Fabrizio Montecucco

Fabrizio Montecucco

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Fabrizio Montecucco

Publications by authors named "Fabrizio Montecucco"

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Inflammation and pericarditis: Are neutrophils actors behind the scenes?

J Cell Physiol 2019 May 11;234(5):5390-5398. Epub 2018 Nov 11.

Department of Internal Medicine, First Clinic of Internal Medicine, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1002/jcp.27436DOI Listing
May 2019

Serum osteopontin negatively impacts on intima-media thickness in patients with systemic lupus erythematosus.

Eur J Clin Invest 2019 May 3;49(5):e13089. Epub 2019 Mar 3.

IRCCS Ospedale Policlinico San Martino Genoa - Italian Cardiovascolar Network, Genoa, Italy.

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http://dx.doi.org/10.1111/eci.13089DOI Listing
May 2019

The STOP DIABETES study: when prevention works.

Acta Diabetol 2019 May 2;56(5):501-504. Epub 2019 Mar 2.

First Clinic of Internal Medicine, Department of Internal Medicine and Centre of Excellence for Biomedical Research (CEBR), University of Genoa, 6 viale Benedetto XV, 16132, Genoa, Italy.

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http://dx.doi.org/10.1007/s00592-019-01309-6DOI Listing
May 2019

Impact of different ectopic fat depots on cardiovascular and metabolic diseases.

J Cell Physiol 2019 May 20. Epub 2019 May 20.

Department of Internal Medicine, First Clinic of Internal Medicine, University of Genoa, Genoa, Italy.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/jcp.28821
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http://dx.doi.org/10.1002/jcp.28821DOI Listing
May 2019

Radiologic Cerebral Reperfusion at 24 h Predicts Good Clinical Outcome.

Transl Stroke Res 2019 04 14;10(2):178-188. Epub 2018 Jun 14.

Struttura Organizzativa Dipartimentale di Neuroradiologia, Dipartimento di Scienze Biomediche, Sperimentali e Cliniche, Università degli Studi di Firenze, Azienda Ospedaliero-Universitaria Careggi, 3 Largo Brambilla, 50134, Florence, Italy.

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http://dx.doi.org/10.1007/s12975-018-0637-8DOI Listing
April 2019

The need of developing selective prediction models in elderly patients with heart failure.

Int J Clin Pract 2019 Apr 22:e13354. Epub 2019 Apr 22.

IRCCS Ospedale Policlinico San Martino Genoa, 10 largo Benzi, 16132, Genoa, Italy.

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http://dx.doi.org/10.1111/ijcp.13354DOI Listing
April 2019

Epicardial adipose tissue and cardiovascular diseases.

Int J Cardiol 2019 Mar 1;278:254-260. Epub 2018 Oct 1.

Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01675273183368
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http://dx.doi.org/10.1016/j.ijcard.2018.09.089DOI Listing
March 2019

Update on pathological platelet activation in coronary thrombosis.

J Cell Physiol 2019 Mar 14;234(3):2121-2133. Epub 2018 Oct 14.

Department of Internal Medicine, First Clinic of Internal Medicine, University of Genoa, Genoa, Italy.

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http://doi.wiley.com/10.1002/jcp.27575
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http://dx.doi.org/10.1002/jcp.27575DOI Listing
March 2019

Novel findings in neutrophil biology and their impact on cardiovascular disease.

Cardiovasc Res 2019 Mar 27. Epub 2019 Mar 27.

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy.

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https://academic.oup.com/cardiovascres/advance-article/doi/1
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http://dx.doi.org/10.1093/cvr/cvz084DOI Listing
March 2019

Predictors of cardiovascular outcome and rehospitalization in elderly patients with heart failure.

Eur J Clin Invest 2019 Feb 16;49(2):e13044. Epub 2018 Nov 16.

IRCCS Ospedale Policlinico San Martino Genoa, Genoa, Italy.

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http://dx.doi.org/10.1111/eci.13044DOI Listing
February 2019

Pericardial adipose tissue and cardiovascular diseases: New insights from basic research.

Eur J Clin Invest 2019 Feb 13;49(2):e13052. Epub 2018 Dec 13.

