Publications by authors named "Fabio Di Lisa"

90Publications

The energetic cost of NNT-dependent ROS removal.

J Biol Chem 2020 Nov;295(48):16217-16218

Neuroscience Institute, National Research Council of Italy (CNR), Padova, Italy

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November 2020

Effects of air pollution particles (ultrafine and fine particulate matter) on mitochondrial function and oxidative stress - Implications for cardiovascular and neurodegenerative diseases.

Arch Biochem Biophys 2020 12 5;696:108662. Epub 2020 Nov 5.

Department of Cardiology, University Medical Center Mainz, Johannes Gutenberg University, Germany; German Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Mainz, Germany. Electronic address:

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December 2020

On the Clinical Pharmacology of Reactive Oxygen Species.

Pharmacol Rev 2020 10;72(4):801-828

Department of Pharmacology and Personalized Medicine, Maastricht University, School of Mental Health and Neuroscience (MHeNS), Maastricht, The Netherlands (A.I.C., C.N., A.P., H.H.H.W.S.); H. M. Pharma Consultancy, Wien, Austria (H.A.M.M.); Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), ISCIII, Instituto de Investigaciones Biomédicas "Alberto Sols" UAM-CSIC, Instituto de Investigación Sanitaria La Paz (IdiPaz), Department of Biochemistry, Faculty of Medicine, Autonomous University of Madrid, Madrid, Spain (A.C., A.I.R.); Brighton and Sussex Medical School, Falmer, United Kingdom (P.G.); Department of Pathology and Immunology, Medical School, University of Geneva, Geneva, Switzerland (V.J., F.A.); Microbiology, Bioorganic and Macromolecular Chemistry, RD3, Faculty of Pharmacy, Université Libre de Bruxelles (ULB), Bruxelles, Belgium (F.D., J.S.); and Department of Biomedical Sciences (S.D., M.D.S., F.D.L.) and CNR Neuroscience Institute (N.K., F.D.L.), University of Padova, Padova, Italy

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October 2020

Mitochondrial ion channels as targets for cardioprotection.

J Cell Mol Med 2020 Jul 3;24(13):7102-7114. Epub 2020 Jun 3.

Department of Biomedical Sciences, University of Padova, Padova, Italy.

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July 2020

Regulation of Vascular Function and Inflammation via Cross Talk of Reactive Oxygen and Nitrogen Species from Mitochondria or NADPH Oxidase-Implications for Diabetes Progression.

Int J Mol Sci 2020 May 12;21(10). Epub 2020 May 12.

Center for Cardiology, Department of Cardiology 1, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.

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May 2020

Mitochondrial ROS Formation in the Pathogenesis of Diabetic Cardiomyopathy.

Front Cardiovasc Med 2020 18;7:12. Epub 2020 Feb 18.

Neuroscience Institute, National Research Council of Italy (CNR), Padua, Italy.

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February 2020

Identification of an ATP-sensitive potassium channel in mitochondria.

Nature 2019 08 21;572(7771):609-613. Epub 2019 Aug 21.

Department of Biomedical Sciences, University of Padova, Padova, Italy.

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August 2019

mCerulean3-Based Cameleon Sensor to Explore Mitochondrial Ca Dynamics In Vivo.

iScience 2019 Jun 27;16:340-355. Epub 2019 May 27.

Neuroscience Institute, National Research Council (CNR), 35131 Padua, Italy; Department of Biomedical Sciences, University of Padua, 35131 Padua, Italy; Venetian Institute of Molecular Medicine (VIMM), 35131 Padua, Italy. Electronic address:

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June 2019

Fondation Leducq Transatlantic Network of Excellence Targeting Mitochondria to Treat Heart Disease.

Circ Res 2019 04;124(9):1294-1296

INSERM U060, CarMeN Laboratory, Claude Bernard Lyon 1 University, France and Service d'explorations fonctionnelles Cardiovasculaires, Hôpital Louis Pradel, Hospices Civils de Lyon, France (M.O.).

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April 2019

Measurement of Mitochondrial ROS Formation.

Methods Mol Biol 2018 ;1782:403-418

Department of Biomedical Sciences, University of Padova, Padova, Italy.

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February 2019

Live Cell Imaging in Microfluidic Device Proves Resistance to Oxygen/Glucose Deprivation in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Anal Chem 2018 05 9;90(9):5687-5695. Epub 2018 Apr 9.

Stem Cells & Regenerative Medicine Section , UCL Great Ormond Street Institute of Child Health , 30 Guilford Street , London WC1N 1EH , U.K.

