Publications by authors named "Fabrice Barlesi"

100Publications

Atezolizumab vs Docetaxel in Pretreated Patients with Non-Small Cell Lung Cancer: Final Results From the Randomized Phase II POPLAR and Phase III OAK Clinical Trials.

J Thorac Oncol 2020 Nov 6. Epub 2020 Nov 6.

Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; Address: Samsung Medical Center, 81 Irwon-ro, Gananam-gu, Seoul, 06351, Korea.

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http://dx.doi.org/10.1016/j.jtho.2020.09.022DOI Listing
November 2020

Octogenarians treated for thoracic and lung cancers: Impact of comprehensive geriatric assessment.

J Geriatr Oncol 2020 Oct 20. Epub 2020 Oct 20.

Multidisciplinary Oncology and Therapeutic Innovations Department, AP-HM, Marseille, France; Aix-Marseille Univ, CNRS, INSERM, CRCM, Marseille, France.

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http://dx.doi.org/10.1016/j.jgo.2020.10.005DOI Listing
October 2020

[Predictable toxicities with futures immunotherapies or combinations].

Bull Cancer 2020 Oct 22;107(10):1069-1078. Epub 2020 Sep 22.

AP-HM, CNRS, Inserm, CRCM, Aix-Marseille université, hôpital Nord, service d'oncologie multidisciplinaire et innovations thérapeutiques, chemin des Bourrely, 13915 Marseille cedex, France. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2020.07.004DOI Listing
October 2020

KRAS Inhibition with Sotorasib in Advanced Solid Tumors.

N Engl J Med 2020 09 20;383(13):1207-1217. Epub 2020 Sep 20.

From the Department of Investigational Cancer Therapeutics, Phase I Clinical Trials Program, University of Texas M.D. Anderson Cancer Center, Houston (D.S.H., F.M.-B.); the Department of Medical Oncology and Experimental Therapeutics, City of Hope Comprehensive Cancer Center, Duarte (M.G.F.), the University of California, San Francisco, San Francisco (P.N.M.), and Amgen, Thousand Oaks (H.H., J.N., G.N., J.K., B.E.H., J.C., J.R.L., G.F.) - all in California; Duke University Medical Center, Durham, NC (J.H.S.); Royal Melbourne Hospital/Peter MacCallum Cancer Centre, Melbourne, VIC (J.D.), Queen Elizabeth Hospital and University of Adelaide, Woodville South, SA (T.J.P.), and Scientia Clinical Research, Randwick, NSW (J.C. Kuo) - all in Australia; the Department of Medicine, Division of Hematology/Oncology, Indiana University School of Medicine, Indianapolis (G.A.D.); Dana-Farber Cancer Institute, Harvard Medical School, Boston (G.I.S.); the Sarah Cannon Research Institute at HealthONE, Denver (G.S.F.); Princess Margaret Cancer Centre, University Health Network, Toronto (A.S.); Fox Chase Cancer Center, Philadelphia (C.S.D.); the University of Pittsburgh Medical Center Hillman Cancer Center, University of Pittsburgh, Pittsburgh (T.F.B.); Seoul National University College of Medicine (Y.-J.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine (K.P.), and the Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine (T.W.K.) - all in Seoul, South Korea; Roswell Park Cancer Institute, Buffalo (G.K.D.), and Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine, New York (P.L., B.T.L.) - all in New York; the University of Michigan, Ann Arbor (J.C. Krauss); the Department of Experimental Therapeutics, National Cancer Center Hospital East, Kashiwa, Japan (Y.K.); the Department of Medicine, Division of Oncology, University of Washington, Seattle (A.L.C.); Aix Marseille University, Centre National de la Recherche Scientifique, INSERM, Centre de Recherche en Cancérologie de Marseille, Assistance Publique-Hôpitaux de Marseille, Marseille, France (F.B.); Winship Cancer Institute of Emory University, Atlanta (S.S.R.); and the Alvin J. Siteman Cancer Center at Washington University School of Medicine, St. Louis (R.G.).

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http://dx.doi.org/10.1056/NEJMoa1917239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571518PMC
September 2020

Cardiovascular Toxicity Related to Cancer Treatment: A Pragmatic Approach to the American and European Cardio-Oncology Guidelines.

J Am Heart Assoc 2020 Sep 5;9(18):e018403. Epub 2020 Sep 5.

Unit of Heart Failure and Valvular Heart Diseases Department of Cardiology Nord Hospital Center for CardioVascular and Nutrition Research (C2VN) University Mediterranean Center of Cardio-Oncology (MEDI-CO Center) Assistance Publique - Hôpitaux de MarseilleAix-Marseille University Marseille France.

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http://dx.doi.org/10.1161/JAHA.120.018403DOI Listing
September 2020

Predictive molecular pathology in non-small cell lung cancer in France: The past, the present and the perspectives.

