Fabrice Barlesi

Fabrice Barlesi

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Fabrice Barlesi

Publications by authors named "Fabrice Barlesi"

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Functional status in a geriatric oncology setting: A review.

J Geriatr Oncol 2019 Nov 27;10(6):884-894. Epub 2019 Feb 27.

Department of Geriatrics, Geriatric Oncology Unit, APHP, Hospital European Georges Pompidou, Paris, France; Clinical Epidemiology and Ageing Unit, EA, 7376, Universite' Paris-Est, Creteil, France.

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http://dx.doi.org/10.1016/j.jgo.2019.02.004DOI Listing
November 2019

Nivolumab plus Ipilimumab in Advanced Non-Small-Cell Lung Cancer.

N Engl J Med 2019 Sep 28. Epub 2019 Sep 28.

From the Memorial Sloan Kettering Cancer Center, New York (M.D.H.); Hospital Universitario Doce de Octubre, Centro Nacional de Investigaciones Oncológicas, Universidad Complutense, and Centro de Investigación Biomédica en Red de Cáncer, Madrid (L.P.-A.), Hospital Universitario Virgen Del Rocio, Seville (R.B.C.), and the Catalan Institute of Oncology-Germans Trias i Pujol Hospital, Badalona (E.C.C.) - all in Spain; Ambulatorium Chemioterapii, Bydgoszcz, Poland (B.Z.); the Asan Medical Center (S.-W.K.) and the Samsung Medical Center at Sungkyunkwan University School of Medicine (K.P.) - both in Seoul, South Korea; the Institute of Oncology Prof. Dr. Alexandru Trestioreanu, Bucharest, Romania (A.A.); the Hospital Italiano de Buenos Aires, Buenos Aires (L.L.); Instituto Jalisciense de Cancerologia, Guadalajara, Mexico (E.M.J.); the Saitama Cancer Center, Saitama, Japan (H.S.); Matrai Gyogyintezet, Matrahaza, Hungary (I.A.); Limoges University Hospital, Limoges (A.V.), and Aix-Marseille University, National Center for Scientific Research, INSERM, Centre de Recherche en Cancérologie de Marseille, Assistance Publique-Hôpitaux de Marseille, Marseille (F.B.) - all in France; Centre Hospitalier Universitaire Vaudois, Lausanne University, Lausanne, Switzerland (S.P.); Sotiria General Hospital, National and Kapodistrian University of Athens, Athens (K.S.); Lung Clinic Grosshansdorf, Airway Research Center North, German Center of Lung Research, Grosshansdorf, Germany (M.R.); Fox Chase Cancer Center, Philadelphia (H.B.); Johns Hopkins Kimmel Cancer Center, Baltimore (J.R.B.); Princess Alexandra Hospital, Brisbane, QLD, Australia (K.J.O.); Bristol-Myers Squibb, Princeton, NJ (W.J.G., P.B., S.K.R., R.S.K., F.E.N.); and Winship Cancer Institute, Emory University, Atlanta (S.S.R.).

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http://dx.doi.org/10.1056/NEJMoa1910231DOI Listing
September 2019

Alectinib in the treatment of ALK-positive metastatic non-small cell lung cancer: clinical trial evidence and experience with a focus on brain metastases.

Ther Adv Respir Dis 2019 Jan-Dec;13:1753466619831906

Service d'Oncologie Multidisciplinaire et Innovations Thérapeutiques, Hôpital Nord, Chemin des Bourrely, 13915 Marseille Cedex, FranceAix Marseille University, APHM, CNRS, INSERM, CRCM, Hôpital Nord, Oncologie Multidisciplinaire et Innovations Thérapeutiques, Marseille, France.

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http://dx.doi.org/10.1177/1753466619831906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385324PMC
August 2019

First-line immune checkpoint blockade for advanced non-small-cell lung cancer: Travelling at the speed of light.

Lung Cancer 2019 Aug 19;134:245-253. Epub 2019 Jun 19.

Department of Medical Oncology, The Christie NHS Foundation Trust, Manchester, United Kingdom; Department of Medical Oncology, Manchester University NHS Foundation Trust, Manchester, United Kingdom; Division of Cancer Sciences, University of Manchester, Manchester, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2019.06.007DOI Listing
August 2019

Critical Assessment in Routine Clinical Practice of Liquid Biopsy for EGFR Status Testing in Non-Small-Cell Lung Cancer: A Single-Laboratory Experience (LPCE, Nice, France).

