Publications by authors named "Fabio Malavasi"

142Publications

Comparison of CD38 antibodies in vitro and ex vivo mechanisms of action in multiple myeloma.

Authors:
Michelle Kinder Nizar J Bahlis Fabio Malavasi Bart De Goeij Alexander Babich Jocelyn Sendecki Joshua Rusbuldt Kevin Bellew Colleen Kane Niels W C J Van de Donk

Haematologica 2021 Jan 14. Epub 2021 Jan 14.

Department of Hematology, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam.

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January 2021

PD-L1/PD-1 Axis in Multiple Myeloma Microenvironment and a Possible Link with CD38-Mediated Immune-Suppression.

Authors:
Federica Costa Valentina Marchica Paola Storti Fabio Malavasi Nicola Giuliani

Cancers (Basel) 2021 Jan 6;13(2). Epub 2021 Jan 6.

Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.

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January 2021

Novel Insights in Anti-CD38 Therapy Based on CD38-Receptor Expression and Function: The Multiple Myeloma Model.

Authors:
Beatrice Anna Zannetti Angelo Corso Faini Evita Massari Massimo Geuna Enrico Maffini Giovanni Poletti Claudio Cerchione Giovanni Martinelli Fabio Malavasi Francesco Lanza

Cells 2020 12 11;9(12). Epub 2020 Dec 11.

Hematology Unit and Romagna Transplant Network, Ravenna Hospital, 48121 Ravenna, Italy.

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December 2020

CXCR4 Inhibition Counteracts Immunosuppressive Properties of Metastatic NSCLC Stem Cells.

Authors:
Orazio Fortunato Dimas Carolina Belisario Mara Compagno Francesca Giovinazzo Cristiano Bracci Ugo Pastorino Alberto Horenstein Fabio Malavasi Riccardo Ferracini Stefania Scala Gabriella Sozzi Luca Roz Ilaria Roato Giulia Bertolini

Front Immunol 2020 2;11:02168. Epub 2020 Oct 2.

Tumor Genomics Unit, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Nazionale dei Tumori, Milan, Italy.

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October 2020

The Circular Life of Human CD38: From Basic Science to Clinics and Back.

Authors:
Alberto L Horenstein Angelo C Faini Fabio Morandi Cristiano Bracci Francesco Lanza Nicola Giuliani Aneel Paulus Fabio Malavasi

Molecules 2020 Oct 21;25(20). Epub 2020 Oct 21.

Dipartimento Scienze Mediche, Università di Torino, Centro Ricerche Medicina Sperimentale (CeRMS) and Fondazione Ricerca Molinette Onlus, 10121 Torino, Italy.

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October 2020

Immunohistochemical scoring of CD38 in the tumor microenvironment predicts responsiveness to anti-PD-1/PD-L1 immunotherapy in hepatocellular carcinoma.

Authors:
Harry Ho Man Ng Ren Yuan Lee Siting Goh Isabel Shu Ying Tay Xinru Lim Bernett Lee Valerie Chew Huihua Li Benedict Tan Sherlly Lim Jeffrey Chun Tatt Lim Bijin Au Josh Jie Hua Loh Sahil Saraf John Edward Connolly Tracy Loh Wei Qiang Leow Joycelyn Jie Xin Lee Han Chong Toh Fabio Malavasi Ser Yee Lee Pierce Chow Evan W Newell Su Pin Choo David Tai Joe Yeong Tony Kiat Hon Lim

J Immunother Cancer 2020 Aug;8(2)

Division of Pathology, Singapore General Hospital, Singapore

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August 2020

CD38 and Anti-CD38 Monoclonal Antibodies in AL Amyloidosis: Targeting Plasma Cells and beyond.

Authors:
Dario Roccatello Roberta Fenoglio Savino Sciascia Carla Naretto Daniela Rossi Michela Ferro Antonella Barreca Fabio Malavasi Simone Baldovino

Int J Mol Sci 2020 Jun 10;21(11). Epub 2020 Jun 10.

Nephrology and Dialysis Unit & CMID (Center of Research of Immunopathology and Rare Diseases), Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, San Giovanni Bosco Hub Hospital of Turin, and Department of Clinical and Biological Sciences, University of Turin, 10154 Turin, Italy.

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June 2020

Targeting CD38 is lethal to Breg-like chronic lymphocytic leukemia cells and Tregs, but restores CD8+ T-cell responses.

Authors:
Alak Manna Timothy Kellett Sonikpreet Aulakh Laura J Lewis-Tuffin Navnita Dutta Keith Knutson Eduardo Chini Javier Pinilla-Ibarz Nicole Lamanna Rami Manochakian Fabio Malavasi Taimur Sher Asher A Chanan-Khan Sikander Ailawadhi Aneel Paulus

Blood Adv 2020 05;4(10):2143-2157

Department of Cancer Biology, Mayo Clinic, Jacksonville, FL.

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May 2020

Neutralization of extracellular NAMPT (nicotinamide phosphoribosyltransferase) ameliorates experimental murine colitis.

Authors:
Giorgia Colombo Nausicaa Clemente Andrea Zito Cristiano Bracci Federico Simone Colombo Sabina Sangaletti Elena Jachetti Davide Giuseppe Ribaldone Gian Paolo Caviglia Luca Pastorelli Marco De Andrea Samuele Naviglio Marianna Lucafò Gabriele Stocco Ambra A Grolla Michela Campolo Giovanna Casili Salvatore Cuzzocrea Emanuela Esposito Fabio Malavasi Armando A Genazzani Chiara Porta Cristina Travelli

J Mol Med (Berl) 2020 04 27;98(4):595-612. Epub 2020 Apr 27.

Department of Pharmaceutical Sciences, Università degli Studi di Pavia, 27100, Pavia, Italy.