Cancer Cytopathol 2020 Sep;128(9):601-610

UMR-1138, INSERM, Département de Biologie, Hôpital Européen Georges-Pompidou, Paris, France.

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http://dx.doi.org/10.1002/cncy.22318DOI Listing
September 2020

Efficacy of Selpercatinib in -Altered Thyroid Cancers.

N Engl J Med 2020 08;383(9):825-835

From Massachusetts General Hospital (L.J.W.) and Dana-Farber Cancer Institute (J. Lorch), Boston; Memorial Sloan Kettering Cancer Center, New York (E.S., A.D.); Royal North Shore Hospital, St. Leonards, NSW (B.R.), and Peter MacCallum Cancer Institute, Melbourne, VIC (B.S.) - both in Australia; University of California, San Francisco-Helen Diller Family Comprehensive Cancer Center, San Francisco (H.K.), David Geffen School of Medicine at UCLA, Los Angeles (J.W.G.), and Chao Family Comprehensive Cancer Center, University of California Irvine, Orange (V.W.Z.) - all in California; University of Michigan, Ann Arbor (F.W.), and START Midwest, Grand Rapids (N.L.) - both in Michigan; University of Pennsylvania, Philadelphia (M.B.); University of Chicago, Chicago (J.P.); Gustave Roussy, Villejuif (S.L.), Institut Bergonié, Bordeaux (Y.G.), Aix Marseille University, Centre National de la Recherche Scientifique, INSERM, Centre de Recherche en Cancérologie de Marseille, Assistance Publique-Hôpitaux de Marseille, Early Phase Cancer Trial Center CLIP2, Hospital La Timone, Marseille (F.B.), Centre Léon Bérard, Lyon (C.D.L.F.), and Hôpital Européen Georges-Pompidou, Faculté de Médecine Paris-Descartes, Paris (J.M.) - all in France; Mayo Clinic-Rochester, Rochester, MN (J.C.M.); Winship Cancer Institute of Emory University, Atlanta (T.K.O.); National Cancer Center Singapore, Singapore (D.S.W.T.); University of Bern, Bern, and Cantonal Hospital of Lucerne, Lucerne - both in Switzerland (O.G.); University of North Carolina-Chapel Hill, Chapel Hill (J.W.); University of Wisconsin-Carbone Cancer Center, Madison (M.E.B.); British Columbia Cancer Agency, Vancouver, Canada (J. Laskin); Oregon Health and Science University, Portland (M.H.T.); Universitätsklinikum Würzburg, Department of Internal Medicine I, Division of Endocrinology and Diabetology, Würzburg, Germany (M.K.); Sarah Cannon Research Institute-Tennessee Oncology, Nashville (T.M.B.); Johns Hopkins Kimmel Cancer Center, Washington, DC (B.L.); Fundación Jimenez Diaz, START-Madrid, Madrid (V.M.); Loxo Oncology, Stamford, CT (K.E., M.N., D.H., E.Y.Z., X.H., L.Y., J.K., S.M.R.); University of Texas M.D. Anderson Cancer Center, Houston (V.S., M.E.C.); and Ohio State University Comprehensive Cancer Center, Columbus (M.H.S.).

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http://dx.doi.org/10.1056/NEJMoa2005651DOI Listing
August 2020

Efficacy of Selpercatinib in Fusion-Positive Non-Small-Cell Lung Cancer.

N Engl J Med 2020 08;383(9):813-824

From Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College (A.D., E.R.) and New York University Langone Medical Center (V.V.), New York, and Roswell Park Comprehensive Cancer Center, Buffalo (G.K.D.) - all in New York; Dana-Farber Cancer Institute (G.R.O.) and Massachusetts General Hospital (J.G.), Boston; National Cancer Centre Singapore, Singapore (D.S.W.T.); the Chinese University of Hong Kong, Hong Kong, China (H.H.F.L.); Sarah Cannon Research Institute, Nashville (M.J.); University of California, San Francisco-Helen Diller Family Comprehensive Cancer Center, San Francisco (C.E.M.), University of California, San Diego, Moores Cancer Center, La Jolla (L.B.), and City of Hope Comprehensive Cancer Center, Duarte (K.L.R.) - all in California; University of Bern, Bern, and Cantonal Hospital of Lucerne, Lucerne - both in Switzerland (O.G.); Institut Gustave Roussy, Villejuif (B.B.), Hospital La Timone, Marseille (F.B.), and Centre Léon Bérard, Lyon (P.A.C.) - all in France; Severance Hospital, Yonsei University Health System (B.C.C.), and Samsung Medical Center, Sungkyunkwan University School of Medicine (K.P.), Seoul, and Seoul National University Bundang Hospital, Seongnam (Y.J.K.) - all in South Korea; Soroka University Medical Center, Beer-Sheva, Israel (N.P.); University of North Carolina-Chapel Hill, Chapel Hill (J. Weiss); National Cancer Center Hospital (Y.O.) and Cancer Institute Hospital of the Japanese Foundation for Cancer Research (M. Nishio), Tokyo, National Hospital Organization Kyushu Cancer Center, Fukuoka (T. Seto), Tottori University Hospital, Tottori (T. Sakamoto), Hyogo Cancer Center, Akashi (M.S.), Okayama University Hospital, Okayama (K.O.), and National Cancer Center Hospital East, Chiba (K.G.) - all in Japan; University of Chicago, Chicago (J.P.); the Ohio State University Comprehensive Cancer Center, Columbus (M.H.S.), and Cleveland Clinic, Cleveland (N.A.P.); Istituto Nazionale Tumori-National Cancer Institute, Università degli Studi di Milano, Milan (F.D.B.); Vall d'Hebron Institute of Oncology, Hospital Universitario Vall d'Hebron, Barcelona (E.G.); Center for Integrated Oncology, University Hospital of Cologne, Cologne, Germany (J. Wolf); Peter MacCallum Cancer Institute, Melbourne, VIC, Australia (B.S.); Sarah Cannon Research Institute at HealthONE, Denver (G.F.); Loxo Oncology, Stamford, CT (K.E., M. Nguyen, B.N., E.Y.Z., L.Y., X.H., E.O., S.M.R.); and the University of Texas M.D. Anderson Cancer Center, Houston (V.S.).