Clin Lung Cancer 2019 Aug 3. Epub 2019 Aug 3.

Institute of Research on Cancer and Ageing of Nice (IRCAN), Inserm U1081, CNRS UMR7284, Team 4, Université Côte d'Azur, CHU de Nice, Nice, France; Laboratory of Clinical and Experimental Pathology (LPCE), Université Côte d'Azur, CHU de Nice, University Hospital Federation OncoAge, Nice, France; Hospital-Integrated Biobank (BB-0033-00025), Université Côte d'Azur, CHU de Nice, University Hospital Federation OncoAge, Hospital-Integrated Biobank (BB-0033-00025), Nice, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15257304193021
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http://dx.doi.org/10.1016/j.cllc.2019.07.010DOI Listing
August 2019

Efficacy of Immune Checkpoint Inhibitors in KRAS-Mutant Non-Small Cell Lung Cancer (NSCLC).

J Thorac Oncol 2019 Jun 6;14(6):1095-1101. Epub 2019 Feb 6.

Aix Marseille University, Assistance Publique Hôpitaux de Marseille, Department of Multidisciplinary Oncology and Therapeutic Innovations. Marseille, France; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm UMR1068, CNRS UMR7258, Marseille, France.

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http://dx.doi.org/10.1016/j.jtho.2019.01.011DOI Listing
June 2019

Association Between Immune-related Adverse Events and Efficacy of Immune Checkpoint Inhibitors in Non-small-cell Lung Cancer.

Clin Lung Cancer 2019 05 11;20(3):201-207. Epub 2018 Oct 11.

Multidisciplinary Oncology and Therapeutic Innovations Department, Aix Marseille University, Assistance Publique Hôpitaux de Marseille, Marseille, France; Aix Marseille University, Inserm U911 CRO2, Marseille, France.

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https://linkinghub.elsevier.com/retrieve/pii/S15257304183026
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http://dx.doi.org/10.1016/j.cllc.2018.10.002DOI Listing
May 2019

Companion diagnostic tests for treatment of lung cancer patients: what are the current and future challenges?

Expert Rev Mol Diagn 2019 May 6;19(5):429-438. Epub 2019 May 6.

b CRCM, INSERM, CNRS, AP-HM, Multidisciplinary Oncology and Therapeutic Innovations Department , Aix Marseille University , Marseille , France.

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http://dx.doi.org/10.1080/14737159.2019.1611426DOI Listing
May 2019

Efficacy and safety of nivolumab in patients with non-small cell lung cancer: a retrospective study in clinical practice.

J Chemother 2019 Apr 30;31(2):90-94. Epub 2018 Dec 30.

c Oncologie multidisciplinaire et innovations thérapeutiques , AP-HM , Marseille , France.

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http://dx.doi.org/10.1080/1120009X.2018.1551753DOI Listing
April 2019

[Tumor banks and complex data management: Current and future challenges].

Ann Pathol 2019 Apr 25;39(2):137-143. Epub 2019 Feb 25.

Inserm, Inra, nutrition métabolismes et cancer, CRB-Santé, université de Rennes, rue Henri-Le-Guilloux, 35033 Rennes, France.

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http://dx.doi.org/10.1016/j.annpat.2019.01.017DOI Listing
April 2019

Therapeutic potential of trametinib to inhibit the mutagenesis by inactivating the protein kinase pathway in non-small cell lung cancer.

Expert Rev Anticancer Ther 2019 Jan 4;19(1):11-17. Epub 2018 Dec 4.

a Assistance Publique Hôpitaux de Marseille, Multidisciplinary Oncology & Therapeutic Innovations dpt , Aix Marseille University , Marseille , France.

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http://dx.doi.org/10.1080/14737140.2019.1554440DOI Listing
January 2019

The clinical utility of tumor mutational burden in non-small cell lung cancer.

Transl Lung Cancer Res 2018 Dec;7(6):639-646

Aix Marseille University, Assistance Publique Hôpitaux de Marseille, Multidisciplinary Oncology & Therapeutic Innovations department, Marseille, France.

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http://tlcr.amegroups.com/article/view/24870/18841
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http://dx.doi.org/10.21037/tlcr.2018.10.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249623PMC
December 2018

"I think it's a bit early for now": impact of psychological factors on drafting advance directives among cancer patients.

J Psychosoc Oncol 2019 Jan-Feb;37(1):37-49. Epub 2018 Dec 26.

b Aix Marseille Univ, LPS , Aix-en-Provence , France.

