Publications by authors named "Fabrizio Carta"

179Publications

Dual Carbonic Anhydrase IX/XII Inhibitors and Carbon Monoxide Releasing Molecules Modulate LPS-Mediated Inflammation in Mouse Macrophages.

Authors:
Emanuela Berrino Simone Carradori Andrea Angeli Fabrizio Carta Claudiu T Supuran Paolo Guglielmi Cecilia Coletti Roberto Paciotti Helmut Schweikl Francesca Maestrelli Elisabetta Cerbai Marialucia Gallorini

Antioxidants (Basel) 2021 Jan 5;10(1). Epub 2021 Jan 5.

Department of Pharmacy, "G. d'Annunzio" University of Chieti-Pescara, via dei Vestini 31, 66100 Chieti, Italy.

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January 2021

Handling drug-target selectivity: A study on ureido containing Carbonic Anhydrase inhibitors.

Authors:
Ozlem Akgul Srishti Singh Jacob T Andring Robert McKenna Silvia Selleri Fabrizio Carta Andrea Angeli Claudiu T Supuran

Eur J Med Chem 2020 Nov 21:113035. Epub 2020 Nov 21.

Università Degli Studi di Firenze, NEUROFARBA Dept, Sezione di Scienze Farmaceutiche e Nutraceutiche, Via Ugo Schiff 6, 50019, Sesto Fiorentino, Florence, Italy.

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November 2020

Response to Perspectives on the Classical Enzyme Carbonic Anhydrase and the Search for Inhibitors.

Authors:
Andrea Angeli Fabrizio Carta Alessio Nocentini Jean-Yves Winum Raivis Zalubovskis Valentina Onnis Wagdy M Eldehna Clemente Capasso Simone Carradori William A Donald Shoukat Dedhar Claudiu T Supuran

Biophys J 2021 Jan 8;120(1):178-181. Epub 2020 Dec 8.

Neurofarba Department, Pharmaceutical and Nutraceutical Section, University of Florence, Sesto Fiorentino, Florence, Italy. Electronic address:

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January 2021

Chagas Disease: Perspectives on the Past and Present and Challenges in Drug Discovery.

Authors:
Felipe Raposo Passos Mansoldo Fabrizio Carta Andrea Angeli Veronica da Silva Cardoso Claudiu T Supuran Alane Beatriz Vermelho

Molecules 2020 Nov 23;25(22). Epub 2020 Nov 23.

BIOINOVAR-Biocatalysis, Bioproducts and Bioenergy, Institute of Microbiology Paulo de Góes, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, Brazil.

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November 2020

Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment.

Authors:
Andrea Angeli Fabrizio Carta Alessio Nocentini Jean-Yves Winum Raivis Zalubovskis Atilla Akdemir Valentina Onnis Wagdy M Eldehna Clemente Capasso Giuseppina De Simone Simona Maria Monti Simone Carradori William A Donald Shoukat Dedhar Claudiu T Supuran

Metabolites 2020 Oct 14;10(10). Epub 2020 Oct 14.

Neurofarba Department, Pharmaceutical and Nutraceutical Section, University of Florence, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.

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October 2020

Benzylaminoethylureido-Tailed Benzenesulfonamides Show Potent Inhibitory Activity against Bacterial Carbonic Anhydrases.

Authors:
Majid Ali Andrea Angeli Murat Bozdag Fabrizio Carta Clemente Capasso Umar Farooq Claudiu T Supuran

ChemMedChem 2020 Dec 28;15(24):2444-2447. Epub 2020 Oct 28.

NEUROFARBA Department, University of Florence, Via Ugo Schiff 6, 50019, Sesto Fiorentino, Italy.

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December 2020

Toxicity evaluation of sulfamides and coumarins that efficiently inhibit human carbonic anhydrases.