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http://dx.doi.org/10.1056/NEJMoa2005653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506467PMC
August 2020

Immune Oncology Biomarkers in Lung Cancer: an Overview.

Curr Oncol Rep 2020 Aug 15;22(11):107. Epub 2020 Aug 15.

CNRS, INSERM, CRCM, APHM, Multidisciplinary Oncology & Therapeutic Innovations Department, Aix Marseille University, Marseille, France.

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http://dx.doi.org/10.1007/s11912-020-00970-3DOI Listing
August 2020

Like a Rolling Stone: Sting-Cgas Pathway and Cell-Free DNA as Biomarkers for Combinatorial Immunotherapy.

Pharmaceutics 2020 Aug 11;12(8). Epub 2020 Aug 11.

SMARTc Unit, CRCM Inserm U1068, Aix Marseille University, 13007 Marseille, France.

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http://dx.doi.org/10.3390/pharmaceutics12080758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464249PMC
August 2020

COVID-19 management in a cancer center: the ICU storm.

Support Care Cancer 2020 Oct 31;28(10):5037-5044. Epub 2020 Jul 31.

Interdisciplinary Cancer Course Department (DIOPP), Gustave Roussy Cancer Campus, Villejuif, France.

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http://dx.doi.org/10.1007/s00520-020-05658-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392620PMC
October 2020

Older Patients Treated for Lung and Thoracic Cancers: Unplanned Hospitalizations and Overall Survival.

Clin Lung Cancer 2020 Jun 12. Epub 2020 Jun 12.

Multidisciplinary Oncology and Therapeutic Innovations Department, AP-HM, Marseille, France; Aix-Marseille University, CNRS, INSERM, CRCM, Marseille, France.

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http://dx.doi.org/10.1016/j.cllc.2020.06.004DOI Listing
June 2020

Deciphering the response and resistance to immune-checkpoint inhibitors in lung cancer with artificial intelligence-based analysis: when PIONeeR meets QUANTIC.

Br J Cancer 2020 Aug 16;123(3):337-338. Epub 2020 Jun 16.

Centre de Recherche en Cancérologie de Marseille, Aix-Marseille Université, Inserm U1068, CNRS UMR 7258, Institut Paoli Calmettes, 13009, Marseille, France.

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http://dx.doi.org/10.1038/s41416-020-0918-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403333PMC
August 2020

TERAVOLT: Thoracic Cancers International COVID-19 Collaboration.

Cancer Cell 2020 06 16;37(6):742-745. Epub 2020 May 16.

Department of Medicine, Division of Hematology & Oncology, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2020.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229923PMC
June 2020

Chemotherapy and immune checkpoint inhibitor combination, a new standard in squamous non-small cell lung cancer?

Transl Lung Cancer Res 2020 Apr;9(2):401-405

Multidisciplinar Oncology & Therapeutic Innovations Department, Aix Marseille University, CNRS, INSERM, CRCM, APHM, Marseille, France.

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http://dx.doi.org/10.21037/tlcr.2020.02.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225151PMC
April 2020

Real-world assessment of the BRAF status in non-squamous cell lung carcinoma using VE1 immunohistochemistry: A single laboratory experience (LPCE, Nice, France).

Lung Cancer 2020 07 5;145:58-62. Epub 2020 May 5.