First Clinic of Internal Medicine, Department of Internal Medicine, Centre of Excellence for Biomedical Research (CEBR), University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1111/eci.13052DOI Listing
February 2019

New insights into the role of DNA methylation in cardiovascular disease.

Eur J Clin Invest 2019 Feb 13;49(2):e13051. Epub 2018 Dec 13.

First Clinic of Internal Medicine, Department of Internal Medicine and Centre of Excellence for Biomedical Research (CEBR), University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1111/eci.13051DOI Listing
February 2019

Targeting mitochondria to oppose the progression of nonalcoholic fatty liver disease.

Biochem Pharmacol 2019 Feb 30;160:34-45. Epub 2018 Nov 30.

Clinica Medica "A. Murri", Department of Biomedical Sciences and Human Oncology, University of Bari Medical School, Bari, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2018.11.020DOI Listing
February 2019

Promising findings on the role of endothelin-1 and related peptides in primary cardiovascular prevention.

Trends Cardiovasc Med 2019 Feb 19. Epub 2019 Feb 19.

Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran; Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.tcm.2019.02.006DOI Listing
February 2019

Reply to "PCSK9: Entering a new era of cardiovascular risk prediction".

Int J Cardiol 2019 01 7;274:356. Epub 2018 Aug 7.

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy; IRCCS AOU San Martino - IST, Genova, 10 Largo Benzi, 16132 Genoa, Italy; Centre of Excellence for Biomedical Research (CEBR), University of Genoa, 9 viale Benedetto XV, 16132 Genoa, Italy.

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http://dx.doi.org/10.1016/j.ijcard.2018.06.084DOI Listing
January 2019

Comment on "Characterization of circulating leukocytes and correlation of leukocyte subsets with metabolic parameters 1 and 5 years after diabetes diagnosis".

Acta Diabetol 2019 Jan 18;56(1):127-128. Epub 2018 Sep 18.

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132, Genoa, Italy.

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http://dx.doi.org/10.1007/s00592-018-1229-5DOI Listing
January 2019

Resistin exerts a beneficial role in atherosclerotic plaque inflammation by inhibiting neutrophil migration.

Int J Cardiol 2018 Dec 24;272:13-19. Epub 2018 Jul 24.

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 Viale Benedetto XV, 16132 Genoa, Italy; Ospedale Policlinico San Martino, 10 Largo Benzi, 16132 Genoa, Italy; Centre of Excellence for Biomedical Research (CEBR), University of Genoa, 9 Viale Benedetto XV, 16132 Genoa, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2018.07.112DOI Listing
December 2018

Thrombin induces protease-activated receptor 1 signaling and activation of human atrial fibroblasts and dabigatran prevents these effects.

Int J Cardiol 2018 Nov 24;271:219-227. Epub 2018 May 24.

Laboratory of Cardiovascular Biology, Department of Internal Medicine, University of Genova, Genova, Italy; Cardiovascular Disease Unit, IRCCS Ospedale Policlinico San Martino, Genova, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2018.05.033DOI Listing
November 2018

Post-ischaemic administration of the murine Canakinumab-surrogate antibody improves outcome in experimental stroke.

Eur Heart J 2018 Oct;39(38):3511-3517

Center for Molecular Cardiology, Schlieren Campus, University of Zurich, Wagistrasse 12, Schlieren, Switzerland.

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http://dx.doi.org/10.1093/eurheartj/ehy286DOI Listing
October 2018

Aspirin in primary prevention for patients with diabetes: Still a matter of debate.

Eur J Clin Invest 2018 Oct 1;48(10):e13001. Epub 2018 Aug 1.

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1111/eci.13001DOI Listing
October 2018

Reduction in TIMP-2 serum levels predicts remission of inflammatory bowel diseases.

Eur J Clin Invest 2018 Oct 6;48(10):e13002. Epub 2018 Aug 6.

Division of Gastroenterology Department of Internal Medicine, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1111/eci.13002DOI Listing
October 2018

Novel cardiovascular risk biomarkers in carotid atherogenesis.

Biomark Med 2018 10 19;12(10):1065-1067. Epub 2018 Sep 19.

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy.

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http://dx.doi.org/10.2217/bmm-2018-0198DOI Listing
October 2018

T-cells in myocardial infarction: Culprit instigators or mere effectors?

World J Cardiol 2018 Oct;10(10):123-126

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, Genoa 16132, Italy.

