Publications by authors named "Fabrizio Carta"

179Publications

Handling drug-target selectivity: A study on ureido containing Carbonic Anhydrase inhibitors.

Eur J Med Chem 2020 Nov 21:113035. Epub 2020 Nov 21.

Università Degli Studi di Firenze, NEUROFARBA Dept, Sezione di Scienze Farmaceutiche e Nutraceutiche, Via Ugo Schiff 6, 50019, Sesto Fiorentino, Florence, Italy.

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November 2020

Response to Perspectives on the Classical Enzyme Carbonic Anhydrase and the Search for Inhibitors.

Biophys J 2021 Jan 8;120(1):178-181. Epub 2020 Dec 8.

Neurofarba Department, Pharmaceutical and Nutraceutical Section, University of Florence, Sesto Fiorentino, Florence, Italy. Electronic address:

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January 2021

Chagas Disease: Perspectives on the Past and Present and Challenges in Drug Discovery.

Molecules 2020 Nov 23;25(22). Epub 2020 Nov 23.

BIOINOVAR-Biocatalysis, Bioproducts and Bioenergy, Institute of Microbiology Paulo de Góes, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, Brazil.

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November 2020

Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment.

Metabolites 2020 Oct 14;10(10). Epub 2020 Oct 14.

Neurofarba Department, Pharmaceutical and Nutraceutical Section, University of Florence, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.

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October 2020

Benzylaminoethylureido-Tailed Benzenesulfonamides Show Potent Inhibitory Activity against Bacterial Carbonic Anhydrases.

ChemMedChem 2020 Dec 28;15(24):2444-2447. Epub 2020 Oct 28.

NEUROFARBA Department, University of Florence, Via Ugo Schiff 6, 50019, Sesto Fiorentino, Italy.

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December 2020

Toxicity evaluation of sulfamides and coumarins that efficiently inhibit human carbonic anhydrases.

J Enzyme Inhib Med Chem 2020 Dec;35(1):1765-1772

Neurofarba Department, Sezione di Chimica Farmaceutica e Nutraceutica, Università degli Studi di Firenze, Firenze, Italy.

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December 2020

Effects of New NSAID-CAI Hybrid Compounds in Inflammation and Lung Fibrosis.

Biomolecules 2020 09 10;10(9). Epub 2020 Sep 10.

Department of NEUROFARBA, Pharmaceutical Science Section, University of Florence, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.

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September 2020

Unconventional amino acids in medicinal chemistry: First report on taurine merged within carbonic anhydrase inhibitors.

Bioorg Chem 2020 10 26;103:104236. Epub 2020 Aug 26.

Università degli Studi di Firenze, Laboratorio di Chimica Bioinorganica, Rm. 188, Via Della Lastruccia 3, I-50019 Sesto Fiorentino (Firenze), Italy.

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October 2020

Azidothymidine "Clicked" into 1,2,3-Triazoles: First Report on Carbonic Anhydrase-Telomerase Dual-Hybrid Inhibitors.

J Med Chem 2020 07 10;63(13):7392-7409. Epub 2020 Jun 10.

NEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, Università degli Studi di Firenze, Via Ugo Schiff 6, 50019 Sesto Fiorentino (Florence), Italy.

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July 2020

Glycomimetic Based Approach toward Selective Carbonic Anhydrase Inhibitors.

ACS Med Chem Lett 2020 May 11;11(5):727-731. Epub 2020 Mar 11.

Dipartimento di Chimica "Ugo Schiff", Università di Firenze, via della Lastruccia n. 3-13, Sesto Fiorentino, 50019 Firenze, Italy.

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May 2020

N-aryl-N'-ureido-O-sulfamates as potent and selective inhibitors of hCA VB over hCA VA: Deciphering the binding mode of new potential agents in mitochondrial dysfunctions.

Bioorg Chem 2020 07 4;100:103896. Epub 2020 May 4.

University of Florence, NEUROFARBA Dept., Sezione di Scienze Farmaceutiche e Nutraceutiche, Via Ugo Schiff 6, 50019 Sesto Fiorentino (Florence), Italy. Electronic address:

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July 2020

Crystal Structure of a Tetrameric Type II β-Carbonic Anhydrase from the Pathogenic Bacterium .

Molecules 2020 May 12;25(10). Epub 2020 May 12.

NEUROFARBA Department, Sezione di Scienze Farmaceutiche, Via Ugo Schiff 6, Università degli Studi di Firenze, 50019 Sesto Fiorentino (Florence), Italy.

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May 2020

A deadly spillover: SARS-CoV-2 outbreak.

Expert Opin Ther Pat 2020 Jul 29;30(7):481-485. Epub 2020 Apr 29.

Dipartimento Neurofarba, Sezione Di Scienze Farmaceutiche E Nutraceutiche, Università Degli Studi Di Firenze , Sesto Fiorentino (Florence), Italy.

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July 2020

Benzylaminoethyureido-Tailed Benzenesulfonamides: Design, Synthesis, Kinetic and X-ray Investigations on Human Carbonic Anhydrases.

Int J Mol Sci 2020 Apr 7;21(7). Epub 2020 Apr 7.

Dipartimento Neurofarba, Università degli Studi di Firenze, Sezione di Scienze Farmaceutiche, Polo Scientifico, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.

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April 2020

Tellurides Bearing Sulfonamides as Novel Inhibitors of Leishmanial Carbonic Anhydrase with Potent Antileishmanial Activity.

J Med Chem 2020 04 9;63(8):4306-4314. Epub 2020 Apr 9.

NEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, University of Florence, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.

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April 2020