Laboratory of Clinical and Experimental Pathology, Pasteur Hospital, University Côte d'Azur, 30 avenue de la voie romaine, 06000, Nice, France; Hospital-related Biobank (BB-0033-00025), Pasteur Hospital, University Côte d'Azur, 30 avenue de la voie romaine, 06000, Nice, France; FHU OncoAge, Pasteur Hospital, University Côte d'Azur, 30 avenue de la voie romaine, 06000, Nice, France; IRCAN Inserm 1081/CNRS 7283, Antoine Lacassagne Center, avenue de valombrose, 06002, Nice, France. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2020.04.024DOI Listing
July 2020

Challenges in lung cancer therapy during the COVID-19 pandemic.

Lancet Respir Med 2020 06 9;8(6):542-544. Epub 2020 Apr 9.

Center for Immuno-Oncology, Medical Oncology and Immunotherapy, Department of Oncology, University Hospital of Siena, 53100 Siena, Italy; NIBIT Foundation Onlus, Siena, Italy. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(20)30170-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146673PMC
June 2020

Non-small-cell lung cancer brain metastases and PD-(L)1 immune checkpoint inhibitors.

Lancet Oncol 2020 05 3;21(5):607-608. Epub 2020 Apr 3.

Aix Marseille University, CNRS, INSERM, CRCM, Marseille, France; Aix Marseille University, APHM, Marseille, France.

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http://dx.doi.org/10.1016/S1470-2045(20)30207-2DOI Listing
May 2020

Illness representations and quality of life in French patients suffering from lung cancer.

Psychol Health Med 2020 Oct 17;25(9):1119-1129. Epub 2020 Feb 17.

Service d'Oncologie Multidisciplinaire et Innovations Thérapeutiques, APHM-Nord , Marseille, France.

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http://dx.doi.org/10.1080/13548506.2020.1728349DOI Listing
October 2020

Lorlatinib: an additional option for ALK-positive non-small cell lung cancer?

Transl Lung Cancer Res 2019 Dec;8(Suppl 4):S383-S386

Department of Multidisciplinary Oncology & Therapeutic Innovations, Aix Marseille University, CNRS, INSERM, CRCM, APHM, Marseille, France.

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http://dx.doi.org/10.21037/tlcr.2019.05.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987344PMC
December 2019

Efficacy of Immune Checkpoint Inhibitors in Lung Sarcomatoid Carcinoma.

J Thorac Oncol 2020 05 25;15(5):860-866. Epub 2020 Jan 25.

Department of Thoracic Oncology, AP-HP, Groupe Hospitalier HUPC, Hôpital Cochin, Paris, France; Centre de Recherche des Cordeliers, Université Paris Descartes, Complement, Inflammation and Cancer, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2020.01.014DOI Listing
May 2020

Nivolumab plus Ipilimumab in Advanced Non-Small-Cell Lung Cancer.

N Engl J Med 2019 11 28;381(21):2020-2031. Epub 2019 Sep 28.

From the Memorial Sloan Kettering Cancer Center, New York (M.D.H.); Hospital Universitario Doce de Octubre, Centro Nacional de Investigaciones Oncológicas, Universidad Complutense, and Centro de Investigación Biomédica en Red de Cáncer, Madrid (L.P.-A.), Hospital Universitario Virgen Del Rocio, Seville (R.B.C.), and the Catalan Institute of Oncology-Germans Trias i Pujol Hospital, Badalona (E.C.C.) - all in Spain; Ambulatorium Chemioterapii, Bydgoszcz, Poland (B.Z.); the Asan Medical Center (S.-W.K.) and the Samsung Medical Center at Sungkyunkwan University School of Medicine (K.P.) - both in Seoul, South Korea; the Institute of Oncology Prof. Dr. Alexandru Trestioreanu, Bucharest, Romania (A.A.); the Hospital Italiano de Buenos Aires, Buenos Aires (L.L.); Instituto Jalisciense de Cancerologia, Guadalajara, Mexico (E.M.J.); the Saitama Cancer Center, Saitama, Japan (H.S.); Matrai Gyogyintezet, Matrahaza, Hungary (I.A.); Limoges University Hospital, Limoges (A.V.), and Aix-Marseille University, National Center for Scientific Research, INSERM, Centre de Recherche en Cancérologie de Marseille, Assistance Publique-Hôpitaux de Marseille, Marseille (F.B.) - all in France; Centre Hospitalier Universitaire Vaudois, Lausanne University, Lausanne, Switzerland (S.P.); Sotiria General Hospital, National and Kapodistrian University of Athens, Athens (K.S.); Lung Clinic Grosshansdorf, Airway Research Center North, German Center of Lung Research, Grosshansdorf, Germany (M.R.); Fox Chase Cancer Center, Philadelphia (H.B.); Johns Hopkins Kimmel Cancer Center, Baltimore (J.R.B.); Princess Alexandra Hospital, Brisbane, QLD, Australia (K.J.O.); Bristol-Myers Squibb, Princeton, NJ (W.J.G., P.B., S.K.R., R.S.K., F.E.N.); and Winship Cancer Institute, Emory University, Atlanta (S.S.R.).