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http://www.wjgnet.com/1949-8462/full/v10/i10/123.htm
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http://dx.doi.org/10.4330/wjc.v10.i10.123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205846PMC
October 2018

Pre-surgery age-adjusted Charlson Comorbidity Index is associated with worse outcomes in acute cholecystitis.

Dig Liver Dis 2018 Oct 11. Epub 2018 Oct 11.

Surgery Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

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http://dx.doi.org/10.1016/j.dld.2018.10.002DOI Listing
October 2018

Impact of fibrates on circulating cystatin C levels: a systematic review and meta-analysis of clinical trials.

Ann Med 2018 Sep 7;50(6):485-493. Epub 2018 Sep 7.

m Anti-Doping Laboratory Qatar , Life Sciences & Research Division , Doha , Qatar.

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http://dx.doi.org/10.1080/07853890.2018.1495338DOI Listing
September 2018

Reply to "Osteopontin inhibits macrophage cholesterol efflux via NF-κB/ABCA1 pathway".

Int J Cardiol 2018 09;267:195

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy; Ospedale Policlinico San Martino, 10 Largo Benzi, 16132 Genoa, Italy; Centre of Excellence for Biomedical Research (CEBR), University of Genoa, 9 viale Benedetto XV, 16132 Genoa, Italy.

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http://dx.doi.org/10.1016/j.ijcard.2018.05.105DOI Listing
September 2018

Serum cardiovascular risk biomarkers in pre-pubertal obese children.

Eur J Clin Invest 2018 Sep 6;48(9):e12995. Epub 2018 Aug 6.

Paediatric Cardiology Unit, Service of Paediatric Specialties, Department of Child and Adolescent, University Hospitals of Geneva and University of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1111/eci.12995DOI Listing
September 2018

Atherosclerosis in Rheumatoid Arthritis: Promoters and Opponents.

Clin Rev Allergy Immunol 2018 Sep 26. Epub 2018 Sep 26.

IRCCS Ospedale Policlinico San Martino Genoa, 10 Largo Benzi, 16132, Genoa, Italy.

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http://dx.doi.org/10.1007/s12016-018-8714-zDOI Listing
September 2018

Oxidative burden in familial hypercholesterolemia.

J Cell Physiol 2018 Aug 7;233(8):5716-5725. Epub 2018 Mar 7.

Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.

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http://dx.doi.org/10.1002/jcp.26466DOI Listing
August 2018

Ischemic stroke across sexes: What is the status quo?

Front Neuroendocrinol 2018 07 16;50:3-17. Epub 2018 May 16.

Center for Molecular Cardiology, University of Zürich, Wagistrasse 12, CH-8952 Schlieren, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.yfrne.2018.05.001DOI Listing
July 2018

Serum PCSK9 levels predict the occurrence of acute coronary syndromes in patients with severe carotid artery stenosis.

Int J Cardiol 2018 07;263:138-141

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy; Ospedale Policlinico San Martino, 10 Largo Benzi, 16132 Genoa, Italy; Centre of Excellence for Biomedical Research (CEBR), University of Genoa, 9 viale Benedetto XV, 16132 Genoa, Italy.

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http://dx.doi.org/10.1016/j.ijcard.2018.03.081DOI Listing
July 2018

Steroid-induced hyperglycemia: An underdiagnosed problem or clinical inertia? A narrative review.

Diabetes Res Clin Pract 2018 May 9;139:203-220. Epub 2018 Mar 9.

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy; Ospedale Policlinico San Martino, 10 Largo Benzi, 16132 Genoa, Italy; Centre of Excellence for Biomedical Research (CEBR), University of Genoa, 9 viale Benedetto XV, 16132 Genoa, Italy.

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http://dx.doi.org/10.1016/j.diabres.2018.03.006DOI Listing
May 2018

Ischemic stroke across sexes: what is the status quo?

Front Neuroendocrinol 2018 May 12. Epub 2018 May 12.

Center for Molecular Cardiology, University of Zürich, Wagistrasse 12, CH-8952 Schlieren, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.yfrne.2018.04.001DOI Listing
May 2018

Levels of serum uric acid at admission for hypoglycaemia predict 1-year mortality.

Acta Diabetol 2018 Apr 11;55(4):323-330. Epub 2018 Jan 11.