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http://dx.doi.org/10.1080/07347332.2018.1541494DOI Listing
December 2018

Specialists to the Rescue of Oncologists for the Management of Toxicity Occurring Under Combination of Anticancer Therapies.

J Thorac Oncol 2018 11;13(11):e231-e232

Marseille Early Phases Cancer Center CLIP2, and Department of Nephrology and Kidney Transplantation, Assistance Publique Hôpitaux de Marseille, Aix Marseille University, Marseille, France.

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https://linkinghub.elsevier.com/retrieve/pii/S15560864183077
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http://dx.doi.org/10.1016/j.jtho.2018.07.003DOI Listing
November 2018

Pemetrexed Continuation Maintenance Phase 3 Trials in Nonsquamous, Non-Small-Cell Lung Cancer: Focus on 2-Year Overall Survival and Continuum of Care.

Clin Lung Cancer 2018 11 26;19(6):e823-e830. Epub 2018 May 26.

Oncology at Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN.

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http://dx.doi.org/10.1016/j.cllc.2018.05.013DOI Listing
November 2018

Phase Ib/II study of the pan-cyclin-dependent kinase inhibitor roniciclib in combination with chemotherapy in patients with extensive-disease small-cell lung cancer.

Lung Cancer 2018 09 27;123:14-21. Epub 2018 Apr 27.

Aix Marseille University, Jardin du Pharo, 58, bd Charles Livon, 13284 Marseille, France; Assistance Publique Hôpitaux de Marseille, 80, rue Brochier, 13005 Marseille, France; Centre d'Essais Précoces en Cancérologie de Marseille (CLIP(2)), Hôpital La Timone - Basement F, 1st Floor, 264, rue St Pierre, 13885 Marseille, France. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2018.04.022DOI Listing
September 2018

Immunologically effective dose: a practical model for immuno-radiotherapy.

Oncotarget 2018 Aug 7;9(61):31812-31819. Epub 2018 Aug 7.

Simulation & Modelling Adaptive Response for Therapeutics in Cancer (SMARTc), Center for Research on Cancer of Marseille, CRCM Inserm UMR1068, CNRS UMR7258, Aix Marseille Université U105, Institut Paoli Calmettes, Marseille, France.

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http://www.oncotarget.com/fulltext/25746
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http://dx.doi.org/10.18632/oncotarget.25746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112752PMC
August 2018

Another Drawback for Clinical Trials Entry Criteria.

J Thorac Oncol 2018 07;13(7):e116-e117

Aix Marseille University, Assistance Publique Hopitaux de Marseille, Marseille, France.

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http://dx.doi.org/10.1016/j.jtho.2018.02.007DOI Listing
July 2018

Lamins in Lung Cancer: Biomarkers and Key Factors for Disease Progression through miR-9 Regulation?

Cells 2018 Jul 16;7(7). Epub 2018 Jul 16.

Aix Marseille Université, APHM, INSERM, MMG, Hôpital la Timone, Service de Biologie Cellulaire, 13385 Marseille, France.

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http://dx.doi.org/10.3390/cells7070078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071028PMC
July 2018

Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC.

N Engl J Med 2018 Jun 4;378(24):2288-2301. Epub 2018 Jun 4.

From the Florida Hospital Cancer Institute, Orlando (M.A.S.); Rocky Mountain Cancer Centers, Denver (R.M.J.); US Oncology, Houston (R.M.J.); Azienda Unità Sanitaria Locale della Romagna, Ravenna, Italy (F.C.); Instituto Nacional del Torax, Santiago, Chile (F.O.); Moscow City Oncology Hospital, Moscow (D.S.); National Hospital Organization Shikoku Cancer Center, Matsuyama, Japan (N.N.); Complejo Hospitalario Universitario Insular Materno-Infantil de Gran Canaria, Universidad de Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain (D.R.-A.); Centre Hospitalier Universitaire de Grenoble Alpes, Grenoble (D.M.-S.), and Aix Marseille University, Assistance Publique-Hôpitaux de Marseille, Marseille (F.B.) - both in France; New England Cancer Specialists, Scarborough, ME (C.A.T.); Allegheny Health Network Cancer Institute, Pittsburgh (G.F.); Genentech, South San Francisco, CA (C.K., A.L., S.C., Y.D., Y.S., M.K., A.L.-C., A.S.); and Lung Clinic Grosshansdorf, Airway Research Center North, German Center of Lung Research, Grosshansdorf, Germany (M.R.).