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http://dx.doi.org/10.1056/NEJMoa1910231DOI Listing
November 2019

Critical Assessment in Routine Clinical Practice of Liquid Biopsy for EGFR Status Testing in Non-Small-Cell Lung Cancer: A Single-Laboratory Experience (LPCE, Nice, France).

Clin Lung Cancer 2020 01 3;21(1):56-65.e8. Epub 2019 Aug 3.

Institute of Research on Cancer and Ageing of Nice (IRCAN), Inserm U1081, CNRS UMR7284, Team 4, Université Côte d'Azur, CHU de Nice, Nice, France; Laboratory of Clinical and Experimental Pathology (LPCE), Université Côte d'Azur, CHU de Nice, University Hospital Federation OncoAge, Nice, France; Hospital-Integrated Biobank (BB-0033-00025), Université Côte d'Azur, CHU de Nice, University Hospital Federation OncoAge, Hospital-Integrated Biobank (BB-0033-00025), Nice, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15257304193021
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http://dx.doi.org/10.1016/j.cllc.2019.07.010DOI Listing
January 2020

First-line immune checkpoint blockade for advanced non-small-cell lung cancer: Travelling at the speed of light.

Lung Cancer 2019 08 19;134:245-253. Epub 2019 Jun 19.

Department of Medical Oncology, The Christie NHS Foundation Trust, Manchester, United Kingdom; Department of Medical Oncology, Manchester University NHS Foundation Trust, Manchester, United Kingdom; Division of Cancer Sciences, University of Manchester, Manchester, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2019.06.007DOI Listing
August 2019

Companion diagnostic tests for treatment of lung cancer patients: what are the current and future challenges?

Expert Rev Mol Diagn 2019 05 6;19(5):429-438. Epub 2019 May 6.

b CRCM, INSERM, CNRS, AP-HM, Multidisciplinary Oncology and Therapeutic Innovations Department , Aix Marseille University , Marseille , France.

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http://dx.doi.org/10.1080/14737159.2019.1611426DOI Listing
May 2019

Functional status in a geriatric oncology setting: A review.

J Geriatr Oncol 2019 11 27;10(6):884-894. Epub 2019 Feb 27.

Department of Geriatrics, Geriatric Oncology Unit, APHP, Hospital European Georges Pompidou, Paris, France; Clinical Epidemiology and Ageing Unit, EA, 7376, Universite' Paris-Est, Creteil, France.

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http://dx.doi.org/10.1016/j.jgo.2019.02.004DOI Listing
November 2019

[Tumor banks and complex data management: Current and future challenges].

Ann Pathol 2019 Apr 25;39(2):137-143. Epub 2019 Feb 25.

Inserm, Inra, nutrition métabolismes et cancer, CRB-Santé, université de Rennes, rue Henri-Le-Guilloux, 35033 Rennes, France.

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http://dx.doi.org/10.1016/j.annpat.2019.01.017DOI Listing
April 2019

Alectinib in the treatment of ALK-positive metastatic non-small cell lung cancer: clinical trial evidence and experience with a focus on brain metastases.

Ther Adv Respir Dis 2019 Jan-Dec;13:1753466619831906

Service d'Oncologie Multidisciplinaire et Innovations Thérapeutiques, Hôpital Nord, Chemin des Bourrely, 13915 Marseille Cedex, FranceAix Marseille University, APHM, CNRS, INSERM, CRCM, Hôpital Nord, Oncologie Multidisciplinaire et Innovations Thérapeutiques, Marseille, France.

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http://dx.doi.org/10.1177/1753466619831906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385324PMC
August 2019

Efficacy of Immune Checkpoint Inhibitors in KRAS-Mutant Non-Small Cell Lung Cancer (NSCLC).

J Thorac Oncol 2019 06 6;14(6):1095-1101. Epub 2019 Feb 6.

Aix Marseille University, Assistance Publique Hôpitaux de Marseille, Department of Multidisciplinary Oncology and Therapeutic Innovations. Marseille, France; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm UMR1068, CNRS UMR7258, Marseille, France.

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http://dx.doi.org/10.1016/j.jtho.2019.01.011DOI Listing
June 2019

Efficacy and safety of nivolumab in patients with non-small cell lung cancer: a retrospective study in clinical practice.

J Chemother 2019 Apr 30;31(2):90-94. Epub 2018 Dec 30.

c Oncologie multidisciplinaire et innovations thérapeutiques , AP-HM , Marseille , France.

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http://dx.doi.org/10.1080/1120009X.2018.1551753DOI Listing
April 2019

"I think it's a bit early for now": impact of psychological factors on drafting advance directives among cancer patients.

J Psychosoc Oncol 2019 Jan-Feb;37(1):37-49. Epub 2018 Dec 26.

b Aix Marseille Univ, LPS , Aix-en-Provence , France.