Diabetology Unit, Department of Internal Medicine, University of Genoa, 6 Viale Benedetto XV, 16132, Genoa, Italy.

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http://dx.doi.org/10.1007/s00592-017-1094-7DOI Listing
April 2018

Induction of cell killing and autophagy by amphiphilic pyrrolidine derivatives on human pancreatic cancer cells.

Eur J Med Chem 2018 Apr 2;150:457-478. Epub 2018 Mar 2.

Laboratory of Glycochemistry and Asymmetric Synthesis, Swiss Federal Institute of Technology (EPFL), Batochime, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.ejmech.2018.02.086DOI Listing
April 2018

Short-term effect of rosuvastatin treatment on arterial stiffness in individuals with newly-diagnosed heterozygous familial hypercholesterolemia.

Int J Cardiol 2018 Mar 27;255:215-220. Epub 2017 Dec 27.

First Clinic of Internal Medicine, Department of Internal Medicine, Ospedale Policlinico San Martino, Genova, University of Genova, Largo Benzi 10, 16132 Genova, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.12.051DOI Listing
March 2018

Serum adiponectin levels predict acute coronary syndrome (ACS) in patients with severe carotid stenosis.

Vascul Pharmacol 2018 03 2;102:37-43. Epub 2018 Jan 2.

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy; Ospedale Policlinico San Martino, 10 Largo Benzi, 16132 Genoa, Italy; Centre of Excellence for Biomedical Research (CEBR), University of Genoa, 9 viale Benedetto XV, 16132 Genoa, Italy.

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http://dx.doi.org/10.1016/j.vph.2017.12.066DOI Listing
March 2018

Serum levels of osteopontin predict major adverse cardiovascular events in patients with severe carotid artery stenosis.

Int J Cardiol 2018 Mar 5;255:195-199. Epub 2018 Jan 5.

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa School of Medicine, 6 viale Benedetto XV, 13132 Genoa, Italy; Ospedale Policlinico San Martino, 10 Largo Benzi, 16132 Genoa, Italy; Centre of Excellence for Biomedical Research (CEBR), University of Genoa, 9 viale Benedetto XV, 16132 Genoa, Italy.

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http://dx.doi.org/10.1016/j.ijcard.2018.01.008DOI Listing
March 2018

Apelin-13 treatment enhances the stability of atherosclerotic plaques.

Eur J Clin Invest 2018 Mar 5;48(3). Epub 2018 Feb 5.

Department of Physiology and Biophysics, Federal University of Minas Gerais, Belo Horizonte, Brazil.

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http://dx.doi.org/10.1111/eci.12891DOI Listing
March 2018

The quest for endothelial atypical cannabinoid receptor: BK channels act as cellular sensors for cannabinoids in in vitro and in situ endothelial cells.

Vascul Pharmacol 2018 03 31;102:44-55. Epub 2018 Jan 31.

Division of Cardiology, Foundation for Medical Researches, Department of Internal Medicine, University of Geneva, Av. de la Roseraie 64, CH 1211, Geneva 4, Switzerland.

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http://dx.doi.org/10.1016/j.vph.2018.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481560PMC
March 2018

Obesity phenotypes and their paradoxical association with cardiovascular diseases.

Eur J Intern Med 2018 02;48:6-17

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy; Ospedale Policlinico San Martino, Istituto di Ricovero e Cura a Carattere Scientifico per l'Oncologia, 10 Largo Benzi, 16132 Genoa, Italy; Centre of Excellence for Biomedical Research (CEBR), University of Genoa, 9 viale Benedetto XV, 16132 Genoa, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejim.2017.10.020DOI Listing
February 2018

A translational evidence for cholesteryl ester transfer protein modulation by glucocorticoids: A time for reflection.

Eur J Clin Invest 2018 02 30;48(2). Epub 2017 Nov 30.

Department of Internal Medicine, First Clinic of Internal Medicine, University of Genoa, Genoa, Italy.

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http://doi.wiley.com/10.1111/eci.12856
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http://dx.doi.org/10.1111/eci.12856DOI Listing
February 2018

Anti-apolipoprotein A-1 autoantibodies are associated with immunodeficiency and systemic inflammation in HIV patients.