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April 2020

CD14 CD16 monocytes are involved in daratumumab-mediated myeloma cells killing and in anti-CD47 therapeutic strategy.

Authors:
Paola Storti Rosanna Vescovini Federica Costa Valentina Marchica Denise Toscani Benedetta Dalla Palma Luisa Craviotto Fabio Malavasi Nicola Giuliani

Br J Haematol 2020 Aug 12;190(3):430-436. Epub 2020 Mar 12.

Department of Medicine and Surgery, University of Parma, Parma, Italy.

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August 2020

CD22 Expression in B-Cell Acute Lymphoblastic Leukemia: Biological Significance and Implications for Inotuzumab Therapy in Adults.

Authors:
Francesco Lanza Enrico Maffini Michela Rondoni Evita Massari Angelo Corso Faini Fabio Malavasi

Cancers (Basel) 2020 Jan 28;12(2). Epub 2020 Jan 28.

Department of Medical Science, University of Torino and Fondazione Ricerca Molinette, 10126 Torino, Italy.

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January 2020

The CD38/NAD/SIRTUIN1/EZH2 Axis Mitigates Cytotoxic CD8 T Cell Function and Identifies Patients with SLE Prone to Infections.

Authors:
Eri Katsuyama Abel Suarez-Fueyo Sean J Bradley Masayuki Mizui Ana V Marin Lama Mulki Suzanne Krishfield Fabio Malavasi Joon Yoon Shannan J Ho Sui Vasileios C Kyttaris George C Tsokos

Cell Rep 2020 01;30(1):112-123.e4

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. Electronic address:

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January 2020

Expression of CD38 on Macrophages Predicts Improved Prognosis in Hepatocellular Carcinoma.

Authors:
Jian Hang Lam Harry Ho Man Ng Chun Jye Lim Xin Ni Sim Fabio Malavasi Huihua Li Josh Jie Hua Loh Khin Sabai Joo-Kyung Kim Clara Chong Hui Ong Tracy Loh Wei Qiang Leow Su Pin Choo Han Chong Toh Ser Yee Lee Chung Yip Chan Valerie Chew Tong Seng Lim Joe Yeong Tony Kiat Hon Lim

Front Immunol 2019 4;10:2093. Epub 2019 Sep 4.

Division of Pathology, Singapore General Hospital, Singapore, Singapore.

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November 2020

Editorial: Immunotherapy in Multiple Myeloma.

Authors:
Nicola Giuliani Fabio Malavasi

Front Immunol 2019 14;10:1945. Epub 2019 Aug 14.

Department of Medical Science, University of Turin and "Fondazione Ricerca Molinette", Turin, Italy.

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October 2020

Novel targets for the treatment of relapsing multiple myeloma.

Authors:
Nicola Giuliani Fabrizio Accardi Valentina Marchica Benedetta Dalla Palma Paola Storti Denise Toscani Emanuela Vicario Fabio Malavasi

Expert Rev Hematol 2019 07 3;12(7):481-496. Epub 2019 Jun 3.

b Department of Medical Science , University of Turin , Turin , Italy.

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July 2019

Microvesicles expressing adenosinergic ectoenzymes and their potential role in modulating bone marrow infiltration by neuroblastoma cells.

Authors:
Fabio Morandi Danilo Marimpietri Alberto L Horenstein Maria Valeria Corrias Fabio Malavasi

Oncoimmunology 2019;8(5):e1574198. Epub 2019 Feb 19.

Department of Medical Sciences, Laboratory of Immunogenetics, University of Torino, Torino, Italy.

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February 2019

CD38 in Adenosinergic Pathways and Metabolic Re-programming in Human Multiple Myeloma Cells: In-tandem Insights From Basic Science to Therapy.

Authors:
Alberto L Horenstein Cristiano Bracci Fabio Morandi Fabio Malavasi

Front Immunol 2019 24;10:760. Epub 2019 Apr 24.

Laboratory of Immunogenetics, Department of Medical Sciences, Turin, Italy.

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October 2020

Immunotherapy in Multiple Myeloma: Accelerating on the Path to the Patient.

Authors:
Irene Ghobrial Calixto Hernández Cruz Alfred Garfall Nina Shah Nikhil Munshi Jonathan Kaufman Lawrence H Boise Gareth Morgan Viktor A Adalsteinsson Salomon Manier Rathi Pillai Fabio Malavasi Sagar Lonial

Clin Lymphoma Myeloma Leuk 2019 06 20;19(6):332-344. Epub 2019 Feb 20.

Winship Cancer Institute of Emory University, Atlanta, GA. Electronic address:

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June 2019

Targeting CD38 Enhances the Antileukemic Activity of Ibrutinib in Chronic Lymphocytic Leukemia.

Authors:
Alak Manna Sonikpreet Aulakh Prachi Jani Salman Ahmed Sharoon Akhtar Marie Coignet Michael Heckman Zahara Meghji Kirtipal Bhatia Aarushi Sharma Taimur Sher Victoria Alegria Fabio Malavasi Eduardo N Chini Asher Chanan-Khan Sikander Ailawadhi Aneel Paulus

Clin Cancer Res 2019 07 2;25(13):3974-3985. Epub 2019 Apr 2.

Department of Cancer Biology, Mayo Clinic, Jacksonville, Florida.

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July 2019

Mechanism of Action of a New Anti-CD38 Antibody: Enhancing Myeloma Immunotherapy.

Authors:
Fabio Malavasi Angelo Corso Faini

Clin Cancer Res 2019 05 7;25(10):2946-2948. Epub 2019 Mar 7.

MD/PhD Special Program, School of Medicine, University of Torino, Torino, Italy.

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May 2019