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http://dx.doi.org/10.1080/07347332.2018.1541494DOI Listing
February 2020

The clinical utility of tumor mutational burden in non-small cell lung cancer.

Transl Lung Cancer Res 2018 Dec;7(6):639-646

Aix Marseille University, Assistance Publique Hôpitaux de Marseille, Multidisciplinary Oncology & Therapeutic Innovations department, Marseille, France.

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http://tlcr.amegroups.com/article/view/24870/18841
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http://dx.doi.org/10.21037/tlcr.2018.10.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249623PMC
December 2018

Therapeutic potential of trametinib to inhibit the mutagenesis by inactivating the protein kinase pathway in non-small cell lung cancer.

Expert Rev Anticancer Ther 2019 01 4;19(1):11-17. Epub 2018 Dec 4.

a Assistance Publique Hôpitaux de Marseille, Multidisciplinary Oncology & Therapeutic Innovations dpt , Aix Marseille University , Marseille , France.

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http://dx.doi.org/10.1080/14737140.2019.1554440DOI Listing
January 2019

Association Between Immune-related Adverse Events and Efficacy of Immune Checkpoint Inhibitors in Non-small-cell Lung Cancer.

Clin Lung Cancer 2019 05 11;20(3):201-207. Epub 2018 Oct 11.

Multidisciplinary Oncology and Therapeutic Innovations Department, Aix Marseille University, Assistance Publique Hôpitaux de Marseille, Marseille, France; Aix Marseille University, Inserm U911 CRO2, Marseille, France.

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https://linkinghub.elsevier.com/retrieve/pii/S15257304183026
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http://dx.doi.org/10.1016/j.cllc.2018.10.002DOI Listing
May 2019

Pemetrexed Continuation Maintenance Phase 3 Trials in Nonsquamous, Non-Small-Cell Lung Cancer: Focus on 2-Year Overall Survival and Continuum of Care.

Clin Lung Cancer 2018 11 26;19(6):e823-e830. Epub 2018 May 26.

Oncology at Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN.

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http://dx.doi.org/10.1016/j.cllc.2018.05.013DOI Listing
November 2018

Specialists to the Rescue of Oncologists for the Management of Toxicity Occurring Under Combination of Anticancer Therapies.

J Thorac Oncol 2018 11;13(11):e231-e232

Marseille Early Phases Cancer Center CLIP2, and Department of Nephrology and Kidney Transplantation, Assistance Publique Hôpitaux de Marseille, Aix Marseille University, Marseille, France.

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https://linkinghub.elsevier.com/retrieve/pii/S15560864183077
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http://dx.doi.org/10.1016/j.jtho.2018.07.003DOI Listing
November 2018

Immunologically effective dose: a practical model for immuno-radiotherapy.

Oncotarget 2018 Aug 7;9(61):31812-31819. Epub 2018 Aug 7.

Simulation & Modelling Adaptive Response for Therapeutics in Cancer (SMARTc), Center for Research on Cancer of Marseille, CRCM Inserm UMR1068, CNRS UMR7258, Aix Marseille Université U105, Institut Paoli Calmettes, Marseille, France.

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http://www.oncotarget.com/fulltext/25746
Publisher Site
http://dx.doi.org/10.18632/oncotarget.25746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112752PMC
August 2018

Phase Ib/II study of the pan-cyclin-dependent kinase inhibitor roniciclib in combination with chemotherapy in patients with extensive-disease small-cell lung cancer.

Lung Cancer 2018 09 27;123:14-21. Epub 2018 Apr 27.

Aix Marseille University, Jardin du Pharo, 58, bd Charles Livon, 13284 Marseille, France; Assistance Publique Hôpitaux de Marseille, 80, rue Brochier, 13005 Marseille, France; Centre d'Essais Précoces en Cancérologie de Marseille (CLIP(2)), Hôpital La Timone - Basement F, 1st Floor, 264, rue St Pierre, 13885 Marseille, France. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2018.04.022DOI Listing
September 2018

Lamins in Lung Cancer: Biomarkers and Key Factors for Disease Progression through miR-9 Regulation?

Cells 2018 Jul 16;7(7). Epub 2018 Jul 16.

Aix Marseille Université, APHM, INSERM, MMG, Hôpital la Timone, Service de Biologie Cellulaire, 13385 Marseille, France.

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http://dx.doi.org/10.3390/cells7070078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071028PMC
July 2018

Another Drawback for Clinical Trials Entry Criteria.

J Thorac Oncol 2018 07;13(7):e116-e117

Aix Marseille University, Assistance Publique Hopitaux de Marseille, Marseille, France.

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http://dx.doi.org/10.1016/j.jtho.2018.02.007DOI Listing
July 2018

Cost-effectiveness of biomarker testing for treatment choices in advanced non-small cell lung carcinoma: impact of diagnostic strategies and their turnaround times.

Eur Respir J 2018 06 21;51(6). Epub 2018 Jun 21.