J Infect 2018 Feb 14;76(2):186-195. Epub 2017 Dec 14.

Division of Laboratory Medicine, Department of Genetics and Laboratory Medicine, Geneva University Hospitals, 4 rue Gabrielle Perret-Gentil, 1205 Geneva, Switzerland; Clinical Chemistry and Proteomic Group, Department of Human Protein Sciences, University of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1016/j.jinf.2017.11.008DOI Listing
February 2018

Ca-dependent potassium channels and cannabinoid signaling in the endothelium of apolipoprotein E knockout mice before plaque formation.

J Mol Cell Cardiol 2018 02 3;115:54-63. Epub 2018 Jan 3.

Division of Cardiology, Foundation for Medical Researches, Department of Internal Medicine, University of Geneva, Av. de la Roseraie 64, CH -1211 Geneva, 4, Switzerland.

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http://dx.doi.org/10.1016/j.yjmcc.2018.01.002DOI Listing
February 2018

Surgery to Treat Symptomatic Mobile Cecum Syndrome Is Safe and Associated with Good Recovery Outcomes.

Case Rep Gastrointest Med 2018 8;2018:4718406. Epub 2018 Feb 8.

Dipartimento di Scienze Chirurgiche e Diagnostiche Integrate (DISC), Università degli Studi di Genova, 8 Largo Benzi, 16132 Genoa, Italy.

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https://www.hindawi.com/journals/crigm/2018/4718406/
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http://dx.doi.org/10.1155/2018/4718406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822757PMC
February 2018

A critical role of pentraxin 3 in severe sepsis and septic shock.

Eur J Clin Invest 2018 Jan 28;48(1). Epub 2017 Nov 28.

Division of Cardiology, Department of Medical Specialties, Geneva University Hospitals, Geneva, Switzerland.

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http://dx.doi.org/10.1111/eci.12855DOI Listing
January 2018

The Pathophysiological Role of Neutrophil Extracellular Traps in Inflammatory Diseases.

Thromb Haemost 2018 01 5;118(1):6-27. Epub 2018 Jan 5.

Department of Internal Medicine, First Clinic of Internal Medicine, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1160/TH17-09-0630DOI Listing
January 2018

Targeting Inflammation in Primary Cardiovascular Prevention.

Curr Pharm Des 2016 ;22(37):5662-5675

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy.

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December 2017

Detection of the "Crossed Aorta Sign" during Echocardiography before Angiography.

Case Rep Cardiol 2017 14;2017:9249821. Epub 2017 Dec 14.

Division of Cardiology, Department of Internal Medicine, University of Genoa, 6 Viale Benedetto XV, 16132 Genoa, Italy.

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http://dx.doi.org/10.1155/2017/9249821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745736PMC
December 2017

4D cardiac imaging at clinical 3.0T provides accurate assessment of murine myocardial function and viability.

Magn Reson Imaging 2017 12 5;44:46-54. Epub 2017 Aug 5.

Division of Radiology, Department of Radiology and Medical Informatics, Geneva University Hospital and Faculty of Medicine, University of Geneva, 4 rue Gabrielle-Perret-Gentil, 1205 Geneva, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0730725X173014
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http://dx.doi.org/10.1016/j.mri.2017.07.024DOI Listing
December 2017

Combining echo and natriuretic peptides to guide heart failure care in the outpatient setting: A position paper.

Eur J Clin Invest 2017 Dec 14;47(12). Epub 2017 Nov 14.

Cardiovascular and Thoracic Department, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1111/eci.12846DOI Listing
December 2017

Update on the role of Pentraxin 3 in atherosclerosis and cardiovascular diseases.

Vascul Pharmacol 2017 12 16;99:1-12. Epub 2017 Oct 16.

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.vph.2017.10.003DOI Listing
December 2017

Impact of CD14 Polymorphisms on Anti-Apolipoprotein A-1 IgG-Related Coronary Artery Disease Prediction in the General Population.

Arterioscler Thromb Vasc Biol 2017 12 26;37(12):2342-2349. Epub 2017 Oct 26.

