Vaccari
Monica Vaccari

National Cancer Institute

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