Assistance Publique Hôpitaux de Paris, Hôpital Tenon, Service de Pneumologie, Sorbonne Universités, UPMC Univ Paris 06, GRC n04, Theranoscan, Paris, France.

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http://dx.doi.org/10.1183/13993003.00844-2018DOI Listing
June 2018

Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC.

N Engl J Med 2018 Jun 4;378(24):2288-2301. Epub 2018 Jun 4.

From the Florida Hospital Cancer Institute, Orlando (M.A.S.); Rocky Mountain Cancer Centers, Denver (R.M.J.); US Oncology, Houston (R.M.J.); Azienda Unità Sanitaria Locale della Romagna, Ravenna, Italy (F.C.); Instituto Nacional del Torax, Santiago, Chile (F.O.); Moscow City Oncology Hospital, Moscow (D.S.); National Hospital Organization Shikoku Cancer Center, Matsuyama, Japan (N.N.); Complejo Hospitalario Universitario Insular Materno-Infantil de Gran Canaria, Universidad de Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain (D.R.-A.); Centre Hospitalier Universitaire de Grenoble Alpes, Grenoble (D.M.-S.), and Aix Marseille University, Assistance Publique-Hôpitaux de Marseille, Marseille (F.B.) - both in France; New England Cancer Specialists, Scarborough, ME (C.A.T.); Allegheny Health Network Cancer Institute, Pittsburgh (G.F.); Genentech, South San Francisco, CA (C.K., A.L., S.C., Y.D., Y.S., M.K., A.L.-C., A.S.); and Lung Clinic Grosshansdorf, Airway Research Center North, German Center of Lung Research, Grosshansdorf, Germany (M.R.).

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http://www.nejm.org/doi/10.1056/NEJMoa1716948
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http://dx.doi.org/10.1056/NEJMoa1716948DOI Listing
June 2018

Durvalumab after chemoradiotherapy in stage III non-small cell lung cancer.

J Thorac Dis 2018 Apr;10(Suppl 9):S1032-S1036

Aix Marseille University, Assistance Publique Hôpitaux de Marseille, Multidisciplinary Oncology & Therapeutic Innovations dpt, Marseille, France.

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http://jtd.amegroups.com/article/view/20558/15912
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http://dx.doi.org/10.21037/jtd.2018.04.61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949420PMC
April 2018

Drug repurposing in malignant pleural mesothelioma: a breath of fresh air?

Eur Respir Rev 2018 Mar 14;27(147). Epub 2018 Mar 14.

Aix Marseille University, Assistance Publique Hôpitaux de Marseille, Multidisciplinary Oncology and Therapeutic Innovations Dept, Marseille, France

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http://dx.doi.org/10.1183/16000617.0098-2017DOI Listing
March 2018

Atezolizumab: feasible second-line therapy for patients with non-small cell lung cancer? A review of efficacy, safety and place in therapy.

Ther Adv Med Oncol 2017 Dec 19;9(12):769-779. Epub 2017 Dec 19.

Service d'Oncologie Multidisciplinaire & Innovations Thérapeutiques, Pôle Cardio-Vasculaire et Thoracique, Aix Marseille University, Assistance Publique - Hôpitaux de Marseille Hôpital Nord - Chemin des Bourrely, 13915 Marseille Cedex 20, France.

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http://dx.doi.org/10.1177/1758834017741074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808842PMC
December 2017

Clustering based on unsupervised binary trees to define subgroups of cancer patients according to symptom severity in cancer.

Qual Life Res 2018 02 8;27(2):555-565. Epub 2017 Dec 8.

EA3279 Self-perceived Health Assessment Research Unit and Department of Public Health, APHM, Aix-Marseille University, 27 bd Jean Moulin, 13385, Marseille, France.

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http://dx.doi.org/10.1007/s11136-017-1760-9DOI Listing
February 2018

Personalised medicine for nonsmall cell lung cancer.

Eur Respir Rev 2017 Dec 15;26(146). Epub 2017 Nov 15.

Aix Marseille University, Assistance Publique Hôpitaux de Marseille, Multidisciplinary Oncology and Therapeutic Innovations Dept, Marseille, France.

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http://dx.doi.org/10.1183/16000617.0066-2017DOI Listing
December 2017

Nivolumab Versus Docetaxel in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer: Two-Year Outcomes From Two Randomized, Open-Label, Phase III Trials (CheckMate 017 and CheckMate 057).

J Clin Oncol 2017 Dec 12;35(35):3924-3933. Epub 2017 Oct 12.