From the Department of Internal Medicine, University Hospital of Lausanne, Switzerland (P.A., P.M.-V., G.W., P.V.); Division of Laboratory Medicine, Department of Genetics and Laboratory Medicine, Geneva University Hospitals, Switzerland (J.V., S.P., N.S., F. Montecucco, N.V.); Department of Human Protein Sciences, Faculty of Medicine, (J.V., S.P., N.S., N.V.), Department of Pathology and Immunology, Faculty of Medicine (O.H.), and Division of Cardiology, Foundation for Medical Researches, Department of Medical Specialties (F. Montecucco, F. Mach), University of Geneva, Switzerland; First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, Italy (F. Montecucco); Institute of Social and Preventive Medicine, University Hospital of Lausanne, Switzerland (Z.K.); and Swiss Institute of Bioinformatics, Lausanne, Switzerland (Z.K.).

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http://dx.doi.org/10.1161/ATVBAHA.117.309602DOI Listing
December 2017

Sepsis by in an Elderly Immunocompetent Patient after a Cat Bite.

Case Rep Infect Dis 2017 26;2017:2527980. Epub 2017 Nov 26.

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 Viale Benedetto XV, 16132 Genoa, Italy.

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http://dx.doi.org/10.1155/2017/2527980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727562PMC
November 2017

Early reduction of matrix metalloproteinase-8 serum levels is associated with leptin drop and predicts diabetes remission after bariatric surgery.

Int J Cardiol 2017 Oct 13;245:257-262. Epub 2017 Jul 13.

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy; First Clinic of Internal Medicine, IRCCS AOU San Martino - IST, Genoa, 10 Largo Benzi, 16132 Genoa, Italy; Centre of Excellence for Biomedical Research (CEBR), University of Genoa, 9 viale Benedetto XV, 16132 Genoa, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.07.044DOI Listing
October 2017

Glucose-targeted therapy for subjects with type 2 diabetes mellitus: primum non nocere.

Eur J Clin Invest 2017 10 31;47(10):691-693. Epub 2017 Aug 31.

Diabetes Unit, Department of Internal Medicine, University of Genova and Ospedale Policlinico S. Martino, Genova, Italy.

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http://dx.doi.org/10.1111/eci.12791DOI Listing
October 2017

Monocyte count at onset predicts poststroke outcomes during a 90-day follow-up.

Eur J Clin Invest 2017 Oct 2;47(10):702-710. Epub 2017 Sep 2.

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1111/eci.12795DOI Listing
October 2017

The need of identifying circulating biomarkers of coronary dysfunction.

Int J Cardiol 2017 09;242:27

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy; IRCCS AOU San Martino - IST, Genova, 10 Largo Benzi, 16132 Genoa, Italy; Centre of Excellence for Biomedical Research (CEBR), University of Genoa, 9 viale Benedetto XV, 16132 Genoa, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.05.015DOI Listing
September 2017

Treatment with Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors to Reduce Cardiovascular Inflammation and Outcomes.

Curr Med Chem 2017 ;24(14):1403-1416

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa. Italy.

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http://dx.doi.org/10.2174/0929867324666170303123734DOI Listing
August 2017

Direct activation of Ca and voltage-gated potassium channels of large conductance by anandamide in endothelial cells does not support the presence of endothelial atypical cannabinoid receptor.

Eur J Pharmacol 2017 Jun 19;805:14-24. Epub 2017 Mar 19.

Division of Cardiology, Foundation for Medical Researches, Department of Internal Medicine, University of Geneva, Av. de la Roseraie 64, CH-1211 Geneva 4, Switzerland.

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http://dx.doi.org/10.1016/j.ejphar.2017.03.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520242PMC
June 2017

The Role and Potential Therapeutic Implications of the Fibroblast Growth Factors in Energy Balance and Type 2 Diabetes.

Curr Diab Rep 2017 06;17(6):43

Metabolic Research Laboratory, Clínica Universidad de Navarra, Avda. Pío XII, 36, 31008, Pamplona, Spain.

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http://dx.doi.org/10.1007/s11892-017-0866-3DOI Listing
June 2017

Erratum to: The Role of Adipocytokines in Coronary Atherosclerosis.

Curr Atheroscler Rep 2017 05;19(5):21

Department of Internal Medicine, University of Genoa, 6 Viale Benedetto XV, 16132, Genoa, Italy.

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http://dx.doi.org/10.1007/s11883-017-0657-yDOI Listing
May 2017

Impact of Red Wine Consumption on Cardiovascular Health.