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May 2018

The Rapidly Evolving Concept of Whole Heart Engineering.

Stem Cells Int 2017 9;2017:8920940. Epub 2017 Nov 9.

Cardiovascular Regenerative Medicine Group, Department of Cardiac, Thoracic and Vascular Surgery, University of Padua, Padua, Italy.

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November 2017

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

Authors:
Javier Egea Isabel Fabregat Yves M Frapart Pietro Ghezzi Agnes Görlach Thomas Kietzmann Kateryna Kubaichuk Ulla G Knaus Manuela G Lopez Gloria Olaso-Gonzalez Andreas Petry Rainer Schulz Jose Vina Paul Winyard Kahina Abbas Opeyemi S Ademowo Catarina B Afonso Ioanna Andreadou Haike Antelmann Fernando Antunes Mutay Aslan Markus M Bachschmid Rui M Barbosa Vsevolod Belousov Carsten Berndt David Bernlohr Esther Bertrán Alberto Bindoli Serge P Bottari Paula M Brito Guia Carrara Ana I Casas Afroditi Chatzi Niki Chondrogianni Marcus Conrad Marcus S Cooke João G Costa Antonio Cuadrado Pham My-Chan Dang Barbara De Smet Bilge Debelec-Butuner Irundika H K Dias Joe Dan Dunn Amanda J Edson Mariam El Assar Jamel El-Benna Péter Ferdinandy Ana S Fernandes Kari E Fladmark Ulrich Förstermann Rashid Giniatullin Zoltán Giricz Anikó Görbe Helen Griffiths Vaclav Hampl Alina Hanf Jan Herget Pablo Hernansanz-Agustín Melanie Hillion Jingjing Huang Serap Ilikay Pidder Jansen-Dürr Vincent Jaquet Jaap A Joles Balaraman Kalyanaraman Danylo Kaminskyy Mahsa Karbaschi Marina Kleanthous Lars-Oliver Klotz Bato Korac Kemal Sami Korkmaz Rafal Koziel Damir Kračun Karl-Heinz Krause Vladimír Křen Thomas Krieg João Laranjinha Antigone Lazou Huige Li Antonio Martínez-Ruiz Reiko Matsui Gethin J McBean Stuart P Meredith Joris Messens Verónica Miguel Yuliya Mikhed Irina Milisav Lidija Milković Antonio Miranda-Vizuete Miloš Mojović María Monsalve Pierre-Alexis Mouthuy John Mulvey Thomas Münzel Vladimir Muzykantov Isabel T N Nguyen Matthias Oelze Nuno G Oliveira Carlos M Palmeira Nikoletta Papaevgeniou Aleksandra Pavićević Brandán Pedre Fabienne Peyrot Marios Phylactides Gratiela G Pircalabioru Andrew R Pitt Henrik E Poulsen Ignacio Prieto Maria Pia Rigobello Natalia Robledinos-Antón Leocadio Rodríguez-Mañas Anabela P Rolo Francis Rousset Tatjana Ruskovska Nuno Saraiva Shlomo Sasson Katrin Schröder Khrystyna Semen Tamara Seredenina Anastasia Shakirzyanova Geoffrey L Smith Thierry Soldati Bebiana C Sousa Corinne M Spickett Ana Stancic Marie José Stasia Holger Steinbrenner Višnja Stepanić Sebastian Steven Kostas Tokatlidis Erkan Tuncay Belma Turan Fulvio Ursini Jan Vacek Olga Vajnerova Kateřina Valentová Frank Van Breusegem Lokman Varisli Elizabeth A Veal A Suha Yalçın Olha Yelisyeyeva Neven Žarković Martina Zatloukalová Jacek Zielonka Rhian M Touyz Andreas Papapetropoulos Tilman Grune Santiago Lamas Harald H H W Schmidt Fabio Di Lisa Andreas Daiber

Redox Biol 2017 10 18;13:94-162. Epub 2017 May 18.

Molecular Cardiology, Center for Cardiology, Cardiology 1, University Medical Center Mainz, Mainz, Germany; DZHK (German Centre for Cardiovascular Research), partner site Rhine-Main, Mainz, Germany. Electronic address:

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October 2017

Pharmacology of oxidative stress: translational opportunities.

Br J Pharmacol 2017 06;174(12):1511-1513

Pharmahungary Group, Szeged, Hungary.

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June 2017

Emerging role of monoamine oxidase as a therapeutic target for cardiovascular disease.

Curr Opin Pharmacol 2017 04 18;33:64-69. Epub 2017 May 18.

