Publications by authors named "Facundo Jorro"

5 Publications

  • Page 1 of 1

Theory-driven, rapid formative research on quality improvement intervention for critical care of patients with COVID-19 in Argentina.

Glob Qual Nurs Res 2021 Jan-Dec;8:23333936211015660. Epub 2021 May 12.

Institute for Clinical Effectiveness and Health Policy, (IECS), Buenos Aires, Argentina.

The challenges of implementing interventions in healthcare settings have been more apparent during the COVID-19 pandemic. This pre-implementation evaluation used a rapid qualitative approach to explore barriers and facilitators to an intervention in intensive care units in Argentina, aimed to promote the use of personal protection equipment, provide emotional support for professionals, and achieve patient flow goals. Data were collected using semi-structured interviews with health professionals of 15 public hospitals in Argentina. Normalization Process Theory was used to guide content analysis of the data. Participants identified potential barriers such as the incorporation of non-specialist staff, shortage of resources, lack of communication between groups and shifts. Potential facilitators were also identified: regular feedback and communication related to implementation, adequate training for new and non-specialist staff, and incentives (e.g., scholarships). The immediacy of the pandemic demanded rapid qualitative research, sharing actionable findings in real time.
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http://dx.doi.org/10.1177/23333936211015660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120599PMC
May 2021

[Patient safety and the international goals: Consensus document].

Arch Argent Pediatr 2019 12;117(6):S277-S309

Subcomisión de Calidad de Atención y Seguridad del Paciente.

Patient safety is one of the dimensions of care. Medical advances have made assistance processes more and more complex, and there is usually a combination of circumstances that converge for errors to occur. Adverse events constitute a serious public health problem, causing damages of varying degrees to the patient and his family, which also leads to an increase in the cost of the care process and hospital stay. Most of the adverse events occur in hospitals because their complexity is subject to a greater risk associated with care. That is why we present this consensus with the aim of offering tools whose implementation can contribute to provide a safer healthcare.
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http://dx.doi.org/10.5546/aap.2019.S277DOI Listing
December 2019

[Pediatric emergency medicine specialty: Welcome!]

Arch Argent Pediatr 2018 08;116(4):298-300

Comité de Emergencias y Cuidados Críticos, Sociedad Argentina de Pediatría.

Pediatric Emergency Medicine has developed around the world as a subspecialty of pediatrics. There is plenty of data reflecting a growing need for its services. The subspecialty was initiated in the United States and Argentina, together with other Latin American countries, followed the same path. Nevertheless, there is yet much to be done. It is necessary to strengthen its promotion and to stimulate research and teaching activities in order to continue improving the quality of care delivered to the pediatric population, their families and society as a whole.
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http://dx.doi.org/10.5546/aap.2018.298DOI Listing
August 2018

Impact of a program aimed at reducing catheter-related infections implemented in nine pediatric intensive care units in Argentina.

Arch Argent Pediatr 2018 Apr;116(2):93-97

Hospital de Pediatría "J. P. Garrahan", Ciudad Autónoma de Buenos Aires.

Introduction: Catheter-related infections (CRIs) cause a high level of morbidity and mortality with the increasing use of hospital resources.

Objective: To describe the outcomes of a program implemented to reduce the rate of CRIs in pediatric intensive care units in Argentina.

Population And Methods: Collaborative, multi center, clinical-epidemiological, quasiexperimental, before-and-after intervention study. Children who had a central venous catheter during hospitalization in 9 pediatric intensive care units in the Autonomous City of Buenos Aires, Greater Buenos Aires, and other provinces between June 2011 and April 2012 were included. A bundle of measures based on health care staff training on catheter insertion, hand hygiene, and checklists was put into practice and implemented measures were monitored. The number and annual rate of CRIs and the rate of central venous catheter use before and after the program implementation were compared (Stata 8.0).

Results: The total number of CRIs was 117 and 74 before and after the intervention, respectively. The rate of CRIs was 8.6/1000 days of central venous catheter use and 5.8/1000 days before and after the intervention, respectively; RR: 0.82 (95% confidence interval: 0.68-0.98), p= 0.015. The rate of central venous catheter use decreased from 54% to 49%, a non-significant difference.

Conclusions: The program achieved a significant reduction in CRI rates. Based on the program, CRI surveillance was implemented in all participating pediatric intensive care units. Training and continuous surveillance are necessary to maintain and improve the outcomes accomplished with the program.
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http://dx.doi.org/10.5546/aap.2018.eng.93DOI Listing
April 2018

Heat shock proteins HSP27 and HSP70 in unilateral obstructed kidneys.

Pediatr Nephrol 2003 Jun 16;18(6):527-35. Epub 2003 Apr 16.

Department of Physiopathology, Medical School, National University of Cuyo, Centro Universitario 5500, Mendoza, Argentina.

Unilateral ureteropelvic junction obstruction (UPJO), a condition involving injury to the kidney, leads to vasoconstriction, macrophage infiltration, oxidative stress, and tubulointerstitial fibrosis. In the present study we analyzed in 22 children, the impact of UPJO on expression of HSP27 and HSP70 and related the changes to renal function and duration of obstruction. Kidney function was evaluated, and renal biopsies were obtained for immunohistochemical and western blot analyses at the time of surgery. Kidney tissue from 5 children of similar age, removed because of various malignancies, was used as control. Increased HSP27, with an expression pattern related to the duration of the obstruction, was noted in proximal tubules (PTs), cortical collecting ducts (CCDs), and medullary collecting ducts. Strong HSP27 staining in cytoplasm and nuclei of these segments appeared in children with kidney obstruction for 2.1+/-0.41 years. HSP70 showed a close spatial expression pattern with that of HSP27. The increased staining of HSP70 in PTs and CCDs was related to the decreased glomerular filtration rate. The constitutive/cognate form of HSP70 (HSC72) was absent. These results support the concept that HSP27 and HSP70 are involved in the adaptive response of the human kidney to congenital UPJO.
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http://dx.doi.org/10.1007/s00467-003-1096-2DOI Listing
June 2003
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