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http://www.nejm.org/doi/10.1056/NEJMoa1716948
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http://dx.doi.org/10.1056/NEJMoa1716948DOI Listing
June 2018

Cost-effectiveness of biomarker testing for treatment choices in advanced non-small cell lung carcinoma: impact of diagnostic strategies and their turnaround times.

Eur Respir J 2018 06 21;51(6). Epub 2018 Jun 21.

Assistance Publique Hôpitaux de Paris, Hôpital Tenon, Service de Pneumologie, Sorbonne Universités, UPMC Univ Paris 06, GRC n04, Theranoscan, Paris, France.

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http://dx.doi.org/10.1183/13993003.00844-2018DOI Listing
June 2018

Durvalumab after chemoradiotherapy in stage III non-small cell lung cancer.

J Thorac Dis 2018 Apr;10(Suppl 9):S1032-S1036

Aix Marseille University, Assistance Publique Hôpitaux de Marseille, Multidisciplinary Oncology & Therapeutic Innovations dpt, Marseille, France.

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http://jtd.amegroups.com/article/view/20558/15912
Publisher Site
http://dx.doi.org/10.21037/jtd.2018.04.61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949420PMC
April 2018

Drug repurposing in malignant pleural mesothelioma: a breath of fresh air?

Eur Respir Rev 2018 Mar 14;27(147). Epub 2018 Mar 14.

Aix Marseille University, Assistance Publique Hôpitaux de Marseille, Multidisciplinary Oncology and Therapeutic Innovations Dept, Marseille, France

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http://dx.doi.org/10.1183/16000617.0098-2017DOI Listing
March 2018

Dyadic effects of coping strategies, time perspectives, and personality on the quality of life of cancer patients and their caregivers.

Psychooncology 2018 02 6;27(2):590-599. Epub 2017 Oct 6.

EA3279, Self-perceived Health Assessment Research Unit, Aix Marseille Université, Marseille, France.

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http://dx.doi.org/10.1002/pon.4553DOI Listing
February 2018

Clustering based on unsupervised binary trees to define subgroups of cancer patients according to symptom severity in cancer.

Qual Life Res 2018 02 8;27(2):555-565. Epub 2017 Dec 8.

EA3279 Self-perceived Health Assessment Research Unit and Department of Public Health, APHM, Aix-Marseille University, 27 bd Jean Moulin, 13385, Marseille, France.

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http://dx.doi.org/10.1007/s11136-017-1760-9DOI Listing
February 2018

Nivolumab Versus Docetaxel in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer: Two-Year Outcomes From Two Randomized, Open-Label, Phase III Trials (CheckMate 017 and CheckMate 057).

J Clin Oncol 2017 Dec 12;35(35):3924-3933. Epub 2017 Oct 12.

Leora Horn, Vanderbilt-Ingram Cancer Center; David R. Spigel, Sarah Cannon Research Institute/Tennessee Oncology, Nashville, TN; Everett E. Vokes, University of Chicago, Chicago, IL; Esther Holgado, Hospital De Madrid, Norte Sanchinarro, Madrid; Enriqueta Felip, Hospital Universitari Vall d'Hebron, Barcelona; Luis Paz-Ares, Hospital Universitario Virgen Del Rocio, Seville, Spain; Neal Ready, Duke University Medical Center, Durham, NC; Martin Steins, Thoraxklinik-Heidelberg gGmbH, Heidelberg; Martin Kohlhäeufl, Robert-Bosch-Krankenhaus, Stuttgart; Martin Reck, LungenClinic Grosshansdorf, Airway Research Center North, German Center for Lung Research, Grosshansdorf; Wilfried E.E. Eberhardt, University Hospital and Ruhrlandclinic, University of Duisburg-Essen, Essen, Germany; Elena Poddubskaya, N.N. Blokhin Russian Cancer Research Center, Moscow, Russia; Hossein Borghaei, Fox Chase Cancer Center, Philadelphia, PA; Adam Pluzanski, Centrum Onkologii-Instytut Im. Marii Sklodowskiej-Curie, Warsaw, Poland; Karen L. Reckamp, City of Hope, Duarte, CA; Marco A. Burgio and Lucio Crinò, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Scientifico Romagnolo Per lo Studio e la Cura dei Tumori, Meldola, Italy; David Waterhouse, Oncology Hematology Care (OHC)/US Oncology, Cincinnati, OH; Fabrice Barlesi, Aix-Marseille Université, Assistance Publique Hôpitaux de Marseille, Marseille; Jérôme Fayette, Léon Bérard, Lyon, France; Scott Antonia, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Oscar Arrieta, Instituto Nacional De Cancerologia, Mexico City, Mexico; Naiyer Rizvi and Matthew D. Hellmann, Memorial Sloan Kettering Cancer Center, New York, NY; William J. Geese, Ang Li, Anne Blackwood-Chirchir, and Diane Healey, Bristol-Myers Squibb, Princeton, NJ; and Julie Brahmer, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD.