Neuroscience Institute, National Research Council of Italy (CNR), Via Ugo Bassi 58/B, 35131 Padova, Italy. Electronic address:

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April 2017

Cardioprotection by H2S Donors: Nitric Oxide-Dependent and ‑Independent Mechanisms.

J Pharmacol Exp Ther 2016 09 24;358(3):431-40. Epub 2016 Jun 24.

George P. Livanos and Marianthi Simou Laboratories, First Department of Pulmonary and Critical Care Medicine, Evangelismos Hospital, Faculty of Medicine, National and Kapodistrian University of Athens, Athens, Greece (A.C., A.P.); Laboratory of Pharmacology, Democritus University of Thrace Medical School, Alexandroupolis, Greece (A.C., V.G.M.); Laboratory of Pharmacology, Faculty of Pharmacy, National and Kapodistrian University of Athens, Greece (S.-I.B., I.A., P.E., A.P.); Neuroscience Institute, CNR, Italy (N.K., F.D.L.); Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom (M.E.W.); University of Exeter Medical School, Exeter, United Kingdom (M.W.); Department of Biomedical Sciences, University of Padova, Padova, Italy (F.D.L.); Center of Cardiology and Center for Thrombosis and Hemostasis, Medical Center of the Johannes Gutenberg University, Mainz, Germany (A.D.); Department of Anesthesiology, University of Texas Medical Branch, Galveston, Texas (C.S.); Center of Clinical, Experimental Surgery & Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece (A.P.)

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September 2016

Mitochondrial potassium homeostasis: a central player in cardioprotection.

Cardiovasc Res 2016 May;110(1):4-5

Department of Biomedical Sciences and CNR Institute of Neurosciences, University of Padova, Padova, Italy.

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May 2016

New aspects of p66Shc in ischaemia reperfusion injury and other cardiovascular diseases.

Br J Pharmacol 2017 06 14;174(12):1690-1703. Epub 2016 Apr 14.

Institut für Physiologie, Justus-Liebig Universität Giessen, Giessen, Germany.

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June 2017

Virtual issue by COST Action BM1203 (EU-ROS) "Emerging concepts in redox biology and oxidative stress".

Redox Biol 2016 08 21;8:439-41. Epub 2015 Dec 21.

Department of Cell Biology and Immunology, Centro de Biología Molecular "Severo Ochoa" (CSIC-UAM), Nicolás Cabrera 1, 28049 Madrid, Spain. Electronic address:

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August 2016

Crosstalk of mitochondria with NADPH oxidase via reactive oxygen and nitrogen species signalling and its role for vascular function.

Br J Pharmacol 2017 06 4;174(12):1670-1689. Epub 2016 Feb 4.

Center for Cardiology, Laboratory of Molecular Cardiology, Medical Center of the Johannes Gutenberg University, Mainz, Germany.

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June 2017

Recent Advances on Pathophysiology, Diagnostic and Therapeutic Insights in Cardiac Dysfunction Induced by Antineoplastic Drugs.

Biomed Res Int 2015 25;2015:138148. Epub 2015 Oct 25.

Department of Translational Medical Sciences, Division of Internal Medicine, Federico II University, 80131 Naples, Italy.

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September 2016

Pharmacology and Clinical Drug Candidates in Redox Medicine.

Antioxid Redox Signal 2015 Nov 6;23(14):1113-29. Epub 2015 Nov 6.

1 Cardiovascular Research Institute Maastricht (CARIM), Maastricht University , Maastricht, the Netherlands .

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November 2015

NOX4 in Mitochondria: Yeast Two-Hybrid-Based Interaction with Complex I Without Relevance for Basal Reactive Oxygen Species?

Antioxid Redox Signal 2015 Nov 3;23(14):1106-12. Epub 2015 Aug 3.

5 Department of Pharmacology, CARIM, and Maastricht Institute for Advanced Studies, Maastricht University , Maastricht, The Netherlands .

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November 2015

The OPA1-dependent mitochondrial cristae remodeling pathway controls atrophic, apoptotic, and ischemic tissue damage.

Cell Metab 2015 Jun;21(6):834-44

Dulbecco Telethon Institute, Venetian Institute of Molecular Medicine, Via Orus 2, 35129 Padova, Italy; Department of Biology, University of Padova, Via C. Colombo 3, 35121 Padova, Italy. Electronic address:

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June 2015

Modulation of Mitochondrial Permeability Transition in Ischemia-Reperfusion Injury of the Heart. Advantages and Limitations.