Authors:
Ashok Aspatwar Emanuela Berrino Silvia Bua Fabrizio Carta Clemente Capasso Seppo Parkkila Claudiu T Supuran

J Enzyme Inhib Med Chem 2020 Dec;35(1):1765-1772

Neurofarba Department, Sezione di Chimica Farmaceutica e Nutraceutica, Università degli Studi di Firenze, Firenze, Italy.

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December 2020

Effects of New NSAID-CAI Hybrid Compounds in Inflammation and Lung Fibrosis.

Authors:
Laura Lucarini Mariaconcetta Durante Silvia Sgambellone Cecilia Lanzi Elisabetta Bigagli Ozlem Akgul Emanuela Masini Claudiu T Supuran Fabrizio Carta

Biomolecules 2020 09 10;10(9). Epub 2020 Sep 10.

Department of NEUROFARBA, Pharmaceutical Science Section, University of Florence, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.

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September 2020

Unconventional amino acids in medicinal chemistry: First report on taurine merged within carbonic anhydrase inhibitors.

Authors:
Özlem Akgül Andrea Angeli Daniela Vullo Fabrizio Carta Claudiu T Supuran

Bioorg Chem 2020 10 26;103:104236. Epub 2020 Aug 26.

Università degli Studi di Firenze, Laboratorio di Chimica Bioinorganica, Rm. 188, Via Della Lastruccia 3, I-50019 Sesto Fiorentino (Firenze), Italy.

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October 2020

In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with IX and XII CA Inhibition.

Authors:
Giosuè Costa Annalisa Maruca Roberta Rocca Francesca Alessandra Ambrosio Emanuela Berrino Fabrizio Carta Francesco Mesiti Alessandro Salatino Delia Lanzillotta Francesco Trapasso Anna Artese Stefano Alcaro Claudiu T Supuran

Antioxidants (Basel) 2020 Aug 21;9(9). Epub 2020 Aug 21.

Dipartimento NEUROFARBA, Sezione di Scienze Farmaceutiche, Università degli Studi di Firenze, Sesto Fiorentino, 50019 Florence, Italy.

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August 2020

Synthesis, Computational Studies and Assessment of in Vitro Activity of Squalene Derivatives as Carbonic Anhydrase Inhibitors.

Authors:
Lilia Clima Bogdan Florin Craciun Andrea Angeli Andrea Petreni Alessandro Bonardi Alessio Nocentini Fabrizio Carta Paola Gratteri Mariana Pinteala Claudiu T Supuran

ChemMedChem 2020 Nov 15;15(21):2052-2057. Epub 2020 Sep 15.

Sezione di Scienze Farmaceutiche, University of Florence, Via Ugo Schiff 6, 50019, Sesto Fiorentino, Italy.

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November 2020

2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site.

Authors:
Murat Bozdag Claudiu T Supuran Davide Esposito Andrea Angeli Fabrizio Carta Simona Maria Monti Giuseppina De Simone Vincenzo Alterio

Chem Commun (Camb) 2020 Jul;56(59):8297-8300

Istituto di Biostrutture e Bioimmagini-CNR, Naples, Italy.

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July 2020

The role of carbonic anhydrases in extinction of contextual fear memory.

Authors:
Scheila Daiane Schmidt Alessia Costa Barbara Rani Eduarda Godfried Nachtigall Maria Beatrice Passani Fabrizio Carta Alessio Nocentini Jociane de Carvalho Myskiw Cristiane Regina Guerino Furini Claudiu T Supuran Ivan Izquierdo Patrizio Blandina Gustavo Provensi

Proc Natl Acad Sci U S A 2020 07 22;117(27):16000-16008. Epub 2020 Jun 22.

Department of Neuroscience, Psychology, Drug Research, and Child Health, University of Florence, 50121 Florence, Italy;

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July 2020

Azidothymidine "Clicked" into 1,2,3-Triazoles: First Report on Carbonic Anhydrase-Telomerase Dual-Hybrid Inhibitors.