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http://dx.doi.org/10.1200/JCO.2017.74.3062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075826PMC
December 2017

Personalised medicine for nonsmall cell lung cancer.

Eur Respir Rev 2017 Dec 15;26(146). Epub 2017 Nov 15.

Aix Marseille University, Assistance Publique Hôpitaux de Marseille, Multidisciplinary Oncology and Therapeutic Innovations Dept, Marseille, France.

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http://dx.doi.org/10.1183/16000617.0066-2017DOI Listing
December 2017

Atezolizumab: feasible second-line therapy for patients with non-small cell lung cancer? A review of efficacy, safety and place in therapy.

Ther Adv Med Oncol 2017 Dec 19;9(12):769-779. Epub 2017 Dec 19.

Service d'Oncologie Multidisciplinaire & Innovations Thérapeutiques, Pôle Cardio-Vasculaire et Thoracique, Aix Marseille University, Assistance Publique - Hôpitaux de Marseille Hôpital Nord - Chemin des Bourrely, 13915 Marseille Cedex 20, France.

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http://dx.doi.org/10.1177/1758834017741074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808842PMC
December 2017

Bevacizumab Plus Radiosurgery for Nonsquamous Non-Small Cell Lung Cancer Patients with Brain Metastases: Safe Combination?

World Neurosurg 2017 Nov 9;107:1047.e1-1047.e4. Epub 2017 Aug 9.

Department of Multidisciplinary Oncology and Therapeutic Innovations, Aix Marseille University, Public Hospital, Marseille, France.

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http://dx.doi.org/10.1016/j.wneu.2017.07.185DOI Listing
November 2017

MEDI 4736 (durvalumab) in non-small cell lung cancer.

Expert Opin Biol Ther 2017 10 13;17(10):1317-1323. Epub 2017 Jul 13.

a Aix Marseille University, Assistance Publique Hôpitaux de Marseille , Early Phase Cancer Center CLIP2 , Marseille , France.

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http://dx.doi.org/10.1080/14712598.2017.1351939DOI Listing
October 2017

Phase III Trial of Ipilimumab Combined With Paclitaxel and Carboplatin in Advanced Squamous Non-Small-Cell Lung Cancer.

J Clin Oncol 2017 Oct 30;35(30):3449-3457. Epub 2017 Aug 30.

Ramaswamy Govindan, Washington University School of Medicine, St Louis, MO; Aleksandra Szczesna, Mazowieckie Centrum Leczenia Chorób Płuc i Gruźlicy, Otwock; Jacek Jassem, Medical University of Gdansk, Gdansk, Poland; Myung-Ju Ahn, Samsung Medical Center, Sungkyunkwan University, Seoul; Ki Hyeong Lee, Chungbuk National University Hospital, Cheongju-si, Republic of Korea; Claus-Peter Schneider, Zentralklinik Bad Berka, Bad Berka; Joachim Von Pawel, Asklepius Fachkliniken, Gauting; Martin Reck, LungenClinic Grosshansdorf, Airway Research Center North, German Center for Lung Research, Grosshansdorf, Germany; Pablo Fernando Gonzalez Mella, Centro de Investigaciones Clinicas, Universidad de Valparaíso and Fundación Arturo López Pérez, Santiago, Chile; Fabrice Barlesi, Aix Marseille University, Assistance Publique-Hôpitaux de Marseille, Marseille, France; Baohui Han, Shanghai Chest Hospital Affiliated to Shanghai JiaoTong University, Shanghai; Li Zhang, Sun Yat-Sen University Cancer Center, Guangzhou, People's Republic of China; Doina Elena Ganea, Spitalul Judetean De Urgenta Suceava, Sfântul loan cel Nou, Suceava, Romania; Vladimir Vladimirov, State Healthcare Institute, Pyatigorsk Oncology Dispensary, Pyatigorsk; Natalia Fadeeva, Chelyabinsk Regional Oncology Dispensary, Chelyabinsk, Russian Federation; Takayasu Kurata, Kansai Medical University Hirakata Hospital, Osaka; Tomohide Tamura, St Luke's International Hospital, Tokyo, Japan; Pieter E. Postmus, University of Liverpool, Liverpool, United Kingdom; Kenneth O'Byrne, Princess Alexandra Hospital and Queensland University of Technology, Brisbane, Queensland, Australia; and Justin Kopit, Mingshun Li, and Marina Tschaika, Bristol-Myers Squibb, Princeton, NJ.