Curr Med Chem 2017 May 17. Epub 2017 May 17.

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa. Italy.

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http://dx.doi.org/10.2174/0929867324666170518100606DOI Listing
May 2017

Biophysical aspects and novel treatments of atrial fibrillation.

Minerva Cardioangiol 2017 Apr 19;65(2):157-172. Epub 2016 Jul 19.

Department of Cardiology, IRCCS S. Martino Hospital, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.23736/S0026-4725.16.04167-0DOI Listing
April 2017

Plasma palmitoylethanolamide (PEA) as a potential biomarker for impaired coronary function.

Int J Cardiol 2017 Mar 13;231:1-5. Epub 2016 Dec 13.

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy; IRCCS AOU San Martino-IST, Genova, largo Benzi 10, 16143 Genoa, Italy; Centre of Excellence for Biomedical Research (CEBR), University of Genoa, 9 viale Benedetto XV, 16132 Genoa, Italy.. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.12.023DOI Listing
March 2017

The Role of Inflammation in Cardiovascular Outcome.

Curr Atheroscler Rep 2017 Mar;19(3):11

First Clinic of Internal Medicine, Department of Internal Medicine and Medical Specialties, University of Genoa, 6 viale Benedetto XV, 16132, Genoa, Italy.

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http://dx.doi.org/10.1007/s11883-017-0646-1DOI Listing
March 2017

Coronary stenting: A matter of revascularization.

World J Cardiol 2017 Mar;9(3):207-211

Aldo Bonaventura, Fabrizio Montecucco, Luca Liberale, First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa School of Medicine and IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, 16132 Genoa, Italy.

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http://dx.doi.org/10.4330/wjc.v9.i3.207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368670PMC
March 2017

Toll-like receptor 4 signalling mediates inflammation in skeletal muscle of patients with chronic kidney disease.

J Cachexia Sarcopenia Muscle 2017 Feb 18;8(1):131-144. Epub 2016 Oct 18.

Department of Internal Medicine, Nephrology Division and First Clinic of Internal Medicine, University of Genova and IRCCS AOU San Martino-IST, and Ospedale Santa ChiaraI, Trento, Italy.

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http://dx.doi.org/10.1002/jcsm.12129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326826PMC
February 2017

Alamandine abrogates neutrophil degranulation in atherosclerotic mice.

Eur J Clin Invest 2017 Feb 4;47(2):117-128. Epub 2017 Jan 4.

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa School of Medicine, Genoa, Italy.

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http://doi.wiley.com/10.1111/eci.12708
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February 2017

Advanced refractory heart failure: conservative or interventional approach?

Eur J Clin Invest 2017 02 29;47(2):193-194. Epub 2016 Dec 29.

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa and IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy.

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http://dx.doi.org/10.1111/eci.12712DOI Listing
February 2017

The pathophysiological role of cholecystokinin-1 receptor in mouse cholelithogenesis.

Eur J Clin Invest 2017 02 29;47(2):195-196. Epub 2016 Dec 29.

Department of Internal Medicine, First Clinic of Internal Medicine, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1111/eci.12713DOI Listing
February 2017

GPR55 agonist lysophosphatidylinositol and lysophosphatidylcholine inhibit endothelial cell hyperpolarization via GPR-independent suppression of Na-Ca exchanger and endoplasmic reticulum Ca refilling.

Vascul Pharmacol 2017 02 5;89:39-48. Epub 2017 Jan 5.

Division of Cardiology, Foundation for Medical Researches, Department of Internal Medicine, University of Geneva, Av. de la Roseraie 64, CH-1211 Geneva 4, Switzerland.

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http://dx.doi.org/10.1016/j.vph.2017.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520228PMC
February 2017

The Role of Adipocytokines in Coronary Atherosclerosis.

Curr Atheroscler Rep 2017 02;19(2):10

Department of Internal Medicine, University of Genoa, 6 Viale Benedetto XV, 16132, Genoa, Italy.

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http://dx.doi.org/10.1007/s11883-017-0644-3DOI Listing
February 2017

Pathophysiological relevance of macrophage subsets in atherogenesis.

Thromb Haemost 2017 01 29;117(1):7-18. Epub 2016 Sep 29.