Authors:
Emanuela Berrino Andrea Angeli Dmitry D Zhdanov Anna P Kiryukhina Andrea Milaneschi Alessandro De Luca Murat Bozdag Simone Carradori Silvia Selleri Gianluca Bartolucci Thomas S Peat Marta Ferraroni Claudiu T Supuran Fabrizio Carta

J Med Chem 2020 07 10;63(13):7392-7409. Epub 2020 Jun 10.

NEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, Università degli Studi di Firenze, Via Ugo Schiff 6, 50019 Sesto Fiorentino (Florence), Italy.

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July 2020

Glycomimetic Based Approach toward Selective Carbonic Anhydrase Inhibitors.

Authors:
Debora Pratesi Camilla Matassini Andrea Goti Andrea Angeli Fabrizio Carta Claudiu T Supuran Rolando Spanevello Francesca Cardona

ACS Med Chem Lett 2020 May 11;11(5):727-731. Epub 2020 Mar 11.

Dipartimento di Chimica "Ugo Schiff", Università di Firenze, via della Lastruccia n. 3-13, Sesto Fiorentino, 50019 Firenze, Italy.

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May 2020

N-aryl-N'-ureido-O-sulfamates as potent and selective inhibitors of hCA VB over hCA VA: Deciphering the binding mode of new potential agents in mitochondrial dysfunctions.

Authors:
Giulio Poli Murat Bozdag Emanuela Berrino Andrea Angeli Tiziano Tuccinardi Fabrizio Carta Claudiu T Supuran

Bioorg Chem 2020 07 4;100:103896. Epub 2020 May 4.

University of Florence, NEUROFARBA Dept., Sezione di Scienze Farmaceutiche e Nutraceutiche, Via Ugo Schiff 6, 50019 Sesto Fiorentino (Florence), Italy. Electronic address:

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July 2020

Crystal Structure of a Tetrameric Type II β-Carbonic Anhydrase from the Pathogenic Bacterium .

Authors:
Andrea Angeli Marta Ferraroni Mariana Pinteala Stelian S Maier Bogdan C Simionescu Fabrizio Carta Sonia Del Prete Clemente Capasso Claudiu T Supuran

Molecules 2020 May 12;25(10). Epub 2020 May 12.

NEUROFARBA Department, Sezione di Scienze Farmaceutiche, Via Ugo Schiff 6, Università degli Studi di Firenze, 50019 Sesto Fiorentino (Florence), Italy.

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May 2020

A deadly spillover: SARS-CoV-2 outbreak.

Authors:
Mattia Mori Clemente Capasso Fabrizio Carta William A Donald Claudiu T Supuran

Expert Opin Ther Pat 2020 Jul 29;30(7):481-485. Epub 2020 Apr 29.

Dipartimento Neurofarba, Sezione Di Scienze Farmaceutiche E Nutraceutiche, Università Degli Studi Di Firenze , Sesto Fiorentino (Florence), Italy.

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July 2020

Benzylaminoethyureido-Tailed Benzenesulfonamides: Design, Synthesis, Kinetic and X-ray Investigations on Human Carbonic Anhydrases.

Authors:
Majid Ali Murat Bozdag Umar Farooq Andrea Angeli Fabrizio Carta Paola Berto Giuseppe Zanotti Claudiu T Supuran

Int J Mol Sci 2020 Apr 7;21(7). Epub 2020 Apr 7.

Dipartimento Neurofarba, Università degli Studi di Firenze, Sezione di Scienze Farmaceutiche, Polo Scientifico, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.

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April 2020

Tellurides Bearing Sulfonamides as Novel Inhibitors of Leishmanial Carbonic Anhydrase with Potent Antileishmanial Activity.

Authors:
Andrea Angeli Mikel Etxebeste-Mitxeltorena Carmen Sanmartín Socorro Espuelas Esther Moreno Amaya Azqueta Seppo Parkkila Fabrizio Carta Claudiu T Supuran

J Med Chem 2020 04 9;63(8):4306-4314. Epub 2020 Apr 9.

NEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, University of Florence, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.

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April 2020