Curr Med Chem 2015 ;22(20):2480-7

Dipartimento di Scienze Biomediche, Via Ugo Bassi 58/B, I-35121 Padova, Italy.

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August 2016

From ATP to PTP and Back: A Dual Function for the Mitochondrial ATP Synthase.

Circ Res 2015 May;116(11):1850-62

From the Department of Biomedical Sciences, University of Padova, Italy (P.B., F.D.L.); and Department of Medical and Biological Sciences (F.F) and Department of Food Science (G.L.), University of Udine, Udine, Italy.

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May 2015

Cardiac Fgf21 synthesis and release: an autocrine loop for boosting up antioxidant defenses in failing hearts.

Cardiovasc Res 2015 Apr 24;106(1):1-3. Epub 2015 Feb 24.

Department of Genetic Biochemistry, Kyoto University Graduate School of Pharmaceutical Sciences, Sakyo, Kyoto 606-8501, Japan

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April 2015

The p66ShcA adaptor protein regulates healing after myocardial infarction.

Basic Res Cardiol 2015 Mar 14;110(2):13. Epub 2015 Feb 14.

Division of Physiology, Department of Molecular Medicine, Institute of Basic Medical Science, University of Oslo, Postbox 1103, Blindern, 0317, Oslo, Norway,

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March 2015

The mitochondrial permeability transition pore: molecular nature and role as a target in cardioprotection.

J Mol Cell Cardiol 2015 Jan 28;78:100-6. Epub 2014 Sep 28.

Department of Biomedical Sciences, University of Padova, 35121 Padova, Italy; Consiglio Nazionale delle Ricerche Neuroscience Institute, University of Padova, 35121 Padova, Italy. Electronic address:

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January 2015

Reactive oxygen species and redox compartmentalization.

Front Physiol 2014 12;5:285. Epub 2014 Aug 12.

Neuroscience Institute, National Research Council of Italy (CNR) Padova, Italy ; Department of Biomedical Sciences, University of Padova Padova, Italy.

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August 2014

Oxidative stress in muscular dystrophy: from generic evidence to specific sources and targets.

J Muscle Res Cell Motil 2014 Feb 12;35(1):23-36. Epub 2014 Mar 12.

Department of Biomedical Sciences, University of Padova, Viale G. Colombo 3, 35131, Padua, Italy,

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February 2014

Monoamine oxidases as sources of oxidants in the heart.

J Mol Cell Cardiol 2014 Aug 9;73:34-42. Epub 2014 Jan 9.

Neuroscience Institute, National Research Council of Italy (CNR), Padua, Italy; Department of Biomedical Sciences, University of Padua, Italy. Electronic address:

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August 2014

Preface to mitochondria and cardioprotection.

Biochim Biophys Acta 2011 Jul;1813(7):1261-2

Department of Biomedical Sciences and CNR Institute of Neuroscience, University of Padova, Viale G. Colombo, 3-35131 Padova, Italy.

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July 2011

The mitochondrial permeability transition pore and cyclophilin D in cardioprotection.

Biochim Biophys Acta 2011 Jul 3;1813(7):1316-22. Epub 2011 Feb 3.

Department of Biomedical Sciences and CNR Institute of Neuroscience, University of Padova, 35121 Padova, Italy.

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July 2011

β₂-Adrenoceptors, NADPH oxidase, ROS and p38 MAPK: another 'radical' road to heart failure?

Br J Pharmacol 2011 Mar;162(5):1009-11

Department of Biomedical Sciences, University of Padova, Padova, Italy.

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March 2011

Oxidation of myofibrillar proteins in human heart failure.

J Am Coll Cardiol 2011 Jan;57(3):300-9

Department of Biomedical Sciences, University of Padova, Italy.

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January 2011

Monoamine oxidases (MAO) in the pathogenesis of heart failure and ischemia/reperfusion injury.

Biochim Biophys Acta 2011 Jul 24;1813(7):1323-32. Epub 2010 Sep 24.

Department of Biomedical Sciences, University of Padova, viale G. Colombo 3, 35121 Padova, Italy.

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July 2011

Mitochondrial injury and protection in ischemic pre- and postconditioning.

Antioxid Redox Signal 2011 Mar 30;14(5):881-91. Epub 2010 Nov 30.

Department of Biomedical Sciences, Università di Padova, Viale G. Colombo 3, Padua, Italy.

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March 2011

Redox regulation of T-cell turnover by the p13 protein of human T-cell leukemia virus type 1: distinct effects in primary versus transformed cells.

Blood 2010 Jul 15;116(1):54-62. Epub 2010 Apr 15.