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http://ascopubs.org/doi/10.1200/JCO.2016.71.7629
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http://dx.doi.org/10.1200/JCO.2016.71.7629DOI Listing
October 2017

Practices in management of cancer treatment-related cardiovascular toxicity: A cardio-oncology survey.

Int J Cardiol 2017 Aug 21;241:387-392. Epub 2017 Mar 21.

Aix-Marseille University, Assistance Publique - Hôpitaux de Marseille (AP-HM), Mediterranean University Cardio-Oncology Center (MEDI-CO Center), Unit of Heart Failure and Valvular Heart Diseases, Department of Cardiology, Hôpital Nord, France; Mediterranean Association for Research and Studies in Cardiology (MARS Cardio), France; Groupe Méditerranéen de Cardio-Oncologie (gMEDICO), France; Aix-Marseille University, Assistance Publique - Hôpitaux de Marseille (AP-HM), Oncosaftey Network of the Early Phases Cancer Trials Center (CLIP(2)), France. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.02.154DOI Listing
August 2017

Subclonal Therapy by Two EGFR TKIs Guided by Sequential Plasma Cell-free DNA in EGFR-Mutated Lung Cancer.

J Thorac Oncol 2017 07 7;12(7):e81-e84. Epub 2017 Mar 7.

Department of Cell and Developmental Biology, Sackler School of Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv, Israel.

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http://dx.doi.org/10.1016/j.jtho.2017.02.023DOI Listing
July 2017

[The management of bone metastasis].

Bull Cancer 2017 Jun 6;104(6):585-592. Epub 2017 Apr 6.

Aix-Marseille université, Assistance publique-Hôpitaux de Marseille, service d'oncologie multidisciplinaire et innovations thérapeutiques, 13920 Marseille cedex 15, France; Aix-Marseille université, faculté de médecine, centre de recherche en oncologie biologique et oncopharmacologie, Inserm U911, 13005 Marseille, France.

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http://dx.doi.org/10.1016/j.bulcan.2017.02.004DOI Listing
June 2017

Domains of quality of life freely expressed by cancer patients and their caregivers: contribution of the SEIQoL.

Health Qual Life Outcomes 2017 May 12;15(1):99. Epub 2017 May 12.

EA3279, Self-perceived Health Assessment Research Unit, Aix Marseille Université, 27 bd Jean Moulin, Marseille, cedex 05, F-13385, France.

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http://dx.doi.org/10.1186/s12955-017-0672-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427569PMC
May 2017

Management and research in cancer treatment-related cardiovascular toxicity: Challenges and perspectives.

Int J Cardiol 2016 Dec 17;224:366-375. Epub 2016 Sep 17.

Aix-Marseille University, Assistance Publique - Hôpitaux de Marseille (AP-HM), Mediterranean university Cardio-Oncology center (MEDI-CO center), Unit of Heart Failure and Valvular Heart Diseases, Department of Cardiology, Hôpital Nord, France; Aix-Marseille University, Assistance Publique - Hôpitaux de Marseille (AP-HM), Oncosafety Network of the Early Phases Cancer Trials Center (CLIP(2)), France; Groupe Méditerranéen de Cardio-Oncologie (gMEDICO), France; Mediterranean Academic association for Research and Studies in Cardiology (MARS Cardio), France. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.09.046DOI Listing
December 2016

EGFR and KRAS Mutations Predict the Incidence and Outcome of Brain Metastases in Non-Small Cell Lung Cancer.

Int J Mol Sci 2016 Dec 18;17(12). Epub 2016 Dec 18.

Assistance Publique Hôpitaux de Marseille, Multidisciplinary Oncology & Therapeutic Innovations department. Aix Marseille University, Marseille 13015, France.

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http://dx.doi.org/10.3390/ijms17122132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187932PMC
December 2016

Bevacizumab in the treatment of nonsquamous non-small cell lung cancer: clinical trial evidence and experience.

