Publications by authors named "Fabio Benfenati"

216 Publications

Neuroinflammation induces synaptic scaling through IL-1β-mediated activation of the transcriptional repressor REST/NRSF.

Cell Death Dis 2021 Feb 15;12(2):180. Epub 2021 Feb 15.

Center for Synaptic Neuroscience and Technology, Istituto Italiano di Tecnologia, Largo Rosanna Benzi 10, 16132, Genova, Italy.

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February 2021

Structural Mechanism of ω-Currents in a Mutated Kv7.2 Voltage Sensor Domain from Molecular Dynamics Simulations.

J Chem Inf Model 2021 Feb 11. Epub 2021 Feb 11.

Center for Synaptic Neuroscience and Technology (NSYN@UniGe), Istituto Italiano di Tecnologia, Largo Rosanna Benzi, 10, 16132 Genova, Italy.

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February 2021

Increased responsiveness at the cerebellar input stage in the PRRT2 knockout model of paroxysmal kinesigenic dyskinesia.

Neurobiol Dis 2021 Jan 28;152:105275. Epub 2021 Jan 28.

Center for Synaptic Neuroscience and Technology, Istituto Italiano di Tecnologia, Largo Rosanna Benzi 10, 16132 Genova, Italy; IRCCS, Ospedale Policlinico San Martino, Largo Rosanna Benzi 10, 16132 Genova, Italy. Electronic address:

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January 2021

Isobaric Labeling Proteomics Allows a High-Throughput Investigation of Protein Corona Orientation.

Anal Chem 2021 01 7;93(2):784-791. Epub 2020 Dec 7.

Analytical Chemistry Lab, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genova, Italy.

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January 2021

Modulation of neuronal firing: what role can nanotechnology play?

Nanomedicine (Lond) 2020 12 16;15(30):2895-2900. Epub 2020 Nov 16.

Center for Synaptic Neuroscience & Technology, Istituto Italiano di Tecnologia, Largo Rosanna Benzi 10, 16132 Genova, Italy.

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December 2020

Dysfunction of the serotonergic system in the brain of synapsin triple knockout mice is associated with behavioral abnormalities resembling synapsin-related human pathologies.

Prog Neuropsychopharmacol Biol Psychiatry 2021 Mar 12;105:110135. Epub 2020 Oct 12.

IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina 58, 20132 Milano, Italy; Department of Psychiatry, McGill University, Montreal, QC, Canada. Electronic address:

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March 2021

Engineering REST-Specific Synthetic PUF Proteins to Control Neuronal Gene Expression: A Combined Experimental and Computational Study.

ACS Synth Biol 2020 08 5;9(8):2039-2054. Epub 2020 Aug 5.

Center for Synaptic Neuroscience and Technology, Istituto Italiano di Tecnologia, Genova 16132, Italy.

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August 2020

Acute knockdown of Depdc5 leads to synaptic defects in mTOR-related epileptogenesis.

Neurobiol Dis 2020 06 27;139:104822. Epub 2020 Feb 27.

Center for Synaptic Neuroscience and Technology, Istituto Italiano di Tecnologia, Largo Rosanna Benzi 10, 16132 Genova, Italy; IRCSS, Ospedale Policlinico San Martino, Largo Rosanna Benzi 10, 16132 Genova, Italy. Electronic address:

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June 2020

Alpha-synuclein/synapsin III pathological interplay boosts the motor response to methylphenidate.

Neurobiol Dis 2020 05 4;138:104789. Epub 2020 Feb 4.

Division of Pharmacology, Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy; Laboratory for Preventive and Personalized Medicine, Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy. Electronic address:

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May 2020

Mild Inactivation of RE-1 Silencing Transcription Factor (REST) Reduces Susceptibility to Kainic Acid-Induced Seizures.

Front Cell Neurosci 2019 10;13:580. Epub 2020 Jan 10.

Center for Synaptic Neuroscience and Technology, Istituto Italiano di Tecnologia, Genova, Italy.

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January 2020

Progress of Induced Pluripotent Stem Cell Technologies to Understand Genetic Epilepsy.

Int J Mol Sci 2020 Jan 12;21(2). Epub 2020 Jan 12.

Department of Experimental Medicine, University of Genova, Viale Benedetto XV, 3, 16132 Genoa, Italy.

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January 2020

Correction: Autoantibodies to synapsin I sequestrate synapsin I and alter synaptic function.

Cell Death Dis 2020 Jan 14;11(1):27. Epub 2020 Jan 14.

Center for Synaptic Neuroscience and Technology, Istituto Italiano di Tecnologia, Largo Rosanna Benzi 10, 16132, Genova, Italy.

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January 2020

Sub-millisecond Control of Neuronal Firing by Organic Light-Emitting Diodes.

Front Bioeng Biotechnol 2019 22;7:278. Epub 2019 Oct 22.

Center for Synaptic Neuroscience and Technology, Istituto Italiano di Tecnologia, Genoa, Italy.

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October 2019

Autoantibodies to synapsin I sequestrate synapsin I and alter synaptic function.

Cell Death Dis 2019 11 14;10(11):864. Epub 2019 Nov 14.

Center for Synaptic Neuroscience and Technology, Istituto Italiano di Tecnologia, Largo Rosanna Benzi 10, 16132, Genova, Italy.

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November 2019

Synapsins are expressed at neuronal and non-neuronal locations in Octopus vulgaris.

Sci Rep 2019 10 28;9(1):15430. Epub 2019 Oct 28.

Center for Micro-BioRobotics & Center for Synaptic Neuroscience and Technology, Istituto Italiano di Tecnologia, Largo Rosanna Benzi 10, 16132, Genova, Italy.

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October 2019

Kidins220/ARMS controls astrocyte calcium signaling and neuron-astrocyte communication.

Cell Death Differ 2020 05 17;27(5):1505-1519. Epub 2019 Oct 17.

Center for Synaptic Neuroscience and Technology, Istituto Italiano di Tecnologia, 16132, Genova, Italy.

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May 2020