Fadi M Awadallah

Synthesis of some N-aroyl-2-oxindole benzenesulfonamide conjugates with carbonic anhydrase inhibitory activity.

Authors:

Riham F George Silvia Bua Claudiu T Supuran Fadi M Awadallah

Bioorg Chem 2020 03 29;96:103635. Epub 2020 Jan 29.

Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt. Electronic address:

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March 2020

Design and synthesis of novel PARP-1 inhibitors based on pyridopyridazinone scaffold.

Authors:

Ghada F Elmasry Enayat E Aly Fadi M Awadallah Samir M El-Moghazy

Bioorg Chem 2019 06 28;87:655-666. Epub 2019 Mar 28.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, El-Kasr El-Eini Street, P.O. Box 11562, Cairo, Egypt.

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June 2019

Inhibition studies on a panel of human carbonic anhydrases with N1-substituted secondary sulfonamides incorporating thiazolinone or imidazolone-indole tails.

Authors:

Fadi M Awadallah Silvia Bua Walaa R Mahmoud Hossam H Nada Alessio Nocentini Claudiu T Supuran

J Enzyme Inhib Med Chem 2018 Dec;33(1):629-638

b Department NEUROFARBA - Pharmaceutical and Nutraceutical Section , University of Firenze , Firenze , Italy.

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December 2018

Molecular docking simulation, synthesis and 3D pharmacophore studies of novel 2-substituted-5-nitro-benzimidazole derivatives as anticancer agents targeting VEGFR-2 and c-Met.

Authors:

Heba A Ibrahim Fadi M Awadallah Hanan M Refaat Kamilia M Amin

Bioorg Chem 2018 04 31;77:457-470. Epub 2018 Jan 31.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, 11562 Cairo, Egypt.

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April 2018

Design, synthesis and molecular modeling study for some new 2-substituted benzimidazoles as dual inhibitors for VEGFR-2 and c-Met.

Authors:

Heba A Ibrahim Fadi M Awadallah Hanan M Refaat Kamilia M Amin

Future Med Chem 2018 03 12;10(5):493-509. Epub 2018 Feb 12.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, 11562 Cairo, Egypt.

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March 2018

Design, synthesis and molecular docking of novel diarylcyclohexenone and diarylindazole derivatives as tubulin polymerization inhibitors.

Authors:

Riham I Ahmed Essam Eldin A Osman Fadi M Awadallah Samir M El-Moghazy

J Enzyme Inhib Med Chem 2017 Dec 24;32(1):176-188. Epub 2016 Oct 24.

b Department of Pharmaceutical Chemistry, Faculty of Pharmacy , Cairo University , Cairo , Egypt.

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December 2017

Identification of new potent phthalazine derivatives with VEGFR-2 and EGFR kinase inhibitory activity.

Authors:

Kamilia M Amin Flora F Barsoum Fadi M Awadallah Nehal E Mohamed

Eur J Med Chem 2016 Nov 22;123:191-201. Epub 2016 Jul 22.

Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Eini Street, 11562, Cairo, Egypt.

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November 2016

Synthesis, carbonic anhydrase inhibition and cytotoxic activity of novel chromone-based sulfonamide derivatives.

Authors:

Fadi M Awadallah Tamer A El-Waei Mona M Hanna Safinaz E Abbas Mariangela Ceruso Beyza Ecem Oz Ozen Ozensoy Guler Claudiu T Supuran

Eur J Med Chem 2015 15;96:425-35. Epub 2015 Apr 15.

University of Florence, Neurofarba Department, Via Ugo Schiff 6, Polo Scientifico, 50019, Sesto Fiorentino, Firenze, Italy. Electronic address:

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February 2016

Design and synthesis of potent 1,2,4-trisubstituted imidazolinone derivatives with dual p38αMAPK and ERK1/2 inhibitory activity.

Authors:

Fadi M Awadallah Sahar M Abou-Seri Mohamed M Abdulla Hanan H Georgey

Eur J Med Chem 2015 Apr 5;94:397-404. Epub 2015 Mar 5.

Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, 11562 Cairo, Egypt.

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April 2015

Synthesis and anticancer activity of some 8-substituted-7-methoxy-2H-chromen-2-one derivatives toward hepatocellular carcinoma HepG2 cells.

Authors:

Kamilia M Amin Sahar M Abou-Seri Fadi M Awadallah Amal A M Eissa Ghaneya S Hassan Mohamed M Abdulla

Eur J Med Chem 2015 Jan 15;90:221-31. Epub 2014 Nov 15.

Research Unit, Saco Pharm. Co., 6th October City, Egypt.

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January 2015

4-Substituted-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine derivatives: design, synthesis, antitumor and EGFR tyrosine kinase inhibitory activity.

Authors:

Safinaz E-S Abbas Enayat I Aly Fadi M Awadallah Walaa R Mahmoud

Chem Biol Drug Des 2015 May 14;85(5):608-22. Epub 2014 Nov 14.

Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Eini Street, 11562, Cairo, Egypt.

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May 2015

Synthesis of some dihydropyrimidine-based compounds bearing pyrazoline moiety and evaluation of their antiproliferative activity.

Authors:

Fadi M Awadallah Gary A Piazza Bernard D Gary Adam B Keeton Joshua C Canzoneri

Eur J Med Chem 2013 9;70:273-9. Epub 2013 Oct 9.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Kasr El-Eini, 11562 Cairo, Egypt. Electronic address:

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September 2014

Synthesis and biological evaluation of novel coumarin-pyrazoline hybrids endowed with phenylsulfonyl moiety as antitumor agents.

Authors:

Kamilia M Amin Amal A M Eissa Sahar M Abou-Seri Fadi M Awadallah Ghaneya S Hassan

Eur J Med Chem 2013 Feb 12;60:187-98. Epub 2012 Dec 12.

Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, PO Box 11562, Cairo, Egypt.

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February 2013

New quinazolinone-pyrimidine hybrids: synthesis, anti-inflammatory, and ulcerogenicity studies.

Authors:

Safinaz E Abbas Fadi M Awadallah Nashwa A Ibrahin Eman G Said Gihan M Kamel

Eur J Med Chem 2012 Jul 9;53:141-9. Epub 2012 Apr 9.

Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, 11562 Kasr El-Eini, Cairo, Egypt.

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July 2012

Synthesis, vasorelaxant activity, and molecular modeling study of some new phthalazine derivatives.

Authors:

Fadi M Awadallah Wafaa I el-Eraky Dalia O Saleh

Eur J Med Chem 2012 Jun 3;52:14-21. Epub 2012 Mar 3.

Pharmaceutical Chemistry department, Faculty of Pharmacy, Cairo University, 11562 Cairo, Egypt.

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June 2012

Synthesis, anti-inflammatory and ulcerogenicity studies of some substituted pyrimido[1,6-a]azepine derivatives.

Authors:

Nehad A El-Sayed Fadi M Awadallah Nashwa A Ibrahim Mohammed T El-Saadi

Eur J Med Chem 2010 Jul 14;45(7):3147-54. Epub 2010 Apr 14.

Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr-El-Eini street 11562 Cairo, Egypt.

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July 2010

Novel substituted and fused pyrrolizine derivatives: synthesis, anti-inflammatory and ulcerogenecity studies.

Authors:

Safinaz E Abbas Fadi M Awadallah Nashwa A Ibrahim Ahmed M Gouda

Eur J Med Chem 2010 Feb 25;45(2):482-91. Epub 2009 Oct 25.

Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Eini street 11562 Cairo, Egypt.

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February 2010

Synthesis of novel lactam derivatives and their evaluation as ligands for the dopamine receptors, leading to a D(4)-selective ligand.

Authors:

Fadi M Awadallah Franziska Müller Jochen Lehmann Ashraf H Abadi

Bioorg Med Chem 2007 Sep 7;15(17):5811-8. Epub 2007 Jun 7.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.

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September 2007

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