Ther Adv Respir Dis 2016 10 23;10(5):485-91. Epub 2016 Jun 23.

Aix Marseille University - Assistance Publique Hôpitaux de Marseille, Multidisciplinary Oncology and Therapeutic Innovations Department, INSERM U911 CRO2, Marseille, France.

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http://dx.doi.org/10.1177/1753465816652083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933613PMC
October 2016

Mathematical Modeling of Cancer Immunotherapy and Its Synergy with Radiotherapy.

Cancer Res 2016 09 14;76(17):4931-40. Epub 2016 Jun 14.

Aix Marseille University, SMARTc Unit, Inserm S 911 CRO2, Marseille, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-3567DOI Listing
September 2016

Routine molecular profiling of patients with NSCLC - Authors' reply.

Lancet 2016 09;388(10049):1054-1055

Assistance Publique Hôpitaux de Marseille, Aix Marseille University, Marseille Cedex 20, France. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(16)31136-9DOI Listing
September 2016

Elderly selection on geriatric index assessment.

Ann Transl Med 2016 Jun;4(12):245

Multidisciplinary Oncology & Therapeutic Innovations Department, Assistance Publique Hôpitaux de Marseille, Aix Marseille University, Marseille, France;; Aix Marseille University, Inserm U911 CRO2, Marseille, France.

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http://dx.doi.org/10.21037/atm.2016.05.61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930517PMC
June 2016

Pemetrexed for advanced stage nonsquamous non-small cell lung cancer: latest evidence about its extended use and outcomes.

Ther Adv Med Oncol 2016 May 9;8(3):198-208. Epub 2016 May 9.

Aix Marseille University, Assistance Publique Hôpitaux de Marseille, Department of Multidisciplinary Oncology & Therapeutic Innovations, Marseille, France.

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http://dx.doi.org/10.1177/1758834016644155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872256PMC
May 2016

Computational oncology--mathematical modelling of drug regimens for precision medicine.

Nat Rev Clin Oncol 2016 Apr 24;13(4):242-54. Epub 2015 Nov 24.

Aix Marseille Université, INSERM, CRO2 UMR_S 911, Marseille 13005, France.

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http://dx.doi.org/10.1038/nrclinonc.2015.204DOI Listing
April 2016

Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC.

Oncoimmunology 2016 Apr 12;5(4):e1071008. Epub 2015 Aug 12.

Gustave Roussy Cancer Campus, Villejuif, France; Laboratoire d'Immunomonitoring en Oncologie, UMS 3655 CNRS / US 23 INSERM Gustave Roussy Cancer Campus, Villejuif, France; Centre d'Investigation Clinique en Biothérapies (CICBT) 1428, Villejuif, France; Laboratoire de Thérapie Cellulaire, Gustave Roussy Cancer Campus, Villejuif, France.

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http://dx.doi.org/10.1080/2162402X.2015.1071008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839329PMC
April 2016

Functional Analysis of the Adrenomedullin Pathway in Malignant Pleural Mesothelioma.

J Thorac Oncol 2016 Jan;11(1):94-107

Aix-Marseille University, CRO2 UMR 911, Marseille, France; INSERM, CRO2 UMR 911, Marseille, France; Assistance Publique Hopitaux de Marseille, Service de Transfert d'Oncologie Biologique, Marseille, France.

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http://dx.doi.org/10.1016/j.jtho.2015.09.004DOI Listing
January 2016

Metronomic reloaded: Theoretical models bringing chemotherapy into the era of precision medicine.

Semin Cancer Biol 2015 Dec 7;35:53-61. Epub 2015 Sep 7.

Metronomics Global Health Initiative, Marseille, France; INSERM UMR S_911 CRO2, Aix Marseille Univ., Marseille, France; Clinical Pharmacokinetics, La Timone University Hospital of Marseille, Marseille, France. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2015.09.002DOI Listing
December 2015

Hepatitis B virus reactivation in HBsAg-negative patients is associated with emergence of viral strains with mutated HBsAg and reverse transcriptase.

Virology 2015 Oct 14;484:354-63. Epub 2015 Jul 14.

Service d'Hépato-Gastroentérologie Centre Hospitalo-Universitaire Timone, Assistance Publique-Hôpitaux de Marseille, Marseille, France; Aix-Marseille Université UMR INSERM 911. Facultés de Médecine et de Pharmacie, Marseille, France. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2015.06.017DOI Listing
October 2015

Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung Cancer.

N Engl J Med 2015 Oct 27;373(17):1627-39. Epub 2015 Sep 27.