Department of Oncology and Surgical Sciences, Institute of Neuroscience at the Department of Biomedical Sciences, Università di Padova, Via Gattamelata 64, Padua, Italy.

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July 2010

The cardioprotective effects elicited by p66(Shc) ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury.

Biochim Biophys Acta 2009 Jul 9;1787(7):774-80. Epub 2009 Apr 9.

Department of Biomedical Sciences, University of Padova, Viale G. Colombo 3, 35121 Italy; European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy.

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July 2009

Mitochondria and vascular pathology.

Pharmacol Rep 2009 Jan-Feb;61(1):123-30

Department of Biomedical Sciences, University of Padova, Padova, Italy.

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June 2009

A CaPful of mechanisms regulating the mitochondrial permeability transition.

J Mol Cell Cardiol 2009 Jun 19;46(6):775-80. Epub 2009 Mar 19.

Department of Biomedical Sciences and CNR Institute of Neuroscience, University of Padova, Padova, Italy.

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June 2009

Mitochondrial pathways for ROS formation and myocardial injury: the relevance of p66(Shc) and monoamine oxidase.

Basic Res Cardiol 2009 Mar 26;104(2):131-9. Epub 2009 Feb 26.

Department of Biomedical Sciences, University of Padova, Padova, Italy.

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March 2009

Mitochondrial respiration and membrane potential after low-flow ischemia are not affected by ischemic preconditioning.

J Mol Cell Cardiol 2007 Nov 17;43(5):610-5. Epub 2007 Aug 17.

Institut für Pathophysiologie, Zentrum für Innere Medizin, Universitätsklinikum Essen, Hufelandstr. 55, 45122 Essen, Germany.

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November 2007

Mitochondria and cardioprotection.

Heart Fail Rev 2007 Dec;12(3-4):249-60

Dipartimento di Chimica Biologica, Università di Padova, Viale G. Colombo 3, Padua 35121, Italy.

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December 2007

Mitochondrial dysfunction induced by a cytotoxic adenine dinucleotide produced by ADP-ribosyl cyclases from cADPR.

J Biol Chem 2007 Feb 8;282(7):5045-52. Epub 2006 Dec 8.

Department of Experimental Medicine, Section of Biochemistry, and Center of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV/1, 16132 Genova, Italy.

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February 2007

Formation of reactive oxygen species at increased contraction frequency in rat cardiomyocytes.

Cardiovasc Res 2006 Jul 13;71(2):374-82. Epub 2006 May 13.

Institut für Pathophysiologie, Universitätsklinikum Essen, Hufelandstrasse 55, 45122 Essen, Germany.

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July 2006

Mitochondria and ischemia-reperfusion injury of the heart: fixing a hole.

Cardiovasc Res 2006 May 23;70(2):191-9. Epub 2006 Feb 23.

Dipartimento di Chimica Biologica, Università di Padova, Viale G. Colombo 3, 35121 Padova,

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May 2006

Mitochondrial function and myocardial aging. A critical analysis of the role of permeability transition.

Cardiovasc Res 2005 May;66(2):222-32

Dipartimento di Chimica Biologica, Università di Padova, Viale G. Colombo 3, 35121 Padova, Italy.

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May 2005

Arachidonic acid released by phospholipase A(2) activation triggers Ca(2+)-dependent apoptosis through the mitochondrial pathway.

J Biol Chem 2004 Jun 7;279(24):25219-25. Epub 2004 Apr 7.

Department of Biomedical Sciences, Consiglio Nazionale delle Ricerche Institute of Neuroscience at the University of Padova, Viale Giuseppe Colombo 3, I-35121 Padova, Italy.

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June 2004

Evidence of myofibrillar protein oxidation induced by postischemic reperfusion in isolated rat hearts.

Am J Physiol Heart Circ Physiol 2004 Mar;286(3):H870-7

Dipartimento di Chimica Biologica, Viale G. Colombo, 3, 35121 Padova, Italy.

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March 2004

Mitochondria and reperfusion injury. The role of permeability transition.

Basic Res Cardiol 2003 Jul;98(4):235-41

Istituto di Neuroscienze del CNR, Università di Padova, Viale Giuseppe Colombo 3, 35121 Padua, Italy.

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July 2003

PUVA-induced apoptosis involves mitochondrial dysfunction caused by the opening of the permeability transition pore.

FEBS Lett 2002 Jul;522(1-3):168-72

Dipartimento di Chimica Biologica, Università di Padova, Viale Giuseppe Colombo 3, Italy.

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July 2002