Leora Horn, Vanderbilt-Ingram Cancer Center; David R. Spigel, Sarah Cannon Research Institute/Tennessee Oncology, Nashville, TN; Everett E. Vokes, University of Chicago, Chicago, IL; Esther Holgado, Hospital De Madrid, Norte Sanchinarro, Madrid; Enriqueta Felip, Hospital Universitari Vall d'Hebron, Barcelona; Luis Paz-Ares, Hospital Universitario Virgen Del Rocio, Seville, Spain; Neal Ready, Duke University Medical Center, Durham, NC; Martin Steins, Thoraxklinik-Heidelberg gGmbH, Heidelberg; Martin Kohlhäeufl, Robert-Bosch-Krankenhaus, Stuttgart; Martin Reck, LungenClinic Grosshansdorf, Airway Research Center North, German Center for Lung Research, Grosshansdorf; Wilfried E.E. Eberhardt, University Hospital and Ruhrlandclinic, University of Duisburg-Essen, Essen, Germany; Elena Poddubskaya, N.N. Blokhin Russian Cancer Research Center, Moscow, Russia; Hossein Borghaei, Fox Chase Cancer Center, Philadelphia, PA; Adam Pluzanski, Centrum Onkologii-Instytut Im. Marii Sklodowskiej-Curie, Warsaw, Poland; Karen L. Reckamp, City of Hope, Duarte, CA; Marco A. Burgio and Lucio Crinò, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Scientifico Romagnolo Per lo Studio e la Cura dei Tumori, Meldola, Italy; David Waterhouse, Oncology Hematology Care (OHC)/US Oncology, Cincinnati, OH; Fabrice Barlesi, Aix-Marseille Université, Assistance Publique Hôpitaux de Marseille, Marseille; Jérôme Fayette, Léon Bérard, Lyon, France; Scott Antonia, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Oscar Arrieta, Instituto Nacional De Cancerologia, Mexico City, Mexico; Naiyer Rizvi and Matthew D. Hellmann, Memorial Sloan Kettering Cancer Center, New York, NY; William J. Geese, Ang Li, Anne Blackwood-Chirchir, and Diane Healey, Bristol-Myers Squibb, Princeton, NJ; and Julie Brahmer, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD.

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http://dx.doi.org/10.1200/JCO.2017.74.3062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075826PMC
December 2017

Dyadic effects of coping strategies, time perspectives, and personality on the quality of life of cancer patients and their caregivers.

Psychooncology 2018 02 6;27(2):590-599. Epub 2017 Oct 6.

EA3279, Self-perceived Health Assessment Research Unit, Aix Marseille Université, Marseille, France.

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http://dx.doi.org/10.1002/pon.4553DOI Listing
February 2018

Phase III Trial of Ipilimumab Combined With Paclitaxel and Carboplatin in Advanced Squamous Non-Small-Cell Lung Cancer.

J Clin Oncol 2017 Oct 30;35(30):3449-3457. Epub 2017 Aug 30.

Ramaswamy Govindan, Washington University School of Medicine, St Louis, MO; Aleksandra Szczesna, Mazowieckie Centrum Leczenia Chorób Płuc i Gruźlicy, Otwock; Jacek Jassem, Medical University of Gdansk, Gdansk, Poland; Myung-Ju Ahn, Samsung Medical Center, Sungkyunkwan University, Seoul; Ki Hyeong Lee, Chungbuk National University Hospital, Cheongju-si, Republic of Korea; Claus-Peter Schneider, Zentralklinik Bad Berka, Bad Berka; Joachim Von Pawel, Asklepius Fachkliniken, Gauting; Martin Reck, LungenClinic Grosshansdorf, Airway Research Center North, German Center for Lung Research, Grosshansdorf, Germany; Pablo Fernando Gonzalez Mella, Centro de Investigaciones Clinicas, Universidad de Valparaíso and Fundación Arturo López Pérez, Santiago, Chile; Fabrice Barlesi, Aix Marseille University, Assistance Publique-Hôpitaux de Marseille, Marseille, France; Baohui Han, Shanghai Chest Hospital Affiliated to Shanghai JiaoTong University, Shanghai; Li Zhang, Sun Yat-Sen University Cancer Center, Guangzhou, People's Republic of China; Doina Elena Ganea, Spitalul Judetean De Urgenta Suceava, Sfântul loan cel Nou, Suceava, Romania; Vladimir Vladimirov, State Healthcare Institute, Pyatigorsk Oncology Dispensary, Pyatigorsk; Natalia Fadeeva, Chelyabinsk Regional Oncology Dispensary, Chelyabinsk, Russian Federation; Takayasu Kurata, Kansai Medical University Hirakata Hospital, Osaka; Tomohide Tamura, St Luke's International Hospital, Tokyo, Japan; Pieter E. Postmus, University of Liverpool, Liverpool, United Kingdom; Kenneth O'Byrne, Princess Alexandra Hospital and Queensland University of Technology, Brisbane, Queensland, Australia; and Justin Kopit, Mingshun Li, and Marina Tschaika, Bristol-Myers Squibb, Princeton, NJ.

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http://ascopubs.org/doi/10.1200/JCO.2016.71.7629
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http://dx.doi.org/10.1200/JCO.2016.71.7629DOI Listing
October 2017