From the Fox Chase Cancer Center, Philadelphia (H.B.); Hospital Universitario Virgen del Rocio, Seville (L.P.-A.), Vall d'Hebron University Hospital and Vall d'Hebron Institute of Oncology, Barcelona (E.F.), and Hospital de Madrid, Norte Sanchinarro, Madrid (E.H.) - all in Spain; Vanderbilt-Ingram Cancer Center (L.H.), and Sarah Cannon Research Institute and Tennessee Oncology (D.R.S.) - both in Nashville; Thoraxklinik, Heidelberg University Hospital, Heidelberg (M.S.) and Robert-Bosch-Krankenhaus Stuttgart, Gerlingen (M.K.) - both in Germany; Duke University Medical Center, Durham, NC (N.E.R.); University of Washington, Seattle (L.Q.C.); University of Chicago Medicine and Biological Sciences, Chicago (E.E.V.); Aix Marseille University, Assistance Publique-Hôpitaux de Marseille, Marseille (F.B.), Centre Léon Bérard, Lyon (J.F.), and Centre Hospitalier Universitaire de Rennes, Rennes (H.L.) - all in France; Instituto Nacional de Cancerologia, Mexico City (O.A.); Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori IRCCS, Meldola, Forlì-Cesena (M.A.B.), and Ospedale di Perugia, Perugia (L.C.) - both in Italy; N.N. Blokhin Russian Cancer Research Center, Moscow (E.P.); University of Texas Southwestern Medical Center, Dallas (D.E.G.); Yale Comprehensive Cancer Center, New Haven, CT (S.N.G.); Memorial Sloan Kettering Cancer Center, New York (C.M.R., N.R.); University of Texas M.D. Anderson Cancer Center, Houston (G.R.B.); H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL (S.J.A.); Bristol-Myers Squibb, Princeton, NJ (C.D., C.T.H., F.G.F.); and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore (J.R.B.).

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http://dx.doi.org/10.1056/NEJMoa1507643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705936PMC
October 2015

Phase III Multinational, Randomized, Double-Blind, Placebo-Controlled Study of Tivantinib (ARQ 197) Plus Erlotinib Versus Erlotinib Alone in Previously Treated Patients With Locally Advanced or Metastatic Nonsquamous Non-Small-Cell Lung Cancer.

J Clin Oncol 2015 Aug 13;33(24):2667-74. Epub 2015 Jul 13.

Giorgio Scagliotti and Silvia Novello, University of Turin, Orbassano, Torino; Adolfo Favaretto, Istituto Oncologico Veneto, Padova; Armando Santoro, Istituto Clinico Humanitas, Milan, Italy; Joachim von Pawel, Asklepios-Fachkliniken München-Gauting, Munich, Germany; Rodryg Ramlau, Poznań University of Medical Sciences, Poznań, Poland; Fabrice Barlesi, Aix Marseille University, Assistance Publique Hôpitaux de Marseille, Marseille, France; Wallace Akerley, Huntsman Cancer Institute, Salt Lake City, UT; Sergey Orlov, St Petersburg State Medical University, St Petersburg, Russian Federation; David Spigel, Clinical Locations, Nashville, TN; Vera Hirsh, McGill University Health Centre, Montreal, Quebec; Frances A. Shepherd, Princess Margaret Cancer Centre, Toronto, Ontario, Canada; Lecia V. Sequist, Massachusetts General Hospital, Boston; Jeffrey S. Ross, Foundation Medicine, Cambridge; Brian Schwartz, ArQule, Woburn, MA; Alan Sandler, Genentech, San Francisco, CA; and Qiang Wang, Reinhard von Roemeling, and Dale Shuster, Daiichi Sankyo, Edison, NJ.

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http://dx.doi.org/10.1200/JCO.2014.60.7317DOI Listing
August 2015

Improving efficacy of the combination between antiangiogenic and chemotherapy: Time for mathematical modeling support.

Proc Natl Acad Sci U S A 2015 Jul 16;112(27):E3453. Epub 2015 Jun 16.

SMARTc Unit, Pharmacokinetics Laboratory, Inserm S_911 CRO2 Aix Marseille University, and La Timone University Hospital of Marseille, 13000 Marseille, France; Multidisciplinary Oncology and Therapeutic Innovations Unit, Nord University Hospital of Marseille, 13000 Marseille, France

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http://dx.doi.org/10.1073/pnas.1506689112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500227PMC
July 2015