Fabrizio Montecucco, MD, PhD, Department of Internal Medicine, University of Genoa School of Medicine, 6 viale Benedetto XV, 16132 Genoa, Italy, Tel.: +39 010 353 8694, Fax: +39 010 353 8686, E-mail:

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http://dx.doi.org/10.1160/TH16-08-0593DOI Listing
January 2017

Decreased serum PCSK9 levels after ischaemic stroke predict worse outcomes.

Eur J Clin Invest 2016 Dec 10;46(12):1053-1062. Epub 2016 Nov 10.

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1111/eci.12692DOI Listing
December 2016

Update on the effects of treatment with recombinant tissue-type plasminogen activator (rt-PA) in acute ischemic stroke.

Expert Opin Biol Ther 2016 Nov 7;16(11):1323-1340. Epub 2016 Sep 7.

a First Clinic of Internal Medicine, Department of Internal Medicine , University of Genoa School of Medicine , Genoa , Italy.

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http://dx.doi.org/10.1080/14712598.2016.1227779DOI Listing
November 2016

Update on Inflammatory Biomarkers and Treatments in Ischemic Stroke.

Int J Mol Sci 2016 Nov 25;17(12). Epub 2016 Nov 25.

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy.

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http://dx.doi.org/10.3390/ijms17121967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187767PMC
November 2016

The peak of blood lactate during the first 24h predicts mortality in acute coronary syndrome patients under extracorporeal membrane oxygenation.

Int J Cardiol 2016 Oct 6;221:741-5. Epub 2016 Jul 6.

Intensive Care Unit, Departement of Anesthesiology and Intensive Care Specialities, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, 1205 Geneva, Switzerland.

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http://dx.doi.org/10.1016/j.ijcard.2016.07.065DOI Listing
October 2016

Vitamin D receptor is expressed within human carotid plaques and correlates with pro-inflammatory M1 macrophages.

Vascul Pharmacol 2016 10 20;85:57-65. Epub 2016 Aug 20.

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy; IRCCS AOU San Martino - IST, Largo Benzi 10, 16100 Genoa, Italy.

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http://dx.doi.org/10.1016/j.vph.2016.08.004DOI Listing
October 2016

Treatment with the GPR55 antagonist CID16020046 increases neutrophil activation in mouse atherogenesis.

Thromb Haemost 2016 Oct 28;116(5):987-997. Epub 2016 Jul 28.

Prof. Fabrizio Montecucco, MD, PhD, First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy, Tel.: +39 010 353 86 94, Fax: +39 010 353 86 86, E-mail:

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http://dx.doi.org/10.1160/TH16-02-0139DOI Listing
October 2016

Association between anti-apolipoprotein A-1 antibodies and cardiovascular disease in the general population. Results from the CoLaus study.

Thromb Haemost 2016 Sep 7;116(4):764-71. Epub 2016 Jul 7.

Dr. Panagiotis Antiochos, CoLaus Study, Bâtiment des Instituts, 19, Rue du Bugnon, CH-1005 Lausanne, Switzerland, Tel.: +41 79 556 03 11, Fax: +41 21 314 80 37, E-mail:

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http://dx.doi.org/10.1160/TH16-03-0248DOI Listing
September 2016

Anti-ApoA-1 IgG serum levels predict worse poststroke outcomes.

Eur J Clin Invest 2016 Sep;46(9):805-17

Division of Laboratory Medicine, Department of Genetics and Laboratory Medicine, Geneva University Hospitals, Geneva, Switzerland.

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http://dx.doi.org/10.1111/eci.12664DOI Listing
September 2016

Therapeutic hypothermia in ST elevation myocardial infarction (STEMI): a long way to go.

J Thorac Dis 2016 Aug;8(8):E796-8

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genova, Italy;; IRCCS AOU San Martino - IST, largo Benzi 10, 16143 Genova, Italy.

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http://dx.doi.org/10.21037/jtd.2016.06.53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999739PMC
August 2016

Sofosbuvir/velpatasvir: A promising combination.

World J Hepatol 2016 Jul;8(19):785-9

Aldo Bonaventura, Fabrizio Montecucco, First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa School of Medicine, IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, 16132 Genoa, Italy.

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http://dx.doi.org/10.4254/wjh.v8.i19.785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937166PMC
July 2016